Zhang S, Tang Y, Chen Y, Zhang J, Wei Y. Boronic acid-modified polyhedral oligomeric silsesquioxanes on polydopamine-coated magnetized graphene oxide for selective and high-capacity extraction of the catecholamines epinephrine, dopamine and isoprenaline. Mikrochim Acta. 2020;187:77 pubmed publisher

Cooper S, March J, Sabbatini A, Hill S, Jörg M, Scammells P, et al. The effect of two selective A1 -receptor agonists and the bitopic ligand VCP746 on heart rate and regional vascular conductance in conscious rats. Br J Pharmacol. 2020;177:346-359 pubmed publisher

Erdogmus S, Storch U, Danner L, Becker J, Winter M, Ziegler N, et al. Helix 8 is the essential structural motif of mechanosensitive GPCRs. Nat Commun. 2019;10:5784 pubmed publisher

Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, et al. ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer. Mol Ther Oncolytics. 2019;14:299-312 pubmed publisher

Pryor R, Norvaišas P, Marinos G, Best L, Thingholm L, Quintaneiro L, et al. Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy. Cell. 2019;178:1299-1312.e29 pubmed publisher

Buter J, Cheng T, Ghanem M, Grootemaat A, Raman S, Feng X, et al. Mycobacterium tuberculosis releases an antacid that remodels phagosomes. Nat Chem Biol. 2019;15:889-899 pubmed publisher

Su W, Chen X, Zhu W, Yu J, Li W, Li Y, et al. The cAMP-Adenosine Feedback Loop Maintains the Suppressive Function of Regulatory T Cells. J Immunol. 2019;203:1436-1446 pubmed publisher

Huang W, Xu Y, Zhang Y, Zhang P, Zhang Q, Zhang Z, et al. Metabolomics-driven identification of adenosine deaminase as therapeutic target in a mouse model of Parkinson's disease. J Neurochem. 2019;150:282-295 pubmed publisher

Cristallini C, Vaccari G, Barbani N, Cibrario Rocchietti E, Barberis R, Falzone M, et al. Cardioprotection of PLGA/gelatine cardiac patches functionalised with adenosine in a large animal model of ischaemia and reperfusion injury: A feasibility study. J Tissue Eng Regen Med. 2019;13:1253-1264 pubmed publisher

Selberg S, Blokhina D, Aatonen M, Koivisto P, Siltanen A, Mervaala E, et al. Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site. Cell Rep. 2019;26:3762-3771.e5 pubmed publisher

Xu K, Cooney K, Shin E, Wang L, Deppen J, Ginn S, et al. Adenosine from a biologic source regulates neutrophil extracellular traps (NETs). J Leukoc Biol. 2019;105:1225-1234 pubmed publisher

Cooper S, Soave M, Jörg M, Scammells P, Woolard J, Hill S. Probe dependence of allosteric enhancers on the binding affinity of adenosine A1 -receptor agonists at rat and human A1 -receptors measured using NanoBRET. Br J Pharmacol. 2019;176:864-878 pubmed publisher

Nybo S, Lamberts J. Integrated use of LC/MS/MS and LC/Q-TOF/MS targeted metabolomics with automated label-free microscopy for quantification of purine metabolites in cultured mammalian cells. Purinergic Signal. 2019;15:17-25 pubmed publisher

Morató X, Gonçalves F, Lopes J, Jauregui O, Soler C, Fernández Dueñas V, et al. Chronic adenosine A2A receptor blockade induces locomotor sensitization and potentiates striatal LTD IN GPR37-deficient mice. J Neurochem. 2019;148:796-809 pubmed publisher

Brandon A, Liao B, Diakanastasis B, Parker B, Raddatz K, McManus S, et al. Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance. Cell Metab. 2019;29:183-191.e7 pubmed publisher

Ito K, Seino M, Miyasaka Y, Hatori K. Inorganic polyphosphate hydrolysis catalyzed by skeletal muscular actomyosin complexes is uncoupled with motility. Biochim Biophys Acta Proteins Proteom. 2018;1866:1224-1231 pubmed publisher

Hall J, Frenguelli B. The combination of ribose and adenine promotes adenosine release and attenuates the intensity and frequency of epileptiform activity in hippocampal slices: Evidence for the rapid depletion of cellular ATP during electrographic seizures. J Neurochem. 2018;147:178-189 pubmed publisher

Hitzel J, Lee E, Zhang Y, Bibli S, Li X, Zukunft S, et al. Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. Nat Commun. 2018;9:2292 pubmed publisher

Madry C, Kyrargyri V, Arancibia Carcamo I, Jolivet R, Kohsaka S, Bryan R, et al. Microglial Ramification, Surveillance, and Interleukin-1? Release Are Regulated by the Two-Pore Domain K+ Channel THIK-1. Neuron. 2018;97:299-312.e6 pubmed publisher

Manninen H, Rotola Pukkila M, Aisala H, Hopia A, Laaksonen T. Free amino acids and 5'-nucleotides in Finnish forest mushrooms. Food Chem. 2018;247:23-28 pubmed publisher

Qu C, Wang L, Lin H, Shang E, Tang Y, Yue S, et al. Hierarchical identification of bioactive components in a medicinal herb by preparative high-performance liquid chromatography and selective knock-out strategy. J Pharm Biomed Anal. 2017;135:206-216 pubmed publisher

Nadal L, Garcia N, Hurtado E, Simó A, Tomas M, Lanuza M, et al. Presynaptic muscarinic acetylcholine autoreceptors (M1, M2 and M4 subtypes), adenosine receptors (A1 and A2A) and tropomyosin-related kinase B receptor (TrkB) modulate the developmental synapse elimination process at the neuromuscular junction. Mol Brain. 2016;9:67 pubmed publisher

Passerini V, Ozeri Galai E, de Pagter M, Donnelly N, Schmalbrock S, Kloosterman W, et al. The presence of extra chromosomes leads to genomic instability. Nat Commun. 2016;7:10754 pubmed publisher

Ye D, Li T, Liu D, Zhang X, Zheng Z. P accumulation and physiological responses to different high P regimes in Polygonum hydropiper for understanding a P-phytoremediation strategy. Sci Rep. 2015;5:17835 pubmed publisher

Obis T, Hurtado E, Nadal L, Tomàs M, Priego M, Simon A, et al. The novel protein kinase C epsilon isoform modulates acetylcholine release in the rat neuromuscular junction. Mol Brain. 2015;8:80 pubmed publisher

Zhong F, Yang J, Tong Z, Chen L, Fan L, Wang F, et al. Guggulsterone inhibits human cholangiocarcinoma Sk-ChA-1 and Mz-ChA-1 cell growth by inducing caspase-dependent apoptosis and downregulation of survivin and Bcl-2 expression. Oncol Lett. 2015;10:1416-1422 pubmed

Schneider G, Glaser T, Lameu C, Abdelbaset Ismail A, Sellers Z, Moniuszko M, et al. Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells. Mol Cancer. 2015;14:201 pubmed publisher

Eyer K, Root K, Verboket P, Dittrich P. Detection of Infertility-related Neutralizing Antibodies with a Cell-free Microfluidic Method. Sci Rep. 2015;5:16551 pubmed publisher

Nicholls S, Ruotolo G, Brewer H, Kane J, Wang M, Krueger K, et al. Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib. J Am Coll Cardiol. 2015;66:2201-2210 pubmed publisher

Murakami H, Otani E, Iwata T, Esaka Y, Aoyama T, Kawasaki M, et al. Simple Pretreatment and HILIC Separation for LC-ESI-MS/MS Determination of Adenosine in Human Plasma. Anal Sci. 2015;31:1189-92 pubmed publisher

Meng B, Gao W, Wei J, Pu L, Tang Z, Guo C. Quercetin Increases Hepatic Homocysteine Remethylation and Transsulfuration in Rats Fed a Methionine-Enriched Diet. Biomed Res Int. 2015;2015:815210 pubmed publisher

Savage K, Stough C, Byrne G, Scholey A, Bousman C, Murphy J, et al. Kava for the treatment of generalised anxiety disorder (K-GAD): study protocol for a randomised controlled trial. Trials. 2015;16:493 pubmed publisher

Deisting W, Raum T, Kufer P, Baeuerle P, Münz M. Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110. PLoS ONE. 2015;10:e0141669 pubmed publisher

Schneider M, Kasanetz F, Lynch D, Friemel C, Lassalle O, Hurst D, et al. Enhanced Functional Activity of the Cannabinoid Type-1 Receptor Mediates Adolescent Behavior. J Neurosci. 2015;35:13975-88 pubmed publisher

Wagner M, Ohlund L, Shiao T, Vézina A, Annabi B, Roy R, et al. Isotope-labeled differential profiling of metabolites using N-benzoyloxysuccinimide derivatization coupled to liquid chromatography/high-resolution tandem mass spectrometry. Rapid Commun Mass Spectrom. 2015;29:1632-40 pubmed publisher

Vaz S, Lérias S, Parreira S, Diógenes M, Sebastião A. Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes. Purinergic Signal. 2015;11:607-12 pubmed publisher

Lemos C, Pinheiro B, Beleza R, Marques J, Rodrigues R, Cunha R, et al. Adenosine A2B receptor activation stimulates glucose uptake in the mouse forebrain. Purinergic Signal. 2015;11:561-9 pubmed publisher

Kelkar M, Martin S. PKA antagonizes CLASP-dependent microtubule stabilization to re-localize Pom1 and buffer cell size upon glucose limitation. Nat Commun. 2015;6:8445 pubmed publisher

Wang Q, Yang X, Yang X, Wang K, Zhang H, Liu P. An enzyme-free colorimetric assay using hybridization chain reaction amplification and split aptamers. Analyst. 2015;140:7657-62 pubmed publisher

Rukdee N, Rojsanga P, Phechkrajang C. Development and Validation of LC-MS/MS Method for Quantitative Determination of Adenosine, Guanosine, Xanthine and Uric acid in Widely Consumed Vegetables in Thailand. Nat Prod Commun. 2015;10:1435-7 pubmed

Gondouin B, Jourde Chiche N, Sallée M, Dou L, Cerini C, Loundou A, et al. Plasma Xanthine Oxidase Activity Is Predictive of Cardiovascular Disease in Patients with Chronic Kidney Disease, Independently of Uric Acid Levels. Nephron. 2015;131:167-74 pubmed publisher

Dubey R, Fingerle J, Gillespie D, Mi Z, Rosselli M, Imthurn B, et al. Adenosine Attenuates Human Coronary Artery Smooth Muscle Cell Proliferation by Inhibiting Multiple Signaling Pathways That Converge on Cyclin D. Hypertension. 2015;66:1207-19 pubmed publisher

Wang P, Yuan X, Wang Y, Zhao H, Sun X, Zheng Q. Licochalcone C induces apoptosis via B-cell lymphoma 2 family proteins in T24 cells. Mol Med Rep. 2015;12:7623-8 pubmed publisher

Burke T, Markwald R, McHill A, Chinoy E, Snider J, Bessman S, et al. Effects of caffeine on the human circadian clock in vivo and in vitro. Sci Transl Med. 2015;7:305ra146 pubmed publisher

Wu Y, Luo H, Kou H, Wen Y, Shen L, Pei L, et al. Prenatal caffeine exposure induced a lower level of fetal blood leptin mainly via placental mechanism. Toxicol Appl Pharmacol. 2015;289:109-16 pubmed publisher

Kanzaki Y, Yamauchi Y, Morita H, Hayashi M, Komori T, Ukimura A, et al. Presence of Postsystolic Shortening Increases the Likelihood of Coronary Artery Disease: A Rest Electrocardiography-Gated Myocardial Perfusion SPECT Study. J Nucl Med. 2015;56:1889-94 pubmed publisher

De Felice B, Manfellotto F, Palumbo A, Troisi J, Zullo F, Di Carlo C, et al. Genome-wide microRNA expression profiling in placentas from pregnant women exposed to BPA. BMC Med Genomics. 2015;8:56 pubmed publisher

Zhou Z, Xiao L, Xiang Y, Zhou J, Tong A. A general approach for rational design of fluorescent DNA aptazyme sensors based on target-induced unfolding of DNA hairpins. Anal Chim Acta. 2015;889:179-86 pubmed publisher

Meimoun P, Abouth S, Clerc J, Elmkies F, Martis S, Luycx Bore A, et al. Usefulness of two-dimensional longitudinal strain pattern to predict left ventricular recovery and in-hospital complications after acute anterior myocardial infarction treated successfully by primary angioplasty. J Am Soc Echocardiogr. 2015;28:1366-75 pubmed publisher

Dass S, Holloway C, Cochlin L, Rider O, Mahmod M, Robson M, et al. No Evidence of Myocardial Oxygen Deprivation in Nonischemic Heart Failure. Circ Heart Fail. 2015;8:1088-93 pubmed publisher

Chen C, Syu J, Way T, Huang L, Kuo S, Lin C, et al. BC3EE2,9B, a synthetic carbazole derivative, upregulates autophagy and synergistically sensitizes human GBM8901 glioblastoma cells to temozolomide. Int J Mol Med. 2015;36:1244-52 pubmed publisher

Certal M, Vinhas A, Pinheiro A, Ferreirinha F, Barros Barbosa A, Silva I, et al. Calcium signaling and the novel anti-proliferative effect of the UTP-sensitive P2Y11 receptor in rat cardiac myofibroblasts. Cell Calcium. 2015;58:518-33 pubmed publisher

Wang Q, Ye M, Xu L, Shi Z. A reversed-phase/hydrophilic interaction mixed-mode C18-Diol stationary phase for multiple applications. Anal Chim Acta. 2015;888:182-90 pubmed publisher

Feng R, Fan C, Liu Q, Liu Z, Zhang W, Li Y, et al. Crude triterpenoid saponins from Ilex latifolia (Da Ye Dong Qing) ameliorate lipid accumulation by inhibiting SREBP expression via activation of AMPK in a non-alcoholic fatty liver disease model. Chin Med. 2015;10:23 pubmed publisher

Galvão J, Elvas F, Martins T, Cordeiro M, Ambrósio A, Santiago A. Adenosine A3 receptor activation is neuroprotective against retinal neurodegeneration. Exp Eye Res. 2015;140:65-74 pubmed publisher

Willmann L, Erbes T, Halbach S, Brummer T, Jager M, Hirschfeld M, et al. Exometabolom analysis of breast cancer cell lines: Metabolic signature. Sci Rep. 2015;5:13374 pubmed publisher

Zhao W, Wang Y, Wang Y, Gao N, Han Z, Yu H. Potential anti-cancer effect of curcumin in human lung squamous cell carcinoma. Thorac Cancer. 2015;6:508-16 pubmed publisher

Agarwal V, Bell G, Nam J, Bartel D. Predicting effective microRNA target sites in mammalian mRNAs. elife. 2015;4: pubmed publisher

Arai T, Ishiguro K, Kimura S, Sakaguchi Y, Suzuki T, Suzuki T. Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly. Proc Natl Acad Sci U S A. 2015;112:E4707-16 pubmed publisher

Eichin D, Laurila J, Jalkanen S, Salmi M. CD73 Activity is Dispensable for the Polarization of M2 Macrophages. PLoS ONE. 2015;10:e0134721 pubmed publisher

Tenorio M, Luchsinger C, Mardones G. Protein kinase A activity is necessary for fission and fusion of Golgi to endoplasmic reticulum retrograde tubules. PLoS ONE. 2015;10:e0135260 pubmed publisher

Unterholzner S, Rozhon W, Papacek M, Ciomas J, Lange T, Kugler K, et al. Brassinosteroids Are Master Regulators of Gibberellin Biosynthesis in Arabidopsis. Plant Cell. 2015;27:2261-72 pubmed publisher

Zou Y, Liu Y, Ruan M, Feng X, Wang J, Chu Z, et al. Cordyceps sinensis oral liquid prolongs the lifespan of the fruit fly, Drosophila melanogaster, by inhibiting oxidative stress. Int J Mol Med. 2015;36:939-46 pubmed publisher

Macle L, Khairy P, Weerasooriya R, Novak P, Verma A, Willems S, et al. Adenosine-guided pulmonary vein isolation for the treatment of paroxysmal atrial fibrillation: an international, multicentre, randomised superiority trial. Lancet. 2015;386:672-9 pubmed publisher

Läer K, Dork T, Vennemann M, Rothämel T, Klintschar M. Polymorphisms in genes of respiratory control and sudden infant death syndrome. Int J Legal Med. 2015;129:977-84 pubmed publisher

Lamm N, Maoz K, Bester A, Im M, Shewach D, Karni R, et al. Folate levels modulate oncogene-induced replication stress and tumorigenicity. EMBO Mol Med. 2015;7:1138-52 pubmed publisher

Iskierko Z, Sosnowska M, Sharma P, Benincori T, D SOUZA F, Kaminska I, et al. Extended-gate field-effect transistor (EG-FET) with molecularly imprinted polymer (MIP) film for selective inosine determination. Biosens Bioelectron. 2015;74:526-33 pubmed publisher

Orogo A, Gonzalez E, Kubli D, Baptista I, Ong S, Prolla T, et al. Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival. J Biol Chem. 2015;290:22061-75 pubmed publisher

Hinzman J, Gibson J, Tackla R, Costello M, Burmeister J, Quintero J, et al. Real-time monitoring of extracellular adenosine using enzyme-linked microelectrode arrays. Biosens Bioelectron. 2015;74:512-7 pubmed publisher

He T, Brocca Cofano E, Gillespie D, Xu C, Stock J, Ma D, et al. Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues. J Virol. 2015;89:9616-30 pubmed publisher

Zhang M, Niu F, Li K. Proflavin suppresses the growth of human osteosarcoma MG63 cells through apoptosis and autophagy. Oncol Lett. 2015;10:463-468 pubmed

Gan J, Wei X, Li Y, Wu J, Qian K, Liu B. Designer SiOâ‚‚@Au nanoshells towards sensitive and selective detection of small molecules in laser desorption ionization mass spectrometry. Nanomedicine. 2015;11:1715-23 pubmed publisher

Wu D, Ren X, Hu L, Fan D, Zheng Y, Wei Q. Electrochemical aptasensor for the detection of adenosine by using PdCu@MWCNTs-supported bienzymes as labels. Biosens Bioelectron. 2015;74:391-7 pubmed publisher

Parnham S, Gleadle J, Leong D, Grover S, Bradbrook C, Woodman R, et al. Myocardial perfusion is impaired in asymptomatic renal and liver transplant recipients: a cardiovascular magnetic resonance study. J Cardiovasc Magn Reson. 2015;17:56 pubmed publisher

Crean D, Cummins E, Bahar B, Mohan H, McMorrow J, Murphy E. Adenosine Modulates NR4A Orphan Nuclear Receptors To Attenuate Hyperinflammatory Responses in Monocytic Cells. J Immunol. 2015;195:1436-48 pubmed publisher

Chen M, Liang D, Zuo A, Shao H, Kaplan H, Sun D. An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation. PLoS ONE. 2015;10:e0132348 pubmed publisher

Ogasawara J, Izawa T, Sakurai T, Shirato K, Ishibashi Y, Ohira Y, et al. Habitual exercise training acts as a physiological stimulator for constant activation of lipolytic enzymes in rat primary white adipocytes. Biochem Biophys Res Commun. 2015;464:348-53 pubmed publisher

Johansson M, Agusti A, Llansola M, Montoliu C, Strömberg J, Malinina E, et al. GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy. Am J Physiol Gastrointest Liver Physiol. 2015;309:G400-9 pubmed publisher

Kim E, Park M, Park S, Lee E. Increased expression of the NLRP3 inflammasome components in patients with Behçet's disease. J Inflamm (Lond). 2015;12:41 pubmed publisher

Ghemlas I, Li H, Zlateska B, Klaassen R, Fernandez C, Yanofsky R, et al. Improving diagnostic precision, care and syndrome definitions using comprehensive next-generation sequencing for the inherited bone marrow failure syndromes. J Med Genet. 2015;52:575-84 pubmed publisher

Sharma B, Oh J, Kim H, Kim Y, Jeong K, Rhyu D. Anti-Obesity Effects of the Mixture of Eriobotrya japonica and Nelumbo nucifera in Adipocytes and High-Fat Diet-Induced Obese Mice. Am J Chin Med. 2015;43:681-94 pubmed publisher

Wang T, Chen Y, Ma J, Zhang X, Zhang L, Zhang Y. Ionic liquid-based zwitterionic organic polymer monolithic column for capillary hydrophilic interaction chromatography. Analyst. 2015;140:5585-92 pubmed publisher

Kabeya N, Yamamoto Y, Cummins S, Elizur A, Yazawa R, Takeuchi Y, et al. Polyunsaturated fatty acid metabolism in a marine teleost, Nibe croaker Nibea mitsukurii: Functional characterization of Fads2 desaturase and Elovl5 and Elovl4 elongases. Comp Biochem Physiol B Biochem Mol Biol. 2015;188:37-45 pubmed publisher

Yoshimi K, Kumada S, WEITEMIER A, Jo T, Inoue M. Reward-Induced Phasic Dopamine Release in the Monkey Ventral Striatum and Putamen. PLoS ONE. 2015;10:e0130443 pubmed publisher

Chen W, Wu Y, Li L, Yang M, Shen L, Liu G, et al. Adenosine accelerates the healing of diabetic ischemic ulcers by improving autophagy of endothelial progenitor cells grown on a biomaterial. Sci Rep. 2015;5:11594 pubmed publisher

Imlach W, Bhola R, May L, Christopoulos A, Christie M. A Positive Allosteric Modulator of the Adenosine A1 Receptor Selectively Inhibits Primary Afferent Synaptic Transmission in a Neuropathic Pain Model. Mol Pharmacol. 2015;88:460-8 pubmed publisher

Davis C, Ammi A, Alkayed N, Kaul S. Ultrasound stimulates formation and release of vasoactive compounds in brain endothelial cells. Am J Physiol Heart Circ Physiol. 2015;309:H583-91 pubmed publisher

Jansen S, Akintola A, Roelfsema F, van der Spoel E, Cobbaert C, Ballieux B, et al. Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism. Sci Rep. 2015;5:11525 pubmed publisher

Castilhos L, Rezer J, Ruchel J, Thorstenberg M, Jaques J, Schlemmer J, et al. Effect of Uncaria tomentosa extract on purinergic enzyme activities in lymphocytes of rats submitted to experimental adjuvant arthritis model. BMC Complement Altern Med. 2015;15:189 pubmed publisher

Scorrano S, Mergola L, Di Bello M, Lazzoi M, Vasapollo G, Del Sole R. Molecularly Imprinted Composite Membranes for Selective Detection of 2-Deoxyadenosine in Urine Samples. Int J Mol Sci. 2015;16:13746-59 pubmed publisher

Palde P, Carroll K. A universal entropy-driven mechanism for thioredoxin-target recognition. Proc Natl Acad Sci U S A. 2015;112:7960-5 pubmed publisher

Feng C, Zhu J, Sun J, Jiang W, Wang L. Hairpin assembly circuit-based fluorescence cooperative amplification strategy for enzyme-free and label-free detection of small molecule. Talanta. 2015;143:101-106 pubmed publisher

Chien C, Su M. 5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect on coronary flow in isolated rat hearts. J Biomed Sci. 2015;22:42 pubmed publisher

Otsuguro K, Tomonari Y, Otsuka S, Yamaguchi S, Kon Y, Ito S. An adenosine kinase inhibitor, ABT-702, inhibits spinal nociceptive transmission by adenosine release via equilibrative nucleoside transporters in rat. Neuropharmacology. 2015;97:160-70 pubmed publisher

Hartmann A, Albert A, Ganzera M. Effects of elevated ultraviolet radiation on primary metabolites in selected alpine algae and cyanobacteria. J Photochem Photobiol B. 2015;149:149-55 pubmed publisher

Villacrés C, Tayi V, Lattová E, Perreault H, Butler M. Low glucose depletes glycan precursors, reduces site occupancy and galactosylation of a monoclonal antibody in CHO cell culture. Biotechnol J. 2015;10:1051-66 pubmed publisher

Nakamura Y, Kikugawa S, Seki S, Takahata M, Iwasaki N, Terai H, et al. PCSK5 mutation in a patient with the VACTERL association. BMC Res Notes. 2015;8:228 pubmed publisher

Madeira M, Elvas F, Boia R, Gonçalves F, Cunha R, Ambrósio A, et al. Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure. J Neuroinflammation. 2015;12:115 pubmed publisher

Lee M, Kim E, Lee S, Kang Y, Jung C, Yoon H, et al. Dehydroepiandrosterone prevents linoleic acid-induced endothelial cell senescence by increasing autophagy. Metabolism. 2015;64:1134-45 pubmed publisher

Xue Y, Shi W, Zhu B, Gu X, Wang Y, Yan C. Polyethyleneimine-grafted boronate affinity materials for selective enrichment of cis-diol-containing compounds. Talanta. 2015;140:1-9 pubmed publisher

Clancy Thompson E, Perekslis T, Croteau W, Alexander M, Chabanet T, Turk M, et al. Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease. Cancer Immunol Res. 2015;3:956-67 pubmed publisher

Sarada S, Titto M, Himadri P, Saumya S, Vijayalakshmi V. Curcumin prophylaxis mitigates the incidence of hypobaric hypoxia-induced altered ion channels expression and impaired tight junction proteins integrity in rat brain. J Neuroinflammation. 2015;12:113 pubmed publisher

Daghir Wojtkowiak E, Wiczling P, Bocian S, Kubik Å, KoÅ›liÅ„ski P, Buszewski B, et al. Least absolute shrinkage and selection operator and dimensionality reduction techniques in quantitative structure retention relationship modeling of retention in hydrophilic interaction liquid chromatography. J Chromatogr A. 2015;1403:54-62 pubmed publisher

Yamamoto A, Hasui K, Matsuo H, Okuda K, Abe M, Matsumoto K, et al. Bongkrekic acid analogue, lacking one of the carboxylic groups of its parent compound, shows moderate but pH-insensitive inhibitory effects on the mitochondrial ADP/ATP carrier. Chem Biol Drug Des. 2015;86:1304-22 pubmed publisher

Lu X, Dittgen J, Piślewska Bednarek M, Molina A, Schneider B, Svatoš A, et al. Mutant Allele-Specific Uncoupling of PENETRATION3 Functions Reveals Engagement of the ATP-Binding Cassette Transporter in Distinct Tryptophan Metabolic Pathways. Plant Physiol. 2015;168:814-27 pubmed publisher

Currivan S, Macak J, Jandera P. Polymethacrylate monolithic columns for hydrophilic interaction liquid chromatography prepared using a secondary surface polymerization. J Chromatogr A. 2015;1402:82-93 pubmed publisher

Allum F, Shao X, Guénard F, Simon M, Busche S, Caron M, et al. Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants. Nat Commun. 2015;6:7211 pubmed publisher

Chen Y, Bao Y, Zhang J, Woehrle T, Sumi Y, Ledderose S, et al. Inhibition of Neutrophils by Hypertonic Saline Involves Pannexin-1, CD39, CD73, and Other Ectonucleotidases. Shock. 2015;44:221-7 pubmed publisher

Silva I, Ferreirinha F, Magalhães Cardoso M, Silva Ramos M, Correia de Sá P. Activation of P2Y6 Receptors Facilitates Nonneuronal Adenosine Triphosphate and Acetylcholine Release from Urothelium with the Lamina Propria of Men with Bladder Outlet Obstruction. J Urol. 2015;194:1146-54 pubmed publisher

Koseoglu S, Peters C, Fitch Tewfik J, Aisiku O, Danglot L, Galli T, et al. VAMP-7 links granule exocytosis to actin reorganization during platelet activation. Blood. 2015;126:651-60 pubmed publisher

Kienitz M, Mergia E, Pott L. NCI-H295R cell line as in vitro model of hyperaldosteronism lacks functional KCNJ5 (GIRK4; Kir3.4) channels. Mol Cell Endocrinol. 2015;412:272-80 pubmed publisher

Bruzzese L, Rostain J, Nee L, Condo J, Mottola G, Adjriou N, et al. Effect of hyperoxic and hyperbaric conditions on the adenosinergic pathway and CD26 expression in rat. J Appl Physiol (1985). 2015;119:140-7 pubmed publisher

Torres Fuentes J, Rios M, Moreno R. Involvement of a P2X7 Receptor in the Acrosome Reaction Induced by ATP in Rat Spermatozoa. J Cell Physiol. 2015;230:3068-75 pubmed publisher

Territo P, Maluccio M, Riley A, McCarthy B, Fletcher J, Tann M, et al. Evaluation of 11C-acetate and 18F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma. BMC Med Imaging. 2015;15:15 pubmed publisher

Haraguchi A, Kinoshita K, Fukai M, Koyama K. A novel nucleoside from the edible mushroom, Tricholoma japonicum. J Nat Med. 2015;69:584-8 pubmed publisher

Du X, Ou X, Song T, Zhang W, Cong F, Zhang S, et al. Adenosine A2B receptor stimulates angiogenesis by inducing VEGF and eNOS in human microvascular endothelial cells. Exp Biol Med (Maywood). 2015;240:1472-9 pubmed publisher

Yang Y, Bucan V, Baehre H, von der Ohe J, Otte A, Hass R. Acquisition of new tumor cell properties by MSC-derived exosomes. Int J Oncol. 2015;47:244-52 pubmed publisher

Wakita M, Kotani N, Akaike N. Tetrodotoxin abruptly blocks excitatory neurotransmission in mammalian CNS. Toxicon. 2015;103:12-8 pubmed publisher

Jarosch M, Gebhardt C, Fano S, Huchzermeyer C, Ul Haq R, Behrens C, et al. Early adenosine release contributes to hypoxia-induced disruption of stimulus-induced sharp wave-ripple complexes in rat hippocampal area CA3. Eur J Neurosci. 2015;42:1808-17 pubmed publisher

Tong L, Chen Z, Jiang Z, Sun M, Li L, Liu J, et al. Fluorescent sensing of pyrophosphate anion in synovial fluid based on DNA-attached magnetic nanoparticles. Biosens Bioelectron. 2015;72:51-5 pubmed publisher

Hussey S, Mizrachi E, Groover A, Berger D, Myburg A. Genome-wide mapping of histone H3 lysine 4 trimethylation in Eucalyptus grandis developing xylem. BMC Plant Biol. 2015;15:117 pubmed publisher

Kirbas A, Cüre M, Kalkan Y, Cure E, Tumkaya L, Sahin O, et al. Effect of infliximab on renal injury due to methotrexate in rat. Iran J Kidney Dis. 2015;9:221-9 pubmed

Yang Y, Wang H, Lv X, Wang Q, Zhao H, Yang F, et al. Involvement of cAMP-PKA pathway in adenosine A1 and A2A receptor-mediated regulation of acetaldehyde-induced activation of HSCs. Biochimie. 2015;115:59-70 pubmed publisher

Erratico C, Zheng X, Rydén A, Marsh G, Maho W, Covaci A. Human hydroxylated metabolites of BDE-47 and BDE-99 are glucuronidated and sulfated in vitro. Toxicol Lett. 2015;236:98-109 pubmed publisher

Oberholzer M, Saada E, Hill K. Cyclic AMP Regulates Social Behavior in African Trypanosomes. MBio. 2015;6:e01954-14 pubmed publisher

Parodi B, Rossi S, Morando S, Cordano C, Bragoni A, Motta C, et al. Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS. Acta Neuropathol. 2015;130:279-95 pubmed publisher

Song K, Kim S, Choe Y, Jung W, Lee S, Chang S, et al. Integrated cardiac magnetic resonance imaging with coronary magnetic resonance angiography, stress-perfusion, and delayed-enhancement imaging for the detection of occult coronary artery disease in asymptomatic individuals. Int J Cardiovasc Imaging. 2015;31 Suppl 1:77-89 pubmed publisher

Pernet E, Brunet J, Guillemot L, Chignard M, Touqui L, Wu Y. Staphylococcus aureus Adenosine Inhibits sPLA2-IIA-Mediated Host Killing in the Airways. J Immunol. 2015;194:5312-9 pubmed publisher

Zhang Y, Yang Z, Feng Y, Li R, Zhang Q, Geng H, et al. Effects of coarse chalk dust particles (2.5-10 μm) on respiratory burst and oxidative stress in alveolar macrophages. Environ Sci Pollut Res Int. 2015;22:12450-7 pubmed publisher

Trieu B, Kramár E, Cox C, Jia Y, Wang W, Gall C, et al. Pronounced differences in signal processing and synaptic plasticity between piriform-hippocampal network stages: a prominent role for adenosine. J Physiol. 2015;593:2889-907 pubmed publisher

Bhalla N, Formisano N, Miodek A, Jain A, Di Lorenzo M, Pula G, et al. Plasmonic ruler on field-effect devices for kinase drug discovery applications. Biosens Bioelectron. 2015;71:121-128 pubmed publisher

Liu R, Nahon D, le Roy B, Lenselink E, Ijzerman A. Scanning mutagenesis in a yeast system delineates the role of the NPxxY(x)(5,6)F motif and helix 8 of the adenosine A(2B) receptor in G protein coupling. Biochem Pharmacol. 2015;95:290-300 pubmed publisher

Crecelius A, Kirby B, Hearon C, Luckasen G, Larson D, Dinenno F. Contracting human skeletal muscle maintains the ability to blunt α1 -adrenergic vasoconstriction during KIR channel and Na(+) /K(+) -ATPase inhibition. J Physiol. 2015;593:2735-51 pubmed publisher

Calgaroto N, da Costa P, Cardoso A, Pereira L, Vieira J, Dalenogare D, et al. Vitamin D₃ prevents the increase in ectonucleotidase activities and ameliorates lipid profile in type 1 diabetic rats. Mol Cell Biochem. 2015;405:11-21 pubmed publisher

Santafe M, Priego M, Obis T, Garcia N, Tomas M, Lanuza M, et al. Adenosine receptors and muscarinic receptors cooperate in acetylcholine release modulation in the neuromuscular synapse. Eur J Neurosci. 2015;42:1775-87 pubmed publisher

Sugimoto S, Arita Morioka K, Mizunoe Y, Yamanaka K, Ogura T. Thioflavin T as a fluorescence probe for monitoring RNA metabolism at molecular and cellular levels. Nucleic Acids Res. 2015;43:e92 pubmed publisher

D Andrea I, Fardella V, Fardella S, Pallante F, Ghigo A, Iacobucci R, et al. Lack of kinase-independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling. EMBO Mol Med. 2015;7:904-17 pubmed publisher

Alsharif K, Thomas M, Judge H, Khan H, Prince L, Sabroe I, et al. Ticagrelor potentiates adenosine-induced stimulation of neutrophil chemotaxis and phagocytosis. Vascul Pharmacol. 2015;71:201-7 pubmed publisher

Shin H, Jang H, Han J, Park H, Lee J, Kim S, et al. Targeted next-generation sequencing for the genetic diagnosis of dysferlinopathy. Neuromuscul Disord. 2015;25:502-10 pubmed publisher

Ho Y, Cheng J, Chiou L. Impairment of adenylyl cyclase-mediated glutamatergic synaptic plasticity in the periaqueductal grey in a rat model of neuropathic pain. J Physiol. 2015;593:2955-73 pubmed publisher

Studzińska S, Buszewski B. Different approaches to quantitative structure-retention relationships in the prediction of oligonucleotide retention. J Sep Sci. 2015;38:2076-84 pubmed publisher

Matsuda T, Kubo A, Taguchi T, Mizumura K. ATP decreases mechanical sensitivity of muscle thin-fiber afferents in rats. Neurosci Res. 2015;97:36-44 pubmed publisher

Gavriilaki E, Yuan X, Ye Z, Ambinder A, Shanbhag S, Streiff M, et al. Modified Ham test for atypical hemolytic uremic syndrome. Blood. 2015;125:3637-46 pubmed publisher

Cividini F, Filoni D, Pesi R, Allegrini S, Camici M, Tozzi M. IMP-GMP specific cytosolic 5'-nucleotidase regulates nucleotide pool and prodrug metabolism. Biochim Biophys Acta. 2015;1850:1354-61 pubmed publisher

Li J, Chen Z, Zhao J, Fang L, Fang R, Xiao J, et al. Difference in microRNA expression and editing profile of lung tissues from different pig breeds related to immune responses to HP-PRRSV. Sci Rep. 2015;5:9549 pubmed publisher

Sekimoto R, Fukuda S, Maeda N, Tsushima Y, Matsuda K, Mori T, et al. Visualized macrophage dynamics and significance of S100A8 in obese fat. Proc Natl Acad Sci U S A. 2015;112:E2058-66 pubmed publisher

George J, Gonçalves F, Cristóvão G, Rodrigues L, Meyer Fernandes J, Gonçalves T, et al. Different danger signals differently impact on microglial proliferation through alterations of ATP release and extracellular metabolism. Glia. 2015;63:1636-45 pubmed publisher

Leung E, Chan W. Noninvasive measurement of aristolochic acid-DNA adducts in urine samples from aristolochic acid-treated rats by liquid chromatography coupled tandem mass spectrometry: evidence for DNA repair by nucleotide-excision repair mechanisms. Mutat Res. 2014;766-767:1-6 pubmed publisher

Ramos V, Bettencourt N, Silva J, Ferreira N, Chiribiri A, Schuster A, et al. Noninvasive anatomical and functional assessment of coronary artery disease. Rev Port Cardiol. 2015;34:223-32 pubmed publisher

Swami R, Singh I, Jeengar M, Naidu V, Khan W, Sistla R. Adenosine conjugated lipidic nanoparticles for enhanced tumor targeting. Int J Pharm. 2015;486:287-96 pubmed publisher

de Souza R, Bretanha L, Dalmarco E, Pizzolatti M, Fröde T. Modulatory effect of Senecio brasiliensis (Spreng) Less. in a murine model of inflammation induced by carrageenan into the pleural cavity. J Ethnopharmacol. 2015;168:373-9 pubmed publisher

Li Q, Wu Y, Fang S, Wang L, Qi H, Zhang Y, et al. BCR/ABL oncogene-induced PI3K signaling pathway leads to chronic myeloid leukemia pathogenesis by impairing immuno-modulatory function of hemangioblasts. Cancer Gene Ther. 2015;22:227-37 pubmed publisher

Yang T, Gao X, Sandberg M, Zollbrecht C, Zhang X, Hezel M, et al. Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses. Diabetologia. 2015;58:1610-20 pubmed publisher

Calvo Álvarez E, Stamatakis K, Punzon C, Alvarez Velilla R, Tejería A, Escudero Martínez J, et al. Infrared fluorescent imaging as a potent tool for in vitro, ex vivo and in vivo models of visceral leishmaniasis. PLoS Negl Trop Dis. 2015;9:e0003666 pubmed publisher

Chen J, Shi Q, Wang Y, Li Z, Wang S. Dereplication of known nucleobase and nucleoside compounds in natural product extracts by capillary electrophoresis-high resolution mass spectrometry. Molecules. 2015;20:5423-37 pubmed publisher

Helenius M, Vattulainen S, Orcholski M, Aho J, Komulainen A, Taimen P, et al. Suppression of endothelial CD39/ENTPD1 is associated with pulmonary vascular remodeling in pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2015;308:L1046-57 pubmed publisher

Nandi S, Chakraborty A, Panda A, Ray S, Kar R, Bhunia A, et al. Interaction of ATP with a small heat shock protein from Mycobacterium leprae: effect on its structure and function. PLoS Negl Trop Dis. 2015;9:e0003661 pubmed publisher

Scharf M, Miske R, Heidenreich F, Giess R, Landwehr P, Blöcker I, et al. Neuronal Na+/K+ ATPase is an autoantibody target in paraneoplastic neurologic syndrome. Neurology. 2015;84:1673-9 pubmed publisher

Fujii N, McGinn R, Halili L, Singh M, Kondo N, Kenny G. Cutaneous vascular and sweating responses to intradermal administration of ATP: a role for nitric oxide synthase and cyclooxygenase?. J Physiol. 2015;593:2515-25 pubmed publisher

Ye Y, Gong H, Wang X, Wu J, Wang S, Yuan J, et al. Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic Pressure Overload-induced Cardiac Hypertrophy and Remodeling in Male Mice. J Cardiovasc Pharmacol. 2015;65:628-39 pubmed publisher

Nakazato R, Takarada T, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, et al. Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP. J Cell Physiol. 2015;230:2510-21 pubmed publisher

Liu J, He X, Wang K, He D, Wang Y, Mao Y, et al. A highly sensitive electrochemiluminescence assay for protein kinase based on double-quenching of graphene quantum dots by G-quadruplex-hemin and gold nanoparticles. Biosens Bioelectron. 2015;70:54-60 pubmed publisher

Ring S, Pushkarevskaya A, Schild H, Probst H, Jendrossek V, Wirsdörfer F, et al. Regulatory T cell-derived adenosine induces dendritic cell migration through the Epac-Rap1 pathway. J Immunol. 2015;194:3735-44 pubmed publisher

Ng S, Higashimori H, Tolman M, Yang Y. Suppression of adenosine 2a receptor (A2aR)-mediated adenosine signaling improves disease phenotypes in a mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2015;267:115-22 pubmed publisher

Shu Y, Lang J, Breitbach Z, Qiu H, Smuts J, Kiyono Shimobe M, et al. Separation of therapeutic peptides with cyclofructan and glycopeptide based columns in hydrophilic interaction liquid chromatography. J Chromatogr A. 2015;1390:50-61 pubmed publisher

Zanin R, da Silva G, Erig T, Sperotto N, Leite C, Coutinho Silva R, et al. Decrease of serum adenine nucleotide hydrolysis in an irritant contact dermatitis mice model: potential P2X7R involvement. Mol Cell Biochem. 2015;404:221-8 pubmed publisher

Martinez R, Stein J, Krostag A, Nelson A, Marken J, Menon V, et al. Genome engineering of isogenic human ES cells to model autism disorders. Nucleic Acids Res. 2015;43:e65 pubmed publisher

Regassa A, Kim W. Transcriptome analysis of hen preadipocytes treated with an adipogenic cocktail (DMIOA) with or without 20(S)-hydroxylcholesterol. BMC Genomics. 2015;16:91 pubmed publisher

Lambertz U, Oviedo Ovando M, Vasconcelos E, Unrau P, Myler P, Reiner N. Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal RNA Packaging. BMC Genomics. 2015;16:151 pubmed publisher

Lebon G, Edwards P, Leslie A, Tate C. Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor. Mol Pharmacol. 2015;87:907-15 pubmed publisher

Zhang W, Cai J, Chen S, Zheng X, Hu S, Dong W, et al. Paclitaxel resistance in MCF-7/PTX cells is reversed by paeonol through suppression of the SET/phosphatidylinositol 3-kinase/Akt pathway. Mol Med Rep. 2015;12:1506-14 pubmed publisher

Thomas D, Herold N, Keppler O, Geisslinger G, Ferreirós N. Quantitation of endogenous nucleoside triphosphates and nucleosides in human cells by liquid chromatography tandem mass spectrometry. Anal Bioanal Chem. 2015;407:3693-704 pubmed publisher

Lougiakis N, Marakos P, Pouli N, Fragopoulou E, Tenta R. Synthesis of new nebularine analogues and their inhibitory activity against adenosine deaminase. Chem Pharm Bull (Tokyo). 2015;63:134-42 pubmed publisher

Haeusler D, Grassinger L, Fuchshuber F, Hörleinsberger W, Höftberger R, Leisser I, et al. Hide and seek: a comparative autoradiographic in vitro investigation of the adenosine A3 receptor. Eur J Nucl Med Mol Imaging. 2015;42:928-39 pubmed publisher

Jing X, He C, Yang Y, Duan C. A metal-organic tetrahedron as a redox vehicle to encapsulate organic dyes for photocatalytic proton reduction. J Am Chem Soc. 2015;137:3967-74 pubmed publisher

Palumbo P, Miconi G, Cinque B, La Torre C, Lombardi F, Zoccali G, et al. In vitro evaluation of different methods of handling human liposuction aspirate and their effect on adipocytes and adipose derived stem cells. J Cell Physiol. 2015;230:1974-81 pubmed publisher

Li P, Gao Y, Cao J, Wang W, Chen Y, Zhang G, et al. CD39+ regulatory T cells attenuate allergic airway inflammation. Clin Exp Allergy. 2015;45:1126-37 pubmed publisher

Liang T, Fu Q, Shen A, Wang H, Jin Y, Xin H, et al. Preparation and chromatographic evaluation of a newly designed steviol glycoside modified-silica stationary phase in hydrophilic interaction liquid chromatography and reversed phase liquid chromatography. J Chromatogr A. 2015;1388:110-8 pubmed publisher

Mousavi S, Panjehpour M, Izadpanahi M, Aghaei M. Expression of adenosine receptor subclasses in malignant and adjacent normal human prostate tissues. Prostate. 2015;75:735-47 pubmed publisher

Kliner D, Wang L, Winger D, Follansbee W, Soman P. A prospective evaluation of the repeatability of left ventricular ejection fraction measurement by gated SPECT. J Nucl Cardiol. 2015;22:1237-43 pubmed publisher

Beech J, Saleh L, Frentzel J, Figler H, Correa I, Baker B, et al. Multivalent site-specific phage modification enhances the binding affinity of receptor ligands. Bioconjug Chem. 2015;26:529-36 pubmed publisher

Franceschini A, Capece M, Chiozzi P, Falzoni S, Sanz J, Sarti A, et al. The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein. FASEB J. 2015;29:2450-61 pubmed publisher

Chrobak P, Charlebois R, Rejtar P, El Bikai R, Allard B, Stagg J. CD73 plays a protective role in collagen-induced arthritis. J Immunol. 2015;194:2487-92 pubmed publisher

Byrne A, Elliott C, Hoffmann R, Baillie G. The activity of cAMP-phosphodiesterase 4D7 (PDE4D7) is regulated by protein kinase A-dependent phosphorylation within its unique N-terminus. FEBS Lett. 2015;589:750-5 pubmed publisher

Bingol K, Bruschweiler Li L, Yu C, Somogyi A, Zhang F, Bruschweiler R. Metabolomics beyond spectroscopic databases: a combined MS/NMR strategy for the rapid identification of new metabolites in complex mixtures. Anal Chem. 2015;87:3864-70 pubmed publisher

Beavis P, Milenkovski N, Henderson M, John L, Allard B, Loi S, et al. Adenosine Receptor 2A Blockade Increases the Efficacy of Anti-PD-1 through Enhanced Antitumor T-cell Responses. Cancer Immunol Res. 2015;3:506-17 pubmed publisher

Mahajan S, Manetsch R, Merkler D, Stevens S. Synthesis and evaluation of a novel adenosine-ribose probe for global-scale profiling of nucleoside and nucleotide-binding proteins. PLoS ONE. 2015;10:e0115644 pubmed publisher

Sacramento J, Ribeiro M, Yubero S, Melo B, Obeso A, Guarino M, et al. Disclosing caffeine action on insulin sensitivity: effects on rat skeletal muscle. Eur J Pharm Sci. 2015;70:107-16 pubmed publisher

Choi I, Cho J, Lee M, Jang I. Enzymatic conversion of ATP to adenosine contributes to ATP-induced inhibition of glutamate release in rat medullary dorsal horn neurons. Neuropharmacology. 2015;93:94-102 pubmed publisher

Booker S, Pires N, Cobb S, Soares da Silva P, Vida I. Carbamazepine and oxcarbazepine, but not eslicarbazepine, enhance excitatory synaptic transmission onto hippocampal CA1 pyramidal cells through an antagonist action at adenosine A1 receptors. Neuropharmacology. 2015;93:103-15 pubmed publisher

Baron L, Gombault A, Fanny M, Villeret B, Savigny F, Guillou N, et al. The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine. Cell Death Dis. 2015;6:e1629 pubmed publisher

Loram L, Strand K, Taylor F, Sloane E, van Dam A, Rieger J, et al. Adenosine 2A receptor agonism: A single intrathecal administration attenuates motor paralysis in experimental autoimmune encephalopathy in rats. Brain Behav Immun. 2015;46:50-4 pubmed publisher

Sajjadi M, Gholamrezaei A, Daryani N. No association between serum adenosine deaminase activity and disease activity in Crohn's disease. Dig Dis Sci. 2015;60:1755-60 pubmed publisher

Lopatár J, Dale N, Frenguelli B. Pannexin-1-mediated ATP release from area CA3 drives mGlu5-dependent neuronal oscillations. Neuropharmacology. 2015;93:219-28 pubmed publisher

Keifer J, Zheng Z. Coincidence detection in a neural correlate of classical conditioning is initiated by bidirectional 3-phosphoinositide-dependent kinase-1 signalling and modulated by adenosine receptors. J Physiol. 2015;593:1581-95 pubmed publisher

Li D, Li Y, Li X, Bie Z, Pan X, Zhang Q, et al. A high boronate avidity monolithic capillary for the selective enrichment of trace glycoproteins. J Chromatogr A. 2015;1384:88-96 pubmed publisher

Taheri T, Saberi Nik H, Seyed N, Doustdari F, Etemadzadeh M, Torkashvand F, et al. Generation of stable L. major(+EGFP-LUC) and simultaneous comparison between EGFP and luciferase sensitivity. Exp Parasitol. 2015;150:44-55 pubmed publisher

Liao C, Lin Y, Kuo C. Effect of high-fat diet on hepatic proteomics of hamsters. J Agric Food Chem. 2015;63:1869-81 pubmed publisher

Kohno K, Ohashi E, Sano O, Kusano H, Kunikata T, Arai N, et al. Anti-inflammatory effects of adenosine N1-oxide. J Inflamm (Lond). 2015;12:2 pubmed publisher

Tanaka N, Takahashi Y, Ishihara H, Kawakami T, Ono H. Usefulness and safety of intracoronary administration of nicorandil for evaluating fractional flow reserve in Japanese patients. Clin Cardiol. 2015;38:20-4 pubmed publisher

Najafabadi M, Khayamian T, Hashemian Z. Aptamer-conjugated magnetic nanoparticles for extraction of adenosine from urine followed by electrospray ion mobility spectrometry. J Pharm Biomed Anal. 2015;107:244-50 pubmed publisher

Asfahl K, Walsh J, Gilbert K, Schuster M. Non-social adaptation defers a tragedy of the commons in Pseudomonas aeruginosa quorum sensing. ISME J. 2015;9:1734-46 pubmed publisher

Huang Y, Zheng L, Yang H, Chen J, Wang Y, Li H, et al. Measuring the dynamics of cyclic adenosine monophosphate level in living cells induced by low-level laser irradiation using bioluminescence resonance energy transfer. J Biomed Opt. 2015;20:051029 pubmed publisher

Qiu J, Zhou Z, He Z, Zhao R, Zhang X, Yang L, et al. Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells. Drug Des Devel Ther. 2015;9:349-417 pubmed publisher

Sakamaki H, Uchida T, Lim L, Takeuchi T. Evaluation of column hardware on liquid chromatography-mass spectrometry of phosphorylated compounds. J Chromatogr A. 2015;1381:125-31 pubmed publisher

Rauck R, North J, Eisenach J. Intrathecal clonidine and adenosine: effects on pain and sensory processing in patients with chronic regional pain syndrome. Pain. 2015;156:88-95 pubmed publisher

Rudich N, Dekel O, Sagi Eisenberg R. Down-regulation of the A3 adenosine receptor in human mast cells upregulates mediators of angiogenesis and remodeling. Mol Immunol. 2015;65:25-33 pubmed publisher

Stuijfzand W, Uusitalo V, Kero T, Danad I, Rijnierse M, Saraste A, et al. Relative flow reserve derived from quantitative perfusion imaging may not outperform stress myocardial blood flow for identification of hemodynamically significant coronary artery disease. Circ Cardiovasc Imaging. 2015;8: pubmed publisher

Watkins A, Yasuda K, Wilson G, Aprahamian T, Xie Y, Maganto Garcia E, et al. IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis. J Immunol. 2015;194:1467-79 pubmed publisher

Ferrari L, Bogen O, Reichling D, Levine J. Accounting for the delay in the transition from acute to chronic pain: axonal and nuclear mechanisms. J Neurosci. 2015;35:495-507 pubmed publisher

Sun K, Zhang Y, Bogdanov M, Wu H, Song A, Li J, et al. Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity. Blood. 2015;125:1643-52 pubmed publisher

Ahuja K, Arora G, Khare P, Selvapandiyan A. Selective elimination of Leptomonas from the in vitro co-culture with Leishmania. Parasitol Int. 2015;64:1-5 pubmed publisher

Luan G, Gao Q, Zhai F, Zhou J, Liu C, Chen Y, et al. Adenosine kinase expression in cortical dysplasia with balloon cells: analysis of developmental lineage of cell types. J Neuropathol Exp Neurol. 2015;74:132-47 pubmed publisher

Godier A, Taylor G, Gaussem P. Inefficacy of platelet transfusion to reverse ticagrelor. N Engl J Med. 2015;372:196-7 pubmed publisher

Jha B, Seo I, Kong H, Suh S, Suh M, Baek W. Tigecycline inhibits proliferation of Acanthamoeba castellanii. Parasitol Res. 2015;114:1189-95 pubmed publisher

Szabo C. Editorial: Old dog, new tricks: proangiogenic effect of adenosine via stimulation of thrombospondin-1 in macrophages. J Leukoc Biol. 2015;97:3-5 pubmed publisher

Jullesson D, Johansson R, Rajan M, Stralfors P, Cedersund G. Dominant negative inhibition data should be analyzed using mathematical modeling--re-interpreting data from insulin signaling. FEBS J. 2015;282:788-802 pubmed publisher

Lewis D, Le P, Adhya S. Differential role of base pairs on gal promoters strength. J Mol Biol. 2015;427:792-806 pubmed publisher

Alder J, Stanley S, Wagner C, Hamilton M, Hanumanthu V, Armanios M. Exome sequencing identifies mutant TINF2 in a family with pulmonary fibrosis. Chest. 2015;147:1361-1368 pubmed publisher

Gault W, Enyedi B, Niethammer P. Osmotic surveillance mediates rapid wound closure through nucleotide release. J Cell Biol. 2014;207:767-82 pubmed publisher

De Luca L, Ferlini M, Visconti L. [The ATLANTIC study]. G Ital Cardiol (Rome). 2014;15:656-63 pubmed publisher

Amarnath S, Foley J, Farthing D, Gress R, Laurence A, Eckhaus M, et al. Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo. Stem Cells. 2015;33:1200-12 pubmed publisher

Yang Y, Otte A, Hass R. Human mesenchymal stroma/stem cells exchange membrane proteins and alter functionality during interaction with different tumor cell lines. Stem Cells Dev. 2015;24:1205-22 pubmed publisher

Taylor J, Anyango J, Potgieter M, Kallmeyer K, Naidoo V, Pepper M, et al. Biocompatibility and biodegradation of protein microparticle and film scaffolds made from kafirin (sorghum prolamin protein) subcutaneously implanted in rodent models. J Biomed Mater Res A. 2015;103:2582-90 pubmed publisher

Jeon J, Bersini S, Gilardi M, Dubini G, Charest J, Moretti M, et al. Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation. Proc Natl Acad Sci U S A. 2015;112:214-9 pubmed publisher

Yang L, Zhang J, He J, Qin Y, Hua D, Duan Y, et al. ABA-mediated ROS in mitochondria regulate root meristem activity by controlling PLETHORA expression in Arabidopsis. PLoS Genet. 2014;10:e1004791 pubmed publisher

Shan Y, Qiao L, Shi X, Xu G. Preparation and evaluation of a novel hybrid monolithic column based on pentafluorobenzyl imidazolium bromide ionic liquid. J Chromatogr A. 2015;1375:101-9 pubmed publisher

Lassiter K, GREENE E, Piekarski A, Faulkner O, Hargis B, Bottje W, et al. Orexin system is expressed in avian muscle cells and regulates mitochondrial dynamics. Am J Physiol Regul Integr Comp Physiol. 2015;308:R173-87 pubmed publisher

Jaffe A, Shin J, Collado Torres L, Leek J, Tao R, Li C, et al. Developmental regulation of human cortex transcription and its clinical relevance at single base resolution. Nat Neurosci. 2015;18:154-161 pubmed publisher

Koizumi H, Arito M, Endo W, Kurokawa M, Okamoto K, Omoteyama K, et al. Effects of tofacitinib on nucleic acid metabolism in human articular chondrocytes. Mod Rheumatol. 2015;25:522-7 pubmed publisher

Montone R, Hoole S, West N. Prehospital ticagrelor in ST-segment elevation myocardial infarction. N Engl J Med. 2014;371:2338-9 pubmed publisher

Parodi G, Alexopoulos D. Prehospital ticagrelor in ST-segment elevation myocardial infarction. N Engl J Med. 2014;371:2337-8 pubmed publisher

Montalescot G, Van t Hof A. Prehospital ticagrelor in ST-segment elevation myocardial infarction. N Engl J Med. 2014;371:2339 pubmed publisher

Kriisa M, Sinijärv H, Vaasa A, Enkvist E, Kostenko S, Moens U, et al. Inhibition of CREB phosphorylation by conjugates of adenosine analogues and arginine-rich peptides, inhibitors of PKA catalytic subunit. Chembiochem. 2015;16:312-9 pubmed publisher

AydoÄŸan C. Open-tubular CEC with a new triethanolamine bonded stationary phase for biomolecule separation. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;976-977:27-32 pubmed publisher

Hara K, Shirasuna K, Usui F, Karasawa T, Mizushina Y, Kimura H, et al. Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1β in macrophages. PLoS ONE. 2014;9:e113974 pubmed publisher

Bina S, Capacchione J, Munkhuu B, Muldoon S, Bunger R. Is lymphocyte adenosine a diagnostic marker of clinical malignant hyperthermia? A pilot study. Crit Care Med. 2015;43:584-93 pubmed publisher

Dominissini D. Genomics and Proteomics. Roadmap to the epitranscriptome. Science. 2014;346:1192 pubmed publisher

Singh J, Kakalij R, Kshirsagar R, Kumar B, Komakula S, Diwan P. Cognitive effects of vanillic acid against streptozotocin-induced neurodegeneration in mice. Pharm Biol. 2015;53:630-6 pubmed publisher

Wu L, Chen L, Selvaraj J, Wei Y, Wang Y, Li Y, et al. Identification of the distribution of adenosine phosphates, nucleosides and nucleobases in royal jelly. Food Chem. 2015;173:1111-8 pubmed publisher

Deshpande A, Deshpande A, Sinha A, Chen L, Chang J, Cihan A, et al. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 2014;26:896-908 pubmed publisher

Wollmann G, Paglino J, Maloney P, Ahmadi S, van den Pol A. Attenuation of vesicular stomatitis virus infection of brain using antiviral drugs and an adeno-associated virus-interferon vector. Virology. 2015;475:1-14 pubmed publisher

Liu C, Shang Q, Bai Y, Guo C, Zhu F, Zhang L, et al. Adenosine A2A receptor, a potential valuable target for controlling reoxygenated DCs-triggered inflammation. Mol Immunol. 2015;63:559-65 pubmed

Ahmad S, Elsherbiny N, Bhatia K, Elsherbini A, Fulzele S, Liou G. Inhibition of adenosine kinase attenuates inflammation and neurotoxicity in traumatic optic neuropathy. J Neuroimmunol. 2014;277:96-104 pubmed publisher

Mahamed D, Toussaint L, Bynoe M. CD73-generated adenosine is critical for immune regulation during Toxoplasma gondii infection. Infect Immun. 2015;83:721-9 pubmed publisher

Huang Y, Yan J, Li Q, Li J, Gong S, Zhou H, et al. Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5. Nucleic Acids Res. 2015;43:373-84 pubmed publisher

Ferrari L, Levine J. Plasma membrane mechanisms in a preclinical rat model of chronic pain. J Pain. 2015;16:60-6 pubmed publisher

Yang H, Xiao L, Yuan Y, Luo X, Jiang M, Ni J, et al. Procyanidin B2 inhibits NLRP3 inflammasome activation in human vascular endothelial cells. Biochem Pharmacol. 2014;92:599-606 pubmed publisher

Albert R, Kristóf E, Zahuczky G, Szatmári Tóth M, Veréb Z, Oláh B, et al. Triamcinolone regulated apopto-phagocytic gene expression patterns in the clearance of dying retinal pigment epithelial cells. A key role of Mertk in the enhanced phagocytosis. Biochim Biophys Acta. 2015;1850:435-46 pubmed publisher

Tyebji S, Saavedra A, Canas P, Pliássova A, Delgado García J, Alberch J, et al. Hyperactivation of D1 and A2A receptors contributes to cognitive dysfunction in Huntington's disease. Neurobiol Dis. 2015;74:41-57 pubmed publisher

Garcia Dorado D, García Del Blanco B, Otaegui I, Rodríguez Palomares J, Pineda V, Gimeno F, et al. Intracoronary injection of adenosine before reperfusion in patients with ST-segment elevation myocardial infarction: a randomized controlled clinical trial. Int J Cardiol. 2014;177:935-41 pubmed publisher

Holanda A, Asth L, Santos A, Guerrini R, de P Soares Rachetti V, Calo G, et al. Central adenosine A1 and A2A receptors mediate the antinociceptive effects of neuropeptide S in the mouse formalin test. Life Sci. 2015;120:8-12 pubmed publisher

Kim S, Wu S, Fang X, Neumann J, Eichhorn L, Schleifer G, et al. Postconditioning with a CpG containing oligodeoxynucleotide ameliorates myocardial infarction in a murine closed-chest model. Life Sci. 2014;119:1-8 pubmed publisher

Mishra J, Kumar A. Improvement of mitochondrial NAD(+)/FAD(+)-linked state-3 respiration by caffeine attenuates quinolinic acid induced motor impairment in rats: implications in Huntington's disease. Pharmacol Rep. 2014;66:1148-55 pubmed publisher

Song H, Adams E, Desmet G, Cabooter D. Evaluation and comparison of the kinetic performance of ultra-high performance liquid chromatography and high-performance liquid chromatography columns in hydrophilic interaction and reversed-phase liquid chromatography conditions. J Chromatogr A. 2014;1369:83-91 pubmed publisher

Takei M, Yoshida S, Kawai T, Hasegawa M, Suzuki Y. Adaptive significance of gall formation for a gall-inducing aphids on Japanese elm trees. J Insect Physiol. 2015;72:43-51 pubmed publisher

Akiba Y, Inoue T, Kaji I, Higashiyama M, Narimatsu K, Iwamoto K, et al. Short-chain fatty acid sensing in rat duodenum. J Physiol. 2015;593:585-99 pubmed publisher

Soler F, Fernández Belda F, Pérez Schindler J, Handschin C, Fuente T, Hernandez Cascales J. PDE2 activity differs in right and left rat ventricular myocardium and differentially regulates β2 adrenoceptor-mediated effects. Exp Biol Med (Maywood). 2015;240:1205-13 pubmed publisher

Laverdière I, Guillemette C, Tamouza R, Loiseau P, Peffault De Latour R, Robin M, et al. Cyclosporine and methotrexate-related pharmacogenomic predictors of acute graft-versus-host disease. Haematologica. 2015;100:275-83 pubmed publisher

Jones L, Villemant C, Starborg T, Salter A, Goddard G, Ruane P, et al. Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion. J Cell Biol. 2014;207:499-516 pubmed publisher

Ghaffari N, Sanchez Flores A, Doan R, Garcia Orozco K, Chen P, Ochoa Leyva A, et al. Novel transcriptome assembly and improved annotation of the whiteleg shrimp (Litopenaeus vannamei), a dominant crustacean in global seafood mariculture. Sci Rep. 2014;4:7081 pubmed publisher

Botta Gordon Smith S, Ursu S, Eaton S, Moncrieffe H, Wedderburn L. Correlation of low CD73 expression on synovial lymphocytes with reduced adenosine generation and higher disease severity in juvenile idiopathic arthritis. Arthritis Rheumatol. 2015;67:545-54 pubmed publisher

Little J, Ford A, Symons Liguori A, Chen Z, Janes K, Doyle T, et al. Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. Brain. 2015;138:28-35 pubmed publisher

Colucci D Amato L, Cicatiello A, Reccia M, Volpicelli F, Severino V, Russo R, et al. A targeted secretome profiling by multiplexed immunoassay revealed that secreted chemokine ligand 2 (MCP-1/CCL2) affects neural differentiation in mesencephalic neural progenitor cells. Proteomics. 2015;15:714-24 pubmed publisher

Araszkiewicz A, Grygier M, Pyda M, Rajewska J, Michalak M, Lesiak M, et al. Postconditioning reduces enzymatic infarct size and improves microvascular reperfusion in patients with ST-segment elevation myocardial infarction. Cardiology. 2014;129:250-7 pubmed publisher

Tillet S, Giraud S, Delpech P, Thuillier R, Ameteau V, Goujon J, et al. Kidney graft outcome using an anti-Xa therapeutic strategy in an experimental model of severe ischaemia-reperfusion injury. Br J Surg. 2015;102:132-42; discussion 142 pubmed publisher

Yamaoka M, Maeda N, Takayama Y, Sekimoto R, Tsushima Y, Matsuda K, et al. Adipose hypothermia in obesity and its association with period homolog 1, insulin sensitivity, and inflammation in fat. PLoS ONE. 2014;9:e112813 pubmed publisher

Cully M. Obesity: Adenosine protects from diet-induced obesity. Nat Rev Drug Discov. 2014;13:886-7 pubmed publisher

Kaku H, Cheng K, Al Abed Y, Rothstein T. A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production. J Immunol. 2014;193:5904-13 pubmed publisher

Rotllan N, Chamorro Jorganes A, Araldi E, Wanschel A, Aryal B, Aranda J, et al. Hematopoietic Akt2 deficiency attenuates the progression of atherosclerosis. FASEB J. 2015;29:597-610 pubmed publisher

Wall M, Richardson M. Localized adenosine signaling provides fine-tuned negative feedback over a wide dynamic range of neocortical network activities. J Neurophysiol. 2015;113:871-82 pubmed publisher

Francois V, Shehade H, Acolty V, Preyat N, Delrée P, Moser M, et al. Intestinal immunopathology is associated with decreased CD73-generated adenosine during lethal infection. Mucosal Immunol. 2015;8:773-84 pubmed publisher

Ernens I, Bousquenaud M, Lenoir B, Devaux Y, Wagner D. Adenosine stimulates angiogenesis by up-regulating production of thrombospondin-1 by macrophages. J Leukoc Biol. 2015;97:9-18 pubmed publisher

Tosolini M, Pont F, Bétous D, Ravet E, Ligat L, Lopez F, et al. Human monocyte recognition of adenosine-based cyclic dinucleotides unveils the A2a Gαs protein-coupled receptor tonic inhibition of mitochondrially induced cell death. Mol Cell Biol. 2015;35:479-95 pubmed publisher

Rodrigues Ribeiro R, Alvarenga E, Calió M, Paredes Gamero E, Ferreira A. Dual role of P2 receptors during osteoblast differentiation. Cell Biochem Biophys. 2015;71:1225-33 pubmed publisher

Huebbe P, Dose J, Schloesser A, Campbell G, Glüer C, Gupta Y, et al. Apolipoprotein E (APOE) genotype regulates body weight and fatty acid utilization-Studies in gene-targeted replacement mice. Mol Nutr Food Res. 2015;59:334-43 pubmed publisher

Spotnitz M, Markowitz S, Liu C, Thomas G, Ip J, Liez J, et al. Mechanisms and clinical significance of adenosine-induced dormant accessory pathway conduction after catheter ablation. Circ Arrhythm Electrophysiol. 2014;7:1136-43 pubmed publisher

COON S, Rajendran V, Schwartz J, Singh S. Glucose-dependent insulinotropic polypeptide-mediated signaling pathways enhance apical PepT1 expression in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2015;308:G56-62 pubmed publisher

Neumann J, Thompson J, Raval A, Cohan C, Koronowski K, Perez Pinzon M. Increased BDNF protein expression after ischemic or PKC epsilon preconditioning promotes electrophysiologic changes that lead to neuroprotection. J Cereb Blood Flow Metab. 2015;35:121-30 pubmed publisher

Chaston D, Haddock R, Howitt L, Morton S, Brown R, Matthaei K, et al. Perturbation of chemical coupling by an endothelial Cx40 mutant attenuates endothelium-dependent vasodilation by KCa channels and elevates blood pressure in mice. Pflugers Arch. 2015;467:1997-2009 pubmed publisher

Kip A, Balasegaram M, Beijnen J, Schellens J, de Vries P, Dorlo T. Systematic review of biomarkers to monitor therapeutic response in leishmaniasis. Antimicrob Agents Chemother. 2015;59:1-14 pubmed publisher

Becker M, Hundemer A, Zwicker C, Altiok E, Krohn T, Mottaghy F, et al. Detection of coronary artery disease in postmenopausal women: the significance of integrated stress imaging tests in a 4-year prognostic study. Clin Res Cardiol. 2015;104:258-71 pubmed publisher

Xiao Y, Huang W, Zhang J, Peng C, Xia M, Ling W. Increased plasma S-adenosylhomocysteine-accelerated atherosclerosis is associated with epigenetic regulation of endoplasmic reticulum stress in apoE-/- mice. Arterioscler Thromb Vasc Biol. 2015;35:60-70 pubmed publisher

Kusek J, Yang Q, Witek M, Gruber C, Nanoff C, Freissmuth M. Chaperoning of the A1-adenosine receptor by endogenous adenosine - an extension of the retaliatory metabolite concept. Mol Pharmacol. 2015;87:39-51 pubmed publisher

O Neill C, Levis S, Schreiner D, Amat J, Maier S, Bachtell R. Effects of adolescent caffeine consumption on cocaine sensitivity. Neuropsychopharmacology. 2015;40:813-21 pubmed publisher

Karmouty Quintana H, Philip K, Acero L, Chen N, Weng T, Molina J, et al. Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension. FASEB J. 2015;29:50-60 pubmed publisher

Gnad T, Scheibler S, von Kügelgen I, Scheele C, Kilić A, Glöde A, et al. Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors. Nature. 2014;516:395-9 pubmed publisher

Koopman J, Marshall J, Bhatiya A, Eguale T, Kwiek J, Gunn J. Inhibition of Salmonella enterica biofilm formation using small-molecule adenosine mimetics. Antimicrob Agents Chemother. 2015;59:76-84 pubmed publisher

Sholokh M, Zamotaiev O, Das R, Postupalenko V, Richert L, Dujardin D, et al. Fluorescent amino acid undergoing excited state intramolecular proton transfer for site-specific probing and imaging of peptide interactions. J Phys Chem B. 2015;119:2585-95 pubmed publisher

Chiu G, Freund G. Modulation of neuroimmunity by adenosine and its receptors: metabolism to mental illness. Metabolism. 2014;63:1491-8 pubmed publisher

Shen F, Huang W, Huang J, Xiong J, Yang Y, Wu K, et al. Decreased N(6)-methyladenosine in peripheral blood RNA from diabetic patients is associated with FTO expression rather than ALKBH5. J Clin Endocrinol Metab. 2015;100:E148-54 pubmed publisher

Kavanagh K, Schreiner D, Levis S, O Neill C, Bachtell R. Role of adenosine receptor subtypes in methamphetamine reward and reinforcement. Neuropharmacology. 2015;89:265-73 pubmed publisher

Greene T, Lyde R, Bailey S, Lambert M, Zhai L, Sabatino D, et al. Apoptotic effects of platelet factor VIII on megakaryopoiesis: implications for a modified human FVIII for platelet-based gene therapy. J Thromb Haemost. 2014;12:2102-12 pubmed publisher

Wong R, Schlichter L. PKA reduces the rat and human KCa3.1 current, CaM binding, and Ca2+ signaling, which requires Ser332/334 in the CaM-binding C terminus. J Neurosci. 2014;34:13371-83 pubmed publisher

Fernández Dueñas V, Gómez Soler M, López Cano M, Taura J, Ledent C, Watanabe M, et al. Uncovering caffeine's adenosine A2A receptor inverse agonism in experimental parkinsonism. ACS Chem Biol. 2014;9:2496-501 pubmed publisher

Kim D, Bynoe M. A2A Adenosine Receptor Regulates the Human Blood-Brain Barrier Permeability. Mol Neurobiol. 2015;52:664-78 pubmed publisher

Muldoon P, Chen J, Harenza J, Abdullah R, Sim Selley L, Cravatt B, et al. Inhibition of monoacylglycerol lipase reduces nicotine withdrawal. Br J Pharmacol. 2015;172:869-82 pubmed publisher

Marechal A, Laaniste A, El Debs R, Dugas V, Demesmay C. Versatile ene-thiol photoclick reaction for preparation of multimodal monolithic silica capillary columns. J Chromatogr A. 2014;1365:140-7 pubmed publisher

Trincavelli M, Daniele S, Giacomelli C, Taliani S, Da Settimo F, Cosimelli B, et al. Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. Biochim Biophys Acta. 2014;1843:2957-66 pubmed publisher

Cure E, Kirbas A, Tumkaya L, Cure M, Sahin O, Kalkan Y, et al. Effect of infliximab against cisplatin-induced nephrotoxicity. Saudi Med J. 2014;35:953-8 pubmed

Janzon M, James S, Cannon C, Storey R, Mellström C, Nicolau J, et al. Health economic analysis of ticagrelor in patients with acute coronary syndromes intended for non-invasive therapy. Heart. 2015;101:119-25 pubmed publisher

Narukawa Y, Komori M, Niimura A, Noguchi H, Kiuchi F. Two new diterpenoids from Leonotis leonurus R. Br. J Nat Med. 2015;69:130-4 pubmed publisher

Ross A, Venton B. Adenosine transiently modulates stimulated dopamine release in the caudate-putamen via A1 receptors. J Neurochem. 2015;132:51-60 pubmed publisher

Hines K, Ballard B, Marshall D, McLean J. Structural mass spectrometry of tissue extracts to distinguish cancerous and non-cancerous breast diseases. Mol Biosyst. 2014;10:2827-37 pubmed publisher

Yu W, Sun X, Robson S, Hill W. ADP-induced bladder contractility is mediated by P2Y12 receptor and temporally regulated by ectonucleotidases and adenosine signaling. FASEB J. 2014;28:5288-98 pubmed publisher

Metsola J, Maksimow M, Ojaniemi M, Metsola H, Marttila Ichihara F, Vuolteenaho R, et al. Postnatal development and LPS responsiveness of pulmonary adenosine receptor expression and of adenosine-metabolizing enzymes in mice. Pediatr Res. 2014;76:515-21 pubmed publisher

Hoffmann K, Lutz D, Straßburger J, Baqi Y, Müller C, von Kügelgen I. Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12 -receptor. J Thromb Haemost. 2014;12:1898-905 pubmed publisher

Franco D, Markus R. The cellular state determines the effect of melatonin on the survival of mixed cerebellar cell culture. PLoS ONE. 2014;9:e106332 pubmed publisher

Tung N, Suzuki M, Uto T, Morinaga O, Kwofie K, Ammah N, et al. Anti-trypanosomal activity of diarylheptanoids isolated from the bark of Alnus japonica. Am J Chin Med. 2014;42:1245-60 pubmed publisher

Mrkalić E, Jelić R, Klisurić O, Matović Z. Synthesis of novel palladium(II) complexes with oxalic acid diamide derivatives and their interaction with nucleosides and proteins. Structural, solution, and computational study. Dalton Trans. 2014;43:15126-37 pubmed publisher

Montalescot G, Van t Hof A, Lapostolle F, Silvain J, Lassen J, Bolognese L, et al. Prehospital ticagrelor in ST-segment elevation myocardial infarction. N Engl J Med. 2014;371:1016-27 pubmed publisher

Chen H, Li S, Wang P, Yan S, Hu L, Pan X, et al. Endothelium-dependent and -independent relaxation of rat aorta induced by extract of Schizophyllum commune. Phytomedicine. 2014;21:1230-6 pubmed publisher

Bai X, Zhang X, Zhang Y, Wu S, Hao L, Liu R, et al. WS0701: a novel sedative-hypnotic agent acting on the adenosine system. Behav Pharmacol. 2014;25:648-60 pubmed publisher

Hadji L, Berger E, Soula H, Vidal H, Geloen A. White adipose tissue resilience to insulin deprivation and replacement. PLoS ONE. 2014;9:e106214 pubmed publisher

Noronha Matos J, Coimbra J, Sá e Sousa A, Rocha R, Marinhas J, Freitas R, et al. P2X7-induced zeiosis promotes osteogenic differentiation and mineralization of postmenopausal bone marrow-derived mesenchymal stem cells. FASEB J. 2014;28:5208-22 pubmed publisher

Mattis J, Brill J, Evans S, Lerner T, Davidson T, Hyun M, et al. Frequency-dependent, cell type-divergent signaling in the hippocamposeptal projection. J Neurosci. 2014;34:11769-80 pubmed publisher

Griffin M, Letson H, Dobson G. Adenosine, lidocaine and Mg2+ (ALM) induces a reversible hypotensive state, reduces lung edema and prevents coagulopathy in the rat model of polymicrobial sepsis. J Trauma Acute Care Surg. 2014;77:471-8 pubmed publisher

Kumar P, Smith T, Rahman K, Mells J, Thorn N, Saxena N, et al. Adiponectin modulates focal adhesion disassembly in activated hepatic stellate cells: implication for reversing hepatic fibrosis. FASEB J. 2014;28:5172-83 pubmed publisher

Wu C, Sui G, Archer S, Sassone Corsi P, Aitken K, Bagli D, et al. Local receptors as novel regulators for peripheral clock expression. FASEB J. 2014;28:4610-6 pubmed publisher

Zhang P, Ma Y, Wang Y, Ma X, Huang Y, Li R, et al. Nitric oxide and protein kinase G act on TRPC1 to inhibit 11,12-EET-induced vascular relaxation. Cardiovasc Res. 2014;104:138-46 pubmed publisher

Naydenov A, Sepers M, Swinney K, Raymond L, Palmiter R, Stella N. Genetic rescue of CB1 receptors on medium spiny neurons prevents loss of excitatory striatal synapses but not motor impairment in HD mice. Neurobiol Dis. 2014;71:140-50 pubmed publisher

Qiao L, Wang S, Li H, Shan Y, Dou A, Shi X, et al. A novel surface-confined glucaminium-based ionic liquid stationary phase for hydrophilic interaction/anion-exchange mixed-mode chromatography. J Chromatogr A. 2014;1360:240-7 pubmed publisher

Monzel M, Kuhn M, Bähre H, Seifert R, Schneider E. PDE7A1 hydrolyzes cCMP. FEBS Lett. 2014;588:3469-74 pubmed publisher

Ryzhov S, Pickup M, Chytil A, Gorska A, Zhang Q, Owens P, et al. Role of TGF-? signaling in generation of CD39+CD73+ myeloid cells in tumors. J Immunol. 2014;193:3155-64 pubmed publisher

López Del Amo V, Seco Cervera M, García Gimenez J, Whitworth A, Pallardo F, Galindo M. Mitochondrial defects and neuromuscular degeneration caused by altered expression of Drosophila Gdap1: implications for the Charcot-Marie-Tooth neuropathy. Hum Mol Genet. 2015;24:21-36 pubmed publisher

Miętus M, Nowak E, Jaciuk M, Kustosz P, Studnicka J, Nowotny M. Crystal structure of the catalytic core of Rad2: insights into the mechanism of substrate binding. Nucleic Acids Res. 2014;42:10762-75 pubmed publisher

Liang C, Du T, Zhou J, Verkhratsky A, Peng L. Ammonium increases Ca(2+) signalling and up-regulates expression of TRPC1 gene in astrocytes in primary cultures and in the in vivo brain. Neurochem Res. 2014;39:2127-35 pubmed publisher

Li C, Rainnie D. Bidirectional regulation of synaptic plasticity in the basolateral amygdala induced by the D1-like family of dopamine receptors and group II metabotropic glutamate receptors. J Physiol. 2014;592:4329-51 pubmed publisher

Liu P, Zhao L, Xu X, Liu F, Zhang W, Zhou C, et al. N6-substituted adenosine analogues, a novel class of JAK2 inhibitors, potently block STAT3 signaling in human cancer cells. Cancer Lett. 2014;354:43-57 pubmed publisher

Eme J, Rhen T, Crossley D. Adjustments in cholinergic, adrenergic and purinergic control of cardiovascular function in snapping turtle embryos (Chelydra serpentina) incubated in chronic hypoxia. J Comp Physiol B. 2014;184:891-902 pubmed publisher

Gerdt J, Blackwell H. Competition studies confirm two major barriers that can preclude the spread of resistance to quorum-sensing inhibitors in bacteria. ACS Chem Biol. 2014;9:2291-9 pubmed publisher

Clissold K, Pratt W. The effects of nucleus accumbens μ-opioid and adenosine 2A receptor stimulation and blockade on instrumental learning. Behav Brain Res. 2014;274:84-94 pubmed publisher

Deng C, Yeo H, Ye H, Liu S, Shang B, Gong P, et al. Inhibition of enterovirus 71 by adenosine analog NITD008. J Virol. 2014;88:11915-23 pubmed publisher

Abedi H, Aghaei M, Panjehpour M, Hajiahmadi S. Mitochondrial and caspase pathways are involved in the induction of apoptosis by IB-MECA in ovarian cancer cell lines. Tumour Biol. 2014;35:11027-39 pubmed publisher

Sarkaria S, Christopher M, Klco J, Ley T. Primary acute myeloid leukemia cells with IDH1 or IDH2 mutations respond to a DOT1L inhibitor in vitro. Leukemia. 2014;28:2403-6 pubmed publisher

Laourdakis C, Merino E, Neilson A, Cassera M. Comprehensive quantitative analysis of purines and pyrimidines in the human malaria parasite using ion-pairing ultra-performance liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;967:127-33 pubmed publisher

Virtanen S, Kukkonen Macchi A, Vainio M, Elima K, Härkönen P, Jalkanen S, et al. Adenosine inhibits tumor cell invasion via receptor-independent mechanisms. Mol Cancer Res. 2014;12:1863-74 pubmed publisher

Krstulja A, Lettieri S, Hall A, Delepee R, Favetta P, Agrofoglio L. Evaluation of molecularly imprinted polymers using 2',3',5'-tri-O-acyluridines as templates for pyrimidine nucleoside recognition. Anal Bioanal Chem. 2014;406:6275-84 pubmed publisher

Martins D, Brito R, Stramosk J, Batisti A, Madeira F, Turnes B, et al. Peripheral neurobiologic mechanisms of antiallodynic effect of warm water immersion therapy on persistent inflammatory pain. J Neurosci Res. 2015;93:157-66 pubmed publisher

Zhang Y, Chandra S. Oligomerization of Cysteine String Protein alpha mutants causing adult neuronal ceroid lipofuscinosis. Biochim Biophys Acta. 2014;1842:2136-46 pubmed publisher

Olah A, Toth B, Borbíró I, Sugawara K, Szöllosi A, Czifra G, et al. Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes. J Clin Invest. 2014;124:3713-24 pubmed publisher

Chatterjee C, Sparks D. P2X receptors regulate adenosine diphosphate release from hepatic cells. Purinergic Signal. 2014;10:587-93 pubmed publisher

Saha A, Biswas A, Srivastav S, Mukherjee M, Das P, Ukil A. Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis. J Immunol. 2014;193:2330-9 pubmed publisher

Quarona V, Ferri V, Chillemi A, Bolzoni M, Mancini C, Zaccarello G, et al. Unraveling the contribution of ectoenzymes to myeloma life and survival in the bone marrow niche. Ann N Y Acad Sci. 2015;1335:10-22 pubmed publisher

Sodhi P, Hartwick A. Adenosine modulates light responses of rat retinal ganglion cell photoreceptors througha cAMP-mediated pathway. J Physiol. 2014;592:4201-20 pubmed publisher

Jun J, Lee J, Shin D, Jang J. Aptamer-functionalized hybrid carbon nanofiber FET-type electrode for a highly sensitive and selective platelet-derived growth factor biosensor. ACS Appl Mater Interfaces. 2014;6:13859-65 pubmed publisher

Fujii S, Tanaka K, Ikenaka K, Yamazaki Y. Increased adenosine levels in mice expressing mutant glial fibrillary acidic protein in astrocytes result in failure of induction of LTP reversal (depotentiation) in hippocampal CA1 neurons. Brain Res. 2014;1578:1-13 pubmed publisher

van de Hoef T, Echavarría Pinto M. Physiological assessment of nonculprit stenoses during acute coronary syndromes. Am J Cardiol. 2014;114:496 pubmed publisher

Blanco S, Frye M. Role of RNA methyltransferases in tissue renewal and pathology. Curr Opin Cell Biol. 2014;31:1-7 pubmed publisher

Kono A, Coenen A, Lubbers M, Kurata A, Rossi A, Dharampal A, et al. Relative myocardial blood flow by dynamic computed tomographic perfusion imaging predicts hemodynamic significance of coronary stenosis better than absolute blood flow. Invest Radiol. 2014;49:801-7 pubmed publisher

Choi M, Kim M, Maeng H, Song I. Contribution of CNT1 and ENT1 to ribavirin uptake in human hepatocytes. Arch Pharm Res. 2015;38:904-13 pubmed publisher

Branch S, Sharma R, Beckstead M. Aging decreases L-type calcium channel currents and pacemaker firing fidelity in substantia nigra dopamine neurons. J Neurosci. 2014;34:9310-8 pubmed publisher

Ross A, Venton B. Sawhorse waveform voltammetry for selective detection of adenosine, ATP, and hydrogen peroxide. Anal Chem. 2014;86:7486-93 pubmed publisher

Jackson E, Mi Z. The guanosine-adenosine interaction exists in vivo. J Pharmacol Exp Ther. 2014;350:719-26 pubmed publisher

Liu D, Zou X, Gao M, Gu M, Xiao H. Hydrophilic organic/salt-containing aqueous two-phase solvent system for counter-current chromatography: a novel technique for separation of polar compounds. J Chromatogr A. 2014;1356:157-62 pubmed publisher

Duró E, Pallai A, Köröskényi K, Sarang Z, Szondy Z. Adenosine A3 receptors negatively regulate the engulfment-dependent apoptotic cell suppression of inflammation. Immunol Lett. 2014;162:292-301 pubmed publisher

Pereira M, Palming J, Svensson M, Rizell M, Dalenbäck J, Hammar M, et al. FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance. Metabolism. 2014;63:1198-208 pubmed publisher

Mittal D, Young A, Stannard K, Yong M, Teng M, Allard B, et al. Antimetastatic effects of blocking PD-1 and the adenosine A2A receptor. Cancer Res. 2014;74:3652-8 pubmed publisher

Eltom S, Dale N, Raemdonck K, Stevenson C, Snelgrove R, Sacitharan P, et al. Respiratory infections cause the release of extracellular vesicles: implications in exacerbation of asthma/COPD. PLoS ONE. 2014;9:e101087 pubmed publisher

Sabatino R, Antonelli A, Battistelli S, Schwendener R, Magnani M, Rossi L. Macrophage depletion by free bisphosphonates and zoledronate-loaded red blood cells. PLoS ONE. 2014;9:e101260 pubmed publisher

Quinn K, Connelly K. First report of hypersensitivity to ticagrelor. Can J Cardiol. 2014;30:957.e3-4 pubmed publisher

Kotsia A, Brilakis E, Held C, Cannon C, Steg G, Meier B, et al. Extent of coronary artery disease and outcomes after ticagrelor administration in patients with an acute coronary syndrome: Insights from the PLATelet inhibition and patient Outcomes (PLATO) trial. Am Heart J. 2014;168:68-75.e2 pubmed publisher

De Cecco C, Harris B, Schoepf U, Silverman J, McWhite C, Krazinski A, et al. Incremental value of pharmacological stress cardiac dual-energy CT over coronary CT angiography alone for the assessment of coronary artery disease in a high-risk population. AJR Am J Roentgenol. 2014;203:W70-7 pubmed publisher

Howitt L, Matthaei K, Drummond G, Hill C. Nox1 upregulates the function of vascular T-type calcium channels following chronic nitric oxide deficit. Pflugers Arch. 2015;467:727-35 pubmed publisher

Capozzi M, McCollum G, Penn J. The role of cytochrome P450 epoxygenases in retinal angiogenesis. Invest Ophthalmol Vis Sci. 2014;55:4253-60 pubmed publisher

Pomianowska E, Sandnes D, Grzyb K, Schjølberg A, Aasrum M, Tveteraas I, et al. Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma. BMC Cancer. 2014;14:413 pubmed publisher

Soares A, Costa V, Diniz C, Fresco P. Inosine strongly enhances proliferation of human C32 melanoma cells through PLC-PKC-MEK1/2-ERK1/2 and PI3K pathways. Basic Clin Pharmacol Toxicol. 2015;116:25-36 pubmed publisher

Esquivel C, Cassone B, Piermarini P. Transcriptomic evidence for a dramatic functional transition of the malpighian tubules after a blood meal in the Asian tiger mosquito Aedes albopictus. PLoS Negl Trop Dis. 2014;8:e2929 pubmed publisher

Johnston Cox H, Eisenstein A, Koupenova M, Carroll S, Ravid K. The macrophage A2B adenosine receptor regulates tissue insulin sensitivity. PLoS ONE. 2014;9:e98775 pubmed publisher

Morales Figueroa G, Márquez Gómez R, González Pantoja R, Escamilla Sánchez J, Arias Montaño J. Histamine H3 receptor activation counteracts adenosine A2A receptor-mediated enhancement of depolarization-evoked [3H]-GABA release from rat globus pallidus synaptosomes. ACS Chem Neurosci. 2014;5:637-45 pubmed publisher

Chen S, Zhou S, Zang K, Kong F, Liang D, Yan H. CD73 expression in RPE cells is associated with the suppression of conventional CD4 cell proliferation. Exp Eye Res. 2014;127:26-36 pubmed publisher

Tanaka Y, Ohashi S, Ohtsuki A, Kiyono T, Park E, Nakamura Y, et al. Adenosine, a hepato-protective component in active hexose correlated compound: its identification and iNOS suppression mechanism. Nitric Oxide. 2014;40:75-86 pubmed publisher

Le G, Essackjee H, Ballard H. Intracellular adenosine formation and release by freshly-isolated vascular endothelial cells from rat skeletal muscle: effects of hypoxia and/or acidosis. Biochem Biophys Res Commun. 2014;450:93-8 pubmed publisher

Mallik A, Cheah W, Shingo K, Ejzaki A, Takafuji M, Ihara H. Highly hydrophilic and nonionic poly(2-vinyloxazoline)-grafted silica: a novel organic phase for high-selectivity hydrophilic interaction chromatography. Anal Bioanal Chem. 2014;406:4585-93 pubmed publisher

Skårn M, Noordhuis P, Wang M, Veuger M, Kresse S, Egeland E, et al. Generation and characterization of an immortalized human mesenchymal stromal cell line. Stem Cells Dev. 2014;23:2377-89 pubmed publisher

Schlosburg J, Kinsey S, Ignatowska Jankowska B, Ramesh D, Abdullah R, Tao Q, et al. Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice. J Pharmacol Exp Ther. 2014;350:196-204 pubmed publisher

Perígolo Vicente R, Ritt K, Gonçalves de Albuquerque C, Castro Faria Neto H, Paes de Carvalho R, Giestal de Araujo E. IL-6, A1 and A2aR: a crosstalk that modulates BDNF and induces neuroprotection. Biochem Biophys Res Commun. 2014;449:477-82 pubmed publisher

Li H, Chuang A, O BRIEN J. Regulation of photoreceptor gap junction phosphorylation by adenosine in zebrafish retina. Vis Neurosci. 2014;31:237-43 pubmed publisher

Dickson E, Jensen J, Hille B. Golgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current. Proc Natl Acad Sci U S A. 2014;111:E2281-90 pubmed publisher

De Geer J, Gjerde M, Brudin L, Olsson E, Persson A, Engvall J. Large variation in blood flow between left ventricular segments, as detected by adenosine stress dynamic CT perfusion. Clin Physiol Funct Imaging. 2015;35:291-300 pubmed publisher

Pye C, Elsherbiny N, Ibrahim A, Liou G, Chadli A, Al Shabrawey M, et al. Adenosine kinase inhibition protects the kidney against streptozotocin-induced diabetes through anti-inflammatory and anti-oxidant mechanisms. Pharmacol Res. 2014;85:45-54 pubmed publisher

Makuch E, Kuropatwa M, Kurowska E, Ciekot J, Klopotowska D, Matuszyk J. Phosphodiesterase 2 negatively regulates adenosine-induced transcription of the tyrosine hydroxylase gene in PC12 rat pheochromocytoma cells. Mol Cell Endocrinol. 2014;392:51-9 pubmed publisher

Zhou J, Riquelme M, Gao X, Ellies L, Sun L, Jiang J. Differential impact of adenosine nucleotides released by osteocytes on breast cancer growth and bone metastasis. Oncogene. 2015;34:1831-42 pubmed publisher

Dambrot C, Buermans H, Varga E, Kosmidis G, Langenberg K, Casini S, et al. Strategies for rapidly mapping proviral integration sites and assessing cardiogenic potential of nascent human induced pluripotent stem cell clones. Exp Cell Res. 2014;327:297-306 pubmed publisher

Mishima E, Inoue C, Saigusa D, Inoue R, Ito K, Suzuki Y, et al. Conformational change in transfer RNA is an early indicator of acute cellular damage. J Am Soc Nephrol. 2014;25:2316-26 pubmed publisher

Ma L, Lu N, Wu G. Antiplatelet aggregation and endothelial protection of I4, a new synthetic anti-diabetes sulfonylurea compound. Platelets. 2015;26:342-8 pubmed publisher

Brunschweiger A, Koch P, Schlenk M, Pineda F, Küppers P, Hinz S, et al. 8-Benzyltetrahydropyrazino[2,1-f]purinediones: water-soluble tricyclic xanthine derivatives as multitarget drugs for neurodegenerative diseases. ChemMedChem. 2014;9:1704-24 pubmed publisher

Jackson E, Gillespie D, Mi Z, Cheng D, Bansal R, Janesko Feldman K, et al. Role of 2',3'-cyclic nucleotide 3'-phosphodiesterase in the renal 2',3'-cAMP-adenosine pathway. Am J Physiol Renal Physiol. 2014;307:F14-24 pubmed publisher

Cui G, Qi Z, Zhang Y, Long X, Qin J, Guo X. Induction of dedifferentiated male mouse adipose stromal vascular fraction cells to primordial germ cell-like cells. Cell Biol Int. 2014;38:1069-75 pubmed publisher

Gebremeskel S, LeVatte T, Liwski R, Johnston B, Bezuhly M. The reversible P2Y12 inhibitor ticagrelor inhibits metastasis and improves survival in mouse models of cancer. Int J Cancer. 2015;136:234-40 pubmed publisher

Nescerecka A, Rubulis J, Vital M, Juhna T, Hammes F. Biological instability in a chlorinated drinking water distribution network. PLoS ONE. 2014;9:e96354 pubmed publisher

Hopmans E, Natsoulis G, Bell J, Grimes S, Sieh W, Ji H. A programmable method for massively parallel targeted sequencing. Nucleic Acids Res. 2014;42:e88 pubmed publisher

Park L, Koizumi K, El Jamal S, Zhou P, Previti M, Van Nostrand W, et al. Age-dependent neurovascular dysfunction and damage in a mouse model of cerebral amyloid angiopathy. Stroke. 2014;45:1815-21 pubmed publisher

Pey A, Majtan T, Kraus J. The role of surface electrostatics on the stability, function and regulation of human cystathionine β-synthase, a complex multidomain and oligomeric protein. Biochim Biophys Acta. 2014;1844:1453-62 pubmed publisher

Wang S, Chen P, Xu Y, Li X, Fan X. Characterization of the chemical constituents in Da-Huang-Gan-Cao-Tang by liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry and liquid chromatography coupled with ion trap mass spectrometry. J Sep Sci. 2014;37:1748-61 pubmed publisher

Liu N, Pan T. RNA epigenetics. Transl Res. 2015;165:28-35 pubmed publisher

Stoddart L, Kellam B, Briddon S, Hill S. Effect of a toggle switch mutation in TM6 of the human adenosine A? receptor on Gi protein-dependent signalling and Gi-independent receptor internalization. Br J Pharmacol. 2014;171:3827-44 pubmed publisher

Alarcon M, Fuentes E, Olate N, Navarrete S, Carrasco G, Palomo I. Strawberry extract presents antiplatelet activity by inhibition of inflammatory mediator of atherosclerosis (sP-selectin, sCD40L, RANTES, and IL-1β) and thrombus formation. Platelets. 2015;26:224-9 pubmed publisher

Yumul R, Tang R, Cokic I, Klein M, Kali A, Sobczyk O, et al. Assessment of myocardial reactivity to controlled hypercapnia with free-breathing T2-prepared cardiac blood oxygen level-dependent MR imaging. Radiology. 2014;272:397-406 pubmed publisher

Ito Y, Correll K, Schiel J, Finigan J, Prekeris R, Mason R. Lung fibroblasts accelerate wound closure in human alveolar epithelial cells through hepatocyte growth factor/c-Met signaling. Am J Physiol Lung Cell Mol Physiol. 2014;307:L94-105 pubmed publisher

Herfindal L, Krakstad C, Myhren L, Hagland H, Kopperud R, Teigen K, et al. Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3. PLoS ONE. 2014;9:e94926 pubmed publisher

Sánchez Ruiloba L, Aicart Ramos C, Garcia Guerra L, Pose Utrilla J, Rodríguez Crespo I, Iglesias T. Protein kinase D interacts with neuronal nitric oxide synthase and phosphorylates the activatory residue serine 1412. PLoS ONE. 2014;9:e95191 pubmed publisher

Niccoli G, Falcioni E, Cosentino N, Fracassi F, Roberto M, Fabretti A, et al. Impact of accuracy of fractional flow reserve to reduction of microvascular resistance after intracoronary adenosine in patients with angina pectoris or non-ST-segment elevation myocardial infarction. Am J Cardiol. 2014;113:1461-7 pubmed publisher

Bray N. Antiviral drugs: Spanner in the works of filovirus infection. Nat Rev Drug Discov. 2014;13:334 pubmed publisher

Dunkle J, Vinal K, Desai P, Zelinskaya N, Savic M, West D, et al. Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA. Proc Natl Acad Sci U S A. 2014;111:6275-80 pubmed publisher

Meyer K, Jaffrey S. The dynamic epitranscriptome: N6-methyladenosine and gene expression control. Nat Rev Mol Cell Biol. 2014;15:313-26 pubmed publisher

Wein A. Re: the regulation of ATP release from the urothelium by adenosine and transepithelial potential. J Urol. 2014;191:1054 pubmed publisher

Silva Pinto A, Dias Carlos C, Saldanha Araujo F, Ferreira F, Palma P, Araújo A, et al. Hydroxycarbamide modulates components involved in the regulation of adenosine levels in blood cells from sickle-cell anemia patients. Ann Hematol. 2014;93:1457-65 pubmed publisher

Spaans F, De Vos P, Bakker W, van Goor H, Faas M. Danger signals from ATP and adenosine in pregnancy and preeclampsia. Hypertension. 2014;63:1154-60 pubmed publisher

Schwab F, Ingrisch M, Marcus R, Bamberg F, Hildebrandt K, Adrion C, et al. Tracer kinetic modeling in myocardial perfusion quantification using MRI. Magn Reson Med. 2015;73:1206-15 pubmed publisher

Zahedifard F, Gholami E, Taheri T, Taslimi Y, Doustdari F, Seyed N, et al. Enhanced protective efficacy of nonpathogenic recombinant leishmania tarentolae expressing cysteine proteinases combined with a sand fly salivary antigen. PLoS Negl Trop Dis. 2014;8:e2751 pubmed publisher

Zhang Y, Simpson Durand C, Standifer K. Nociceptin/orphanin FQ peptide receptor antagonist JTC-801 reverses pain and anxiety symptoms in a rat model of post-traumatic stress disorder. Br J Pharmacol. 2015;172:571-82 pubmed publisher

Fu Y, Dominissini D, Rechavi G, He C. Gene expression regulation mediated through reversible m?A RNA methylation. Nat Rev Genet. 2014;15:293-306 pubmed publisher

Soares A, Costa V, Diniz C, Fresco P. Combination of Cl‑IB‑MECA with paclitaxel is a highly effective cytotoxic therapy causing mTOR‑dependent autophagy and mitotic catastrophe on human melanoma cells. J Cancer Res Clin Oncol. 2014;140:921-35 pubmed

Berman D, Stoebner R, Dey D. Combined anatomy and physiology on coronary computed tomography angiography: a step or two in the right direction. J Am Coll Cardiol. 2014;63:1913-5 pubmed publisher

Wong D, Ko B, Cameron J, Leong D, Leung M, Malaiapan Y, et al. Comparison of diagnostic accuracy of combined assessment using adenosine stress computed tomography perfusion + computed tomography angiography with transluminal attenuation gradient + computed tomography angiography against invasive fractional flow . J Am Coll Cardiol. 2014;63:1904-12 pubmed publisher

Graven P, Tambalo M, Scapozza L, Perozzo R. Purine metabolite and energy charge analysis of Trypanosoma brucei cells in different growth phases using an optimized ion-pair RP-HPLC/UV for the quantification of adenine and guanine pools. Exp Parasitol. 2014;141:28-38 pubmed publisher

Bonaca M, Bhatt D, Braunwald E, Cohen M, Steg P, Storey R, et al. Design and rationale for the Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction 54 (PEGASUS-TIMI 54) trial. Am Heart J. 2014;167:437-444.e5 pubmed publisher

Vlčková H, Ježková K, Stětková K, Tomšíková H, Solich P, Novakova L. Study of the retention behavior of small polar molecules on different types of stationary phases used in hydrophilic interaction liquid chromatography. J Sep Sci. 2014;37:1297-307 pubmed publisher

Fuentes Broto L, Albendea C, Serrano M, Rosello Catafau J, Lampreave F, López Pingarrón L, et al. Evaluation of Institut Georges Lopez-1 preservation solution in pig pancreas transplantation: a pilot study. Transplantation. 2014;97:901-7 pubmed publisher

Li J, Chu J, Barrero C, Merali S, Pratico D. Homocysteine exacerbates ?-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles. Ann Neurol. 2014;75:851-63 pubmed publisher

Kang T, Yuan J, Zhou A, Beppler C, Miller J. Deoxycytidine deaminase-deficient Escherichia coli strains display acute sensitivity to cytidine, adenosine, and guanosine and increased sensitivity to a range of antibiotics, including vancomycin. J Bacteriol. 2014;196:1950-7 pubmed publisher

Huang Z, Liu P, Zhu L, Li N, Hu H. P2X1-initiated p38 signalling enhances thromboxane A2-induced platelet secretion and aggregation. Thromb Haemost. 2014;112:142-50 pubmed publisher

Ross A, Nguyen M, Privman E, Venton B. Mechanical stimulation evokes rapid increases in extracellular adenosine concentration in the prefrontal cortex. J Neurochem. 2014;130:50-60 pubmed publisher

Dubois Colas N, Petit Jentreau L, Barreiro L, Durand S, Soubigou G, Lecointe C, et al. Extracellular adenosine triphosphate affects the response of human macrophages infected with Mycobacterium tuberculosis. J Infect Dis. 2014;210:824-33 pubmed publisher

Valletta D, Czech B, Spruss T, Ikenberg K, Wild P, Hartmann A, et al. Regulation and function of the atypical cadherin FAT1 in hepatocellular carcinoma. Carcinogenesis. 2014;35:1407-15 pubmed publisher

Warren T, Wells J, Panchal R, Stuthman K, Garza N, Van Tongeren S, et al. Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430. Nature. 2014;508:402-5 pubmed publisher

Mahaffey K, Held C, Wojdyla D, James S, Katus H, Husted S, et al. Ticagrelor effects on myocardial infarction and the impact of event adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) trial. J Am Coll Cardiol. 2014;63:1493-9 pubmed publisher

Granfeldt A, Letson H, Hyldebrandt J, Wang E, Salcedo P, Nielsen T, et al. Small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ has multiple benefits during hypotensive and blood resuscitation in the pig following severe blood loss: rat to pig translation. Crit Care Med. 2014;42:e329-44 pubmed publisher

Parsons R, Guarrera J. Preservation solutions for static cold storage of abdominal allografts: which is best?. Curr Opin Organ Transplant. 2014;19:100-7 pubmed publisher

Autio J, Shatillo A, Giniatullin R, Gröhn O. Parenchymal spin-lock fMRI signals associated with cortical spreading depression. J Cereb Blood Flow Metab. 2014;34:768-75 pubmed publisher

Yamada K, Kobayashi M, Shiozaki S, Ohta T, Mori A, Jenner P, et al. Antidepressant activity of the adenosine A2A receptor antagonist, istradefylline (KW-6002) on learned helplessness in rats. Psychopharmacology (Berl). 2014;231:2839-49 pubmed publisher

Laidlaw T, Cutler A, Kidder M, Liu T, Cardet J, Chhay H, et al. Prostaglandin E2 resistance in granulocytes from patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2014;133:1692-701.e3 pubmed publisher

Hassanian S, Dinarvand P, Rezaie A. Adenosine regulates the proinflammatory signaling function of thrombin in endothelial cells. J Cell Physiol. 2014;229:1292-300 pubmed publisher

Hirschl M. Smoking status and the effects of antiplatelet drugs. BMJ. 2013;347:f5909 pubmed publisher

Calleri E, Ubiali D, Serra I, Temporini C, Cattaneo G, Speranza G, et al. Immobilized purine nucleoside phosphorylase from Aeromonas hydrophila as an on-line enzyme reactor for biocatalytic applications. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;968:79-86 pubmed publisher

Sikora J, Markowicz Piasecka M, Broncel M, Mikiciuk Olasik E. Extract of Aronia melanocarpa-modified hemostasis: in vitro studies. Eur J Nutr. 2014;53:1493-502 pubmed publisher

Subramanian M, Kini R, Madasu M, Ohta A, Nowak M, Exley M, et al. Extracellular adenosine controls NKT-cell-dependent hepatitis induction. Eur J Immunol. 2014;44:1119-29 pubmed publisher

Schafer A, Arntz H, Boudriot E, Garlichs C, Hoffmann S, Ince H, et al. [Differentiated antiplatelet therapy for acute coronary syndromes]. Dtsch Med Wochenschr. 2014;139:152-8 pubmed publisher

Alexopoulos D, Xanthopoulou I, Stavrou K, Hahalis G, Davlouros P. Platelet reactivity measurements reveal patient noncompliance during ticagrelor maintenance therapy. Can J Cardiol. 2013;29:1743.e13-4 pubmed publisher

Gao X, Lu Q, Chou G, Wang Z, Pan R, Xia Y, et al. Norisoboldine attenuates inflammatory pain via the adenosine A1 receptor. Eur J Pain. 2014;18:939-48 pubmed publisher

Samsel M, Dzierzbicka K, Trzonkowski P. [Adenosine, its analogues and conjugates]. Postepy Hig Med Dosw (Online). 2013;67:1189-203 pubmed

Tsang K, Hartmark Hill J. Ticagrelor (Brilinta) for secondary prevention of thrombotic events following acute coronary syndrome. Am Fam Physician. 2013;88:821-2 pubmed

Baumann K. RNA: The (methylation) reader. Nat Rev Mol Cell Biol. 2014;15:2 pubmed publisher

Lu D, Insel P. Cellular mechanisms of tissue fibrosis. 6. Purinergic signaling and response in fibroblasts and tissue fibrosis. Am J Physiol Cell Physiol. 2014;306:C779-88 pubmed publisher

Ståhle M, Honkanen Scott M, Ingvast S, Korsgren O, Friberg A. Human islet isolation processing times shortened by one hour: minimized incubation time between tissue harvest and islet purification. Transplantation. 2013;96:e91-3 pubmed publisher

Angiolillo D, Curzen N, Gurbel P, Vaitkus P, Lipkin F, Li W, et al. Pharmacodynamic evaluation of switching from ticagrelor to prasugrel in patients with stable coronary artery disease: Results of the SWAP-2 Study (Switching Anti Platelet-2). J Am Coll Cardiol. 2014;63:1500-9 pubmed publisher

Alexopoulos D, Xanthopoulou I, Deftereos S, Sitafidis G, Kanakakis I, Hamilos M, et al. In-hospital switching of oral P2Y12 inhibitor treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention: prevalence, predictors and short-term outcome. Am Heart J. 2014;167:68-76.e2 pubmed publisher

Andersson O. Role of adenosine signalling and metabolism in β-cell regeneration. Exp Cell Res. 2014;321:3-10 pubmed publisher

Tani T, Nagaoka T, Nakabayashi S, Yoshioka T, Yoshida A. Autoregulation of retinal blood flow in response to decreased ocular perfusion pressure in cats: comparison of the effects of increased intraocular pressure and systemic hypotension. Invest Ophthalmol Vis Sci. 2014;55:360-7 pubmed publisher

Bakhsheshian J, Wei B, Chang K, Shukla S, Ambudkar S, Simpson R, et al. Bioluminescent imaging of drug efflux at the blood-brain barrier mediated by the transporter ABCG2. Proc Natl Acad Sci U S A. 2013;110:20801-6 pubmed publisher

Wang X, Lu Z, Gomez A, Hon G, Yue Y, Han D, et al. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014;505:117-20 pubmed publisher

. ECG response: November 26, 2013. Circulation. 2013;128:2419 pubmed publisher

Schwartz S, Agarwala S, Mumbach M, Jovanovic M, Mertins P, Shishkin A, et al. High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis. Cell. 2013;155:1409-21 pubmed publisher

Heer T, Reiter S, Höfling B, Pilz G. Diagnostic performance of non-contrast-enhanced whole-heart magnetic resonance coronary angiography in combination with adenosine stress perfusion cardiac magnetic resonance imaging. Am Heart J. 2013;166:999-1009 pubmed publisher

Peh G, Chng Z, Ang H, Cheng T, Adnan K, Seah X, et al. Propagation of human corneal endothelial cells: a novel dual media approach. Cell Transplant. 2015;24:287-304 pubmed publisher

Matos M, Augusto E, Agostinho P, Cunha R, Chen J. Antagonistic interaction between adenosine A2A receptors and Na+/K+-ATPase-?2 controlling glutamate uptake in astrocytes. J Neurosci. 2013;33:18492-502 pubmed publisher

Cheung J, Lin F, Ip J, Bender S, Siddiqi F, Liu C, et al. Adenosine-induced pulmonary vein ectopy as a predictor of recurrent atrial fibrillation after pulmonary vein isolation. Circ Arrhythm Electrophysiol. 2013;6:1066-73 pubmed publisher

Niccoli G, Spaziani C, Crea F. Left ventricular remodeling and 1-year clinical follow-up of the REOPEN-AMI trial. J Am Coll Cardiol. 2014;63:1454-5 pubmed publisher

Leavy O. T cells: adenosine maintains the numbers. Nat Rev Immunol. 2013;13:848-9 pubmed publisher

Sarvestani S, Tate M, Moffat J, Jacobi A, Behlke M, Miller A, et al. Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8. J Virol. 2014;88:799-810 pubmed publisher

Chimote A, Hajdu P, Kucher V, Boiko N, Kuras Z, Szilágyi O, et al. Selective inhibition of KCa3.1 channels mediates adenosine regulation of the motility of human T cells. J Immunol. 2013;191:6273-80 pubmed publisher

Tanaka R, Donovan N, Yu Q, Irie R, Hoon D. Tumor necrosis factor-α and apoptosis induction in melanoma cells through histone modification by 3-deazaneplanocin A. J Invest Dermatol. 2014;134:1470-1473 pubmed publisher

Antonioli L, Blandizzi C, Pacher P, Hasko G. Immunity, inflammation and cancer: a leading role for adenosine. Nat Rev Cancer. 2013;13:842-57 pubmed publisher

Yoshida T, Yamashita M, Horimai C, Hayashi M. High glucose concentration does not modulate the formation of arterial medial calcification in experimental uremic rats. J Vasc Res. 2013;50:512-20 pubmed publisher

Whiteside T. Regulatory T cell subsets in human cancer: are they regulating for or against tumor progression?. Cancer Immunol Immunother. 2014;63:67-72 pubmed publisher

Cohen D. US lawyers investigate trial that secured license for AstraZeneca's antiplatelet drug. BMJ. 2013;347:f6727 pubmed publisher

Wang S, Reid B, Dugan S, Roggenbuck J, Read L, Aref P, et al. FAM20A mutations associated with enamel renal syndrome. J Dent Res. 2014;93:42-8 pubmed publisher

Li J, Church G. Deciphering the functions and regulation of brain-enriched A-to-I RNA editing. Nat Neurosci. 2013;16:1518-22 pubmed publisher

Pardo F, Arroyo P, Salomon C, Westermeier F, Salsoso R, Saez T, et al. Role of equilibrative adenosine transporters and adenosine receptors as modulators of the human placental endothelium in gestational diabetes mellitus. Placenta. 2013;34:1121-7 pubmed publisher

Vethe N, Ali A, Reine P, Andersen A, Bremer S, Line P, et al. Simultaneous quantification of IMPDH activity and purine bases in lymphocytes using LC-MS/MS: assessment of biomarker responses to mycophenolic acid. Ther Drug Monit. 2014;36:108-18 pubmed publisher

Boison D. Role of adenosine in status epilepticus: a potential new target?. Epilepsia. 2013;54 Suppl 6:20-2 pubmed publisher

Zimmerman M, Kam I, Eltzschig H, Grenz A. Biological implications of extracellular adenosine in hepatic ischemia and reperfusion injury. Am J Transplant. 2013;13:2524-9 pubmed publisher

Nam H, Bruner R, Choi D. Adenosine signaling in striatal circuits and alcohol use disorders. Mol Cells. 2013;36:195-202 pubmed publisher

Hirota T, Kishi T. Adenosine hypothesis in schizophrenia and bipolar disorder: a systematic review and meta-analysis of randomized controlled trial of adjuvant purinergic modulators. Schizophr Res. 2013;149:88-95 pubmed publisher

Montinaro A, Iannone R, Pinto A, Morello S. Adenosine receptors as potential targets in melanoma. Pharmacol Res. 2013;76:34-40 pubmed publisher

Mikhailov V, Potapov V, Amirkhanov R, Amirkhanov N, Bulanenkova S, Akopov S, et al. [Affinity capture of specific DNA fragments with the use of short synthetic sequences]. Bioorg Khim. 2013;39:81-6 pubmed

Augusto E, Matos M, Sevigny J, El Tayeb A, Bynoe M, Muller C, et al. Ecto-5'-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions. J Neurosci. 2013;33:11390-9 pubmed publisher

Cecati M, Emanuelli M, Giannubilo S, Quarona V, Senetta R, Malavasi F, et al. Contribution of adenosine-producing ectoenzymes to the mechanisms underlying the mitigation of maternal-fetal conflicts. J Biol Regul Homeost Agents. 2013;27:519-29 pubmed

Levin L, Wallentin L, Bernfort L, Andersson D, Storey R, Bergström G, et al. Health-related quality of life of ticagrelor versus clopidogrel in patients with acute coronary syndromes-results from the PLATO trial. Value Health. 2013;16:574-80 pubmed publisher

Armstrong P, Westerhout C, Fu Y, Harrington R, Storey R, Katus H, et al. Quantitative ST-depression in acute coronary syndromes: the PLATO electrocardiographic substudy. Am J Med. 2013;126:723-729.e1 pubmed publisher

Ip J, Cheung J, Chung J, Liu C, Thomas G, Markowitz S, et al. Adenosine-induced atrial fibrillation: insights into mechanism. Circ Arrhythm Electrophysiol. 2013;6:e34-7 pubmed publisher

Elsherbiny N, Ahmad S, Naime M, Elsherbini A, Fulzele S, Al Gayyar M, et al. ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy. Life Sci. 2013;93:78-88 pubmed publisher

Headrick J, Ashton K, Rose Meyer R, Peart J. Cardiovascular adenosine receptors: expression, actions and interactions. Pharmacol Ther. 2013;140:92-111 pubmed publisher

Fioravanti A, Fumeaux C, Mohapatra S, Bompard C, Brilli M, Frandi A, et al. DNA binding of the cell cycle transcriptional regulator GcrA depends on N6-adenosine methylation in Caulobacter crescentus and other Alphaproteobacteria. PLoS Genet. 2013;9:e1003541 pubmed publisher

Aung Naing K, Li L, Su Q, Wu T. Adenosine and verapamil for no-reflow during primary percutaneous coronary intervention in people with acute myocardial infarction. Cochrane Database Syst Rev. 2013;:CD009503 pubmed publisher

Topuzogullari M, Cakir Koç R, Dincer Isoglu S, Bagirova M, Akdeste Z, Elçıçek S, et al. Conjugation, characterization and toxicity of lipophosphoglycan-polyacrylic acid conjugate for vaccination against leishmaniasis. J Biomed Sci. 2013;20:35 pubmed publisher

Rassaf T, Albert A. [Coronary heart disease: news about stents and bypasses]. Dtsch Med Wochenschr. 2013;138:1225-8 pubmed publisher

Ray S, Duval N, Wilkinson T, Shaheen S, Ghosh K, Patterson D. Inherent properties of adenylosuccinate lyase could explain S-Ado/SAICAr ratio due to homozygous R426H and R303C mutations. Biochim Biophys Acta. 2013;1834:1545-53 pubmed publisher

Belchikov Y, Koenig S, Dipasquale E. Potential role of endogenous adenosine in ticagrelor-induced dyspnea. Pharmacotherapy. 2013;33:882-7 pubmed publisher

Elsherbiny N, Naime M, Ahmad S, Elsherbini A, Mohammad S, Fulzele S, et al. Potential roles of adenosine deaminase-2 in diabetic retinopathy. Biochem Biophys Res Commun. 2013;436:355-61 pubmed publisher

Birrell J, Hirst J. Investigation of NADH binding, hydride transfer, and NAD(+) dissociation during NADH oxidation by mitochondrial complex I using modified nicotinamide nucleotides. Biochemistry. 2013;52:4048-55 pubmed publisher

Jakobsen Ø, Steensrud T. Reply to the editor. J Thorac Cardiovasc Surg. 2013;145:1685-6 pubmed publisher

Vinten Johansen J, Dobson G. Adenosine-procaine cardioplegia and adenosine-lidocaine cardioplegia: Two sides of the same coin?. J Thorac Cardiovasc Surg. 2013;145:1684-5 pubmed publisher

Saze Z, Schuler P, Hong C, Cheng D, Jackson E, Whiteside T. Adenosine production by human B cells and B cell-mediated suppression of activated T cells. Blood. 2013;122:9-18 pubmed publisher

Lu D, Insel P. Hydrolysis of extracellular ATP by ectonucleoside triphosphate diphosphohydrolase (ENTPD) establishes the set point for fibrotic activity of cardiac fibroblasts. J Biol Chem. 2013;288:19040-9 pubmed publisher

Göddertz R. [Interview with the Daiichi-Sankyo managing director Ralf Göddertz (interview by Dirk Einecke and Cornelius Heyer)]. MMW Fortschr Med. 2013;155:16 pubmed

Yokobori S, Kitamura A, Grosjean H, Bessho Y. Life without tRNAArg-adenosine deaminase TadA: evolutionary consequences of decoding the four CGN codons as arginine in Mycoplasmas and other Mollicutes. Nucleic Acids Res. 2013;41:6531-43 pubmed publisher

Muller T. Suitability of the adenosine antagonist istradefylline for the treatment of Parkinson's disease: pharmacokinetic and clinical considerations. Expert Opin Drug Metab Toxicol. 2013;9:1015-24 pubmed publisher

Caruso M, Alamo A, Crisafulli E, Raciti C, Fisichella A, Polosa R. Adenosine signaling pathways as potential therapeutic targets in respiratory disease. Expert Opin Ther Targets. 2013;17:761-72 pubmed publisher

Wiseman S, Shimizu Y, Palfrey C, Nairn A. Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCF?TRCP ubiquitin E3 ligase. J Biol Chem. 2013;288:17803-11 pubmed publisher

Florence N, Nicolas M, Raphael C, Hubert D, Etienne D, Pierre K, et al. In vivo and in vitro anti-natriuretic activity of twigs fraction from Dorstenia picta: a possible mechanism. Pak J Pharm Sci. 2013;26:537-45 pubmed

Elsherbiny N, Al Gayyar M. Adenosine receptors: new therapeutic targets for inflammation in diabetic nephropathy. Inflamm Allergy Drug Targets. 2013;12:153-61 pubmed

Wan L, Mao D, Neculai D, Strecker J, Chiovitti D, Kurinov I, et al. Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system. Nucleic Acids Res. 2013;41:6332-46 pubmed publisher

Hussain M, Javeed A, Ashraf M, Yuzhu H, Mukhtar M. Multilevel pharmacological manipulation of adenosine-prostaglandin E₂/cAMP nexus in the tumor microenvironment: a 'two hit' therapeutic opportunity. Pharmacol Res. 2013;73:8-19 pubmed publisher

Xu J, Lan D, Yang G, Li T, Liu L. Hemorrhagic preconditioning improves vascular reactivity after hemorrhagic shock by activation of PKCα and PKCε via the adenosine A1 receptor in rats. J Trauma Acute Care Surg. 2013;74:1266-74 pubmed publisher

Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, et al. Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension. Circ Res. 2013;112:1466-78 pubmed publisher

Macwar R, Williams B, Shirani J. Prognostic value of adenosine cardiac magnetic resonance imaging in patients presenting with chest pain. Am J Cardiol. 2013;112:46-50 pubmed publisher

Muroi Y, Ru F, Chou Y, Carr M, Undem B, Canning B. Selective inhibition of vagal afferent nerve pathways regulating cough using Nav 1.7 shRNA silencing in guinea pig nodose ganglia. Am J Physiol Regul Integr Comp Physiol. 2013;304:R1017-23 pubmed publisher

Grygier M, Araszkiewicz A, Lesiak M, Grajek S. Role of adenosine as an adjunct therapy in the prevention and treatment of no-reflow phenomenon in acute myocardial infarction with ST segment elevation: review of the current data. Kardiol Pol. 2013;71:115-20 pubmed publisher

Stiefelhagen P. [Your patient needs antithrombotics, 2. What do the new substances offer? (interview by Dr. med. Peter Stiefelhagen)]. MMW Fortschr Med. 2013;155:18 pubmed

James S, Pieper K, Cannon C, Storey R, Becker R, Steg P, et al. Ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials. Stroke. 2013;44:1477-9 pubmed publisher

García López J, Hourcade J, del Mazo J. Reprogramming of microRNAs by adenosine-to-inosine editing and the selective elimination of edited microRNA precursors in mouse oocytes and preimplantation embryos. Nucleic Acids Res. 2013;41:5483-93 pubmed publisher

Wengert M, Ribeiro M, Abreu T, Coutinho Silva R, Leão Ferreira L, Pinheiro A, et al. Protein kinase C-mediated ATP stimulation of Na(+)-ATPase activity in LLC-PK1 cells involves a P2Y2 and/or P2Y4 receptor. Arch Biochem Biophys. 2013;535:136-42 pubmed publisher

Fishman P, Cohen S, Bar Yehuda S. Targeting the A3 adenosine receptor for glaucoma treatment (review). Mol Med Rep. 2013;7:1723-5 pubmed publisher

Eltzschig H, Bonney S, Eckle T. Attenuating myocardial ischemia by targeting A2B adenosine receptors. Trends Mol Med. 2013;19:345-54 pubmed publisher

De Lazzari C, L Abbate A, Micalizzi M, Trivella M, Neglia D. Effects of amlodipine and adenosine on coronary haemodynamics: in vivo study and numerical simulation. Comput Methods Biomech Biomed Engin. 2014;17:1642-52 pubmed publisher

Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W. Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 2011;7:e1002310 pubmed publisher

Hassan A, Abou Elkhair R, Riordan J, Allan P, Parker W, Khare R, et al. Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides. Eur J Med Chem. 2012;47:167-74 pubmed publisher

Deflorian F, Kumar T, Phan K, Gao Z, Xu F, Wu H, et al. Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound Aâ‚‚A adenosine receptor. J Med Chem. 2012;55:538-52 pubmed publisher

Murakami E, Bao H, Mosley R, Du J, Sofia M, Furman P. Adenosine deaminase-like protein 1 (ADAL1): characterization and substrate specificity in the hydrolysis of N(6)- or O(6)-substituted purine or 2-aminopurine nucleoside monophosphates. J Med Chem. 2011;54:5902-14 pubmed publisher

Firooznia F, Cheung A, Brinkman J, Grimsby J, Gubler M, Hamid R, et al. Discovery of benzothiazole-based adenosine A2B receptor antagonists with improved A2A selectivity. Bioorg Med Chem Lett. 2011;21:1933-6 pubmed publisher

Diez Zaera M, Diaz Hernandez J, Hernández Álvarez E, Zimmermann H, Diaz Hernandez M, Miras Portugal M. Tissue-nonspecific alkaline phosphatase promotes axonal growth of hippocampal neurons. Mol Biol Cell. 2011;22:1014-24 pubmed publisher

Liu X, Yang J, Zhang S, Liu X, Liu D. Induction of cell cycle arrest at G1 and S phases and cAMP-dependent differentiation in C6 glioma by low concentration of cycloheximide. BMC Cancer. 2010;10:684 pubmed publisher

Alvarez Z, Lee K, Abel Santos E. Testing nucleoside analogues as inhibitors of Bacillus anthracis spore germination in vitro and in macrophage cell culture. Antimicrob Agents Chemother. 2010;54:5329-36 pubmed publisher

Ekins S, Williams A, Xu J. A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug Metab Dispos. 2010;38:2302-8 pubmed publisher

Greene N, Fisk L, Naven R, Note R, Patel M, Pelletier D. Developing structure-activity relationships for the prediction of hepatotoxicity. Chem Res Toxicol. 2010;23:1215-22 pubmed publisher

Cheung A, Brinkman J, Firooznia F, Flohr A, Grimsby J, Gubler M, et al. 4-Substituted-7-N-alkyl-N-acetyl 2-aminobenzothiazole amides: drug-like and non-xanthine based A2B adenosine receptor antagonists. Bioorg Med Chem Lett. 2010;20:4140-6 pubmed publisher

Furihata T, Fukuchi Y, Iikura M, Hashizume M, Miyajima A, Nagai M, et al. Striking species difference in the contribution of concentrative nucleoside transporter 2 to nucleoside uptake between mouse and rat hepatocytes. Antimicrob Agents Chemother. 2010;54:3035-8 pubmed publisher

Kruhlak N, Choi S, Contrera J, Weaver J, Willard J, Hastings K, et al. Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicol Mech Methods. 2008;18:217-27 pubmed publisher

Fourches D, Barnes J, Day N, Bradley P, Reed J, Tropsha A. Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chem Res Toxicol. 2010;23:171-83 pubmed publisher

Roy A, Lunn F, Bearne S. Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids. Bioorg Med Chem Lett. 2010;20:141-4 pubmed publisher

Luecha P, Umehara K, Miyase T, Noguchi H. Antiestrogenic constituents of the Thai medicinal plants Capparis flavicans and Vitex glabrata. J Nat Prod. 2009;72:1954-9 pubmed publisher

. Guide to Receptors and Channels (GRAC), 4th Edition. Br J Pharmacol. 2009;158 Suppl 1:S1-254 pubmed publisher

Hong J, Bhave D, Carroll K. Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5'-phosphosulfate reductase. J Med Chem. 2009;52:5485-95 pubmed publisher

Valerio D, Ferreira F, Cunha T, Alves Filho J, Lima F, De Oliveira J, et al. Fructose-1,6-bisphosphate reduces inflammatory pain-like behaviour in mice: role of adenosine acting on A1 receptors. Br J Pharmacol. 2009;158:558-68 pubmed publisher

Hernández M, Knight G, Wildman S, Burnstock G. Role of ATP and related purines in inhibitory neurotransmission to the pig urinary bladder neck. Br J Pharmacol. 2009;157:1463-73 pubmed publisher

Kasiganesan H, Wright G, Chiacchio M, Gumina G. Novel l-adenosine analogs as cardioprotective agents. Bioorg Med Chem. 2009;17:5347-52 pubmed publisher

Guo K, Li L. Differential 12C-/13C-isotope dansylation labeling and fast liquid chromatography/mass spectrometry for absolute and relative quantification of the metabolome. Anal Chem. 2009;81:3919-32 pubmed publisher

Williamson D, Borgognoni J, Clay A, Daniels Z, Dokurno P, Drysdale M, et al. Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design. J Med Chem. 2009;52:1510-3 pubmed publisher

Wei E, Hamm R, Baranova A, Povlishock J. The long-term microvascular and behavioral consequences of experimental traumatic brain injury after hypothermic intervention. J Neurotrauma. 2009;26:527-37 pubmed publisher

Girouard H, Wang G, Gallo E, Anrather J, Zhou P, Pickel V, et al. NMDA receptor activation increases free radical production through nitric oxide and NOX2. J Neurosci. 2009;29:2545-52 pubmed publisher

Sánchez Cañete M, Carvalho L, Pérez Victoria F, Gamarro F, Castanys S. Low plasma membrane expression of the miltefosine transport complex renders Leishmania braziliensis refractory to the drug. Antimicrob Agents Chemother. 2009;53:1305-13 pubmed publisher

Chen L, Petrelli R, Olesiak M, Wilson D, Labello N, Pankiewicz K. Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase. Bioorg Med Chem. 2008;16:7462-9 pubmed publisher

Kim Y, Sharon A, Chu C, Rais R, Al Safarjalani O, Naguib F, et al. Structure-activity relationships of 7-deaza-6-benzylthioinosine analogues as ligands of Toxoplasma gondii adenosine kinase. J Med Chem. 2008;51:3934-45 pubmed publisher

Jacobsson M, Gäredal M, Schultz J, Karlen A. Identification of Plasmodium falciparum spermidine synthase active site binders through structure-based virtual screening. J Med Chem. 2008;51:2777-86 pubmed publisher

Vilardaga J, Nikolaev V, Lorenz K, Ferrandon S, Zhuang Z, Lohse M. Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling. Nat Chem Biol. 2008;4:126-31 pubmed publisher

Brdar B, Reich E. Biochemical and biological properties of 5-bromotubercidin: differential effects on cellular DNA-directed and viral RNA-directed RNA synthesis. Bioorg Med Chem. 2008;16:1481-92 pubmed

Hermann J, Marti Arbona R, Fedorov A, Fedorov E, Almo S, Shoichet B, et al. Structure-based activity prediction for an enzyme of unknown function. Nature. 2007;448:775-9 pubmed publisher

Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed

Huang N, Chern Y, Fang J, Lin C, Chen W, Lin Y. Neuroprotective principles from Gastrodia elata. J Nat Prod. 2007;70:571-4 pubmed

Kaufmann I, Hoelzl A, Schliephake F, Hummel T, Chouker A, Łysenko L, et al. Effects of adenosine on functions of polymorphonuclear leukocytes from patients with septic shock. Shock. 2007;27:25-31 pubmed

Duewelhenke N, Krut O, Eysel P. Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. Antimicrob Agents Chemother. 2007;51:54-63 pubmed

Nishonov A, Ma X, Nair V. Azadideoxyadenosine: synthesis, enzymology, and anti-HIV activity. Bioorg Med Chem Lett. 2006;16:4099-101 pubmed

Gao Z, Duong H, Sonina T, Kim S, Van Rompaey P, Van Calenbergh S, et al. Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists. J Med Chem. 2006;49:2689-702 pubmed

Gheorghiade M, Teerlink J, Mebazaa A. Pharmacology of new agents for acute heart failure syndromes. Am J Cardiol. 2005;96:68G-73G pubmed

Maytin M, Colucci W. Cardioprotection: a new paradigm in the management of acute heart failure syndromes. Am J Cardiol. 2005;96:26G-31G pubmed

Skålhegg B, Funderud A, Henanger H, Hafte T, Larsen A, Kvissel A, et al. Protein kinase A (PKA)--a potential target for therapeutic intervention of dysfunctional immune cells. Curr Drug Targets. 2005;6:655-64 pubmed

Dodge Kafka K, Soughayer J, Pare G, Carlisle Michel J, Langeberg L, Kapiloff M, et al. The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature. 2005;437:574-8 pubmed

Koeris M, Funke L, Shrestha J, Rich A, Maas S. Modulation of ADAR1 editing activity by Z-RNA in vitro. Nucleic Acids Res. 2005;33:5362-70 pubmed

Wang M, Zhang J, Andrei D, Kuczera K, Borchardt R, Wnuk S. Are L-adenosine and its derivatives substrates for S-adenosyl-L-homocysteine hydrolase?. J Med Chem. 2005;48:3649-53 pubmed

Nakayama Y, Kinoshita A, Tomita M. Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition. Theor Biol Med Model. 2005;2:18 pubmed

Gilli P, Gilli G, Borea P, Varani K, Scatturin A, Dalpiaz A. Binding thermodynamics as a tool to investigate the mechanisms of drug-receptor interactions: thermodynamics of cytoplasmic steroid/nuclear receptors in comparison with membrane receptors. J Med Chem. 2005;48:2026-35 pubmed

Dunne V, Bhattachayya S, Besser M, Rae C, Griffin J. Metabolites from cerebrospinal fluid in aneurysmal subarachnoid haemorrhage correlate with vasospasm and clinical outcome: a pattern-recognition 1H NMR study. NMR Biomed. 2005;18:24-33 pubmed

Lee S, Jung B, Kim S, Chung B. A rapid and sensitive method for quantitation of nucleosides in human urine using liquid chromatography/mass spectrometry with direct urine injection. Rapid Commun Mass Spectrom. 2004;18:973-7 pubmed

Ballantyne P. Social context and outcomes for the ageing breast cancer patient: considerations for clinical practitioners. J Clin Nurs. 2004;13:11-21 pubmed

Vidotto C, Fousert D, Akkermann M, Griesmacher A, Müller M. Purine and pyrimidine metabolites in children's urine. Clin Chim Acta. 2003;335:27-32 pubmed

Galley H, Le Cras A, Yassen K, Grant I, Webster N. Circulating tetrahydrobiopterin concentrations in patients with septic shock. Br J Anaesth. 2001;86:578-80 pubmed

Jansen R, Kruijt J, van Berkel T, Meijer D. Coupling of the antiviral drug ara-AMP to lactosaminated albumin leads to specific uptake in rat and human hepatocytes. Hepatology. 1993;18:146-52 pubmed

Capogrossi M, Holdiness M, Israili Z. Determination of adenosine in normal human plasma and serum by high-performance liquid chromatography. J Chromatogr. 1982;227:168-73 pubmed

Ontyd J, Schrader J. Measurement of adenosine, inosine, and hypoxanthine in human plasma. J Chromatogr. 1984;307:404-9 pubmed

Eells J, Spector R. Purine and pyrimidine base and nucleoside concentrations in human cerebrospinal fluid and plasma. Neurochem Res. 1983;8:1451-7 pubmed