This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
2′(3′)-O-(4-Benzoylbenzoyl)adenosine 5′-triphosphate triethylammonium salt
catalog :
B6396
citations: 34
Reference
Jeong J, Kim J, Hong H, Wangemann P, Marcus D, Jung J, et al. P2RX2 and P2RX4 receptors mediate cation absorption in transitional cells and supporting cells of the utricular macula. Hear Res. 2020;386:107860 pubmed publisher
Tozzi M, Hansen J, Novak I. Pannexin-1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration. Acta Physiol (Oxf). 2020;228:e13360 pubmed publisher
Wang J, Pendurthi U, Rao L. Acid sphingomyelinase plays a critical role in LPS- and cytokine-induced tissue factor procoagulant activity. Blood. 2019;134:645-655 pubmed publisher
Martínez Frailes C, di Lauro C, Bianchi C, de Diego García L, Sebastián Serrano A, Bosca L, et al. Amyloid Peptide Induced Neuroinflammation Increases the P2X7 Receptor Expression in Microglial Cells, Impacting on Its Functionality. Front Cell Neurosci. 2019;13:143 pubmed publisher
Schuchardt M, Prüfer N, Tu Y, Herrmann J, Hu X, Chebli S, et al. Dysfunctional high-density lipoprotein activates toll-like receptors via serum amyloid A in vascular smooth muscle cells. Sci Rep. 2019;9:3421 pubmed publisher
Wang L, Schmidt S, Larsen P, Meyer J, Roush W, Latz E, et al. Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells. J Mol Med (Berl). 2019;97:523-532 pubmed publisher
Lee S, Roh S, Lee J, Sung N, Liu J, Tsai F. Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation. Cell Rep. 2019;26:29-36.e3 pubmed publisher
Martin E, Amar M, Dalle C, Youssef I, Boucher C, Le Duigou C, et al. New role of P2X7 receptor in an Alzheimer's disease mouse model. Mol Psychiatry. 2019;24:108-125 pubmed publisher
D Addio F, Vergani A, Potena L, Maestroni A, Usuelli V, Ben Nasr M, et al. P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes. J Clin Invest. 2018;128:3490-3503 pubmed publisher
Tanigawa H, Toyoda F, Kumagai K, Okumura N, Maeda T, Matsuura H, et al. P2X7 ionotropic receptor is functionally expressed in rabbit articular chondrocytes and mediates extracellular ATP cytotoxicity. Purinergic Signal. 2018;14:245-258 pubmed publisher
Peña Altamira L, Polazzi E, Giuliani P, Beraudi A, Massenzio F, Mengoni I, et al. Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors. Neurochem Int. 2018;115:37-49 pubmed publisher
Beneventano M, Spampinato S, Merlo S, Chisari M, Platania P, Ragusa M, et al. Shedding of Microvesicles from Microglia Contributes to the Effects Induced by Metabotropic Glutamate Receptor 5 Activation on Neuronal Death. Front Pharmacol. 2017;8:812 pubmed publisher
Zheng H, Högberg J, Stenius U. ATM-activated autotaxin (ATX) propagates inflammation and DNA damage in lung epithelial cells: a new mode of action for silica-induced DNA damage?. Carcinogenesis. 2017;38:1196-1206 pubmed publisher
Kupenova P, Popova E, Vitanova L. Purinergic modulation of frog electroretinographic responses: The role of the ionotropic receptor P2X7. Vis Neurosci. 2017;34:E015 pubmed publisher
Robles Martínez L, Garay E, Martel Gallegos M, Cisneros Mejorado A, Perez Montiel D, Lara A, et al. Kca3.1 Activation Via P2y2 Purinergic Receptors Promotes Human Ovarian Cancer Cell (Skov-3) Migration. Sci Rep. 2017;7:4340 pubmed publisher
Backhaus S, Zakrzewicz A, Richter K, Damm J, Wilker S, Fuchs Moll G, et al. Surfactant inhibits ATP-induced release of interleukin-1β via nicotinic acetylcholine receptors. J Lipid Res. 2017;58:1055-1066 pubmed publisher
Portillo J, Lopez Corcino Y, Dubyak G, Kern T, Matsuyama S, Subauste C. Ligation of CD40 in Human Müller Cells Induces P2X7 Receptor-Dependent Death of Retinal Endothelial Cells. Invest Ophthalmol Vis Sci. 2016;57:6278-6286 pubmed publisher
Engel T, Brennan G, Sanz Rodriguez A, Alves M, Beamer E, Watters O, et al. A calcium-sensitive feed-forward loop regulating the expression of the ATP-gated purinergic P2X7 receptor via specificity protein 1 and microRNA-22. Biochim Biophys Acta Mol Cell Res. 2017;1864:255-266 pubmed publisher
Bhattacharya S, Imbery J, Ampem P, Giovannucci D. Crosstalk between purinergic receptors and canonical signaling pathways in the mouse salivary gland. Cell Calcium. 2015;58:589-97 pubmed publisher
Csóka B, Németh Z, Törő G, Idzko M, Zech A, Koscsó B, et al. Extracellular ATP protects against sepsis through macrophage P2X7 purinergic receptors by enhancing intracellular bacterial killing. FASEB J. 2015;29:3626-37 pubmed publisher
Xiao Z, Li Y, Sun M. Activation of P2X7 receptors in the midbrain periaqueductal gray of rats facilitates morphine tolerance. Pharmacol Biochem Behav. 2015;135:145-53 pubmed publisher
D Alimonte I, Nargi E, Zuccarini M, Lanuti P, Di Iorio P, Giuliani P, et al. Potentiation of temozolomide antitumor effect by purine receptor ligands able to restrain the in vitro growth of human glioblastoma stem cells. Purinergic Signal. 2015;11:331-46 pubmed publisher
Young C, Sinadinos A, Lefebvre A, Chan P, Arkle S, Vaudry D, et al. A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90. Autophagy. 2015;11:113-30 pubmed publisher
Choi I, Cho J, Lee M, Jang I. Enzymatic conversion of ATP to adenosine contributes to ATP-induced inhibition of glutamate release in rat medullary dorsal horn neurons. Neuropharmacology. 2015;93:94-102 pubmed publisher
Huang Y, Yen J, Lee J, Liao J, Liaw W, Huang C. P2X7 is involved in the anti-inflammation effects of levobupivacaine. J Surg Res. 2015;193:407-14 pubmed publisher
Ottow M, Klaver E, van der Pouw Kraan T, Heijnen P, Laan L, Kringel H, et al. The helminth Trichuris suis suppresses TLR4-induced inflammatory responses in human macrophages. Genes Immun. 2014;15:477-86 pubmed publisher
Rubini P, Pagel G, Mehri S, Marquardt P, Riedel T, Illes P. Functional P2X7 receptors at cultured hippocampal astrocytes but not neurons. Naunyn Schmiedebergs Arch Pharmacol. 2014;387:943-54 pubmed publisher
Codocedo J, Godoy J, Poblete M, Inestrosa N, Huidobro Toro J. ATP induces NO production in hippocampal neurons by P2X(7) receptor activation independent of glutamate signaling. PLoS ONE. 2013;8:e57626 pubmed publisher
Soltoff S, Hedden L. Isoproterenol and cAMP block ERK phosphorylation and enhance [Ca2+]i increases and oxygen consumption by muscarinic receptor stimulation in rat parotid and submandibular acinar cells. J Biol Chem. 2010;285:13337-48 pubmed publisher
Bavan S, Straub V, Blaxter M, Ennion S. A P2X receptor from the tardigrade species Hypsibius dujardini with fast kinetics and sensitivity to zinc and copper. BMC Evol Biol. 2009;9:17 pubmed publisher
Zhao J, Li L, Leissring M. Insulin-degrading enzyme is exported via an unconventional protein secretion pathway. Mol Neurodegener. 2009;4:4 pubmed publisher
Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, Onoue M, et al. ATP drives lamina propria T(H)17 cell differentiation. Nature. 2008;455:808-12 pubmed publisher
Stefano L, Rössler O, Griesemer D, Hoth M, Thiel G. P2X(7) receptor stimulation upregulates Egr-1 biosynthesis involving a cytosolic Ca(2+) rise, transactivation of the EGF receptor and phosphorylation of ERK and Elk-1. J Cell Physiol. 2007;213:36-44 pubmed
Svensson C, Zattoni M, Serhan C. Lipoxins and aspirin-triggered lipoxin inhibit inflammatory pain processing. J Exp Med. 2007;204:245-52 pubmed
product information
Catalog Number :
B6396
Product Name :
2′(3′)-O-(4-Benzoylbenzoyl)adenosine 5′-triphosphate triethylammonium salt
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥93%
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA