Anti-Amyloid Precursor Protein, C-Terminal antibody produced in rabbit

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MilliporeSigma

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science

product type :

antibody

product name :

Anti-Amyloid Precursor Protein, C-Terminal antibody produced in rabbit

catalog :

A8717

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

citations: 6

Reference
Su Q, Li T, He P, Lu X, Yu Q, Gao Q, et al. Trichostatin A ameliorates Alzheimer's disease-related pathology and cognitive deficits by increasing albumin expression and Aβ clearance in APP/PS1 mice. Alzheimers Res Ther. 2021;13:7 pubmed publisher
Feng W, Zhang Y, Wang Z, Xu H, Wu T, Marshall C, et al. Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer's disease mouse model with suppression of glymphatic clearance. Alzheimers Res Ther. 2020;12:125 pubmed publisher
Hu T, Zhou Y, Lu J, Xia P, Chen Y, Cao X, et al. A novel rhamnoside derivative PL402 up-regulates matrix metalloproteinase 3/9 to promote Aβ degradation and alleviates Alzheimer's-like pathology. Aging (Albany NY). 2020;12:481-501 pubmed publisher
Goldberg J, Currais A, Prior M, Fischer W, Chiruta C, RATLIFF E, et al. The mitochondrial ATP synthase is a shared drug target for aging and dementia. Aging Cell. 2018;17: pubmed publisher
Wagner L, Gilling K, Schormann E, Kloetzel P, Heppner F, Krüger E, et al. Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer's disease-like APPPS1 mice. Acta Neuropathol Commun. 2017;5:52 pubmed publisher
Chapuis J, Flaig A, Grenier Boley B, Eysert F, Pottiez V, Deloison G, et al. Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism. Acta Neuropathol. 2017;133:955-966 pubmed publisher

product information

Product No. :

A8717

Product Name :

Anti-Amyloid Precursor Protein, C-Terminal antibody produced in rabbit

Host :

rabbit

Conjugate :

unconjugated

Antibody Type :

polyclonal

Applications/Description :

Suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1000 using formic acid-treated sections of human Alzheimer′s disease (AD) brain; western blot: 1:4,000 using rat brain extract; microarray

Species Reactivity :

rat, mouse, human

Storage :

Store at -20°C