product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Cathepsin D antibody produced in mouse
catalog :
C0715
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CTD-19
reactivity :
human, domestic rabbit
application :
western blot, immunohistochemistry - frozen section
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; domestic rabbit; fig 1
  • western blot; domestic rabbit; 1:1000; fig 2
Chen X, Wagener J, Ghribi O, Geiger J. Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer's Disease. Front Aging Neurosci. 2016;8:129 pubmed publisher
Mori F, Miki Y, Kon T, Tanji K, Wakabayashi K. Autophagy Is a Common Degradation Pathway for Bunina Bodies and TDP-43 Inclusions in Amyotrophic Lateral Sclerosis. J Neuropathol Exp Neurol. 2019;78:910-921 pubmed publisher
Anthony Jalin A, Jin R, Wang M, Li G. EPPS treatment attenuates traumatic brain injury in mice by reducing Aβ burden and ameliorating neuronal autophagic flux. Exp Neurol. 2019;314:20-33 pubmed publisher
Bourdenx M, Daniel J, Genin E, Soria F, Blanchard Desce M, Bezard E, et al. Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases. Autophagy. 2016;12:472-83 pubmed publisher
Singh K, Munuganti R, Leblanc E, Lin Y, Leung E, Lallous N, et al. In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α. Breast Cancer Res. 2015;17:27 pubmed publisher
Valcheva P, Cardus A, Panizo S, Parisi E, Bozic M, Lopez Novoa J, et al. Lack of vitamin D receptor causes stress-induced premature senescence in vascular smooth muscle cells through enhanced local angiotensin-II signals. Atherosclerosis. 2014;235:247-55 pubmed publisher
Regauer S, Beham Schmid C. Benign mast cell hyperplasia and atypical mast cell infiltrates in penile lichen planus in adult men. Histol Histopathol. 2014;29:1017-25 pubmed publisher
Tang H, Beer L, Barnhart K, Speicher D. Rapid verification of candidate serological biomarkers using gel-based, label-free multiple reaction monitoring. J Proteome Res. 2011;10:4005-17 pubmed publisher
Schmidt H, Gelhaus C, Nebendahl M, Lettau M, Lucius R, Leippe M, et al. Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells. Cell Commun Signal. 2011;9:4 pubmed publisher
Daryadel A, Grifone R, Simon H, Yousefi S. Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha. J Biol Chem. 2006;281:27653-61 pubmed
Boya P, Andreau K, Poncet D, Zamzami N, Perfettini J, Metivier D, et al. Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J Exp Med. 2003;197:1323-34 pubmed
product information
Product No. :
C0715
Product Name :
Monoclonal Anti-Cathepsin D antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
CTD-19
Applications/Description :
Suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200 using human breast carcinoma tissue; western blot: 1:1,000 using human breast carcinoma cell line extract; microarray; indirect ELISA
Species Reactivity :
human
Isotype :
IgG2a
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA