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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
BQ-788
catalog :
B157
citations: 25
Reference
Lekkas P, Kontonika M, Georgiou E, La Rocca V, Mouchtouri E, Mourouzis I, et al. Endothelin receptors in the brain modulate autonomic responses and arrhythmogenesis during acute myocardial infarction in rats. Life Sci. 2019;239:117062 pubmed publisher
Gomes L, Chichorro J, Araya E, de Oliveira J, Rae G. Facial hyperalgesia due to direct action of endothelin-1 in the trigeminal ganglion of mice. J Pharm Pharmacol. 2018;70:893-900 pubmed publisher
Kansanen E, Kuosmanen S, Ruotsalainen A, Hynynen H, Levonen A. Nitro-Oleic Acid Regulates Endothelin Signaling in Human Endothelial Cells. Mol Pharmacol. 2017;92:481-490 pubmed publisher
Tu N, Katano T, Matsumura S, Funatsu N, Pham V, Fujisawa J, et al. Na+ /K+ -ATPase coupled to endothelin receptor type B stimulates peripheral nerve regeneration via lactate signalling. Eur J Neurosci. 2017;46:2096-2107 pubmed publisher
Motherwell J, Azimi M, Spicer K, Alves N, Hodges N, Breslin J, et al. Evaluation of Arteriolar Smooth Muscle Cell Function in an Ex Vivo Microvascular Network Model. Sci Rep. 2017;7:2195 pubmed publisher
Bellien J, Iacob M, Monteil C, Rémy Jouet I, Roche C, Duflot T, et al. Physiological role of endothelin-1 in flow-mediated vasodilatation in humans and impact of cardiovascular risk factors. J Hypertens. 2017;35:1204-1212 pubmed publisher
Wenner M, Sebzda K, Kuczmarski A, Pohlig R, Edwards D. ETB receptor contribution to vascular dysfunction in postmenopausal women. Am J Physiol Regul Integr Comp Physiol. 2017;313:R51-R57 pubmed publisher
Vercauteren M, Trensz F, Pasquali A, Cattaneo C, Strasser D, Hess P, et al. Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention. J Pharmacol Exp Ther. 2017;361:322-333 pubmed publisher
Claudino R, Leite D, Bento A, Chichorro J, Calixto J, Rae G. Potential role for ET-2 acting through ETA receptors in experimental colitis in mice. Inflamm Res. 2017;66:141-155 pubmed publisher
Fellner R, Guan Z, Cook A, Pollock D, Inscho E. Endothelin contributes to blunted renal autoregulation observed with a high-salt diet. Am J Physiol Renal Physiol. 2015;309:F687-96 pubmed publisher
Durgan D, Crossland R, Lloyd E, Phillips S, Bryan R. Increased cerebrovascular sensitivity to endothelin-1 in a rat model of obstructive sleep apnea: a role for endothelin receptor B. J Cereb Blood Flow Metab. 2015;35:402-11 pubmed publisher
Tanaka A, Yuasa S, Mearini G, Egashira T, Seki T, Kodaira M, et al. Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes. J Am Heart Assoc. 2014;3:e001263 pubmed publisher
Patel C, Narayanan S, Zhang W, Xu Z, Sukumari Ramesh S, Dhandapani K, et al. Activation of the endothelin system mediates pathological angiogenesis during ischemic retinopathy. Am J Pathol. 2014;184:3040-51 pubmed publisher
Lachaud C, López Beas J, Soria B, Hmadcha A. EGF-induced adipose tissue mesothelial cells undergo functional vascular smooth muscle differentiation. Cell Death Dis. 2014;5:e1304 pubmed publisher
François A, Laziz I, Rimbaud S, Grebert D, Durieux D, Pajot Augy E, et al. Early survival factor deprivation in the olfactory epithelium enhances activity-driven survival. Front Cell Neurosci. 2013;7:271 pubmed publisher
Li J, Cao L, Xu C, Wang J, Cao Y. Minimally modified LDL upregulates endothelin type A receptors in rat coronary arterial smooth muscle cells. Mediators Inflamm. 2013;2013:656570 pubmed publisher
Wang Z, Li A, Guo Q, Zhang J, An Q, Guo Y, et al. Effects of cyclic intermittent hypoxia on ET-1 responsiveness and endothelial dysfunction of pulmonary arteries in rats. PLoS ONE. 2013;8:e58078 pubmed publisher
Lachaud C, Pezzolla D, Dominguez Rodriguez A, Smani T, Soria B, Hmadcha A. Functional vascular smooth muscle-like cells derived from adult mouse uterine mesothelial cells. PLoS ONE. 2013;8:e55181 pubmed publisher
Gatfield J, Mueller Grandjean C, Sasse T, Clozel M, Nayler O. Slow receptor dissociation kinetics differentiate macitentan from other endothelin receptor antagonists in pulmonary arterial smooth muscle cells. PLoS ONE. 2012;7:e47662 pubmed publisher
Baltatu O, Iliescu R, Zaugg C, Reckelhoff J, Louie P, Schumacher C, et al. Antidiuretic effects of the endothelin receptor antagonist avosentan. Front Physiol. 2012;3:103 pubmed publisher
Faisy C, Pinto F, Le Guen M, Naline E, Grassin Delyle S, Sage E, et al. Airway response to acute mechanical stress in a human bronchial model of stretch. Crit Care. 2011;15:R208 pubmed publisher
Stösser S, Agarwal N, Tappe Theodor A, Yanagisawa M, Kuner R. Dissecting the functional significance of endothelin A receptors in peripheral nociceptors in vivo via conditional gene deletion. Pain. 2010;148:206-14 pubmed publisher
Helbing T, Volkmar F, Goebel U, Heinke J, Diehl P, Pahl H, et al. Krüppel-like factor 15 regulates BMPER in endothelial cells. Cardiovasc Res. 2010;85:551-9 pubmed publisher
Ishikawa K, Ihara M, Noguchi K, Mase T, Mino N, Saeki T, et al. Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788. Proc Natl Acad Sci U S A. 1994;91:4892-6 pubmed
Karaki H, Sudjarwo S, Hori M. Novel antagonist of endothelin ETB1 and ETB2 receptors, BQ-788: effects on blood vessel and small intestine. Biochem Biophys Res Commun. 1994;205:168-73 pubmed
product information
Catalog Number :
B157
Product Name :
BQ-788
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥95%, solid
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA