This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Phenoxybenzamine hydrochloride
catalog :
B019
citations: 35
Reference
Bdioui S, Verdi J, Pierre N, Trinquet E, Roux T, Kenakin T. The pharmacologic characterization of allosteric molecules: Gq protein activation. J Recept Signal Transduct Res. 2019;39:106-113 pubmed publisher
Lynch C, Zhao J, Huang R, Xiao J, Li L, Heyward S, et al. Quantitative high-throughput identification of drugs as modulators of human constitutive androstane receptor. Sci Rep. 2015;5:10405 pubmed publisher
Jia J, Zeng X, Yang L, Bai J. The epinephrine increases tyrosine hydroxylase expression through upregulating thioredoxin-1 in PC12 cells. Biochimie. 2015;115:52-8 pubmed publisher
Telegdy G, Adamik A. Neurotransmitter-mediated anxiogenic action of PACAP-38 in rats. Behav Brain Res. 2015;281:333-8 pubmed publisher
Telegdy G, Foris L, Jászberényi M. Urocortin 3 administration impairs fear motivated learning in mice is mediated by transmitters. Behav Brain Res. 2014;270:326-9 pubmed publisher
Unett D, Gatlin J, Anthony T, Buzard D, Chang S, Chen C, et al. Kinetics of 5-HT2B receptor signaling: profound agonist-dependent effects on signaling onset and duration. J Pharmacol Exp Ther. 2013;347:645-59 pubmed publisher
Scholten A, Cisco R, Vriens M, Cohen J, Mitmaker E, Liu C, et al. Pheochromocytoma crisis is not a surgical emergency. J Clin Endocrinol Metab. 2013;98:581-91 pubmed publisher
Akindele A, Awodele O, Alagbaoso A, Adeyemi O. Antidiarrhoeal activity of DAS-77 (a herbal preparation). Nig Q J Hosp Med. 2011;21:317-23 pubmed
Siddiqi H, Yang H, Laird A, Fox A, Doherty G, Miller B, et al. Utility of oral nicardipine and magnesium sulfate infusion during preparation and resection of pheochromocytomas. Surgery. 2012;152:1027-36 pubmed publisher
Telegdy G, Schally A. Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice. Behav Brain Res. 2012;233:232-6 pubmed publisher
Polavarapu H, Kurian A, Josloff R. Is dexmedetomidine the agent of choice in the resection of pheochromocytoma?. Am Surg. 2012;78:E127-8 pubmed
Groeben H. [Preoperative ?-receptor block in patients with pheochromocytoma? Against]. Chirurg. 2012;83:551-4 pubmed publisher
Sisson J, Giordano T, Avram A. Three endocrine neoplasms: an unusual combination of pheochromocytoma, pituitary adenoma, and papillary thyroid carcinoma. Thyroid. 2012;22:430-6 pubmed publisher
Petronilho A, Reis G, Dias Q, Fais R, Prado W. Antinociceptive effect of stimulating the zona incerta with glutamate in rats. Pharmacol Biochem Behav. 2012;101:360-8 pubmed publisher
. Phenoxybenzamine hydrochloride. Rep Carcinog. 2011;12:344-5 pubmed
Jugovac I, Antapli M, Markan S. Anesthesia and pheochromocytoma. Int Anesthesiol Clin. 2011;49:57-61 pubmed publisher
Navarro I, Molina M, Civera M, Ascaso J, Real J, Carmena R. [Catecholamine-induced cardiomyopathy triggered by pheochromocytoma]. Endocrinol Nutr. 2011;58:204-6 pubmed publisher
James M, Keifer J. Posterior optic nerve ischemic neuropathy in the setting of phenoxybenzamine therapy after uneventful spinal fusion. J Neurosurg Anesthesiol. 2011;23:169-70 pubmed publisher
Zhu Y, He H, Su T, Wu Y, Wang W, Zhao J, et al. Selective α1-adrenoceptor antagonist (controlled release tablets) in preoperative management of pheochromocytoma. Endocrine. 2010;38:254-9 pubmed publisher
Welch B, Atwell T, Nichols D, Wass C, Callstrom M, Leibovich B, et al. Percutaneous image-guided adrenal cryoablation: procedural considerations and technical success. Radiology. 2011;258:301-7 pubmed publisher
Chang M, Smith S, Thorpe A, Barratt M, Karim F. Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping. Mol Pain. 2010;6:56 pubmed publisher
Nisa S, Blokpoel M, Robertson B, Tyndall J, Lun S, Bishai W, et al. Targeting the chromosome partitioning protein ParA in tuberculosis drug discovery. J Antimicrob Chemother. 2010;65:2347-58 pubmed publisher
Yau J, Li J, Tam V, Fung L, Yeung C, Chan K, et al. Phaeochromocytoma in the Hong Kong Chinese population. Hong Kong Med J. 2010;16:252-6 pubmed
Weismann D, Kleinbrahm K, Hu K, Fassnacht M, Frantz S, Ertl G, et al. Prevention of hypertensive crises in rats induced by acute and chronic norepinephrine excess. Horm Metab Res. 2010;42:803-8 pubmed publisher
Cadirci E, Suleyman H, Hacimuftuoglu A, Halici Z, Akcay F. Indirect role of beta2-adrenergic receptors in the mechanism of analgesic action of nonsteroidal antiinflammatory drugs. Crit Care Med. 2010;38:1860-7 pubmed publisher
Black J, Leff P, Shankley N, Wood J. An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimation. 1985. Br J Pharmacol. 2010;160 Suppl 1:S54-64 pubmed publisher
Eisenhofer G, Bornstein S. Surgery: Risks of hemodynamic instability in pheochromocytoma. Nat Rev Endocrinol. 2010;6:301-2 pubmed publisher
Silveira J, Dias Q, Del Bel E, Prado W. Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats. Mol Pain. 2010;6:17 pubmed publisher
Bruynzeel H, Feelders R, Groenland T, van den Meiracker A, van Eijck C, Lange J, et al. Risk Factors for Hemodynamic Instability during Surgery for Pheochromocytoma. J Clin Endocrinol Metab. 2010;95:678-85 pubmed publisher
James L, Griffiths C, Garthwaite J, Bellamy T. Inhibition of nitric oxide-activated guanylyl cyclase by calmodulin antagonists. Br J Pharmacol. 2009;158:1454-64 pubmed publisher
Srinivasan C, Sachdeva R, Morrow W, Gossett J, Chipman C, Imamura M, et al. Standardized management improves outcomes after the Norwood procedure. Congenit Heart Dis. 2009;4:329-37 pubmed publisher
Ning Y, Sanchez E. In vivo evidence for the generation of a glucocorticoid receptor-heat shock protein-90 complex incapable of binding hormone by the calmodulin antagonist phenoxybenzamine. Mol Endocrinol. 1996;10:14-23 pubmed
. Phenoxybenzamine and phenoxybenzamine hydrochloride. IARC Monogr Eval Carcinog Risk Chem Hum. 1980;24:185-94 pubmed
Kalsner S. Is there feedback regulation of neurotransmitter release by autoreceptors?. Biochem Pharmacol. 1985;34:4085-97 pubmed
van Zwieten P, Timmermans P. Receptor subtypes involved in the action of calcium entry blockers. Ann N Y Acad Sci. 1988;522:351-60 pubmed
product information
Catalog Number :
B019
Product Name :
Phenoxybenzamine hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥97%, powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA