This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Benserazide hydrochloride
catalog :
B7283
citations: 14
Reference
Wu J, Kung J, Dong J, Chang L, Xie C, Habib A, et al. Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning. Cell Rep. 2019;28:1167-1181.e7 pubmed publisher
Matheoud D, Cannon T, Voisin A, Penttinen A, Ramet L, Fahmy A, et al. Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice. Nature. 2019;571:565-569 pubmed publisher
van Kessel S, Frye A, El Gendy A, Castejon M, Keshavarzian A, van Dijk G, et al. Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson's disease. Nat Commun. 2019;10:310 pubmed publisher
Tomas D, Stanic D, Chua H, White K, Boon W, Horne M. Restoration of the Dopamine Transporter through Cell Therapy Improves Dyskinesia in a Rat Model of Parkinson's Disease. PLoS ONE. 2016;11:e0153424 pubmed publisher
Ren Z, Yang N, Ji C, Zheng J, Wang T, Liu Y, et al. Neuroprotective effects of 5-(4-hydroxy-3-dimethoxybenzylidene)-thiazolidinone in MPTP induced Parkinsonism model in mice. Neuropharmacology. 2015;93:209-18 pubmed publisher
Wienecke J, Ren L, Hultborn H, Chen M, Møller M, Zhang Y, et al. Spinal cord injury enables aromatic L-amino acid decarboxylase cells to synthesize monoamines. J Neurosci. 2014;34:11984-2000 pubmed publisher
Lindenbach D, Palumbo N, Ostock C, Vilceus N, Conti M, Bishop C. Side effect profile of 5-HT treatments for Parkinson's disease and L-DOPA-induced dyskinesia in rats. Br J Pharmacol. 2015;172:119-30 pubmed publisher
Mango D, Bonito Oliva A, Ledonne A, Cappellacci L, Petrelli R, Nisticò R, et al. Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice. Exp Neurol. 2014;261:733-43 pubmed publisher
Wang Y, Wang H, Wang T, Huang C, Liu J. L-DOPA-induced dyskinesia in a rat model of Parkinson's disease is associated with the fluctuational release of norepinephrine in the sensorimotor striatum. J Neurosci Res. 2014;92:1733-45 pubmed publisher
Ko W, Martin Negrier M, Bezard E, Crossman A, Ravenscroft P. RGS4 is involved in the generation of abnormal involuntary movements in the unilateral 6-OHDA-lesioned rat model of Parkinson's disease. Neurobiol Dis. 2014;70:138-48 pubmed publisher
Dragicevic E, Poetschke C, Duda J, Schlaudraff F, Lammel S, Schiemann J, et al. Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons. Brain. 2014;137:2287-302 pubmed publisher
Szczesna K, de la Caridad O, Petazzi P, Soler M, Roa L, Sáez M, et al. Improvement of the Rett syndrome phenotype in a MeCP2 mouse model upon treatment with levodopa and a dopa-decarboxylase inhibitor. Neuropsychopharmacology. 2014;39:2846-56 pubmed publisher
Navailles S, Milan L, Khalki H, Di Giovanni G, Lagière M, De Deurwaerdère P. Noradrenergic terminals regulate L-DOPA-derived dopamine extracellular levels in a region-dependent manner in Parkinsonian rats. CNS Neurosci Ther. 2014;20:671-8 pubmed publisher
Wang Y, Zhang Q, Wang H, Wang T, Liu J. Genome-wide microarray analysis identifies a potential role for striatal retrograde endocannabinoid signaling in the pathogenesis of experimental L-DOPA-induced dyskinesia. Synapse. 2014;68:332-43 pubmed publisher
product information
Catalog Number :
B7283
Product Name :
Benserazide hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (TLC), solid
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA