This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Amyloid β Protein Fragment 1-42
catalog :
A9810
citations: 35
Reference
Nitzan K, Benhamron S, Valitsky M, Kesner E, Lichtenstein M, Ben Zvi A, et al. Mitochondrial Transfer Ameliorates Cognitive Deficits, Neuronal Loss, and Gliosis in Alzheimer's Disease Mice. J Alzheimers Dis. 2019;72:587-604 pubmed publisher
Jiang X, Chen L, Lan Z, Xiong F, Xu X, Yin Y, et al. Icariin Ameliorates Amyloid Pathologies by Maintaining Homeostasis of Autophagic Systems in Aβ1-42-Injected Rats. Neurochem Res. 2019;44:2708-2722 pubmed publisher
Gao Y, Yan Y, Fang Q, Zhang N, Kumar G, Zhang J, et al. The Rho kinase inhibitor fasudil attenuates Aβ1-42-induced apoptosis via the ASK1/JNK signal pathway in primary cultures of hippocampal neurons. Metab Brain Dis. 2019;34:1787-1801 pubmed publisher
Wang K, Ye X, Huang T, Yang X, Zou L. Optogenetics-induced activation of glutamate receptors improves memory function in mice with Alzheimer's disease. Neural Regen Res. 2019;14:2147-2155 pubmed publisher
Gregosa A, Vinuesa A, Todero M, Pomilio C, Rossi S, Bentivegna M, et al. Periodic dietary restriction ameliorates amyloid pathology and cognitive impairment in PDAPP-J20 mice: Potential implication of glial autophagy. Neurobiol Dis. 2019;:104542 pubmed publisher
Unsal Tan O, Tuylu Kucukkilinc T, Ayazgok B, Balkan A, Ozadali Sari K. Synthesis, molecular docking, and biological evaluation of novel 2-pyrazoline derivatives as multifunctional agents for the treatment of Alzheimer's disease. Medchemcomm. 2019;10:1018-1026 pubmed publisher
Kawarabayashi T, Terakawa T, Takahashi A, Hasegawa H, Narita S, Sato K, et al. Oral Immunization with Soybean Storage Protein Containing Amyloid-β 4-10 Prevents Spatial Learning Decline. J Alzheimers Dis. 2019;70:487-503 pubmed publisher
Sadegh Malvajerd S, Izadi Z, Azadi A, Kurd M, Derakhshankhah H, Sharifzadeh M, et al. Neuroprotective Potential of Curcumin-Loaded Nanostructured Lipid Carrier in an Animal Model of Alzheimer's Disease: Behavioral and Biochemical Evidence. J Alzheimers Dis. 2019;69:671-686 pubmed publisher
Wu K, Zhang R, Lu Y, Wen L, Li Y, Duan R, et al. Lin28B regulates the fate of grafted mesenchymal stem cells and enhances their protective effects against Alzheimer's disease by upregulating IGF-2. J Cell Physiol. 2019;234:21860-21876 pubmed publisher
Abdshahzadeh H, Golshani M, Nadri H, Saberi Kia I, Abdolahi Z, Forootanfar H, et al. 3-Aryl Coumarin Derivatives Bearing Aminoalkoxy Moiety as Multi-Target-Directed Ligands against Alzheimer's Disease. Chem Biodivers. 2019;16:e1800436 pubmed publisher
Yang B, Cai Z, Zhang W, Yin D, Zhao W, Yang M. Autophagy alleviates the decrease in proliferation of amyloid β1‑42‑treated bone marrow mesenchymal stem cells via the AKT/mTOR signaling pathway. Mol Med Rep. 2019;19:4091-4100 pubmed publisher
Wani A, Gupta M, Ahmad M, Shah A, Ahsan A, Qazi P, et al. Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway. Autophagy. 2019;:1-19 pubmed publisher
Yang Z, Kuboyama T, Tohda C. Naringenin promotes microglial M2 polarization and Aβ degradation enzyme expression. Phytother Res. 2019;33:1114-1121 pubmed publisher
Nishioka C, Liang H, Barsamian B, Sun S. Amyloid-beta induced retrograde axonal degeneration in a mouse tauopathy model. Neuroimage. 2019;189:180-191 pubmed publisher
Salehi N, Mirjalili B, Nadri H, Abdolahi Z, Forootanfar H, Samzadeh Kermani A, et al. Synthesis and biological evaluation of new N-benzylpyridinium-based benzoheterocycles as potential anti-Alzheimer's agents. Bioorg Chem. 2018;83:559-568 pubmed publisher
Lu C, Ma J, Luo Z, Tai Q, Wang P, Guan P. Transferrin is responsible for mediating the effects of iron ions on the regulation of anterior pharynx-defective-1α/β and Presenilin 1 expression via PGE2 and PGD2 at the early stage of Alzheimer's Disease. Aging (Albany NY). 2018;10:3117-3135 pubmed publisher
Wang L, Shi F, Xu W, Cao Y, Li N, Li M, et al. The Down-Expression of ACE and IDE Exacerbates Exogenous Amyloid-β Neurotoxicity in CB2R-/- Mice. J Alzheimers Dis. 2018;64:957-971 pubmed publisher
Abedinifar F, Farnia S, Mahdavi M, Nadri H, Moradi A, Ghasemi J, et al. Synthesis and cholinesterase inhibitory activity of new 2-benzofuran carboxamide-benzylpyridinum salts. Bioorg Chem. 2018;80:180-188 pubmed publisher
Jalili Baleh L, Nadri H, Forootanfar H, Samzadeh Kermani A, Kuçukkilinç T, Ayazgok B, et al. Novel 3-phenylcoumarin-lipoic acid conjugates as multi-functional agents for potential treatment of Alzheimer's disease. Bioorg Chem. 2018;79:223-234 pubmed publisher
Kantar Gok D, Hidisoglu E, Ocak G, Er H, Acun A, Yargicoglu P. Protective role of rosmarinic acid on amyloid beta 42-induced echoic memory decline: Implication of oxidative stress and cholinergic impairment. Neurochem Int. 2018;118:1-13 pubmed publisher
Navabi S, Sarkaki A, Mansouri E, Badavi M, Ghadiri A, Farbood Y. The effects of betulinic acid on neurobehavioral activity, electrophysiology and histological changes in an animal model of the Alzheimer's disease. Behav Brain Res. 2018;337:99-106 pubmed publisher
Xu J, Li D, Zheng T, Lu Y. β-amyloid expression in age-related cataract lens epithelia and the effect of β-amyloid on oxidative damage in human lens epithelial cells. Mol Vis. 2017;23:1015-1028 pubmed
Zheng S, Gong Z, Lu C, Wang P. Prostaglandin I2 is responsible for ameliorating prostaglandin E2 stress in stimulating the expression of tumor necrosis factor α in a β-amyloid protein -dependent mechanism. Oncotarget. 2017;8:102801-102819 pubmed publisher
Yao Y, Chen X, Bao Y, Wu Y. Puerarin inhibits ??amyloid peptide 1?42?induced tau hyperphosphorylation via the Wnt/??catenin signaling pathway. Mol Med Rep. 2017;16:9081-9085 pubmed publisher
Yang Z, Kuboyama T, Tohda C. A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer's Disease and Its Target Molecule. Front Pharmacol. 2017;8:340 pubmed publisher
Baker J, Shelton L, Zheng D, Favretto F, Nordhues B, Darling A, et al. Human cyclophilin 40 unravels neurotoxic amyloids. PLoS Biol. 2017;15:e2001336 pubmed publisher
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Hu C, Wang P, Zhang S, Ren L, Lv Y, Yin R, et al. Neuroprotective effect of melatonin on soluble Aβ1-42-induced cortical neurodegeneration via Reelin-Dab1 signaling pathway. Neurol Res. 2017;39:621-631 pubmed publisher
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Shu L, Sun W, Li L, Xu Z, Lin L, Xie P, et al. Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease. BMC Genomics. 2016;17:381 pubmed publisher
Wang X, Zhang X, Zhou T, Li N, Jang C, Xiao Z, et al. Elevated Neuronal Excitability Due to Modulation of the Voltage-Gated Sodium Channel Nav1.6 by Aβ1-42. Front Neurosci. 2016;10:94 pubmed publisher
Wang P, Guan P, Yu X, Zhang L, Su Y, Wang Z. Prostaglandin I₂ Attenuates Prostaglandin E₂-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent Mechanism. Sci Rep. 2016;6:20879 pubmed publisher
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product information
Catalog Number :
A9810
Product Name :
Amyloid β Protein Fragment 1-42
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA