This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Brain-derived neurotrophic factor human
catalog :
B3795
citations: 50
Reference
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Fukusumi Y, Meier F, Götz S, Matheus F, Irmler M, Beckervordersandforth R, et al. Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse. J Neurosci. 2015;35:13385-401 pubmed publisher
Paczkowska E, Łuczkowska K, Piecyk K, Rogińska D, Pius Sadowska E, Ustianowski P, et al. The influence of BDNF on human umbilical cord blood stem/progenitor cells: implications for stem cell-based therapy of neurodegenerative disorders. Acta Neurobiol Exp (Wars). 2015;75:172-91 pubmed
Lee K, Prescott S. Chloride dysregulation and inhibitory receptor blockade yield equivalent disinhibition of spinal neurons yet are differentially reversed by carbonic anhydrase blockade. Pain. 2015;156:2431-7 pubmed publisher
Noren Hooten N, Ejiogu N, Zonderman A, Evans M. Protective Effects of BDNF against C-Reactive Protein-Induced Inflammation in Women. Mediators Inflamm. 2015;2015:516783 pubmed publisher
Zhang J, Götz S, Vogt Weisenhorn D, Simeone A, Wurst W, Prakash N. A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1(+/-) mice. Neurobiol Dis. 2015;82:32-45 pubmed publisher
Calvo L, Anta B, López Benito S, Martín Rodriguez C, Lee F, Pérez P, et al. Bex3 Dimerization Regulates NGF-Dependent Neuronal Survival and Differentiation by Enhancing trkA Gene Transcription. J Neurosci. 2015;35:7190-202 pubmed publisher
Leitmeyer K, Glutz A, Radojevic V, Setz C, Huerzeler N, Bumann H, et al. Inhibition of mTOR by Rapamycin Results in Auditory Hair Cell Damage and Decreased Spiral Ganglion Neuron Outgrowth and Neurite Formation In Vitro. Biomed Res Int. 2015;2015:925890 pubmed publisher
Watters A, Rom S, Hill J, Dematatis M, Zhou Y, Merkel S, et al. Identification and dynamic regulation of tight junction protein expression in human neural stem cells. Stem Cells Dev. 2015;24:1377-89 pubmed publisher
Cosset Ã, Martinez Y, Preynat Seauve O, Lobrinus J, Tapparel C, Cordey S, et al. Human three-dimensional engineered neural tissue reveals cellular and molecular events following cytomegalovirus infection. Biomaterials. 2015;53:296-308 pubmed publisher
Borkowska P, Kowalska J, Fila Danilow A, Bielecka A, Paul Samojedny M, Kowalczyk M, et al. Affect of antidepressants on the in vitro differentiation of rat bone marrow mesenchymal stem cells into neuronal cells. Eur J Pharm Sci. 2015;73:81-7 pubmed publisher
Low W, Rujitanaroj P, Wang F, Wang J, Chew S. Nanofiber-mediated release of retinoic acid and brain-derived neurotrophic factor for enhanced neuronal differentiation of neural progenitor cells. Drug Deliv Transl Res. 2015;5:89-100 pubmed publisher
Li Y, Polak U, Bhalla A, Rozwadowska N, Butler J, Lynch D, et al. Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia. Mol Ther. 2015;23:1055-1065 pubmed publisher
Yamagishi R, Aihara M. Neuroprotective effect of astaxanthin against rat retinal ganglion cell death under various stresses that induce apoptosis and necrosis. Mol Vis. 2014;20:1796-805 pubmed
Zhu G, Li J, He L, Wang X, Hong X. MPTP-induced changes in hippocampal synaptic plasticity and memory are prevented by memantine through the BDNF-TrkB pathway. Br J Pharmacol. 2015;172:2354-68 pubmed publisher
Lamas N, Johnson Kerner B, Roybon L, Kim Y, Garcia Diaz A, Wichterle H, et al. Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures. PLoS ONE. 2014;9:e110324 pubmed publisher
Steward O, Sharp K, Yee K, Hatch M, Bonner J. Characterization of ectopic colonies that form in widespread areas of the nervous system with neural stem cell transplants into the site of a severe spinal cord injury. J Neurosci. 2014;34:14013-21 pubmed publisher
Riffault B, Medina I, Dumon C, Thalman C, Ferrand N, Friedel P, et al. Pro-brain-derived neurotrophic factor inhibits GABAergic neurotransmission by activating endocytosis and repression of GABAA receptors. J Neurosci. 2014;34:13516-34 pubmed publisher
Zhang H, Song N, Jiang H, Bi M, Xie J. Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor inhibit ferrous iron influx via divalent metal transporter 1 and iron regulatory protein 1 regulation in ventral mesencephalic neurons. Biochim Biophys Acta. 2014;1843:2967-75 pubmed publisher
Chen F, Yu Y, Wang P, Dong Y, Wang T, Zuo X, et al. Brain-derived neurotrophic factor accelerates gut motility in slow-transit constipation. Acta Physiol (Oxf). 2014;212:226-38 pubmed publisher
Lin C, Hung S, Chen H, Tsou H, Fong Y, Wang S, et al. Brain-derived neurotrophic factor increases vascular endothelial growth factor expression and enhances angiogenesis in human chondrosarcoma cells. Biochem Pharmacol. 2014;91:522-33 pubmed publisher
Czarnecka M, Trinh E, Lu C, Kuan Celarier A, Galli S, Hong S, et al. Neuropeptide Y receptor Y5 as an inducible pro-survival factor in neuroblastoma: implications for tumor chemoresistance. Oncogene. 2015;34:3131-43 pubmed publisher
Alvarez A, Aleixandre M, Linares C, Masliah E, Moessler H. Apathy and APOE4 are associated with reduced BDNF levels in Alzheimer's disease. J Alzheimers Dis. 2014;42:1347-55 pubmed publisher
Sung M, Wei E, Chavez E, Jain N, Levano S, Binkert L, et al. Inhibition of MMP-2 but not MMP-9 influences inner ear spiral ganglion neurons in vitro. Cell Mol Neurobiol. 2014;34:1011-21 pubmed publisher
Vargas Perez H, Bahi A, Bufalino M, Ting A Kee R, Maal Bared G, Lam J, et al. BDNF signaling in the VTA links the drug-dependent state to drug withdrawal aversions. J Neurosci. 2014;34:7899-909 pubmed publisher
Xin J, Ma L, Zhang T, Yu H, Wang Y, Kong L, et al. Involvement of BDNF signaling transmission from basolateral amygdala to infralimbic prefrontal cortex in conditioned taste aversion extinction. J Neurosci. 2014;34:7302-13 pubmed publisher
Chen Q, Zhang X, Zhao Y, Zhou X, Sun L, Zeng S, et al. Sexual differences in cell proliferation in the ventricular zone, cell migration and differentiation in the HVC of juvenile Bengalese finch. PLoS ONE. 2014;9:e97403 pubmed publisher
Aihara M, Chen Y, Uchida S, Nakayama M, Araie M. Hyperbaric pressure and increased susceptibility to glutamate toxicity in retinal ganglion cells in vitro. Mol Vis. 2014;20:606-15 pubmed
Tanaka K, Okugawa Y, Toiyama Y, Inoue Y, Saigusa S, Kawamura M, et al. Brain-derived neurotrophic factor (BDNF)-induced tropomyosin-related kinase B (Trk B) signaling is a potential therapeutic target for peritoneal carcinomatosis arising from colorectal cancer. PLoS ONE. 2014;9:e96410 pubmed publisher
Kulikov A, Fursenko D, Khotskin N, Bazovkina D, Kulikov V, Naumenko V, et al. Spatial learning in the Morris water maze in mice genetically different in the predisposition to catalepsy: the effect of intraventricular treatment with brain-derived neurotrophic factor. Pharmacol Biochem Behav. 2014;122:266-72 pubmed publisher
Sharp K, Yee K, Steward O. A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury. Exp Neurol. 2014;257:186-204 pubmed publisher
Naumenko V, Kondaurova E, Bazovkina D, Tsybko A, Il chibaeva T, Popova N. On the role of 5-HT(1A) receptor gene in behavioral effect of brain-derived neurotrophic factor. J Neurosci Res. 2014;92:1035-43 pubmed publisher
Liu G, Anisman H, Bobyn J, Hayley S. Interaction between nonviral reprogrammed fibroblast stem cells and trophic factors for brain repair. Mol Neurobiol. 2014;50:673-84 pubmed publisher
Rosas Vidal L, Do Monte F, Sotres Bayon F, Quirk G. Hippocampal--prefrontal BDNF and memory for fear extinction. Neuropsychopharmacology. 2014;39:2161-9 pubmed publisher
Oliver L, Hue E, Priault M, Vallette F. Basal autophagy decreased during the differentiation of human adult mesenchymal stem cells. Stem Cells Dev. 2012;21:2779-88 pubmed publisher
Oliver L, Hue E, Rossignol J, Bougras G, Hulin P, Naveilhan P, et al. Distinct roles of Bcl-2 and Bcl-Xl in the apoptosis of human bone marrow mesenchymal stem cells during differentiation. PLoS ONE. 2011;6:e19820 pubmed publisher
Kuczewski N, Porcher C, Gaiarsa J. Activity-dependent dendritic secretion of brain-derived neurotrophic factor modulates synaptic plasticity. Eur J Neurosci. 2010;32:1239-44 pubmed publisher
Sun W, Salvi R. Brain derived neurotrophic factor and neurotrophic factor 3 modulate neurotransmitter receptor expressions on developing spiral ganglion neurons. Neuroscience. 2009;164:1854-66 pubmed publisher
Hong S, Jang G, Oh H, Koo O, Park J, Park H, et al. The effects of brain-derived neurotrophic factor and metformin on in vitro developmental competence of bovine oocytes. Zygote. 2009;17:187-93 pubmed publisher
Tian B, Yang Q, Mao Z. Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death. Nat Cell Biol. 2009;11:211-8 pubmed publisher
Hermel E, Gafni J, Propp S, Leavitt B, Wellington C, Young J, et al. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease. Cell Death Differ. 2004;11:424-38 pubmed
Das K, Chao S, White L, Haines W, Harry G, Tilson H, et al. Differential patterns of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNA and protein levels in developing regions of rat brain. Neuroscience. 2001;103:739-61 pubmed
Benninger Y, Marino S, Hardegger R, Weissmann C, Aguzzi A, Brandner S. Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice. Brain Pathol. 2000;10:330-41 pubmed
product information
Catalog Number :
B3795
Product Name :
Brain-derived neurotrophic factor human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
BDNF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA