Strobl C, Schäffer S, Haug T, Völkl S, Peter K, Singer K, et al. Selective PRMT5 Inhibitors Suppress Human CD8+ T Cells by Upregulation of p53 and Impairment of the AKT Pathway Similar to the Tumor Metabolite MTA. Mol Cancer Ther. 2020;19:409-419 pubmed publisher

Ye L, Mueller O, Bagwell J, Bagnat M, Liddle R, Rawls J. High fat diet induces microbiota-dependent silencing of enteroendocrine cells. elife. 2019;8: pubmed publisher

Ryan A, Chan C, Graner F, Hiiragi T. Lumen Expansion Facilitates Epiblast-Primitive Endoderm Fate Specification during Mouse Blastocyst Formation. Dev Cell. 2019;51:684-697.e4 pubmed publisher

Menares E, Gálvez Cancino F, Cáceres Morgado P, Ghorani E, Lopez E, Diaz X, et al. Tissue-resident memory CD8+ T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells. Nat Commun. 2019;10:4401 pubmed publisher

Bravo San Pedro J, Sica V, Martins I, Pol J, Loos F, Maiuri M, et al. Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity. Cell Metab. 2019;30:754-767.e9 pubmed publisher

Pällmann N, Livgård M, Tesikova M, Zeynep Nenseth H, Akkus E, Sikkeland J, et al. Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer. Oncogene. 2019;38:6301-6318 pubmed publisher

Klicznik M, Morawski P, Höllbacher B, Varkhande S, Motley S, Kuri Cervantes L, et al. Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals. Sci Immunol. 2019;4: pubmed publisher

Rafique A, Etzerodt A, Graversen J, Moestrup S, Dagnæs Hansen F, Møller H. Targeted lipid nanoparticle delivery of calcitriol to human monocyte-derived macrophages in vitro and in vivo: investigation of the anti-inflammatory effects of calcitriol. Int J Nanomedicine. 2019;14:2829-2846 pubmed publisher

Bangaru S, Lang S, Schotsaert M, Vanderven H, Zhu X, Kose N, et al. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface. Cell. 2019;177:1136-1152.e18 pubmed publisher

Sutherland Deveen M, Wang T, Lamothe S, Tschirhart J, Guo J, Li W, et al. Differential Regulation of Human Ether-à-Go-Go-Related Gene (hERG) Current and Expression by Activation of Protein Kinase C. Mol Pharmacol. 2019;96:1-12 pubmed publisher

Rosales Ramirez R, Ludert J. The Dengue Virus Nonstructural Protein 1 (NS1) Is Secreted from Mosquito Cells in Association with the Intracellular Cholesterol Transporter Chaperone Caveolin Complex. J Virol. 2019;93: pubmed publisher

Gomes da Silva L, Zhao L, Bezu L, Zhou H, Sauvat A, Liu P, et al. Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus. EMBO J. 2018;37: pubmed publisher

Carpier J, Zucchetti A, Bataille L, Dogniaux S, Shafaq Zadah M, Bardin S, et al. Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation. J Exp Med. 2018;215:1245-1265 pubmed publisher

Cagalinec M, Liiv M, Hodurova Z, Hickey M, Vaarmann A, Mandel M, et al. Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome. PLoS Biol. 2016;14:e1002511 pubmed publisher

Li X, Wang J, Cao J, Ma L, Xu J. Immunoregulation of Bone Marrow-Derived Mesenchymal Stem Cells on the Chronic Cigarette Smoking-Induced Lung Inflammation in Rats. Biomed Res Int. 2015;2015:932923 pubmed publisher

Hussien Y, Podojil J, Robinson A, Lee A, Miller S, Popko B. ER Chaperone BiP/GRP78 Is Required for Myelinating Cell Survival and Provides Protection during Experimental Autoimmune Encephalomyelitis. J Neurosci. 2015;35:15921-33 pubmed publisher

Petrosyan A, Cheng P, Clemens D, Casey C. Downregulation of the small GTPase SAR1A: a key event underlying alcohol-induced Golgi fragmentation in hepatocytes. Sci Rep. 2015;5:17127 pubmed publisher

Na Y, Jung D, Gu G, Jang A, Suh Y, Seok S. The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophages suppresses interleukin-10 production. Sci Signal. 2015;8:ra121 pubmed publisher

Islas Vazquez L, Prado Garcia H, Aguilar Cazares D, Meneses Flores M, Galicia Velasco M, Romero Garcia S, et al. LAP TGF-Beta Subset of CD4(+)CD25(+)CD127(-) Treg Cells is Increased and Overexpresses LAP TGF-Beta in Lung Adenocarcinoma Patients. Biomed Res Int. 2015;2015:430943 pubmed publisher

Abdel Hadi L, Di Vito C, Marfia G, Ferraretto A, Tringali C, Viani P, et al. Sphingosine Kinase 2 and Ceramide Transport as Key Targets of the Natural Flavonoid Luteolin to Induce Apoptosis in Colon Cancer Cells. PLoS ONE. 2015;10:e0143384 pubmed publisher

Zhu H, Lou C, Liu P. Interleukin-27 ameliorates coxsackievirus-B3-induced viral myocarditis by inhibiting Th17 cells. Virol J. 2015;12:189 pubmed publisher

Garcia Knight M, Nduati E, Hassan A, Gambo F, Odera D, Etyang T, et al. Altered Memory T-Cell Responses to Bacillus Calmette-Guerin and Tetanus Toxoid Vaccination and Altered Cytokine Responses to Polyclonal Stimulation in HIV-Exposed Uninfected Kenyan Infants. PLoS ONE. 2015;10:e0143043 pubmed publisher

Gupta J, Pathak M, Misra S, Misra Bhattacharya S. Immunogenicity and Protective Efficacy of Brugia malayi Heavy Chain Myosin as Homologous DNA, Protein and Heterologous DNA/Protein Prime Boost Vaccine in Rodent Model. PLoS ONE. 2015;10:e0142548 pubmed publisher

Dwyer M, Zivadinov R, Tao Y, Zhang X, Kennedy C, Bergsland N, et al. Immunological and short-term brain volume changes in relapsing forms of multiple sclerosis treated with interferon beta-1a subcutaneously three times weekly: an open-label two-arm trial. BMC Neurol. 2015;15:232 pubmed publisher

Martínez Núñez L, Riquelme M. Role of BGT-1 and BGT-2, two predicted GPI-anchored glycoside hydrolases/glycosyltransferases, in cell wall remodeling in Neurospora crassa. Fungal Genet Biol. 2015;85:58-70 pubmed publisher

Kang J, Dervan P. A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma. Q Rev Biophys. 2015;48:453-64 pubmed publisher

Zhang K, Ge Z, Xue Z, Huang W, Mei M, Zhang Q, et al. Chrysin suppresses human CD14(+) monocyte-derived dendritic cells and ameliorates experimental autoimmune encephalomyelitis. J Neuroimmunol. 2015;288:13-20 pubmed publisher

Gharagozloo M, Mahvelati T, Imbeault E, Gris P, Zerif E, Bobbala D, et al. The nod-like receptor, Nlrp12, plays an anti-inflammatory role in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2015;12:198 pubmed publisher

Leyking S, Wolf M, Mihm J, Schaefer M, Bohle R, Fliser D, et al. Alloreactive T Cells to Identify Risk HLA Alleles for Retransplantation After Acute Accelerated Steroid-Resistant Rejection. Transplant Proc. 2015;47:2425-32 pubmed publisher

Smaldini P, Orsini Delgado M, Fossati C, Docena G. Orally-Induced Intestinal CD4+ CD25+ FoxP3+ Treg Controlled Undesired Responses towards Oral Antigens and Effectively Dampened Food Allergic Reactions. PLoS ONE. 2015;10:e0141116 pubmed publisher

Kumar J, Holmberg C, Balabanova S, Borysova L, Burdyga T, Beynon R, et al. Mesenchymal Stem Cells Exhibit Regulated Exocytosis in Response to Chemerin and IGF. PLoS ONE. 2015;10:e0141331 pubmed publisher

Macabuag N, Dolphin A. Alternative Splicing in Ca(V)2.2 Regulates Neuronal Trafficking via Adaptor Protein Complex-1 Adaptor Protein Motifs. J Neurosci. 2015;35:14636-52 pubmed publisher

Li C, Luo X, Lin Y, Tang X, Ling L, Wang L, et al. A Higher Frequency of CD14+ CD169+ Monocytes/Macrophages in Patients with Colorectal Cancer. PLoS ONE. 2015;10:e0141817 pubmed publisher

Fang W, Lai S, Lai W, Lee M, Liao C, Ke F, et al. CRTC2 and Nedd4 ligase involvement in FSH and TGFβ1 upregulation of connexin43 gap junction. J Mol Endocrinol. 2015;55:263-75 pubmed publisher

Gupta P, Godec J, Wolski D, Adland E, Yates K, Pauken K, et al. CD39 Expression Identifies Terminally Exhausted CD8+ T Cells. PLoS Pathog. 2015;11:e1005177 pubmed publisher

Jakubiuk Tomaszuk A, Sobaniec W, Rusak M, Poskrobko E, Nędzi A, Olchowik B, et al. Decrease of interleukin (IL)17A gene expression in leucocytes and in the amount of IL-17A protein in CD4+ T cells in children with Down Syndrome. Pharmacol Rep. 2015;67:1130-4 pubmed publisher

Matz M, Fabritius K, Liu J, LORKOWSKI C, Brakemeier S, Unterwalder N, et al. Conversion to Belatacept based regimen does not change T-cell phenotype and function in renal transplantation. Transpl Immunol. 2015;33:176-84 pubmed publisher

Seshadri C, Lin L, Scriba T, Peterson G, Freidrich D, Frahm N, et al. T Cell Responses against Mycobacterial Lipids and Proteins Are Poorly Correlated in South African Adolescents. J Immunol. 2015;195:4595-603 pubmed publisher

Black L, Srivastava R, Schoeb T, Moore R, Barnes S, KABAROWSKI J. Cholesterol-Independent Suppression of Lymphocyte Activation, Autoimmunity, and Glomerulonephritis by Apolipoprotein A-I in Normocholesterolemic Lupus-Prone Mice. J Immunol. 2015;195:4685-98 pubmed publisher

Schulz A, Mälzer J, Domingo C, Jürchott K, Grützkau A, Babel N, et al. Low Thymic Activity and Dendritic Cell Numbers Are Associated with the Immune Response to Primary Viral Infection in Elderly Humans. J Immunol. 2015;195:4699-711 pubmed publisher

Salmond R, Brownlie R, Meyuhas O, Zamoyska R. Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 Phosphorylation. J Immunol. 2015;195:4615-22 pubmed publisher

Lorenzo C, Pérez Chacón G, Garaulet G, Mallorquín Z, Zapata J, Rodríguez A. Efficient expression of bioactive murine IL12 as a self-processing P2A polypeptide driven by inflammation-regulated promoters in tumor cell lines. Cancer Gene Ther. 2015;22:542-51 pubmed publisher

Li C, Munitic I, Mittelstadt P, Castro E, Ashwell J. Suppression of Dendritic Cell-Derived IL-12 by Endogenous Glucocorticoids Is Protective in LPS-Induced Sepsis. PLoS Biol. 2015;13:e1002269 pubmed publisher

Bollampalli V, Harumi Yamashiro L, Feng X, Bierschenk D, Gao Y, Blom H, et al. BCG Skin Infection Triggers IL-1R-MyD88-Dependent Migration of EpCAMlow CD11bhigh Skin Dendritic cells to Draining Lymph Node During CD4+ T-Cell Priming. PLoS Pathog. 2015;11:e1005206 pubmed publisher

You R, Lu W, Shan M, Berlin J, Samuel E, Marcano D, et al. Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema. elife. 2015;4:e09623 pubmed publisher

Zhou Z, Yu X, Zhang J, Tian Z, Zhang C. TLR7/8 agonists promote NK-DC cross-talk to enhance NK cell anti-tumor effects in hepatocellular carcinoma. Cancer Lett. 2015;369:298-306 pubmed publisher

Anz D, Rapp M, Eiber S, Koelzer V, Thaler R, Haubner S, et al. Suppression of intratumoral CCL22 by type i interferon inhibits migration of regulatory T cells and blocks cancer progression. Cancer Res. 2015;75:4483-93 pubmed publisher

Wang J, Tao Q, Wang H, Wang Z, Wu F, Pan Y, et al. Elevated IL-35 in bone marrow of the patients with acute myeloid leukemia. Hum Immunol. 2015;76:681-6 pubmed publisher

Caperton C, Agrawal S, Gupta S. Good syndrome presenting with CD8⁺ T-Cell large granular lymphocyte leukemia. Oncotarget. 2015;6:36577-86 pubmed publisher

Collins T, Ylanko J, Geng F, Andrews D. A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image Analysis. Assay Drug Dev Technol. 2015;13:547-57 pubmed publisher

Dietrich J, Roy S, Rosenkrands I, Lindenstrøm T, Filskov J, Rasmussen E, et al. Differential influence of nutrient-starved Mycobacterium tuberculosis on adaptive immunity results in progressive tuberculosis disease and pathology. Infect Immun. 2015;83:4731-9 pubmed publisher

Unger W, Mayer C, Engels S, Hesse C, Perdicchio M, Puttur F, et al. Antigen targeting to dendritic cells combined with transient regulatory T cell inhibition results in long-term tumor regression. Oncoimmunology. 2015;4:e970462 pubmed

Horiuchi Y, Takagi A, Uchida T, Akatsuka T. Targeting cryptic epitope with modified antigen coupled to the surface of liposomes induces strong antitumor CD8 T-cell immune responses in vivo. Oncol Rep. 2015;34:2827-36 pubmed publisher

Cortez Espinosa N, Cortés Garcia J, Martínez Leija E, Rodríguez Rivera J, Barajas López C, González Amaro R, et al. CD39 expression on Treg and Th17 cells is associated with metabolic factors in patients with type 2 diabetes. Hum Immunol. 2015;76:622-30 pubmed publisher

Shourian M, Flaczyk A, Angers I, Mindt B, Fritz J, Qureshi S. The Cnes2 locus on mouse chromosome 17 regulates host defense against cryptococcal infection through pleiotropic effects on host immunity. Infect Immun. 2015;83:4541-54 pubmed publisher

Guo A, He D, Xu H, Geng C, Zhao J. Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents. Sci Rep. 2015;5:14046 pubmed publisher

Liravi B, Piedrafita D, Nguyen G, Bischof R. Dynamics of IL-4 and IL-13 expression in the airways of sheep following allergen challenge. BMC Pulm Med. 2015;15:101 pubmed publisher

Hassan S, Akram M, King E, Dockrell H, Cliff J. PD-1, PD-L1 and PD-L2 Gene Expression on T-Cells and Natural Killer Cells Declines in Conjunction with a Reduction in PD-1 Protein during the Intensive Phase of Tuberculosis Treatment. PLoS ONE. 2015;10:e0137646 pubmed publisher

Mukherjee R, Kanti Barman P, Kumar Thatoi P, Tripathy R, Kumar Das B, Ravindran B. Non-Classical monocytes display inflammatory features: Validation in Sepsis and Systemic Lupus Erythematous. Sci Rep. 2015;5:13886 pubmed publisher

Esposito S, Garziano M, Rainone V, Trabattoni D, Biasin M, Senatore L, et al. Immunomodulatory activity of pidotimod administered with standard antibiotic therapy in children hospitalized for community-acquired pneumonia. J Transl Med. 2015;13:288 pubmed publisher

Gibson D, Elliott L, McDermott E, Tosetto M, Keegan D, Byrne K, et al. Heightened Expression of CD39 by Regulatory T Lymphocytes Is Associated with Therapeutic Remission in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2015;21:2806-14 pubmed publisher

Catelas I, Lehoux E, Hurda I, Baskey S, Gala L, Foster R, et al. Do patients with a failed metal-on-metal hip implant with a pseudotumor present differences in their peripheral blood lymphocyte subpopulations?. Clin Orthop Relat Res. 2015;473:3903-14 pubmed publisher

Certal M, Vinhas A, Pinheiro A, Ferreirinha F, Barros Barbosa A, Silva I, et al. Calcium signaling and the novel anti-proliferative effect of the UTP-sensitive P2Y11 receptor in rat cardiac myofibroblasts. Cell Calcium. 2015;58:518-33 pubmed publisher

Wang X, Huang Z, Chen Y, Lu X, Zhu P, Wen K, et al. A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus. PLoS ONE. 2015;10:e0136888 pubmed publisher

Sun W, Wei X, Niu A, Ma X, Li J, Gao D. Enhanced anti-colon cancer immune responses with modified eEF2-derived peptides. Cancer Lett. 2015;369:112-23 pubmed publisher

Erdmann N, Du V, Carlson J, Schaefer M, Jureka A, Sterrett S, et al. HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses. PLoS Pathog. 2015;11:e1005111 pubmed publisher

Rosenheinrich M, Heine W, Schmühl C, Pisano F, Dersch P. Natural Killer Cells Mediate Protection against Yersinia pseudotuberculosis in the Mesenteric Lymph Nodes. PLoS ONE. 2015;10:e0136290 pubmed publisher

Tao Y, Lin F, Yan X, Gao X, Teng F, Fu Z, et al. Galectin-9 in Combination With EX-527 Prolongs the Survival of Cardiac Allografts in Mice After Cardiac Transplantation. Transplant Proc. 2015;47:2003-9 pubmed publisher

Muthumani K, Falzarano D, Reuschel E, Tingey C, Flingai S, Villarreal D, et al. A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates. Sci Transl Med. 2015;7:301ra132 pubmed publisher

Gimblet C, Loesche M, Carvalho L, Carvalho E, Grice E, Artis D, et al. IL-22 Protects against Tissue Damage during Cutaneous Leishmaniasis. PLoS ONE. 2015;10:e0134698 pubmed publisher

Xu H, Wang X, Lackner A, Veazey R. Type 3 innate lymphoid cell depletion is mediated by TLRs in lymphoid tissues of simian immunodeficiency virus-infected macaques. FASEB J. 2015;29:5072-80 pubmed publisher

Tang Y, Peng L, Qin G, Sun J, Xu L, Jiang Y. CD4(+)CD25(-)Foxp3(+) T cells play a role in tuberculous hydrothorax rather than malignant hydrothorax. J Transl Med. 2015;13:268 pubmed publisher

Yu W, Ge M, Lu S, Shi J, Li X, Zhang J, et al. Anti-inflammatory effects of interleukin-35 in acquired aplastic anemia. Cytokine. 2015;76:409-416 pubmed publisher

Gardner D, Jeffery L, Soskic B, Briggs Z, Hou T, Raza K, et al. 1,25(OH)2D3 Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept. J Immunol. 2015;195:2657-65 pubmed publisher

Nowakowska J, Stuehler C, Egli A, Battegay M, Rauser G, Bantug G, et al. T cells specific for different latent and lytic viral proteins efficiently control Epstein-Barr virus-transformed B cells. Cytotherapy. 2015;17:1280-91 pubmed publisher

Taylor G, Thom M, Capone S, Pierantoni A, Guzman E, Herbert R, et al. Efficacy of a virus-vectored vaccine against human and bovine respiratory syncytial virus infections. Sci Transl Med. 2015;7:300ra127 pubmed publisher

Yang C, Guo N, Liu J, Yang J, Zhu K, Xiao H, et al. Non-classical MHC I-E negatively regulates macrophage activation and Th17 cell development in NOD mice. Sci Rep. 2015;5:12941 pubmed publisher

Khaznadar Z, Boissel N, Agaugué S, Henry G, Cheok M, Vignon M, et al. Defective NK Cells in Acute Myeloid Leukemia Patients at Diagnosis Are Associated with Blast Transcriptional Signatures of Immune Evasion. J Immunol. 2015;195:2580-90 pubmed publisher

Gaur P, Misra R, Aggarwal A. Natural killer cell and gamma delta T cell alterations in enthesitis related arthritis category of juvenile idiopathic arthritis. Clin Immunol. 2015;161:163-9 pubmed publisher

Foley K, Rucki A, Xiao Q, Zhou D, Leubner A, Mo G, et al. Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer. Sci Signal. 2015;8:ra77 pubmed publisher

Huijts C, Schneiders F, Garcia Vallejo J, Verheul H, de Gruijl T, van der Vliet H. mTOR Inhibition Per Se Induces Nuclear Localization of FOXP3 and Conversion of Invariant NKT (iNKT) Cells into Immunosuppressive Regulatory iNKT Cells. J Immunol. 2015;195:2038-45 pubmed publisher

Dende C, Meena J, Nagarajan P, Panda A, Rangarajan P, Padmanaban G. Simultaneously targeting inflammatory response and parasite sequestration in brain to treat Experimental Cerebral Malaria. Sci Rep. 2015;5:12671 pubmed publisher

Hoang M, Lee H, Lee H, Jung S, Choi N, Vo M, et al. Branched Polyethylenimine-Superparamagnetic Iron Oxide Nanoparticles (bPEI-SPIONs) Improve the Immunogenicity of Tumor Antigens and Enhance Th1 Polarization of Dendritic Cells. J Immunol Res. 2015;2015:706379 pubmed publisher

Schnorfeil F, Lichtenegger F, Emmerig K, Schlueter M, Neitz J, Draenert R, et al. T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment. J Hematol Oncol. 2015;8:93 pubmed publisher

Meijers R, Litjens N, Hesselink D, Langerak A, Baan C, Betjes M. Primary Cytomegalovirus Infection Significantly Impacts Circulating T Cells in Kidney Transplant Recipients. Am J Transplant. 2015;15:3143-56 pubmed publisher

Forghani P, Waller E. Poly (I: C) modulates the immunosuppressive activity of myeloid-derived suppressor cells in a murine model of breast cancer. Breast Cancer Res Treat. 2015;153:21-30 pubmed publisher

Bai A, Kokkotou E, Zheng Y, Robson S. Role of acid sphingomyelinase bioactivity in human CD4+ T-cell activation and immune responses. Cell Death Dis. 2015;6:e1828 pubmed publisher

Strauss Albee D, Fukuyama J, Liang E, Yao Y, Jarrell J, Drake A, et al. Human NK cell repertoire diversity reflects immune experience and correlates with viral susceptibility. Sci Transl Med. 2015;7:297ra115 pubmed publisher

Coppola M, van den Eeden S, Wilson L, Franken K, Ottenhoff T, Geluk A. Synthetic Long Peptide Derived from Mycobacterium tuberculosis Latency Antigen Rv1733c Protects against Tuberculosis. Clin Vaccine Immunol. 2015;22:1060-9 pubmed publisher

Kaminsky L, Sei J, Parekh N, Davies M, Reider I, Krouse T, et al. Redundant Function of Plasmacytoid and Conventional Dendritic Cells Is Required To Survive a Natural Virus Infection. J Virol. 2015;89:9974-85 pubmed publisher

Lisovsky I, Isitman G, Song R, DaFonseca S, Tremblay McLean A, Lebouché B, et al. A Higher Frequency of NKG2A+ than of NKG2A- NK Cells Responds to Autologous HIV-Infected CD4 Cells irrespective of Whether or Not They Coexpress KIR3DL1. J Virol. 2015;89:9909-19 pubmed publisher

Bozinovski S, Seow H, Chan S, Anthony D, McQualter J, Hansen M, et al. Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice. Clin Sci (Lond). 2015;129:785-96 pubmed publisher

Kreit M, Vertommen D, Gillet L, Michiels T. The Interferon-Inducible Mouse Apolipoprotein L9 and Prohibitins Cooperate to Restrict Theiler's Virus Replication. PLoS ONE. 2015;10:e0133190 pubmed publisher

Flesch I, Hollett N, Wong Y, Quinan B, Howard D, da Fonseca F, et al. Extent of Systemic Spread Determines CD8+ T Cell Immunodominance for Laboratory Strains, Smallpox Vaccines, and Zoonotic Isolates of Vaccinia Virus. J Immunol. 2015;195:2263-72 pubmed publisher

Weiskopf D, Bangs D, Sidney J, Kolla R, De Silva A, de Silva A, et al. Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with protective immunity. Proc Natl Acad Sci U S A. 2015;112:E4256-63 pubmed publisher

Kelsen J, Dawany N, Moran C, Petersen B, Sarmady M, Sasson A, et al. Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease. Gastroenterology. 2015;149:1415-24 pubmed publisher

Marchant E, Kan B, Sharma A, van Zanten A, Kollmann T, Brant R, et al. Attenuated innate immune defenses in very premature neonates during the neonatal period. Pediatr Res. 2015;78:492-7 pubmed publisher

Messmann J, Reisser T, Leithäuser F, Lutz M, Debatin K, Strauss G. In vitro-generated MDSCs prevent murine GVHD by inducing type 2 T cells without disabling antitumor cytotoxicity. Blood. 2015;126:1138-48 pubmed publisher

Shehade H, Acolty V, Moser M, Oldenhove G. Cutting Edge: Hypoxia-Inducible Factor 1 Negatively Regulates Th1 Function. J Immunol. 2015;195:1372-6 pubmed publisher

Conrad K, Wu P, Sieper J, Syrbe U. In vivo pre-activation of monocytes in patients with axial spondyloarthritis. Arthritis Res Ther. 2015;17:179 pubmed publisher

Kim B, Sasaki Y, Egawa T. Restriction of Nonpermissive RUNX3 Protein Expression in T Lymphocytes by the Kozak Sequence. J Immunol. 2015;195:1517-23 pubmed publisher

Koyama M, Cheong M, Markey K, Gartlan K, Kuns R, Locke K, et al. Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease. J Exp Med. 2015;212:1303-21 pubmed publisher

Kamigaki T, Ibe H, Okada S, Matsuda E, Tanaka M, Oguma E, et al. Improvement of Impaired Immunological Status of Patients with Various Types of Advanced Cancers by Autologous Immune Cell Therapy. Anticancer Res. 2015;35:4535-43 pubmed

Gambarte Tudela J, Capmany A, Romao M, Quintero C, Miserey Lenkei S, Raposo G, et al. The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions. J Cell Sci. 2015;128:3068-81 pubmed publisher

Seong Y, Sung P, Jang Y, Choi Y, Park B, Park S, et al. Activation of human natural killer cells by the soluble form of cellular prion protein. Biochem Biophys Res Commun. 2015;464:512-8 pubmed publisher

Toma M, Wehner R, Kloß A, Hübner L, Fodelianaki G, Erdmann K, et al. Accumulation of tolerogenic human 6-sulfo LacNAc dendritic cells in renal cell carcinoma is associated with poor prognosis. Oncoimmunology. 2015;4:e1008342 pubmed

Di Lullo G, Marcatti M, Heltai S, Brunetto E, Tresoldi C, Bondanza A, et al. Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival. Oncoimmunology. 2015;4:e1005460 pubmed

Guerville F, Daburon S, Marlin R, Lartigue L, Loizon S, Pitard V, et al. TCR-dependent sensitization of human γδ T cells to non-myeloid IL-18 in cytomegalovirus and tumor stress surveillance. Oncoimmunology. 2015;4:e1003011 pubmed

Zhou J, Feng G, Beeson J, Hogarth P, Rogerson S, Yan Y, et al. CD14(hi)CD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so. BMC Med. 2015;13:154 pubmed publisher

Marquez E, Kane K. Identities of P2 and P3 Residues of H-2Kb-Bound Peptides Determine Mouse Ly49C Recognition. PLoS ONE. 2015;10:e0131308 pubmed publisher

Chen M, Liang D, Zuo A, Shao H, Kaplan H, Sun D. An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation. PLoS ONE. 2015;10:e0132348 pubmed publisher

Miyata S, Inoue J, Shimizu M, Sato R. Xanthohumol Improves Diet-induced Obesity and Fatty Liver by Suppressing Sterol Regulatory Element-binding Protein (SREBP) Activation. J Biol Chem. 2015;290:20565-79 pubmed publisher

Cany J, van der Waart A, Spanholtz J, Tordoir M, Jansen J, van der Voort R, et al. Combined IL-15 and IL-12 drives the generation of CD34+-derived natural killer cells with superior maturation and alloreactivity potential following adoptive transfer. Oncoimmunology. 2015;4:e1017701 pubmed

Friedrich P, Sattler A, Muller K, Nienen M, Reinke P, Babel N. Comparing Humoral and Cellular Immune Response Against HBV Vaccine in Kidney Transplant Patients. Am J Transplant. 2015;15:3157-65 pubmed publisher

Alhajjat A, Strong B, Lee A, Turner L, Wadhwani R, Ortaldo J, et al. Prenatal Allospecific NK Cell Tolerance Hinges on Instructive Allorecognition through the Activating Receptor during Development. J Immunol. 2015;195:1506-16 pubmed publisher

Cardoso F, Castro F, Moreira Teixeira L, Sousa J, Torrado E, Silvestre R, et al. Myeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control. PLoS ONE. 2015;10:e0131904 pubmed publisher

Jeffery L, Qureshi O, Gardner D, Hou T, Briggs Z, Soskic B, et al. Vitamin D Antagonises the Suppressive Effect of Inflammatory Cytokines on CTLA-4 Expression and Regulatory Function. PLoS ONE. 2015;10:e0131539 pubmed publisher

Thompson E, Liang F, Lindgren G, Sandgren K, Quinn K, Darrah P, et al. Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Nonhuman Primates. J Immunol. 2015;195:1015-24 pubmed publisher

Reihani H, Rastin M, Mahmoudi M, Ghoryani M, Abdollahi N, Tabasi N, et al. Influence of 1 Alpha, 25-Dihydroxyvitamin D3 on T Helper 17 Cells and Related Cytokines in Systemic Lupus Erythematosus. Iran J Immunol. 2015;12:82-93 pubmed publisher

Ito D, Nojima S, Nishide M, Okuno T, Takamatsu H, Kang S, et al. mTOR Complex Signaling through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+ T Cells. J Immunol. 2015;195:934-43 pubmed publisher

Iyer S, Gangadhara S, Victor B, Gomez R, Basu R, Hong J, et al. Codelivery of Envelope Protein in Alum with MVA Vaccine Induces CXCR3-Biased CXCR5+ and CXCR5- CD4 T Cell Responses in Rhesus Macaques. J Immunol. 2015;195:994-1005 pubmed publisher

Derouazi M, Di Berardino Besson W, Belnoue E, Hoepner S, Walther R, Benkhoucha M, et al. Novel Cell-Penetrating Peptide-Based Vaccine Induces Robust CD4+ and CD8+ T Cell-Mediated Antitumor Immunity. Cancer Res. 2015;75:3020-31 pubmed publisher

Boks M, Unger W, Engels S, Ambrosini M, Kooyk Y, Luttge R. Controlled release of a model vaccine by nanoporous ceramic microneedle arrays. Int J Pharm. 2015;491:375-83 pubmed publisher

Martínez V, Sacedón R, Hidalgo L, Valencia J, Fernández Sevilla L, Hernández López C, et al. The BMP Pathway Participates in Human Naive CD4+ T Cell Activation and Homeostasis. PLoS ONE. 2015;10:e0131453 pubmed publisher

Vaeth M, Zee I, Concepcion A, Maus M, Shaw P, Portal Celhay C, et al. Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells. J Immunol. 2015;195:1202-17 pubmed publisher

Kasztelan Szczerbińska B, Surdacka A, Celiński K, Roliński J, Zwolak A, Miącz S, et al. Prognostic Significance of the Systemic Inflammatory and Immune Balance in Alcoholic Liver Disease with a Focus on Gender-Related Differences. PLoS ONE. 2015;10:e0128347 pubmed publisher

Tähtinen S, Kaikkonen S, Merisalo Soikkeli M, Grönberg Vähä Koskela S, Kanerva A, Parviainen S, et al. Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors. PLoS ONE. 2015;10:e0131242 pubmed publisher

Sommer A, Fabri M. Vitamin D regulates cytokine patterns secreted by dendritic cells to promote differentiation of IL-22-producing T cells. PLoS ONE. 2015;10:e0130395 pubmed publisher

Kato Y, Zaid A, Davey G, Mueller S, Nutt S, Zotos D, et al. Targeting Antigen to Clec9A Primes Follicular Th Cell Memory Responses Capable of Robust Recall. J Immunol. 2015;195:1006-14 pubmed publisher

Damjanovic D, Khera A, Afkhami S, Lai R, Zganiacz A, Jeyanathan M, et al. Age at Mycobacterium bovis BCG Priming Has Limited Impact on Anti-Tuberculosis Immunity Boosted by Respiratory Mucosal AdHu5Ag85A Immunization in a Murine Model. PLoS ONE. 2015;10:e0131175 pubmed publisher

Li G, Ju J, Weyand C, Goronzy J. Age-Associated Failure To Adjust Type I IFN Receptor Signaling Thresholds after T Cell Activation. J Immunol. 2015;195:865-74 pubmed publisher

Chawansuntati K, Chotirosniramit N, Sugandhavesa P, Aurpibul L, Thetket S, Kosashunhanan N, et al. Low expression of activation marker CD69 and chemokine receptors CCR5 and CXCR3 on memory T cells after 2009 H1N1 influenza A antigen stimulation in vitro following H1N1 vaccination of HIV-infected individuals. Hum Vaccin Immunother. 2015;11:2253-65 pubmed publisher

D Osualdo A, Anania V, Yu K, Lill J, Kaufman R, Matsuzawa S, et al. Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress. PLoS ONE. 2015;10:e0130635 pubmed publisher

Poon G, Dong Y, Marshall K, Arif A, Deeg C, Dosanjh M, et al. Hyaluronan Binding Identifies a Functionally Distinct Alveolar Macrophage-like Population in Bone Marrow-Derived Dendritic Cell Cultures. J Immunol. 2015;195:632-42 pubmed publisher

Wise M, Hutnick N, Pollara J, Myles D, Williams C, Yan J, et al. An Enhanced Synthetic Multiclade DNA Prime Induces Improved Cross-Clade-Reactive Functional Antibodies when Combined with an Adjuvanted Protein Boost in Nonhuman Primates. J Virol. 2015;89:9154-66 pubmed publisher

Okita Y, Ohira M, Tanaka H, Tokumoto M, Go Y, Sakurai K, et al. Alteration of CD4 T cell subsets in metastatic lymph nodes of human gastric cancer. Oncol Rep. 2015;34:639-47 pubmed publisher

La Claire J, Manning S, Talarski A. Semi-quantitative assay for polyketide prymnesins isolated from Prymnesium parvum (Haptophyta) cultures. Toxicon. 2015;102:74-80 pubmed publisher

Jones S, Perera D, Fan H, Russ B, Harris J, Morand E. GILZ regulates Th17 responses and restrains IL-17-mediated skin inflammation. J Autoimmun. 2015;61:73-80 pubmed publisher

Zhang Y, Feng L, Li L, Wang D, Li C, Sun C, et al. Effects of the fusion design and immunization route on the immunogenicity of Ag85A-Mtb32 in adenoviral vectored tuberculosis vaccine. Hum Vaccin Immunother. 2015;11:1803-13 pubmed publisher

Wu X, Dou Y, Yang Y, Bian D, Luo J, Tong B, et al. Arctigenin exerts anti-colitis efficacy through inhibiting the differentiation of Th1 and Th17 cells via an mTORC1-dependent pathway. Biochem Pharmacol. 2015;96:323-36 pubmed publisher

Martin Gayo E, Buzón M, Ouyang Z, Hickman T, Cronin J, Pimenova D, et al. Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers. PLoS Pathog. 2015;11:e1004930 pubmed publisher

Deppisch N, Ruf P, Eissler N, Neff F, Buhmann R, Lindhofer H, et al. Efficacy and Tolerability of a GD2-Directed Trifunctional Bispecific Antibody in a Preclinical Model: Subcutaneous Administration Is Superior to Intravenous Delivery. Mol Cancer Ther. 2015;14:1877-83 pubmed publisher

Wen S, Schuster J, Gilchuk P, Boyd K, Joyce S, Williams J. Lung CD8+ T Cell Impairment Occurs during Human Metapneumovirus Infection despite Virus-Like Particle Induction of Functional CD8+ T Cells. J Virol. 2015;89:8713-26 pubmed publisher

Sakala I, Kjer Nielsen L, Eickhoff C, Wang X, Blazevic A, Liu L, et al. Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites. J Immunol. 2015;195:587-601 pubmed publisher

Basdeo S, Moran B, Cluxton D, Canavan M, McCormick J, Connolly M, et al. Polyfunctional, Pathogenic CD161+ Th17 Lineage Cells Are Resistant to Regulatory T Cell-Mediated Suppression in the Context of Autoimmunity. J Immunol. 2015;195:528-40 pubmed publisher

Erlandson K, Allshouse A, Rapaport E, Palmer B, Wilson C, Weinberg A, et al. Physical function impairment of older, HIV-infected adults is associated with cytomegalovirus immunoglobulin response. AIDS Res Hum Retroviruses. 2015;31:905-12 pubmed publisher

Natividad J, Pinto Sánchez M, Galipeau H, Jury J, Jordana M, Reinisch W, et al. Ecobiotherapy Rich in Firmicutes Decreases Susceptibility to Colitis in a Humanized Gnotobiotic Mouse Model. Inflamm Bowel Dis. 2015;21:1883-93 pubmed publisher

Hsu P, Wu C, Shen S, Yang Y. The role of tomatine adjuvant in antigen delivery for cross- presentation. Curr Drug Deliv. 2015;12:342-50 pubmed

Kallert S, Zenk S, Walther P, Grieshober M, Weil T, Stenger S. Liposomal delivery of lipoarabinomannan triggers Mycobacterium tuberculosis specific T-cells. Tuberculosis (Edinb). 2015;95:452-62 pubmed publisher

Oliveira F, Rowton E, Aslan H, Gomes R, Castrovinci P, Alvarenga P, et al. A sand fly salivary protein vaccine shows efficacy against vector-transmitted cutaneous leishmaniasis in nonhuman primates. Sci Transl Med. 2015;7:290ra90 pubmed publisher

Fénéant L, Potel J, François C, Sané F, Douam F, Belouzard S, et al. New Insights into the Understanding of Hepatitis C Virus Entry and Cell-to-Cell Transmission by Using the Ionophore Monensin A. J Virol. 2015;89:8346-64 pubmed publisher

Carvalheiro T, Gomes D, Pinto L, Inês L, Lopes A, Henriques A, et al. Sera from patients with active systemic lupus erythematosus patients enhance the toll-like receptor 4 response in monocyte subsets. J Inflamm (Lond). 2015;12:38 pubmed publisher

Müller C, Tufa D, Chatterjee D, Muhlradt P, Schmidt R, Jacobs R. The TLR-2/TLR-6 agonist macrophage-activating lipopeptide-2 augments human NK cell cytotoxicity when PGE2 production by monocytes is inhibited by a COX-2 blocker. Cancer Immunol Immunother. 2015;64:1175-84 pubmed publisher

Echeverría A, Moro García M, Asensi V, Cartón J, López Larrea C, Alonso Arias R. CD4⁺CD28null T lymphocytes resemble CD8⁺CD28null T lymphocytes in their responses to IL-15 and IL-21 in HIV-infected patients. J Leukoc Biol. 2015;98:373-84 pubmed publisher

Delfan M, Ebrahim K, Baesi F, Mirakhori Z, Ghalamfarsa G, Bakhshaei P, et al. The immunomodulatory effects of fish-oil supplementation in elite paddlers: A pilot randomized double blind placebo-controlled trial. Prostaglandins Leukot Essent Fatty Acids. 2015;99:35-40 pubmed publisher

Dey M, Chang A, Miska J, Wainwright D, Ahmed A, Balyasnikova I, et al. Dendritic Cell-Based Vaccines that Utilize Myeloid Rather than Plasmacytoid Cells Offer a Superior Survival Advantage in Malignant Glioma. J Immunol. 2015;195:367-76 pubmed publisher

Franz D, Contreras F, González H, Prado C, Elgueta D, Figueroa C, et al. Dopamine receptors D3 and D5 regulate CD4(+)T-cell activation and differentiation by modulating ERK activation and cAMP production. J Neuroimmunol. 2015;284:18-29 pubmed publisher

Santone M, Aprea S, Wu T, Cooke M, Mbow M, Valiante N, et al. A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells. Hum Vaccin Immunother. 2015;11:2038-50 pubmed publisher

Yi H, Eun H, Lee Y, Jung J, Park S, Park K, et al. Treatment with 4-methylpyrazole modulated stellate cells and natural killer cells and ameliorated liver fibrosis in mice. PLoS ONE. 2015;10:e0127946 pubmed publisher

Wang X, Wang Q, Zhang X, Li Y, Wang J, Hou C, et al. Endotoxic shock-expanded murine CD11c low CD45RB + regulatory dendritic cells modulate inflammatory T cell responses through multiple mechanisms. Sci Rep. 2015;5:10653 pubmed publisher

Ritzel R, Patel A, Grenier J, Crapser J, Verma R, Jellison E, et al. Functional differences between microglia and monocytes after ischemic stroke. J Neuroinflammation. 2015;12:106 pubmed publisher

Panackal A, Wuest S, Lin Y, Wu T, Zhang N, Kosa P, et al. Paradoxical Immune Responses in Non-HIV Cryptococcal Meningitis. PLoS Pathog. 2015;11:e1004884 pubmed publisher

Morias Y, Abels C, Laoui D, Van Overmeire E, Guilliams M, Schouppe E, et al. Ly6C- Monocytes Regulate Parasite-Induced Liver Inflammation by Inducing the Differentiation of Pathogenic Ly6C+ Monocytes into Macrophages. PLoS Pathog. 2015;11:e1004873 pubmed publisher

Liu S, Luo J, Liu Y, Tang S, Chen C, Cai H, et al. CD4(+) Foxp3(+) regulatory T-cell number increases in the gastric tissue of C57BL/6 mice infected with Helicobacter pylori. APMIS. 2015;123:571-9 pubmed publisher

Wagage S, Harms Pritchard G, Dawson L, Buza E, Sonnenberg G, Hunter C. The Group 3 Innate Lymphoid Cell Defect in Aryl Hydrocarbon Receptor Deficient Mice Is Associated with T Cell Hyperactivation during Intestinal Infection. PLoS ONE. 2015;10:e0128335 pubmed publisher

Zhu X, Liu J, Feng Y, Pang W, Qi Z, Jiang Y, et al. Phenylhydrazine administration accelerates the development of experimental cerebral malaria. Exp Parasitol. 2015;156:1-11 pubmed publisher

Fougeron D, Van Maele L, Songhet P, Cayet D, Hot D, Van Rooijen N, et al. Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract. Vaccine. 2015;33:3331-41 pubmed publisher

Ross E, Smallie T, Ding Q, O Neil J, Cunliffe H, Tang T, et al. Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin. J Immunol. 2015;195:265-76 pubmed publisher

Lagrue K, Carisey A, Morgan D, Chopra R, Davis D. Lenalidomide augments actin remodeling and lowers NK-cell activation thresholds. Blood. 2015;126:50-60 pubmed publisher

Vigano S, Negron J, Ouyang Z, Rosenberg E, Walker B, Lichterfeld M, et al. Prolonged Antiretroviral Therapy Preserves HIV-1-Specific CD8 T Cells with Stem Cell-Like Properties. J Virol. 2015;89:7829-40 pubmed publisher

Freeman B, Raué H, Hill A, Slifka M. Cytokine-Mediated Activation of NK Cells during Viral Infection. J Virol. 2015;89:7922-31 pubmed publisher

Wu W, Dietze K, Gibbert K, Lang K, Trilling M, Yan H, et al. TLR ligand induced IL-6 counter-regulates the anti-viral CD8(+) T cell response during an acute retrovirus infection. Sci Rep. 2015;5:10501 pubmed publisher

Oxford K, Dela Pena Ponce M, Jensen K, Eberhardt M, Spinner A, Van Rompay K, et al. The interplay between immune maturation, age, chronic viral infection and environment. Immun Ageing. 2015;12:3 pubmed publisher

Jacob C, Yu N, Sindhava V, Cancro M, Pawar R, Putterman C, et al. Differential Development of Systemic Lupus Erythematosus in NZM 2328 Mice Deficient in Discrete Pairs of BAFF Receptors. Arthritis Rheumatol. 2015;67:2523-35 pubmed publisher

Chen Y, Huang Z, Ma D, Chen L, Lai Q, Huang X, et al. Involvement of soluble scavenger receptor A in suppression of T cell activation in patients with chronic hepatitis B. BMC Immunol. 2015;16:29 pubmed publisher

Xue J, Sharma V, Hsieh M, Chawla A, Murali R, Pandol S, et al. Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis. Nat Commun. 2015;6:7158 pubmed publisher

Condotta S, Khan S, Rai D, Griffith T, Badovinac V. Polymicrobial Sepsis Increases Susceptibility to Chronic Viral Infection and Exacerbates CD8+ T Cell Exhaustion. J Immunol. 2015;195:116-25 pubmed publisher

Kumar J, Steele I, Moore A, Murugesan S, Rakonczay Z, Venglovecz V, et al. Gastrin stimulates MMP-1 expression in gastric epithelial cells: putative role in gastric epithelial cell migration. Am J Physiol Gastrointest Liver Physiol. 2015;309:G78-86 pubmed publisher

Long X, Yu Y, Perlaky L, Man T, Redell M. Stromal CYR61 Confers Resistance to Mitoxantrone via Spleen Tyrosine Kinase Activation in Human Acute Myeloid Leukaemia. Br J Haematol. 2015;170:704-18 pubmed publisher

Ilinykh P, Lubaki N, Widen S, Renn L, Theisen T, Rabin R, et al. Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells. J Virol. 2015;89:7567-83 pubmed publisher

Liu Y, Bezverbnaya K, Zhao T, Parsons M, Shi M, Treanor B, et al. Involvement of the HCK and FGR src-family kinases in FCRL4-mediated immune regulation. J Immunol. 2015;194:5851-60 pubmed publisher

Yamashita Kanemaru Y, Takahashi Y, Wang Y, Tahara Hanaoka S, Honda S, Bernhardt G, et al. CD155 (PVR/Necl5) mediates a costimulatory signal in CD4+ T cells and regulates allergic inflammation. J Immunol. 2015;194:5644-53 pubmed publisher

Kang B, Park H, Yum H, Park S, Park J, Kang E, et al. Thymic low affinity/avidity interaction selects natural Th1 cells. J Immunol. 2015;194:5861-71 pubmed publisher

Kato Nagaoka N, Shimada S, Yamakawa Y, Tsujibe S, Naito T, Setoyama H, et al. Enhanced differentiation of intraepithelial lymphocytes in the intestine of polymeric immunoglobulin receptor-deficient mice. Immunology. 2015;146:59-69 pubmed publisher

Chu P, Ebinuma H, Nakamoto N, Sugiyama K, Usui S, Wakayama Y, et al. Genotype-Associated Differential NKG2D Expression on CD56+CD3+ Lymphocytes Predicts Response to Pegylated-Interferon/Ribavirin Therapy in Chronic Hepatitis C. PLoS ONE. 2015;10:e0125664 pubmed publisher

Hünemörder S, Treder J, Ahrens S, Schumacher V, Paust H, Menter T, et al. TH1 and TH17 cells promote crescent formation in experimental autoimmune glomerulonephritis. J Pathol. 2015;237:62-71 pubmed publisher

Yang L, Carrillo M, Wu Y, DiAngelo S, Silveyra P, Umstead T, et al. SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation. PLoS ONE. 2015;10:e0126576 pubmed publisher

Gertel S, Serre G, Shoenfeld Y, Amital H. Immune tolerance induction with multiepitope peptide derived from citrullinated autoantigens attenuates arthritis manifestations in adjuvant arthritis rats. J Immunol. 2015;194:5674-80 pubmed publisher

Zhang Z, Wang L, Luo Z, Zhao X, Huang J, Li H, et al. Efficacy and safety of cord blood-derived cytokine-induced killer cells in treatment of patients with malignancies. Cytotherapy. 2015;17:1130-8 pubmed publisher

Pan W, Zhu S, Dai D, Liu Z, Li D, Li B, et al. MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis. Nat Commun. 2015;6:7096 pubmed publisher

Patel P, Kearney J. Neonatal exposure to pneumococcal phosphorylcholine modulates the development of house dust mite allergy during adult life. J Immunol. 2015;194:5838-50 pubmed publisher

Schneider U, Davids A, Brandenburg S, Müller A, Elke A, Magrini S, et al. Microglia inflict delayed brain injury after subarachnoid hemorrhage. Acta Neuropathol. 2015;130:215-31 pubmed publisher

Liberal R, Grant C, Holder B, Cardone J, Martinez Llordella M, Ma Y, et al. In autoimmune hepatitis type 1 or the autoimmune hepatitis-sclerosing cholangitis variant defective regulatory T-cell responsiveness to IL-2 results in low IL-10 production and impaired suppression. Hepatology. 2015;62:863-75 pubmed publisher

Martinet V, Tonon S, Torres D, Azouz A, Nguyen M, Kohler A, et al. Type I interferons regulate eomesodermin expression and the development of unconventional memory CD8(+) T cells. Nat Commun. 2015;6:7089 pubmed publisher

Deutsch M, Graffeo C, Rokosh R, Pansari M, Ochi A, Levie E, et al. Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury. Cell Death Dis. 2015;6:e1759 pubmed publisher

Wang S, Li Y, Piao H, Hong X, Zhang D, Xu Y, et al. PD-1 and Tim-3 pathways are associated with regulatory CD8+ T-cell function in decidua and maintenance of normal pregnancy. Cell Death Dis. 2015;6:e1738 pubmed publisher

Partlová S, Bouček J, Kloudová K, Lukešová E, Zábrodský M, Grega M, et al. Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma. Oncoimmunology. 2015;4:e965570 pubmed

Lhuillier C, Barjon C, Niki T, Gelin A, Praz F, Morales O, et al. Impact of Exogenous Galectin-9 on Human T Cells: CONTRIBUTION OF THE T CELL RECEPTOR COMPLEX TO ANTIGEN-INDEPENDENT ACTIVATION BUT NOT TO APOPTOSIS INDUCTION. J Biol Chem. 2015;290:16797-811 pubmed publisher

Boer M, Prins C, van Meijgaarden K, van Dissel J, Ottenhoff T, Joosten S. Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults. Clin Vaccine Immunol. 2015;22:778-88 pubmed publisher

Chai J, Ratnasothy K, Bucy R, Noelle R, Lechler R, Lombardi G. Allospecific CD4(+) T cells retain effector function and are actively regulated by Treg cells in the context of transplantation tolerance. Eur J Immunol. 2015;45:2017-27 pubmed publisher

Pan D, Lin Y, Wu W, Song J, Zhang E, Wu C, et al. Persistence of the recombinant genomes of woodchuck hepatitis virus in the mouse model. PLoS ONE. 2015;10:e0125658 pubmed publisher

Bae J, Samur M, Munshi A, Hideshima T, Keskin D, Kimmelman A, et al. Heteroclitic XBP1 peptides evoke tumor-specific memory cytotoxic T lymphocytes against breast cancer, colon cancer, and pancreatic cancer cells. Oncoimmunology. 2014;3:e970914 pubmed

Verinaud L, Lopes S, Prado I, Zanucoli F, Alves da Costa T, Di Gangi R, et al. Violacein Treatment Modulates Acute and Chronic Inflammation through the Suppression of Cytokine Production and Induction of Regulatory T Cells. PLoS ONE. 2015;10:e0125409 pubmed publisher

Lee J, Jeong I, Joh J, Jung Y, Sim S, Choi B, et al. Differential expression of CD57 in antigen-reactive CD4+ T cells between active and latent tuberculosis infection. Clin Immunol. 2015;159:37-46 pubmed publisher

Riccio E, Pratt Riccio L, Bianco Júnior C, Sanchez V, Totino P, Carvalho L, et al. Molecular and immunological tools for the evaluation of the cellular immune response in the neotropical monkey Saimiri sciureus, a non-human primate model for malaria research. Malar J. 2015;14:166 pubmed publisher

Ortutay Z, Oksanen A, Aittomäki S, Ortutay C, Pesu M. Proprotein convertase FURIN regulates T cell receptor-induced transactivation. J Leukoc Biol. 2015;98:73-83 pubmed publisher

Ayinde D, Bruel T, Cardinaud S, Porrot F, Prado J, Moris A, et al. SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells. J Virol. 2015;89:6994-7006 pubmed

Hanley P, Melenhorst J, Nikiforow S, Scheinberg P, Blaney J, Demmler Harrison G, et al. CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo. Sci Transl Med. 2015;7:285ra63 pubmed publisher

Lenz N, Schindler T, Kagina B, Zhang J, Lukindo T, Mpina M, et al. Antiviral Innate Immune Activation in HIV-Infected Adults Negatively Affects H1/IC31-Induced Vaccine-Specific Memory CD4+ T Cells. Clin Vaccine Immunol. 2015;22:688-96 pubmed publisher

Song Z, Yamasaki R, Kawano Y, Sato S, Masaki K, Yoshimura S, et al. Peripheral blood T cell dynamics predict relapse in multiple sclerosis patients on fingolimod. PLoS ONE. 2014;10:e0124923 pubmed publisher

Sun Y, Deng W, Geng L, Zhang L, Liu R, Chen W, et al. Mesenchymal stem cells from patients with rheumatoid arthritis display impaired function in inhibiting Th17 cells. J Immunol Res. 2015;2015:284215 pubmed publisher

Moguche A, Shafiani S, Clemons C, Larson R, Dinh C, Higdon L, et al. ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis. J Exp Med. 2015;212:715-28 pubmed publisher

Becker P, Hervouet C, Mason G, KWON S, Klavinskis L. Skin vaccination with live virus vectored microneedle arrays induce long lived CD8(+) T cell memory. Vaccine. 2015;33:4691-8 pubmed publisher

Krementsov D, Case L, Hickey W, Teuscher C. Exacerbation of autoimmune neuroinflammation by dietary sodium is genetically controlled and sex specific. FASEB J. 2015;29:3446-57 pubmed publisher

Reis B, Lee K, Fanok M, Mascaraque C, Amoury M, Cohn L, et al. Leptin receptor signaling in T cells is required for Th17 differentiation. J Immunol. 2015;194:5253-60 pubmed publisher

Dahlgren M, Gustafsson Hedberg T, Livingston M, Cucak H, Alsén S, Yrlid U, et al. T follicular helper, but not Th1, cell differentiation in the absence of conventional dendritic cells. J Immunol. 2015;194:5187-99 pubmed publisher

Litjens N, Boer K, Zuijderwijk J, Klepper M, Peeters A, Prens E, et al. Allogeneic Mature Human Dendritic Cells Generate Superior Alloreactive Regulatory T Cells in the Presence of IL-15. J Immunol. 2015;194:5282-93 pubmed publisher

Schmueck Henneresse M, Sharaf R, Vogt K, Weist B, Landwehr Kenzel S, Fuehrer H, et al. Peripheral blood-derived virus-specific memory stem T cells mature to functional effector memory subsets with self-renewal potency. J Immunol. 2015;194:5559-67 pubmed publisher

Bioley G, Lassus A, Terrettaz J, Tranquart F, Corthésy B. Long-term persistence of immunity induced by OVA-coupled gas-filled microbubble vaccination partially protects mice against infection by OVA-expressing Listeria. Biomaterials. 2015;57:153-60 pubmed publisher

Deng Z, Mu J, Tseng M, Wattenberg B, Zhuang X, Egilmez N, et al. Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis. Nat Commun. 2015;6:6956 pubmed publisher

Teng X, Tian M, Li J, Tan S, Yuan X, Yu Q, et al. Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine. Hum Vaccin Immunother. 2015;11:1456-64 pubmed publisher

Quan C, ZhangBao J, Lu J, Zhao C, Cai T, Wang B, et al. The immune balance between memory and regulatory B cells in NMO and the changes of the balance after methylprednisolone or rituximab therapy. J Neuroimmunol. 2015;282:45-53 pubmed publisher

Meyer C, Walker J, Dewane J, Engelmann F, Laub W, Pillai S, et al. Impact of irradiation and immunosuppressive agents on immune system homeostasis in rhesus macaques. Clin Exp Immunol. 2015;181:491-510 pubmed publisher

Yang J, Li Q, Yang X, Li M. Interleukin-9 Is Associated with Elevated Anti-Double-Stranded DNA Antibodies in Lupus-Prone Mice. Mol Med. 2015;21:364-70 pubmed publisher

Zhao K, Murray E, Murray S. Fibroblastic synoviocytes secrete plasma proteins via α2 -macroglobulins serving as intracellular and extracellular chaperones. J Cell Biochem. 2015;116:2563-76 pubmed publisher

Declercq V, d Eon B, McLeod R. Fatty acids increase adiponectin secretion through both classical and exosome pathways. Biochim Biophys Acta. 2015;1851:1123-33 pubmed publisher

Maeda K, Kosugi T, Sato W, Kojima H, Sato Y, Kamimura D, et al. CD147/basigin limits lupus nephritis and Th17 cell differentiation in mice by inhibiting the interleukin-6/STAT-3 pathway. Arthritis Rheumatol. 2015;67:2185-95 pubmed publisher

Amico D, Spadoni T, Rovinelli M, Serafini M, D Amico G, Campelli N, et al. Intracellular free radical production by peripheral blood T lymphocytes from patients with systemic sclerosis: role of NADPH oxidase and ERK1/2. Arthritis Res Ther. 2015;17:68 pubmed publisher

Bijker E, Nganou Makamdop K, van Gemert G, Zavala F, Cockburn I, Sauerwein R. Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria. Malar J. 2015;14:130 pubmed publisher

Otero D, Fares Frederickson N, Xiao M, Baker D, David M. IFN-β Selectively Inhibits IL-2 Production through CREM-Mediated Chromatin Remodeling. J Immunol. 2015;194:5120-8 pubmed publisher

Cieslik K, Trial J, Entman M. Mesenchymal stem cell-derived inflammatory fibroblasts promote monocyte transition into myeloid fibroblasts via an IL-6-dependent mechanism in the aging mouse heart. FASEB J. 2015;29:3160-70 pubmed publisher

Sartorius R, D Apice L, Trovato M, Cuccaro F, Costa V, De Leo M, et al. Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response. EMBO Mol Med. 2015;7:973-88 pubmed publisher

Chang C, Liou J. Phosphatidylinositol 4,5-Bisphosphate Homeostasis Regulated by Nir2 and Nir3 Proteins at Endoplasmic Reticulum-Plasma Membrane Junctions. J Biol Chem. 2015;290:14289-301 pubmed publisher

Pombo C, Wherry E, Gostick E, Price D, Betts M. Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers. J Infect Dis. 2015;212:1376-86 pubmed publisher

Costa Pereira C, Moreira M, Soares R, Marteleto B, Ribeiro V, França Dias M, et al. One-year timeline kinetics of cytokine-mediated cellular immunity in dogs vaccinated against visceral leishmaniasis. BMC Vet Res. 2015;11:92 pubmed publisher

Maggioli M, Palmer M, Thacker T, Vordermeier H, Waters W. Characterization of effector and memory T cell subsets in the immune response to bovine tuberculosis in cattle. PLoS ONE. 2015;10:e0122571 pubmed publisher

Liu Z, Kan Y, Wei Y, Li X, Yang F, Hou Y, et al. Decreased number of CD14+TLR4+ monocytes and their impaired cytokine responses to lipopolysaccharide in patients with chronic kidney disease. J Huazhong Univ Sci Technolog Med Sci. 2015;35:206-211 pubmed publisher

Munseri P, Kroidl A, Nilsson C, Joachim A, Geldmacher C, Mann P, et al. Priming with a simplified intradermal HIV-1 DNA vaccine regimen followed by boosting with recombinant HIV-1 MVA vaccine is safe and immunogenic: a phase IIa randomized clinical trial. PLoS ONE. 2015;10:e0119629 pubmed publisher

Bächle S, Sauter D, Sibitz S, Sandberg J, Kirchhoff F, Moll M. Involvement of a C-terminal motif in the interference of primate lentiviral Vpu proteins with CD1d-mediated antigen presentation. Sci Rep. 2015;5:9675 pubmed publisher

Blanco B, Herrero Sánchez M, Rodríguez Serrano C, Sánchez Barba M, Del Cañizo M. Profound blockade of T cell activation requires concomitant inhibition of different class I PI3K isoforms. Immunol Res. 2015;62:175-88 pubmed publisher

Aurisicchio L, Roscilli G, Marra E, Luberto L, Mancini R, La Monica N, et al. Superior Immunologic and Therapeutic Efficacy of a Xenogeneic Genetic Cancer Vaccine Targeting Carcinoembryonic Human Antigen. Hum Gene Ther. 2015;26:386-98 pubmed publisher

Rajavelu P, Chen G, Xu Y, Kitzmiller J, Korfhagen T, Whitsett J. Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation. J Clin Invest. 2015;125:2021-31 pubmed publisher

Spiering R, Margry B, Keijzer C, Petzold C, Hoek A, Wagenaar Hilbers J, et al. DEC205+ Dendritic Cell-Targeted Tolerogenic Vaccination Promotes Immune Tolerance in Experimental Autoimmune Arthritis. J Immunol. 2015;194:4804-13 pubmed publisher

Geldenhuys H, Mearns H, Foster J, Saxon E, Kagina B, Saganic L, et al. A randomized clinical trial in adults and newborns in South Africa to compare the safety and immunogenicity of bacille Calmette-Guérin (BCG) vaccine administration via a disposable-syringe jet injector to conventional technique with needle and syring. Vaccine. 2015;33:4719-26 pubmed publisher

Lorin C, Vanloubbeeck Y, Baudart S, Ska M, Bayat B, Brauers G, et al. Heterologous prime-boost regimens with a recombinant chimpanzee adenoviral vector and adjuvanted F4 protein elicit polyfunctional HIV-1-specific T-Cell responses in macaques. PLoS ONE. 2015;10:e0122835 pubmed publisher

Kageyama S, Ikeda H, Miyahara Y, Imai N, Ishihara M, Saito K, et al. Adoptive Transfer of MAGE-A4 T-cell Receptor Gene-Transduced Lymphocytes in Patients with Recurrent Esophageal Cancer. Clin Cancer Res. 2015;21:2268-77 pubmed publisher

Zellweger R, Tang W, Eddy W, King K, Sanchez M, Shresta S. CD8+ T Cells Can Mediate Short-Term Protection against Heterotypic Dengue Virus Reinfection in Mice. J Virol. 2015;89:6494-505 pubmed publisher

Rist M, Hibbert K, Croft N, Smith C, Neller M, Burrows J, et al. T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells. J Immunol. 2015;194:4668-75 pubmed publisher

Nielsen C, White M, Bottomley C, Lusa C, Rodríguez Galán A, Turner S, et al. Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals. J Immunol. 2015;194:4657-67 pubmed publisher

Kato S, Chen J, Cornog K, Zhang H, Roberts J. The Golgi apparatus regulates cGMP-dependent protein kinase I compartmentation and proteolysis. Am J Physiol Cell Physiol. 2015;308:C944-58 pubmed publisher

Hussaarts L, García Tardón N, van Beek L, Heemskerk M, Haeberlein S, van der Zon G, et al. Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice. FASEB J. 2015;29:3027-39 pubmed publisher

Rahman M, Sobia P, Dwivedi V, Bhawsar A, Singh D, Sharma P, et al. Mycobacterium tuberculosis TlyA Protein Negatively Regulates T Helper (Th) 1 and Th17 Differentiation and Promotes Tuberculosis Pathogenesis. J Biol Chem. 2015;290:14407-17 pubmed publisher

Zhao X, Zhang Z, Li H, Huang J, Yang S, Xie T, et al. Cytokine induced killer cell-based immunotherapies in patients with different stages of renal cell carcinoma. Cancer Lett. 2015;362:192-8 pubmed publisher

Wang X, Wong C, Urak R, Mardiros A, Budde L, Chang W, et al. CMVpp65 Vaccine Enhances the Antitumor Efficacy of Adoptively Transferred CD19-Redirected CMV-Specific T Cells. Clin Cancer Res. 2015;21:2993-3002 pubmed publisher

Bendezú F, Vincenzetti V, Vavylonis D, Wyss R, Vogel H, Martin S. Spontaneous Cdc42 polarization independent of GDI-mediated extraction and actin-based trafficking. PLoS Biol. 2015;13:e1002097 pubmed publisher

Kwon Y, Cho Y, Kim M, Jin H, Jung H, Kang J, et al. Mucosal-associated invariant T cells are numerically and functionally deficient in patients with mycobacterial infection and reflect disease activity. Tuberculosis (Edinb). 2015;95:267-74 pubmed publisher

Schönberg K, Rudolph J, Vonnahme M, Parampalli Yajnanarayana S, Cornez I, Hejazi M, et al. JAK Inhibition Impairs NK Cell Function in Myeloproliferative Neoplasms. Cancer Res. 2015;75:2187-99 pubmed publisher

Xu Y, Lin J, Bian M, Chen W, Liang P, Wang X, et al. CsRNASET2 is an important component of Clonorchis sinensis responsible for eliciting Th2 immune response. Parasitol Res. 2015;114:2371-9 pubmed publisher

Wang J, Shirota Y, Bayık D, Shirota H, Tross D, Gulley J, et al. Effect of TLR agonists on the differentiation and function of human monocytic myeloid-derived suppressor cells. J Immunol. 2015;194:4215-21 pubmed publisher

Clements D, Sterea A, Kim Y, Helson E, Dean C, Nunokawa A, et al. Newly recruited CD11b+, GR-1+, Ly6C(high) myeloid cells augment tumor-associated immunosuppression immediately following the therapeutic administration of oncolytic reovirus. J Immunol. 2015;194:4397-412 pubmed publisher

Moussa M, Arrode Brusés G, Manoylov I, Malogolovkin A, Mompelat D, Ishimwe H, et al. A novel non-integrative single-cycle chimeric HIV lentivector DNA vaccine. Vaccine. 2015;33:2273-2282 pubmed publisher

Wisniewski J, Commins S, Agrawal R, Hulse K, Yu M, Cronin J, et al. Analysis of cytokine production by peanut-reactive T cells identifies residual Th2 effectors in highly allergic children who received peanut oral immunotherapy. Clin Exp Allergy. 2015;45:1201-13 pubmed publisher

Marsh A, Ambagala A, Perciani C, Russell J, Chan J, Janes M, et al. Examining the species-specificity of rhesus macaque cytomegalovirus (RhCMV) in cynomolgus macaques. PLoS ONE. 2015;10:e0121339 pubmed publisher

Vassena L, Giuliani E, Koppensteiner H, Bolduan S, Schindler M, Doria M. HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes. J Virol. 2015;89:5687-700 pubmed publisher

Adekambi T, Ibegbu C, Cagle S, Kalokhe A, Wang Y, Hu Y, et al. Biomarkers on patient T cells diagnose active tuberculosis and monitor treatment response. J Clin Invest. 2015;125:1827-38 pubmed publisher

Shui B, Xia W, Wen C, Ding X. Jieduquyuziyin prescription suppresses IL-17 production and Th17 activity in MRL/lpr mice by inhibiting expression of Ca(2+)/calmodulin-dependent protein kinase-4. J Nat Med. 2015;69:349-57 pubmed publisher

Dixon K, van der Kooij S, Vignali D, van Kooten C. Human tolerogenic dendritic cells produce IL-35 in the absence of other IL-12 family members. Eur J Immunol. 2015;45:1736-47 pubmed publisher

Aps L, Diniz M, Porchia B, Sales N, Moreno A, Ferreira L. Bacillus subtilis spores as adjuvants for DNA vaccines. Vaccine. 2015;33:2328-34 pubmed publisher

Skrindo I, Ballke C, Gran E, Johansen F, Baekkevold E, Jahnsen F. IL-5 production by resident mucosal allergen-specific T cells in an explant model of allergic rhinitis. Clin Exp Allergy. 2015;45:1296-304 pubmed publisher

Brezar V, Ruffin N, Richert L, Surenaud M, Lacabaratz C, Palucka K, et al. Decreased HIV-specific T-regulatory responses are associated with effective DC-vaccine induced immunity. PLoS Pathog. 2015;11:e1004752 pubmed publisher

Parrish C, Scott G, Migneco G, Scott K, Steele L, Ilett E, et al. Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia. Leukemia. 2015;29:1799-810 pubmed publisher

Pritzl C, Seo Y, Xia C, Vijayan M, Stokes Z, Hahm B. A ceramide analogue stimulates dendritic cells to promote T cell responses upon virus infections. J Immunol. 2015;194:4339-49 pubmed publisher

Bet A, Maze E, Bansal A, Sterrett S, Gross A, Graff Dubois S, et al. The HIV-1 antisense protein (ASP) induces CD8 T cell responses during chronic infection. Retrovirology. 2015;12:15 pubmed publisher

Hong M, Sandalova E, Low D, Gehring A, Fieni S, Amadei B, et al. Trained immunity in newborn infants of HBV-infected mothers. Nat Commun. 2015;6:6588 pubmed publisher

Marin M, Yawn B, Hales C, Wollan P, Bialek S, Zhang J, et al. Herpes zoster vaccine effectiveness and manifestations of herpes zoster and associated pain by vaccination status. Hum Vaccin Immunother. 2015;11:1157-64 pubmed publisher

Sanders K, Fox B, Bzik D. Attenuated Toxoplasma gondii Stimulates Immunity to Pancreatic Cancer by Manipulation of Myeloid Cell Populations. Cancer Immunol Res. 2015;3:891-901 pubmed publisher

Talukdar A, Sharma K, Rai R, Deka D, Rao D. Effect of Coenzyme Q10 on Th1/Th2 Paradigm in Females with Idiopathic Recurrent Pregnancy Loss. Am J Reprod Immunol. 2015;74:169-80 pubmed publisher

McClanahan F, Hanna B, Miller S, Clear A, Lichter P, Gribben J, et al. PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia. Blood. 2015;126:203-11 pubmed publisher

Stepanova L, Kotlyarov R, Kovaleva A, Potapchuk M, Korotkov A, Sergeeva M, et al. Protection against multiple influenza A virus strains induced by candidate recombinant vaccine based on heterologous M2e peptides linked to flagellin. PLoS ONE. 2015;10:e0119520 pubmed publisher

Golden Mason L, Waasdorp Hurtado C, Cheng L, Rosen H. Hepatitis C viral infection is associated with activated cytolytic natural killer cells expressing high levels of T cell immunoglobulin- and mucin-domain-containing molecule-3. Clin Immunol. 2015;158:114-25 pubmed publisher

Gutierrez Hincapié S, Muskus López C, Montoya C, Trujillo Vargas C. Quantitative defects in invariant NKT cells and TLR responses in patients with hyper-IgE syndrome. Allergol Immunopathol (Madr). 2015;43:553-61 pubmed publisher

Srivastava P, Paluch B, Matsuzaki J, James S, Collamat Lai G, Taverna P, et al. Immunomodulatory action of the DNA methyltransferase inhibitor SGI-110 in epithelial ovarian cancer cells and xenografts. Epigenetics. 2015;10:237-46 pubmed publisher

Watanabe R, Gehad A, Yang C, Scott L, Teague J, Schlapbach C, et al. Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells. Sci Transl Med. 2015;7:279ra39 pubmed publisher

Larena M, Holmgren J, Lebens M, Terrinoni M, Lundgren A. Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic AMP-protein kinase A and inflammasome-dependent IL-1 signaling. J Immunol. 2015;194:3829-39 pubmed publisher

Kim H, Kim A, Kim D, Kim H, Park Y, Jang G, et al. Interleukin-10-producing CD5+ B cells inhibit mast cells during immunoglobulin E-mediated allergic responses. Sci Signal. 2015;8:ra28 pubmed publisher

Kaltenmeier C, Gawanbacht A, Beyer T, Lindner S, Trzaska T, van der Merwe J, et al. CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients. J Immunol. 2015;194:3768-77 pubmed publisher

Rubio Infante N, Govea Alonso D, Romero Maldonado A, García Hernández A, Ilhuicatzi Alvarado D, Salazar Gonzalez J, et al. A Plant-Derived Multi-HIV Antigen Induces Broad Immune Responses in Orally Immunized Mice. Mol Biotechnol. 2015;57:662-74 pubmed publisher

Odobasic D, Muljadi R, O Sullivan K, Kettle A, Dickerhof N, Summers S, et al. Suppression of Autoimmunity and Renal Disease in Pristane-Induced Lupus by Myeloperoxidase. Arthritis Rheumatol. 2015;67:1868-80 pubmed publisher

Zhang J, Lapato A, Bodhankar S, Vandenbark A, Offner H. Treatment with IL-10 producing B cells in combination with E2 ameliorates EAE severity and decreases CNS inflammation in B cell-deficient mice. Metab Brain Dis. 2015;30:1117-27 pubmed publisher

Mitsopoulos P, Chang Y, Wai T, König T, Dunn S, Langer T, et al. Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function. Mol Cell Biol. 2015;35:1838-47 pubmed publisher

Wang Y, Cao L, Xu L, Cao F, Peng B, Zhang X, et al. Celastrol Ameliorates EAE Induction by Suppressing Pathogenic T Cell Responses in the Peripheral and Central Nervous Systems. J Neuroimmune Pharmacol. 2015;10:506-16 pubmed publisher

Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, et al. Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy. EMBO J. 2015;34:1214-30 pubmed publisher

Cox S, Serino G, Sallustio F, Blasi A, Rossini M, Pesce F, et al. Altered monocyte expression and expansion of non-classical monocyte subset in IgA nephropathy patients. Nephrol Dial Transplant. 2015;30:1122-232 pubmed publisher

Bretscher P, Egger J, Shamshiev A, Trötzmüller M, Köfeler H, Carreira E, et al. Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2. EMBO Mol Med. 2015;7:593-607 pubmed publisher

Knudson C, Hartwig S, Meyerholz D, Varga S. RSV vaccine-enhanced disease is orchestrated by the combined actions of distinct CD4 T cell subsets. PLoS Pathog. 2015;11:e1004757 pubmed publisher

Kim Y, Lim H, Jung H, Wetsel R, Chung Y. Regulation of autoimmune germinal center reactions in lupus-prone BXD2 mice by follicular helper T cells. PLoS ONE. 2015;10:e0120294 pubmed publisher

Stranks A, Hansen A, Panse I, Mortensen M, Ferguson D, Puleston D, et al. Autophagy Controls Acquisition of Aging Features in Macrophages. J Innate Immun. 2015;7:375-91 pubmed publisher

Perez Mazliah D, Ng D, Freitas do Rosario A, McLaughlin S, Mastelic Gavillet B, Sodenkamp J, et al. Disruption of IL-21 signaling affects T cell-B cell interactions and abrogates protective humoral immunity to malaria. PLoS Pathog. 2015;11:e1004715 pubmed publisher

Cedeno Laurent F, Singer E, Wysocka M, Benoit B, Vittorio C, Kim E, et al. Improved pruritus correlates with lower levels of IL-31 in CTCL patients under different therapeutic modalities. Clin Immunol. 2015;158:1-7 pubmed publisher

Nowyhed H, Huynh T, Blatchley A, Wu R, Thomas G, Hedrick C. The nuclear receptor nr4a1 controls CD8 T cell development through transcriptional suppression of runx3. Sci Rep. 2015;5:9059 pubmed publisher

Rivino L, Kumaran E, Thein T, Too C, Gan V, Hanson B, et al. Virus-specific T lymphocytes home to the skin during natural dengue infection. Sci Transl Med. 2015;7:278ra35 pubmed publisher

Aychek T, Mildner A, Yona S, Kim K, Lampl N, Reich Zeliger S, et al. IL-23-mediated mononuclear phagocyte crosstalk protects mice from Citrobacter rodentium-induced colon immunopathology. Nat Commun. 2015;6:6525 pubmed publisher

Hoang T, Agger E, Cassidy J, Christensen J, Andersen P. Protein energy malnutrition during vaccination has limited influence on vaccine efficacy but abolishes immunity if administered during Mycobacterium tuberculosis infection. Infect Immun. 2015;83:2118-26 pubmed publisher

Serti E, Chepa Lotrea X, Kim Y, Keane M, Fryzek N, Liang T, et al. Successful Interferon-Free Therapy of Chronic Hepatitis C Virus Infection Normalizes Natural Killer Cell Function. Gastroenterology. 2015;149:190-200.e2 pubmed publisher

Magalhaes I, Pingris K, Poitou C, Bessoles S, Venteclef N, Kiaf B, et al. Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients. J Clin Invest. 2015;125:1752-62 pubmed publisher

Chaturvedi V, Ertelt J, Jiang T, Kinder J, Xin L, Owens K, et al. CXCR3 blockade protects against Listeria monocytogenes infection-induced fetal wastage. J Clin Invest. 2015;125:1713-25 pubmed publisher

Vogel S, Schlickeiser S, Jürchott K, Akyuez L, Schumann J, Appelt C, et al. TCAIM decreases T cell priming capacity of dendritic cells by inhibiting TLR-induced Ca2+ influx and IL-2 production. J Immunol. 2015;194:3136-46 pubmed publisher

Prado Garcia H, Romero Garcia S, Rumbo Nava U, Lopez Gonzalez J. Predominance of Th17 over regulatory T-cells in pleural effusions of patients with lung cancer implicates a proinflammatory profile. Anticancer Res. 2015;35:1529-35 pubmed

Olsen A, Follmann F, Erneholm K, Rosenkrands I, Andersen P. Protection Against Chlamydia trachomatis Infection and Upper Genital Tract Pathological Changes by Vaccine-Promoted Neutralizing Antibodies Directed to the VD4 of the Major Outer Membrane Protein. J Infect Dis. 2015;212:978-89 pubmed publisher

Gold M, Hughes M, Antignano F, Hirota J, Zaph C, McNagny K. Lineage-specific regulation of allergic airway inflammation by the lipid phosphatase Src homology 2 domain-containing inositol 5-phosphatase (SHIP-1). J Allergy Clin Immunol. 2015;136:725-736.e2 pubmed publisher

Mazzoni A, Santarlasci V, Maggi L, Capone M, Rossi M, Querci V, et al. Demethylation of the RORC2 and IL17A in human CD4+ T lymphocytes defines Th17 origin of nonclassic Th1 cells. J Immunol. 2015;194:3116-26 pubmed publisher

Ishikawa T, Adachi S, Okayama T, Kokura S, Mizushima K, Doi T, et al. Cytotoxic T lymphocyte-associated antigen 4 inhibition increases the antitumor activity of adoptive T-cell therapy when carried out with naïve rather than differentiated T cells. Oncol Rep. 2015;33:2545-52 pubmed publisher

Trondsen M, Aqrawi L, Zhou F, Pedersen G, Trieu M, Zhou P, et al. Induction of Local Secretory IgA and Multifunctional CD4⁺ T-helper Cells Following Intranasal Immunization with a H5N1 Whole Inactivated Influenza Virus Vaccine in BALB/c Mice. Scand J Immunol. 2015;81:305-17 pubmed publisher

Zeeshan M, Tyagi K, Sharma Y. CD4+ T cell response correlates with naturally acquired antibodies against Plasmodium vivax tryptophan-rich antigens. Infect Immun. 2015;83:2018-29 pubmed publisher

Mahne A, Klementowicz J, Chou A, Nguyen V, Tang Q. Therapeutic regulatory T cells subvert effector T cell function in inflamed islets to halt autoimmune diabetes. J Immunol. 2015;194:3147-55 pubmed publisher

Du H, Zhang X, An Y, Ding Y, Zhao X. Effects of Wiskott-Aldrich Syndrome Protein Deficiency on IL-10-Producing Regulatory B Cells in Humans and Mice. Scand J Immunol. 2015;81:483-93 pubmed publisher

van der Waart A, Fredrix H, van der Voort R, Schaap N, Hobo W, Dolstra H. siRNA silencing of PD-1 ligands on dendritic cell vaccines boosts the expansion of minor histocompatibility antigen-specific CD8(+) T cells in NOD/SCID/IL2Rg(null) mice. Cancer Immunol Immunother. 2015;64:645-54 pubmed publisher

Kobayashi K, Tomiki H, Inaba Y, Ichikawa M, Kim B, Koh C. Dimethyl fumarate suppresses Theiler's murine encephalomyelitis virus-induced demyelinating disease by modifying the Nrf2-Keap1 pathway. Int Immunol. 2015;27:333-44 pubmed publisher

Jensen K, Camejo A, Melo M, Cordeiro C, Julien L, Grotenbreg G, et al. Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination. MBio. 2015;6:e02280 pubmed publisher

Warth S, Hoefig K, Hiekel A, Schallenberg S, Jovanovic K, Klein L, et al. Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation. EMBO J. 2015;34:1195-213 pubmed publisher

Amatngalim G, van Wijck Y, de Mooij Eijk Y, Verhoosel R, Harder J, Lekkerkerker A, et al. Basal cells contribute to innate immunity of the airway epithelium through production of the antimicrobial protein RNase 7. J Immunol. 2015;194:3340-50 pubmed publisher

Thapa M, Chinnadurai R, Velazquez V, Tedesco D, Elrod E, Han J, et al. Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity. Hepatology. 2015;61:2067-79 pubmed publisher

Suryawanshi A, Manoharan I, Hong Y, Swafford D, Majumdar T, Taketo M, et al. Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation. J Immunol. 2015;194:3295-304 pubmed publisher

Biswas A, Bruder D, Wolf S, Jeron A, Mack M, Heimesaat M, et al. Ly6C(high) monocytes control cerebral toxoplasmosis. J Immunol. 2015;194:3223-35 pubmed publisher

Ortved K, Wagner B, Calcedo R, Wilson J, Schaefer D, Nixon A. Humoral and cell-mediated immune response, and growth factor synthesis after direct intraarticular injection of rAAV2-IGF-I and rAAV5-IGF-I in the equine middle carpal joint. Hum Gene Ther. 2015;26:161-71 pubmed publisher

Zhao P, Bu X, Wei X, Sun W, Xie X, Li C, et al. Dendritic cell immunotherapy combined with cytokine-induced killer cells promotes skewing toward Th2 cytokine profile in patients with metastatic non-small cell lung cancer. Int Immunopharmacol. 2015;25:450-6 pubmed publisher

Khattar S, Palaniyandi S, Samal S, LaBranche C, Montefiori D, Zhu X, et al. Evaluation of humoral, mucosal, and cellular immune responses following co-immunization of HIV-1 Gag and Env proteins expressed by Newcastle disease virus. Hum Vaccin Immunother. 2015;11:504-15 pubmed publisher

Jobsri J, Allen A, Rajagopal D, Shipton M, Kanyuka K, Lomonossoff G, et al. Plant virus particles carrying tumour antigen activate TLR7 and Induce high levels of protective antibody. PLoS ONE. 2015;10:e0118096 pubmed publisher

Camargo J, Resende M, Zamel R, Klement W, Bhimji A, Huibner S, et al. Potential role of CC chemokine receptor 6 in prediction of late-onset cytomegalovirus infection following solid organ transplant. Clin Transplant. 2015;29:492-8 pubmed publisher

Yasuda D, Imura Y, Ishii S, Shimizu T, Nakamura M. The atypical N-glycosylation motif, Asn-Cys-Cys, in human GPR109A is required for normal cell surface expression and intracellular signaling. FASEB J. 2015;29:2412-22 pubmed publisher

Han D, Walsh M, Kim K, Hong S, Lee J, Yi J, et al. Microbiota-Independent Ameliorative Effects of Antibiotics on Spontaneous Th2-Associated Pathology of the Small Intestine. PLoS ONE. 2015;10:e0118795 pubmed publisher

Dobenecker M, Kim J, Marcello J, Fang T, Prinjha R, Bosselut R, et al. Coupling of T cell receptor specificity to natural killer T cell development by bivalent histone H3 methylation. J Exp Med. 2015;212:297-306 pubmed publisher

Papasavvas E, Foulkes A, Yin X, Joseph J, Ross B, Azzoni L, et al. Plasmacytoid dendritic cell and functional HIV Gag p55-specific T cells before treatment interruption can inform set-point plasma HIV viral load after treatment interruption in chronically suppressed HIV-1(+) patients. Immunology. 2015;145:380-90 pubmed publisher

de Bruyne R, Bogaert D, De Ruyck N, Lambrecht B, Van Winckel M, Gevaert P, et al. Calcineurin inhibitors dampen humoral immunity by acting directly on naive B cells. Clin Exp Immunol. 2015;180:542-50 pubmed publisher

Zhang H, Wang S, Huang Y, Wang H, Zhao J, Gaskin F, et al. Myeloid-derived suppressor cells are proinflammatory and regulate collagen-induced arthritis through manipulating Th17 cell differentiation. Clin Immunol. 2015;157:175-86 pubmed publisher

Pannu J, Belle J, Forster M, Duerr C, Shen S, Kane L, et al. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS ONE. 2015;10:e0117304 pubmed publisher

Nakanishi K, Kakiguchi K, Yonemura S, Nakano A, Morishima N. Transient Ca2+ depletion from the endoplasmic reticulum is critical for skeletal myoblast differentiation. FASEB J. 2015;29:2137-49 pubmed publisher

Macdonald K, Dawson N, Huang Q, Dunne J, Levings M, Broady R. Regulatory T cells produce profibrotic cytokines in the skin of patients with systemic sclerosis. J Allergy Clin Immunol. 2015;135:946-.e9 pubmed publisher

Vujicic M, Nikolic I, Kontogianni V, Saksida T, Charisiadis P, Orescanin Dusić Z, et al. Methanolic extract of Origanum vulgare ameliorates type 1 diabetes through antioxidant, anti-inflammatory and anti-apoptotic activity. Br J Nutr. 2015;113:770-82 pubmed publisher

Boland B, Widjaja C, Banno A, Zhang B, Kim S, Stoven S, et al. Immunodeficiency and autoimmune enterocolopathy linked to NFAT5 haploinsufficiency. J Immunol. 2015;194:2551-60 pubmed publisher

Lightfoot Y, Selle K, Yang T, Goh Y, Sahay B, Zadeh M, et al. SIGNR3-dependent immune regulation by Lactobacillus acidophilus surface layer protein A in colitis. EMBO J. 2015;34:881-95 pubmed publisher

Orio J, Carli C, Janelle V, Giroux M, Taillefer J, Goupil M, et al. Early exposure to interleukin-21 limits rapidly generated anti-Epstein-Barr virus T-cell line differentiation. Cytotherapy. 2015;17:496-508 pubmed publisher

Astry B, Venkatesha S, Laurence A, Christensen Quick A, Garzino Demo A, Frieman M, et al. Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ. Clin Immunol. 2015;157:228-38 pubmed publisher

Xu Y, Li Z, Yin Y, Lan H, Wang J, Zhao J, et al. Ghrelin inhibits the differentiation of T helper 17 cells through mTOR/STAT3 signaling pathway. PLoS ONE. 2015;10:e0117081 pubmed publisher

Nozaki Y, Kinoshita K, Hino S, Yano T, Niki K, Hirooka Y, et al. Signaling Rho-kinase mediates inflammation and apoptosis in T cells and renal tubules in cisplatin nephrotoxicity. Am J Physiol Renal Physiol. 2015;308:F899-909 pubmed publisher

Feng J, Hu Y, Song Z, Liu Y, Guo X, Jie Z. Interleukin-23 facilitates Th1 and Th2 cell differentiation in vitro following respiratory syncytial virus infection. J Med Virol. 2015;87:708-15 pubmed publisher

Peng Y, Gao X, Yang J, Shekhar S, Wang S, Fan Y, et al. Chlamydial lung infection induces transient IL-9 production which is redundant for host defense against primary infection. PLoS ONE. 2015;10:e0115195 pubmed publisher

Lu Y, Xue Q, Eisele M, Sulistijo E, Brower K, Han L, et al. Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands. Proc Natl Acad Sci U S A. 2015;112:E607-15 pubmed publisher

Boyle M, Jagannathan P, Bowen K, McIntyre T, Vance H, Farrington L, et al. Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations. J Infect Dis. 2015;212:416-25 pubmed publisher

Schubert R, Hu Y, Kumar G, Szeto S, Abraham P, Winderl J, et al. IFN-β treatment requires B cells for efficacy in neuroautoimmunity. J Immunol. 2015;194:2110-6 pubmed publisher

Lai L, Ong R, Li J, Albani S. A CD45-based barcoding approach to multiplex mass-cytometry (CyTOF). Cytometry A. 2015;87:369-74 pubmed publisher

Tang C, Isitman G, Bruneau J, Tremblay C, Bernard N, Kent S, et al. Phenotypical and functional profiles of natural killer cells exhibiting matrix metalloproteinase-mediated CD16 cleavage after anti-HIV antibody-dependent activation. Clin Exp Immunol. 2015;181:275-85 pubmed publisher

Peres A, Stegen C, Li J, Xu A, Levast B, Surette M, et al. Uncoupling of pro- and anti-inflammatory properties of Staphylococcus aureus. Infect Immun. 2015;83:1587-97 pubmed publisher

Ueno K, Kinjo Y, Okubo Y, Aki K, Urai M, Kaneko Y, et al. Dendritic cell-based immunization ameliorates pulmonary infection with highly virulent Cryptococcus gattii. Infect Immun. 2015;83:1577-86 pubmed publisher

Guo J, McQuillan J, Yau B, Tullo G, Long C, Bertolino P, et al. IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malaria. Infect Immun. 2015;83:1406-17 pubmed publisher

Sun T, Zhang D, Yang Y, Zhang X, Lv C, Fu R, et al. Interleukin 35 may contribute to the loss of immunological self-tolerance in patients with primary immune thrombocytopenia. Br J Haematol. 2015;169:278-85 pubmed publisher

Sercan Alp Ã, Durlanik S, Schulz D, McGrath M, Grün J, Bardua M, et al. Memory CD8(+) T cells colocalize with IL-7(+) stromal cells in bone marrow and rest in terms of proliferation and transcription. Eur J Immunol. 2015;45:975-87 pubmed publisher

Nogueira C, Zhang X, Giovannone N, Sennott E, Starnbach M. Protective immunity against Chlamydia trachomatis can engage both CD4+ and CD8+ T cells and bridge the respiratory and genital mucosae. J Immunol. 2015;194:2319-29 pubmed publisher

Benedicto I, Gondar V, Molina Jiménez F, García Buey L, López Cabrera M, Gastaminza P, et al. Clathrin mediates infectious hepatitis C virus particle egress. J Virol. 2015;89:4180-90 pubmed publisher

Vargas Inchaustegui D, Xiao P, Demberg T, Pal R, Robert Guroff M. Therapeutic envelope vaccination in combination with antiretroviral therapy temporarily rescues SIV-specific CD4⁺ T-cell-dependent natural killer cell effector responses in chronically infected rhesus macaques. Immunology. 2015;145:288-99 pubmed publisher

Huang K, Chen A, Zhang X, Song Z, Xu H, Cao J, et al. Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation. Immunology. 2015;145:279-87 pubmed publisher

Bontempi I, Vicco M, Cabrera G, Villar S, González F, Roggero E, et al. Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease. Vaccine. 2015;33:1274-83 pubmed publisher

Zhu F, Qiao J, Chen W, Pan B, Wu Q, Cao J, et al. Increased expression of T cell immune response cDNA 7 in patients with acute graft-versus-host disease. Ann Hematol. 2015;94:1025-32 pubmed publisher

Suehiro Y, Hasegawa A, Iino T, Sasada A, Watanabe N, Matsuoka M, et al. Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study. Br J Haematol. 2015;169:356-67 pubmed publisher

Gideon H, Phuah J, Myers A, Bryson B, Rodgers M, Coleman M, et al. Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization. PLoS Pathog. 2015;11:e1004603 pubmed publisher

Clayton K, Douglas Vail M, Nur Ur Rahman A, Medcalf K, Xie I, Chew G, et al. Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression. J Virol. 2015;89:3723-36 pubmed publisher

Li B, Gurung P, Malireddi R, Vogel P, Kanneganti T, Geiger T. IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T-cell-mediated colitis. Nat Commun. 2015;6:6131 pubmed publisher

Saadoun D, Garrido M, Comarmond C, Desbois A, Domont F, Savey L, et al. Th1 and Th17 cytokines drive inflammation in Takayasu arteritis. Arthritis Rheumatol. 2015;67:1353-60 pubmed publisher

Gaudreau M, Johnson B, Gudi R, Al Gadban M, Vasu C. Gender bias in lupus: does immune response initiated in the gut mucosa have a role?. Clin Exp Immunol. 2015;180:393-407 pubmed publisher

Wang F, Ni W, Liu G, Wang J, Xie F, Yuan H, et al. Escherichia coli maltose-binding protein (MBP) directly induces mouse Th1 activation through upregulating TLR2 and downregulating TLR4 expressions. Immunobiology. 2015;220:782-8 pubmed publisher

Carvalho A, Cristal J, Muniz A, Carvalho L, Gomes R, Miranda J, et al. Interleukin 10-Dominant Immune Response and Increased Risk of Cutaneous Leishmaniasis After Natural Exposure to Lutzomyia intermedia Sand Flies. J Infect Dis. 2015;212:157-65 pubmed publisher

Quinn M, Turula H, Tandon M, Deslouches B, Moghbeli T, Snyder C. Memory T cells specific for murine cytomegalovirus re-emerge after multiple challenges and recapitulate immunity in various adoptive transfer scenarios. J Immunol. 2015;194:1726-1736 pubmed publisher

Yang B, Floess S, Hagemann S, Deyneko I, Groebe L, Pezoldt J, et al. Development of a unique epigenetic signature during in vivo Th17 differentiation. Nucleic Acids Res. 2015;43:1537-48 pubmed publisher

Clouthier D, Zhou A, Wortzman M, Luft O, Levy G, Watts T. GITR intrinsically sustains early type 1 and late follicular helper CD4 T cell accumulation to control a chronic viral infection. PLoS Pathog. 2015;11:e1004517 pubmed publisher

Myster F, Palmeira L, Sorel O, Bouillenne F, Depauw E, Schwartz Cornil I, et al. Viral semaphorin inhibits dendritic cell phagocytosis and migration but is not essential for gammaherpesvirus-induced lymphoproliferation in malignant catarrhal fever. J Virol. 2015;89:3630-47 pubmed publisher

Fahel J, de Souza M, Gomes M, Corsetti P, Carvalho N, Marinho F, et al. 5-Lipoxygenase negatively regulates Th1 response during Brucella abortus infection in mice. Infect Immun. 2015;83:1210-6 pubmed publisher

Lee Y, Kim D, Lee E, Kim S, Choi C, Jun H. Sodium meta-arsenite prevents the development of autoimmune diabetes in NOD mice. Toxicol Appl Pharmacol. 2015;284:254-61 pubmed publisher

Hodge G, Jersmann H, Tran H, Holmes M, Reynolds P, Hodge S. Lymphocyte senescence in COPD is associated with loss of glucocorticoid receptor expression by pro-inflammatory/cytotoxic lymphocytes. Respir Res. 2015;16:2 pubmed publisher

Mateus J, Lasso P, Pavia P, Rosas F, Roa N, Valencia Hernández C, et al. Low frequency of circulating CD8+ T stem cell memory cells in chronic chagasic patients with severe forms of the disease. PLoS Negl Trop Dis. 2015;9:e3432 pubmed publisher

Saveljeva S, Mc Laughlin S, Vandenabeele P, Samali A, Bertrand M. Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells. Cell Death Dis. 2015;6:e1587 pubmed publisher

Norton T, Miller E, Bhardwaj N, Landau N. Vpx-containing dendritic cell vaccine induces CTLs and reactivates latent HIV-1 in vitro. Gene Ther. 2015;22:227-36 pubmed publisher

Huang F, Huang W, Briggs J, Chew T, Bai Y, Deol S, et al. The tyrosine kinase Itk suppresses CD8+ memory T cell development in response to bacterial infection. Sci Rep. 2015;5:7688 pubmed publisher

Zuo L, Yuan K, Yu L, Meng Q, Chung P, Yang D. Bifidobacterium infantis attenuates colitis by regulating T cell subset responses. World J Gastroenterol. 2014;20:18316-29 pubmed publisher

Li F, Ji L, Wang W, Hua F, Zhan Y, Zou S, et al. Insufficient secretion of IL-10 by Tregs compromised its control on over-activated CD4+ T effector cells in newly diagnosed adult immune thrombocytopenia patients. Immunol Res. 2015;61:269-80 pubmed publisher

McPherson R, Konkel J, Prendergast C, Thomson J, Ottaviano R, Leech M, et al. Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4(+) T cells tolerized by peptide immunotherapy. elife. 2014;3: pubmed publisher

Hermann F, Rodriguez Gomez M, Doser K, Edinger M, Hoffmann P, Schiechl G, et al. Basophils inhibit proliferation of CD4⁺ T cells in autologous and allogeneic mixed lymphocyte reactions and limit disease activity in a murine model of graft versus host disease. Immunology. 2015;145:202-12 pubmed publisher

Bodhankar S, Chen Y, Lapato A, Vandenbark A, Murphy S, Saugstad J, et al. Regulatory CD8(+)CD122 (+) T-cells predominate in CNS after treatment of experimental stroke in male mice with IL-10-secreting B-cells. Metab Brain Dis. 2015;30:911-924 pubmed publisher

Hesseling A, Tena Coki N, Scriba T, Chegou N, Kidd M, Wilkinson R, et al. The impact of HIV exposure and maternal Mycobacterium tuberculosis infection on infant immune responses to bacille Calmette-Guérin vaccination. AIDS. 2015;29:155-65 pubmed publisher

Cardoso T, Machado Ã, Costa D, Carvalho L, Queiroz A, Machado P, et al. Protective and pathological functions of CD8+ T cells in Leishmania braziliensis infection. Infect Immun. 2015;83:898-906 pubmed publisher

Maggio R, Viscomi C, Andreozzi P, D Ettorre G, Viscogliosi G, Barbaro B, et al. Normocaloric low cholesterol diet modulates Th17/Treg balance in patients with chronic hepatitis C virus infection. PLoS ONE. 2014;9:e112346 pubmed publisher

Shekhar S, Joyee A, Gao X, Peng Y, Wang S, Yang J, et al. Invariant Natural Killer T Cells Promote T Cell Immunity by Modulating the Function of Lung Dendritic Cells during Chlamydia pneumoniae Infection. J Innate Immun. 2015;7:260-74 pubmed publisher

Shen R, Deng W, Li C, Zeng G. A natural flavonoid glucoside icariin inhibits Th1 and Th17 cell differentiation and ameliorates experimental autoimmune encephalomyelitis. Int Immunopharmacol. 2015;24:224-231 pubmed publisher

Yuan X, Dee M, Altman N, Malek T. IL-2Rβ-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa. J Immunol. 2015;194:1334-46 pubmed publisher

Takeuchi A, Eto M, Tatsugami K, Yamada H, Yokomizo A, Shiota M, et al. Renal cancer treatment with recipient lymphocyte infusion enhanced the antitumor effect of nonmyeloablative allogeneic stem cell transplantation. Transpl Immunol. 2015;32:131-9 pubmed publisher

Mueller N, Avota E, Collenburg L, Grassme H, Schneider Schaulies S. Neutral sphingomyelinase in physiological and measles virus induced T cell suppression. PLoS Pathog. 2014;10:e1004574 pubmed publisher

Thiele F, Tao S, Zhang Y, Muschaweckh A, Zollmann T, Protzer U, et al. Modified vaccinia virus Ankara-infected dendritic cells present CD4+ T-cell epitopes by endogenous major histocompatibility complex class II presentation pathways. J Virol. 2015;89:2698-709 pubmed publisher

Hartung E, Becker M, Bachem A, Reeg N, Jäkel A, Hutloff A, et al. Induction of potent CD8 T cell cytotoxicity by specific targeting of antigen to cross-presenting dendritic cells in vivo via murine or human XCR1. J Immunol. 2015;194:1069-79 pubmed publisher

Watanabe K, Terakura S, Martens A, van Meerten T, Uchiyama S, Imai M, et al. Target antigen density governs the efficacy of anti-CD20-CD28-CD3 ζ chimeric antigen receptor-modified effector CD8+ T cells. J Immunol. 2015;194:911-20 pubmed publisher

Bernard N, Finlay C, Tannahill G, Cassidy J, O Neill L, Mills K. A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis. Mucosal Immunol. 2015;8:982-92 pubmed publisher

Van Epps P, Banks R, Aung H, Betts M, Canaday D. Age-related differences in polyfunctional T cell responses. Immun Ageing. 2014;11:14 pubmed publisher

White C, Villarino N, Sloan S, Ganusov V, Schmidt N. Plasmodium suppresses expansion of T cell responses to heterologous infections. J Immunol. 2015;194:697-708 pubmed publisher

Schuetz A, Deléage C, Sereti I, Rerknimitr R, Phanuphak N, Phuang Ngern Y, et al. Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation. PLoS Pathog. 2014;10:e1004543 pubmed publisher

Støy S, Dige A, Sandahl T, Laursen T, Buus C, Hokland M, et al. Cytotoxic T lymphocytes and natural killer cells display impaired cytotoxic functions and reduced activation in patients with alcoholic hepatitis. Am J Physiol Gastrointest Liver Physiol. 2015;308:G269-76 pubmed publisher

Dimitrov S, Besedovsky L, Born J, Lange T. Differential acute effects of sleep on spontaneous and stimulated production of tumor necrosis factor in men. Brain Behav Immun. 2015;47:201-10 pubmed publisher

Zhang W, Zhang J, Zhao L, Shao J, Cui J, Guo C, et al. TIPE2 protein negatively regulates HBV-specific CD8⁺ T lymphocyte functions in humans. Mol Immunol. 2015;64:204-9 pubmed publisher

Pierdominici M, Maselli A, Cecchetti S, Tinari A, Mastrofrancesco A, Alfè M, et al. Diesel exhaust particle exposure in vitro impacts T lymphocyte phenotype and function. Part Fibre Toxicol. 2014;11:74 pubmed publisher

Tan M, Gerry A, Brewer J, Melchiori L, Bridgeman J, Bennett A, et al. T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cells. Clin Exp Immunol. 2015;180:255-70 pubmed publisher

Obata Y, Toyoshima S, Wakamatsu E, Suzuki S, Ogawa S, Esumi H, et al. Oncogenic Kit signals on endolysosomes and endoplasmic reticulum are essential for neoplastic mast cell proliferation. Nat Commun. 2014;5:5715 pubmed publisher

Falcón C, Masih D, Gatti G, Sanchez M, Motran C, Cervi L. Fasciola hepatica Kunitz type molecule decreases dendritic cell activation and their ability to induce inflammatory responses. PLoS ONE. 2014;9:e114505 pubmed publisher

Kenefeck R, Wang C, Kapadi T, Wardzinski L, Attridge K, Clough L, et al. Follicular helper T cell signature in type 1 diabetes. J Clin Invest. 2015;125:292-303 pubmed publisher

Zhang H, Tang K, Zhang Y, Ma R, Ma J, Li Y, et al. Cell-free tumor microparticle vaccines stimulate dendritic cells via cGAS/STING signaling. Cancer Immunol Res. 2015;3:196-205 pubmed publisher

Peters N, Pagán A, Lawyer P, Hand T, Henrique Roma E, Stamper L, et al. Chronic parasitic infection maintains high frequencies of short-lived Ly6C+CD4+ effector T cells that are required for protection against re-infection. PLoS Pathog. 2014;10:e1004538 pubmed publisher

Zimmermann K, Liechti T, Haas A, Rehr M, Trkola A, Günthard H, et al. The orientation of HIV-1 gp120 binding to the CD4 receptor differentially modulates CD4+ T cell activation. J Immunol. 2015;194:637-49 pubmed publisher

Xuan N, Wang X, Nishanth G, Waisman A, Borucki K, Isermann B, et al. A20 expression in dendritic cells protects mice from LPS-induced mortality. Eur J Immunol. 2015;45:818-28 pubmed publisher

Pickford W, Gudi V, Haggart A, Lewis B, Herriot R, Barker R, et al. T cell participation in autoreactivity to NC16a epitopes in bullous pemphigoid. Clin Exp Immunol. 2015;180:189-200 pubmed publisher

Blanco R, Borroto A, Schamel W, Pereira P, Alarcon B. Conformational changes in the T cell receptor differentially determine T cell subset development in mice. Sci Signal. 2014;7:ra115 pubmed publisher

Dong Z, Gong K, Huang D, Zhu W, Sun W, Zhang Y, et al. Myocardial infarction accelerates glomerular injury and microalbuminuria in diabetic rats via local hemodynamics and immunity. Int J Cardiol. 2015;179:397-408 pubmed publisher

Maine C, Marquardt K, Scatizzi J, Pollard K, Kono D, Sherman L. The effect of the autoimmunity-associated gene, PTPN22, on a BXSB-derived model of lupus. Clin Immunol. 2015;156:65-73 pubmed publisher

Aihara N, Kamiie J, Yamada M, Shirota K. The development of mixed cryoglobulinemia in Capillaria hepatica-infected mice is associated with the capillaria antigen-induced selective proliferation of splenic B-1a cells in response to interleukin-5 stimulation. Am J Pathol. 2015;185:172-84 pubmed publisher

Irwin M, Witarama T, Caudill M, Olmstead R, Breen E. Sleep loss activates cellular inflammation and signal transducer and activator of transcription (STAT) family proteins in humans. Brain Behav Immun. 2015;47:86-92 pubmed publisher

van der Geest K, Abdulahad W, Tete S, Lorencetti P, Horst G, Bos N, et al. Aging disturbs the balance between effector and regulatory CD4+ T cells. Exp Gerontol. 2014;60:190-6 pubmed publisher

Cruz A, Torrado E, Carmona J, Fraga A, Costa P, Rodrigues F, et al. BCG vaccination-induced long-lasting control of Mycobacterium tuberculosis correlates with the accumulation of a novel population of CD4⁺IL-17⁺TNF⁺IL-2⁺ T cells. Vaccine. 2015;33:85-91 pubmed publisher

Pérol L, Martin G, Maury S, Cohen J, Piaggio E. Potential limitations of IL-2 administration for the treatment of experimental acute graft-versus-host disease. Immunol Lett. 2014;162:173-84 pubmed publisher

Gaiser M, Textor S, Senger T, Schädlich L, Waterboer T, Kaufmann A, et al. Evaluation of specific humoral and cellular immune responses against the major capsid L1 protein of cutaneous wart-associated alpha-Papillomaviruses in solid organ transplant recipients. J Dermatol Sci. 2015;77:37-45 pubmed publisher

Heylen M, Ruyssers N, Nullens S, Schramm G, Pelckmans P, Moreels T, et al. Treatment with egg antigens of Schistosoma mansoni ameliorates experimental colitis in mice through a colonic T-cell-dependent mechanism. Inflamm Bowel Dis. 2015;21:48-59 pubmed publisher

Dotson A, Wang J, Saugstad J, Murphy S, Offner H. Splenectomy reduces infarct volume and neuroinflammation in male but not female mice in experimental stroke. J Neuroimmunol. 2015;278:289-98 pubmed publisher

Mohn K, Bredholt G, Brokstad K, Pathirana R, Aarstad H, Tøndel C, et al. Longevity of B-cell and T-cell responses after live attenuated influenza vaccination in children. J Infect Dis. 2015;211:1541-9 pubmed publisher

Hokey D, Wachholder R, Darrah P, Bolton D, Barouch D, Hill K, et al. A nonhuman primate toxicology and immunogenicity study evaluating aerosol delivery of AERAS-402/Ad35 vaccine: Evidence for transient t cell responses in peripheral blood and robust sustained responses in the lungs. Hum Vaccin Immunother. 2014;10:2199-210 pubmed publisher

Botta Gordon Smith S, Ursu S, Eaton S, Moncrieffe H, Wedderburn L. Correlation of low CD73 expression on synovial lymphocytes with reduced adenosine generation and higher disease severity in juvenile idiopathic arthritis. Arthritis Rheumatol. 2015;67:545-54 pubmed publisher

Cohen S, Smith N, McDougal C, Pepper M, Shah S, Yap G, et al. Beta-catenin signaling drives differentiation and proinflammatory function of IRF8-dependent dendritic cells. J Immunol. 2015;194:210-22 pubmed

Kristensen B, Hegedüs L, Madsen H, Smith T, Nielsen C. Altered balance between self-reactive T helper (Th)17 cells and Th10 cells and between full-length forkhead box protein 3 (FoxP3) and FoxP3 splice variants in Hashimoto's thyroiditis. Clin Exp Immunol. 2015;180:58-69 pubmed publisher

Gaddipati S, Estrada K, Rao P, Jerome A, Suvas S. IL-2/anti-IL-2 antibody complex treatment inhibits the development but not the progression of herpetic stromal keratitis. J Immunol. 2015;194:273-82 pubmed publisher

Meyer C, Engelmann F, Arnold N, Krah D, Ter Meulen J, Haberthur K, et al. Abortive intrabronchial infection of rhesus macaques with varicella-zoster virus provides partial protection against simian varicella virus challenge. J Virol. 2015;89:1781-93 pubmed publisher

Cozza E, Cooper T, Budgeon L, Christensen N, Schell T. Protection from tumor recurrence following adoptive immunotherapy varies with host conditioning regimen despite initial regression of autochthonous murine brain tumors. Cancer Immunol Immunother. 2015;64:325-36 pubmed publisher

Buchan S, Manzo T, Flutter B, Rogel A, Edwards N, Zhang L, et al. OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence. J Immunol. 2015;194:125-133 pubmed publisher

Ordonez A, Pokkali S, DeMarco V, Klunk M, Mease R, Foss C, et al. Radioiodinated DPA-713 imaging correlates with bactericidal activity of tuberculosis treatments in mice. Antimicrob Agents Chemother. 2015;59:642-9 pubmed publisher

Yan J, Tingey C, Lyde R, Gorham T, Choo D, Muthumani A, et al. Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model. Cancer Gene Ther. 2014;21:507-17 pubmed publisher

Elliott J, Wightman F, Solomon A, Ghneim K, Ahlers J, Cameron M, et al. Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy. PLoS Pathog. 2014;10:e1004473 pubmed publisher

Kamburova E, Koenen H, van den Hoogen M, Baas M, Joosten I, Hilbrands L. Longitudinal analysis of T and B cell phenotype and function in renal transplant recipients with or without rituximab induction therapy. PLoS ONE. 2014;9:e112658 pubmed publisher

McIlwain D, Grusdat M, Pozdeev V, Xu H, Shinde P, Reardon C, et al. T-cell STAT3 is required for the maintenance of humoral immunity to LCMV. Eur J Immunol. 2015;45:418-27 pubmed publisher

Prajeeth C, Beineke A, Iskandar C, Gudi V, Herder V, Gerhauser I, et al. Limited role of regulatory T cells during acute Theiler virus-induced encephalitis in resistant C57BL/6 mice. J Neuroinflammation. 2014;11:180 pubmed publisher

Chen S, Su Y, Lu Y, Ko P, Chang P, Lin H, et al. Defects in the acquisition of tumor-killing capability of CD8+ cytotoxic T cells in streptozotocin-induced diabetic mice. PLoS ONE. 2014;9:e109961 pubmed publisher

Francois V, Shehade H, Acolty V, Preyat N, Delrée P, Moser M, et al. Intestinal immunopathology is associated with decreased CD73-generated adenosine during lethal infection. Mucosal Immunol. 2015;8:773-84 pubmed publisher

Varypataki E, van der Maaden K, Bouwstra J, Ossendorp F, Jiskoot W. Cationic liposomes loaded with a synthetic long peptide and poly(I:C): a defined adjuvanted vaccine for induction of antigen-specific T cell cytotoxicity. AAPS J. 2015;17:216-26 pubmed publisher

Arndt B, Witkowski L, Ellwart J, Seissler J. CD8+ CD122+ PD-1- effector cells promote the development of diabetes in NOD mice. J Leukoc Biol. 2015;97:111-20 pubmed publisher

Said A, Bock S, Lajqi T, Müller G, Weindl G. Chloroquine promotes IL-17 production by CD4+ T cells via p38-dependent IL-23 release by monocyte-derived Langerhans-like cells. J Immunol. 2014;193:6135-43 pubmed publisher

Schinnerling K, Geelhaar Karsch A, Allers K, Friebel J, Conrad K, Loddenkemper C, et al. Role of dendritic cells in the pathogenesis of Whipple's disease. Infect Immun. 2015;83:482-91 pubmed publisher

Sieber J, Daridon C, Fleischer S, Fleischer V, Hiepe F, Alexander T, et al. Active systemic lupus erythematosus is associated with a reduced cytokine production by B cells in response to TLR9 stimulation. Arthritis Res Ther. 2014;16:477 pubmed publisher

Wei L, Jin Q, Chu Y, Wu S, Huang R. Suppression of dendritic cell and T-cell activation by the pRST⁹⁸ Salmonella plasmid. Mol Med Rep. 2015;11:2306-14 pubmed publisher

Ma Z, LeBard D, Loverde S, Sharp K, Klein M, Discher D, et al. TCR triggering by pMHC ligands tethered on surfaces via poly(ethylene glycol) depends on polymer length. PLoS ONE. 2014;9:e112292 pubmed publisher

Shi D, Li D, Yin Q, Qiu Y, Yan H, Shen Y, et al. Silenced suppressor of cytokine signaling 1 (SOCS1) enhances the maturation and antifungal immunity of dendritic cells in response to Candida albicans in vitro. Immunol Res. 2015;61:206-18 pubmed publisher

Delpoux A, Yakonowsky P, Durand A, Charvet C, Valente M, Pommier A, et al. TCR signaling events are required for maintaining CD4 regulatory T cell numbers and suppressive capacities in the periphery. J Immunol. 2014;193:5914-23 pubmed publisher

Yang O, Ali A, Kasahara N, Faure Kumar E, Bae J, Picker L, et al. Short conserved sequences of HIV-1 are highly immunogenic and shift immunodominance. J Virol. 2015;89:1195-204 pubmed publisher

Li Y, Zhou W, Du J, Jiang C, Xie X, Xue T, et al. Generation of cytotoxic T lymphocytes specific for native or modified peptides derived from the epidermal growth factor receptor pathway substrate 8 antigen. Cancer Immunol Immunother. 2015;64:259-69 pubmed publisher

Machino Ohtsuka T, Tajiri K, Kimura T, Sakai S, Sato A, Yoshida T, et al. Tenascin-C aggravates autoimmune myocarditis via dendritic cell activation and Th17 cell differentiation. J Am Heart Assoc. 2014;3:e001052 pubmed publisher

Burkard C, Verheije M, Wicht O, van Kasteren S, van Kuppeveld F, Haagmans B, et al. Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner. PLoS Pathog. 2014;10:e1004502 pubmed publisher

Chi L, Gao W, Shu X, Lu X. A natural flavonoid glucoside, icariin, regulates Th17 and alleviates rheumatoid arthritis in a murine model. Mediators Inflamm. 2014;2014:392062 pubmed publisher

Liang D, Zuo A, Shao H, Chen M, Kaplan H, Sun D. Anti-inflammatory or proinflammatory effect of an adenosine receptor agonist on the Th17 autoimmune response is inflammatory environment-dependent. J Immunol. 2014;193:5498-505 pubmed publisher

Boltjes A, van Montfoort N, Biesta P, Op den Brouw M, Kwekkeboom J, van der Laan L, et al. Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function. J Infect Dis. 2015;211:1268-78 pubmed publisher

Huang Y, Tsai K, Ma C, Vallance B, Priatel J, Tan R. SLAM-SAP signaling promotes differentiation of IL-17-producing T cells and progression of experimental autoimmune encephalomyelitis. J Immunol. 2014;193:5841-53 pubmed publisher

Oren R, Hod Marco M, Haus Cohen M, Thomas S, Blat D, Duvshani N, et al. Functional comparison of engineered T cells carrying a native TCR versus TCR-like antibody-based chimeric antigen receptors indicates affinity/avidity thresholds. J Immunol. 2014;193:5733-43 pubmed publisher

Nivarthi U, Gras S, Kjer Nielsen L, Berry R, Lucet I, Miles J, et al. An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant. J Immunol. 2014;193:5402-13 pubmed publisher

Fang M, Remakus S, Roscoe F, Ma X, Sigal L. CD4+ T cell help is dispensable for protective CD8+ T cell memory against mousepox virus following vaccinia virus immunization. J Virol. 2015;89:776-83 pubmed publisher

Rist M, Neller M, Burrows J, Burrows S. T cell epitope clustering in the highly immunogenic BZLF1 antigen of Epstein-Barr virus. J Virol. 2015;89:703-12 pubmed publisher

Qian F, Goel G, Meng H, Wang X, You F, Devine L, et al. Systems immunology reveals markers of susceptibility to West Nile virus infection. Clin Vaccine Immunol. 2015;22:6-16 pubmed publisher

Viant C, Fenis A, Chicanne G, Payrastre B, Ugolini S, Vivier E. SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells. Nat Commun. 2014;5:5108 pubmed publisher

Kim T, Jin H, Hur S, Yang H, Seo Y, Hong S, et al. Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients. Nat Commun. 2014;5:5317 pubmed publisher

Wang W, Jiao Z, Duan T, Liu M, Zhu B, Zhang Y, et al. Functional characterization of myeloid-derived suppressor cell subpopulations during the development of experimental arthritis. Eur J Immunol. 2015;45:464-73 pubmed publisher

Haapaniemi E, Kaustio M, Rajala H, van Adrichem A, Kainulainen L, Glumoff V, et al. Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3. Blood. 2015;125:639-48 pubmed publisher

Hill B, Darrah P, Ende Z, Ambrozak D, Quinn K, Darko S, et al. Epitope specificity delimits the functional capabilities of vaccine-induced CD8 T cell populations. J Immunol. 2014;193:5626-36 pubmed publisher

Pishraft Sabet L, Kosinska A, Rafati S, Bolhassani A, Taheri T, Memarnejadian A, et al. Enhancement of HCV polytope DNA vaccine efficacy by fusion to an N-terminal fragment of heat shock protein gp96. Arch Virol. 2015;160:141-52 pubmed publisher

Kim S, Park K, Choi J, Jang E, Paik D, Seong R, et al. Foxp3+ regulatory T cells ensure B lymphopoiesis by inhibiting the granulopoietic activity of effector T cells in mouse bone marrow. Eur J Immunol. 2015;45:167-79 pubmed publisher

Lin R, Chen L, Chen G, Hu C, Jiang S, Sevilla J, et al. Targeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression. J Clin Invest. 2014;124:5352-67 pubmed publisher

He L, Weidlick J, Sisson C, Marsh H, Keler T. Toll-like receptor agonists shape the immune responses to a mannose receptor-targeted cancer vaccine. Cell Mol Immunol. 2015;12:719-28 pubmed publisher

Chiurchiù V, Lanuti M, De Bardi M, Battistini L, Maccarrone M. The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells. Int Immunol. 2015;27:153-60 pubmed publisher

Tomita Y, Yuno A, Tsukamoto H, Senju S, Kuroda Y, Hirayama M, et al. Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant disease. Oncoimmunology. 2014;3:e28100 pubmed

Remmerswaal E, Klarenbeek P, Alves N, Doorenspleet M, van Schaik B, Esveldt R, et al. Clonal evolution of CD8+ T cell responses against latent viruses: relationship among phenotype, localization, and function. J Virol. 2015;89:568-80 pubmed publisher

Murphy L, Varela M, Desloire S, Ftaich N, Murgia C, Golder M, et al. The sheep tetherin paralog oBST2B blocks envelope glycoprotein incorporation into nascent retroviral virions. J Virol. 2015;89:535-44 pubmed publisher

Duffy M, McNicholas B, Monaghan D, Hanley S, McMahon J, Pindjáková J, et al. Mesenchymal stem cells and a vitamin D receptor agonist additively suppress T helper 17 cells and the related inflammatory response in the kidney. Am J Physiol Renal Physiol. 2014;307:F1412-26 pubmed publisher

Popescu I, Pipeling M, Shah P, Orens J, McDyer J. T-bet:Eomes balance, effector function, and proliferation of cytomegalovirus-specific CD8+ T cells during primary infection differentiates the capacity for durable immune control. J Immunol. 2014;193:5709-5722 pubmed publisher

Chevalier N, Thorburn A, Macia L, Tan J, Juglair L, Yagita H, et al. Inflammation and lymphopenia trigger autoimmunity by suppression of IL-2-controlled regulatory T cell and increase of IL-21-mediated effector T cell expansion. J Immunol. 2014;193:4845-58 pubmed publisher

Pericolini E, Gabrielli E, Alunno A, Bartoloni Bocci E, Perito S, Chow S, et al. Functional improvement of regulatory T cells from rheumatoid arthritis subjects induced by capsular polysaccharide glucuronoxylomannogalactan. PLoS ONE. 2014;9:e111163 pubmed publisher

Arrode Brusés G, Moussa M, Baccard Longère M, Villinger F, Chebloune Y. Long-term central and effector SHIV-specific memory T cell responses elicited after a single immunization with a novel lentivector DNA vaccine. PLoS ONE. 2014;9:e110883 pubmed publisher

van der Waart A, van de Weem N, Maas F, Kramer C, Kester M, Falkenburg J, et al. Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy. Blood. 2014;124:3490-500 pubmed publisher

Suarez Ramirez J, Tarrio M, Kim K, Demers D, Biron C. CD8 T cells in innate immune responses: using STAT4-dependent but antigen-independent pathways to gamma interferon during viral infection. MBio. 2014;5:e01978-14 pubmed publisher

Sun W, Li W, Fu Q, Wu C, Lin J, Zhu X, et al. Functionally distinct subsets of CD4⁺ regulatory T cells in patients with laryngeal squamous cell carcinoma are indicative of immune deregulation and disease progression. Oncol Rep. 2015;33:354-62 pubmed publisher

Lepletier A, de Almeida L, Santos L, da Silva Sampaio L, Paredes B, González F, et al. Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease. PLoS Negl Trop Dis. 2014;8:e3203 pubmed publisher

Luetke Eversloh M, Hammer Q, Durek P, Nordström K, Gasparoni G, Pink M, et al. Human cytomegalovirus drives epigenetic imprinting of the IFNG locus in NKG2Chi natural killer cells. PLoS Pathog. 2014;10:e1004441 pubmed publisher

Weiskopf D, Angelo M, Bangs D, Sidney J, Paul S, Peters B, et al. The human CD8+ T cell responses induced by a live attenuated tetravalent dengue vaccine are directed against highly conserved epitopes. J Virol. 2015;89:120-8 pubmed publisher

Çuburu N, Wang K, Goodman K, Pang Y, Thompson C, Lowy D, et al. Topical herpes simplex virus 2 (HSV-2) vaccination with human papillomavirus vectors expressing gB/gD ectodomains induces genital-tissue-resident memory CD8+ T cells and reduces genital disease and viral shedding after HSV-2 challenge. J Virol. 2015;89:83-96 pubmed publisher

Nitschke K, Flecken T, Schmidt J, Gostick E, Marget M, Neumann Haefelin C, et al. Tetramer enrichment reveals the presence of phenotypically diverse hepatitis C virus-specific CD8+ T cells in chronic infection. J Virol. 2015;89:25-34 pubmed publisher

Janczy J, Ciraci C, Haasken S, Iwakura Y, Olivier A, CASSEL S, et al. Immune complexes inhibit IL-1 secretion and inflammasome activation. J Immunol. 2014;193:5190-8 pubmed publisher

Chang F, Kawashima S, Brady S. Mutations in the proteolipid subunits of the vacuolar H+-ATPase provide resistance to indolotryptoline natural products. Biochemistry. 2014;53:7123-31 pubmed publisher

Jaworski M, Marsland B, Gehrig J, Held W, Favre S, Luther S, et al. Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity. EMBO J. 2014;33:2765-81 pubmed publisher

McDonnell A, Lesterhuis W, Khong A, Nowak A, Lake R, Currie A, et al. Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy. Eur J Immunol. 2015;45:49-59 pubmed publisher

Dunne A, Mielke L, Allen A, Sutton C, Higgs R, Cunningham C, et al. A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine. Mucosal Immunol. 2015;8:607-17 pubmed publisher

Hart Matyas M, Gareau A, Hirsch G, Lee T. De novo alloreactive memory CD8+ T cells develop following allogeneic challenge when CNI immunosuppression is delayed. Transpl Immunol. 2015;32:23-8 pubmed publisher

Heylen M, Ruyssers N, De Man J, Timmermans J, Pelckmans P, Moreels T, et al. Worm proteins of Schistosoma mansoni reduce the severity of experimental chronic colitis in mice by suppressing colonic proinflammatory immune responses. PLoS ONE. 2014;9:e110002 pubmed publisher

Bitsaktsis C, Babadjanova Z, Gosselin E. In vivo mechanisms involved in enhanced protection utilizing an Fc receptor-targeted mucosal vaccine platform in a bacterial vaccine and challenge model. Infect Immun. 2015;83:77-89 pubmed publisher

Blevins L, Wren J, Holbrook B, Hayward S, Swords W, Parks G, et al. Coinfection with Streptococcus pneumoniae negatively modulates the size and composition of the ongoing influenza-specific CD8⁺ T cell response. J Immunol. 2014;193:5076-87 pubmed publisher

Tong L, Nanjundaiah S, Venkatesha S, Astry B, Yu H, Moudgil K. Pristimerin, a naturally occurring triterpenoid, protects against autoimmune arthritis by modulating the cellular and soluble immune mediators of inflammation and tissue damage. Clin Immunol. 2014;155:220-30 pubmed publisher

Shi P, Grobe J, Desland F, Zhou G, Shen X, Shan Z, et al. Direct pro-inflammatory effects of prorenin on microglia. PLoS ONE. 2014;9:e92937 pubmed publisher

Tellam J, Zhong J, Lekieffre L, Bhat P, Martinez M, Croft N, et al. mRNA Structural constraints on EBNA1 synthesis impact on in vivo antigen presentation and early priming of CD8+ T cells. PLoS Pathog. 2014;10:e1004423 pubmed publisher

Ishii N, Funami K, Tatematsu M, Seya T, Matsumoto M. Endosomal localization of TLR8 confers distinctive proteolytic processing on human myeloid cells. J Immunol. 2014;193:5118-28 pubmed publisher

McKinnon L, Nyanga B, Kim C, Izulla P, Kwatampora J, Kimani M, et al. Early HIV-1 infection is associated with reduced frequencies of cervical Th17 cells. J Acquir Immune Defic Syndr. 2015;68:6-12 pubmed publisher

Lebouché B, Jenabian M, Singer J, Graziani G, Engler K, Trottier B, et al. The role of extended-release niacin on immune activation and neurocognition in HIV-infected patients treated with antiretroviral therapy - CTN PT006: study protocol for a randomized controlled trial. Trials. 2014;15:390 pubmed publisher

Tullius S, Biefer H, Li S, Trachtenberg A, Edtinger K, Quante M, et al. NAD+ protects against EAE by regulating CD4+ T-cell differentiation. Nat Commun. 2014;5:5101 pubmed publisher

Jansen D, Hameetman M, van Bergen J, Huizinga T, van der Heijde D, Toes R, et al. IL-17-producing CD4+ T cells are increased in early, active axial spondyloarthritis including patients without imaging abnormalities. Rheumatology (Oxford). 2015;54:728-35 pubmed publisher

Yamazaki Y, Yamada M, Kawai T, Morio T, Onodera M, Ueki M, et al. Two novel gain-of-function mutations of STAT1 responsible for chronic mucocutaneous candidiasis disease: impaired production of IL-17A and IL-22, and the presence of anti-IL-17F autoantibody. J Immunol. 2014;193:4880-7 pubmed publisher

Lendermon E, Dodd O J, Coon T, Miller H, Ganguly S, Popescu I, et al. CD8(+)IL-17(+) T Cells Mediate Neutrophilic Airway Obliteration in T-bet-Deficient Mouse Lung Allograft Recipients. Am J Respir Cell Mol Biol. 2015;52:622-33 pubmed publisher

Kim I, WU G, Chai N, Klein A, Jordan S. Anti-interleukin 6 receptor antibodies attenuate antibody recall responses in a mouse model of allosensitization. Transplantation. 2014;98:1262-70 pubmed publisher

Hossain D, Panda A, Chakrabarty S, Bhattacharjee P, Kajal K, Mohanty S, et al. MEK inhibition prevents tumour-shed transforming growth factor-β-induced T-regulatory cell augmentation in tumour milieu. Immunology. 2015;144:561-73 pubmed publisher

Clouthier D, Zhou A, Watts T. Anti-GITR agonist therapy intrinsically enhances CD8 T cell responses to chronic lymphocytic choriomeningitis virus (LCMV), thereby circumventing LCMV-induced downregulation of costimulatory GITR ligand on APC. J Immunol. 2014;193:5033-43 pubmed publisher

Zhang Y, Lv G, Lou X, Peng D, Qu X, Yang X, et al. NKG2A expression and impaired function of NK cells in patients with new onset of Graves' disease. Int Immunopharmacol. 2015;24:133-9 pubmed publisher

Anitei M, Chenna R, Czupalla C, Esner M, Christ S, Lenhard S, et al. A high-throughput siRNA screen identifies genes that regulate mannose 6-phosphate receptor trafficking. J Cell Sci. 2014;127:5079-92 pubmed publisher

Schindler M, Drozdenko G, Kühl A, Worm M. Immunomodulation in patients with chronic hand eczema treated with oral alitretinoin. Int Arch Allergy Immunol. 2014;165:18-26 pubmed publisher

Andrade B, Singh A, Narendran G, Schechter M, Nayak K, Subramanian S, et al. Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor of tuberculosis-associated immune reconstitution inflammatory syndrome. PLoS Pathog. 2014;10:e1004433 pubmed publisher

Terahara K, Ishii H, Nomura T, Takahashi N, Takeda A, Shiino T, et al. Vaccine-induced CD107a+ CD4+ T cells are resistant to depletion following AIDS virus infection. J Virol. 2014;88:14232-40 pubmed publisher

Bart P, Huang Y, Karuna S, Chappuis S, Gaillard J, Kochar N, et al. HIV-specific humoral responses benefit from stronger prime in phase Ib clinical trial. J Clin Invest. 2014;124:4843-56 pubmed publisher

Prados Rosales R, Carreño L, Batista Gonzalez A, Baena A, Venkataswamy M, Xu J, et al. Mycobacterial membrane vesicles administered systemically in mice induce a protective immune response to surface compartments of Mycobacterium tuberculosis. MBio. 2014;5:e01921-14 pubmed publisher

Kyrova K, Stepanova H, Rychlik I, Polansky O, Leva L, Sekelova Z, et al. The response of porcine monocyte derived macrophages and dendritic cells to Salmonella Typhimurium and lipopolysaccharide. BMC Vet Res. 2014;10:244 pubmed publisher

Meng Y, Xiong X, Qi Y, Duan C, Gong W, Jiao J, et al. Protective immunity against Rickettsia heilongjiangensis in a C3H/HeN mouse model mediated by outer membrane protein B-pulsed dendritic cells. Sci China Life Sci. 2015;58:287-96 pubmed publisher

Wang X, Wang G, Gong Y, Liu Y, Gu J, Chen W, et al. Disruption of circulating CD4+ T-lymphocyte subpopulations in psoriasis patients is ameliorated by narrow-band UVB therapy. Cell Biochem Biophys. 2015;71:499-507 pubmed publisher

Maciel B, Lima Maciel B, Valverde J, Rodrigues Neto J, Freire Neto F, Keesen T, et al. Dual immune modulatory effect of vitamin A in human visceral leishmaniasis. PLoS ONE. 2014;9:e107564 pubmed publisher

Kersh A, Edwards L, Evavold B. Progression of relapsing-remitting demyelinating disease does not require increased TCR affinity or epitope spread. J Immunol. 2014;193:4429-38 pubmed publisher

Pan Q, Pan K, Wang Q, Weng D, Zhao J, Zheng H, et al. Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells. Stem Cells. 2015;33:354-66 pubmed publisher

Gong Y, Zhao C, Zhao P, Wang M, Zhou G, Han F, et al. Role of IL-10-Producing Regulatory B Cells in Chronic Hepatitis B Virus Infection. Dig Dis Sci. 2015;60:1308-14 pubmed publisher

de Wit J, Jorritsma T, Makuch M, Remmerswaal E, Klaasse Bos H, Souwer Y, et al. Human B cells promote T-cell plasticity to optimize antibody response by inducing coexpression of T(H)1/T(FH) signatures. J Allergy Clin Immunol. 2015;135:1053-60 pubmed publisher

Kasamatsu J, Takahashi S, Azuma M, Matsumoto M, Morii Sakai A, Imamura M, et al. PolyI:C and mouse survivin artificially embedding human 2B peptide induce a CD4+ T cell response to autologous survivin in HLA-A*2402 transgenic mice. Immunobiology. 2015;220:74-82 pubmed publisher

Kay A, Fukuyama J, Aziz N, Dekker C, Mackey S, Swan G, et al. Enhanced natural killer-cell and T-cell responses to influenza A virus during pregnancy. Proc Natl Acad Sci U S A. 2014;111:14506-11 pubmed publisher

Yu C, Becker C, Metang P, Marches F, Wang Y, Toshiyuki H, et al. Human CD141+ dendritic cells induce CD4+ T cells to produce type 2 cytokines. J Immunol. 2014;193:4335-43 pubmed publisher

Mylvaganam G, Velu V, Hong J, Sadagopal S, Kwa S, Basu R, et al. Diminished viral control during simian immunodeficiency virus infection is associated with aberrant PD-1hi CD4 T cell enrichment in the lymphoid follicles of the rectal mucosa. J Immunol. 2014;193:4527-36 pubmed publisher

Miller G, Murphy M, Cashman R, Ma R, Ma J, Arevalo J, et al. Greater inflammatory activity and blunted glucocorticoid signaling in monocytes of chronically stressed caregivers. Brain Behav Immun. 2014;41:191-9 pubmed publisher

Gao Z, Zhao X, Yang T, Shang J, Shang L, Mai H, et al. Immunomodulation therapy of diabetes by oral administration of a surfactin lipopeptide in NOD mice. Vaccine. 2014;32:6812-9 pubmed publisher

Parra M, Herrera D, Jácome M, Mesa M, Rodríguez L, Guzmán C, et al. Circulating rotavirus-specific T cells have a poor functional profile. Virology. 2014;468-470:340-350 pubmed publisher

Van Hemelen D, Mahler V, Fischer G, Fae I, Reichl Leb V, Pickl W, et al. HLA class II peptide tetramers vs allergen-induced proliferation for identification of allergen-specific CD4 T cells. Allergy. 2015;70:49-58 pubmed publisher

Kvistborg P, Philips D, Kelderman S, Hageman L, Ottensmeier C, Joseph Pietras D, et al. Anti-CTLA-4 therapy broadens the melanoma-reactive CD8+ T cell response. Sci Transl Med. 2014;6:254ra128 pubmed publisher

Audia S, Rossato M, Santegoets K, Spijkers S, Wichers C, Bekker C, et al. Splenic TFH expansion participates in B-cell differentiation and antiplatelet-antibody production during immune thrombocytopenia. Blood. 2014;124:2858-66 pubmed publisher

Norton K, Han Z, Popel A, Pandey N. Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells. Onco Targets Ther. 2014;7:1571-82 pubmed publisher

Dabral N, Martha Moreno Lafont -, Sriranganathan N, Vemulapalli R. Oral immunization of mice with gamma-irradiated Brucella neotomae induces protection against intraperitoneal and intranasal challenge with virulent B. abortus 2308. PLoS ONE. 2014;9:e107180 pubmed publisher

Cho Y, Kee S, Kim T, Jin H, Kim M, Jung H, et al. Mucosal-associated invariant T cell deficiency in systemic lupus erythematosus. J Immunol. 2014;193:3891-901 pubmed publisher

Heipertz E, Davies M, Lin E, Norbury C. Prolonged antigen presentation following an acute virus infection requires direct and then cross-presentation. J Immunol. 2014;193:4169-77 pubmed publisher

Kurktschiev P, Raziorrouh B, Schraut W, Backmund M, Wächtler M, Wendtner C, et al. Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction. J Exp Med. 2014;211:2047-59 pubmed publisher

Rose S, Stansky E, Dagur P, Samsel L, Weiner E, Jahanshad A, et al. Characterization of immune cells in psoriatic adipose tissue. J Transl Med. 2014;12:258 pubmed publisher

Rabinovich S, Powell R, Lindsay R, Yuan M, Carpov A, Wilson A, et al. A novel, live-attenuated vesicular stomatitis virus vector displaying conformationally intact, functional HIV-1 envelope trimers that elicits potent cellular and humoral responses in mice. PLoS ONE. 2014;9:e106597 pubmed publisher

Rossi A, Michelini Z, Leone P, Borghi M, Blasi M, Bona R, et al. Optimization of mucosal responses after intramuscular immunization with integrase defective lentiviral vector. PLoS ONE. 2014;9:e107377 pubmed publisher

Florek N, Weinfurter J, Jegaskanda S, Brewoo J, Powell T, Young G, et al. Modified vaccinia virus Ankara encoding influenza virus hemagglutinin induces heterosubtypic immunity in macaques. J Virol. 2014;88:13418-28 pubmed publisher

Huang L, Gebreselassie N, Gagliardo L, Ruyechan M, Lee N, Lee J, et al. Eosinophil-derived IL-10 supports chronic nematode infection. J Immunol. 2014;193:4178-87 pubmed publisher

Manoharan I, Hong Y, Suryawanshi A, Angus Hill M, Sun Z, Mellor A, et al. TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation. J Immunol. 2014;193:4203-13 pubmed publisher

Sadallah S, Amicarella F, Eken C, Iezzi G, Schifferli J. Ectosomes released by platelets induce differentiation of CD4+T cells into T regulatory cells. Thromb Haemost. 2014;112:1219-29 pubmed publisher

Hayes M, Ovcinnikovs V, Smith A, Kimber I, Dearman R. The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development. PLoS ONE. 2014;9:e106955 pubmed publisher

Tousif S, Singh D, Ahmad S, Moodley P, Bhattacharyya M, Van Kaer L, et al. Isoniazid induces apoptosis of activated CD4+ T cells: implications for post-therapy tuberculosis reactivation and reinfection. J Biol Chem. 2014;289:30190-5 pubmed publisher

Wang L, Qiu J, Yu L, Hu X, Zhao P, Jiang Y. Increased numbers of CD5+CD19+CD1dhighIL-10+ Bregs, CD4+Foxp3+ Tregs, CD4+CXCR5+Foxp3+ follicular regulatory T (TFR) cells in CHB or CHC patients. J Transl Med. 2014;12:251 pubmed publisher

Santucci N, Diaz A, Bianchi E, Spinelli S, D Attilio L, Bongiovanni B, et al. Leptin does not enhance cell-mediated immune responses following mycobacterial antigen stimulation. Int J Tuberc Lung Dis. 2014;18:981-7 pubmed publisher

Ren H, Zhao S, Li W, Dong H, Zhou M, Cao M, et al. Therapeutic antitumor efficacy of B cells loaded with tumor-derived autophagasomes vaccine (DRibbles). J Immunother. 2014;37:383-93 pubmed publisher

Meher A, Johnston W, Lu G, Pope N, Bhamidipati C, Harmon D, et al. B2 cells suppress experimental abdominal aortic aneurysms. Am J Pathol. 2014;184:3130-41 pubmed publisher

Tsujimura Y, Inada H, Yoneda M, Fujita T, Matsuo K, Yasutomi Y. Effects of mycobacteria major secretion protein, Ag85B, on allergic inflammation in the lung. PLoS ONE. 2014;9:e106807 pubmed publisher

Li Z, Yang B, Zhang Y, Ma J, Chen X, Lao S, et al. Mycobacterium tuberculosis-specific memory NKT cells in patients with tuberculous pleurisy. J Clin Immunol. 2014;34:979-90 pubmed publisher

Backert I, Koralov S, Wirtz S, Kitowski V, Billmeier U, Martini E, et al. STAT3 activation in Th17 and Th22 cells controls IL-22-mediated epithelial host defense during infectious colitis. J Immunol. 2014;193:3779-91 pubmed publisher

Wei H, Nash W, Makrigiannis A, Brown M. Impaired NK-cell education diminishes resistance to murine CMV infection. Eur J Immunol. 2014;44:3273-82 pubmed publisher

Schulze B, Piehler D, Eschke M, von Buttlar H, Köhler G, Sparwasser T, et al. CD4(+) FoxP3(+) regulatory T cells suppress fatal T helper 2 cell immunity during pulmonary fungal infection. Eur J Immunol. 2014;44:3596-604 pubmed publisher

Wu L, Yun Z, Tagawa T, DE LA MAZA L, Wu M, Yu J, et al. Activation of CD1d-restricted natural killer T cells can inhibit cancer cell proliferation during chemotherapy by promoting the immune responses in murine mesothelioma. Cancer Immunol Immunother. 2014;63:1285-96 pubmed publisher

Burger M, Leung K, Bennett M, Winoto A. T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunity. elife. 2014;3: pubmed publisher

Zhou M, Zou R, Gan H, Liang Z, Li F, Lin T, et al. The effect of aging on the frequency, phenotype and cytokine production of human blood CD4?+?CXCR5?+?T follicular helper cells: comparison of aged and young subjects. Immun Ageing. 2014;11:12 pubmed publisher

Ann J, Samant M, Rhéaume C, Dumas C, Beaulieu E, Morasse A, et al. Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines. Vaccine. 2014;32:5730-9 pubmed publisher

Kobayashi T, Hamaguchi Y, Hasegawa M, Fujimoto M, Takehara K, Matsushita T. B cells promote tumor immunity against B16F10 melanoma. Am J Pathol. 2014;184:3120-9 pubmed publisher

Domínguez Nieto A, Zentella A, Moreno J, Ventura J, Pedraza S, Velázquez J. Human endotoxin tolerance is associated with enrichment of the CD14+ CD16+ monocyte subset. Immunobiology. 2015;220:147-53 pubmed publisher

Kastirr I, Maglie S, Paroni M, Alfen J, Nizzoli G, Sugliano E, et al. IL-21 is a central memory T cell-associated cytokine that inhibits the generation of pathogenic Th1/17 effector cells. J Immunol. 2014;193:3322-31 pubmed publisher

Bacher P, Kniemeyer O, Teutschbein J, Thön M, Vödisch M, Wartenberg D, et al. Identification of immunogenic antigens from Aspergillus fumigatus by direct multiparameter characterization of specific conventional and regulatory CD4+ T cells. J Immunol. 2014;193:3332-43 pubmed publisher

Reynolds B, Turner D, McPherson R, Prendergast C, Phelps R, Turner N, et al. Exposure to inflammatory cytokines selectively limits GM-CSF production by induced T regulatory cells. Eur J Immunol. 2014;44:3342-52 pubmed publisher

Davey M, Morgan M, Liuzzi A, Tyler C, Khan M, Szakmany T, et al. Microbe-specific unconventional T cells induce human neutrophil differentiation into antigen cross-presenting cells. J Immunol. 2014;193:3704-3716 pubmed publisher

Pereyra F, Heckerman D, Carlson J, Kadie C, Soghoian D, Karel D, et al. HIV control is mediated in part by CD8+ T-cell targeting of specific epitopes. J Virol. 2014;88:12937-48 pubmed publisher

Ning H, Lei H, Xu Y, Guan R, Venstrom J, Lin G, et al. Conversion of adipose-derived stem cells into natural killer-like cells with anti-tumor activities in nude mice. PLoS ONE. 2014;9:e106246 pubmed publisher

Narishige S, Kuwahara M, Shinozaki A, Okada S, Ikeda Y, Kamagata M, et al. Effects of caffeine on circadian phase, amplitude and period evaluated in cells in vitro and peripheral organs in vivo in PER2::LUCIFERASE mice. Br J Pharmacol. 2014;171:5858-69 pubmed publisher

Saksida T, Vujicic M, Nikolic I, Stojanovic I, Haegeman G, Stosic Grujicic S. Compound A, a selective glucocorticoid receptor agonist, inhibits immunoinflammatory diabetes, induced by multiple low doses of streptozotocin in mice. Br J Pharmacol. 2014;171:5898-909 pubmed publisher

Vercoulen Y, Bellutti Enders F, Meerding J, Plantinga M, Elst E, Varsani H, et al. Increased presence of FOXP3+ regulatory T cells in inflamed muscle of patients with active juvenile dermatomyositis compared to peripheral blood. PLoS ONE. 2014;9:e105353 pubmed publisher

Poh C, Howland S, Grotenbreg G, Rénia L. Damage to the blood-brain barrier during experimental cerebral malaria results from synergistic effects of CD8+ T cells with different specificities. Infect Immun. 2014;82:4854-64 pubmed publisher

Pomeshchik Y, Kidin I, Korhonen P, Savchenko E, Jaronen M, Lehtonen S, et al. Interleukin-33 treatment reduces secondary injury and improves functional recovery after contusion spinal cord injury. Brain Behav Immun. 2015;44:68-81 pubmed publisher

Tae Yu H, Youn J, Lee J, Park S, Chi H, Lee J, et al. Characterization of CD8(+)CD57(+) T cells in patients with acute myocardial infarction. Cell Mol Immunol. 2015;12:466-73 pubmed publisher

Jackson R, Worley M, Trivedi S, Ranasinghe C. Novel HIV IL-4R antagonist vaccine strategy can induce both high avidity CD8 T and B cell immunity with greater protective efficacy. Vaccine. 2014;32:5703-14 pubmed publisher

Goodier M, White M, Darboe A, Nielsen C, Goncalves A, Bottomley C, et al. Rapid NK cell differentiation in a population with near-universal human cytomegalovirus infection is attenuated by NKG2C deletions. Blood. 2014;124:2213-22 pubmed publisher

Wuest S, Mexhitaj I, Chai N, Romm E, Scheffel J, Xu B, et al. A complex role of herpes viruses in the disease process of multiple sclerosis. PLoS ONE. 2014;9:e105434 pubmed publisher

Kosmaczewska A, Ciszak L, Swierkot J, Szteblich A, Kosciow K, Frydecka I. Exogenous IL-2 controls the balance in Th1, Th17, and Treg cell distribution in patients with progressive rheumatoid arthritis treated with TNF-alpha inhibitors. Inflammation. 2015;38:765-74 pubmed publisher

Baron M, Belo R, Cathelin D, Moreira Teixeira L, Cartery C, Rondeau E, et al. Innate-like and conventional T cell populations from hemodialyzed and kidney transplanted patients are equally compromised. PLoS ONE. 2014;9:e105422 pubmed publisher

Karumuthil Melethil S, Gudi R, Johnson B, Perez N, Vasu C. Fungal β-glucan, a Dectin-1 ligand, promotes protection from type 1 diabetes by inducing regulatory innate immune response. J Immunol. 2014;193:3308-21 pubmed publisher

Haberthur K, Meyer C, Arnold N, Engelmann F, Jeske D, Messaoudi I. Intrabronchial infection of rhesus macaques with simian varicella virus results in a robust immune response in the lungs. J Virol. 2014;88:12777-92 pubmed publisher

Yu P, Bamford R, Waldmann T. IL-15-dependent CD8+ CD122+ T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+ T cells. Eur J Immunol. 2014;44:3330-41 pubmed publisher

Kim S, Chung H, Lee K, Lim J. Identification of novel epitopes from human papillomavirus type 18 E7 that can sensitize PBMCs of multiple HLA class I against human cervical cancer. J Transl Med. 2014;12:229 pubmed publisher

Lucca L, Desbois S, Ramadan A, Ben Nun A, Eisenstein M, Carrié N, et al. Bispecificity for myelin and neuronal self-antigens is a common feature of CD4 T cells in C57BL/6 mice. J Immunol. 2014;193:3267-77 pubmed publisher

Smolen K, Cai B, Fortuno E, Gelinas L, Larsen M, Speert D, et al. Single-cell analysis of innate cytokine responses to pattern recognition receptor stimulation in children across four continents. J Immunol. 2014;193:3003-3012 pubmed publisher

Comerford R, Coates C, Byrne G, Lynch S, Dunne P, Dunne M, et al. Characterisation of tissue transglutaminase-reactive T cells from patients with coeliac disease and healthy controls. Clin Immunol. 2014;154:155-63 pubmed publisher

Wang J, Guo X, Cao J, Zhang X, Zhang J, Sun D, et al. Prolonged pretreatment of mice with cholera toxin, but not isoproterenol, alleviates acute lethal systemic inflammatory response. Int Immunopharmacol. 2014;23:60-5 pubmed publisher

Wirnsberger G, Zwolanek F, Stadlmann J, Tortola L, Liu S, Perlot T, et al. Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense. Nat Genet. 2014;46:1028-33 pubmed publisher

Djikić J, Nacka Aleksić M, Pilipovic I, Stojic Vukanic Z, Bufan B, Kosec D, et al. Age-associated changes in rat immune system: lessons learned from experimental autoimmune encephalomyelitis. Exp Gerontol. 2014;58:179-97 pubmed publisher

Peng M, Huang B, Zhang Q, Fu S, Wang D, Cheng X, et al. Embelin inhibits pancreatic cancer progression by directly inducing cancer cell apoptosis and indirectly restricting IL-6 associated inflammatory and immune suppressive cells. Cancer Lett. 2014;354:407-16 pubmed publisher

John Schuster G, Hager K, Conlon T, Irmler M, Beckers J, Eickelberg O, et al. Cigarette smoke-induced iBALT mediates macrophage activation in a B cell-dependent manner in COPD. Am J Physiol Lung Cell Mol Physiol. 2014;307:L692-706 pubmed publisher

Boudousquié C, Danilo M, Pousse L, Jeevan Raj B, Angelov G, Chennupati V, et al. Differences in the transduction of canonical Wnt signals demarcate effector and memory CD8 T cells with distinct recall proliferation capacity. J Immunol. 2014;193:2784-91 pubmed publisher

Huang J, Xiao L, Gong X, Shao W, Yin Y, Liao Q, et al. Cytokine-like molecule CCDC134 contributes to CD8? T-cell effector functions in cancer immunotherapy. Cancer Res. 2014;74:5734-45 pubmed publisher

Zhang L, Zheng H, Shao H, Nian H, Zhang Y, Bai L, et al. Long-term therapeutic effects of mesenchymal stem cells compared to dexamethasone on recurrent experimental autoimmune uveitis of rats. Invest Ophthalmol Vis Sci. 2014;55:5561-71 pubmed publisher

Ahmad F, Hong H, Jäckel M, Jablonka A, Lu I, Bhatnagar N, et al. High frequencies of polyfunctional CD8+ NK cells in chronic HIV-1 infection are associated with slower disease progression. J Virol. 2014;88:12397-408 pubmed publisher

Jones R, O Connor R, Mueller S, Foley M, Szeto G, Karel D, et al. Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes. PLoS Pathog. 2014;10:e1004287 pubmed publisher

Luchting B, Rachinger Adam B, Zeitler J, Egenberger L, Möhnle P, Kreth S, et al. Disrupted TH17/Treg balance in patients with chronic low back pain. PLoS ONE. 2014;9:e104883 pubmed publisher

García Hernández U, Robledo Avila F, Alvarez Jiménez V, Rodríguez Cortés O, Wong Baeza I, Serafín López J, et al. Dialyzable leukocyte extracts activate TLR-2 on monocytes. Nat Prod Commun. 2014;9:853-6 pubmed

So J, Kim G, Song M, Lee C, Park E, Kim H, et al. 6-Methoxyflavone inhibits NFAT translocation into the nucleus and suppresses T cell activation. J Immunol. 2014;193:2772-83 pubmed publisher

Reynolds L, Harcus Y, Smith K, Webb L, Hewitson J, Ross E, et al. MyD88 signaling inhibits protective immunity to the gastrointestinal helminth parasite Heligmosomoides polygyrus. J Immunol. 2014;193:2984-93 pubmed publisher

Benkhoucha M, Molnarfi N, Dunand Sauthier I, Merkler D, Schneiter G, Bruscoli S, et al. Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells. J Immunol. 2014;193:2743-52 pubmed publisher

Zipperlen K, Gallant M, Stapleton S, Heath J, Barrett L, Grant M. Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells. Immunol Cell Biol. 2015;93:67-76 pubmed publisher

Cristofanilli M, Rosenthal H, Cymring B, Gratch D, Pagano B, Xie B, et al. Progressive multiple sclerosis cerebrospinal fluid induces inflammatory demyelination, axonal loss, and astrogliosis in mice. Exp Neurol. 2014;261:620-32 pubmed publisher

Müller J, Waldmann T, Dubois S. Loss of cytotoxicity and gain of cytokine production in murine tumor-activated NK cells. PLoS ONE. 2014;9:e102793 pubmed publisher

Hoerning A, Wilde B, Wang J, Tebbe B, Jing L, Wang X, et al. Pharmacodynamic monitoring of mammalian target of rapamycin inhibition by phosphoflow cytometric determination of p70S6 kinase activity. Transplantation. 2015;99:210-9 pubmed publisher

Yamanaka K, Umezawa Y, Yamagiwa A, Saeki H, Kondo M, Gabazza E, et al. Biologic therapy improves psoriasis by decreasing the activity of monocytes and neutrophils. J Dermatol. 2014;41:679-85 pubmed publisher

Wang X, Boyken S, Hu J, Xu X, Rimer R, Shea M, et al. Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production. Sci Signal. 2014;7:ra74 pubmed publisher

Deifl S, Kitzmuller C, Steinberger P, Himly M, Jahn Schmid B, Fischer G, et al. Differential activation of dendritic cells by toll-like receptors causes diverse differentiation of naïve CD4+ T cells from allergic patients. Allergy. 2014;69:1602-9 pubmed publisher

Ghiglione Y, Falivene J, Ruiz M, Laufer N, Socías M, Cahn P, et al. Early skewed distribution of total and HIV-specific CD8+ T-cell memory phenotypes during primary HIV infection is related to reduced antiviral activity and faster disease progression. PLoS ONE. 2014;9:e104235 pubmed publisher

Wu X, Zhang H, Xing Q, Cui J, Li J, Li Y, et al. PD-1(+) CD8(+) T cells are exhausted in tumours and functional in draining lymph nodes of colorectal cancer patients. Br J Cancer. 2014;111:1391-9 pubmed publisher

Berlin C, Kowalewski D, Schuster H, Mirza N, Walz S, Handel M, et al. Mapping the HLA ligandome landscape of acute myeloid leukemia: a targeted approach toward peptide-based immunotherapy. Leukemia. 2015;29:647-59 pubmed publisher

In J, Striz A, Bernad A, Tuma P. Serine/threonine kinase 16 and MAL2 regulate constitutive secretion of soluble cargo in hepatic cells. Biochem J. 2014;463:201-13 pubmed publisher

Lopez Granados E, Stacey M, Kienzler A, Sierro S, Willberg C, Fox C, et al. A mutation in X-linked inhibitor of apoptosis (G466X) leads to memory inflation of Epstein-Barr virus-specific T cells. Clin Exp Immunol. 2014;178:470-82 pubmed publisher

Tomescu C, Liu Q, Ross B, Yin X, Lynn K, Mounzer K, et al. A correlate of HIV-1 control consisting of both innate and adaptive immune parameters best predicts viral load by multivariable analysis in HIV-1 infected viremic controllers and chronically-infected non-controllers. PLoS ONE. 2014;9:e103209 pubmed publisher

Joetham A, Schedel M, Takeda K, Jia Y, Ashino S, Dakhama A, et al. JNK2 regulates the functional plasticity of naturally occurring T regulatory cells and the enhancement of lung allergic responses. J Immunol. 2014;193:2238-47 pubmed publisher

Jiang G, Ma S, Wei Y, Wu Y, Yu X, Liu H. The prevalence and distribution of Th17 and Tc17 cells in patients with thyroid tumor. Immunol Lett. 2014;162:68-73 pubmed publisher

Ohshima K, Kanto K, Hatakeyama K, Ide T, Wakabayashi Nakao K, Watanabe Y, et al. Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Proteomics. 2014;14:2297-306 pubmed publisher

Ji Z, Fan Z, Zhang Y, Yu R, Yang H, Zhou C, et al. Thiamine deficiency promotes T cell infiltration in experimental autoimmune encephalomyelitis: the involvement of CCL2. J Immunol. 2014;193:2157-67 pubmed publisher

Dawoodji A, Chen J, Shepherd D, Dalin F, Tarlton A, Alimohammadi M, et al. High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients. J Immunol. 2014;193:2118-26 pubmed publisher

Pathak M, Verma M, Srivastava M, Misra Bhattacharya S. Wolbachia endosymbiont of Brugia malayi elicits a T helper type 17-mediated pro-inflammatory immune response through Wolbachia surface protein. Immunology. 2015;144:231-44 pubmed publisher

Said A, Bock S, Müller G, Weindl G. Inflammatory conditions distinctively alter immunological functions of Langerhans-like cells and dendritic cells in vitro. Immunology. 2015;144:218-30 pubmed publisher

Jung I, Choi J, Jin J, Jeong S, Jeon S, Lim C, et al. CD137-inducing factors from T cells and macrophages accelerate the destabilization of atherosclerotic plaques in hyperlipidemic mice. FASEB J. 2014;28:4779-91 pubmed publisher

Wu L, Wen H, Zhou Y, Yu H, Liu Y, Bai L, et al. Activation of the liver X receptor inhibits Th17 and Th1 responses in Behcet's disease and Vogt-Koyanagi-Harada disease. Curr Mol Med. 2014;14:712-22 pubmed

Saha A, Biswas A, Srivastav S, Mukherjee M, Das P, Ukil A. Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis. J Immunol. 2014;193:2330-9 pubmed publisher

Riou C, Gray C, Lugongolo M, Gwala T, Kiravu A, Deniso P, et al. A subset of circulating blood mycobacteria-specific CD4 T cells can predict the time to Mycobacterium tuberculosis sputum culture conversion. PLoS ONE. 2014;9:e102178 pubmed publisher

Nusser A, Nuber N, Wirz O, Rolink H, Andersson J, Rolink A. The development of autoimmune features in aging mice is closely associated with alterations of the peripheral CD4⁺ T-cell compartment. Eur J Immunol. 2014;44:2893-902 pubmed publisher

Park K, Park H, Shin K, Lee M. Multiple treatments with L-3,4-dihydroxyphenylalanine modulate dopamine biosynthesis and neurotoxicity through the protein kinase A-transient extracellular signal-regulated kinase and exchange protein activation by cyclic AMP-sustained extracellular . J Neurosci Res. 2014;92:1746-56 pubmed publisher

Ota K, Yamagishi S, Kim M, Dambaeva S, Gilman Sachs A, Beaman K, et al. Elevation of soluble form of receptor for advanced glycation end products (sRAGE) in recurrent pregnancy losses (RPL): possible participation of RAGE in RPL. Fertil Steril. 2014;102:782-9 pubmed publisher

Korner C, Granoff M, Amero M, Sirignano M, Vaidya S, Jost S, et al. Increased frequency and function of KIR2DL1-3⁺ NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes. Eur J Immunol. 2014;44:2938-48 pubmed publisher

Pentcheva Hoang T, Simpson T, Montalvo Ortiz W, Allison J. Cytotoxic T lymphocyte antigen-4 blockade enhances antitumor immunity by stimulating melanoma-specific T-cell motility. Cancer Immunol Res. 2014;2:970-80 pubmed publisher

Han X, Yang Q, Lin L, Xu C, Zheng C, Chen X, et al. Interleukin-17 enhances immunosuppression by mesenchymal stem cells. Cell Death Differ. 2014;21:1758-68 pubmed publisher

Whitney P, Bär E, Osorio F, Rogers N, Schraml B, Deddouche S, et al. Syk signaling in dendritic cells orchestrates innate resistance to systemic fungal infection. PLoS Pathog. 2014;10:e1004276 pubmed publisher

Thackray L, Shrestha B, Richner J, Miner J, Pinto A, Lazear H, et al. Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection. J Virol. 2014;88:11007-21 pubmed publisher

Dadaglio G, Fayolle C, Zhang X, Ryffel B, Oberkampf M, Félix T, et al. Antigen targeting to CD11b+ dendritic cells in association with TLR4/TRIF signaling promotes strong CD8+ T cell responses. J Immunol. 2014;193:1787-98 pubmed publisher

Singh A, Thirumalapura N. Early induction of interleukin-10 limits antigen-specific CD4⁺ T cell expansion, function, and secondary recall responses during persistent phagosomal infection. Infect Immun. 2014;82:4092-103 pubmed publisher

Kylaniemi M, Kaukonen R, Myllyviita J, Rasool O, Lahesmaa R. The regulation and role of c-FLIP in human Th cell differentiation. PLoS ONE. 2014;9:e102022 pubmed publisher

Lenhart K, Becherer A, Li J, Xiao X, McNally E, Mack C, et al. GRAF1 promotes ferlin-dependent myoblast fusion. Dev Biol. 2014;393:298-311 pubmed publisher

Fouka E, Lamprianidou E, Arvanitidis K, Filidou E, Kolios G, Miltiades P, et al. Low-dose clarithromycin therapy modulates Th17 response in non-cystic fibrosis bronchiectasis patients. Lung. 2014;192:849-55 pubmed publisher

Cheng L, Du X, Wang Z, Ju J, Jia M, Huang Q, et al. Hyper-IL-15 suppresses metastatic and autochthonous liver cancer by promoting tumour-specific CD8+ T cell responses. J Hepatol. 2014;61:1297-303 pubmed publisher

Ni P, Solomon B, Hsieh C, Allen P, Morris G. The ability to rearrange dual TCRs enhances positive selection, leading to increased Allo- and Autoreactive T cell repertoires. J Immunol. 2014;193:1778-86 pubmed publisher

Duewell P, Steger A, Lohr H, Bourhis H, Hoelz H, Kirchleitner S, et al. RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8(+) T cells. Cell Death Differ. 2014;21:1825-37 pubmed publisher

INGE L, Friel J, Richer A, Fowler A, Whitsett T, Smith M, et al. LKB1 inactivation sensitizes non-small cell lung cancer to pharmacological aggravation of ER stress. Cancer Lett. 2014;352:187-95 pubmed publisher

Floderer M, Prchal Murphy M, Vizzardelli C. Dendritic cell-secreted lipocalin2 induces CD8+ T-cell apoptosis, contributes to T-cell priming and leads to a TH1 phenotype. PLoS ONE. 2014;9:e101881 pubmed publisher

Kistowska M, Meier B, Proust T, Feldmeyer L, Cozzio A, Kuendig T, et al. Propionibacterium acnes promotes Th17 and Th17/Th1 responses in acne patients. J Invest Dermatol. 2015;135:110-118 pubmed publisher

Yi Z, Stunz L, Lin W, Bishop G. TRAF3 regulates homeostasis of CD8+ central memory T cells. PLoS ONE. 2014;9:e102120 pubmed publisher

Jackson S, Mason G, Okecha G, Sissons J, Wills M. Diverse specificities, phenotypes, and antiviral activities of cytomegalovirus-specific CD8+ T cells. J Virol. 2014;88:10894-908 pubmed publisher

Cantor J. CD98 is a potential target for ablating B cell clonal expansion and autoantibody in multiple sclerosis. J Neuroimmunol. 2014;274:230-3 pubmed publisher

Khan M, Coleman J, Vernatter J, Varshney A, Dufaud C, Pirofski L. An ahemolytic pneumolysin of Streptococcus pneumoniae manipulates human innate and CD4⁺ T-cell responses and reduces resistance to colonization in mice in a serotype-independent manner. J Infect Dis. 2014;210:1658-69 pubmed publisher

Wolf A, Strauman M, Mozdzanowska K, Williams K, Osborne L, Shen H, et al. Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease. Virology. 2014;462-463:254-65 pubmed publisher

Morrison M, Keane C, Quinn L, Kelly A, O Farrelly C, Bergin C, et al. IFNL cytokines do not modulate human or murine NK cell functions. Hum Immunol. 2014;75:996-1000 pubmed publisher

Boyoglu Barnum S, Chirkova T, Todd S, Barnum T, Gaston K, Jorquera P, et al. Prophylaxis with a respiratory syncytial virus (RSV) anti-G protein monoclonal antibody shifts the adaptive immune response to RSV rA2-line19F infection from Th2 to Th1 in BALB/c mice. J Virol. 2014;88:10569-83 pubmed publisher

Lopez M, Palmer B, Lawrence D. Naïve T cells, unconventional NK and NKT cells, and highly responsive monocyte-derived macrophages characterize human cord blood. Immunobiology. 2014;219:756-65 pubmed publisher

Kim S, Sohn S, Won A, Kim H, Moon A. Identification of noninvasive biomarkers for nephrotoxicity using HK-2 human kidney epithelial cells. Toxicol Sci. 2014;140:247-58 pubmed publisher

Arantes Costa F, Grund L, Martins M, Lima C. Airborne pollutant ROFA enhances the allergic airway inflammation through direct modulation of dendritic cells in an uptake-dependent mechanism. Int Immunopharmacol. 2014;22:9-20 pubmed publisher

Xie L, Chen J, McMickle A, Awar N, Nady S, Sredni B, et al. The immunomodulator AS101 suppresses production of inflammatory cytokines and ameliorates the pathogenesis of experimental autoimmune encephalomyelitis. J Neuroimmunol. 2014;273:31-41 pubmed publisher

Morishima S, Nakamura S, Yamamoto K, Miyauchi H, Kagami Y, Kinoshita T, et al. Increased T-cell responses to Epstein-Barr virus with high viral load in patients with Epstein-Barr virus-positive diffuse large B-cell lymphoma. Leuk Lymphoma. 2015;56:1072-8 pubmed publisher

Wang F, Zha W, Zhang J, Li S, Wang H, Ye L, et al. Complement C3a binding to its receptor as a negative modulator of Th2 response in liver injury in trichloroethylene-sensitized mice. Toxicol Lett. 2014;229:229-39 pubmed publisher

Diana J, Lehuen A. Macrophages and ?-cells are responsible for CXCR2-mediated neutrophil infiltration of the pancreas during autoimmune diabetes. EMBO Mol Med. 2014;6:1090-104 pubmed publisher

Lewis N, Patnaude L, Pelletier J, Souza D, Lukas S, King F, et al. A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo. PLoS ONE. 2014;9:e100883 pubmed publisher

Ray S, Fanti J, Macedo D, Larsen M. LIM kinase regulation of cytoskeletal dynamics is required for salivary gland branching morphogenesis. Mol Biol Cell. 2014;25:2393-407 pubmed publisher

Wei R, Dong L, Xiao Q, Sun D, Li X, Nian H. Engagement of Toll-like receptor 2 enhances interleukin (IL)-17(+) autoreactive T cell responses via p38 mitogen-activated protein kinase signalling in dendritic cells. Clin Exp Immunol. 2014;178:353-63 pubmed publisher

Celis Gutierrez J, Boyron M, Walzer T, Pandolfi P, Jonjic S, Olive D, et al. Dok1 and Dok2 proteins regulate natural killer cell development and function. EMBO J. 2014;33:1928-40 pubmed publisher

Li C, Jiang S, Liu S, Lykken E, Zhao L, Sevilla J, et al. MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation. Proc Natl Acad Sci U S A. 2014;111:E2807-16 pubmed publisher

Du J, Lopez Verges S, Pitcher B, Johnson J, Jung S, Zhou L, et al. CALGB 150905 (Alliance): rituximab broadens the antilymphoma response by activating unlicensed NK cells. Cancer Immunol Res. 2014;2:878-89 pubmed publisher

Yamaji Y, Nakayama T. Recombinant measles viruses expressing respiratory syncytial virus proteins induced virus-specific CTL responses in cotton rats. Vaccine. 2014;32:4529-36 pubmed publisher

Mycko M, Sliwinska B, Cichalewska M, Cwiklinska H, Raine C, Selmaj K. Brain glycolipids suppress T helper cells and inhibit autoimmune demyelination. J Neurosci. 2014;34:8646-58 pubmed publisher

Jiao Y, Wang X, Zhang T, Sun L, Wang R, Li W, et al. Regulatory B cells correlate with HIV disease progression. Microbiol Immunol. 2014;58:449-55 pubmed publisher

Bouma G, Carter N, Recher M, Malinova D, Adriani M, Notarangelo L, et al. Exacerbated experimental arthritis in Wiskott-Aldrich syndrome protein deficiency: modulatory role of regulatory B cells. Eur J Immunol. 2014;44:2692-702 pubmed publisher

Matangkasombut P, Chan In W, Opasawaschai A, Pongchaikul P, Tangthawornchaikul N, Vasanawathana S, et al. Invariant NKT cell response to dengue virus infection in human. PLoS Negl Trop Dis. 2014;8:e2955 pubmed publisher

Zhao Z, Jiang X, Kang C, Xiao Y, Hou C, Yu J, et al. Blockade of the T cell immunoglobulin and mucin domain protein 3 pathway exacerbates sepsis-induced immune deviation and immunosuppression. Clin Exp Immunol. 2014;178:279-91 pubmed publisher

Vasiliou J, Lui S, Walker S, Chohan V, Xystrakis E, Bush A, et al. Vitamin D deficiency induces Th2 skewing and eosinophilia in neonatal allergic airways disease. Allergy. 2014;69:1380-9 pubmed publisher

Okeke E, Okwor I, Uzonna J. Regulatory T cells restrain CD4+ T cells from causing unregulated immune activation and hypersensitivity to lipopolysaccharide challenge. J Immunol. 2014;193:655-62 pubmed publisher

Madhavi V, Wren L, Center R, Gonelli C, Winnall W, Parsons M, et al. Breadth of HIV-1 Env-specific antibody-dependent cellular cytotoxicity: relevance to global HIV vaccine design. AIDS. 2014;28:1859-70 pubmed publisher

Takeda A, Hasegawa E, Fukuhara T, Hirakawa S, Yamada H, Yang Y, et al. EBI3 is pivotal for the initiation of experimental autoimmune uveitis. Exp Eye Res. 2014;125:107-13 pubmed publisher

Voo K, Bover L, Harline M, Weng J, Sugimoto N, Liu Y. Targeting of TLRs inhibits CD4+ regulatory T cell function and activates lymphocytes in human peripheral blood mononuclear cells. J Immunol. 2014;193:627-34 pubmed publisher

Lykken J, DiLillo D, Weimer E, Roser Page S, Heise M, Grayson J, et al. Acute and chronic B cell depletion disrupts CD4+ and CD8+ T cell homeostasis and expansion during acute viral infection in mice. J Immunol. 2014;193:746-56 pubmed publisher

Shen Y, Nagpal P, Hay J, Sauthoff H. A novel cell-penetrating peptide to facilitate intercellular transport of fused proteins. J Control Release. 2014;188:44-52 pubmed publisher

Friedman R, Lindsay R, Lilly J, Nguyen V, Sorensen C, Jacobelli J, et al. An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function. Proc Natl Acad Sci U S A. 2014;111:9223-8 pubmed publisher

Brezar V, Ruffin N, Levy Y, Seddiki N. A highly relevant and efficient single step method for simultaneous depletion and isolation of human regulatory T cells in a clinical setting. J Immunol Methods. 2014;411:70-5 pubmed publisher

Mbow M, de Jong S, Meurs L, Mboup S, Dieye T, Polman K, et al. Changes in immunological profile as a function of urbanization and lifestyle. Immunology. 2014;143:569-77 pubmed publisher

Kaczmarek J, Homsi Y, van Üüm J, Metzger C, Knolle P, Kolanus W, et al. Liver sinusoidal endothelial cell-mediated CD8 T cell priming depends on co-inhibitory signal integration over time. PLoS ONE. 2014;9:e99574 pubmed publisher

Liu C, Wang H, Yu S, Jin R, Tang H, Liu Y, et al. Id1 expression promotes T regulatory cell differentiation by facilitating TCR costimulation. J Immunol. 2014;193:663-672 pubmed publisher

Derycke L, Eyerich S, Van Crombruggen K, Perez Novo C, Holtappels G, DeRuyck N, et al. Mixed T helper cell signatures in chronic rhinosinusitis with and without polyps. PLoS ONE. 2014;9:e97581 pubmed publisher

Bonduelle O, Carrat F, Luyt C, Leport C, Mosnier A, Benhabilès N, et al. Characterization of pandemic influenza immune memory signature after vaccination or infection. J Clin Invest. 2014;124:3129-36 pubmed publisher

Araujo L, Fert I, Jouhault Q, Labroquère K, Andrieu M, Chiocchia G, et al. Increased production of interleukin-17 over interleukin-10 by treg cells implicates inducible costimulator molecule in experimental spondyloarthritis. Arthritis Rheumatol. 2014;66:2412-22 pubmed publisher

Commandeur S, Coppola M, Dijkman K, Friggen A, van Meijgaarden K, van den Eeden S, et al. Clonal analysis of the T-cell response to in vivo expressed Mycobacterium tuberculosis protein Rv2034, using a CD154 expression based T-cell cloning method. PLoS ONE. 2014;9:e99203 pubmed publisher

Zhang L, Zhang S, Ruan S, Zhang Q, He Q, Gao H. Lapatinib-incorporated lipoprotein-like nanoparticles: preparation and a proposed breast cancer-targeting mechanism. Acta Pharmacol Sin. 2014;35:846-52 pubmed publisher

Payne T, Blackinton J, Frisbee A, Pickeral J, Sawant S, Vandergrift N, et al. Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition. J Virol. 2014;88:9514-28 pubmed publisher

Liu C, Wang S, Kao C, Hsieh R, Chang M, Chang Y, et al. B cells facilitate platelet production mediated by cytokines in patients with essential thrombocythaemia. Thromb Haemost. 2014;112:537-50 pubmed publisher

Garcia K, Sun Z, Mattson E, Li L, Smyth K, Xiao Z. IL-12 is required for mTOR regulation of memory CTLs during viral infection. Genes Immun. 2014;15:413-23 pubmed publisher

Maier Moore J, Horton C, Mathews S, Confer A, Lawrence C, Pan Z, et al. Interleukin-6 deficiency corrects nephritis, lymphocyte abnormalities, and secondary Sjögren's syndrome features in lupus-prone Sle1.Yaa mice. Arthritis Rheumatol. 2014;66:2521-31 pubmed publisher

Duhen T, Campbell D. IL-1β promotes the differentiation of polyfunctional human CCR6+CXCR3+ Th1/17 cells that are specific for pathogenic and commensal microbes. J Immunol. 2014;193:120-9 pubmed publisher

Spidale N, Wang B, Tisch R. Cutting edge: Antigen-specific thymocyte feedback regulates homeostatic thymic conventional dendritic cell maturation. J Immunol. 2014;193:21-5 pubmed publisher

Han Y, Ye A, Bi L, Wu J, Yu K, Zhang S. Th17 cells and interleukin-17 increase with poor prognosis in patients with acute myeloid leukemia. Cancer Sci. 2014;105:933-42 pubmed publisher

Wang C, Tian Y, Ye Z, Kijlstra A, Zhou Y, Yang P. Decreased interleukin 27 expression is associated with active uveitis in Behçet's disease. Arthritis Res Ther. 2014;16:R117 pubmed publisher

Kolypetri P, Carayanniotis K, Rahman S, Georghiou P, Magafa V, Cordopatis P, et al. The thyroxine-containing thyroglobulin peptide (aa 2549-2560) is a target epitope in iodide-accelerated spontaneous autoimmune thyroiditis. J Immunol. 2014;193:96-101 pubmed publisher

Jegaskanda S, Ahn S, Skinner N, Thompson A, Ngyuen T, Holmes J, et al. Downregulation of interleukin-18-mediated cell signaling and interferon gamma expression by the hepatitis B virus e antigen. J Virol. 2014;88:10412-20 pubmed publisher

Liao L, Zhang M, Liu H, Zhang X, Xie Z, Zhang Z, et al. Subchronic toxicity and immunotoxicity of MeO-PEG-poly(D,L-lactic-co-glycolic acid)-PEG-OMe triblock copolymer nanoparticles delivered intravenously into rats. Nanotechnology. 2014;25:245705 pubmed publisher

Chen S, Xuan J, Couch L, Iyer A, Wu Y, Li Q, et al. Sertraline induces endoplasmic reticulum stress in hepatic cells. Toxicology. 2014;322:78-88 pubmed publisher

Jones C, Pagni P, Fousteri G, Sachithanantham S, Dave A, Rodríguez Calvo T, et al. Regulatory T cells control diabetes without compromising acute anti-viral defense. Clin Immunol. 2014;153:298-307 pubmed publisher

Cao L, Wu C, Shi H, Gong Z, Zhang E, Wang H, et al. Coexistence of hepatitis B virus quasispecies enhances viral replication and the ability to induce host antibody and cellular immune responses. J Virol. 2014;88:8656-66 pubmed publisher

Xue Z, Li W, Wang H, Huang B, Ge Z, Gu C, et al. ZSTK474, a novel PI3K inhibitor, modulates human CD14+ monocyte-derived dendritic cell functions and suppresses experimental autoimmune encephalomyelitis. J Mol Med (Berl). 2014;92:1057-68 pubmed publisher

Grille S, Moreno M, Bascuas T, Marqués J, Muñoz N, Lens D, et al. Salmonella enterica serovar Typhimurium immunotherapy for B-cell lymphoma induces broad anti-tumour immunity with therapeutic effect. Immunology. 2014;143:428-37 pubmed publisher

Lepore M, Kalinichenko A, Kalinicenko A, Colone A, Paleja B, Singhal A, et al. Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCR? repertoire. Nat Commun. 2014;5:3866 pubmed publisher

Zhou M, Liu R, Su D, Feng X, Li X. TL1A increased the differentiation of peripheral Th17 in rheumatoid arthritis. Cytokine. 2014;69:125-30 pubmed publisher

Todros Dawda I, Kveberg L, Vaage J, Inngjerdingen M. The tetraspanin CD53 modulates responses from activating NK cell receptors, promoting LFA-1 activation and dampening NK cell effector functions. PLoS ONE. 2014;9:e97844 pubmed publisher

Heesch K, Raczkowski F, Schumacher V, Hünemörder S, Panzer U, Mittrücker H. The function of the chemokine receptor CXCR6 in the T cell response of mice against Listeria monocytogenes. PLoS ONE. 2014;9:e97701 pubmed publisher

Eyrich M, Schreiber S, Rachor J, Krauss J, Pauwels F, Hain J, et al. Development and validation of a fully GMP-compliant production process of autologous, tumor-lysate-pulsed dendritic cells. Cytotherapy. 2014;16:946-64 pubmed publisher

Neubert K, Lehmann C, Heger L, Baranska A, Staedtler A, Buchholz V, et al. Antigen delivery to CD11c+CD8- dendritic cells induces protective immune responses against experimental melanoma in mice in vivo. J Immunol. 2014;192:5830-8 pubmed publisher

Das R, Tripathy A. Increased expressions of NKp44, NKp46 on NK/NKT-like cells are associated with impaired cytolytic function in self-limiting hepatitis E infection. Med Microbiol Immunol. 2014;203:303-14 pubmed publisher

Brant F, Miranda A, Esper L, Rodrigues D, Kangussu L, Bonaventura D, et al. Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection. Infect Immun. 2014;82:3127-40 pubmed publisher

Li J, Jia M, Liu Y, She W, Li L, Wang J, et al. Telbivudine therapy may shape CD4(+) T-cell response to prevent liver fibrosis in patients with chronic hepatitis B. Liver Int. 2015;35:834-45 pubmed publisher

Quakkelaar E, Fransen M, van Maren W, Vaneman J, Loof N, van Heiningen S, et al. IgG-mediated anaphylaxis to a synthetic long peptide vaccine containing a B cell epitope can be avoided by slow-release formulation. J Immunol. 2014;192:5813-20 pubmed publisher

Xia Y, Chen B, Shao X, Xiao W, Qian L, Ding Y, et al. Treatment with a fusion protein of the extracellular domains of NKG2D to IL-15 retards colon cancer growth in mice. J Immunother. 2014;37:257-66 pubmed publisher

Massot B, Michel M, Diem S, Ohnmacht C, Latour S, Dy M, et al. TLR-induced cytokines promote effective proinflammatory natural Th17 cell responses. J Immunol. 2014;192:5635-42 pubmed publisher

Macleod A, Rudolph R, Corriden R, Ye I, Garijo O, Havran W. Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair. J Immunol. 2014;192:5695-702 pubmed publisher

Thaxton J, Liu B, Zheng P, Liu Y, Li Z. Deletion of CD24 impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells. J Immunol. 2014;192:5679-86 pubmed publisher

Serrano Pertierra E, Cernuda Morollón E, Brdicka T, Hoøejši V, Lopez Larrea C. L-plastin is involved in NKG2D recruitment into lipid rafts and NKG2D-mediated NK cell migration. J Leukoc Biol. 2014;96:437-45 pubmed publisher

Tanaka M, Mun S, Harada A, Ohkawa Y, Inagaki A, Sano S, et al. Hsc70 contributes to cancer cell survival by preventing Rab1A degradation under stress conditions. PLoS ONE. 2014;9:e96785 pubmed publisher

Zhang Y, Mena P, Romanov G, Bliska J. Effector CD8+ T cells are generated in response to an immunodominant epitope in type III effector YopE during primary Yersinia pseudotuberculosis infection. Infect Immun. 2014;82:3033-44 pubmed publisher

Srinivasa B, Fixman E, Ward B. Inhibition of STAT6 during vaccination with formalin-inactivated RSV prevents induction of Th2-cell-biased airway disease. Eur J Immunol. 2014;44:2349-59 pubmed publisher

Mittal R, Wagener M, Breed E, Liang Z, Yoseph B, Burd E, et al. Phenotypic T cell exhaustion in a murine model of bacterial infection in the setting of pre-existing malignancy. PLoS ONE. 2014;9:e93523 pubmed publisher

Eisenbacher J, Schrezenmeier H, Jahrsdorfer B, Kaltenmeier C, Rojewski M, Yildiz T, et al. S100A4 and uric acid promote mesenchymal stromal cell induction of IL-10+/IDO+ lymphocytes. J Immunol. 2014;192:6102-10 pubmed publisher

Jeanbart L, Ballester M, de Titta A, Corthesy P, Romero P, Hubbell J, et al. Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes. Cancer Immunol Res. 2014;2:436-47 pubmed publisher

Joseph E, Green P, Levine J. ATP release mechanisms of endothelial cell-mediated stimulus-dependent hyperalgesia. J Pain. 2014;15:771-7 pubmed publisher

Jiang Y, Li M, Zhang Z, Gong T, Sun X. Enhancement of nasal HIV vaccination with adenoviral vector-based nanocomplexes using mucoadhesive and DC-targeting adjuvants. Pharm Res. 2014;31:2748-61 pubmed publisher

Hu Y, Dong C, Yue Y, Xiong S. In vivo delivery of interleukin-35 relieves coxsackievirus-B3-induced viral myocarditis by inhibiting Th17 cells. Arch Virol. 2014;159:2411-9 pubmed publisher

Li S, Joseph C, Becourt C, Klibi J, Luce S, Dubois Laforgue D, et al. Potential role of IL-17-producing iNKT cells in type 1 diabetes. PLoS ONE. 2014;9:e96151 pubmed publisher

Criado G, Risco A, Alsina Beauchamp D, Pérez Lorenzo M, Escós A, Cuenda A. Alternative p38 MAPKs are essential for collagen-induced arthritis. Arthritis Rheumatol. 2014;66:1208-17 pubmed publisher

Chu D, Mohammed Ali Z, Jiménez Saiz R, Walker T, Goncharova S, Llop Guevara A, et al. T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes. Mucosal Immunol. 2014;7:1395-404 pubmed publisher

Thoens C, Berger C, Trippler M, Siemann H, Lutterbeck M, Broering R, et al. KIR2DL3⁺NKG2A⁻ natural killer cells are associated with protection from productive hepatitis C virus infection in people who inject drugs. J Hepatol. 2014;61:475-81 pubmed publisher

Hsu H, Jansen L, Lawand M, Kim J, Pérez Arroyo A, Culina S, et al. Endoplasmic reticulum targeting alters regulation of expression and antigen presentation of proinsulin. J Immunol. 2014;192:4957-66 pubmed publisher

Redmond W, Linch S, Kasiewicz M. Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity. Cancer Immunol Res. 2014;2:142-53 pubmed publisher

Turqueti Neves A, Otte M, Prazeres da Costa O, Höpken U, Lipp M, Buch T, et al. B-cell-intrinsic STAT6 signaling controls germinal center formation. Eur J Immunol. 2014;44:2130-8 pubmed publisher

Akeus P, Langenes V, von Mentzer A, Yrlid U, Sjoling A, Saksena P, et al. Altered chemokine production and accumulation of regulatory T cells in intestinal adenomas of APC(Min/+) mice. Cancer Immunol Immunother. 2014;63:807-19 pubmed publisher

Tsukamoto H, Nishikata R, Senju S, Nishimura Y. Myeloid-derived suppressor cells attenuate TH1 development through IL-6 production to promote tumor progression. Cancer Immunol Res. 2013;1:64-76 pubmed publisher

Ziomek G, Cheraghi Zanjani P, Arman D, van Breemen C, Esfandiarei M. Calcium regulation in aortic smooth muscle cells during the initial phase of tunicamycin-induced endo/sarcoplasmic reticulum stress. Eur J Pharmacol. 2014;735:86-96 pubmed publisher

Kverka M, Hartley J, Chu T, Yang J, Heidchen R, Kopecek J. Immunogenicity of coiled-coil based drug-free macromolecular therapeutics. Biomaterials. 2014;35:5886-96 pubmed publisher

Black C, Armstrong T, Jaffee E. Apoptosis-regulated low-avidity cancer-specific CD8(+) T cells can be rescued to eliminate HER2/neu-expressing tumors by costimulatory agonists in tolerized mice. Cancer Immunol Res. 2014;2:307-19 pubmed publisher

Rodriguez Garcia M, Barr F, Crist S, Fahey J, Wira C. Phenotype and susceptibility to HIV infection of CD4+ Th17 cells in the human female reproductive tract. Mucosal Immunol. 2014;7:1375-85 pubmed publisher

Kim H, Kwon H, Kim G, Cho M, Yoon S, Davies A, et al. Attenuation of natural killer cell functions by capsaicin through a direct and TRPV1-independent mechanism. Carcinogenesis. 2014;35:1652-60 pubmed publisher

da Silva Souza H, Lira M, Costa Junior H, da Cruz C, Vasconcellos J, Mendes A, et al. Inhibitors of the 5-lipoxygenase arachidonic acid pathway induce ATP release and ATP-dependent organic cation transport in macrophages. Biochim Biophys Acta. 2014;1838:1967-77 pubmed publisher

Kukkonen S, Martinez Viedma M, Kim N, Manrique M, Aldovini A. HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells. Retrovirology. 2014;11:30 pubmed publisher

Freeman B, Meyer C, Slifka M. Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions. J Virol. 2014;88:7474-84 pubmed publisher

Turner M, Isse K, Fischer D, Turnquist H, Morel P. Low TCR signal strength induces combined expansion of Th2 and regulatory T cell populations that protect mice from the development of type 1 diabetes. Diabetologia. 2014;57:1428-36 pubmed publisher

Lindenberg J, van de Ven R, Oosterhoff D, Sombroek C, Lougheed S, Stam A, et al. Induction of dendritic cell maturation in the skin microenvironment by soluble factors derived from colon carcinoma. Hum Vaccin Immunother. 2014;10:1622-32 pubmed publisher

Lepse N, Abdulahad W, Rutgers A, Kallenberg C, Stegeman C, Heeringa P. Altered B cell balance, but unaffected B cell capacity to limit monocyte activation in anti-neutrophil cytoplasmic antibody-associated vasculitis in remission. Rheumatology (Oxford). 2014;53:1683-92 pubmed publisher

Todd S, Pepper R, Draibe J, Tanna A, Pusey C, Mauri C, et al. Regulatory B cells are numerically but not functionally deficient in anti-neutrophil cytoplasm antibody-associated vasculitis. Rheumatology (Oxford). 2014;53:1693-703 pubmed publisher

Quinan B, Flesch I, Pinho T, Coelho F, Tscharke D, da Fonseca F. An intact signal peptide on dengue virus E protein enhances immunogenicity for CD8(+) T cells and antibody when expressed from modified vaccinia Ankara. Vaccine. 2014;32:2972-9 pubmed publisher

Riedl P, Reiser M, Stifter K, Krieger J, Schirmbeck R. Differential presentation of endogenous and exogenous hepatitis B surface antigens influences priming of CD8(+) T cells in an epitope-specific manner. Eur J Immunol. 2014;44:1981-91 pubmed publisher

Miao H, Choi B, Suryadevara C, Sanchez Perez L, Yang S, De Leon G, et al. EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma. PLoS ONE. 2014;9:e94281 pubmed publisher

Wang H, Ying H, Wang S, Gu X, Weng Y, Peng W, et al. Imbalance of peripheral blood Th17 and Treg responses in patients with chronic obstructive pulmonary disease. Clin Respir J. 2015;9:330-41 pubmed publisher

Zhao K, Zhao D, Huang D, Yin L, Chen C, Pan B, et al. Interleukin-22 aggravates murine acute graft-versus-host disease by expanding effector T cell and reducing regulatory T cell. J Interferon Cytokine Res. 2014;34:707-15 pubmed publisher

Diao H, He J, Zheng Q, Chen J, Cui G, Wei Y, et al. A possible role for NKT-like cells in patients with chronic hepatitis B during telbivudine treatment. Immunol Lett. 2014;160:65-71 pubmed publisher

Balabanova S, Holmberg C, Steele I, Ebrahimi B, Rainbow L, Burdyga T, et al. The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression. Carcinogenesis. 2014;35:1798-806 pubmed publisher

Ma C, Liu Z, Li W, Qian X, Zhang S, Gao X, et al. FbaA- and M protein-based multi-epitope vaccine elicits strong protective immune responses against group A streptococcus in mouse model. Microbes Infect. 2014;16:409-18 pubmed publisher

Hasegawa H, Forte C, Barber I, Turnbaugh S, Stoops J, Shen M, et al. Modulation of in vivo IgG crystallization in the secretory pathway by heavy chain isotype class switching and N-linked glycosylation. Biochim Biophys Acta. 2014;1843:1325-38 pubmed publisher

Martínez M, Snapp E, Perumal G, Macaluso F, Kielian M. Imaging the alphavirus exit pathway. J Virol. 2014;88:6922-33 pubmed publisher

Piper C, Pesenacker A, Bending D, Thirugnanabalan B, Varsani H, Wedderburn L, et al. T cell expression of granulocyte-macrophage colony-stimulating factor in juvenile arthritis is contingent upon Th17 plasticity. Arthritis Rheumatol. 2014;66:1955-60 pubmed publisher

Ito S, Bollard C, Carlsten M, Melenhorst J, Biancotto A, Wang E, et al. Ultra-low dose interleukin-2 promotes immune-modulating function of regulatory T cells and natural killer cells in healthy volunteers. Mol Ther. 2014;22:1388-1395 pubmed publisher

Wijewardana V, Bouwer A, Brown K, Liu X, Barratt Boyes S. Accumulation of functionally immature myeloid dendritic cells in lymph nodes of rhesus macaques with acute pathogenic simian immunodeficiency virus infection. Immunology. 2014;143:146-54 pubmed publisher

Wengerter B, Katakowski J, Rosenberg J, Park C, Almo S, Palliser D, et al. Aptamer-targeted antigen delivery. Mol Ther. 2014;22:1375-1387 pubmed publisher

Lee J, Ryu J, Jeong H, Kim M, Wee W. In Vitro Immunomodulatory Effects of Human Corneal Stromal Cells on Human Th17 Cells. Ocul Immunol Inflamm. 2015;23:194-204 pubmed publisher

Kundu R, Chain B, Coussens A, Khoo B, Noursadeghi M. Regulation of CYP27B1 and CYP24A1 hydroxylases limits cell-autonomous activation of vitamin D in dendritic cells. Eur J Immunol. 2014;44:1781-90 pubmed publisher

Snelgrove R, Gregory L, Peiró T, Akthar S, Campbell G, Walker S, et al. Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbations. J Allergy Clin Immunol. 2014;134:583-592.e6 pubmed publisher

van der Geest K, Abdulahad W, Chalan P, Rutgers A, Horst G, Huitema M, et al. Disturbed B cell homeostasis in newly diagnosed giant cell arteritis and polymyalgia rheumatica. Arthritis Rheumatol. 2014;66:1927-38 pubmed publisher

Bhuiyan S, Sayeed A, Khanam F, Leung D, Rahman Bhuiyan T, Sheikh A, et al. Cellular and cytokine responses to Salmonella enterica serotype Typhi proteins in patients with typhoid fever in Bangladesh. Am J Trop Med Hyg. 2014;90:1024-30 pubmed publisher

Pan Q, Yu Y, Tang Z, Xi M, Jiang H, Xun Y, et al. Increased levels of IL-21 responses are associated with the severity of liver injury in patients with chronic active hepatitis B. J Viral Hepat. 2014;21:e78-88 pubmed publisher

Van Maele L, Carnoy C, Cayet D, Ivanov S, Porte R, Deruy E, et al. Activation of Type 3 innate lymphoid cells and interleukin 22 secretion in the lungs during Streptococcus pneumoniae infection. J Infect Dis. 2014;210:493-503 pubmed publisher

Huang C, Chen C, Liang Y, Hsu K. Long-term potentiation at excitatory synaptic inputs to the intercalated cell masses of the amygdala. Int J Neuropsychopharmacol. 2014;17:1233-42 pubmed publisher

Li H, Margolick J, Bream J, Nilles T, Langan S, Bui H, et al. Heterogeneity of CD4+ and CD8+ T-cell responses to cytomegalovirus in HIV-infected and HIV-uninfected men who have sex with men. J Infect Dis. 2014;210:400-4 pubmed publisher

Sauzullo I, Scrivo R, Mengoni F, Ermocida A, Coppola M, Valesini G, et al. Multi-functional flow cytometry analysis of CD4+ T cells as an immune biomarker for latent tuberculosis status in patients treated with tumour necrosis factor (TNF) antagonists. Clin Exp Immunol. 2014;176:410-7 pubmed publisher

De Filette M, Soehle S, Ulbert S, RICHNER J, Diamond M, Sinigaglia A, et al. Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge. PLoS ONE. 2014;9:e87837 pubmed publisher

Pineda M, Rodgers D, Al Riyami L, Harnett W, Harnett M. ES-62 protects against collagen-induced arthritis by resetting interleukin-22 toward resolution of inflammation in the joints. Arthritis Rheumatol. 2014;66:1492-503 pubmed publisher

Filbey K, Grainger J, Smith K, Boon L, Van Rooijen N, Harcus Y, et al. Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection. Immunol Cell Biol. 2014;92:436-48 pubmed publisher

Atik N, Kunii M, Avriyanti E, Furumoto N, Inami K, Yoshimura S, et al. The role of PKD in cell polarity, biosynthetic pathways, and organelle/F-actin distribution. Cell Struct Funct. 2014;39:61-77 pubmed

Tajiri K, Sakai S, Kimura T, Machino Ohtsuka T, Murakoshi N, Xu D, et al. Endothelin receptor antagonist exacerbates autoimmune myocarditis in mice. Life Sci. 2014;118:288-96 pubmed publisher

Dillon S, Lee E, Kotter C, Austin G, Dong Z, Hecht D, et al. An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia. Mucosal Immunol. 2014;7:983-94 pubmed publisher

Yao R, Lin Y, Li Q, Zhou X, Pan X, Bao Y, et al. Downregulation of T-bet/GATA-3 ratio induced by IL-11 treatment is responsible for Th1/Th2 balance restoration in human immune thrombocytopenic purpura (ITP). J Thromb Thrombolysis. 2014;38:183-9 pubmed publisher

Pieper J, Johansson S, Snir O, Linton L, Rieck M, Buckner J, et al. Peripheral and site-specific CD4(+) CD28(null) T cells from rheumatoid arthritis patients show distinct characteristics. Scand J Immunol. 2014;79:149-55 pubmed publisher

Kong H, Dong C, Xiong S. A novel vaccine p846 encoding Rv3615c, Mtb10.4, and Rv2660c elicits robust immune response and alleviates lung injury induced by Mycobacterium infection. Hum Vaccin Immunother. 2014;10:378-90 pubmed publisher

Chen W, Zhang Q, Kaplan B, Baker G, Kaminski N. Induced T cell cytokine production is enhanced by engineered nanoparticles. Nanotoxicology. 2014;8 Suppl 1:11-23 pubmed publisher

Reiling J, Olive A, Sanyal S, Carette J, Brummelkamp T, Ploegh H, et al. A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens. Nat Cell Biol. 2013;15:1473-85 pubmed publisher

Ohsaki Y, Cheng J, Yamairi K, Pan X, Hussain M, Fujimoto T. Inhibition of ADP-ribosylation suppresses aberrant accumulation of lipidated apolipoprotein B in the endoplasmic reticulum. FEBS Lett. 2013;587:3696-702 pubmed publisher

Jang H, Lim K, Lee S, Park B. Effects of n-3 PUFA on the CD4? type 2 helper T-cell-mediated immune responses in Fat-1 mice. Mol Nutr Food Res. 2014;58:365-75 pubmed publisher

Caster A, Kahn R. Recruitment of the Mint3 adaptor is necessary for export of the amyloid precursor protein (APP) from the Golgi complex. J Biol Chem. 2013;288:28567-80 pubmed publisher

Pinheiro A, Paramos de Carvalho D, Certal M, Costa M, Costa C, Magalhães Cardoso M, et al. Histamine induces ATP release from human subcutaneous fibroblasts, via pannexin-1 hemichannels, leading to Ca2+ mobilization and cell proliferation. J Biol Chem. 2013;288:27571-83 pubmed publisher

Saito S, Harada Y, Morodomi Y, Onimaru M, Yoshida K, Kyuragi R, et al. Ex vivo generation of highly purified and activated natural killer cells from human peripheral blood. Hum Gene Ther Methods. 2013;24:241-52 pubmed publisher

Chang D, Song S, You S, Lee J, Kim J, Racanelli V, et al. Programmed death-1 (PD-1)-dependent functional impairment of CD4(+) T cells in recurrent genital papilloma. Clin Exp Med. 2014;14:305-13 pubmed publisher

Colanzi A, Grimaldi G, Catara G, Valente C, Cericola C, Liberali P, et al. Molecular mechanism and functional role of brefeldin A-mediated ADP-ribosylation of CtBP1/BARS. Proc Natl Acad Sci U S A. 2013;110:9794-9 pubmed publisher

Nam S, Oh I, Yoon Y, Kwon B, Kang W, Kim H, et al. Apocynin regulates cytokine production of CD8(+) T cells. Clin Exp Med. 2014;14:261-8 pubmed publisher

Sana G, Lombard C, Vosters O, Jazouli N, Andre F, Stephenne X, et al. Adult human hepatocytes promote CD4(+) T-cell hyporesponsiveness via interleukin-10-producing allogeneic dendritic cells. Cell Transplant. 2014;23:1127-42 pubmed publisher

Robins G, Maclennan K, Boot Handford R, Sandle G. Rapid stimulation of human renal ENaC by cAMP in Xenopus laevis oocytes. J Physiol Biochem. 2013;69:419-27 pubmed publisher

Chatterjee S, Dwivedi V, Singh Y, Siddiqui I, Sharma P, Van Kaer L, et al. Early secreted antigen ESAT-6 of Mycobacterium tuberculosis promotes protective T helper 17 cell responses in a toll-like receptor-2-dependent manner. PLoS Pathog. 2011;7:e1002378 pubmed publisher

Fischer M, Davies M, Reider I, Heipertz E, Epler M, Sei J, et al. CD11b?, Ly6G? cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection. PLoS Pathog. 2011;7:e1002374 pubmed publisher

Haberthur K, Engelmann F, Park B, Barron A, Legasse A, Dewane J, et al. CD4 T cell immunity is critical for the control of simian varicella virus infection in a nonhuman primate model of VZV infection. PLoS Pathog. 2011;7:e1002367 pubmed publisher

Glennie S, Sepako E, Mzinza D, Harawa V, Miles D, Jambo K, et al. Impaired CD4 T cell memory response to Streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults. PLoS ONE. 2011;6:e25610 pubmed publisher

Peng R, Huang Z, Zhang Y, Yuan Z, Xia Y, Jiang W, et al. Circulating and tumor-infiltrating Foxp3⁺ regulatory T cell subset in Chinese patients with extranodal NK/T cell lymphoma. Int J Biol Sci. 2011;7:1027-36 pubmed

Martel C, Agger E, Poulsen J, Hammer Jensen T, Andresen L, Christensen D, et al. CAF01 potentiates immune responses and efficacy of an inactivated influenza vaccine in ferrets. PLoS ONE. 2011;6:e22891 pubmed publisher

Duncan C, Sheehy S, Ewer K, Douglas A, Collins K, Halstead F, et al. Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909. PLoS ONE. 2011;6:e22271 pubmed publisher

Lakhashe S, Wang W, Siddappa N, Hemashettar G, Polacino P, Hu S, et al. Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection. PLoS ONE. 2011;6:e22010 pubmed publisher

Appel H, Maier R, Wu P, Scheer R, Hempfing A, Kayser R, et al. Analysis of IL-17(+) cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response. Arthritis Res Ther. 2011;13:R95 pubmed publisher

Simmons R, Sharp C, Sims S, Kloverpris H, Goulder P, Simmonds P, et al. High frequency, sustained T cell responses to PARV4 suggest viral persistence in vivo. J Infect Dis. 2011;203:1378-87 pubmed publisher

Campbell J, Burdo T, Autissier P, Bombardier J, Westmoreland S, Soulas C, et al. Minocycline inhibition of monocyte activation correlates with neuronal protection in SIV neuroAIDS. PLoS ONE. 2011;6:e18688 pubmed publisher

Ferrari G, Korber B, Goonetilleke N, Liu M, Turnbull E, Salazar Gonzalez J, et al. Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection. PLoS Pathog. 2011;7:e1001273 pubmed publisher

Fang M, Roscoe F, Sigal L. Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and trafficking. J Exp Med. 2010;207:2369-81 pubmed publisher

Guizzunti G, Brady T, Fischer D, Malhotra V, Theodorakis E. Chemical biology studies on norrisolide. Bioorg Med Chem. 2010;18:2115-2122 pubmed publisher

Kim T, Billard M, Wieder E, McIntyre B, Komanduri K. Co-engagement of alpha(4)beta(1) integrin (VLA-4) and CD4 or CD8 is necessary to induce maximal Erk1/2 phosphorylation and cytokine production in human T cells. Hum Immunol. 2010;71:23-8 pubmed publisher

Gallorini S, Berti F, Mancuso G, Cozzi R, Tortoli M, Volpini G, et al. Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides. Proc Natl Acad Sci U S A. 2009;106:17481-6 pubmed publisher

Wang B, Kuroiwa J, He L, Charalambous A, Keler T, Steinman R. The human cancer antigen mesothelin is more efficiently presented to the mouse immune system when targeted to the DEC-205/CD205 receptor on dendritic cells. Ann N Y Acad Sci. 2009;1174:6-17 pubmed publisher

Yuan J, Johnson R, Huang R, Wichterman J, Jiang H, Hayton K, et al. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat Chem Biol. 2009;5:765-71 pubmed publisher

Huang X, Fan Z, Borowski L, Rinaldo C. Multiple T-cell responses to human immunodeficiency virus type 1 are enhanced by dendritic cells. Clin Vaccine Immunol. 2009;16:1504-16 pubmed publisher

Bruns L, Frey O, Morawietz L, Landgraf C, Volkmer R, Kamradt T. Immunization with an immunodominant self-peptide derived from glucose-6-phosphate isomerase induces arthritis in DBA/1 mice. Arthritis Res Ther. 2009;11:R117 pubmed publisher

Szaba F, Kummer L, Wilhelm L, Lin J, Parent M, Montminy Paquette S, et al. D27-pLpxL, an avirulent strain of Yersinia pestis, primes T cells that protect against pneumonic plague. Infect Immun. 2009;77:4295-304 pubmed publisher

Poehlmann H, Schefold J, Zuckermann Becker H, Volk H, Meisel C. Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis. Crit Care. 2009;13:R119 pubmed publisher

Rasche S, Busick R, Quinn A. GAD65-Specific Cytotoxic T Lymphocytes Mediate Beta-Cell Death and Loss of Function. Rev Diabet Stud. 2009;6:43-53 pubmed publisher

Gallez Hawkins G, Thao L, Palmer J, Dagis A, Li X, Franck A, et al. Increased programmed death-1 molecule expression in cytomegalovirus disease and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2009;15:872-80 pubmed publisher

Jordan K, Wilson E, Tait E, Fox B, Roos D, Bzik D, et al. Kinetics and phenotype of vaccine-induced CD8+ T-cell responses to Toxoplasma gondii. Infect Immun. 2009;77:3894-901 pubmed publisher

Boppana V, Thangamani S, Adler A, Wikel S. SAAG-4 is a novel mosquito salivary protein that programmes host CD4 T cells to express IL-4. Parasite Immunol. 2009;31:287-95 pubmed publisher

Chiacchio T, Casetti R, Butera O, Vanini V, Carrara S, Girardi E, et al. Characterization of regulatory T cells identified as CD4(+)CD25(high)CD39(+) in patients with active tuberculosis. Clin Exp Immunol. 2009;156:463-70 pubmed publisher

Häringer B, Lozza L, Steckel B, Geginat J. Identification and characterization of IL-10/IFN-gamma-producing effector-like T cells with regulatory function in human blood. J Exp Med. 2009;206:1009-17 pubmed publisher

Lay M, Callejo B, Chang S, Hong D, Lewis D, Carroll T, et al. Cationic lipid/DNA complexes (JVRS-100) combined with influenza vaccine (Fluzone) increases antibody response, cellular immunity, and antigenically drifted protection. Vaccine. 2009;27:3811-20 pubmed publisher

Colleton B, Huang X, Melhem N, Fan Z, Borowski L, Rappocciolo G, et al. Primary human immunodeficiency virus type 1-specific CD8+ T-cell responses induced by myeloid dendritic cells. J Virol. 2009;83:6288-99 pubmed publisher

Nair M, Du Y, Perrigoue J, Zaph C, Taylor J, Goldschmidt M, et al. Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung. J Exp Med. 2009;206:937-52 pubmed publisher

Gasser O, Bihl F, Sanghavi S, Rinaldo C, Rowe D, Hess C, et al. Treatment-dependent loss of polyfunctional CD8+ T-cell responses in HIV-infected kidney transplant recipients is associated with herpesvirus reactivation. Am J Transplant. 2009;9:794-803 pubmed publisher

Yamamoto T, Iwamoto N, Yamamoto H, Tsukamoto T, Kuwano T, Takeda A, et al. Polyfunctional CD4+ T-cell induction in neutralizing antibody-triggered control of simian immunodeficiency virus infection. J Virol. 2009;83:5514-24 pubmed publisher

Choi B, Kropf P. Evaluation of T cell responses in healing and nonhealing leishmaniasis reveals differences in T helper cell polarization ex vivo and in vitro. Parasite Immunol. 2009;31:199-209 pubmed publisher

Gangalum R, Bhat S. AlphaB-crystallin: a Golgi-associated membrane protein in the developing ocular lens. Invest Ophthalmol Vis Sci. 2009;50:3283-90 pubmed publisher

Zaia J, Sun J, Gallez Hawkins G, Thao L, Oki A, Lacey S, et al. The effect of single and combined activating killer immunoglobulin-like receptor genotypes on cytomegalovirus infection and immunity after hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2009;15:315-25 pubmed publisher

Saenz J, Sun W, Chang J, Li J, Bursulaya B, Gray N, et al. Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nat Chem Biol. 2009;5:157-65 pubmed publisher

Kong W, Wu L, Wallstrom T, Fischer W, Yang Z, Ko S, et al. Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination. J Virol. 2009;83:2201-15 pubmed publisher

Gredmark Russ S, Cheung E, Isaacson M, Ploegh H, Grotenbreg G. The CD8 T-cell response against murine gammaherpesvirus 68 is directed toward a broad repertoire of epitopes from both early and late antigens. J Virol. 2008;82:12205-12 pubmed publisher

Schubert S, Rogers P, Morschhäuser J. Gain-of-function mutations in the transcription factor MRR1 are responsible for overexpression of the MDR1 efflux pump in fluconazole-resistant Candida dubliniensis strains. Antimicrob Agents Chemother. 2008;52:4274-80 pubmed publisher

Doebis C, Siegmund K, Loddenkemper C, Lowe J, Issekutz A, Hamann A, et al. Cellular players and role of selectin ligands in leukocyte recruitment in a T-cell-initiated delayed-type hypersensitivity reaction. Am J Pathol. 2008;173:1067-76 pubmed publisher

Kolb G, Kristie T. Association of the cellular coactivator HCF-1 with the Golgi apparatus in sensory neurons. J Virol. 2008;82:9555-63 pubmed publisher

Cosmi L, De Palma R, Santarlasci V, Maggi L, Capone M, Frosali F, et al. Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. J Exp Med. 2008;205:1903-16 pubmed publisher

Monahan B, Villen J, Marguerat S, Bahler J, Gygi S, Winston F. Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast. Nat Struct Mol Biol. 2008;15:873-80 pubmed publisher

Johnston A, Arnadottir S, Gudjonsson J, Aphale A, Sigmarsdottir A, Gunnarsson S, et al. Obesity in psoriasis: leptin and resistin as mediators of cutaneous inflammation. Br J Dermatol. 2008;159:342-50 pubmed publisher

Lochner M, Peduto L, Cherrier M, Sawa S, Langa F, Varona R, et al. In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells. J Exp Med. 2008;205:1381-93 pubmed publisher

Tewalt E, Maynard J, Walters J, Schell A, Berwin B, Nicchitta C, et al. Redundancy renders the glycoprotein 96 receptor scavenger receptor A dispensable for cross priming in vivo. Immunology. 2008;125:480-91 pubmed publisher

Zhou L, Lopes J, Chong M, Ivanov I, Min R, Victora G, et al. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature. 2008;453:236-40 pubmed publisher

Pettit G, Hogan F, Xu J, Tan R, Nogawa T, Cichacz Z, et al. Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms(1a,). J Nat Prod. 2008;71:438-44 pubmed publisher

Popmihajlov Z, Smith K. Negative feedback regulation of T cells via interleukin-2 and FOXP3 reciprocity. PLoS ONE. 2008;3:e1581 pubmed publisher

Speiser D, Baumgaertner P, Voelter V, Devevre E, Barbey C, Rufer N, et al. Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen. Proc Natl Acad Sci U S A. 2008;105:3849-54 pubmed publisher

Williams C, Harry R, McLeod J. Apoptotic cells induce dendritic cell-mediated suppression via interferon-gamma-induced IDO. Immunology. 2008;124:89-101 pubmed

Alvarez R, Reading J, King D, Hayes M, Easterbrook P, Farzaneh F, et al. WFDC1/ps20 is a novel innate immunomodulatory signature protein of human immunodeficiency virus (HIV)-permissive CD4+ CD45RO+ memory T cells that promotes infection by upregulating CD54 integrin expression and is elevated in HIV type 1 infection. J Virol. 2008;82:471-86 pubmed

Viaud J, Zeghouf M, Barelli H, Zeeh J, Padilla A, Guibert B, et al. Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes. Proc Natl Acad Sci U S A. 2007;104:10370-5 pubmed

Zhang Q, Major M, Takanashi S, Camp N, Nishiya N, Peters E, et al. Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Proc Natl Acad Sci U S A. 2007;104:7444-8 pubmed

Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed

Cheng S, Clancy C, Nguyen K, Clapp W, Nguyen M. A Candida albicans petite mutant strain with uncoupled oxidative phosphorylation overexpresses MDR1 and has diminished susceptibility to fluconazole and voriconazole. Antimicrob Agents Chemother. 2007;51:1855-8 pubmed

Amagata T, Morinaka B, Amagata A, Tenney K, Valeriote F, Lobkovsky E, et al. A chemical study of cyclic depsipeptides produced by a sponge-derived fungus. J Nat Prod. 2006;69:1560-5 pubmed

Anadu N, Davisson V, Cushman M. Synthesis and anticancer activity of brefeldin A ester derivatives. J Med Chem. 2006;49:3897-905 pubmed

MacDonald M, Lamerdin J, Owens S, Keon B, Bilter G, Shang Z, et al. Identifying off-target effects and hidden phenotypes of drugs in human cells. Nat Chem Biol. 2006;2:329-37 pubmed

Zeghouf M, Guibert B, Zeeh J, Cherfils J. Arf, Sec7 and Brefeldin A: a model towards the therapeutic inhibition of guanine nucleotide-exchange factors. Biochem Soc Trans. 2005;33:1265-8 pubmed

Nebenführ A, Ritzenthaler C, Robinson D. Brefeldin A: deciphering an enigmatic inhibitor of secretion. Plant Physiol. 2002;130:1102-8 pubmed

Jackson C. Brefeldin A revealing the fundamental principles governing membrane dynamics and protein transport. Subcell Biochem. 2000;34:233-72 pubmed

Chardin P, McCormick F. Brefeldin A: the advantage of being uncompetitive. Cell. 1999;97:153-5 pubmed

Satiat Jeunemaitre B, Cole L, Bourett T, Howard R, Hawes C. Brefeldin A effects in plant and fungal cells: something new about vesicle trafficking?. J Microsc. 1996;181:162-77 pubmed

Misumi Y, Miki K, Takatsuki A, Tamura G, Ikehara Y. Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes. J Biol Chem. 1986;261:11398-403 pubmed

Pelham H. Multiple targets for brefeldin A. Cell. 1991;67:449-51 pubmed

Klausner R, Donaldson J, Lippincott Schwartz J. Brefeldin A: insights into the control of membrane traffic and organelle structure. J Cell Biol. 1992;116:1071-80 pubmed

Hunziker W, Whitney J, Mellman I. Brefeldin A and the endocytic pathway. Possible implications for membrane traffic and sorting. FEBS Lett. 1992;307:93-6 pubmed

Betina V. Biological effects of the antibiotic brefeldin A (decumbin, cyanein, ascotoxin, synergisidin): a retrospective. Folia Microbiol (Praha). 1992;37:3-11 pubmed