Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; loading ...; fig 5c
| O Donnell J, Phillips B, Yagita Y, Juszkiewicz S, Wagner A, Malinverni D, et al. The architecture of EMC reveals a path for membrane protein insertion. elife. 2020;9: pubmed publisher
|
- western blot; human; 1:1000; loading ...; fig 1
| Kido K, Yamanaka S, Nakano S, Motani K, Shinohara S, Nozawa A, et al. AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions. elife. 2020;9: pubmed publisher
|
- western blot; chicken; fig s3
| Romanello M, Schiavone D, Frey A, Sale J. Histone H3.3 promotes IgV gene diversification by enhancing formation of AID-accessible single-stranded DNA. EMBO J. 2016;35:1452-64 pubmed publisher
|
| Zhang Y, Liu J, Lin J, Zhou L, Song Y, Wei B, et al. The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGF-mediated angiogenesis and tumor growth and predict clinical outcome of breast cancer. Oncotarget. 2016;7:9859-75 pubmed publisher
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- immunoprecipitation; mouse; 1:3000; fig 2
| Cipressa F, Morciano P, Bosso G, Mannini L, Galati A, Raffa G, et al. A role for Separase in telomere protection. Nat Commun. 2016;7:10405 pubmed publisher
|
- western blot; human; 1:1000; fig 8
| Nelson J, Cook E, Loregger A, Hoeksema M, Scheij S, Kovacevic I, et al. Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake. J Biol Chem. 2016;291:4813-25 pubmed publisher
|
- western blot; human; fig 1
- immunoprecipitation; mouse; fig 1
| Bode D, Yu L, Tate P, Pardo M, Choudhary J. Characterization of Two Distinct Nucleosome Remodeling and Deacetylase (NuRD) Complex Assemblies in Embryonic Stem Cells. Mol Cell Proteomics. 2016;15:878-91 pubmed publisher
|
- western blot; human; 1:1000; fig 2
| Anadón C, Guil S, Simó Riudalbas L, Moutinho C, Setien F, MartÃnez Cardús A, et al. Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis. Oncogene. 2016;35:4407-13 pubmed publisher
|
- western blot; human; 1:1000; fig 2
| Xi L, Schmidt J, Zaug A, Ascarrunz D, Cech T. A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol. 2015;16:231 pubmed publisher
|
- immunocytochemistry; fission yeast; 1:100
| Rostislavleva K, Soler N, Ohashi Y, Zhang L, Pardon E, Burke J, et al. Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes. Science. 2015;350:aac7365 pubmed publisher
|
- immunoprecipitation; human; fig 1a
| Xie X, Wang M, Mei J, Hu F, Ding F, Lv L. Pyruvate kinase M2 interacts with DNA damage-binding protein 2 and reduces cell survival upon UV irradiation. Biochem Biophys Res Commun. 2015;467:427-33 pubmed publisher
|
- western blot; mouse; fig 2a
| Meyer M, Benkusky N, Onal M, Pike J. Selective regulation of Mmp13 by 1,25(OH)2D3, PTH, and Osterix through distal enhancers. J Steroid Biochem Mol Biol. 2016;164:258-264 pubmed publisher
|
- western blot; mouse; fig 5
| Preuße K, Tveriakhina L, Schuster Gossler K, Gaspar C, Rosa A, Henrique D, et al. Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo. PLoS Genet. 2015;11:e1005328 pubmed publisher
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- western blot; mouse; fig 1, 5, 6
- immunoprecipitation; human; fig 3
- western blot; human; fig 1, 5, 6
| Hwang B, McCool K, Wan J, Wuerzberger Davis S, Young E, Choi E, et al. IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation. J Biol Chem. 2015;290:17967-84 pubmed publisher
|
- western blot; human; fig 2
| Kumar S, Ingle H, Mishra S, Mahla R, Kumar A, Kawai T, et al. IPS-1 differentially induces TRAIL, BCL2, BIRC3 and PRKCE in type I interferons-dependent and -independent anticancer activity. Cell Death Dis. 2015;6:e1758 pubmed publisher
|
- western blot; human; 1:1000; fig s6
| Lelek M, Casartelli N, Pellin D, Rizzi E, Souque P, Severgnini M, et al. Chromatin organization at the nuclear pore favours HIV replication. Nat Commun. 2015;6:6483 pubmed publisher
|
- immunoprecipitation; mouse; fig 9
- western blot; mouse; 1:5000; fig 9
| Yan Y, Tsukamoto O, Nakano A, Kato H, Kioka H, Ito N, et al. Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5. Nat Commun. 2015;6:6137 pubmed publisher
|
- western blot; human; fig 6
| Howard S, Yanez D, Stark J. DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining. PLoS Genet. 2015;11:e1004943 pubmed publisher
|
- western blot; bovine; fig s10
| Marsolier J, Perichon M, Debarry J, Villoutreix B, Chluba J, Lopez T, et al. Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation. Nature. 2015;520:378-82 pubmed publisher
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| Kanazawa I, Canaff L, Abi Rafeh J, Angrula A, Li J, Riddle R, et al. Osteoblast menin regulates bone mass in vivo. J Biol Chem. 2015;290:3910-24 pubmed publisher
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| Inagaki T, Iwasaki S, Matsumura Y, Kawamura T, Tanaka T, Abe Y, et al. The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis. J Biol Chem. 2015;290:4163-77 pubmed publisher
|
- immunocytochemistry; human; 1:5000
- western blot; human; 1:1000
| Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, et al. Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem. 2015;290:1269-80 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Vulto van Silfhout A, Nakagawa T, Bahi Buisson N, Haas S, Hu H, Bienek M, et al. Variants in CUL4B are associated with cerebral malformations. Hum Mutat. 2015;36:106-17 pubmed publisher
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- western blot; mouse; 1:2,000
| Shiba Fukushima K, Inoshita T, Hattori N, Imai Y. Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy. J Biol Chem. 2014;289:33131-6 pubmed publisher
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| Nishibuchi G, Machida S, Osakabe A, Murakoshi H, Hiragami Hamada K, Nakagawa R, et al. N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity. Nucleic Acids Res. 2014;42:12498-511 pubmed publisher
|
- immunoprecipitation; human; fig 5
| Tsuchiya M, Yamaguchi F, Shimamoto S, Fujimoto T, Tokumitsu H, Tokuda M, et al. Oxidized S100A4 inhibits the activation of protein phosphatase 5 through S100A1 in MKN‑45 gastric carcinoma cells. Int J Mol Med. 2014;34:1713-9 pubmed publisher
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- immunoprecipitation; human
- immunocytochemistry; human
- western blot; human
- immunoprecipitation; mouse
- immunocytochemistry; mouse
- western blot; mouse
| Ro S, Semple I, Park H, Park H, Park H, Kim M, et al. Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1. FEBS J. 2014;281:3816-27 pubmed publisher
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- immunoprecipitation; human
| Zhang P, Gao K, Tang Y, Jin X, An J, Yu H, et al. Destruction of DDIT3/CHOP protein by wild-type SPOP but not prostate cancer-associated mutants. Hum Mutat. 2014;35:1142-51 pubmed publisher
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| Chang P, Hung C, Wang S, Tsai P, Shih Y, Chen L, et al. Identification and characterization of two novel spliced genes located in the orf47-orf46-orf45 gene locus of Kaposi's sarcoma-associated herpesvirus. J Virol. 2014;88:10092-109 pubmed publisher
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| Sankar S, Theisen E, Bearss J, Mulvihill T, Hoffman L, Sorna V, et al. Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth. Clin Cancer Res. 2014;20:4584-97 pubmed publisher
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- immunoprecipitation; human
- western blot; human
| Choi Y, Kim Y, Jeong H, Jin Y, Yeo C, Lee K. Akt enhances Runx2 protein stability by regulating Smurf2 function during osteoblast differentiation. FEBS J. 2014;281:3656-66 pubmed publisher
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| Munoz M, Yanez D, Stark J. An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells. Nucleic Acids Res. 2014;42:7720-33 pubmed publisher
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- immunocytochemistry; human; 1:500
- western blot; human; 1:1000-30000
| Hans F, Fiesel F, Strong J, J ckel S, Rasse T, Geisler S, et al. UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination. J Biol Chem. 2014;289:19164-79 pubmed publisher
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- immunoprecipitation; human
- immunocytochemistry; human
- western blot; human
| Shaw Hallgren G, Chmielarska Masoumi K, Zarrizi R, Hellman U, Karlsson P, Helou K, et al. Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells. PLoS ONE. 2014;9:e96506 pubmed publisher
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- immunocytochemistry; human
| Vidi P, Liu J, Salles D, Jayaraman S, Dorfman G, Gray M, et al. NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaks. Nucleic Acids Res. 2014;42:6365-79 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Cipriano R, Miskimen K, Bryson B, Foy C, Bartel C, Jackson M. Conserved oncogenic behavior of the FAM83 family regulates MAPK signaling in human cancer. Mol Cancer Res. 2014;12:1156-65 pubmed publisher
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- immunocytochemistry; human
| Kerdivel G, Boudot A, Habauzit D, Percevault F, Demay F, Pakdel F, et al. Activation of the MKL1/actin signaling pathway induces hormonal escape in estrogen-responsive breast cancer cell lines. Mol Cell Endocrinol. 2014;390:34-44 pubmed publisher
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| Havel J, Li Z, Cheng D, Peng J, Fu H. Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway. Oncogene. 2015;34:1487-98 pubmed publisher
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- immunocytochemistry; human
| Salvi M, Raiborg C, Hanson P, Campsteijn C, Stenmark H, Pinna L. CK2 involvement in ESCRT-III complex phosphorylation. Arch Biochem Biophys. 2014;545:83-91 pubmed publisher
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- immunoprecipitation; human
- western blot; human
| Zhang W, Ji W, Liu X, Ouyang G, Xiao W. ELL inhibits E2F1 transcriptional activity by enhancing E2F1 deacetylation via recruitment of histone deacetylase 1. Mol Cell Biol. 2014;34:765-75 pubmed publisher
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- immunocytochemistry; African green monkey
- western blot; mouse
| Brot S, Auger C, Bentata R, Rogemond V, Ménigoz S, Chounlamountri N, et al. Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites. J Biol Chem. 2014;289:2261-76 pubmed publisher
|
- immunohistochemistry - frozen section; Xenopus laevis
| Chu C, Gerstenzang E, Ossipova O, Sokol S. Lulu regulates Shroom-induced apical constriction during neural tube closure. PLoS ONE. 2013;8:e81854 pubmed publisher
|
- immunoprecipitation; human
- immunocytochemistry; human
- western blot; human; fig 2
| Liu X, Xiao W, Wang X, Li Y, Han J, Li Y. The p38-interacting protein (p38IP) regulates G2/M progression by promoting ?-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5. J Biol Chem. 2013;288:36648-61 pubmed publisher
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- western blot; mouse; 1:2000
| Evans C, Cook S, Coleman M, Gilley J. MEK inhibitor U0126 reverses protection of axons from Wallerian degeneration independently of MEK-ERK signaling. PLoS ONE. 2013;8:e76505 pubmed publisher
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- immunocytochemistry; human; fig 2b
| Hashizume C, Kobayashi A, Wong R. Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe. Cell Death Dis. 2013;4:e854 pubmed publisher
|
- western blot; fission yeast
| DeGennaro C, Alver B, Marguerat S, Stepanova E, Davis C, Bähler J, et al. Spt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast. Mol Cell Biol. 2013;33:4779-92 pubmed publisher
|
- immunoprecipitation; human
- immunoprecipitation; mouse
| Ravnskjaer K, Hogan M, Lackey D, Tora L, Dent S, Olefsky J, et al. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. J Clin Invest. 2013;123:4318-28 pubmed publisher
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- immunocytochemistry; human
- western blot; human
| Berndt A, Wilkinson K, Heimann M, Bishop P, Henley J. In vivo characterization of the properties of SUMO1-specific monobodies. Biochem J. 2013;456:385-95 pubmed publisher
|
- immunoprecipitation; human
- western blot; human; fig 3
| Verma S, Cai Q, Kreider E, Lu J, Robertson E. Comprehensive analysis of LANA interacting proteins essential for viral genome tethering and persistence. PLoS ONE. 2013;8:e74662 pubmed publisher
|
- immunoprecipitation; human
| Shats I, Gatza M, Liu B, Angus S, You L, Nevins J. FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function. Cancer Res. 2013;73:6056-67 pubmed publisher
|
- immunocytochemistry; mouse; 1:1000
- immunocytochemistry; human; 1:1000
| Wang C, Low W, Liu A, Wang B. Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis. J Biol Chem. 2013;288:29518-29 pubmed publisher
|
| Sy S, Jiang J, O W, Deng Y, Huen M. The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks. Nucleic Acids Res. 2013;41:8572-80 pubmed publisher
|
- western blot; mouse; 1:25,000
| Evans P, Lee S, Smith Y, Hepler J. Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain. J Comp Neurol. 2014;522:186-203 pubmed publisher
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- immunoprecipitation; human
| Wei Q, Li J, Liu T, Tong X, Ye X. Phosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulation. J Biol Chem. 2013;288:19715-25 pubmed publisher
|
| Boehlke C, Kotsis F, Buchholz B, Powelske C, Eckardt K, Walz G, et al. Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells. PLoS ONE. 2013;8:e62165 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Kubota S, Fukumoto Y, Aoyama K, Ishibashi K, Yuki R, Morinaga T, et al. Phosphorylation of KRAB-associated protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by nuclear tyrosine kinases inhibits the association of KAP1 and heterochromatin protein 1? (HP1?) with heterochromatin. J Biol Chem. 2013;288:17871-83 pubmed publisher
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| Yasuda Inoue M, Kuroki M, Ariumi Y. Distinct DDX DEAD-box RNA helicases cooperate to modulate the HIV-1 Rev function. Biochem Biophys Res Commun. 2013;434:803-8 pubmed publisher
|
- western blot; human; fig 4
| Tinnikov A, Samuels H. A novel cell lysis approach reveals that caspase-2 rapidly translocates from the nucleus to the cytoplasm in response to apoptotic stimuli. PLoS ONE. 2013;8:e61085 pubmed publisher
|
| Gal J, Chen J, Barnett K, Yang L, Brumley E, Zhu H. HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylation. J Biol Chem. 2013;288:15035-45 pubmed publisher
|
- immunoprecipitation; mouse
| Zhang J, Twelvetrees A, Lazarus J, Blasier K, Yao X, Inamdar N, et al. Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions. Cytoskeleton (Hoboken). 2013;70:215-27 pubmed publisher
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- immunocytochemistry; chicken; 1:500
| Wang Y, Dantas T, Lalor P, Dockery P, Morrison C. Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response. Cell Cycle. 2013;12:635-46 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Dettmer U, Newman A, Luth E, Bartels T, Selkoe D. In vivo cross-linking reveals principally oligomeric forms of ?-synuclein and ?-synuclein in neurons and non-neural cells. J Biol Chem. 2013;288:6371-85 pubmed publisher
|
- western blot; chicken
- immunoprecipitation; human
- western blot; human; fig s10
| Moreno Garcia M, Sommer K, Rincón Arano H, Brault M, Ninomiya Tsuji J, Matesic L, et al. Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-?B activation. Mol Cell Biol. 2013;33:1149-63 pubmed publisher
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- immunohistochemistry - frozen section; mouse
| Deguchi K, Nagamatsu G, Miyachi H, Kato Y, Morita S, Kimura H, et al. Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells. Biol Reprod. 2013;88:36 pubmed publisher
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| Morlando M, Dini Modigliani S, Torrelli G, Rosa A, Di Carlo V, Caffarelli E, et al. FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment. EMBO J. 2012;31:4502-10 pubmed publisher
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- immunocytochemistry; African green monkey; 1:2000
- western blot; African green monkey; 1:4000
| Varco Merth B, Mirza K, Alzhanov D, Chia D, Rotwein P. Biochemical characterization of diverse Stat5b-binding enhancers that mediate growth hormone-activated insulin-like growth factor-I gene transcription. PLoS ONE. 2012;7:e50278 pubmed publisher
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| Sankar S, Bell R, Stephens B, Zhuo R, Sharma S, Bearss D, et al. Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma. Oncogene. 2013;32:5089-100 pubmed publisher
|
- immunoprecipitation; human
- immunoprecipitation; mouse
| Wang C, Kao Y, Lai P, Chen W, Chung B. Steroidogenic factor 1 (NR5A1) maintains centrosome homeostasis in steroidogenic cells by restricting centrosomal DNA-dependent protein kinase activation. Mol Cell Biol. 2013;33:476-84 pubmed publisher
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| Journo C, Bonnet A, Favre Bonvin A, Turpin J, Vinera J, C t E, et al. Human T cell leukemia virus type 2 tax-mediated NF-?B activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO. J Virol. 2013;87:1123-36 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Katoh H, Okamoto T, Fukuhara T, Kambara H, Morita E, Mori Y, et al. Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation. J Virol. 2013;87:489-502 pubmed publisher
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- immunocytochemistry; mouse
| Magli A, Schnettler E, Rinaldi F, Bremer P, Perlingeiro R. Functional dissection of Pax3 in paraxial mesoderm development and myogenesis. Stem Cells. 2013;31:59-70 pubmed publisher
|
- immunoprecipitation; human
| Shia W, Okumura A, Yan M, Sarkeshik A, Lo M, Matsuura S, et al. PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential. Blood. 2012;119:4953-62 pubmed publisher
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- immunoprecipitation; human
- western blot; human
| Zhou F, Zhang X, van Dam H, Ten Dijke P, Huang H, Zhang L. Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation. J Biol Chem. 2012;287:11002-10 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Heinz L, Rebsamen M, Rossi D, Staehli F, Schroder K, Quadroni M, et al. The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade. Cell Death Differ. 2012;19:722-31 pubmed publisher
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| Lovric M, Hawkins C. TRAIL treatment provokes mutations in surviving cells. Oncogene. 2010;29:5048-60 pubmed publisher
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- immunocytochemistry; human; 1:1000
- western blot; human; 1:10000
| Roblek M, Schüchner S, Huber V, Ollram K, Vlcek Vesely S, Foisner R, et al. Monoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482W. PLoS ONE. 2010;5:e10604 pubmed publisher
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| Siatecka M, Lohmann F, Bao S, Bieker J. EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation. Mol Cell Biol. 2010;30:2811-22 pubmed publisher
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- immunoprecipitation; human
- western blot; human
| Nayak A, Glöckner Pagel J, Vaeth M, Schumann J, Buttmann M, Bopp T, et al. Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase. J Biol Chem. 2009;284:10935-46 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Zhao Y, Lang G, Ito S, Bonnet J, Metzger E, Sawatsubashi S, et al. A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. Mol Cell. 2008;29:92-101 pubmed publisher
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| Chang L, Yang J, Jo C, Boland A, Zhang Z, McLaughlin S, et al. Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state. Nat Commun. 2020;11:3464 pubmed publisher
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| Cortez J, Montauti E, Shifrut E, Gatchalian J, Zhang Y, Shaked O, et al. CRISPR screen in regulatory T cells reveals modulators of Foxp3. Nature. 2020;582:416-420 pubmed publisher
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| Krishnan A, Berthelet J, Renaud E, Rosigkeit S, Distler U, Stawiski E, et al. Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas. Nat Commun. 2020;11:2056 pubmed publisher
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| Kuhn A, Ramans Harborough S, McLaughlin H, Natarajan B, Verstraeten I, Friml J, et al. Direct ETTIN-auxin interaction controls chromatin states in gynoecium development. elife. 2020;9: pubmed publisher
|
| Hong A, Meng Z, Plouffe S, Lin Z, Zhang M, Guan K. Critical roles of phosphoinositides and NF2 in Hippo pathway regulation. Genes Dev. 2020;34:511-525 pubmed publisher
|
| Kosciuk T, Price I, Zhang X, Zhu C, Johnson K, Zhang S, et al. NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle. Nat Commun. 2020;11:1067 pubmed publisher
|
| Letko M, Marzi A, Munster V. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nat Microbiol. 2020;: pubmed publisher
|
| Yang F, Huang X, Zang R, Chen J, Fidalgo M, Sanchez Priego C, et al. DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State. Cell Stem Cell. 2020;26:234-250.e7 pubmed publisher
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| Zhang X, Guo W, Du D, Pu L, Zhang C. Overexpression of a maize BR transcription factor ZmBZR1 in Arabidopsis enlarges organ and seed size of the transgenic plants. Plant Sci. 2020;292:110378 pubmed publisher
|
| An H, Fan C, Sharif M, Kim D, Poitelon Y, Park Y. Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects. Sci Rep. 2020;10:814 pubmed publisher
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| Qiu M, Li Y, Zhang X, Xuan M, Zhang B, Ye W, et al. G protein α subunit suppresses sporangium formation through a serine/threonine protein kinase in Phytophthora sojae. PLoS Pathog. 2020;16:e1008138 pubmed publisher
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| Jiang M, Kang Y, Sewastianik T, Wang J, Tanton H, Alder K, et al. BCL9 provides multi-cellular communication properties in colorectal cancer by interacting with paraspeckle proteins. Nat Commun. 2020;11:19 pubmed publisher
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| Ninova M, Godneeva B, Chen Y, Luo Y, Prakash S, Jankovics F, et al. The SUMO Ligase Su(var)2-10 Controls Hetero- and Euchromatic Gene Expression via Establishing H3K9 Trimethylation and Negative Feedback Regulation. Mol Cell. 2020;77:571-585.e4 pubmed publisher
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| Kim K, Kim J, Kim I, Seong S, Kim N. Rev-erbα Negatively Regulates Osteoclast and Osteoblast Differentiation through p38 MAPK Signaling Pathway. Mol Cells. 2020;43:34-47 pubmed publisher
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| Miyake N, Takahashi H, Nakamura K, Isidor B, Hiraki Y, Koshimizu E, et al. Gain-of-Function MN1 Truncation Variants Cause a Recognizable Syndrome with Craniofacial and Brain Abnormalities. Am J Hum Genet. 2020;106:13-25 pubmed publisher
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| Bhatta A, Atianand M, Jiang Z, Crabtree J, Blin J, Fitzgerald K. A Mitochondrial Micropeptide Is Required for Activation of the Nlrp3 Inflammasome. J Immunol. 2020;204:428-437 pubmed publisher
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| Fujimitsu K, Yamano H. PP2A-B56 binds to Apc1 and promotes Cdc20 association with the APC/C ubiquitin ligase in mitosis. EMBO Rep. 2020;21:e48503 pubmed publisher
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| Ilik I, Aktas T, Maticzka D, Backofen R, Akhtar A. FLASH: ultra-fast protocol to identify RNA-protein interactions in cells. Nucleic Acids Res. 2020;48:e15 pubmed publisher
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| Cao G, Gao X, Zhan Y, Wang Q, Zhang Z, Dimitrov D, et al. An engineered human IgG1 CH2 domain with decreased aggregation and nonspecific binding. MAbs. 2020;12:1689027 pubmed publisher
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| Iglesias N, Paulo J, Tatarakis A, Wang X, Edwards A, Bhanu N, et al. Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance. Mol Cell. 2020;77:51-66.e8 pubmed publisher
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| Liao K, Peng Y, Yuan L, Dai Y, Chen Q, Yu L, et al. Brassinosteroids Antagonize Jasmonate-Activated Plant Defense Responses through BRI1-EMS-SUPPRESSOR1 (BES1). Plant Physiol. 2020;182:1066-1082 pubmed publisher
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| Qi H, Li J, Xia F, Chen J, Lei X, Han M, et al. Arabidopsis SINAT Proteins Control Autophagy by Mediating Ubiquitylation and Degradation of ATG13. Plant Cell. 2020;32:263-284 pubmed publisher
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| Lin Z, Gasic I, Chandrasekaran V, Peters N, Shao S, Mitchison T, et al. TTC5 mediates autoregulation of tubulin via mRNA degradation. Science. 2020;367:100-104 pubmed publisher
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| Yang W, Lin T, Chang L, Yeh W, Huang S, Chen T, et al. HIV-1 Tat Interacts with a Kaposi's Sarcoma-Associated Herpesvirus Reactivation-Upregulated Antiangiogenic Long Noncoding RNA, LINC00313, and Antagonizes Its Function. J Virol. 2020;94: pubmed publisher
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| Natarajan N, Foresti O, Wendrich K, Stein A, Carvalho P. Quality Control of Protein Complex Assembly by a Transmembrane Recognition Factor. Mol Cell. 2020;77:108-119.e9 pubmed publisher
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| Zeng X, Gao Z, Jiang C, Yang Y, Liu R, He Y. HISTONE DEACETYLASE 9 Functions with Polycomb Silencing to Repress FLOWERING LOCUS C Expression. Plant Physiol. 2020;182:555-565 pubmed publisher
|
| Morishita R, Sugiyama S, Denda M, Tokunaga S, Kido K, Shioya R, et al. CF-PA2Vtech: a cell-free human protein array technology for antibody validation against human proteins. Sci Rep. 2019;9:19349 pubmed publisher
|
| Sato Y, Tsuchiya H, Yamagata A, Okatsu K, Tanaka K, Saeki Y, et al. Structural insights into ubiquitin recognition and Ufd1 interaction of Npl4. Nat Commun. 2019;10:5708 pubmed publisher
|
| Gong B, Guo J, Zhang N, Yao X, Wang H, Li J. Cross-Microbial Protection via Priming a Conserved Immune Co-Receptor through Juxtamembrane Phosphorylation in Plants. Cell Host Microbe. 2019;26:810-822.e7 pubmed publisher
|
| Gokhale N, McIntyre A, Mattocks M, Holley C, Lazear H, Mason C, et al. Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection. Mol Cell. 2019;: pubmed publisher
|
| Lee Y, Ho S, Graves J, Xiao Y, Huang S, Lin W. CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer. Breast Cancer Res. 2019;21:134 pubmed publisher
|
| Nomura S, Takahashi H, Suzuki J, Kuwahara M, Yamashita M, Sawasaki T. Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro. Sci Rep. 2019;9:17335 pubmed publisher
|
| Codato R, Perichon M, Divol A, Fung E, Sotiropoulos A, Bigot A, et al. The SMYD3 methyltransferase promotes myogenesis by activating the myogenin regulatory network. Sci Rep. 2019;9:17298 pubmed publisher
|
| Kim M, Jeon J, Lee S, Lee J, Gao L, Lee B, et al. Proteasome subunit RPT2a promotes PTGS through repressing RNA quality control in Arabidopsis. Nat Plants. 2019;5:1273-1282 pubmed publisher
|
| Newton K, Wickliffe K, Maltzman A, Dugger D, Reja R, Zhang Y, et al. Activity of caspase-8 determines plasticity between cell death pathways. Nature. 2019;575:679-682 pubmed publisher
|
| Bridges A, Bassler B. The intragenus and interspecies quorum-sensing autoinducers exert distinct control over Vibrio cholerae biofilm formation and dispersal. PLoS Biol. 2019;17:e3000429 pubmed publisher
|
| Gómez Banoy N, Guseh J, Li G, Rubio Navarro A, Chen T, Poirier B, et al. Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans. Nat Med. 2019;25:1739-1747 pubmed publisher
|
| Knyazhanskaya E, Anisenko A, Shadrina O, Kalinina A, Zatsepin T, Zalevsky A, et al. NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase. Retrovirology. 2019;16:30 pubmed publisher
|
| Spiombi E, Angrisani A, Fonte S, De Feudis G, Fabretti F, Cucchi D, et al. KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2. Oncogenesis. 2019;8:64 pubmed publisher
|
| Li B, Ferreira M, Huang M, Camargos L, Yu X, Teixeira R, et al. The receptor-like kinase NIK1 targets FLS2/BAK1 immune complex and inversely modulates antiviral and antibacterial immunity. Nat Commun. 2019;10:4996 pubmed publisher
|
| Terrón Díaz M, Wright S, Agosto M, Lichtarge O, Wensel T. Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors. J Biol Chem. 2019;294:19279-19291 pubmed publisher
|
| Wu K, Jones R, Tachie Menson T, MacArtney T, Wood N, Varghese J, et al. Pathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling. Wellcome Open Res. 2019;4:133 pubmed publisher
|
| Liu R, Olano L, Mirzakhanyan Y, Gershon P, Moss B. Vaccinia Virus Ankyrin-Repeat/F-Box Protein Targets Interferon-Induced IFITs for Proteasomal Degradation. Cell Rep. 2019;29:816-828.e6 pubmed publisher
|
| Centeno P, HERBERGER A, Mun H, Tu C, Nemeth E, Chang W, et al. Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion. Nat Commun. 2019;10:4693 pubmed publisher
|
| Zhang X, Brachner A, Kukolj E, Slade D, Wang Y. SIRT2 deacetylates GRASP55 to facilitate post-mitotic Golgi assembly. J Cell Sci. 2019;132: pubmed publisher
|
| Jones R, Lessoued S, Meier K, Devignot S, Barata García S, Maté M, et al. Structure and function of the Toscana virus cap-snatching endonuclease. Nucleic Acids Res. 2019;47:10914-10930 pubmed publisher
|
| Suzuki H, Shibagaki Y, Hattori S, Matsuoka M. C9-ALS/FTD-linked proline-arginine dipeptide repeat protein associates with paraspeckle components and increases paraspeckle formation. Cell Death Dis. 2019;10:746 pubmed publisher
|
| Guo L, Wang R, Zhang K, Yuan J, Wang J, Wang X, et al. A PINCH-1-Smurf1 signaling axis mediates mechano-regulation of BMPR2 and stem cell differentiation. J Cell Biol. 2019;218:3773-3794 pubmed publisher
|
| Smeland M, McClenaghan C, Roessler H, Savelberg S, Hansen G, Hjellnes H, et al. ABCC9-related Intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9. Nat Commun. 2019;10:4457 pubmed publisher
|
| Bernal M, Yang X, Lisby M, Mazon G. The FANCM family Mph1 helicase localizes to the mitochondria and contributes to mtDNA stability. DNA Repair (Amst). 2019;82:102684 pubmed publisher
|
| Yu T, Gan S, Zhu Q, Dai D, Li N, Wang H, et al. Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24. Nat Commun. 2019;10:4353 pubmed publisher
|
| Pressler K, Mitterer F, Vorkapic D, Reidl J, Oberer M, Schild S. Characterization of Vibrio cholerae's Extracellular Nuclease Xds. Front Microbiol. 2019;10:2057 pubmed publisher
|
| Sawayama T, Nakashima K, Ichimura T, Sakai R, Uekita T. Homophilic complex formation of CDCP1 via the extracellular CUB2 domain facilitates SFK activation and promotes cancer cell migration. Oncol Rep. 2019;: pubmed publisher
|
| Newton K, Wickliffe K, Dugger D, Maltzman A, Roose Girma M, Dohse M, et al. Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis. Nature. 2019;574:428-431 pubmed publisher
|
| Fang P, De Souza C, Minn K, Chien J. Genome-scale CRISPR knockout screen identifies TIGAR as a modifier of PARP inhibitor sensitivity. Commun Biol. 2019;2:335 pubmed publisher
|
| Takano R, Kozuka Hata H, Kondoh D, Bochimoto H, Oyama M, Kato K. A High-Resolution Map of SBP1 Interactomes in Plasmodium falciparum-infected Erythrocytes. iScience. 2019;19:703-714 pubmed publisher
|
| Oya E, Nakagawa R, Yoshimura Y, Tanaka M, Nishibuchi G, Machida S, et al. H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly. EMBO Rep. 2019;20:e48111 pubmed publisher
|
| Yu X, Wang R, Zhang Y, Zhou L, Wang W, Liu H, et al. Skp2-mediated ubiquitination and mitochondrial localization of Akt drive tumor growth and chemoresistance to cisplatin. Oncogene. 2019;38:7457-7472 pubmed publisher
|
| Yu X, Li B, Jang G, Jiang S, Jiang D, Jang J, et al. Orchestration of Processing Body Dynamics and mRNA Decay in Arabidopsis Immunity. Cell Rep. 2019;28:2194-2205.e6 pubmed publisher
|
| Cockman E, Narayan V, Willard B, Shetty S, Copeland P, Driscoll D. Identification of the Selenoprotein S Positive UGA Recoding (SPUR) element and its position-dependent activity. RNA Biol. 2019;16:1682-1696 pubmed publisher
|
| Ding C, Han F, Xiang H, Wang Y, Dou M, Xia X, et al. Role of prostaglandin E2 receptor 4 in the modulation of apoptosis and mitophagy during ischemia/reperfusion injury in the kidney. Mol Med Rep. 2019;20:3337-3346 pubmed publisher
|
| Li D, Chen J, Ai Y, Gu X, Li L, Che D, et al. Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover. Mol Cell. 2019;: pubmed publisher
|
| Ciges Tomas J, Alite C, Humphrey S, Donderis J, Bowring J, Salvatella X, et al. The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature. Nat Commun. 2019;10:3676 pubmed publisher
|
| Helleboid P, Heusel M, Duc J, Piot C, Thorball C, Coluccio A, et al. The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification. EMBO J. 2019;38:e101220 pubmed publisher
|
| Sundaravinayagam D, Rahjouei A, Andreani M, Tupiņa D, Balasubramanian S, Saha T, et al. 53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function. Cell Rep. 2019;28:1389-1399.e6 pubmed publisher
|
| Kelso A, Lopezcolorado F, Bhargava R, Stark J. Distinct roles of RAD52 and POLQ in chromosomal break repair and replication stress response. PLoS Genet. 2019;15:e1008319 pubmed publisher
|
| Cheng J, Baßler J, Fischer P, Lau B, Kellner N, Kunze R, et al. Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration. Mol Cell. 2019;75:1256-1269.e7 pubmed publisher
|
| Ko Y, Kim C, Lee J, Kim D, Kim Y, Yun N, et al. Site-specific phosphorylation of Fbxw7 by Cdk5/p25 and its resulting decreased stability are linked to glutamate-induced excitotoxicity. Cell Death Dis. 2019;10:579 pubmed publisher
|
| Bushkin G, Pincus D, Morgan J, Richardson K, Lewis C, Chan S, et al. m6A modification of a 3' UTR site reduces RME1 mRNA levels to promote meiosis. Nat Commun. 2019;10:3414 pubmed publisher
|
| Jeong K, Ryu I, Park J, Hwang H, Ha H, Park Y, et al. Staufen1 and UPF1 exert opposite actions on the replacement of the nuclear cap-binding complex by eIF4E at the 5' end of mRNAs. Nucleic Acids Res. 2019;47:9313-9328 pubmed publisher
|
| Yang Q, Li R, Lyu Q, Hou L, Liu Z, Sun Q, et al. Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes. Nat Commun. 2019;10:3389 pubmed publisher
|
| Ko Y, Kim S, Lee J, Song M, Park K, Park J, et al. Protein kinase A-induced phosphorylation at the Thr154 affects stability of DJ-1. Parkinsonism Relat Disord. 2019;66:143-150 pubmed publisher
|
| Wild P, Susperregui A, Piazza I, Dörig C, Oke A, Arter M, et al. Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis. Mol Cell. 2019;75:859-874.e4 pubmed publisher
|
| Bufalieri F, Infante P, Bernardi F, Caimano M, Romania P, Moretti M, et al. ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP. Nat Commun. 2019;10:3304 pubmed publisher
|
| Liu K, Jones S, Minis A, Rodriguez J, Molina H, Steller H. PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development. Dev Cell. 2019;50:509-524.e10 pubmed publisher
|
| Ahmed Y, Thoms M, Mitterer V, Sinning I, Hurt E. Crystal structures of Rea1-MIDAS bound to its ribosome assembly factor ligands resembling integrin-ligand-type complexes. Nat Commun. 2019;10:3050 pubmed publisher
|
| Penas C, Maloof M, Stathias V, Long J, Tan S, Mier J, et al. Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis. Nat Commun. 2019;10:3028 pubmed publisher
|
| Masson N, Keeley T, Giuntoli B, White M, Puerta M, Perata P, et al. Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants. Science. 2019;365:65-69 pubmed publisher
|
| Lee M, Hwang Y, Yoon J, Sun J, Harned A, Nagashima K, et al. Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled. J Cell Biol. 2019;: pubmed publisher
|
| Brosnan C, Sarazin A, Lim P, Bologna N, Hirsch Hoffmann M, Voinnet O. Genome-scale, single-cell-type resolution of microRNA activities within a whole plant organ. EMBO J. 2019;38:e100754 pubmed publisher
|
| Shah K, Whitaker R, Busby T, Hu J, Shi B, Wang Z, et al. Specific inhibition of DPY30 activity by ASH2L-derived peptides suppresses blood cancer cell growth. Exp Cell Res. 2019;382:111485 pubmed publisher
|
| De Santis R, Alfano V, de Turris V, Colantoni A, Santini L, Garone M, et al. Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis. Cell Rep. 2019;27:3818-3831.e5 pubmed publisher
|
| Zhu X, He P, Zhang L, Yang S, Zhang H, Zhu D, et al. FBXO22 mediates polyubiquitination and inactivation of LKB1 to promote lung cancer cell growth. Cell Death Dis. 2019;10:486 pubmed publisher
|
| Farmer G, Amune A, Bachelor M, Duong P, Yuan J, Cunningham J. Sniffer cells for the detection of neural Angiotensin II in vitro. Sci Rep. 2019;9:8820 pubmed publisher
|
| Grill S, Bisht K, Tesmer V, Shami A, Hammoud S, Nandakumar J. Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells. Cell Rep. 2019;27:3511-3521.e7 pubmed publisher
|
| Panhale A, Richter F, Ramirez F, Shvedunova M, Manke T, Mittler G, et al. CAPRI enables comparison of evolutionarily conserved RNA interacting regions. Nat Commun. 2019;10:2682 pubmed publisher
|
| Bala Bhaskara Rao K, Katragunta K, Sarma U, Jain N. Abundance of d-2-hydroxyglutarate in G2/M is determined by FOXM1 in mutant IDH1-expressing cells. FEBS Lett. 2019;: pubmed publisher
|
| Zhang X, Crowley V, Wucherpfennig T, Dix M, Cravatt B. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019;15:737-746 pubmed publisher
|
| Haseeb A, Lefebvre V. The SOXE transcription factors-SOX8, SOX9 and SOX10-share a bi-partite transactivation mechanism. Nucleic Acids Res. 2019;47:6917-6931 pubmed publisher
|
| Su T, Izawa T, Thoms M, Yamashita Y, Cheng J, Berninghausen O, et al. Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis. Nature. 2019;: pubmed publisher
|
| Wojtaszek J, Chatterjee N, Najeeb J, Ramos A, Lee M, Bian K, et al. A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy. Cell. 2019;: pubmed publisher
|
| Ikeda K, Freeman M. Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4. J Biol Chem. 2019;: pubmed publisher
|
| Jérôme H, Rudolf M, Lelke M, Pahlmann M, Busch C, Bockholt S, et al. Rift Valley fever virus minigenome system for investigating the role of L protein residues in viral transcription and replication. J Gen Virol. 2019;100:1093-1098 pubmed publisher
|
| Li W, Ward F, McClure K, Chang S, Montabana E, Liras S, et al. Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat Struct Mol Biol. 2019;: pubmed publisher
|
| Bauer C, Schneeberger P, Kortüm F, Altmuller J, Santos Simarro F, Baker L, et al. Gain-of-Function Mutations in KCNN3 Encoding the Small-Conductance Ca2+-Activated K+ Channel SK3 Cause Zimmermann-Laband Syndrome. Am J Hum Genet. 2019;104:1139-1157 pubmed publisher
|
| Pontier D, Picart C, El Baidouri M, Roudier F, Xu T, Lahmy S, et al. The m6A pathway protects the transcriptome integrity by restricting RNA chimera formation in plants. Life Sci Alliance. 2019;2: pubmed publisher
|
| Gogrefe N, Reindl S, Gunther S, Rosenthal M. Structure of a functional cap-binding domain in Rift Valley fever virus L protein. PLoS Pathog. 2019;15:e1007829 pubmed publisher
|
| Elu N, Osinalde N, Beaskoetxea J, Ramirez J, Lectez B, Aloria K, et al. Detailed Dissection of UBE3A-Mediated DDI1 Ubiquitination. Front Physiol. 2019;10:534 pubmed publisher
|
| Zhao J, Lee E, Kim J, Yang R, Chamseddin B, Ni C, et al. Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus. Nat Commun. 2019;10:2300 pubmed publisher
|
| Ramon M, Dang T, Broeckx T, Hulsmans S, Crepin N, Sheen J, et al. Default activation and nuclear translocation of the plant cellular energy sensor SnRK1 regulate metabolic stress responses and development. Plant Cell. 2019;: pubmed publisher
|
| Zhao B, Du F, Xu P, Shu C, Sankaran B, Bell S, et al. A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1. Nature. 2019;: pubmed publisher
|
| Giacalone J, Andorf J, Zhang Q, Burnight E, Ochoa D, Reutzel A, et al. Development of a Molecularly Stable Gene Therapy Vector for the Treatment of RPGR-associated X-linked Retinitis Pigmentosa. Hum Gene Ther. 2019;: pubmed publisher
|
| Cheng L, Yuan B, Ying S, Niu C, Mai H, Guan X, et al. PES1 is a critical component of telomerase assembly and regulates cellular senescence. Sci Adv. 2019;5:eaav1090 pubmed publisher
|
| Zavodszky E, Hegde R. Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors. elife. 2019;8: pubmed publisher
|
| Che L, Yang X, Ge C, El Amouri S, Wang Q, Pan D, et al. Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis. PLoS ONE. 2019;14:e0216553 pubmed publisher
|
| Han X, Yu H, Yuan R, Yang Y, An F, Qin G. Arabidopsis Transcription Factor TCP5 Controls Plant Thermomorphogenesis by Positively Regulating PIF4 Activity. iScience. 2019;: pubmed publisher
|
| Imam S, Kömürlü S, Mattick J, Selyutina A, Talley S, Eddins A, et al. K63-linked Ubiquitin is Required for Restriction of HIV-1 Reverse Transcription and Capsid Destabilization by Rhesus Trim5alpha. J Virol. 2019;: pubmed publisher
|
| Rössler I, Embacher J, Pillet B, Murat G, Liesinger L, Hafner J, et al. Tsr4 and Nap1, two novel members of the ribosomal protein chaperOME. Nucleic Acids Res. 2019;47:6984-7002 pubmed publisher
|
| Marsolier J, Perichon M, Weitzman J, Medjkane S. Secreted parasite Pin1 isomerase stabilizes host PKM2 to reprogram host cell metabolism. Commun Biol. 2019;2:152 pubmed publisher
|
| Gallay K, Blot G, Chahpazoff M, Yajjou Hamalian H, Confort M, de Boisseson C, et al. In vitro, in cellulo and structural characterizations of the interaction between the integrase of Porcine Endogenous Retrovirus A/C and proteins of the BET family. Virology. 2019;532:69-81 pubmed publisher
|
| Kim E, Lisby A, Ma C, Lo N, Ehmer U, Hayer K, et al. Promotion of growth factor signaling as a critical function of β-catenin during HCC progression. Nat Commun. 2019;10:1909 pubmed publisher
|
| Shokri L, Inukai S, Hafner A, Weinand K, Hens K, Vedenko A, et al. A Comprehensive Drosophila melanogaster Transcription Factor Interactome. Cell Rep. 2019;27:955-970.e7 pubmed publisher
|
| Dondelinger Y, Delanghe T, Priem D, Wynosky Dolfi M, Sorobetea D, Rojas Rivera D, et al. Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation. Nat Commun. 2019;10:1729 pubmed publisher
|
| Wang B, Maxwell B, Joo J, Gwon Y, Messing J, Mishra A, et al. ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97. Mol Cell. 2019;74:742-757.e8 pubmed publisher
|
| Tao Z, Hu H, Luo X, Jia B, Du J, He Y. Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis. Nat Plants. 2019;5:424-435 pubmed publisher
|
| Abed M, Verschueren E, Budayeva H, Liu P, Kirkpatrick D, Reja R, et al. The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification. PLoS ONE. 2019;14:e0214110 pubmed publisher
|
| Ye L, Zhang Q, Liuyu T, Xu Z, Zhang M, Luo M, et al. USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA. PLoS Pathog. 2019;15:e1007680 pubmed publisher
|
| Park O, Ha H, Lee Y, Boo S, Kwon D, Song H, et al. Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex. Mol Cell. 2019;74:494-507.e8 pubmed publisher
|
| Baillet N, Krieger S, Journeaux A, Caro V, Tangy F, Vidalain P, et al. Autophagy Promotes Infectious Particle Production of Mopeia and Lassa Viruses. Viruses. 2019;11: pubmed publisher
|
| Meydan S, Marks J, Klepacki D, Sharma V, Baranov P, Firth A, et al. Retapamulin-Assisted Ribosome Profiling Reveals the Alternative Bacterial Proteome. Mol Cell. 2019;74:481-493.e6 pubmed publisher
|
| Liu Z, Mar K, Hanners N, Perelman S, Kanchwala M, Xing C, et al. A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. Nature. 2019;: pubmed publisher
|
| Cheng A, Bouchard Cannon P, Hegazi S, Lowden C, Fung S, Chiang C, et al. SOX2-Dependent Transcription in Clock Neurons Promotes the Robustness of the Central Circadian Pacemaker. Cell Rep. 2019;26:3191-3202.e8 pubmed publisher
|
| Majmudar J, Feng X, Fox N, Nabhan J, Towle T, Ma T, et al. 4'-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function. Medchemcomm. 2019;10:209-220 pubmed publisher
|
| Santra T, Herrero A, Rodriguez J, von Kriegsheim A, Iglesias Martinez L, Schwarzl T, et al. An Integrated Global Analysis of Compartmentalized HRAS Signaling. Cell Rep. 2019;26:3100-3115.e7 pubmed publisher
|
| Rademacher N, Kuropka B, Kunde S, Wahl M, Freund C, Shoichet S. Intramolecular domain dynamics regulate synaptic MAGUK protein interactions. elife. 2019;8: pubmed publisher
|
| Luo F, Liu H, Yang S, Fang Y, Zhao Z, Hu Y, et al. Nonreceptor Tyrosine Kinase c-Abl- and Arg-Mediated IRF3 Phosphorylation Regulates Innate Immune Responses by Promoting Type I IFN Production. J Immunol. 2019;202:2254-2265 pubmed publisher
|
| Hoekzema M, Romilly C, Holmqvist E, Wagner E. Hfq-dependent mRNA unfolding promotes sRNA-based inhibition of translation. EMBO J. 2019;: pubmed publisher
|
| Urdaneta E, Vieira Vieira C, Hick T, Wessels H, Figini D, Moschall R, et al. Purification of cross-linked RNA-protein complexes by phenol-toluol extraction. Nat Commun. 2019;10:990 pubmed publisher
|
| Zhang C, Ye S, Ni J, Cai T, Liu Y, Huang D, et al. STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion. Cell Death Differ. 2019;: pubmed publisher
|
| Zhang M, Cai Z, Zhang M, Wang X, Wang Y, Zhao F, et al. USP20 Promotes Cellular Antiviral Responses via Deconjugating K48-Linked Ubiquitination of MITA. J Immunol. 2019;: pubmed publisher
|
| Kojima M, de Rooij D, Page D. Amplification of a broad transcriptional program by a common factor triggers the meiotic cell cycle in mice. elife. 2019;8: pubmed publisher
|
| Sakai Y, Kassai H, Nakayama H, Fukaya M, Maeda T, Nakao K, et al. Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells. Sci Rep. 2019;9:2799 pubmed publisher
|
| Ali H, Mano M, Braga L, Naseem A, Marini B, Vu D, et al. Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation. Nat Commun. 2019;10:926 pubmed publisher
|
| Gültekin Y, Steller H. Axin proteolysis by Iduna is required for the regulation of stem cell proliferation and intestinal homeostasis in Drosophila. Development. 2019;146: pubmed publisher
|
| Fu Y, Zhang B, Mu T. LMAN1 (ERGIC-53) promotes trafficking of neuroreceptors. Biochem Biophys Res Commun. 2019;511:356-362 pubmed publisher
|
| Chen S, Han C, Miao X, Li X, Yin C, Zou J, et al. Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads. Nat Commun. 2019;10:877 pubmed publisher
|
| Lee S, Lee J, Lee E, Park S, Kang D, Min C, et al. Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-α-Induced Apoptosis via Different Routes. Cell Rep. 2019;26:2194-2211.e6 pubmed publisher
|
| Hu P, Zhao H, Zhu P, Xiao Y, Miao W, Wang Y, et al. Dual regulation of Arabidopsis AGO2 by arginine methylation. Nat Commun. 2019;10:844 pubmed publisher
|
| Kim Y, Choi J, Yang M, Hong S, Lee C, Kubota Y, et al. A MST1-FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis. Nat Commun. 2019;10:838 pubmed publisher
|
| Li X, Gong W, Wang H, Li T, Attri K, Lewis R, et al. O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3. Immunity. 2019;50:576-590.e6 pubmed publisher
|
| Hinshaw S, Harrison S. The structure of the Ctf19c/CCAN from budding yeast. elife. 2019;8: pubmed publisher
|
| Hayashi A, Tanaka K. Short-Homology-Mediated CRISPR/Cas9-Based Method for Genome Editing in Fission Yeast. G3 (Bethesda). 2019;9:1153-1163 pubmed publisher
|
| Teyra J, Singer A, Schmitges F, Jaynes P, Kit Leng Lui S, Polyak M, et al. Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure. 2019;27:590-605.e5 pubmed publisher
|
| Sukonina V, Ma H, Zhang W, Bartesaghi S, Subhash S, Heglind M, et al. FOXK1 and FOXK2 regulate aerobic glycolysis. Nature. 2019;566:279-283 pubmed publisher
|
| Etoh K, Fukuda M. Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors. J Cell Sci. 2019;132: pubmed publisher
|
| Hodatsu A, Fujino N, Uyama Y, Tsukamoto O, Imai Okazaki A, Yamazaki S, et al. Impact of cardiac myosin light chain kinase gene mutation on development of dilated cardiomyopathy. ESC Heart Fail. 2019;6:406-415 pubmed publisher
|
| Zawerton A, Yao B, Yeager J, Pippucci T, Haseeb A, Smith J, et al. De Novo SOX4 Variants Cause a Neurodevelopmental Disease Associated with Mild Dysmorphism. Am J Hum Genet. 2019;104:246-259 pubmed publisher
|
| Jiang D, Song Y, Cao W, Wang X, Jiang D, Lv Z, et al. p53-independent role of MYC mutant T58A in the proliferation and apoptosis of breast cancer cells. Oncol Lett. 2019;17:1071-1079 pubmed publisher
|
| Kusakabe S, Suzuki T, Sugiyama Y, Haga S, Horike K, Tokunaga M, et al. USP15 Participates in Hepatitis C Virus Propagation through Regulation of Viral RNA Translation and Lipid Droplet Formation. J Virol. 2019;93: pubmed publisher
|
| Springgay L, Fitzpatrick K, Park B, Estep R, Wong S. Rhesus Macaque Rhadinovirus Encodes a Viral Interferon Regulatory Factor To Disrupt Promyelocytic Leukemia Nuclear Bodies and Antagonize Type I Interferon Signaling. J Virol. 2019;93: pubmed publisher
|
| Zhang Q, Giacalone J, Searby C, Stone E, Tucker B, Sheffield V. Disruption of RPGR protein interaction network is the common feature of RPGR missense variations that cause XLRP. Proc Natl Acad Sci U S A. 2019;116:1353-1360 pubmed publisher
|
| Idris M, Butcher N, Minchin R. The MBNL/CELF Splicing Factors Regulate Cytosolic Sulfotransferase 4A1 Protein Expression during Cell Differentiation. Drug Metab Dispos. 2019;47:314-319 pubmed publisher
|
| Nishibuchi G, Machida S, Nakagawa R, Yoshimura Y, Hiragami Hamada K, Abe Y, et al. Mitotic phosphorylation of HP1α regulates its cell cycle-dependent chromatin binding. J Biochem. 2019;165:433-446 pubmed publisher
|
| Wu R, Dang F, Li P, Wang P, Xu Q, Liu Z, et al. The Circadian Protein Period2 Suppresses mTORC1 Activity via Recruiting Tsc1 to mTORC1 Complex. Cell Metab. 2019;29:653-667.e6 pubmed publisher
|
| Harth S, Ten Haaf A, Loew C, Frisch C, Knappik A. Generation by phage display and characterization of drug-target complex-specific antibodies for pharmacokinetic analysis of biotherapeutics. MAbs. 2019;11:178-190 pubmed publisher
|
| Antonucci L, Di Magno L, D Amico D, Manni S, Serrao S, Di Pastena F, et al. Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation. Int J Oncol. 2019;54:505-514 pubmed publisher
|
| Liuyu T, Yu K, Ye L, Zhang Z, Zhang M, Ren Y, et al. Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS. Cell Res. 2019;29:67-79 pubmed publisher
|
| Jung S, Hwang H, Kang D, Park H, Lee H, Jeong D, et al. mTOR kinase leads to PTEN-loss-induced cellular senescence by phosphorylating p53. Oncogene. 2019;38:1639-1650 pubmed publisher
|
| Zhuang K, Kong F, Zhang S, Meng C, Yang M, Liu Z, et al. Whirly1 enhances tolerance to chilling stress in tomato via protection of photosystem II and regulation of starch degradation. New Phytol. 2019;221:1998-2012 pubmed publisher
|
| Huang L, Yu L, Zhang X, Fan B, Wang F, Dai Y, et al. Autophagy regulates glucose-mediated root meristem activity by modulating ROS production in Arabidopsis. Autophagy. 2019;15:407-422 pubmed publisher
|
| Ohno M, Negishi M. GR Utilizes a Co-Chaperone Cytoplasmic CAR Retention Protein to Form an N/C Interaction. Nucl Recept Signal. 2018;15:1550762918801072 pubmed publisher
|
| Campos J, Doratioto T, Videira N, Ribeiro Filho H, Batista F, Fattori J, et al. Protein Disulfide Isomerase Modulates the Activation of Thyroid Hormone Receptors. Front Endocrinol (Lausanne). 2018;9:784 pubmed publisher
|
| Zhu K, Tang Y, Xu X, Dang H, Tang L, Wang X, et al. Non-proteolytic ubiquitin modification of PPARγ by Smurf1 protects the liver from steatosis. PLoS Biol. 2018;16:e3000091 pubmed publisher
|
| Kühn M, Schmidt F, Farthing N, Rossmann F, Helm B, Wilson L, et al. Spatial arrangement of several flagellins within bacterial flagella improves motility in different environments. Nat Commun. 2018;9:5369 pubmed publisher
|
| Naito R, Kassai H, Sakai Y, Schönherr S, Fukaya M, Schwarzer C, et al. New Features on the Expression and Trafficking of mGluR1 Splice Variants Exposed by Two Novel Mutant Mouse Lines. Front Mol Neurosci. 2018;11:439 pubmed publisher
|
| Bhattacharya D, Rothstein M, Azambuja A, Simões Costa M. Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis. elife. 2018;7: pubmed publisher
|
| Asai S, Furzer O, Cevik V, Kim D, Ishaque N, Goritschnig S, et al. A downy mildew effector evades recognition by polymorphism of expression and subcellular localization. Nat Commun. 2018;9:5192 pubmed publisher
|
| McClurg U, McCracken S, Butler L, Riabowol K, Binda O. Ex vivo Culture and Lentiviral Transduction of Benign Prostatic Hyperplasia (BPH) Samples. Bio Protoc. 2018;8: pubmed publisher
|
| Li M, Vera N, Yang Y, Zhang B, Ni W, Ziso Qejvanaj E, et al. Adipocyte OGT governs diet-induced hyperphagia and obesity. Nat Commun. 2018;9:5103 pubmed publisher
|
| Fu Y, Han D, Wang Y, Di X, Yu H, Mu T. Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABAA receptors. PLoS ONE. 2018;13:e0207948 pubmed publisher
|
| De Bruyne M, Hoste L, Bogaert D, Van den Bossche L, Tavernier S, Parthoens E, et al. A CARD9 Founder Mutation Disrupts NF-κB Signaling by Inhibiting BCL10 and MALT1 Recruitment and Signalosome Formation. Front Immunol. 2018;9:2366 pubmed publisher
|
| Høyland Kroghsbo N, Muñoz K, Bassler B. Temperature, by Controlling Growth Rate, Regulates CRISPR-Cas Activity in Pseudomonas aeruginosa. MBio. 2018;9: pubmed publisher
|
| Lan Y, Xiao X, Luo Y, He Z, Song X. FEZF1 is an Independent Predictive Factor for Recurrence and Promotes Cell Proliferation and Migration in Cervical Cancer. J Cancer. 2018;9:3929-3938 pubmed publisher
|
| Tan P, Ye Y, He L, Xie J, Jing J, Ma G, et al. TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10. PLoS Biol. 2018;16:e3000051 pubmed publisher
|
| Yan W, Yu H, Li W, Li F, Wang S, Yu N, et al. Plk1 promotes the migration of human lung adenocarcinoma epithelial cells via STAT3 signaling. Oncol Lett. 2018;16:6801-6807 pubmed publisher
|
| Mayr J, Lau K, Lai J, Gagarinov I, Shi Y, McAtamney S, et al. Unravelling the Role of O-glycans in Influenza A Virus Infection. Sci Rep. 2018;8:16382 pubmed publisher
|
| Miyagawa T, Koteishi H, Kamimura Y, Miyanaga Y, Takeshita K, Nakagawa A, et al. Structural basis of Gip1 for cytosolic sequestration of G protein in wide-range chemotaxis. Nat Commun. 2018;9:4635 pubmed publisher
|
| Chang L, Azzolin L, Di Biagio D, Zanconato F, Battilana G, Lucon Xiccato R, et al. The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ. Nature. 2018;563:265-269 pubmed publisher
|
| Deng Y, Pakdel M, Blank B, Sundberg E, Burd C, von Blume J. Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network. Dev Cell. 2018;47:464-478.e8 pubmed publisher
|
| Wei J, Chen L, Li F, Yuan Y, Wang Y, Xia W, et al. HRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination. EMBO J. 2018;37: pubmed publisher
|
| Huang P, Low P, Wang I, Hsu S, Angata T. Soluble Siglec-14 glycan-recognition protein is generated by alternative splicing and suppresses myeloid inflammatory responses. J Biol Chem. 2018;293:19645-19658 pubmed publisher
|
| Huang Z, Zhao J, Deng W, Chen Y, Shang J, Song K, et al. Identification of a cellularly active SIRT6 allosteric activator. Nat Chem Biol. 2018;14:1118-1126 pubmed publisher
|
| Russo I, Di Benedetto G, Kaganovich A, Ding J, Mercatelli D, Morari M, et al. Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4. J Neuroinflammation. 2018;15:297 pubmed publisher
|
| Yien Y, Shi J, Chen C, Cheung J, Grillo A, Shrestha R, et al. FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity. J Biol Chem. 2018;293:19797-19811 pubmed publisher
|
| Kien B, Grond S, Haemmerle G, Lass A, Eichmann T, Radner F. ABHD5 stimulates PNPLA1-mediated ω-O-acylceramide biosynthesis essential for a functional skin permeability barrier. J Lipid Res. 2018;59:2360-2367 pubmed publisher
|
| Zhang Y, Lin Z, Wang M, Lin H. Selective Usage of Isozymes for Stress Response. ACS Chem Biol. 2018;13:3059-3064 pubmed publisher
|
| Katayama K, Noguchi K, Sugimoto Y. Heat shock protein 90 inhibitors overcome the resistance to Fms-like tyrosine kinase 3 inhibitors in acute myeloid leukemia. Oncotarget. 2018;9:34240-34258 pubmed publisher
|
| Ying Z, Pan C, Shao T, Liu L, Li L, Guo D, et al. Mixed Lineage Kinase Domain-like Protein MLKL Breaks Down Myelin following Nerve Injury. Mol Cell. 2018;72:457-468.e5 pubmed publisher
|
| Tseng H, Samarelli A, Kammerer P, Scholze S, Ziegler T, Immler R, et al. LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow. J Cell Sci. 2018;131: pubmed publisher
|
| Jeon J, McGinty R, Muir T, Kim J, Kim J. Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation. Nucleic Acids Res. 2018;46:11129-11143 pubmed publisher
|
| Vallon M, Yuki K, Nguyen T, Chang J, Yuan J, Siepe D, et al. A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability. Cell Rep. 2018;25:339-349.e9 pubmed publisher
|
| Delgado Benito V, Rosen D, Wang Q, Gazumyan A, Pai J, Oliveira T, et al. The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination. Mol Cell. 2018;72:636-649.e8 pubmed publisher
|
| Thoms M, Mitterer V, Kater L, Falquet L, Beckmann R, Kressler D, et al. Suppressor mutations in Rpf2-Rrs1 or Rpl5 bypass the Cgr1 function for pre-ribosomal 5S RNP-rotation. Nat Commun. 2018;9:4094 pubmed publisher
|
| Harms F, Kloth K, Bley A, Denecke J, Santer R, Lessel D, et al. Activating Mutations in PAK1, Encoding p21-Activated Kinase 1, Cause a Neurodevelopmental Disorder. Am J Hum Genet. 2018;103:579-591 pubmed publisher
|
| Tveriakhina L, Schuster Gossler K, Jarrett S, Andrawes M, Rohrbach M, Blacklow S, et al. The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro. elife. 2018;7: pubmed publisher
|
| Kecman T, Kus K, Heo D, Duckett K, Birot A, Liberatori S, et al. Elongation/Termination Factor Exchange Mediated by PP1 Phosphatase Orchestrates Transcription Termination. Cell Rep. 2018;25:259-269.e5 pubmed publisher
|
| Beckers A, Ott T, Schuster Gossler K, Boldt K, Alten L, Ueffing M, et al. The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary function in mice. Sci Rep. 2018;8:14678 pubmed publisher
|
| Weber K, Roelandt R, Bruggeman I, Estornes Y, Vandenabeele P. Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis. Commun Biol. 2018;1:6 pubmed publisher
|
| Meineke B, Heimgärtner J, Lafranchi L, Elsässer S. Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal Pyrrolysyl tRNA/Aminoacyl-tRNA Synthetase Pairs in Mammalian Cells. ACS Chem Biol. 2018;13:3087-3096 pubmed publisher
|
| Bartlett E, Bonfiglio J, Prokhorova E, Colby T, Zobel F, Ahel I, et al. Interplay of Histone Marks with Serine ADP-Ribosylation. Cell Rep. 2018;24:3488-3502.e5 pubmed publisher
|
| Song Y, Kubota A, Kwon M, Covington M, Lee N, Taagen E, et al. Molecular basis of flowering under natural long-day conditions in Arabidopsis. Nat Plants. 2018;4:824-835 pubmed publisher
|
| Suzuki H, Shibagaki Y, Hattori S, Matsuoka M. The proline-arginine repeat protein linked to C9-ALS/FTD causes neuronal toxicity by inhibiting the DEAD-box RNA helicase-mediated ribosome biogenesis. Cell Death Dis. 2018;9:975 pubmed publisher
|
| Lee W, Lee S, Yim S, Kim D, Kim H, Jeong S, et al. Whole Exome Sequencing Identifies a Novel Hedgehog-Interacting Protein G516R Mutation in Locally Advanced Papillary Thyroid Cancer. Int J Mol Sci. 2018;19: pubmed publisher
|
| Jin H, Choi S, Kang M, Yun S, Kwon D, Noh Y, et al. Salicylic acid-induced transcriptional reprogramming by the HAC-NPR1-TGA histone acetyltransferase complex in Arabidopsis. Nucleic Acids Res. 2018;46:11712-11725 pubmed publisher
|
| Vigano M, Bieli D, Schaefer J, Jakob R, Matsuda S, Maier T, et al. DARPins recognizing mTFP1 as novel reagents for in vitro and in vivo protein manipulations. Biol Open. 2018;7: pubmed publisher
|
| Choe J, Lin S, Zhang W, Liu Q, Wang L, Ramírez Moya J, et al. mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis. Nature. 2018;561:556-560 pubmed publisher
|
| Fellermeier Kopf S, Gieseke F, Sahin U, Muller D, Pfizenmaier K, Kontermann R. Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans. Oncoimmunology. 2018;7:e1471442 pubmed publisher
|
| Zanconato F, Battilana G, Forcato M, Filippi L, Azzolin L, Manfrin A, et al. Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4. Nat Med. 2018;24:1599-1610 pubmed publisher
|
| Li Z, Jiang D, He Y. FRIGIDA establishes a local chromosomal environment for FLOWERING LOCUS C mRNA production. Nat Plants. 2018;4:836-846 pubmed publisher
|
| Bellelli R, Belan O, Pye V, Clement C, Maslen S, Skehel J, et al. POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication. Mol Cell. 2018;72:112-126.e5 pubmed publisher
|
| Lee J, Ko Y, Chung Y, Yun N, Kim M, Kim K, et al. The acetylation of cyclin-dependent kinase 5 at lysine 33 regulates kinase activity and neurite length in hippocampal neurons. Sci Rep. 2018;8:13676 pubmed publisher
|
| Wang H, Guo W, Mitra J, Hegde P, Vandoorne T, Eckelmann B, et al. Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis. Nat Commun. 2018;9:3683 pubmed publisher
|
| Ayhan F, Perez B, Shorrock H, Zu T, Bañez Coronel M, Reid T, et al. SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F. EMBO J. 2018;37: pubmed publisher
|
| Xu C, Peng Y, Zhang Q, Xu X, Kong X, Shi W. USP4 positively regulates RLR-induced NF-?B activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication. Sci Rep. 2018;8:13418 pubmed publisher
|
| Lea W, Parnell S, Wallace D, Calvet J, Zelenchuk L, Alvarez N, et al. Human-Specific Abnormal Alternative Splicing of Wild-Type PKD1 Induces Premature Termination of Polycystin-1. J Am Soc Nephrol. 2018;29:2482-2492 pubmed publisher
|
| Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, et al. Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease. elife. 2018;7: pubmed publisher
|
| Ten Caten F, Vencio R, Lorenzetti A, Zaramela L, Santana A, Koide T. Internal RNAs overlapping coding sequences can drive the production of alternative proteins in archaea. RNA Biol. 2018;15:1119-1132 pubmed publisher
|
| Choi J, Fan C, Kim D, Sharif M, An H, Park Y. Elucidating the transactivation domain of the pleiotropic transcription factor Myrf. Sci Rep. 2018;8:13075 pubmed publisher
|
| Yoon J, Hwang Y, Lee M, Sun J, Cho H, Knapik L, et al. TBC1d24-ephrinB2 interaction regulates contact inhibition of locomotion in neural crest cell migration. Nat Commun. 2018;9:3491 pubmed publisher
|
| Khan I, Krishnaswamy S, Sabale M, Groth D, Wijaya L, Morici M, et al. Efficient production of a mature and functional gamma secretase protease. Sci Rep. 2018;8:12834 pubmed publisher
|
| Jády B, Ketele A, Kiss T. Dynamic association of human mRNP proteins with mitochondrial tRNAs in the cytosol. RNA. 2018;: pubmed publisher
|
| Vervoort S, Lourenço A, Tufegdzic Vidakovic A, Mocholí E, Sandoval J, Rueda O, et al. SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis. Nucleic Acids Res. 2018;46:9578-9590 pubmed publisher
|
| Ichikawa Y, Saitoh N, Kaufman P. An asymmetric centromeric nucleosome. elife. 2018;7: pubmed publisher
|
| Alon M, Arafeh R, Lee J, Madan S, Kalaora S, Nagler A, et al. CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma. Oncotarget. 2018;9:31264-31277 pubmed publisher
|
| Aichem A, Anders S, Catone N, Rößler P, Stotz S, Berg A, et al. The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation. Nat Commun. 2018;9:3321 pubmed publisher
|
| Brahma S, Ngubo M, Paul S, Udugama M, Bartholomew B. The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling. Nat Commun. 2018;9:3309 pubmed publisher
|
| Hans F, Eckert M, von Zweydorf F, Gloeckner C, Kahle P. Identification and characterization of ubiquitinylation sites in TAR DNA-binding protein of 43 kDa (TDP-43). J Biol Chem. 2018;293:16083-16099 pubmed publisher
|
| Huang C, Sun H, Wang Z, Liu Y, Cheng X, Liu J, et al. Increased Krüppel-like factor 12 impairs embryo attachment via downregulation of leukemia inhibitory factor in women with recurrent implantation failure. Cell Death Discov. 2018;4:23 pubmed publisher
|
| Gerber K, Squires K, Hepler J. 14-3-3γ binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:Gαi-AlF4- signaling complex and RGS14 nuclear localization. J Biol Chem. 2018;293:14616-14631 pubmed publisher
|
| Scott A, Walker S, Krank J, Wilkinson A, Johnson K, Lewis E, et al. AIF promotes a JNK1-mediated cadherin switch independently of respiratory chain stabilization. J Biol Chem. 2018;293:14707-14722 pubmed publisher
|
| Ovejero S, Ayala P, Malumbres M, Pimentel Muiños F, Bueno A, Sacristán M. Biochemical analyses reveal amino acid residues critical for cell cycle-dependent phosphorylation of human Cdc14A phosphatase by cyclin-dependent kinase 1. Sci Rep. 2018;8:11871 pubmed publisher
|
| Bagchi R, Ferguson B, Stratton M, Hu T, Cavasin M, Sun L, et al. HDAC11 suppresses the thermogenic program of adipose tissue via BRD2. JCI Insight. 2018;3: pubmed publisher
|
| Yang Z, Qian S, Scheid R, Lu L, Chen X, Liu R, et al. EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis. Nat Genet. 2018;50:1247-1253 pubmed publisher
|
| Zheng Y, Liu Q, Wu Y, Ma L, Zhang Z, Liu T, et al. Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1-caspase-1 axis. EMBO J. 2018;37: pubmed publisher
|
| Mishra S, Van Rechem C, Pal S, Clarke T, Chakraborty D, Mahan S, et al. Cross-talk between Lysine-Modifying Enzymes Controls Site-Specific DNA Amplifications. Cell. 2018;174:803-817.e16 pubmed publisher
|
| Brzek A, Cichocka M, Dolata J, Juzwa W, Schumperli D, Raczynska K. Positive cofactor 4 (PC4) contributes to the regulation of replication-dependent canonical histone gene expression. BMC Mol Biol. 2018;19:9 pubmed publisher
|
| Sonnenschein H, Lawrence K, Wittenberg K, Slykas F, Dohleman E, Knoublauch J, et al. Suppressor of IKKepsilon forms direct interactions with cytoskeletal proteins, tubulin and α-actinin, linking innate immunity to the cytoskeleton. FEBS Open Bio. 2018;8:1064-1082 pubmed publisher
|
| Xiong S, Lorenzen K, Couzens A, Templeton C, Rajendran D, Mao D, et al. Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment. Structure. 2018;26:1101-1115.e6 pubmed publisher
|
| Bonacci T, Suzuki A, Grant G, Stanley N, Cook J, Brown N, et al. Cezanne/OTUD7B is a cell cycle-regulated deubiquitinase that antagonizes the degradation of APC/C substrates. EMBO J. 2018;37: pubmed publisher
|
| Bhargava R, Sandhu M, Muk S, Lee G, Vaidehi N, Stark J. C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains. Nat Commun. 2018;9:2484 pubmed publisher
|
| Chiarella E, Aloisio A, Codispoti B, Nappo G, Scicchitano S, Lucchino V, et al. ZNF521 Has an Inhibitory Effect on the Adipogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells. Stem Cell Rev. 2018;14:901-914 pubmed publisher
|
| Lan Y, Xiao X, He Z, Luo Y, Wu C, Li L, et al. Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer. Nucleic Acids Res. 2018;46:5809-5821 pubmed publisher
|
| Qian S, Lv X, Scheid R, Lu L, Yang Z, Chen W, et al. Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL. Nat Commun. 2018;9:2425 pubmed publisher
|
| Murillo de Ozores A, Rodríguez Gama A, Bazúa Valenti S, Leyva Ríos K, Vazquez N, Pacheco Alvarez D, et al. C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity. J Biol Chem. 2018;293:12209-12221 pubmed publisher
|
| Markolovic S, Zhuang Q, Wilkins S, Eaton C, Abboud M, Katz M, et al. The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases. Nat Chem Biol. 2018;14:688-695 pubmed publisher
|
| Ramos Alonso L, Romero A, Soler M, Perea García A, Alepuz P, Puig S, et al. Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency. PLoS Genet. 2018;14:e1007476 pubmed publisher
|
| Dionne U, Chartier F, López de Los Santos Y, Lavoie N, Bernard D, Banerjee S, et al. Direct Phosphorylation of SRC Homology 3 Domains by Tyrosine Kinase Receptors Disassembles Ligand-Induced Signaling Networks. Mol Cell. 2018;70:995-1007.e11 pubmed publisher
|
| Xia X, Katzenell S, Reinhart E, Bauer K, Pellegrini M, Ragusa M. A pseudo-receiver domain in Atg32 is required for mitophagy. Autophagy. 2018;:1-9 pubmed publisher
|
| Wolff D, Lee M, Jothi M, Mal M, Li F, Mal A. Camptothecin exhibits topoisomerase1-independent KMT1A suppression and myogenic differentiation in alveolar rhabdomyosarcoma cells. Oncotarget. 2018;9:25796-25807 pubmed publisher
|
| Kang Y, Kuybeda O, de Waal P, Mukherjee S, Van Eps N, Dutka P, et al. Cryo-EM structure of human rhodopsin bound to an inhibitory G protein. Nature. 2018;558:553-558 pubmed publisher
|
| Oikonomidi I, Burbridge E, Cavadas M, Sullivan G, Collis B, Naegele H, et al. iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE. elife. 2018;7: pubmed publisher
|
| Youmans D, Schmidt J, Cech T. Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunits. Genes Dev. 2018;32:794-805 pubmed publisher
|
| Dovey C, Diep J, Clarke B, Hale A, McNamara D, Guo H, et al. MLKL Requires the Inositol Phosphate Code to Execute Necroptosis. Mol Cell. 2018;70:936-948.e7 pubmed publisher
|
| Hua X, Li B, Song L, Hu C, Li X, Wang D, et al. Stimulator of interferon genes (STING) provides insect antiviral immunity by promoting Dredd caspase-mediated NF-κB activation. J Biol Chem. 2018;293:11878-11890 pubmed publisher
|
| Renner T, Bélanger K, Goodwin L, Campbell M, Langlois M. Characterization of molecular attributes that influence LINE-1 restriction by all seven human APOBEC3 proteins. Virology. 2018;520:127-136 pubmed publisher
|
| Ji Q, Qi D, Xu X, Xu Y, Goodman S, Kang L, et al. Cryptotanshinone Protects Cartilage against Developing Osteoarthritis through the miR-106a-5p/GLIS3 Axis. Mol Ther Nucleic Acids. 2018;11:170-179 pubmed publisher
|
| Derrien B, Clavel M, Baumberger N, Iki T, Sarazin A, Hacquard T, et al. A Suppressor Screen for AGO1 Degradation by the Viral F-Box P0 Protein Uncovers a Role for AGO DUF1785 in sRNA Duplex Unwinding. Plant Cell. 2018;30:1353-1374 pubmed publisher
|
| Ito Ishida A, Yamalanchili H, Shao Y, BAKER S, Heckman L, Lavery L, et al. Genome-wide distribution of linker histone H1.0 is independent of MeCP2. Nat Neurosci. 2018;21:794-798 pubmed publisher
|
| Hong H, An O, Chan T, Ng V, Kwok H, Lin J, et al. Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer. Nucleic Acids Res. 2018;46:7953-7969 pubmed publisher
|
| Deci M, Ferguson S, Scatigno S, Nguyen J. Modulating Macrophage Polarization through CCR2 Inhibition and Multivalent Engagement. Mol Pharm. 2018;15:2721-2731 pubmed publisher
|
| Fulcher L, Bozatzi P, Tachie Menson T, Wu K, Cummins T, Bufton J, et al. The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms. Sci Signal. 2018;11: pubmed publisher
|
| Ramirez J, Lectez B, Osinalde N, Sivá M, Elu N, Aloria K, et al. Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome. Hum Mol Genet. 2018;27:1955-1971 pubmed publisher
|
| Tsukamoto Y, Ikeda S, Uwai K, Taguchi R, Chayama K, Sakaguchi T, et al. Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction. PLoS ONE. 2018;13:e0197664 pubmed publisher
|
| Venegas L, Kall S, Bankole O, Lavie A, Kay B. Generating a recombinant phosphothreonine-binding domain for a phosphopeptide of the human transcription factor, c-Myc. N Biotechnol. 2018;45:36-44 pubmed publisher
|
| Kim K, Kim J, Kim I, Seong S, Kim N. TRIM38 regulates NF-κB activation through TAB2 degradation in osteoclast and osteoblast differentiation. Bone. 2018;113:17-28 pubmed publisher
|
| Koliopoulos M, Lethier M, van der Veen A, Haubrich K, Hennig J, Kowalinski E, et al. Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition. Nat Commun. 2018;9:1820 pubmed publisher
|
| Zhou M, Palanca A, Law J. Locus-specific control of the de novo DNA methylation pathway in Arabidopsis by the CLASSY family. Nat Genet. 2018;50:865-873 pubmed publisher
|
| Liu Q, Wu Y, Qin Y, Hu J, Xie W, Qin F, et al. Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses. Sci Adv. 2018;4:eaar2824 pubmed publisher
|
| Ribeiro de Almeida C, Dhir S, Dhir A, Moghaddam A, Sattentau Q, Meinhart A, et al. RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination. Mol Cell. 2018;70:650-662.e8 pubmed publisher
|
| Kijima T, Prince T, Tigue M, Yim K, Schwartz H, Beebe K, et al. HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation. Sci Rep. 2018;8:6976 pubmed publisher
|
| Wiederstein J, Nolte H, Günther S, Piller T, Baraldo M, Kostin S, et al. Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown. Cell Rep. 2018;23:1342-1356 pubmed publisher
|
| Huang C, Oberbeck N, Hsiao Y, Liu P, Johnson A, Dixit V, et al. Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity. Structure. 2018;26:767-777.e5 pubmed publisher
|
| Sime W, Niu Q, Abassi Y, Masoumi K, Zarrizi R, Køhler J, et al. BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma. Cell Death Dis. 2018;9:458 pubmed publisher
|
| Kharel Y, Agah S, Huang T, Mendelson A, Eletu O, Barkey Bircann P, et al. Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors. PLoS ONE. 2018;13:e0192179 pubmed publisher
|
| Zou A, Magee N, Deng F, Lehn S, Zhong C, Zhang Y. Hepatocyte nuclear receptor SHP suppresses inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis. J Biol Chem. 2018;293:8656-8671 pubmed publisher
|
| Cho H, Rambout X, Gleghorn M, Nguyen P, Phipps C, Miyoshi K, et al. Transcriptional coactivator PGC-1? contains a novel CBP80-binding motif that orchestrates efficient target gene expression. Genes Dev. 2018;32:555-567 pubmed publisher
|
| Arribas Hernández L, Bressendorff S, Hansen M, Poulsen C, Erdmann S, Brodersen P. An m6A-YTH Module Controls Developmental Timing and Morphogenesis in Arabidopsis. Plant Cell. 2018;30:952-967 pubmed publisher
|
| Maddalena A, Dell Aquila F, Giovannelli P, Tiberi P, Wanderlingh L, Montefusco S, et al. High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction In Vitro and in Mouse Retina. Hum Gene Ther. 2018;29:886-901 pubmed publisher
|
| Li Q, Lin L, Tong Y, Liu Y, Mou J, Wang X, et al. TRIM29 negatively controls antiviral immune response through targeting STING for degradation. Cell Discov. 2018;4:13 pubmed publisher
|
| Kwasna D, Abdul Rehman S, Natarajan J, Matthews S, Madden R, De Cesare V, et al. Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability. Mol Cell. 2018;70:150-164.e6 pubmed publisher
|
| Higa R, Hanada T, Teranishi H, Miki D, Seo K, Hada K, et al. CD105 maintains the thermogenic program of beige adipocytes by regulating Smad2 signaling. Mol Cell Endocrinol. 2018;474:184-193 pubmed publisher
|
| Chen X, Liu M, Tian Y, Li J, Qi Y, Zhao D, et al. Cryo-EM structure of human mTOR complex 2. Cell Res. 2018;28:518-528 pubmed publisher
|
| Hewings D, Heideker J, Ma T, AhYoung A, El Oualid F, Amore A, et al. Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes. Nat Commun. 2018;9:1162 pubmed publisher
|
| Ahn J, Lee H, Lee J, Lee Y, Park J, Kim S, et al. nc886 is induced by TGF-β and suppresses the microRNA pathway in ovarian cancer. Nat Commun. 2018;9:1166 pubmed publisher
|
| Mazel Sanchez B, Boal Carvalho I, Silva F, Dijkman R, Schmolke M. H5N1 Influenza A Virus PB1-F2 Relieves HAX-1-Mediated Restriction of Avian Virus Polymerase PA in Human Lung Cells. J Virol. 2018;92: pubmed publisher
|
| Maticzka D, Ilik I, Aktas T, Backofen R, Akhtar A. uvCLAP is a fast and non-radioactive method to identify in vivo targets of RNA-binding proteins. Nat Commun. 2018;9:1142 pubmed publisher
|
| Fleith R, Mears H, Leong X, Sanford T, Emmott E, Graham S, et al. IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA. Nucleic Acids Res. 2018;46:5269-5285 pubmed publisher
|
| Raab M, Sanhaji M, Matthess Y, Hörlin A, Lorenz I, Dötsch C, et al. PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells. Nat Commun. 2018;9:1106 pubmed publisher
|
| Hutt M, Fellermeier Kopf S, Seifert O, Schmitt L, Pfizenmaier K, Kontermann R. Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells. Oncotarget. 2018;9:11322-11335 pubmed publisher
|
| Purandare N, Somayajulu M, Huttemann M, Grossman L, Aras S. The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction. J Biol Chem. 2018;293:6517-6529 pubmed publisher
|
| Matthes F, Hettich M, Schilling J, Flores Dominguez D, Blank N, Wiglenda T, et al. Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis. Cell Death Discov. 2018;4:4 pubmed publisher
|
| Hewawasam G, Dhatchinamoorthy K, Mattingly M, Seidel C, Gerton J. Chromatin assembly factor-1 (CAF-1) chaperone regulates Cse4 deposition into chromatin in budding yeast. Nucleic Acids Res. 2018;46:4440-4455 pubmed publisher
|
| Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, et al. Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis. Nat Commun. 2018;9:976 pubmed publisher
|
| Bozatzi P, Dingwell K, Wu K, Cooper F, Cummins T, Hutchinson L, et al. PAWS1 controls Wnt signalling through association with casein kinase 1α. EMBO Rep. 2018;19: pubmed publisher
|
| Matthes F, Massari S, Bochicchio A, Schorpp K, Schilling J, Weber S, et al. Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder. ACS Chem Neurosci. 2018;9:1399-1408 pubmed publisher
|
| Palazzo L, Leidecker O, Prokhorova E, Dauben H, Matic I, Ahel I. Serine is the major residue for ADP-ribosylation upon DNA damage. elife. 2018;7: pubmed publisher
|
| Liu K, Zhang L, Zhao Q, Zhao Z, Zhi F, Qin Y, et al. SKP2 attenuates NF-κB signaling by mediating IKKβ degradation through autophagy. J Mol Cell Biol. 2018;10:205-215 pubmed publisher
|
| Ravi A, Guo S, Rasala B, Tran M, Mayfield S, Nikolov Z. Separation Options for Phosphorylated Osteopontin from Transgenic Microalgae Chlamydomonas reinhardtii. Int J Mol Sci. 2018;19: pubmed publisher
|
| Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, et al. Transcriptional Regulation of the Warburg Effect in Cancer by SIX1. Cancer Cell. 2018;33:368-385.e7 pubmed publisher
|
| Li S, Liu K, Zhou B, Li M, Zhang S, Zeng L, et al. MAC3A and MAC3B, Two Core Subunits of the MOS4-Associated Complex, Positively Influence miRNA Biogenesis. Plant Cell. 2018;30:481-494 pubmed publisher
|
| Kuliyev E, Gingras S, Guy C, Howell S, Vogel P, Pelletier S. Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron Viability. J Neurosci. 2018;38:2615-2630 pubmed publisher
|
| Lu L, Chen X, Qian S, Zhong X. The plant-specific histone residue Phe41 is important for genome-wide H3.1 distribution. Nat Commun. 2018;9:630 pubmed publisher
|
| Vogel M, Weigand J, Kluge B, Grez M, Suess B. A small, portable RNA device for the control of exon skipping in mammalian cells. Nucleic Acids Res. 2018;46:e48 pubmed publisher
|
| Roy G, Martin T, Barnes A, Wang J, Jimenez R, Rice M, et al. A novel bicistronic gene design couples stable cell line selection with a fucose switch in a designer CHO host to produce native and afucosylated glycoform antibodies. MAbs. 2018;10:416-430 pubmed publisher
|
| Liang T, Mei S, Shi C, Yang Y, Peng Y, Ma L, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev Cell. 2018;44:512-523.e5 pubmed publisher
|
| Liu J, Liu B, Chen S, Gong B, Chen L, Zhou Q, et al. A Tyrosine Phosphorylation Cycle Regulates Fungal Activation of a Plant Receptor Ser/Thr Kinase. Cell Host Microbe. 2018;23:241-253.e6 pubmed publisher
|
| Youn J, Dunham W, Hong S, Knight J, Bashkurov M, Chen G, et al. High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Mol Cell. 2018;69:517-532.e11 pubmed publisher
|
| Zhang X, Cao J, Miller S, Jing H, Lin H. Comparative Nucleotide-Dependent Interactome Analysis Reveals Shared and Differential Properties of KRas4a and KRas4b. ACS Cent Sci. 2018;4:71-80 pubmed publisher
|
| Hsieh W, Hsu T, Chang Y, Lai M. IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells. Nat Commun. 2018;9:463 pubmed publisher
|
| Broughton S, Hercus T, Nero T, Kan W, Barry E, Dottore M, et al. A dual role for the N-terminal domain of the IL-3 receptor in cell signalling. Nat Commun. 2018;9:386 pubmed publisher
|
| Chukwurah E, Patel R. Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate cellular survival. Sci Rep. 2018;8:1020 pubmed publisher
|
| Khan O, Carvalho J, Spencer Dene B, Mitter R, Frith D, Snijders A, et al. The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer. J Clin Invest. 2018;128:1326-1337 pubmed publisher
|
| Chen X, Lu L, Qian S, Scalf M, Smith L, Zhong X. Canonical and Noncanonical Actions of Arabidopsis Histone Deacetylases in Ribosomal RNA Processing. Plant Cell. 2018;30:134-152 pubmed publisher
|
| Zhang Y, Harris C, Liu Q, Liu W, Ausin I, Long Y, et al. Large-scale comparative epigenomics reveals hierarchical regulation of non-CG methylation in Arabidopsis. Proc Natl Acad Sci U S A. 2018;115:E1069-E1074 pubmed publisher
|
| Vantourout P, Laing A, Woodward M, Zlatareva I, Apolonia L, Jones A, et al. Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing ?? T cell biology. Proc Natl Acad Sci U S A. 2018;115:1039-1044 pubmed publisher
|
| Gardner B, Castanzo D, Chowdhury S, Stjepanovic G, Stefely M, Hurley J, et al. The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading. Nat Commun. 2018;9:135 pubmed publisher
|
| Hasegawa Y, Ikeda K, Chen Y, Alba D, Stifler D, Shinoda K, et al. Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis. Cell Metab. 2018;27:180-194.e6 pubmed publisher
|
| Yan T, Ooi W, Qamra A, Cheung A, Ma D, Sundaram G, et al. HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis. Nat Commun. 2018;9:100 pubmed publisher
|
| Cho H, Kim J, Lee S, Hwang Y, Park S, Kim B, et al. Protein phosphatase 1B dephosphorylates Rho guanine nucleotide dissociation inhibitor 1 and suppresses cancer cell migration and invasion. Cancer Lett. 2018;417:141-151 pubmed publisher
|
| Zhou X, Dong S, Liu Z, Liu S, Zhang C, Liang X. Regulation of gammaherpesvirus lytic replication by endoplasmic reticulum stress-induced transcription factors ATF4 and CHOP. J Biol Chem. 2018;293:2801-2814 pubmed publisher
|
| Maddalena A, Tornabene P, Tiberi P, Minopoli R, Manfredi A, Mutarelli M, et al. Triple Vectors Expand AAV Transfer Capacity in the Retina. Mol Ther. 2018;26:524-541 pubmed publisher
|
| Du Y, Duan T, Feng Y, Liu Q, Lin M, Cui J, et al. LRRC25 inhibits type I IFN signaling by targeting ISG15-associated RIG-I for autophagic degradation. EMBO J. 2018;37:351-366 pubmed publisher
|
| Holze C, Michaudel C, Mackowiak C, Haas D, Benda C, Hubel P, et al. Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway. Nat Immunol. 2018;19:130-140 pubmed publisher
|
| Chan Y, Fugger K, West S. Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations. Nat Cell Biol. 2018;20:92-103 pubmed publisher
|
| Zhao Q, Buhr D, Gunter C, Frenette J, Ferguson M, Sanford E, et al. Rational library design by functional CDR resampling. N Biotechnol. 2018;45:89-97 pubmed publisher
|
| Jakka P, Bhargavi B, Namani S, Murugan S, Splitter G, Radhakrishnan G. Cytoplasmic Linker Protein CLIP170 Negatively Regulates TLR4 Signaling by Targeting the TLR Adaptor Protein TIRAP. J Immunol. 2018;200:704-714 pubmed publisher
|
| Yen J, Wei L, Chen L, Chen L, Hung C, Wang S, et al. Subcellular Localization and Functional Characterization of GII.4 Norovirus-Encoded NTPase. J Virol. 2018;92: pubmed publisher
|
| Abbas H, Bui N, Rajapakshe K, Wong J, Gunaratne P, Tsai K, et al. Distinct TP63 Isoform-Driven Transcriptional Signatures Predict Tumor Progression and Clinical Outcomes. Cancer Res. 2018;78:451-462 pubmed publisher
|
| Cummins T, Wu K, Bozatzi P, Dingwell K, MacArtney T, Wood N, et al. PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP. J Cell Sci. 2018;131: pubmed publisher
|
| McGinnis J, Kay B. Generation of recombinant affinity reagents against a two-phosphosite epitope of ATF2. N Biotechnol. 2018;45:45-50 pubmed publisher
|
| Cho H, Hwang Y, Yoon J, Lee M, Lee H, Daar I. EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1. Oncogene. 2018;37:861-872 pubmed publisher
|
| Huang H, Gehan M, Huss S, Alvarez S, Lizárraga C, Gruebbling E, et al. Cross-species complementation reveals conserved functions for EARLY FLOWERING 3 between monocots and dicots. Plant Direct. 2017;1:e00018 pubmed publisher
|
| Xu T, Yan Y, Harikumar K, Miller L, Melcher K, Xu H. Streptavidin Bead Pulldown Assay to Determine Protein Homooligomerization. Bio Protoc. 2017;7: pubmed publisher
|
| Bleuyard J, Butler R, Esashi F. Perturbation of PALB2 function by the T413S mutation found in small cell lung cancer. Wellcome Open Res. 2017;2:110 pubmed publisher
|
| Bürger M, Willige B, Chory J. A hydrophobic anchor mechanism defines a deacetylase family that suppresses host response against YopJ effectors. Nat Commun. 2017;8:2201 pubmed publisher
|
| Tobita T, Nomura S, Morita H, Ko T, Fujita T, Toko H, et al. Identification of MYLK3 mutations in familial dilated cardiomyopathy. Sci Rep. 2017;7:17495 pubmed publisher
|
| Huang J, Gu L, Zhang Y, Yan T, Kong G, Kong L, et al. An oomycete plant pathogen reprograms host pre-mRNA splicing to subvert immunity. Nat Commun. 2017;8:2051 pubmed publisher
|
| Li D, Liu S, Zhu L, Wang Y, Chen Y, Liu J, et al. FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death. Oncotarget. 2017;8:97178-97186 pubmed publisher
|
| Weintraub A, Li C, Zamudio A, Sigova A, Hannett N, Day D, et al. YY1 Is a Structural Regulator of Enhancer-Promoter Loops. Cell. 2017;171:1573-1588.e28 pubmed publisher
|
| Wu C, Su Z, Lin M, Ou J, Zhao W, Cui J, et al. NLRP11 attenuates Toll-like receptor signalling by targeting TRAF6 for degradation via the ubiquitin ligase RNF19A. Nat Commun. 2017;8:1977 pubmed publisher
|
| Long Y, Bolaños B, Gong L, Liu W, Goodrich K, Yang X, et al. Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2. elife. 2017;6: pubmed publisher
|
| Ranaghan M, Durney M, Mesleh M, McCarren P, Garvie C, Daniels D, et al. The Autophagy-related Beclin-1 Protein requires both the Coiled-coil and BARA Domains to form a Homodimer with Sub-micromolar affinity. Biochemistry. 2017;: pubmed publisher
|
| Chen H, Chen J, Li M, Chang M, Xu K, Shang Z, et al. A Bacterial Type III Effector Targets the Master Regulator of Salicylic Acid Signaling, NPR1, to Subvert Plant Immunity. Cell Host Microbe. 2017;22:777-788.e7 pubmed publisher
|
| Klisch T, Vainshtein A, Patel A, Zoghbi H. Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth. elife. 2017;6: pubmed publisher
|
| de Pablo Maiso L, Glaria I, Crespo H, Nistal Villán E, Andresdottir V, de Andrés D, et al. Characterization of Ovine A3Z1 Restriction Properties against Small Ruminant Lentiviruses (SRLVs). Viruses. 2017;9: pubmed publisher
|
| Phan A, Vo V, Hua T, Kim M, Jo S, Choi J, et al. PPAR? sumoylation-mediated lipid accumulation in lung cancer. Oncotarget. 2017;8:82491-82505 pubmed publisher
|
| Reitsma J, Liu X, Reichermeier K, Moradian A, Sweredoski M, Hess S, et al. Composition and Regulation of the Cellular Repertoire of SCF Ubiquitin Ligases. Cell. 2017;171:1326-1339.e14 pubmed publisher
|
| Hiyama A, Takemiya A, Munemasa S, Okuma E, Sugiyama N, Tada Y, et al. Blue light and CO2 signals converge to regulate light-induced stomatal opening. Nat Commun. 2017;8:1284 pubmed publisher
|
| Qin Y, Su Z, Wu Y, Wu C, Jin S, Xie W, et al. NLRP11 disrupts MAVS signalosome to inhibit type I interferon signaling and virus-induced apoptosis. EMBO Rep. 2017;18:2160-2171 pubmed publisher
|
| Sprenger H, Kienesberger S, Pertschy B, Pöltl L, Konrad B, Bhutada P, et al. Fic Proteins of Campylobacter fetus subsp. venerealis Form a Network of Functional Toxin-Antitoxin Systems. Front Microbiol. 2017;8:1965 pubmed publisher
|
| Lee D, Park S, Ahn C, Pai H. MRF Family Genes Are Involved in Translation Control, Especially under Energy-Deficient Conditions, and Their Expression and Functions Are Modulated by the TOR Signaling Pathway. Plant Cell. 2017;29:2895-2920 pubmed publisher
|
| Xie J, Bohovych I, Wong E, Lambert J, Gingras A, Khalimonchuk O, et al. Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2. Microb Cell. 2017;4:342-361 pubmed publisher
|
| Gessaman J, Selker E. Induction of H3K9me3 and DNA methylation by tethered heterochromatin factors in Neurospora crassa. Proc Natl Acad Sci U S A. 2017;114:E9598-E9607 pubmed publisher
|
| Krendl C, Shaposhnikov D, Rishko V, Ori C, Ziegenhain C, Sass S, et al. GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency. Proc Natl Acad Sci U S A. 2017;114:E9579-E9588 pubmed publisher
|
| Tao Z, Shen L, Gu X, Wang Y, Yu H, He Y. Embryonic epigenetic reprogramming by a pioneer transcription factor in plants. Nature. 2017;551:124-128 pubmed publisher
|
| Jakka P, Namani S, Murugan S, Rai N, Radhakrishnan G. The Brucella effector protein TcpB induces degradation of inflammatory caspases and thereby subverts non-canonical inflammasome activation in macrophages. J Biol Chem. 2017;292:20613-20627 pubmed publisher
|
| Gabrielsen M, Buetow L, Nakasone M, Ahmed S, Sibbet G, Smith B, et al. A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants. Mol Cell. 2017;68:456-470.e10 pubmed publisher
|
| Tan P, He L, Cui J, Qian C, Cao X, Lin M, et al. Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling. Mol Cell. 2017;68:293-307.e5 pubmed publisher
|
| Bhattacharya S, Reddy D, Jani V, Gadewal N, Shah S, Reddy R, et al. Histone isoform H2A1H promotes attainment of distinct physiological states by altering chromatin dynamics. Epigenetics Chromatin. 2017;10:48 pubmed publisher
|
| Schmitzberger F, Richter M, Gordiyenko Y, Robinson C, Dadlez M, Westermann S. Molecular basis for inner kinetochore configuration through RWD domain-peptide interactions. EMBO J. 2017;36:3458-3482 pubmed publisher
|
| Kategaya L, Di Lello P, Rouge L, Pastor R, Clark K, Drummond J, et al. USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature. 2017;550:534-538 pubmed publisher
|
| Feng Y, Duan T, Du Y, Jin S, Wang M, Cui J, et al. LRRC25 Functions as an Inhibitor of NF-κB Signaling Pathway by Promoting p65/RelA for Autophagic Degradation. Sci Rep. 2017;7:13448 pubmed publisher
|
| Mao A, Ishizuka I, Kasal D, Mandal M, Bendelac A. A shared Runx1-bound Zbtb16 enhancer directs innate and innate-like lymphoid lineage development. Nat Commun. 2017;8:863 pubmed publisher
|
| Poleshko A, Shah P, Gupta M, Babu A, Morley M, Manderfield L, et al. Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction. Cell. 2017;171:573-587.e14 pubmed publisher
|
| Palmer C, Bruckner R, Paulo J, Kazak L, Long J, Mina A, et al. Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue. Mol Metab. 2017;6:1212-1225 pubmed publisher
|
| Haylock A, Nilvebrant J, Mortensen A, Velikyan I, Nestor M, Falk R. Generation and evaluation of antibody agents for molecular imaging of CD44v6-expressing cancers. Oncotarget. 2017;8:65152-65170 pubmed publisher
|
| Chen L, Yan Z, Xia Z, Cheng Y, Jiao Z, Sun B, et al. A Violaxanthin Deepoxidase Interacts with a Viral Suppressor of RNA Silencing to Inhibit Virus Amplification. Plant Physiol. 2017;175:1774-1794 pubmed publisher
|
| Tamahara T, Ochiai K, Muto A, Kato Y, Sax N, Matsumoto M, et al. The mTOR-Bach2 Cascade Controls Cell Cycle and Class Switch Recombination during B Cell Differentiation. Mol Cell Biol. 2017;37: pubmed publisher
|
| Kawaguchi T, Machida S, Kurumizaka H, Tagami H, Nakayama J. Phosphorylation of CBX2 controls its nucleosome-binding specificity. J Biochem. 2017;162:343-355 pubmed publisher
|
| Wang T, Wang B, Huang H, Zhang C, Zhu Y, Pei B, et al. Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication. PLoS Pathog. 2017;13:e1006674 pubmed publisher
|
| Roundtree I, Luo G, Zhang Z, Wang X, Zhou T, Cui Y, et al. YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. elife. 2017;6: pubmed publisher
|
| Yang C, Li J, Yu L, Zhang Z, Xu F, Jiang L, et al. Regulation of RIP3 by the transcription factor Sp1 and the epigenetic regulator UHRF1 modulates cancer cell necroptosis. Cell Death Dis. 2017;8:e3084 pubmed publisher
|
| Zhao W, Steinfeld J, Liang F, Chen X, Maranon D, Jian Ma C, et al. BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing. Nature. 2017;550:360-365 pubmed publisher
|
| Kanai S, Edwards A, Rurik J, Osei Owusu P, Blumer K. Proteolytic degradation of regulator of G protein signaling 2 facilitates temporal regulation of Gq/11 signaling and vascular contraction. J Biol Chem. 2017;292:19266-19278 pubmed publisher
|
| Sun L, Jiang Z, Acosta Rodriguez V, Berger M, Du X, Choi J, et al. HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections. J Exp Med. 2017;214:3263-3277 pubmed publisher
|
| Jin S, Tian S, Luo M, Xie W, Liu T, Duan T, et al. Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells. Mol Cell. 2017;68:308-322.e4 pubmed publisher
|
| Xian H, Xie W, Yang S, Liu Q, Xia X, Jin S, et al. Stratified ubiquitination of RIG-I creates robust immune response and induces selective gene expression. Sci Adv. 2017;3:e1701764 pubmed publisher
|
| Hinshaw S, Makrantoni V, Harrison S, Marston A. The Kinetochore Receptor for the Cohesin Loading Complex. Cell. 2017;171:72-84.e13 pubmed publisher
|
| Joris M, Schloesser M, Baurain D, Hanikenne M, Muller M, Motte P. Number of inadvertent RNA targets for morpholino knockdown in Danio rerio is largely underestimated: evidence from the study of Ser/Arg-rich splicing factors. Nucleic Acids Res. 2017;45:9547-9557 pubmed publisher
|
| Kaufmann T, Grishkovskaya I, Polyansky A, Kostrhon S, Kukolj E, Olek K, et al. A novel non-canonical PIP-box mediates PARG interaction with PCNA. Nucleic Acids Res. 2017;45:9741-9759 pubmed publisher
|
| Ghosh S, Wallerath C, Covarrubias S, Hornung V, Carpenter S, Fitzgerald K. The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression. J Immunol. 2017;199:3249-3260 pubmed publisher
|
| Takahama M, Fukuda M, Ohbayashi N, Kozaki T, Misawa T, Okamoto T, et al. The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses. Cell Rep. 2017;20:2944-2954 pubmed publisher
|
| Dondelinger Y, Delanghe T, Rojas Rivera D, Priem D, Delvaeye T, Bruggeman I, et al. MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death. Nat Cell Biol. 2017;19:1237-1247 pubmed publisher
|
| Diaz J, Morgan C, Minogue C, Hebert A, Coon J, Wells J. A Split-Abl Kinase for Direct Activation in Cells. Cell Chem Biol. 2017;24:1250-1258.e4 pubmed publisher
|
| Armour S, Remsberg J, Damle M, Sidoli S, Ho W, Li Z, et al. An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides. Nat Commun. 2017;8:549 pubmed publisher
|
| Zu T, Cleary J, Liu Y, Bañez Coronel M, Bubenik J, Ayhan F, et al. RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2. Neuron. 2017;95:1292-1305.e5 pubmed publisher
|
| Kanayama M, Hayano T, Koebis M, Maeda T, Tabe Y, Horie S, et al. Hyperactive mTOR induces neuroendocrine differentiation in prostate cancer cell with concurrent up-regulation of IRF1. Prostate. 2017;77:1489-1498 pubmed publisher
|
| Kunde S, Rademacher N, Zieger H, Shoichet S. Protein kinase C regulates AMPA receptor auxiliary protein Shisa9/CKAMP44 through interactions with neuronal scaffold PICK1. FEBS Open Bio. 2017;7:1234-1245 pubmed publisher
|
| Choi E, Cheon Y, Kang K, Lee D. The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3. Nat Commun. 2017;8:529 pubmed publisher
|
| Hutt M, Marquardt L, Seifert O, Siegemund M, Muller I, Kulms D, et al. Superior Properties of Fc-comprising scTRAIL Fusion Proteins. Mol Cancer Ther. 2017;16:2792-2802 pubmed publisher
|
| Purcell R, Toro C, Gahl W, Hall R. A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2) increases receptor signaling activity. Hum Mutat. 2017;38:1751-1760 pubmed publisher
|
| Mo Y, Lin R, Liu P, Tan M, Xiong Y, Guan K, et al. SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes. FEBS J. 2017;284:3619-3636 pubmed publisher
|
| He R, Peng J, Yuan P, Yang J, Wu X, Wang Y, et al. Glucosyltransferase Activity of Clostridium difficile Toxin B Triggers Autophagy-mediated Cell Growth Arrest. Sci Rep. 2017;7:10532 pubmed publisher
|
| Papizan J, Garry G, Brezprozvannaya S, McAnally J, Bassel Duby R, Liu N, et al. Deficiency in Kelch protein Klhl31 causes congenital myopathy in mice. J Clin Invest. 2017;127:3730-3740 pubmed publisher
|
| Chen S, Zhu B, Yin C, Liu W, Han C, Chen B, et al. Palmitoylation-dependent activation of MC1R prevents melanomagenesis. Nature. 2017;549:399-403 pubmed publisher
|
| Martini T, Stojan J, Rozman D, Prosenc Zmrzljak U. Interaction of PER2 with the Constitutive Androstane Receptor Possibly Links Circadian Rhythms to Metabolism. Acta Chim Slov. 2017;64:571-576 pubmed
|
| Zhang Y, Ku W, Liu S, Cui K, Jin W, Tang Q, et al. Genome-wide identification of histone H2A and histone variant H2A.Z-interacting proteins by bPPI-seq. Cell Res. 2017;27:1258-1274 pubmed publisher
|
| Lee S, Nam T, Li W, Kim J, Yoon W, Choi Y, et al. Functional validation of novel MKS3/TMEM67 mutations in COACH syndrome. Sci Rep. 2017;7:10222 pubmed publisher
|
| Entzminger K, Hyun J, Pantazes R, Patterson Orazem A, Qerqez A, Frye Z, et al. De novo design of antibody complementarity determining regions binding a FLAG tetra-peptide. Sci Rep. 2017;7:10295 pubmed publisher
|
| Scott N, Giogha C, Pollock G, Kennedy C, Webb A, Williamson N, et al. The bacterial arginine glycosyltransferase effector NleB preferentially modifies Fas-associated death domain protein (FADD). J Biol Chem. 2017;292:17337-17350 pubmed publisher
|
| Heidenreich S, Witte N, WEBER P, Goehring I, Tolkachov A, von Loeffelholz C, et al. Retinol saturase coordinates liver metabolism by regulating ChREBP activity. Nat Commun. 2017;8:384 pubmed publisher
|
| Gong Y, Guy C, Crawford J, Green D. Biological events and molecular signaling following MLKL activation during necroptosis. Cell Cycle. 2017;16:1748-1760 pubmed publisher
|
| Zhu M, Jiang L, Bai B, Zhao W, Chen X, Li J, et al. The Intracellular Immune Receptor Sw-5b Confers Broad-Spectrum Resistance to Tospoviruses through Recognition of a Conserved 21-Amino Acid Viral Effector Epitope. Plant Cell. 2017;29:2214-2232 pubmed publisher
|
| Hsu P, Zhu Y, Ma H, Guo Y, Shi X, Liu Y, et al. Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis. Cell Res. 2017;27:1115-1127 pubmed publisher
|
| Karabadzhak A, Petti L, Barrera F, Edwards A, Moya Rodríguez A, Polikanov Y, et al. Two transmembrane dimers of the bovine papillomavirus E5 oncoprotein clamp the PDGF ? receptor in an active dimeric conformation. Proc Natl Acad Sci U S A. 2017;114:E7262-E7271 pubmed publisher
|
| Jain P, Fierst T, Han H, Smith T, Vakil A, Storm P, et al. CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles. Oncogene. 2017;36:6348-6358 pubmed publisher
|
| Lu F, Wiedmer A, Martin K, Wickramasinghe P, Kossenkov A, Lieberman P. Coordinate Regulation of TET2 and EBNA2 Controls the DNA Methylation State of Latent Epstein-Barr Virus. J Virol. 2017;91: pubmed publisher
|
| Oda S, Numaga Tomita T, Kitajima N, Toyama T, Harada E, Shimauchi T, et al. TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice. Sci Rep. 2017;7:7511 pubmed publisher
|
| Yan Y, Xu T, Harikumar K, Miller L, Melcher K, Xu H. Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the ?-secretase cleavage sites. J Biol Chem. 2017;292:15826-15837 pubmed publisher
|
| Seidel L, Zarzycka B, Zaidi S, KATRITCH V, Coin I. Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells. elife. 2017;6: pubmed publisher
|
| Shirai A, Kawaguchi T, Shimojo H, Muramatsu D, Ishida Yonetani M, Nishimura Y, et al. Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly. elife. 2017;6: pubmed publisher
|
| Srivastava S, Mohibi S, Mirza S, Band H, Band V. Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway. Cell Cycle. 2017;16:1515-1525 pubmed publisher
|
| Lin K, Moroishi T, Meng Z, Jeong H, Plouffe S, Sekido Y, et al. Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation. Nat Cell Biol. 2017;19:996-1002 pubmed publisher
|
| Redwine W, Desantis M, Hollyer I, Htet Z, Tran P, Swanson S, et al. The human cytoplasmic dynein interactome reveals novel activators of motility. elife. 2017;6: pubmed publisher
|
| Guan W, Guyot R, Samarut J, Flamant F, Wong J, Gauthier K. Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin. Proc Natl Acad Sci U S A. 2017;114:8229-8234 pubmed publisher
|
| Miele E, Po A, Begalli F, Antonucci L, Mastronuzzi A, Marras C, et al. β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells. BMC Cancer. 2017;17:488 pubmed publisher
|
| Deakyne J, Malecka K, Messick T, Lieberman P. Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance. J Virol. 2017;91: pubmed publisher
|
| Chang P, Chen L, Chen L, Hung C, Shih Y, Wang S. Effects of the NEDD8-Activating Enzyme Inhibitor MLN4924 on Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2017;91: pubmed publisher
|
| Yuen K, Slaughter B, Gerton J. Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters. Sci Adv. 2017;3:e1700191 pubmed publisher
|
| Jih G, Iglesias N, Currie M, Bhanu N, Paulo J, Gygi S, et al. Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription. Nature. 2017;547:463-467 pubmed publisher
|
| Kishor A, White E, Matsangos A, Yan Z, Tandukar B, Wilson G. Hsp70's RNA-binding and mRNA-stabilizing activities are independent of its protein chaperone functions. J Biol Chem. 2017;292:14122-14133 pubmed publisher
|
| Parrell D, Zhang Y, Olenic S, Kroos L. Bacillus subtilis Intramembrane Protease RasP Activity in Escherichia coli and In Vitro. J Bacteriol. 2017;199: pubmed publisher
|
| Martens S, Jeong M, Tonnus W, Feldmann F, Hofmans S, Goossens V, et al. Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury. Cell Death Dis. 2017;8:e2904 pubmed publisher
|
| Gao Y, Wu Z, Xie L, Li C, Mao Y, Duan Y, et al. VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2. Nat Commun. 2017;8:15337 pubmed publisher
|
| Chaudhari S, Li W, Wang Y, Jiang H, Ma Y, Davis M, et al. Store-operated calcium entry suppressed the TGF-β1/Smad3 signaling pathway in glomerular mesangial cells. Am J Physiol Renal Physiol. 2017;313:F729-F739 pubmed publisher
|
| Kubota A, Ito S, Shim J, Johnson R, Song Y, Breton G, et al. TCP4-dependent induction of CONSTANS transcription requires GIGANTEA in photoperiodic flowering in Arabidopsis. PLoS Genet. 2017;13:e1006856 pubmed publisher
|
| Ivanov A, Gonzalez Pecchi V, Khuri L, Niu Q, Wang Y, Xu Y, et al. OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc. Oncogene. 2017;36:5852-5860 pubmed publisher
|
| Brahma S, Udugama M, Kim J, Hada A, Bhardwaj S, Hailu S, et al. INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers. Nat Commun. 2017;8:15616 pubmed publisher
|
| Park J, Park Y, Ryu I, Choi M, Lee H, Oh N, et al. Misfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complex. Nat Commun. 2017;8:15730 pubmed publisher
|
| Zhang W, Sartori M, Makhnevych T, Federowicz K, Dong X, Liu L, et al. Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10. J Mol Biol. 2017;429:3546-3560 pubmed publisher
|
| Wang J, Tian C, Zhang C, Shi B, Cao X, Zhang T, et al. Cytokinin Signaling Activates WUSCHEL Expression during Axillary Meristem Initiation. Plant Cell. 2017;29:1373-1387 pubmed publisher
|
| Hurley A, Bassler B. Asymmetric regulation of quorum-sensing receptors drives autoinducer-specific gene expression programs in Vibrio cholerae. PLoS Genet. 2017;13:e1006826 pubmed publisher
|
| Zhang J, Zhang C, Cui J, Ou J, Han J, Qin Y, et al. TRIM45 functions as a tumor suppressor in the brain via its E3 ligase activity by stabilizing p53 through K63-linked ubiquitination. Cell Death Dis. 2017;8:e2831 pubmed publisher
|
| Yonezawa T, Takahashi H, Shikata S, Liu X, Tamura M, Asada S, et al. The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1. J Biol Chem. 2017;292:12528-12541 pubmed publisher
|
| Good C, Madzo J, Patel B, Maegawa S, Engel N, Jelinek J, et al. A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer. Nucleic Acids Res. 2017;45:8269-8281 pubmed publisher
|
| Tsuchiya H, Ohtake F, Arai N, Kaiho A, Yasuda S, Tanaka K, et al. In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome. Mol Cell. 2017;66:488-502.e7 pubmed publisher
|
| Sun J, Yu S, Zhang X, Capac C, Aligbe O, Daudelin T, et al. A Wntless-SEC12 complex on the ER membrane regulates early Wnt secretory vesicle assembly and mature ligand export. J Cell Sci. 2017;130:2159-2171 pubmed publisher
|
| Kanuma T, Yamamoto T, Kobiyama K, Moriishi E, Masuta Y, Kusakabe T, et al. CD63-Mediated Antigen Delivery into Extracellular Vesicles via DNA Vaccination Results in Robust CD8+ T Cell Responses. J Immunol. 2017;198:4707-4715 pubmed publisher
|
| Ni W, Xu S, González Grandío E, Chalkley R, Huhmer A, Burlingame A, et al. PPKs mediate direct signal transfer from phytochrome photoreceptors to transcription factor PIF3. Nat Commun. 2017;8:15236 pubmed publisher
|
| Fulcher L, Hutchinson L, MacArtney T, Turnbull C, Sapkota G. Targeting endogenous proteins for degradation through the affinity-directed protein missile system. Open Biol. 2017;7: pubmed publisher
|
| Liu K, Niu Y, Konishi M, Wu Y, Du H, Sun Chung H, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature. 2017;545:311-316 pubmed publisher
|
| Bisht K, Grill S, Graniel J, Nandakumar J. A lentivirus-free inducible CRISPR-Cas9 system for efficient targeting of human genes. Anal Biochem. 2017;530:40-49 pubmed publisher
|
| Rialdi A, Hultquist J, Jimenez Morales D, Peralta Z, Campisi L, Fenouil R, et al. The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity. Cell. 2017;169:679-692.e14 pubmed publisher
|
| Bartel C, Jackson M. HER2-positive breast cancer cells expressing elevated FAM83A are sensitive to FAM83A loss. PLoS ONE. 2017;12:e0176778 pubmed publisher
|
| Lee B, Lee J, Shen W, Rhee C, Chung H, Kim J. Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B mono-ubiquitination. Nucleic Acids Res. 2017;45:7151-7166 pubmed publisher
|
| Frank R, Zhu F, Komiyama N, Grant S. Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes. J Neurochem. 2017;142:504-511 pubmed publisher
|
| Maguire C, Song Y, Wu M, Leon S, Carroll R, Alreja M, et al. Tac1 Signaling Is Required for Sexual Maturation and Responsiveness of GnRH Neurons to Kisspeptin in the Male Mouse. Endocrinology. 2017;158:2319-2329 pubmed publisher
|
| Geng C, Kaochar S, Li M, Rajapakshe K, Fiskus W, Dong J, et al. SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein. Oncogene. 2017;36:4767-4777 pubmed publisher
|
| Yan Y, Xu T, Melcher K, Xu H. Defining the minimum substrate and charge recognition model of gamma-secretase. Acta Pharmacol Sin. 2017;38:1412-1424 pubmed publisher
|
| Zhang X, Spiegelman N, Nelson O, Jing H, Lin H. SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation. elife. 2017;6: pubmed publisher
|
| Gong Y, Guy C, Olauson H, Becker J, Yang M, Fitzgerald P, et al. ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences. Cell. 2017;169:286-300.e16 pubmed publisher
|
| Oguchi M, Noguchi K, Fukuda M. TBC1D12 is a novel Rab11-binding protein that modulates neurite outgrowth of PC12 cells. PLoS ONE. 2017;12:e0174883 pubmed publisher
|
| Wu Y, Liu Q, Zhou J, Xie W, Chen C, Wang Z, et al. Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro. Cell Discov. 2017;3:17006 pubmed publisher
|
| Lopez C, Singh S, Hambarde S, Griffin W, Gao J, Chib S, et al. Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA. Nucleic Acids Res. 2017;45:5850-5862 pubmed publisher
|
| Wittmann S, Renner M, Watts B, Adams O, Huseyin M, Baejen C, et al. The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nat Commun. 2017;8:14861 pubmed publisher
|
| Huang C, Jiang Y, Zhou J, Yan Q, Jiang R, Cheng X, et al. Increased Krüppel-like factor 12 in recurrent implantation failure impairs endometrial decidualization by repressing Nur77 expression. Reprod Biol Endocrinol. 2017;15:25 pubmed publisher
|
| Aktas T, Avşar Ilık İ, Maticzka D, Bhardwaj V, Pessoa Rodrigues C, Mittler G, et al. DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. Nature. 2017;544:115-119 pubmed publisher
|
| Qi H, Xia F, Xie L, Yu L, Chen Q, Zhuang X, et al. TRAF Family Proteins Regulate Autophagy Dynamics by Modulating AUTOPHAGY PROTEIN6 Stability in Arabidopsis. Plant Cell. 2017;29:890-911 pubmed publisher
|
| Schalk C, Cognat V, Graindorge S, Vincent T, Voinnet O, Molinier J. Small RNA-mediated repair of UV-induced DNA lesions by the DNA DAMAGE-BINDING PROTEIN 2 and ARGONAUTE 1. Proc Natl Acad Sci U S A. 2017;114:E2965-E2974 pubmed publisher
|
| Kang H, Park J, Choi K, Choi H, Jung C, Kim G, et al. Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome. Aging Cell. 2017;16:541-550 pubmed publisher
|
| Wang X, Goodrich K, Gooding A, Naeem H, Archer S, Paucek R, et al. Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines. Mol Cell. 2017;65:1056-1067.e5 pubmed publisher
|
| van Haaften Visser D, Harakalová M, Mocholí E, van Montfrans J, Elkadri A, Rieter E, et al. Ankyrin repeat and zinc-finger domain-containing 1 mutations are associated with infantile-onset inflammatory bowel disease. J Biol Chem. 2017;292:7904-7920 pubmed publisher
|
| Haick J, Brueggemann L, Cribbs L, Denning M, Schwartz J, Byron K. PKC-dependent regulation of Kv7.5 channels by the bronchoconstrictor histamine in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2017;312:L822-L834 pubmed publisher
|
| Coni S, Mancuso A, Di Magno L, Sdruscia G, Manni S, Serrao S, et al. Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma. Sci Rep. 2017;7:44079 pubmed publisher
|
| Doiron K, Goyon V, Coyaud E, Rajapakse S, Raught B, McBride H. The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity. Sci Rep. 2017;7:107 pubmed publisher
|
| Teveroni E, Pellegrino M, Sacconi S, Calandra P, Cascino I, Farioli Vecchioli S, et al. Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity. J Clin Invest. 2017;127:1531-1545 pubmed publisher
|
| Zentella R, Sui N, Barnhill B, Hsieh W, Hu J, Shabanowitz J, et al. The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA. Nat Chem Biol. 2017;13:479-485 pubmed publisher
|
| Imagawa E, Higashimoto K, Sakai Y, Numakura C, Okamoto N, Matsunaga S, et al. Mutations in genes encoding polycomb repressive complex 2 subunits cause Weaver syndrome. Hum Mutat. 2017;38:637-648 pubmed publisher
|
| Kumari P, Srivastava A, Ghosh E, Ranjan R, Dogra S, Yadav P, et al. Core engagement with ?-arrestin is dispensable for agonist-induced vasopressin receptor endocytosis and ERK activation. Mol Biol Cell. 2017;28:1003-1010 pubmed publisher
|
| Li Z, Ivanov A, Su R, Gonzalez Pecchi V, Qi Q, Liu S, et al. The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nat Commun. 2017;8:14356 pubmed publisher
|
| Lu Y, Kwintkiewicz J, Liu Y, Tech K, Frady L, Su Y, et al. Chemosensitivity of IDH1-Mutated Gliomas Due to an Impairment in PARP1-Mediated DNA Repair. Cancer Res. 2017;77:1709-1718 pubmed publisher
|
| Aramsangtienchai P, Spiegelman N, Cao J, Lin H. S-Palmitoylation of Junctional Adhesion Molecule C Regulates Its Tight Junction Localization and Cell Migration. J Biol Chem. 2017;292:5325-5334 pubmed publisher
|
| Umstead M, Xiong J, Qi Q, Du Y, Fu H. Aurora kinase A interacts with H-Ras and potentiates Ras-MAPK signaling. Oncotarget. 2017;8:28359-28372 pubmed publisher
|
| Nyati K, Masuda K, Zaman M, Dubey P, Millrine D, Chalise J, et al. TLR4-induced NF-?B and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a. Nucleic Acids Res. 2017;45:2687-2703 pubmed publisher
|
| Goth C, Tuhkanen H, Khan H, Lackman J, Wang S, Narimatsu Y, et al. Site-specific O-Glycosylation by Polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage. J Biol Chem. 2017;292:4714-4726 pubmed publisher
|
| Xu T, Zhang H, Park S, Venneti S, Kuick R, Ha K, et al. Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis. Neoplasia. 2017;19:216-225 pubmed publisher
|
| Kim D, Choi J, Fan C, Shearer R, Sharif M, Busch P, et al. Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiation. Nucleic Acids Res. 2017;45:5112-5125 pubmed publisher
|
| Nounamo B, Li Y, O Byrne P, Kearney A, Khan A, Liu J. An interaction domain in human SAMD9 is essential for myxoma virus host-range determinant M062 antagonism of host anti-viral function. Virology. 2017;503:94-102 pubmed publisher
|
| Tang L, Heller M, Meng Z, Yu L, Tang Y, Zhou M, et al. Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway. J Biol Chem. 2017;292:4302-4312 pubmed publisher
|
| Hu Y, Li W, Gao T, Cui Y, Jin Y, Li P, et al. The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination. J Virol. 2017;91: pubmed publisher
|
| Aeschimann F, Kumari P, Bartake H, Gaidatzis D, Xu L, Ciosk R, et al. LIN41 Post-transcriptionally Silences mRNAs by Two Distinct and Position-Dependent Mechanisms. Mol Cell. 2017;65:476-489.e4 pubmed publisher
|
| Shi H, Wang X, Lu Z, Zhao B, Ma H, Hsu P, et al. YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA. Cell Res. 2017;27:315-328 pubmed publisher
|
| Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, et al. A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity. Nat Commun. 2017;8:14059 pubmed publisher
|
| Durzynska I, Xu X, Adelmant G, Ficarro S, Marto J, Sliz P, et al. STK40 Is a Pseudokinase that Binds the E3Â Ubiquitin Ligase COP1. Structure. 2017;25:287-294 pubmed publisher
|
| Upadhyay M, Agarwal S, Bhadauriya P, Ganesh S. Loss of laforin or malin results in increased Drp1 level and concomitant mitochondrial fragmentation in Lafora disease mouse models. Neurobiol Dis. 2017;100:39-51 pubmed publisher
|
| Skopková M, Hennig F, Shin B, Turner C, Stanikova D, Brennerova K, et al. EIF2S3 Mutations Associated with Severe X-Linked Intellectual Disability Syndrome MEHMO. Hum Mutat. 2017;38:409-425 pubmed publisher
|
| Mórocz M, Zsigmond E, Toth R, Enyedi M, Pintér L, Haracska L. DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA. Nucleic Acids Res. 2017;45:3172-3188 pubmed publisher
|
| Xi X, Lu L, Zhuge C, Chen X, Zhai Y, Cheng J, et al. The hypoparathyroidism-associated mutation in Drosophila Gcm compromises protein stability and glial cell formation. Sci Rep. 2017;7:39856 pubmed publisher
|
| Kinosada H, Yasunaga J, Shimura K, Miyazato P, Onishi C, Iyoda T, et al. HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors. PLoS Pathog. 2017;13:e1006120 pubmed publisher
|
| Takada M, Zhuang M, Inuzuka H, Zhang J, Zurlo G, Zhang J, et al. EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor. Oncotarget. 2017;8:6787-6795 pubmed publisher
|
| Sleven H, Welsh S, Yu J, Churchill M, Wright C, Henderson A, et al. De Novo Mutations in EBF3 Cause a Neurodevelopmental Syndrome. Am J Hum Genet. 2017;100:138-150 pubmed publisher
|
| Wei Y, Chiang W, Sumpter R, Mishra P, Levine B. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. Cell. 2017;168:224-238.e10 pubmed publisher
|
| Ben Khalifa Y, Luco S, Besson B, Sonthonnax F, Archambaud M, Grimes J, et al. The matrix protein of rabies virus binds to RelAp43 to modulate NF-κB-dependent gene expression related to innate immunity. Sci Rep. 2016;6:39420 pubmed publisher
|
| Fellermeier S, Beha N, Meyer J, Ring S, Bader S, Kontermann R, et al. Advancing targeted co-stimulation with antibody-fusion proteins by introducing TNF superfamily members in a single-chain format. Oncoimmunology. 2016;5:e1238540 pubmed publisher
|
| Wang Y, Wu Y, Yu B, Yin Z, Xia Y. EXTRA-LARGE G PROTEINs Interact with E3 Ligases PUB4 and PUB2 and Function in Cytokinin and Developmental Processes. Plant Physiol. 2017;173:1235-1246 pubmed publisher
|
| Urbanus M, Quaile A, Stogios P, Morar M, Rao C, Di Leo R, et al. Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol Syst Biol. 2016;12:893 pubmed publisher
|
| Seo D, Ahn M, Park K, Kim E, Kim W. The N-Terminal UND Motif of the Arabidopsis U-Box E3 Ligase PUB18 Is Critical for the Negative Regulation of ABA-Mediated Stomatal Movement and Determines Its Ubiquitination Specificity for Exocyst Subunit Exo70B1. Plant Cell. 2016;28:2952-2973 pubmed publisher
|
| Zhang J, Yang Z, Ou J, Xia X, Zhi F, Cui J. The F-box protein FBXL18 promotes glioma progression by promoting K63-linked ubiquitination of Akt. FEBS Lett. 2017;591:145-154 pubmed publisher
|
| Leung I, Jarvik N, Sidhu S. A Highly Diverse and Functional Naïve Ubiquitin Variant Library for Generation of Intracellular Affinity Reagents. J Mol Biol. 2017;429:115-127 pubmed publisher
|
| Ohle C, Tesorero R, Schermann G, Dobrev N, Sinning I, Fischer T. Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair. Cell. 2016;167:1001-1013.e7 pubmed publisher
|
| Mana G, Clapero F, Panieri E, Panero V, Böttcher R, Tseng H, et al. PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nat Commun. 2016;7:13546 pubmed publisher
|
| Kaufmann T, Kukolj E, Brachner A, Beltzung E, Bruno M, Kostrhon S, et al. SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation. J Cell Sci. 2016;129:4607-4621 pubmed
|
| Chen X, Lu L, Mayer K, Scalf M, Qian S, Lomax A, et al. POWERDRESS interacts with HISTONE DEACETYLASE 9 to promote aging in Arabidopsis. elife. 2016;5: pubmed publisher
|
| Gu P, Wang Y, Bisht K, Wu L, Kukova L, Smith E, et al. Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis. Oncogene. 2017;36:1939-1951 pubmed publisher
|
| Chen X, Duan L, Luo P, Hu G, Yu X, Liu J, et al. FBXO6-Mediated Ubiquitination and Degradation of Ero1L Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis. Cell Physiol Biochem. 2016;39:2501-2508 pubmed
|
| Dang F, Wu R, Wang P, Wu Y, Azam M, Xu Q, et al. Fasting and Feeding Signals Control the Oscillatory Expression of Angptl8 to Modulate Lipid Metabolism. Sci Rep. 2016;6:36926 pubmed publisher
|
| Kitajima N, Numaga Tomita T, Watanabe M, Kuroda T, Nishimura A, Miyano K, et al. TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling. Sci Rep. 2016;6:37001 pubmed publisher
|
| Kumari P, Srivastava A, Banerjee R, Ghosh E, Gupta P, Ranjan R, et al. Functional competence of a partially engaged GPCR-β-arrestin complex. Nat Commun. 2016;7:13416 pubmed publisher
|
| Hu J, Khodadadi Jamayran A, Mao M, Shah K, Yang Z, Nasim M, et al. AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors. Nat Commun. 2016;7:13347 pubmed publisher
|
| Bisht K, Smith E, Tesmer V, Nandakumar J. Structural and functional consequences of a disease mutation in the telomere protein TPP1. Proc Natl Acad Sci U S A. 2016;113:13021-13026 pubmed
|
| Leach M, Kim T, DiGregorio S, Collins C, Zhang Z, Duennwald M, et al. Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity. G3 (Bethesda). 2017;7:95-108 pubmed publisher
|
| Feng B, Ma S, Chen S, Zhu N, Zhang S, Yu B, et al. PARylation of the forkhead-associated domain protein DAWDLE regulates plant immunity. EMBO Rep. 2016;17:1799-1813 pubmed
|
| Griesche N, Schilling J, Weber S, Rohm M, Pesch V, Matthes F, et al. Regulation of mRNA Translation by MID1: A Common Mechanism of Expanded CAG Repeat RNAs. Front Cell Neurosci. 2016;10:226 pubmed
|
| Rademacher N, Schmerl B, Lardong J, Wahl M, Shoichet S. MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density. Sci Rep. 2016;6:35283 pubmed publisher
|
| Myers K, Barone G, Ganesh A, Staples C, Howard A, Beveridge R, et al. The bornavirus-derived human protein EBLN1 promotes efficient cell cycle transit, microtubule organisation and genome stability. Sci Rep. 2016;6:35548 pubmed publisher
|
| Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, et al. Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. Nat Commun. 2016;7:13130 pubmed publisher
|
| Chang T, Wang S, Chen L, Shih Y, Chang L, Liu S, et al. Regulation of the Abundance of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2. PLoS Pathog. 2016;12:e1005918 pubmed publisher
|
| Tezval H, Dubrowinskaja N, Peters I, Reese C, Serth K, Atschekzei F, et al. Tumor Specific Epigenetic Silencing of Corticotropin Releasing Hormone -Binding Protein in Renal Cell Carcinoma: Association of Hypermethylation and Metastasis. PLoS ONE. 2016;11:e0163873 pubmed publisher
|
| Calcagnì A, Kors L, Verschuren E, De Cegli R, Zampelli N, Nusco E, et al. Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling. elife. 2016;5: pubmed publisher
|
| Li J, Zhou C, Dong B, Zhong H, Chen S, Li Q, et al. Single domain antibody-based bispecific antibody induces potent specific anti-tumor activity. Cancer Biol Ther. 2016;17:1231-1239 pubmed publisher
|
| Ohashi Y, Soler N, García Ortegón M, Zhang L, Kirsten M, Perisic O, et al. Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex. Autophagy. 2016;12:2129-2144 pubmed
|
| Zhang Q, Jin R, Zhang X, Sheng J, Yu F, Tan R, et al. The putative oncotarget CSN5 controls a transcription-uncorrelated p53-mediated autophagy implicated in cancer cell survival under curcumin treatment. Oncotarget. 2016;7:69688-69702 pubmed publisher
|
| Xu T, Yan Y, Kang Y, Jiang Y, Melcher K, Xu H. Alzheimer's disease-associated mutations increase amyloid precursor protein resistance to γ-secretase cleavage and the Aβ42/Aβ40 ratio. Cell Discov. 2016;2:16026 pubmed publisher
|
| Huang H, Deng Z, Vladimirova O, Wiedmer A, Lu F, Lieberman P, et al. Structural basis underlying viral hijacking of a histone chaperone complex. Nat Commun. 2016;7:12707 pubmed publisher
|
| Dang F, Sun X, Ma X, Wu R, Zhang D, Chen Y, et al. Insulin post-transcriptionally modulates Bmal1 protein to affect the hepatic circadian clock. Nat Commun. 2016;7:12696 pubmed publisher
|
| de Jong M, Liu Z, Chen D, Alto N. Shigella flexneri suppresses NF-?B activation by inhibiting linear ubiquitin chain ligation. Nat Microbiol. 2016;1:16084 pubmed publisher
|
| Ernst R, Krogager T, Maywood E, Zanchi R, Beránek V, Elliott T, et al. Genetic code expansion in the mouse brain. Nat Chem Biol. 2016;12:776-778 pubmed publisher
|
| Du H, Zhao Y, He J, Zhang Y, Xi H, Liu M, et al. YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex. Nat Commun. 2016;7:12626 pubmed publisher
|
| Schalk C, Drevensek S, Kramdi A, Kassam M, Ahmed I, Cognat V, et al. DNA DAMAGE BINDING PROTEIN2 Shapes the DNA Methylation Landscape. Plant Cell. 2016;28:2043-2059 pubmed publisher
|
| Campbell C, Samavarchi Tehrani P, Barrios Rodiles M, Datti A, Gingras A, Wrana J. The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin. J Cell Sci. 2016;129:3396-411 pubmed publisher
|
| Liu T, Tang Q, Liu K, Xie W, Liu X, Wang H, et al. TRIM11 Suppresses AIM2 Inflammasome by Degrading AIM2 via p62-Dependent Selective Autophagy. Cell Rep. 2016;16:1988-2002 pubmed publisher
|
| Kubota Y, Nomura K, Katoh Y, Yamashita R, Kaneko K, Furuyama K. Novel Mechanisms for Heme-dependent Degradation of ALAS1 Protein as a Component of Negative Feedback Regulation of Heme Biosynthesis. J Biol Chem. 2016;291:20516-29 pubmed publisher
|
| Boyle P, Schwizer S, Hind S, Kraus C, De la Torre Diaz S, He B, et al. Detecting N-myristoylation and S-acylation of host and pathogen proteins in plants using click chemistry. Plant Methods. 2016;12:38 pubmed publisher
|
| Gruber C, Lang S, Rajendra V, Nuk M, Raffl S, Schildbach J, et al. Conjugative DNA Transfer Is Enhanced by Plasmid R1 Partitioning Proteins. Front Mol Biosci. 2016;3:32 pubmed publisher
|
| Gal J, Kuang L, Barnett K, Zhu B, Shissler S, Korotkov K, et al. ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics. Acta Neuropathol. 2016;132:563-76 pubmed publisher
|
| Hjerpe R, Bett J, Keuss M, Solovyova A, McWilliams T, Johnson C, et al. UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome. Cell. 2016;166:935-949 pubmed publisher
|
| Schmid Burgk J, Höning K, Ebert T, Hornung V. CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism. Nat Commun. 2016;7:12338 pubmed publisher
|
| Kamelgarn M, Chen J, Kuang L, Arenas A, Zhai J, Zhu H, et al. Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS. Biochim Biophys Acta. 2016;1862:2004-14 pubmed publisher
|
| Schreiber K, Bentham A, Williams S, Kobe B, Staskawicz B. Multiple Domain Associations within the Arabidopsis Immune Receptor RPP1 Regulate the Activation of Programmed Cell Death. PLoS Pathog. 2016;12:e1005769 pubmed publisher
|
| Miyazaki Y, Du X, Muramatsu S, Gomez C. An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. Sci Transl Med. 2016;8:347ra94 pubmed publisher
|
| Mohibi S, Srivastava S, Bele A, Mirza S, Band H, Band V. Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation. Mol Cell Biol. 2016;36:2487-502 pubmed publisher
|
| Guo H, Feng P, Chi W, Sun X, Xu X, Li Y, et al. Plastid-nucleus communication involves calcium-modulated MAPK signalling. Nat Commun. 2016;7:12173 pubmed publisher
|
| Ito S, Asakura M, Liao Y, Min K, Takahashi A, Shindo K, et al. Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy. J Am Heart Assoc. 2016;5: pubmed publisher
|
| Shao W, Zumer K, Fujinaga K, Peterlin B. FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator). J Biol Chem. 2016;291:17953-63 pubmed publisher
|
| Wang Z, Dang T, Liu T, Chen S, Li L, Huang S, et al. NEDD4L Protein Catalyzes Ubiquitination of PIK3CA Protein and Regulates PI3K-AKT Signaling. J Biol Chem. 2016;291:17467-77 pubmed publisher
|
| Yuan B, Cheng L, Gupta K, Chiang H, Gupta H, Sareddy G, et al. Tyrosine phosphorylation regulates ER? ubiquitination, protein turnover, and inhibition of breast cancer. Oncotarget. 2016;7:42585-42597 pubmed publisher
|
| Zhang X, Khan S, Jiang H, Antonyak M, Chen X, Spiegelman N, et al. Identifying the functional contribution of the defatty-acylase activity of SIRT6. Nat Chem Biol. 2016;12:614-20 pubmed publisher
|
| Quintana M, Parry T, He J, Yates C, Sidorova T, Murray K, et al. Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling. Am J Pathol. 2016;186:1989-2007 pubmed publisher
|
| Kuramoto K, Wang N, Fan Y, Zhang W, Schoenen F, Frankowski K, et al. Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy. 2016;12:1460-71 pubmed publisher
|
| Reguera J, Gerlach P, Rosenthal M, Gaudon S, Coscia F, Gunther S, et al. Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. PLoS Pathog. 2016;12:e1005636 pubmed publisher
|
| Zhao B, Shu C, Gao X, Sankaran B, Du F, Shelton C, et al. Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins. Proc Natl Acad Sci U S A. 2016;113:E3403-12 pubmed publisher
|
| Groth M, Moissiard G, Wirtz M, Wang H, Garcia Salinas C, Ramos Parra P, et al. MTHFD1 controls DNA methylation in Arabidopsis. Nat Commun. 2016;7:11640 pubmed publisher
|
| Atsumi G, Suzuki H, Miyashita Y, Choi S, Hisa Y, Rihei S, et al. P3N-PIPO, a Frameshift Product from the P3 Gene, Pleiotropically Determines the Virulence of Clover Yellow Vein Virus in both Resistant and Susceptible Peas. J Virol. 2016;90:7388-7404 pubmed publisher
|
| Pawar A, Meier J, Dasgupta A, Diwanji N, Deshpande N, Saxena K, et al. Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling. Cell Signal. 2016;28:1225-36 pubmed publisher
|
| Gilmore J, Sardiu M, Groppe B, Thornton J, Liu X, Dayebgadoh G, et al. WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage. PLoS ONE. 2016;11:e0155492 pubmed publisher
|
| Tuschl K, Meyer E, Valdivia L, Zhao N, Dadswell C, Abdul Sada A, et al. Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia. Nat Commun. 2016;7:11601 pubmed publisher
|
| Shimizu H, Miyazaki H, Ohsawa N, Shoji S, Ishizuka Katsura Y, Tosaki A, et al. Structure-based site-directed photo-crosslinking analyses of multimeric cell-adhesive interactions of voltage-gated sodium channel β subunits. Sci Rep. 2016;6:26618 pubmed publisher
|
| Huang F, Saraf A, Florens L, Kusch T, Swanson S, Szerszen L, et al. The Enok acetyltransferase complex interacts with Elg1 and negatively regulates PCNA unloading to promote the G1/S transition. Genes Dev. 2016;30:1198-210 pubmed publisher
|
| Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen T, Texier Y, et al. An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Nat Commun. 2016;7:11491 pubmed publisher
|
| Harris C, Husmann D, Liu W, Kasmi F, Wang H, Papikian A, et al. Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes. PLoS Genet. 2016;12:e1005998 pubmed publisher
|
| Homma Y, Fukuda M. Rabin8 regulates neurite outgrowth in both GEF activity-dependent and -independent manners. Mol Biol Cell. 2016;27:2107-18 pubmed publisher
|
| Bui H, Enis D, Robciuc M, Nurmi H, Cohen J, Chen M, et al. Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFD. J Clin Invest. 2016;126:2167-80 pubmed publisher
|
| Stepanova V, Jayaraman P, Zaitsev S, Lebedeva T, Bdeir K, Kershaw R, et al. Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression. J Biol Chem. 2016;291:15029-45 pubmed publisher
|
| Rialdi A, Campisi L, Zhao N, Lagda A, Pietzsch C, Ho J, et al. Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation. Science. 2016;352:aad7993 pubmed publisher
|
| Lin S, Choe J, Du P, Triboulet R, Gregory R. The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell. 2016;62:335-345 pubmed publisher
|
| Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher
|
| Seo J, Singh N, Ottesen E, Sivanesan S, Shishimorova M, Singh R. Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene. PLoS ONE. 2016;11:e0154390 pubmed publisher
|
| Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, et al. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016;7:11391 pubmed publisher
|
| Gouignard N, Maccarana M, Strate I, von Stedingk K, Malmstrom A, Pera E. Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin. Dis Model Mech. 2016;9:607-20 pubmed publisher
|
| Onyango D, Howard S, Neherin K, Yanez D, Stark J. Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res. 2016;44:5702-16 pubmed publisher
|
| Jiang H, Zhang X, Lin H. Lysine fatty acylation promotes lysosomal targeting of TNF-?. Sci Rep. 2016;6:24371 pubmed publisher
|
| Siegemund M, Seifert O, Zarani M, Džinić T, De Leo V, Göttsch D, et al. An optimized antibody-single-chain TRAIL fusion protein for cancer therapy. MAbs. 2016;8:879-91 pubmed publisher
|
| Breslin J, Daines D, Doggett T, Kurtz K, Souza Smith F, Zhang X, et al. Rnd3 as a Novel Target to Ameliorate Microvascular Leakage. J Am Heart Assoc. 2016;5:e003336 pubmed publisher
|
| Wang Z, Ji J, Peng D, Ma F, Cheng G, Qin F. Complex Regulation Pattern of IRF3 Activation Revealed by a Novel Dimerization Reporter System. J Immunol. 2016;196:4322-30 pubmed publisher
|
| ULJON S, Xu X, Durzynska I, Stein S, Adelmant G, Marto J, et al. Structural Basis for Substrate Selectivity of the E3 Ligase COP1. Structure. 2016;24:687-696 pubmed publisher
|
| Zhou Z, Tang A, Wong W, Bamezai S, Goddard L, Shenkar R, et al. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature. 2016;532:122-6 pubmed publisher
|
| Zhang Y, Liu J, Wang S, Luo X, Li Y, Lv Z, et al. The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners. Oncotarget. 2016;7:23740-56 pubmed publisher
|
| Chaudhuri D, Artiga D, Abiria S, Clapham D. Mitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transition. Proc Natl Acad Sci U S A. 2016;113:E1872-80 pubmed publisher
|
| Worley J, Pombo M, Zheng Y, Dunham D, Myers C, Fei Z, et al. A novel method of transcriptome interpretation reveals a quantitative suppressive effect on tomato immune signaling by two domains in a single pathogen effector protein. BMC Genomics. 2016;17:229 pubmed publisher
|
| Zhang Y, Halder S, Kerr R, Parrell D, Ruotolo B, Kroos L. Complex Formed between Intramembrane Metalloprotease SpoIVFB and Its Substrate, Pro-σK. J Biol Chem. 2016;291:10347-62 pubmed publisher
|
| Choi S, Gearhart M, Cui Z, Bosnakovski D, Kim M, Schennum N, et al. DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes. Nucleic Acids Res. 2016;44:5161-73 pubmed publisher
|
| Myers S, Peddada S, Chatterjee N, Friedrich T, Tomoda K, Krings G, et al. SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells. elife. 2016;5:e10647 pubmed publisher
|
| Naik E, Dixit V. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity. J Immunol. 2016;196:3438-51 pubmed publisher
|
| Huang W, Martin E, Burman B, Gonzalez M, Kleer C. The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells. Oncotarget. 2016;7:25180-93 pubmed publisher
|
| Lasek A, McPherson B, Trueman N, Burkard M. The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic Complementation. PLoS ONE. 2016;11:e0150225 pubmed publisher
|
| Qin Y, Liu Q, Tian S, Xie W, Cui J, Wang R. TRIM9 short isoform preferentially promotes DNA and RNA virus-induced production of type I interferon by recruiting GSK3? to TBK1. Cell Res. 2016;26:613-28 pubmed publisher
|
| Hirano S, Uemura T, Annoh H, Fujita N, Waguri S, Itoh T, et al. Differing susceptibility to autophagic degradation of two LC3-binding proteins: SQSTM1/p62 and TBC1D25/OATL1. Autophagy. 2016;12:312-26 pubmed publisher
|
| Svensson K, Long J, Jedrychowski M, Cohen P, Lo J, Serag S, et al. A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function. Cell Metab. 2016;23:454-66 pubmed publisher
|
| Franciosa G, Diluvio G, Gaudio F, Giuli M, Palermo R, Grazioli P, et al. Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression. Oncogene. 2016;35:4741-51 pubmed publisher
|
| Kellner N, Schwarz J, Sturm M, Fernandez Martinez J, Griesel S, Zhang W, et al. Developing genetic tools to exploit Chaetomium thermophilum for biochemical analyses of eukaryotic macromolecular assemblies. Sci Rep. 2016;6:20937 pubmed publisher
|
| Yun T, Yu K, Yang S, Cui Y, Wang Z, Ren H, et al. Acetylation of p53 Protein at Lysine 120 Up-regulates Apaf-1 Protein and Sensitizes the Mitochondrial Apoptotic Pathway. J Biol Chem. 2016;291:7386-95 pubmed publisher
|
| Di Magno L, Basile A, Coni S, Manni S, Sdruscia G, D Amico D, et al. The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint. Oncotarget. 2016;7:9538-49 pubmed publisher
|
| Mitterer V, Murat G, Réty S, Blaud M, Delbos L, Stanborough T, et al. Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation. Nat Commun. 2016;7:10336 pubmed publisher
|
| Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher
|
| Burkovics P, Dome L, Juhasz S, Altmannova V, Sebesta M, Pacesa M, et al. The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis. Nucleic Acids Res. 2016;44:3176-89 pubmed publisher
|
| Richter H, Katic I, Gut H, Großhans H. Structural basis and function of XRN2 binding by XTB domains. Nat Struct Mol Biol. 2016;23:164-71 pubmed publisher
|
| Venegas L, Pershad K, Bankole O, Shah N, Kay B. A comparison of phosphospecific affinity reagents reveals the utility of recombinant Forkhead-associated domains in recognizing phosphothreonine-containing peptides. N Biotechnol. 2016;33:537-43 pubmed publisher
|
| Aini H, Itaka K, Fujisawa A, Uchida H, Uchida S, Fukushima S, et al. Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment. Sci Rep. 2016;6:18743 pubmed publisher
|
| Skieterska K, Rondou P, Lintermans B, Van Craenenbroeck K. KLHL12 Promotes Non-Lysine Ubiquitination of the Dopamine Receptors D4.2 and D4.4, but Not of the ADHD-Associated D4.7 Variant. PLoS ONE. 2015;10:e0145654 pubmed publisher
|
| Jackson C, Best L, Lorenzo L, Casanova J, Wacker J, Bertz S, et al. A Multiplex Kindred with Hennekam Syndrome due to Homozygosity for a CCBE1 Mutation that does not Prevent Protein Expression. J Clin Immunol. 2016;36:19-27 pubmed publisher
|
| Ge C, Che L, Du C. The UBC Domain Is Required for BRUCE to Promote BRIT1/MCPH1 Function in DSB Signaling and Repair Post Formation of BRUCE-USP8-BRIT1 Complex. PLoS ONE. 2015;10:e0144957 pubmed publisher
|
| Thoms M, Ahmed Y, Maddi K, Hurt E, Sinning I. Concerted removal of the Erb1-Ytm1 complex in ribosome biogenesis relies on an elaborate interface. Nucleic Acids Res. 2016;44:926-39 pubmed publisher
|
| Adhikary S, Sanyal S, Basu M, Sengupta I, Sen S, Srivastava D, et al. Selective Recognition of H3.1K36 Dimethylation/H4K16 Acetylation Facilitates the Regulation of All-trans-retinoic Acid (ATRA)-responsive Genes by Putative Chromatin Reader ZMYND8. J Biol Chem. 2016;291:2664-81 pubmed publisher
|
| He L, Zhang Y, Ma G, Tan P, Li Z, Zang S, et al. Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation. elife. 2015;4: pubmed publisher
|
| Ando R, Shima H, Tamahara T, Sato Y, Watanabe Matsui M, Kato H, et al. The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization. J Biol Chem. 2016;291:1826-40 pubmed publisher
|
| Barrio Garcia C, Thoms M, Flemming D, Kater L, Berninghausen O, Baßler J, et al. Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling. Nat Struct Mol Biol. 2016;23:37-44 pubmed publisher
|
| Layer J, Alford C, McDonald W, Davé U. LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding. Mol Cell Biol. 2016;36:488-506 pubmed publisher
|
| Wan E, Abrams J, Weinberg R, Katchman A, Bayne J, Zakharov S, et al. Aberrant sodium influx causes cardiomyopathy and atrial fibrillation in mice. J Clin Invest. 2016;126:112-22 pubmed publisher
|
| Salinas E, Byrum S, Moreland L, Mackintosh S, Tackett A, Forrest J. Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. J Virol. 2016;90:1397-413 pubmed publisher
|
| Kaiserli E, Páldi K, O Donnell L, Batalov O, Pedmale U, Nusinow D, et al. Integration of Light and Photoperiodic Signaling in Transcriptional Nuclear Foci. Dev Cell. 2015;35:311-21 pubmed publisher
|
| Zhang L, Ward J, Cheng Z, Dernburg A. The auxin-inducible degradation (AID) system enables versatile conditional protein depletion in C. elegans. Development. 2015;142:4374-84 pubmed publisher
|
| Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, et al. IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nat Cell Biol. 2015;17:1546-55 pubmed publisher
|
| Prince T, Kijima T, Tatokoro M, Lee S, Tsutsumi S, Yim K, et al. Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants. PLoS ONE. 2015;10:e0141786 pubmed publisher
|
| Tavecchio M, Lisanti S, Bennett M, Languino L, Altieri D. Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism. Sci Rep. 2015;5:15981 pubmed publisher
|
| Zhang Q, Ma Y, Yang S, Xu B, Fei X. Small‑sized gold nanoparticles inhibit the proliferation and invasion of SW579 cells. Mol Med Rep. 2015;12:8313-9 pubmed publisher
|
| Du P, Yuan B, Cao J, Zhao J, Ding L, Chen L, et al. Methyltransferase-like 17 physically and functionally interacts with estrogen receptors. IUBMB Life. 2015;67:861-8 pubmed publisher
|
| Weis F, Giudice E, Churcher M, Jin L, Hilcenko C, Wong C, et al. Mechanism of eIF6 release from the nascent 60S ribosomal subunit. Nat Struct Mol Biol. 2015;22:914-9 pubmed publisher
|
| Tempera I, De Leo A, Kossenkov A, Cesaroni M, Song H, Dawany N, et al. Identification of MEF2B, EBF1, and IL6R as Direct Gene Targets of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Critical for EBV-Infected B-Lymphocyte Survival. J Virol. 2016;90:345-55 pubmed publisher
|
| van der Kant R, Jonker C, Wijdeven R, Bakker J, Janssen L, Klumperman J, et al. Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity. J Biol Chem. 2015;290:30280-90 pubmed publisher
|
| Jo A, Ham S, Lee G, Lee Y, Kim S, Lee Y, et al. Efficient Mitochondrial Genome Editing by CRISPR/Cas9. Biomed Res Int. 2015;2015:305716 pubmed publisher
|
| Zabrady K, Adamus M, Vondrova L, Liao C, Skoupilova H, Novakova M, et al. Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA. Nucleic Acids Res. 2016;44:1064-79 pubmed publisher
|
| Triboulet R, Pirouz M, Gregory R. A Single Let-7 MicroRNA Bypasses LIN28-Mediated Repression. Cell Rep. 2015;13:260-6 pubmed publisher
|
| Mohibi S, Srivastava S, Wang France J, Mirza S, Zhao X, Band H, et al. Alteration/Deficiency in Activation 3 (ADA3) Protein, a Cell Cycle Regulator, Associates with the Centromere through CENP-B and Regulates Chromosome Segregation. J Biol Chem. 2015;290:28299-310 pubmed publisher
|
| Trapani I, Toriello E, de Simone S, Colella P, Iodice C, Polishchuk E, et al. Improved dual AAV vectors with reduced expression of truncated proteins are safe and effective in the retina of a mouse model of Stargardt disease. Hum Mol Genet. 2015;24:6811-25 pubmed publisher
|
| Shen S, Guo M, Xiong Z, Yu Y, Zhao X, Zhang F, et al. AIF inhibits tumor metastasis by protecting PTEN from oxidation. EMBO Rep. 2015;16:1563-80 pubmed publisher
|
| Zhan Y, Kost Alimova M, Shi X, Leo E, Bardenhagen J, Shepard H, et al. Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery. Epigenetics Chromatin. 2015;8:37 pubmed publisher
|
| Ying T, Prabakaran P, Du L, Shi W, Feng Y, Wang Y, et al. Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody. Nat Commun. 2015;6:8223 pubmed publisher
|
| Chaumet A, Wright G, Seet S, Tham K, Gounko N, Bard F. Nuclear envelope-associated endosomes deliver surface proteins to the nucleus. Nat Commun. 2015;6:8218 pubmed publisher
|
| Otsuka K, Ito M, Ohkawara B, Masuda A, Kawakami Y, Sahashi K, et al. Collagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling. Sci Rep. 2015;5:13928 pubmed publisher
|
| Hsu T, Simon L, Neill N, Marcotte R, Sayad A, Bland C, et al. The spliceosome is a therapeutic vulnerability in MYC-driven cancer. Nature. 2015;525:384-8 pubmed publisher
|
| Maqbool A, Saitoh H, Franceschetti M, Stevenson C, Uemura A, Kanzaki H, et al. Structural basis of pathogen recognition by an integrated HMA domain in a plant NLR immune receptor. elife. 2015;4: pubmed publisher
|
| Wells M, Hicks S, Perera L, Blackshear P. Functional equivalence of an evolutionarily conserved RNA binding module. J Biol Chem. 2015;290:24413-23 pubmed publisher
|
| Simões Costa M, Stone M, Bronner M. Axud1 Integrates Wnt Signaling and Transcriptional Inputs to Drive Neural Crest Formation. Dev Cell. 2015;34:544-54 pubmed publisher
|
| Liao X, Zhang R, Lu Y, Prosdocimo D, Sangwung P, Zhang L, et al. Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis. J Clin Invest. 2015;125:3461-76 pubmed publisher
|
| Yang Z, Xian H, Hu J, Tian S, Qin Y, Wang R, et al. USP18 negatively regulates NF-κB signaling by targeting TAK1 and NEMO for deubiquitination through distinct mechanisms. Sci Rep. 2015;5:12738 pubmed publisher
|
| Vaughn L, Bragg D, Sharma N, Camargos S, Cardoso F, Patel R. Altered activation of protein kinase PKR and enhanced apoptosis in dystonia cells carrying a mutation in PKR activator protein PACT. J Biol Chem. 2015;290:22543-57 pubmed publisher
|
| Gaines W, Godin S, Kabbinavar F, Rao T, VanDemark A, Sung P, et al. Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52. Nat Commun. 2015;6:7834 pubmed publisher
|
| Nyegaard M, Rendtorff N, Nielsen M, Corydon T, Demontis D, Starnawska A, et al. A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment. PLoS Genet. 2015;11:e1005386 pubmed publisher
|
| Kortüm F, Harms F, Hennighausen N, Rosenberger G. αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor. PLoS ONE. 2015;10:e0132737 pubmed publisher
|
| Fiesel F, Ando M, Hudec R, Hill A, Castanedes Casey M, Caulfield T, et al. (Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation. EMBO Rep. 2015;16:1114-30 pubmed publisher
|
| Mukherjee S, Ura M, Hoey R, Kossiakoff A. A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction. J Mol Biol. 2015;427:2707-25 pubmed publisher
|
| Liu C, Lefebvre V. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis. Nucleic Acids Res. 2015;43:8183-203 pubmed publisher
|
| Munson M, Allen G, Toth R, Campbell D, Lucocq J, Ganley I. mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J. 2015;34:2272-90 pubmed publisher
|
| Gonzalez T, Liang Y, Nguyen B, Staskawicz B, Loqué D, Hammond M. Tight regulation of plant immune responses by combining promoter and suicide exon elements. Nucleic Acids Res. 2015;43:7152-61 pubmed publisher
|
| Hegde P, Dutta A, Sengupta S, Mitra J, Adhikari S, Tomkinson A, et al. The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD. J Biol Chem. 2015;290:20919-33 pubmed publisher
|
| Kazlauskaite A, MartÃnez Torres R, Wilkie S, Kumar A, Peltier J, González A, et al. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation. EMBO Rep. 2015;16:939-54 pubmed publisher
|
| Wilson J, Petrucelli A, Chen L, Koblansky A, Truax A, Oyama Y, et al. Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. Nat Med. 2015;21:906-13 pubmed publisher
|
| Witwicka H, Hwang S, Reyes Gutiérrez P, Jia H, Odgren P, Donahue L, et al. Studies of OC-STAMP in Osteoclast Fusion: A New Knockout Mouse Model, Rescue of Cell Fusion, and Transmembrane Topology. PLoS ONE. 2015;10:e0128275 pubmed publisher
|
| Monot M, Erny A, Gineys B, Desloire S, Dolmazon C, Aublin Gex A, et al. Early Steps of Jaagsiekte Sheep Retrovirus-Mediated Cell Transformation Involve the Interaction between Env and the RALBP1 Cellular Protein. J Virol. 2015;89:8462-73 pubmed publisher
|
| Pan H, Zhao X, Zhang X, Abouelsoud M, Sun J, April C, et al. Translational Initiation at a Non-AUG Start Codon for Human and Mouse Negative Elongation Factor-B. PLoS ONE. 2015;10:e0127422 pubmed publisher
|
| Deng G, Nagai Y, Xiao Y, Li Z, Dai S, Ohtani T, et al. Pim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal Phosphorylation. J Biol Chem. 2015;290:20211-20 pubmed publisher
|
| Letourneau A, Cobellis G, Fort A, Santoni F, Garieri M, Falconnet E, et al. HSA21 Single-Minded 2 (Sim2) Binding Sites Co-Localize with Super-Enhancers and Pioneer Transcription Factors in Pluripotent Mouse ES Cells. PLoS ONE. 2015;10:e0126475 pubmed publisher
|
| He R, Peng J, Yuan P, Xu F, Wei W. Divergent roles of BECN1 in LC3 lipidation and autophagosomal function. Autophagy. 2015;11:740-7 pubmed publisher
|
| Rojas Fernandez A, Herhaus L, MacArtney T, Lachaud C, Hay R, Sapkota G. Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9. Sci Rep. 2015;5:9811 pubmed publisher
|
| Chen G, Gorelik L, Simon K, Pavlenco A, Cheung A, Brickelmaier M, et al. Synthetic antibodies and peptides recognizing progressive multifocal leukoencephalopathy-specific point mutations in polyomavirus JC capsid viral protein 1. MAbs. 2015;7:681-92 pubmed publisher
|
| Panigrahi S, Hopkins K, Lieberman H. Regulation of NEIL1 protein abundance by RAD9 is important for efficient base excision repair. Nucleic Acids Res. 2015;43:4531-46 pubmed publisher
|
| Herhaus L, Pérez Oliva A, Cozza G, Gourlay R, Weidlich S, Campbell D, et al. Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization. Sci Signal. 2015;8:ra35 pubmed publisher
|
| Serth K, Schuster Gossler K, Kremmer E, Hansen B, Marohn Köhn B, Gossler A. O-fucosylation of DLL3 is required for its function during somitogenesis. PLoS ONE. 2015;10:e0123776 pubmed publisher
|
| Li D, Xu T, Cao Y, Wang H, Li L, Chen S, et al. A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis. Proc Natl Acad Sci U S A. 2015;112:5017-22 pubmed publisher
|
| Chakraborty A, Diefenbacher M, Mylona A, Kassel O, Behrens A. The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling. Nat Commun. 2015;6:6782 pubmed publisher
|
| Clavel M, Pélissier T, Descombin J, Jean V, Picart C, Charbonel C, et al. Parallel action of AtDRB2 and RdDM in the control of transposable element expression. BMC Plant Biol. 2015;15:70 pubmed publisher
|
| Gustin J, Bai Y, Moses A, Douglas J. Ebola Virus Glycoprotein Promotes Enhanced Viral Egress by Preventing Ebola VP40 From Associating With the Host Restriction Factor BST2/Tetherin. J Infect Dis. 2015;212 Suppl 2:S181-90 pubmed publisher
|
| Grossmann A, Benlasfer N, Birth P, Hegele A, Wachsmuth F, Apelt L, et al. Phospho-tyrosine dependent protein-protein interaction network. Mol Syst Biol. 2015;11:794 pubmed publisher
|
| Dong T, Li C, Wang X, Dian L, Zhang X, Li L, et al. Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. Nat Commun. 2015;6:6522 pubmed publisher
|
| Lu W, Fang L, Ouyang B, Zhang X, Zhan S, Feng X, et al. Actl6a protects embryonic stem cells from differentiating into primitive endoderm. Stem Cells. 2015;33:1782-93 pubmed publisher
|
| Zheng Y, Adams T, Zhi H, Yu M, Wen R, Newman P, et al. Restoration of responsiveness of phospholipase Cγ2-deficient platelets by enforced expression of phospholipase Cγ1. PLoS ONE. 2015;10:e0119739 pubmed publisher
|
| Hsiau T, Sukovich D, Elms P, Prince R, Strittmatter T, Stritmatter T, et al. A method for multiplex gene synthesis employing error correction based on expression. PLoS ONE. 2015;10:e0119927 pubmed publisher
|
| Kato K, Bhattaram P, Penzo Méndez A, Gadi A, Lefebvre V. SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling. J Bone Miner Res. 2015;30:1560-71 pubmed publisher
|
| Mo J, Meng Z, Kim Y, Park H, Hansen C, Kim S, et al. Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Nat Cell Biol. 2015;17:500-10 pubmed publisher
|
| Saucet S, Ma Y, Sarris P, Furzer O, Sohn K, Jones J. Two linked pairs of Arabidopsis TNL resistance genes independently confer recognition of bacterial effector AvrRps4. Nat Commun. 2015;6:6338 pubmed publisher
|
| Hwang B, Phan F, McCool K, Choi E, You J, Johnson A, et al. Quantification of cellular NEMO content and its impact on NF-κB activation by genotoxic stress. PLoS ONE. 2015;10:e0116374 pubmed publisher
|
| Siatecka M, Soni S, Planutis A, Bieker J. Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3). J Biol Chem. 2015;290:9929-40 pubmed publisher
|
| Boëda B, Etienne Manneville S. Spectrin binding motifs regulate Scribble cortical dynamics and polarity function. elife. 2015;4: pubmed publisher
|
| Kärblane K, Gerassimenko J, Nigul L, Piirsoo A, Smialowska A, Vinkel K, et al. ABCE1 is a highly conserved RNA silencing suppressor. PLoS ONE. 2015;10:e0116702 pubmed publisher
|
| Harms M, Lim H, Ho Y, Shapira S, Ishibashi J, Rajakumari S, et al. PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program. Genes Dev. 2015;29:298-307 pubmed publisher
|
| Li D, Dong Q, Tao Q, Gu J, Cui Y, Jiang X, et al. c-Abl regulates proteasome abundance by controlling the ubiquitin-proteasomal degradation of PSMA7 subunit. Cell Rep. 2015;10:484-96 pubmed publisher
|
| Ahmad F, Shen W, Vandeput F, Szabo Fresnais N, Krall J, Degerman E, et al. Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2. J Biol Chem. 2015;290:6763-76 pubmed publisher
|
| Zhong X, Hale C, Nguyen M, Ausin I, Groth M, Hetzel J, et al. Domains rearranged methyltransferase3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis. Proc Natl Acad Sci U S A. 2015;112:911-6 pubmed publisher
|
| Yuan P, Zhang H, Cai C, Zhu S, Zhou Y, Yang X, et al. Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B. Cell Res. 2015;25:157-68 pubmed publisher
|
| Chiarella E, Carrà G, Scicchitano S, Codispoti B, Mega T, Lupia M, et al. UMG Lenti: novel lentiviral vectors for efficient transgene- and reporter gene expression in human early hematopoietic progenitors. PLoS ONE. 2014;9:e114795 pubmed publisher
|
| Beveridge R, Staples C, Patil A, Myers K, Maslen S, Skehel J, et al. The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling. Cell Cycle. 2014;13:3450-9 pubmed publisher
|
| Puzzi L, Marchetti L, Peverali F, Biamonti G, Giacca M. DNA-protein interaction dynamics at the Lamin B2 replication origin. Cell Cycle. 2015;14:64-73 pubmed publisher
|
| Groth M, Stroud H, Feng S, Greenberg M, Vashisht A, Wohlschlegel J, et al. SNF2 chromatin remodeler-family proteins FRG1 and -2 are required for RNA-directed DNA methylation. Proc Natl Acad Sci U S A. 2014;111:17666-71 pubmed publisher
|
| Lam S, Martell J, Kamer K, Deerinck T, Ellisman M, Mootha V, et al. Directed evolution of APEX2 for electron microscopy and proximity labeling. Nat Methods. 2015;12:51-4 pubmed publisher
|
| Caulfield T, Fiesel F, Moussaud Lamodière E, Dourado D, Flores S, Springer W. Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin. PLoS Comput Biol. 2014;10:e1003935 pubmed publisher
|
| Sagnier S, Daussy C, Borel S, Robert Hebmann V, Faure M, Blanchet F, et al. Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes. J Virol. 2015;89:615-25 pubmed publisher
|
| Zheng Q, Ahlawat S, Schaefer A, Mahoney T, Koushika S, Nonet M. The vesicle protein SAM-4 regulates the processivity of synaptic vesicle transport. PLoS Genet. 2014;10:e1004644 pubmed publisher
|
| Wang X, Li Y, Liu S, Yu X, Li L, Shi C, et al. Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense. Proc Natl Acad Sci U S A. 2014;111:15438-43 pubmed publisher
|
| Kitaura Y, Hojo H, Komiyama Y, Takato T, Chung U, Ohba S. Gli1 haploinsufficiency leads to decreased bone mass with an uncoupling of bone metabolism in adult mice. PLoS ONE. 2014;9:e109597 pubmed publisher
|
| Gegg M, Böttcher A, Burtscher I, Hasenoeder S, Van Campenhout C, Aichler M, et al. Flattop regulates basal body docking and positioning in mono- and multiciliated cells. elife. 2014;3: pubmed publisher
|
| Hahn F, Setz C, Friedrich M, Rauch P, Solbak S, Frøystein N, et al. Mutation of the highly conserved Ser-40 of the HIV-1 p6 gag protein to Phe causes the formation of a hydrophobic patch, enhances membrane association, and polyubiquitination of Gag. Viruses. 2014;6:3738-65 pubmed publisher
|
| Kuzina E, Kudriaeva A, Smirnov I, Dubina M, Gabibov A, Belogurov A. Glatiramer acetate and nanny proteins restrict access of the multiple sclerosis autoantigen myelin basic protein to the 26S proteasome. Biomed Res Int. 2014;2014:926394 pubmed publisher
|
| Schmidt J, Dalby A, Cech T. Identification of human TERT elements necessary for telomerase recruitment to telomeres. elife. 2014;3: pubmed publisher
|
| Chmielecki J, Hutchinson K, Frampton G, Chalmers Z, Johnson A, Shi C, et al. Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes. Cancer Discov. 2014;4:1398-405 pubmed publisher
|
| Streeter J, Schickling B, Jiang S, Stanic B, Thiel W, Gakhar L, et al. Phosphorylation of Nox1 regulates association with NoxA1 activation domain. Circ Res. 2014;115:911-8 pubmed publisher
|
| Giuntoli B, Lee S, Licausi F, Kosmacz M, Oosumi T, van Dongen J, et al. A trihelix DNA binding protein counterbalances hypoxia-responsive transcriptional activation in Arabidopsis. PLoS Biol. 2014;12:e1001950 pubmed publisher
|
| Thornton J, Du P, Jing L, Sjekloća L, Lin S, Grossi E, et al. Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Nucleic Acids Res. 2014;42:11777-91 pubmed publisher
|
| Chan Y, West S. Spatial control of the GEN1 Holliday junction resolvase ensures genome stability. Nat Commun. 2014;5:4844 pubmed publisher
|
| Baschieri F, Confalonieri S, Bertalot G, Di Fiore P, Dietmaier W, Leist M, et al. Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis. Nat Commun. 2014;5:4839 pubmed publisher
|
| Swygert S, Manning B, Senapati S, Kaur P, Lindsay S, Demeler B, et al. Solution-state conformation and stoichiometry of yeast Sir3 heterochromatin fibres. Nat Commun. 2014;5:4751 pubmed publisher
|
| Kumar D, Lassar A. Fibroblast growth factor maintains chondrogenic potential of limb bud mesenchymal cells by modulating DNMT3A recruitment. Cell Rep. 2014;8:1419-31 pubmed publisher
|
| Horikawa I, Fujita K, Jenkins L, Hiyoshi Y, Mondal A, Vojtesek B, et al. Autophagic degradation of the inhibitory p53 isoform ?133p53? as a regulatory mechanism for p53-mediated senescence. Nat Commun. 2014;5:4706 pubmed publisher
|
| Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher
|
| Tsai Y, Lai C, Lai C, Chang K, Wu K, Tseng S, et al. The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth. Oncotarget. 2014;5:6425-36 pubmed
|
| Christian F, Krause E, Houslay M, Baillie G. PKA phosphorylation of p62/SQSTM1 regulates PB1 domain interaction partner binding. Biochim Biophys Acta. 2014;1843:2765-74 pubmed publisher
|
| Lee I, Leung T, Tan I. Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics. J Biol Chem. 2014;289:26989-7003 pubmed publisher
|
| Goolam M, Ward J, Avlani V, Leach K, Christopoulos A, Conigrave A. Roles of intraloops-2 and -3 and the proximal C-terminus in signalling pathway selection from the human calcium-sensing receptor. FEBS Lett. 2014;588:3340-6 pubmed publisher
|
| Amelio A, Fallahi M, Schaub F, Zhang M, Lawani M, Alperstein A, et al. CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement. Proc Natl Acad Sci U S A. 2014;111:E3260-8 pubmed publisher
|
| Hanssum A, Zhong Z, Rousseau A, Krzyzosiak A, Sigurdardottir A, Bertolotti A. An inducible chaperone adapts proteasome assembly to stress. Mol Cell. 2014;55:566-77 pubmed publisher
|
| Yuan B, Cheng L, Chiang H, Xu X, Han Y, Su H, et al. A phosphotyrosine switch determines the antitumor activity of ER?. J Clin Invest. 2014;124:3378-90 pubmed publisher
|
| Ryu H, Cho H, Bae W, Hwang I. Control of early seedling development by BES1/TPL/HDA19-mediated epigenetic regulation of ABI3. Nat Commun. 2014;5:4138 pubmed publisher
|
| Fiesel F, Moussaud Lamodière E, Ando M, Springer W. A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci. 2014;127:3488-504 pubmed publisher
|
| Baron Y, Pedrioli P, Tyagi K, Johnson C, Wood N, Fountaine D, et al. VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase. BMC Biol. 2014;12:39 pubmed publisher
|
| Lee Y, Dominy J, Choi Y, Jurczak M, Tolliday N, Camporez J, et al. Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression. Nature. 2014;510:547-51 pubmed publisher
|
| Lehmann M, Pahlmann M, Jérôme H, Busch C, Lelke M, Gunther S. Role of the C terminus of Lassa virus L protein in viral mRNA synthesis. J Virol. 2014;88:8713-7 pubmed publisher
|
| Prabhu Y, Blanco E, Liu M, Peinado J, Wheeler M, Gekakis N, et al. Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function. Endocrinology. 2014;155:2391-401 pubmed publisher
|
| Wicht O, Li W, Willems L, Meuleman T, Wubbolts R, van Kuppeveld F, et al. Proteolytic activation of the porcine epidemic diarrhea coronavirus spike fusion protein by trypsin in cell culture. J Virol. 2014;88:7952-61 pubmed publisher
|
| Liu J, MCCLELAND M, Stawiski E, Gnad F, Mayba O, Haverty P, et al. Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer. Nat Commun. 2014;5:3830 pubmed publisher
|
| Moissiard G, Bischof S, Husmann D, Pastor W, Hale C, Yen L, et al. Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers. Proc Natl Acad Sci U S A. 2014;111:7474-9 pubmed publisher
|
| Kinsey C, Balakrishnan V, O Dell M, Huang J, Newman L, Whitney Miller C, et al. Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression. Cell Rep. 2014;7:1143-55 pubmed publisher
|
| Nu ez J, Kranzusch P, Noeske J, Wright A, Davies C, Doudna J. Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity. Nat Struct Mol Biol. 2014;21:528-34 pubmed publisher
|
| Rossi M, Rotblat B, Ansell K, Amelio I, Caraglia M, Misso G, et al. High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy. Cell Death Dis. 2014;5:e1203 pubmed publisher
|
| Banerjee S, Zagórska A, Deak M, Campbell D, Prescott A, Alessi D. Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase. Biochem J. 2014;461:233-45 pubmed publisher
|
| Lee C, Freinkman E, Sabatini D, Ploegh H. The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D. J Biol Chem. 2014;289:17124-31 pubmed publisher
|
| Attanasio C, Nord A, Zhu Y, Blow M, Biddie S, Mendenhall E, et al. Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis. Genome Res. 2014;24:920-9 pubmed publisher
|
| Giudice J, Xia Z, Wang E, Scavuzzo M, Ward A, Kalsotra A, et al. Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development. Nat Commun. 2014;5:3603 pubmed publisher
|
| O Neill D, Williamson S, Alkharaif D, Monteiro I, Goudreault M, Gaughan L, et al. SETD6 controls the expression of estrogen-responsive genes and proliferation of breast carcinoma cells. Epigenetics. 2014;9:942-50 pubmed publisher
|
| Egan E, Braun C, Gygi S, Moazed D. Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex. RNA. 2014;20:867-81 pubmed publisher
|
| Schaller T, Pollpeter D, Apolonia L, Goujon C, Malim M. Nuclear import of SAMHD1 is mediated by a classical karyopherin ?/?1 dependent pathway and confers sensitivity to VpxMAC induced ubiquitination and proteasomal degradation. Retrovirology. 2014;11:29 pubmed publisher
|
| Taylor K, Mackay A, Truffaux N, Butterfield Y, Morozova O, Philippe C, et al. Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma. Nat Genet. 2014;46:457-461 pubmed publisher
|
| Wang J, Kang R, Huang H, Xi X, Wang B, Wang J, et al. Hepatitis C virus core protein activates autophagy through EIF2AK3 and ATF6 UPR pathway-mediated MAP1LC3B and ATG12 expression. Autophagy. 2014;10:766-84 pubmed publisher
|
| Majkut J, Sgobba M, Holohan C, Crawford N, Logan A, Kerr E, et al. Differential affinity of FLIP and procaspase 8 for FADD's DED binding surfaces regulates DISC assembly. Nat Commun. 2014;5:3350 pubmed publisher
|
| Yang W, Cooke M, Duckett C, Yang X, Dorsey J. Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells. Cell Cycle. 2014;13:992-1005 pubmed publisher
|
| Pogenberg V, Consani Textor L, Vanhille L, Holton S, Sieweke M, Wilmanns M. Design of a bZip transcription factor with homo/heterodimer-induced DNA-binding preference. Structure. 2014;22:466-77 pubmed publisher
|
| Klein C, Wu Y, Vogel P, Goebel H, Bonnemann C, Zukosky K, et al. Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons. Neurology. 2014;82:873-8 pubmed publisher
|
| McKay D, Xi L, Barthel K, Cech T. Structure and function of steroid receptor RNA activator protein, the proposed partner of SRA noncoding RNA. J Mol Biol. 2014;426:1766-1785 pubmed publisher
|
| Portnoff A, Stephens E, Varner J, DeLisa M. Ubiquibodies, synthetic E3 ubiquitin ligases endowed with unnatural substrate specificity for targeted protein silencing. J Biol Chem. 2014;289:7844-55 pubmed publisher
|
| Waterfield M, Khan I, Cortez J, Fan U, Metzger T, Greer A, et al. The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance. Nat Immunol. 2014;15:258-65 pubmed publisher
|
| Gilson T, Cheng C, Hur W, Blanchette P, Branton P. Analysis of the Cullin binding sites of the E4orf6 proteins of human adenovirus E3 ubiquitin ligases. J Virol. 2014;88:3885-97 pubmed publisher
|
| Radhakrishnan S, den Besten W, Deshaies R. p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition. elife. 2014;3:e01856 pubmed publisher
|
| Nagy H, Paar M, Heier C, Moustafa T, Hofer P, Haemmerle G, et al. Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A. Biochim Biophys Acta. 2014;1841:588-94 pubmed publisher
|
| Abe M, Naqvi A, Hendriks G, Feltzin V, Zhu Y, Grigoriev A, et al. Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila. Genes Dev. 2014;28:44-57 pubmed publisher
|
| Pepe A, West S. Substrate specificity of the MUS81-EME2 structure selective endonuclease. Nucleic Acids Res. 2014;42:3833-45 pubmed publisher
|
| Cui J, Song Y, Li Y, Zhu Q, Tan P, Qin Y, et al. USP3 inhibits type I interferon signaling by deubiquitinating RIG-I-like receptors. Cell Res. 2014;24:400-16 pubmed publisher
|
| Andresen C, Smedegaard S, Sylvestersen K, Svensson C, Iglesias Gato D, Cazzamali G, et al. Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase. J Biol Chem. 2014;289:2043-54 pubmed publisher
|
| Mueller J, McGeough M, Pena C, Sivagnanam M. Functional consequences of EpCam mutation in mice and men. Am J Physiol Gastrointest Liver Physiol. 2014;306:G278-88 pubmed publisher
|
| Katayama K, Yamaguchi M, Noguchi K, Sugimoto Y. Protein phosphatase complex PP5/PPP2R3C dephosphorylates P-glycoprotein/ABCB1 and down-regulates the expression and function. Cancer Lett. 2014;345:124-31 pubmed publisher
|
| Tsioras K, Papastefanaki F, Politis P, Matsas R, Gaitanou M. Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells. PLoS ONE. 2013;8:e82172 pubmed publisher
|
| Kitayama Y, Nishiwaki Ohkawa T, Sugisawa Y, Kondo T. KaiC intersubunit communication facilitates robustness of circadian rhythms in cyanobacteria. Nat Commun. 2013;4:2897 pubmed publisher
|
| Araki K, Kawauchi K, Hirata H, Yamamoto M, Taya Y. Cytoplasmic translocation of the retinoblastoma protein disrupts sarcomeric organization. elife. 2013;2:e01228 pubmed publisher
|
| Trapani I, Colella P, Sommella A, Iodice C, Cesi G, de Simone S, et al. Effective delivery of large genes to the retina by dual AAV vectors. EMBO Mol Med. 2014;6:194-211 pubmed publisher
|
| Shi C, Schisler J, Rubel C, Tan S, Song B, McDonough H, et al. Ataxia and hypogonadism caused by the loss of ubiquitin ligase activity of the U box protein CHIP. Hum Mol Genet. 2014;23:1013-24 pubmed publisher
|
| Nakashima M, Nandakumar J, Sullivan K, Espinosa J, Cech T. Inhibition of telomerase recruitment and cancer cell death. J Biol Chem. 2013;288:33171-80 pubmed publisher
|
| Reichert S, Randall R, Hill C. A BMP regulatory network controls ectodermal cell fate decisions at the neural plate border. Development. 2013;140:4435-44 pubmed publisher
|
| Mural R, Liu Y, Rosebrock T, Brady J, Hamera S, Connor R, et al. The tomato Fni3 lysine-63-specific ubiquitin-conjugating enzyme and suv ubiquitin E2 variant positively regulate plant immunity. Plant Cell. 2013;25:3615-31 pubmed publisher
|
| Herhaus L, Al Salihi M, MacArtney T, Weidlich S, Sapkota G. OTUB1 enhances TGF? signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3. Nat Commun. 2013;4:2519 pubmed publisher
|
| Gong C, Tang Y, Maquat L. mRNA-mRNA duplexes that autoelicit Staufen1-mediated mRNA decay. Nat Struct Mol Biol. 2013;20:1214-20 pubmed publisher
|
| Martinez N, Chang H, Borrajo J, Gregory R. The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly. RNA. 2013;19:1583-93 pubmed publisher
|
| Sankar S, Tanner J, Bell R, Chaturvedi A, Randall R, Beckerle M, et al. A novel role for keratin 17 in coordinating oncogenic transformation and cellular adhesion in Ewing sarcoma. Mol Cell Biol. 2013;33:4448-60 pubmed publisher
|
| Hashimoto M, Suizu F, Tokuyama W, Noguchi H, Hirata N, Matsuda Lennikov M, et al. Protooncogene TCL1b functions as an Akt kinase co-activator that exhibits oncogenic potency in vivo. Oncogenesis. 2013;2:e70 pubmed publisher
|
| Demir K, Kirsch N, Beretta C, Erdmann G, Ingelfinger D, Moro E, et al. RAB8B is required for activity and caveolar endocytosis of LRP6. Cell Rep. 2013;4:1224-34 pubmed publisher
|
| Gu X, Wang Y, He Y. Photoperiodic regulation of flowering time through periodic histone deacetylation of the florigen gene FT. PLoS Biol. 2013;11:e1001649 pubmed publisher
|
| Bharucha N, Liu Y, Papanikou E, McMahon C, Esaki M, Jeffrey P, et al. Sec16 influences transitional ER sites by regulating rather than organizing COPII. Mol Biol Cell. 2013;24:3406-19 pubmed publisher
|
| Lu Y, Zhang L, Liao X, Sangwung P, Prosdocimo D, Zhou G, et al. Kruppel-like factor 15 is critical for vascular inflammation. J Clin Invest. 2013;123:4232-41 pubmed publisher
|
| Orebaugh C, Fye J, Harvey S, Hollis T, Wilkinson J, Perrino F. The TREX1 C-terminal region controls cellular localization through ubiquitination. J Biol Chem. 2013;288:28881-92 pubmed publisher
|
| Lee Y, Karuppagounder S, Shin J, Lee Y, Ko H, Swing D, et al. Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss. Nat Neurosci. 2013;16:1392-400 pubmed publisher
|
| Hayes H, Moss L, Schisler J, Haldeman J, Zhang Z, Rosenberg P, et al. Pdx-1 activates islet ?- and ?-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2. Mol Cell Biol. 2013;33:4017-29 pubmed publisher
|
| Kreßner C, Nollau P, Grosse R, Brandt D. Functional interaction of SCAI with the SWI/SNF complex for transcription and tumor cell invasion. PLoS ONE. 2013;8:e69947 pubmed publisher
|
| Xiang Z, Ren H, Hu Y, Coin I, Wei J, Cang H, et al. Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity. Nat Methods. 2013;10:885-8 pubmed publisher
|
| Zaug A, Crary S, Jesse Fioravanti M, Campbell K, Cech T. Many disease-associated variants of hTERT retain high telomerase enzymatic activity. Nucleic Acids Res. 2013;41:8969-78 pubmed publisher
|
| Telkoparan P, Erkek S, Yaman E, Alotaibi H, Bayık D, Tazebay U. Coiled-coil domain containing protein 124 is a novel centrosome and midbody protein that interacts with the Ras-guanine nucleotide exchange factor 1B and is involved in cytokinesis. PLoS ONE. 2013;8:e69289 pubmed publisher
|
| Han X, Liu D, Zhang Y, Li Y, Lu W, Chen J, et al. Akt regulates TPP1 homodimerization and telomere protection. Aging Cell. 2013;12:1091-9 pubmed publisher
|
| Liu H, Jiang Y, Jin X, Zhu L, Shen X, Zhang Q, et al. CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity. Reprod Biol Endocrinol. 2013;11:64 pubmed publisher
|
| Yin Q, Sester D, Tian Y, Hsiao Y, Lu A, Cridland J, et al. Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation. Cell Rep. 2013;4:327-39 pubmed publisher
|
| Derkacheva M, Steinbach Y, Wildhaber T, Mozgová I, Mahrez W, Nanni P, et al. Arabidopsis MSI1 connects LHP1 to PRC2 complexes. EMBO J. 2013;32:2073-85 pubmed publisher
|
| Gu X, Le C, Wang Y, Li Z, Jiang D, Wang Y, et al. Arabidopsis FLC clade members form flowering-repressor complexes coordinating responses to endogenous and environmental cues. Nat Commun. 2013;4:1947 pubmed publisher
|
| Uehata T, Iwasaki H, Vandenbon A, Matsushita K, Hernandez Cuellar E, Kuniyoshi K, et al. Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation. Cell. 2013;153:1036-49 pubmed publisher
|
| Pavlova N, Pallasch C, Elia A, Braun C, Westbrook T, Hemann M, et al. A role for PVRL4-driven cell-cell interactions in tumorigenesis. elife. 2013;2:e00358 pubmed publisher
|
| Taylor B, Nik Zainal S, Wu Y, Stebbings L, Raine K, Campbell P, et al. DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis. elife. 2013;2:e00534 pubmed publisher
|
| Vogt D, Camus G, Herker E, Webster B, Tsou C, Greene W, et al. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. PLoS Pathog. 2013;9:e1003302 pubmed publisher
|
| Maruyama A, Mimura J, Harada N, Itoh K. Nrf2 activation is associated with Z-DNA formation in the human HO-1 promoter. Nucleic Acids Res. 2013;41:5223-34 pubmed publisher
|
| Wiles E, Lui Sargent B, Bell R, Lessnick S. BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma. PLoS ONE. 2013;8:e59369 pubmed publisher
|
| Uekita T, Fujii S, Miyazawa Y, Hashiguchi A, Abe H, Sakamoto M, et al. Suppression of autophagy by CUB domain-containing protein 1 signaling is essential for anchorage-independent survival of lung cancer cells. Cancer Sci. 2013;104:865-70 pubmed publisher
|
| Martinez N, Gregory R. Argonaute2 expression is post-transcriptionally coupled to microRNA abundance. RNA. 2013;19:605-12 pubmed publisher
|
| Marino D, Froidure S, Canonne J, Ben Khaled S, Khafif M, Pouzet C, et al. Arabidopsis ubiquitin ligase MIEL1 mediates degradation of the transcription factor MYB30 weakening plant defence. Nat Commun. 2013;4:1476 pubmed publisher
|
| Davies O, Lin C, Radzisheuskaya A, Zhou X, Taube J, Blin G, et al. Tcf15 primes pluripotent cells for differentiation. Cell Rep. 2013;3:472-84 pubmed publisher
|
| Koreishi M, Yu S, Oda M, Honjo Y, Satoh A. CK2 phosphorylates Sec31 and regulates ER-To-Golgi trafficking. PLoS ONE. 2013;8:e54382 pubmed publisher
|
| Malvezzi F, Litos G, Schleiffer A, Heuck A, Mechtler K, Clausen T, et al. A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors. EMBO J. 2013;32:409-23 pubmed publisher
|
| Hota S, Bhardwaj S, Deindl S, Lin Y, Zhuang X, Bartholomew B. Nucleosome mobilization by ISW2 requires the concerted action of the ATPase and SLIDE domains. Nat Struct Mol Biol. 2013;20:222-9 pubmed publisher
|
| Taşdelen I, Van Beekum O, Gorbenko O, Fleskens V, van den Broek N, Koppen A, et al. The serine/threonine phosphatase PPM1B (PP2C?) selectively modulates PPAR? activity. Biochem J. 2013;451:45-53 pubmed publisher
|
| Vervoort S, Lourenço A, van Boxtel R, Coffer P. SOX4 mediates TGF-?-induced expression of mesenchymal markers during mammary cell epithelial to mesenchymal transition. PLoS ONE. 2013;8:e53238 pubmed publisher
|
| Leach M, Budge S, Walker L, Munro C, Cowen L, Brown A. Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast. PLoS Pathog. 2012;8:e1003069 pubmed publisher
|
| Jalah R, Rosati M, Ganneru B, Pilkington G, Valentin A, Kulkarni V, et al. The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production. J Biol Chem. 2013;288:6763-76 pubmed publisher
|
| Han J, Hubbard B, Lee J, Montagna C, Lee H, Sinclair D, et al. Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene. Cell Cycle. 2013;12:263-70 pubmed publisher
|
| Polyakova O, Borman S, Grimley R, Vamathevan J, Hayes B, Solari R. Identification of novel interacting partners of Sirtuin6. PLoS ONE. 2012;7:e51555 pubmed publisher
|
| Ikui A, Rossio V, Schroeder L, Yoshida S. A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication. PLoS Genet. 2012;8:e1003099 pubmed publisher
|
| Graham C, Matta H, Yang Y, Yi H, Suo Y, Tolani B, et al. Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor-induced growth arrest and apoptosis through NF-?B activation. J Virol. 2013;87:2242-52 pubmed publisher
|
| New L, Keyvani Chahi A, Jones N. Direct regulation of nephrin tyrosine phosphorylation by Nck adaptor proteins. J Biol Chem. 2013;288:1500-10 pubmed publisher
|
| Luo D, Bernard D, Balk J, Hai H, Cui X. The DUF59 family gene AE7 acts in the cytosolic iron-sulfur cluster assembly pathway to maintain nuclear genome integrity in Arabidopsis. Plant Cell. 2012;24:4135-48 pubmed publisher
|
| Nandakumar J, Bell C, Weidenfeld I, Zaug A, Leinwand L, Cech T. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature. 2012;492:285-9 pubmed publisher
|
| Chin B, Ryan O, Lewitter F, Boone C, Fink G. Genetic variation in Saccharomyces cerevisiae: circuit diversification in a signal transduction network. Genetics. 2012;192:1523-32 pubmed publisher
|
| Wildenhain S, Ingenhag D, Ruckert C, Degistirici O, Dugas M, Meisel R, et al. Homeobox protein HB9 binds to the prostaglandin E receptor 2 promoter and inhibits intracellular cAMP mobilization in leukemic cells. J Biol Chem. 2012;287:40703-12 pubmed publisher
|
| Ren Y, Chaerkady R, Hu S, Wan J, Qian J, Zhu H, et al. Unbiased discovery of interactions at a control locus driving expression of the cancer-specific therapeutic and diagnostic target, mesothelin. J Proteome Res. 2012;11:5301-10 pubmed publisher
|
| Ju Y, Mizutani T, Imamichi Y, Yazawa T, Matsumura T, Kawabe S, et al. Nuclear receptor 5A (NR5A) family regulates 5-aminolevulinic acid synthase 1 (ALAS1) gene expression in steroidogenic cells. Endocrinology. 2012;153:5522-34 pubmed publisher
|
| Du J, Zhong X, Bernatavichute Y, Stroud H, Feng S, Caro E, et al. Dual binding of chromomethylase domains to H3K9me2-containing nucleosomes directs DNA methylation in plants. Cell. 2012;151:167-80 pubmed publisher
|
| Juhasz S, Balogh D, Hajdu I, Burkovics P, Villamil M, Zhuang Z, et al. Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance. Nucleic Acids Res. 2012;40:10795-808 pubmed publisher
|
| Silveira Neto A, Leal L, Emerman A, Henderson K, Piskounova E, Henderson B, et al. Absence of functional LIN28B mutations in a large cohort of patients with idiopathic central precocious puberty. Horm Res Paediatr. 2012;78:144-50 pubmed publisher
|
| Tripurani S, Cook R, Eldin K, Pangas S. BMP-specific SMADs function as novel repressors of PDGFA and modulate its expression in ovarian granulosa cells and tumors. Oncogene. 2013;32:3877-85 pubmed publisher
|
| Frietze S, Wang R, Yao L, Tak Y, Ye Z, Gaddis M, et al. Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3. Genome Biol. 2012;13:R52 pubmed publisher
|
| Gannon A, Frizzell A, Healy E, Lahue R. MutS? and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells. Nucleic Acids Res. 2012;40:10324-33 pubmed publisher
|
| Chamberlain C, Ranum L. Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise. Hum Mol Genet. 2012;21:4645-54 pubmed publisher
|
| Gálvez Santisteban M, Rodriguez Fraticelli A, Bryant D, Vergarajauregui S, Yasuda T, Bañón Rodríguez I, et al. Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells. Nat Cell Biol. 2012;14:838-49 pubmed publisher
|
| Kipnis Y, Baker D. Comparison of designed and randomly generated catalysts for simple chemical reactions. Protein Sci. 2012;21:1388-95 pubmed publisher
|
| Grimley R, Polyakova O, Vamathevan J, McKenary J, Hayes B, Patel C, et al. Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NF?B responses. PLoS ONE. 2012;7:e39847 pubmed publisher
|
| Liu Y, Peng L, Seto E, Huang S, Qiu Y. Modulation of histone deacetylase 6 (HDAC6) nuclear import and tubulin deacetylase activity through acetylation. J Biol Chem. 2012;287:29168-74 pubmed publisher
|
| Al Salihi M, Herhaus L, MacArtney T, Sapkota G. USP11 augments TGFβ signalling by deubiquitylating ALK5. Open Biol. 2012;2:120063 pubmed publisher
|
| Weston R, Peeters H, Ahel D. ZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress response. Genes Dev. 2012;26:1558-72 pubmed publisher
|
| Chang H, Martinez N, Thornton J, Hagan J, Nguyen K, Gregory R. Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation. Nat Commun. 2012;3:923 pubmed publisher
|
| Ishida M, Shimojo H, Hayashi A, Kawaguchi R, Ohtani Y, Uegaki K, et al. Intrinsic nucleic acid-binding activity of Chp1 chromodomain is required for heterochromatic gene silencing. Mol Cell. 2012;47:228-41 pubmed publisher
|
| Schmidt P, Sparrow L, Attwood R, Xiao X, Adams T, McKimm Breschkin J. Taking down the FLAG! How insect cell expression challenges an established tag-system. PLoS ONE. 2012;7:e37779 pubmed publisher
|
| Li G, Zhang J, Li J, Yang Z, Huang H, Xu L. Imitation Switch chromatin remodeling factors and their interacting RINGLET proteins act together in controlling the plant vegetative phase in Arabidopsis. Plant J. 2012;72:261-70 pubmed publisher
|
| Ausin I, Greenberg M, Simanshu D, Hale C, Vashisht A, Simon S, et al. INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis. Proc Natl Acad Sci U S A. 2012;109:8374-81 pubmed publisher
|
| Saitoh H, Fujisawa S, Mitsuoka C, Ito A, Hirabuchi A, Ikeda K, et al. Large-scale gene disruption in Magnaporthe oryzae identifies MC69, a secreted protein required for infection by monocot and dicot fungal pathogens. PLoS Pathog. 2012;8:e1002711 pubmed publisher
|
| Lacruz R, Nakayama Y, Holcroft J, Nguyen V, Somogyi Ganss E, Snead M, et al. Targeted overexpression of amelotin disrupts the microstructure of dental enamel. PLoS ONE. 2012;7:e35200 pubmed publisher
|
| Leach M, Tyc K, Brown A, Klipp E. Modelling the regulation of thermal adaptation in Candida albicans, a major fungal pathogen of humans. PLoS ONE. 2012;7:e32467 pubmed publisher
|
| Xu G, Liu K, Anderson J, Patrene K, Lentzsch S, Roodman G, et al. Expression of XBP1s in bone marrow stromal cells is critical for myeloma cell growth and osteoclast formation. Blood. 2012;119:4205-14 pubmed publisher
|
| Li R, Wang L, Liao G, Guzzo C, Matunis M, Zhu H, et al. SUMO binding by the Epstein-Barr virus protein kinase BGLF4 is crucial for BGLF4 function. J Virol. 2012;86:5412-21 pubmed publisher
|
| Katsch K, de Jong S, Albrecht J, Steger J, Genth H, Posern G, et al. Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip. Cell Commun Signal. 2012;10:5 pubmed publisher
|
| Zeng X, King R. An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination. Nat Chem Biol. 2012;8:383-92 pubmed publisher
|
| Comas Casellas E, Martinez Barriocanal A, Miro F, Ejarque Ortiz A, Schwartz S, Martin M, et al. Cloning and characterization of CD300d, a novel member of the human CD300 family of immune receptors. J Biol Chem. 2012;287:9682-93 pubmed publisher
|
| Wang Z, Jiang H, Chen S, Du F, Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell. 2012;148:228-43 pubmed publisher
|
| Siaud N, Barbera M, Egashira A, Lam I, Christ N, Schlacher K, et al. Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains. PLoS Genet. 2011;7:e1002409 pubmed publisher
|
| Gregoire I, Richetta C, Meyniel Schicklin L, Borel S, Pradezynski F, Diaz O, et al. IRGM is a common target of RNA viruses that subvert the autophagy network. PLoS Pathog. 2011;7:e1002422 pubmed publisher
|
| Tang X, Seyb K, Huang M, Schuman E, Shi P, Zhu H, et al. A high-throughput screening method for small-molecule inhibitors of the aberrant mutant SOD1 and dynein complex interaction. J Biomol Screen. 2012;17:314-26 pubmed publisher
|
| Lewis E, Wilkinson A, Davis N, Horita D, Wilkinson J. Nondegradative ubiquitination of apoptosis inducing factor (AIF) by X-linked inhibitor of apoptosis at a residue critical for AIF-mediated chromatin degradation. Biochemistry. 2011;50:11084-96 pubmed publisher
|
| Gu X, Jiang D, Yang W, Jacob Y, Michaels S, He Y. Arabidopsis homologs of retinoblastoma-associated protein 46/48 associate with a histone deacetylase to act redundantly in chromatin silencing. PLoS Genet. 2011;7:e1002366 pubmed publisher
|
| Magadán J, Bonifacino J. Transmembrane domain determinants of CD4 Downregulation by HIV-1 Vpu. J Virol. 2012;86:757-72 pubmed publisher
|
| Lukic Z, Hausmann S, Sebastian S, Rucci J, Sastri J, Robia S, et al. TRIM5? associates with proteasomal subunits in cells while in complex with HIV-1 virions. Retrovirology. 2011;8:93 pubmed publisher
|
| Forcales S, Albini S, Giordani L, Malecova B, Cignolo L, Chernov A, et al. Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex. EMBO J. 2012;31:301-16 pubmed publisher
|
| Veeranki S, Duan X, Panchanathan R, Liu H, Choubey D. IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes. PLoS ONE. 2011;6:e27040 pubmed publisher
|
| H sler J, Rada C, Neuberger M. Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1? (eEF1A). Proc Natl Acad Sci U S A. 2011;108:18366-71 pubmed publisher
|
| Bhogal B, Jepson J, Savva Y, Pepper A, Reenan R, Jongens T. Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein. Nat Neurosci. 2011;14:1517-24 pubmed publisher
|
| Burdina A, Klosterman S, Shtessel L, Ahmed S, Richmond J. In vivo analysis of conserved C. elegans tomosyn domains. PLoS ONE. 2011;6:e26185 pubmed publisher
|
| Le Breton M, Meyniel Schicklin L, Deloire A, Coutard B, Canard B, de Lamballerie X, et al. Flavivirus NS3 and NS5 proteins interaction network: a high-throughput yeast two-hybrid screen. BMC Microbiol. 2011;11:234 pubmed publisher
|
| Weterman M, Sorrentino V, Kasher P, Jakobs M, van Engelen B, Fluiter K, et al. A frameshift mutation in LRSAM1 is responsible for a dominant hereditary polyneuropathy. Hum Mol Genet. 2012;21:358-70 pubmed publisher
|
| Schiro M, Stauber S, Peterson T, Krueger C, Darnell S, Satyshur K, et al. Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression. PLoS ONE. 2011;6:e25021 pubmed publisher
|
| Chaudhary S, Pak J, Pedersen B, Bang L, Zhang L, Ngaw S, et al. Efficient expression screening of human membrane proteins in transiently transfected Human Embryonic Kidney 293S cells. Methods. 2011;55:273-80 pubmed publisher
|
| Kerber R, Rieger T, Busch C, Flatz L, Pinschewer D, Kummerer B, et al. Cross-species analysis of the replication complex of Old World arenaviruses reveals two nucleoprotein sites involved in L protein function. J Virol. 2011;85:12518-28 pubmed publisher
|
| Ikeda Kawakatsu K, Maekawa M, Izawa T, Itoh J, Nagato Y. ABERRANT PANICLE ORGANIZATION 2/RFL, the rice ortholog of Arabidopsis LEAFY, suppresses the transition from inflorescence meristem to floral meristem through interaction with APO1. Plant J. 2012;69:168-80 pubmed publisher
|
| Shih J, Wang W, Tsai T, Kuo C, Li H, Wu Lee Y. Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response. Biochem J. 2012;441:119-29 pubmed publisher
|
| Kersse K, Lamkanfi M, Bertrand M, Vanden Berghe T, Vandenabeele P. Interaction patches of procaspase-1 caspase recruitment domains (CARDs) are differently involved in procaspase-1 activation and receptor-interacting protein 2 (RIP2)-dependent nuclear factor ?B signaling. J Biol Chem. 2011;286:35874-82 pubmed publisher
|
| Min T, Kriebel M, Hou S, Pera E. The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo. Dev Biol. 2011;358:262-76 pubmed publisher
|
| Berger E, Crampton M, Nxumalo N, Louw M. Extracellular secretion of a recombinant therapeutic peptide by Bacillus halodurans utilizing a modified flagellin type III secretion system. Microb Cell Fact. 2011;10:62 pubmed publisher
|
| Law J, Vashisht A, Wohlschlegel J, Jacobsen S. SHH1, a homeodomain protein required for DNA methylation, as well as RDR2, RDM4, and chromatin remodeling factors, associate with RNA polymerase IV. PLoS Genet. 2011;7:e1002195 pubmed publisher
|
| Mao X, Gluck N, Chen B, Starokadomskyy P, Li H, Maine G, et al. COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding. J Biol Chem. 2011;286:32355-65 pubmed publisher
|
| Fuchs G, Diges C, Kohlstaedt L, Wehner K, Sarnow P. Proteomic analysis of ribosomes: translational control of mRNA populations by glycogen synthase GYS1. J Mol Biol. 2011;410:118-30 pubmed publisher
|
| Al Madhoun A, Mehta V, Li G, Figeys D, Wiper Bergeron N, Skerjanc I. Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C. EMBO J. 2011;30:2477-89 pubmed publisher
|
| Lee S, Cimica V, Ramachandra N, Zagzag D, Kalpana G. Aurora A is a repressed effector target of the chromatin remodeling protein INI1/hSNF5 required for rhabdoid tumor cell survival. Cancer Res. 2011;71:3225-35 pubmed publisher
|
| Tanaka J, Yanagawa H, Doi N. Comparison of the frequency of functional SH3 domains with different limited sets of amino acids using mRNA display. PLoS ONE. 2011;6:e18034 pubmed publisher
|
| Kim J, Roeder R. Nucleosomal H2B ubiquitylation with purified factors. Methods. 2011;54:331-8 pubmed publisher
|
| Jiang D, Kong N, Gu X, Li Z, He Y. Arabidopsis COMPASS-like complexes mediate histone H3 lysine-4 trimethylation to control floral transition and plant development. PLoS Genet. 2011;7:e1001330 pubmed publisher
|
| Iyengar S, Ivanov A, Jin V, Rauscher F, Farnham P. Functional analysis of KAP1 genomic recruitment. Mol Cell Biol. 2011;31:1833-47 pubmed publisher
|
| Spampanato C, De Leonibus E, Dama P, Gargiulo A, Fraldi A, Sorrentino N, et al. Efficacy of a combined intracerebral and systemic gene delivery approach for the treatment of a severe lysosomal storage disorder. Mol Ther. 2011;19:860-9 pubmed publisher
|
| Boeckel J, Guarani V, Koyanagi M, Roexe T, Lengeling A, Schermuly R, et al. Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1. Proc Natl Acad Sci U S A. 2011;108:3276-81 pubmed publisher
|
| Schaap Nutt A, Higgins C, Amaro Carambot E, Nolan S, D Angelo C, Murphy B, et al. Identification of human parainfluenza virus type 2 (HPIV-2) V protein amino acid residues that reduce binding of V to MDA5 and attenuate HPIV-2 replication in nonhuman primates. J Virol. 2011;85:4007-19 pubmed publisher
|
| Hiragami Hamada K, Shinmyozu K, Hamada D, Tatsu Y, Uegaki K, Fujiwara S, et al. N-terminal phosphorylation of HP1{alpha} promotes its chromatin binding. Mol Cell Biol. 2011;31:1186-200 pubmed publisher
|
| Leach M, Stead D, Argo E, Brown A. Identification of sumoylation targets, combined with inactivation of SMT3, reveals the impact of sumoylation upon growth, morphology, and stress resistance in the pathogen Candida albicans. Mol Biol Cell. 2011;22:687-702 pubmed publisher
|
| Klaus Heisen D, Nurisso A, Pietraszewska Bogiel A, Mbengue M, Camut S, Timmers T, et al. Structure-function similarities between a plant receptor-like kinase and the human interleukin-1 receptor-associated kinase-4. J Biol Chem. 2011;286:11202-10 pubmed publisher
|
| Suzuki T, Maher J, Yamamoto M. Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo. Cancer Res. 2011;71:1700-9 pubmed publisher
|
| Yang L, Katchman A, Morrow J, Doshi D, Marx S. Cardiac L-type calcium channel (Cav1.2) associates with gamma subunits. FASEB J. 2011;25:928-36 pubmed publisher
|
| Cheng C, Gilson T, Dallaire F, Ketner G, Branton P, Blanchette P. The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity. J Virol. 2011;85:765-75 pubmed publisher
|
| Morishita D, Takami M, Yoshikawa S, Katayama R, Sato S, Kukimoto Niino M, et al. Cell-permeable carboxyl-terminal p27(Kip1) peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase. J Biol Chem. 2011;286:2681-8 pubmed publisher
|
| Wei X, Prickett T, Viloria C, Molinolo A, Lin J, Cardenas Navia I, et al. Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma. Mol Cancer Res. 2010;8:1513-25 pubmed publisher
|
| Brunotte L, Lelke M, Hass M, Kleinsteuber K, Becker Ziaja B, G nther S. Domain structure of Lassa virus L protein. J Virol. 2011;85:324-33 pubmed publisher
|
| Pattenden S, Gogol M, Workman J. Features of cryptic promoters and their varied reliance on bromodomain-containing factors. PLoS ONE. 2010;5:e12927 pubmed publisher
|
| Ohashi Y, Munro S. Membrane delivery to the yeast autophagosome from the Golgi-endosomal system. Mol Biol Cell. 2010;21:3998-4008 pubmed publisher
|
| Gilmore Hebert M, Ramabhadran R, Stern D. Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways. Mol Cancer Res. 2010;8:1388-98 pubmed publisher
|
| Qi R, Hoose S, Schreiter J, Sawant K, Lamb R, Ranjith Kumar C, et al. Secretion of the human Toll-like receptor 3 ectodomain is affected by single nucleotide polymorphisms and regulated by Unc93b1. J Biol Chem. 2010;285:36635-44 pubmed publisher
|
| Rorke E, Adhikary G, Jans R, Crish J, Eckert R. AP1 factor inactivation in the suprabasal epidermis causes increased epidermal hyperproliferation and hyperkeratosis but reduced carcinogen-dependent tumor formation. Oncogene. 2010;29:5873-82 pubmed publisher
|
| Hurov K, Cotta Ramusino C, Elledge S. A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability. Genes Dev. 2010;24:1939-50 pubmed publisher
|
| Stepanchick A, McKenna J, McGovern O, Huang Y, Breitwieser G. Calcium sensing receptor mutations implicated in pancreatitis and idiopathic epilepsy syndrome disrupt an arginine-rich retention motif. Cell Physiol Biochem. 2010;26:363-74 pubmed publisher
|
| Ko J, Mitina I, Tamada Y, Hyun Y, Choi Y, Amasino R, et al. Growth habit determination by the balance of histone methylation activities in Arabidopsis. EMBO J. 2010;29:3208-15 pubmed publisher
|
| van Lint A, Murawski M, Goodbody R, Severa M, Fitzgerald K, Finberg R, et al. Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling. J Virol. 2010;84:10802-11 pubmed publisher
|
| Juárez P, Bolás G, de Rezende F, Calvete J, Eble J. Recombinant expression in human cells of active integrin alpha 1 beta 1-blocking RTS-disintegrin jerdostatin. Toxicon. 2010;56:1052-8 pubmed publisher
|
| Chandrasekharan K, Yoon J, Xu Y, DeVries S, Camboni M, Janssen P, et al. A human-specific deletion in mouse Cmah increases disease severity in the mdx model of Duchenne muscular dystrophy. Sci Transl Med. 2010;2:42ra54 pubmed publisher
|
| Jiang H, Jans R, Xu W, Rorke E, Lin C, Chen Y, et al. Type I transglutaminase accumulation in the endoplasmic reticulum may be an underlying cause of autosomal recessive congenital ichthyosis. J Biol Chem. 2010;285:31634-46 pubmed publisher
|
| Earley K, Smith M, Weber R, Gregory B, Poethig R. An endogenous F-box protein regulates ARGONAUTE1 in Arabidopsis thaliana. Silence. 2010;1:15 pubmed publisher
|
| Mackeen M, Kramer H, Chang K, Coleman M, Hopkinson R, Schofield C, et al. Small-molecule-based inhibition of histone demethylation in cells assessed by quantitative mass spectrometry. J Proteome Res. 2010;9:4082-4092 pubmed publisher
|
| Zhou T, Zhang Y, Macchiarulo A, Yang Z, Cellanetti M, Coto E, et al. Novel polymorphisms of nuclear receptor SHP associated with functional and structural changes. J Biol Chem. 2010;285:24871-81 pubmed publisher
|
| Fan W, Tang Z, Chen D, Moughon D, Ding X, Chen S, et al. Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy. Autophagy. 2010;6:614-21 pubmed publisher
|
| Washington A, Singh G, Aiyar A. Diametrically opposed effects of hypoxia and oxidative stress on two viral transactivators. Virol J. 2010;7:93 pubmed publisher
|
| Flowers E, Poole R, Tursun B, Bashllari E, Pe er I, Hobert O. The Groucho ortholog UNC-37 interacts with the short Groucho-like protein LSY-22 to control developmental decisions in C. elegans. Development. 2010;137:1799-805 pubmed publisher
|
| Leech C, Dzhura I, Chepurny O, Schwede F, Genieser H, Holz G. Facilitation of ß-cell K(ATP) channel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac. Islets. 2010;2:72-81 pubmed
|
| Cavanaugh A, McKenna J, Stepanchick A, Breitwieser G. Calcium-sensing receptor biosynthesis includes a cotranslational conformational checkpoint and endoplasmic reticulum retention. J Biol Chem. 2010;285:19854-64 pubmed publisher
|
| Upton J, Kaiser W, Mocarski E. Virus inhibition of RIP3-dependent necrosis. Cell Host Microbe. 2010;7:302-13 pubmed publisher
|
| Mesicek J, Lee H, Feldman T, Jiang X, Skobeleva A, Berdyshev E, et al. Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells. Cell Signal. 2010;22:1300-7 pubmed publisher
|
| Steevels T, Lebbink R, Westerlaken G, Coffer P, Meyaard L. Signal inhibitory receptor on leukocytes-1 is a novel functional inhibitory immune receptor expressed on human phagocytes. J Immunol. 2010;184:4741-8 pubmed publisher
|
| Roth M, Bonev B, Lindsay J, Lea R, Panagiotaki N, Houart C, et al. FoxG1 and TLE2 act cooperatively to regulate ventral telencephalon formation. Development. 2010;137:1553-62 pubmed publisher
|
| Willems S, Tape C, Stanley P, Taylor N, Mills I, Neal D, et al. Thiol isomerases negatively regulate the cellular shedding activity of ADAM17. Biochem J. 2010;428:439-50 pubmed publisher
|
| Krausgruber T, Saliba D, Ryzhakov G, Lanfrancotti A, Blazek K, Udalova I. IRF5 is required for late-phase TNF secretion by human dendritic cells. Blood. 2010;115:4421-30 pubmed publisher
|
| Rasala B, Muto M, Lee P, Jager M, Cardoso R, Behnke C, et al. Production of therapeutic proteins in algae, analysis of expression of seven human proteins in the chloroplast of Chlamydomonas reinhardtii. Plant Biotechnol J. 2010;8:719-33 pubmed publisher
|
| Haussecker D, Huang Y, Lau A, Parameswaran P, Fire A, Kay M. Human tRNA-derived small RNAs in the global regulation of RNA silencing. RNA. 2010;16:673-95 pubmed publisher
|
| Ma Q, Wang J, Liu X, Yang Y, Zhao H, Wang Y, et al. c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3. Cell Death Differ. 2010;17:1277-87 pubmed publisher
|
| Qi X, Wang L, Du F. Novel small molecules relieve prothymosin alpha-mediated inhibition of apoptosome formation by blocking its interaction with Apaf-1. Biochemistry. 2010;49:1923-30 pubmed publisher
|
| Howell K, Arur S, Schedl T, Sundaram M. EOR-2 is an obligate binding partner of the BTB-zinc finger protein EOR-1 in Caenorhabditis elegans. Genetics. 2010;184:899-913 pubmed publisher
|
| Almeida A, Wise H, Hindley C, Slevin M, Hartley R, Philpott A. The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis. Neural Dev. 2010;5:1 pubmed publisher
|
| Jeong J, Song H, Ko J, Jeong Y, Kwon Y, Seol J, et al. Repression of FLOWERING LOCUS T chromatin by functionally redundant histone H3 lysine 4 demethylases in Arabidopsis. PLoS ONE. 2009;4:e8033 pubmed publisher
|
| Carr G, Moochhala S, Eley L, Vandewalle A, Simmons N, Sayer J. The pyrophosphate transporter ANKH is expressed in kidney and bone cells and colocalises to the primary cilium/basal body complex. Cell Physiol Biochem. 2009;24:595-604 pubmed publisher
|
| Goyama S, Nitta E, Yoshino T, Kako S, Watanabe Okochi N, Shimabe M, et al. EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization. Leukemia. 2010;24:81-8 pubmed publisher
|
| Cao D, Haussecker D, Huang Y, Kay M. Combined proteomic-RNAi screen for host factors involved in human hepatitis delta virus replication. RNA. 2009;15:1971-9 pubmed publisher
|
| Gal J, Strom A, Kwinter D, Kilty R, Zhang J, Shi P, et al. Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism. J Neurochem. 2009;111:1062-73 pubmed publisher
|
| Palijan A, Fernandes I, Bastien Y, Tang L, Verway M, Kourelis M, et al. Function of histone deacetylase 6 as a cofactor of nuclear receptor coregulator LCoR. J Biol Chem. 2009;284:30264-74 pubmed publisher
|
| Peck G, Chavez J, Roach W, Budnik B, Lane W, Karlsson H, et al. Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation. J Biol Chem. 2009;284:30016-23 pubmed publisher
|
| Cheng K, Sportoletti P, Ito K, Clohessy J, Teruya Feldstein J, Kutok J, et al. The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model. Blood. 2010;115:3341-5 pubmed publisher
|
| He S, Wang L, Miao L, Wang T, Du F, Zhao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell. 2009;137:1100-11 pubmed publisher
|
| Sorin M, Cano J, Das S, Mathew S, Wu X, Davies K, et al. Recruitment of a SAP18-HDAC1 complex into HIV-1 virions and its requirement for viral replication. PLoS Pathog. 2009;5:e1000463 pubmed publisher
|
| Bookwalter C, Lord M, Trybus K. Essential features of the class V myosin from budding yeast for ASH1 mRNA transport. Mol Biol Cell. 2009;20:3414-21 pubmed publisher
|
| Fu Z, Chen C, Barbieri J, KIM J, Baldwin M. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F. Biochemistry. 2009;48:5631-41 pubmed publisher
|
| Ratnikov B, Cieplak P, Smith J. High throughput substrate phage display for protease profiling. Methods Mol Biol. 2009;539:93-114 pubmed publisher
|
| Mao X, Gluck N, Li D, Maine G, Li H, Zaidi I, et al. GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA. Genes Dev. 2009;23:849-61 pubmed publisher
|
| Webb J, Murányi A, Pugh C, Ratcliffe P, Coleman M. MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH). Biochem J. 2009;420:327-33 pubmed publisher
|
| Chepurny O, Leech C, Kelley G, Dzhura I, Dzhura E, Li X, et al. Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM. J Biol Chem. 2009;284:10728-36 pubmed publisher
|
| Lee J, Mandell E, Tucey T, Morris D, Lundblad V. The Est3 protein associates with yeast telomerase through an OB-fold domain. Nat Struct Mol Biol. 2008;15:990-7 pubmed
|
| Maniccia A, Lewis C, Begum N, Xu J, Cui J, Chipitsyna G, et al. Mitochondrial localization, ELK-1 transcriptional regulation and growth inhibitory functions of BRCA1, BRCA1a, and BRCA1b proteins. J Cell Physiol. 2009;219:634-41 pubmed publisher
|
| Canettieri G, Coni S, Della Guardia M, Nocerino V, Antonucci L, Di Magno L, et al. The coactivator CRTC1 promotes cell proliferation and transformation via AP-1. Proc Natl Acad Sci U S A. 2009;106:1445-50 pubmed publisher
|
| Li M, Shin Y, Hou L, Huang X, Wei Z, Klann E, et al. The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory. Nat Cell Biol. 2008;10:1083-9 pubmed publisher
|
| Meng D, Lynch M, Huston E, Beyermann M, Eichhorst J, Adams D, et al. MEK1 binds directly to betaarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization. J Biol Chem. 2009;284:11425-35 pubmed publisher
|
| Pascreau G, Eckerdt F, Lewellyn A, Prigent C, Maller J. Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes. J Biol Chem. 2009;284:5497-505 pubmed publisher
|
| Wang F, Tong Q. SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma. Mol Biol Cell. 2009;20:801-8 pubmed publisher
|
| Mouilleron S, Guettler S, Langer C, Treisman R, McDonald N. Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL. EMBO J. 2008;27:3198-208 pubmed publisher
|
| Lyons P, Peck G, Kettenbach A, Gerber S, Roudaia L, Lienhard G. Insulin stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes. Biosci Rep. 2009;29:229-35 pubmed publisher
|
| Kaiser W, Upton J, Mocarski E. Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors. J Immunol. 2008;181:6427-34 pubmed
|
| Huber C, Martensson A, Bokoch G, Nemazee D, Gavin A. FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles. J Biol Chem. 2008;283:34002-12 pubmed publisher
|
| Sadaie M, Kawaguchi R, Ohtani Y, Arisaka F, Tanaka K, Shirahige K, et al. Balance between distinct HP1 family proteins controls heterochromatin assembly in fission yeast. Mol Cell Biol. 2008;28:6973-88 pubmed publisher
|
| Maine G, Mao X, Muller P, Komarck C, Klomp L, Burstein E. COMMD1 expression is controlled by critical residues that determine XIAP binding. Biochem J. 2009;417:601-9 pubmed publisher
|
| Haussecker D, Cao D, Huang Y, Parameswaran P, Fire A, Kay M. Capped small RNAs and MOV10 in human hepatitis delta virus replication. Nat Struct Mol Biol. 2008;15:714-21 pubmed publisher
|
| Kurland J, Tansey W. Myc-mediated transcriptional repression by recruitment of histone deacetylase. Cancer Res. 2008;68:3624-9 pubmed publisher
|
| Wang B, Goode J, Best J, Meltzer J, Schilman P, Chen J, et al. The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metab. 2008;7:434-44 pubmed publisher
|
| Ohguchi H, Tanaka T, Uchida A, Magoori K, Kudo H, Kim I, et al. Hepatocyte nuclear factor 4alpha contributes to thyroid hormone homeostasis by cooperatively regulating the type 1 iodothyronine deiodinase gene with GATA4 and Kruppel-like transcription factor 9. Mol Cell Biol. 2008;28:3917-31 pubmed publisher
|
| Dy P, Penzo Méndez A, Wang H, Pedraza C, Macklin W, Lefebvre V. The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Nucleic Acids Res. 2008;36:3101-17 pubmed publisher
|
| Quadrini K, Gruzglin E, Bieker J. Non-random subcellular distribution of variant EKLF in erythroid cells. Exp Cell Res. 2008;314:1595-604 pubmed publisher
|
| Chavez J, Roach W, Keller S, Lane W, Lienhard G. Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation. J Biol Chem. 2008;283:9187-95 pubmed publisher
|
| Van Beekum O, Brenkman A, Grøntved L, Hamers N, van den Broek N, Berger R, et al. The adipogenic acetyltransferase Tip60 targets activation function 1 of peroxisome proliferator-activated receptor gamma. Endocrinology. 2008;149:1840-9 pubmed
|
| Ingvarsdottir K, Edwards C, Lee M, Lee J, Schultz D, Shilatifard A, et al. Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae. Mol Cell Biol. 2007;27:7856-64 pubmed
|
| Copeland S, Green B, Burchat S, Papalia G, Banner D, Copeland J. The diaphanous inhibitory domain/diaphanous autoregulatory domain interaction is able to mediate heterodimerization between mDia1 and mDia2. J Biol Chem. 2007;282:30120-30 pubmed
|
| Hou S, Maccarana M, Min T, Strate I, Pera E. The secreted serine protease xHtrA1 stimulates long-range FGF signaling in the early Xenopus embryo. Dev Cell. 2007;13:226-41 pubmed
|
| Sedore S, Byers S, Biglione S, Price J, Maury W, Price D. Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR. Nucleic Acids Res. 2007;35:4347-58 pubmed
|
| Cheng J, Kydd A, Nakase K, Noonan K, Murakami A, Tao H, et al. Negative regulation of the SH2-homology containing protein-tyrosine phosphatase-1 (SHP-1) P2 promoter by the HTLV-1 Tax oncoprotein. Blood. 2007;110:2110-20 pubmed
|
| Wang F, Nguyen M, Qin F, Tong Q. SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell. 2007;6:505-14 pubmed
|
| Petty A, Garman K, Winn V, Spidel C, Lindsey J. Overexpression of carcinoma and embryonic cytotrophoblast cell-specific Mig-7 induces invasion and vessel-like structure formation. Am J Pathol. 2007;170:1763-80 pubmed
|
| van De Sluis B, Muller P, Duran K, Chen A, Groot A, Klomp L, et al. Increased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null mice. Mol Cell Biol. 2007;27:4142-56 pubmed
|
| Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher J, Ohta T, et al. Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes. Biochem J. 2007;404:459-66 pubmed
|
| Roach W, Chavez J, Miinea C, Lienhard G. Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1. Biochem J. 2007;403:353-8 pubmed
|
| Bhattacharyya D, Glick B. Two mammalian Sec16 homologues have nonredundant functions in endoplasmic reticulum (ER) export and transitional ER organization. Mol Biol Cell. 2007;18:839-49 pubmed
|
| Serra H, Duvick L, Zu T, Carlson K, Stevens S, Jorgensen N, et al. RORalpha-mediated Purkinje cell development determines disease severity in adult SCA1 mice. Cell. 2006;127:697-708 pubmed
|
| Quadrini K, Bieker J. EKLF/KLF1 is ubiquitinated in vivo and its stability is regulated by activation domain sequences through the 26S proteasome. FEBS Lett. 2006;580:2285-93 pubmed
|
| Pavoni E, Flego M, Dupuis M, Barca S, Petronzelli F, Anastasi A, et al. Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein. BMC Cancer. 2006;6:41 pubmed
|
| Guerzoni C, Bardini M, Mariani S, Ferrari Amorotti G, Neviani P, Panno M, et al. Inducible activation of CEBPB, a gene negatively regulated by BCR/ABL, inhibits proliferation and promotes differentiation of BCR/ABL-expressing cells. Blood. 2006;107:4080-9 pubmed
|
| Jin Y, Cao C, Li P, Liu X, Huang W, Li C, et al. Boosting immune response to hepatitis B DNA vaccine by coadministration of Prothymosin alpha-expressing plasmid. Clin Diagn Lab Immunol. 2005;12:1364-9 pubmed
|
| Regala R, Weems C, Jamieson L, Copland J, Thompson E, Fields A. Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity. J Biol Chem. 2005;280:31109-15 pubmed
|
| Chen J, Wu A, Sun H, Drakas R, Garofalo C, Cascio S, et al. Functional significance of type 1 insulin-like growth factor-mediated nuclear translocation of the insulin receptor substrate-1 and beta-catenin. J Biol Chem. 2005;280:29912-20 pubmed
|
| Westbrook T, Martin E, Schlabach M, Leng Y, Liang A, Feng B, et al. A genetic screen for candidate tumor suppressors identifies REST. Cell. 2005;121:837-48 pubmed
|
| Ziogas A, Moelling K, Radziwill G. CNK1 is a scaffold protein that regulates Src-mediated Raf-1 activation. J Biol Chem. 2005;280:24205-11 pubmed
|
| Burstein E, Hoberg J, Wilkinson A, Rumble J, Csomos R, Komarck C, et al. COMMD proteins, a novel family of structural and functional homologs of MURR1. J Biol Chem. 2005;280:22222-32 pubmed
|
| Tian B, Nowak D, Jamaluddin M, Wang S, Brasier A. Identification of direct genomic targets downstream of the nuclear factor-kappaB transcription factor mediating tumor necrosis factor signaling. J Biol Chem. 2005;280:17435-48 pubmed
|
| Stewart T, Wasilenko S, Barry M. Vaccinia virus F1L protein is a tail-anchored protein that functions at the mitochondria to inhibit apoptosis. J Virol. 2005;79:1084-98 pubmed
|
| Alderson N, Rembiesa B, Walla M, Bielawska A, Bielawski J, Hama H. The human FA2H gene encodes a fatty acid 2-hydroxylase. J Biol Chem. 2004;279:48562-8 pubmed
|
| Xu X, Lee J, Stern D. Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. J Biol Chem. 2004;279:34091-4 pubmed
|
| Nishizawa H, Matsuda M, Yamada Y, Kawai K, Suzuki E, Makishima M, et al. Musclin, a novel skeletal muscle-derived secretory factor. J Biol Chem. 2004;279:19391-5 pubmed
|
| Burstein E, Ganesh L, Dick R, van De Sluis B, Wilkinson J, Klomp L, et al. A novel role for XIAP in copper homeostasis through regulation of MURR1. EMBO J. 2004;23:244-54 pubmed
|
| Efimova T, Deucher A, Kuroki T, Ohba M, Eckert R. Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38 delta mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha. J Biol Chem. 2002;277:31753-60 pubmed
|
| Tian B, Zhang Y, Luxon B, Garofalo R, Casola A, Sinha M, et al. Identification of NF-kappaB-dependent gene networks in respiratory syncytial virus-infected cells. J Virol. 2002;76:6800-14 pubmed
|
| Miret J, Rakhilina L, Silverman L, Oehlen B. Functional expression of heteromeric calcitonin gene-related peptide and adrenomedullin receptors in yeast. J Biol Chem. 2002;277:6881-7 pubmed
|
| Dashti S, Efimova T, Eckert R. MEK6 regulates human involucrin gene expression via a p38alpha - and p38delta -dependent mechanism. J Biol Chem. 2001;276:27214-20 pubmed
|