This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
(S)-(−)-Bay K8644
catalog :
B133
citations: 31
Reference
Segovia M, Russo S, Jeldres M, Mahmoud Y, Perez V, Duhalde M, et al. Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation. Cancer Cell. 2019;35:767-781.e6 pubmed publisher
Singhal A, Jie L, Kumar P, Hong G, Leow M, Paleja B, et al. Metformin as adjunct antituberculosis therapy. Sci Transl Med. 2014;6:263ra159 pubmed publisher
Durmus N, Kaya T, Gulturk S, Demir T, Parlak M, Altun A. The effects of L type calcium channels on the electroencephalogram recordings in WAG/RIJ rat model of absence epilepsy. Eur Rev Med Pharmacol Sci. 2013;17:1149-54 pubmed
Zhang L, Ouyang M, Ganellin C, Thomas S. The slow afterhyperpolarization: a target of ?1-adrenergic signaling in hippocampus-dependent memory retrieval. J Neurosci. 2013;33:5006-16 pubmed publisher
Iakovenko I, Zhirnov V, Kozachenko O, Shablykin O, Brovarets V. [Participation of proteinkinase CK2 in regulation of human erythrocytes plasma membrane redox system activity: relative contribution of ca(2+)-dependent and ca(2+)-independent mechanisms of its activation]. Ukr Biokhim Zh (1999). 2012;84:55-61 pubmed
Viola H, Davies S, Filipovska A, Hool L. L-type Ca(2+) channel contributes to alterations in mitochondrial calcium handling in the mdx ventricular myocyte. Am J Physiol Heart Circ Physiol. 2013;304:H767-75 pubmed publisher
Benaim G, Garcia Marchan Y, Reyes C, Uzcanga G, Figarella K. Identification of a sphingosine-sensitive Ca2+ channel in the plasma membrane of Leishmania mexicana. Biochem Biophys Res Commun. 2013;430:1091-6 pubmed publisher
Brunet S, Scheuer T, Catterall W. Increased intracellular magnesium attenuates β-adrenergic stimulation of the cardiac Ca(V)1.2 channel. J Gen Physiol. 2013;141:85-94 pubmed publisher
Bernardes M, de Carvalho F, Lima Silveira L, de Paula J, Bara M, Garrote C, et al. Hypotensive effect of Aspidosperma subincanum Mart. in rats and its mechanism of vasorelaxation in isolated arteries. J Ethnopharmacol. 2013;145:227-32 pubmed publisher
Hu H, Li S, Wang P, Yan H, Cao X, Hou F, et al. An L-type calcium channel agonist, bay K8644, extends the window of intervention against ischemic neuronal injury. Mol Neurobiol. 2013;47:280-9 pubmed publisher
Hernandez J, Janssen L. L-type Ca(2+) channels, Ca(2+)-induced Ca(2+) release, and BK(Ca) channels in airway stretch-induced contraction. Eur J Pharmacol. 2012;696:161-5 pubmed publisher
Hibberd T, Zagorodnyuk V, Spencer N, Brookes S. Identification and mechanosensitivity of viscerofugal neurons. Neuroscience. 2012;225:118-29 pubmed publisher
Zhang L, Zhang S, Cao Y. Vasodilation and hypotension of CZ454, an analogue of lacidipine through inhibiting extracellular calcium influx. Arzneimittelforschung. 2012;62:439-45 pubmed publisher
Chang M, Chang C, de Lange E, Xu L, O ROURKE B, Karagueuzian H, et al. Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers. Biophys J. 2012;102:2706-14 pubmed publisher
Saika E, Miyamoto Y, Hibi Y, Muramatsu S, Nabeshima T, Nitta A. [JSNP Excellent Presentation Award for AsCNP 2011: role of a novel molecule "shati" in animal model of dystonia]. Nihon Shinkei Seishin Yakurigaku Zasshi. 2012;32:121-2 pubmed
Yamamura H, Ohya S, Muraki K, Imaizumi Y. Involvement of inositol 1,4,5-trisphosphate formation in the voltage-dependent regulation of the Ca(2+) concentration in porcine coronary arterial smooth muscle cells. J Pharmacol Exp Ther. 2012;342:486-96 pubmed publisher
Hopps J, Dunn W, Randall M. Vasorelaxation to capsaicin and its effects on calcium influx in arteries. Eur J Pharmacol. 2012;681:88-93 pubmed
Lawton B, Brown N, Reilly C, Brookes Z. Role of L-type calcium channels in altered microvascular responses to propofol in hypertension. Br J Anaesth. 2012;108:929-35 pubmed publisher
Grzesk G, Wiciński M, Malinowski B, Grześk E, Manysiak S, Odrowaz Sypniewska G, et al. Calcium blockers inhibit cyclosporine A-induced hyperreactivity of vascular smooth muscle cells. Mol Med Rep. 2012;5:1469-74 pubmed publisher
Jantschak F, Pertz H. Alpha2C-adrenoceptors play a prominent role in sympathetic constriction of porcine pulmonary arteries. Naunyn Schmiedebergs Arch Pharmacol. 2012;385:595-603 pubmed publisher
Jonsson M, Vos M, Mirams G, Duker G, Sartipy P, De Boer T, et al. Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG. J Mol Cell Cardiol. 2012;52:998-1008 pubmed publisher
Xu M, Wu Y, Liu S, Li Q, He R. Electrophysiological effects of hydrogen sulfide on human atrial fibers. Chin Med J (Engl). 2011;124:3455-9 pubmed
Lu N, Cheng L, Zhang Y, Lü B, Li Y, Zhao Z. Involvement of ryanodine receptors in tetanic sciatic stimulation-induced long-term potentiation of spinal dorsal horn and persistent pain in rats. J Neurosci Res. 2012;90:1096-104 pubmed publisher
Kashihara T, Nakada T, Shimojo H, Horiuchi Hirose M, Gomi S, Shibazaki T, et al. Chronic receptor-mediated activation of Gi/o proteins alters basal t-tubular and sarcolemmal L-type Ca²? channel activity through phosphatases in heart failure. Am J Physiol Heart Circ Physiol. 2012;302:H1645-54 pubmed publisher
Fernandes V, Barahona M, Recio P, Martínez Saénz A, Ribeiro A, CONTRERAS C, et al. Mechanisms involved in testosterone-induced relaxation to the pig urinary bladder neck. Steroids. 2012;77:394-402 pubmed publisher
Das A, Pushparaj C, Bahi N, Sorolla A, Herreros J, Pamplona R, et al. Functional expression of voltage-gated calcium channels in human melanoma. Pigment Cell Melanoma Res. 2012;25:200-12 pubmed publisher
Kim Y, Chung S, Lee Y, Kim E, Ahn D. Increase of L-type Ca2+ current by protease-activated receptor 2 activation contributes to augmentation of spontaneous uterine contractility in pregnant rats. Biochem Biophys Res Commun. 2012;418:167-72 pubmed publisher
Okada Y, Imendra K, Miyazaki T, Hotokezaka H, Fujiyama R, Toda K. High extracellular Ca2+ stimulates Ca2+-activated Cl- currents in frog parathyroid cells through the mediation of arachidonic acid cascade. PLoS ONE. 2011;6:e19158 pubmed publisher
Sekiguchi Tonosaki M, Obata M, Haruki A, Himi T, Kosaka J. Acetylcholine induces Ca2+ signaling in chicken retinal pigmented epithelial cells during dedifferentiation. Am J Physiol Cell Physiol. 2009;296:C1195-206 pubmed publisher
Chevalier J, Derkinderen P, Gomes P, Thinard R, Naveilhan P, Vanden Berghe P, et al. Activity-dependent regulation of tyrosine hydroxylase expression in the enteric nervous system. J Physiol. 2008;586:1963-75 pubmed publisher
Ferrante J, Luchowski E, Rutledge A, Triggle D. Binding of A 1,4-dihydropyridine calcium channel activator, (-) S Bay K 8644, to cardiac preparations. Biochem Biophys Res Commun. 1989;158:149-54 pubmed
product information
Catalog Number :
B133
Product Name :
(S)-(−)-Bay K8644
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC), solid
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA