product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-α-Amylase antibody produced in rabbit
catalog :
A8273
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 38
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1b
Wen H, Gao S, Wang Y, Ray M, Magnuson M, Wright C, et al. Myeloid cell-derived HB-EGF Drives Tissue Recovery After Pancreatitis. Cell Mol Gastroenterol Hepatol. 2019;: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 1d
Wang S, Ni H, Chao X, Wang H, Bridges B, Kumer S, et al. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis. Autophagy. 2019;15:1954-1969 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1d
Halbrook C, Wen H, Ruggeri J, Takeuchi K, Zhang Y, di Magliano M, et al. Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis. Cell Mol Gastroenterol Hepatol. 2017;3:99-118 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig s1
Zhang Y, Velez Delgado A, Mathew E, Li D, Mendez F, Flannagan K, et al. Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer. Gut. 2017;66:124-136 pubmed publisher
  • immunocytochemistry; human; fig 9
  • western blot; human; fig 7
Maria O, Liu Y, El Hakim M, Zeitouni A, Tran S. The role of human fibronectin- or placenta basement membrane extract-based gels in favouring the formation of polarized salivary acinar-like structures. J Tissue Eng Regen Med. 2017;11:2643-2657 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig s2
Zhang Q, Zhang Y, Parsels J, Lohse I, Lawrence T, Pasca di Magliano M, et al. Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation. Neoplasia. 2016;18:666-673 pubmed publisher
  • immunocytochemistry; mouse; fig s4c
  • western blot; mouse; loading ...; fig s4b
Lesina M, Wörmann S, Morton J, Diakopoulos K, Korneeva O, Wimmer M, et al. RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis. J Clin Invest. 2016;126:2919-32 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 3a
Omori H, Ogaki S, Sakano D, Sato M, Umeda K, Takeda N, et al. Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development. FEBS Lett. 2016;590:2584-93 pubmed publisher
Bray J, Elgamal O, Jiang J, Wright L, Sutaria D, Badawi M, et al. Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury. Cell Death Dis. 2020;11:138 pubmed publisher
Xia D, Halder B, Godoy C, Chakraborty A, Singla B, Thomas E, et al. NADPH oxidase 1 mediates caerulein-induced pancreatic fibrosis in chronic pancreatitis. Free Radic Biol Med. 2020;147:139-149 pubmed publisher
Chen C, Shiota C, Agostinelli G, Ridley D, Jiang Y, Ma J, et al. Evidence of a developmental origin of beta-cell heterogeneity using a dual lineage tracing technology. Development. 2019;: pubmed publisher
Lee H, Lee J, Lee J, Kim E, Kim H, Chung M, et al. Establishment of pancreatic cancer cell lines with endoscopic ultrasound-guided biopsy via conditionally reprogrammed cell culture. Cancer Med. 2019;8:3339-3348 pubmed publisher
Lee K, Kim H, Lee J, Oh C, Song H, Kim H, et al. Essential Role of Protein Arginine Methyltransferase 1 in Pancreas Development by Regulating Protein Stability of Neurogenin 3. Diabetes Metab J. 2019;43:649-658 pubmed publisher
Giannios I, Serafimidis I, Anastasiou V, Pezzolla D, Lesche M, Andree C, et al. Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression. Stem Cells. 2019;37:640-651 pubmed publisher
Scavuzzo M, Chmielowiec J, Yang D, Wamble K, Chaboub L, Duraine L, et al. Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA. Cell Rep. 2018;25:3811-3827.e7 pubmed publisher
Livshits G, Alonso Curbelo D, Morris J, Koche R, Saborowski M, Wilkinson J, et al. Arid1a restrains Kras-dependent changes in acinar cell identity. elife. 2018;7: pubmed publisher
Rybová J, Kuchar L, Hulkova H, Asfaw B, Dobrovolny R, Sikora J, et al. Specific storage of glycoconjugates with terminal α-galactosyl moieties in the exocrine pancreas of Fabry disease patients with blood group B. Glycobiology. 2018;28:382-391 pubmed publisher
Elenbaas J, Bragazzi Cunha J, Azuero Dajud R, Nelson B, Oral E, Williams J, et al. Lamin A/C Maintains Exocrine Pancreas Homeostasis by Regulating Stability of RB and Activity of E2F. Gastroenterology. 2018;154:1625-1629.e8 pubmed publisher
Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle N, et al. Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas. Cancer Cell. 2017;32:824-839.e8 pubmed publisher
Murai N, Ohtaki H, Watanabe J, Xu Z, Sasaki S, Yagura K, et al. Intrapancreatic injection of human bone marrow-derived mesenchymal stem/stromal cells alleviates hyperglycemia and modulates the macrophage state in streptozotocin-induced type 1 diabetic mice. PLoS ONE. 2017;12:e0186637 pubmed publisher
Lugea A, Waldron R, Mareninova O, Shalbueva N, Deng N, Su H, et al. Human Pancreatic Acinar Cells: Proteomic Characterization, Physiologic Responses, and Organellar Disorders in ex Vivo Pancreatitis. Am J Pathol. 2017;187:2726-2743 pubmed publisher
Chang H, Moro A, Takakura K, Su H, Mo A, Nakanishi M, et al. Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice. PLoS ONE. 2017;12:e0184455 pubmed publisher
Scavuzzo M, Yang D, Borowiak M. Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells. Sci Rep. 2017;7:10810 pubmed publisher
Zaytouni T, Tsai P, Hitchcock D, DuBois C, Freinkman E, Lin L, et al. Critical role for arginase 2 in obesity-associated pancreatic cancer. Nat Commun. 2017;8:242 pubmed publisher
Zhao M, Rabieifar P, Costa T, Zhuang T, Minden A, Lohr M, et al. Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development. Sci Rep. 2017;7:7031 pubmed publisher
Chuvin N, Vincent D, Pommier R, Alcaraz L, Gout J, Caligaris C, et al. Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRASG12D-driven Pancreatic Tumorigenesis. Cell Mol Gastroenterol Hepatol. 2017;4:263-282 pubmed publisher
Watanabe H, Takahashi H, Hata Kawakami M, Tanaka A. Expression of c-kit and Cytokeratin 5 in the Submandibular Gland after Release of Long-Term Ligation of the Main Excretory Duct in Mice. Acta Histochem Cytochem. 2017;50:111-118 pubmed publisher
Khoriaty R, Vogel N, Hoenerhoff M, Sans M, Zhu G, Everett L, et al. SEC23B is required for pancreatic acinar cell function in adult mice. Mol Biol Cell. 2017;28:2146-2154 pubmed publisher
Kondo Y, Toyoda T, Ito R, Funato M, Hosokawa Y, Matsui S, et al. Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells. Diabetologia. 2017;60:1454-1466 pubmed publisher
Ball C, Oppel F, Ehrenberg K, Dubash T, Dieter S, Hoffmann C, et al. Succession of transiently active tumor-initiating cell clones in human pancreatic cancer xenografts. EMBO Mol Med. 2017;9:918-932 pubmed publisher
van Arensbergen J, Dussaud S, Pardanaud Glavieux C, García Hurtado J, Sauty C, Guerci A, et al. A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element. PLoS ONE. 2017;12:e0171508 pubmed publisher
Qu X, Nyeng P, Xiao F, Dorantes J, Jensen J. Growth Factor Independence-1 (Gfi1) Is Required for Pancreatic Acinar Unit Formation and Centroacinar Cell Differentiation. Cell Mol Gastroenterol Hepatol. 2015;1:233-247.e1 pubmed publisher
Bhat N, Park J, Zoghbi H, Arthur J, Zaret K. The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development. PLoS ONE. 2016;11:e0166703 pubmed publisher
Hibsher D, Epshtein A, Oren N, Landsman L. Pancreatic Mesenchyme Regulates Islet Cellular Composition in a Patched/Hedgehog-Dependent Manner. Sci Rep. 2016;6:38008 pubmed publisher
Mfopou J, Houbracken I, Wauters E, Mathijs I, Song I, Himpe E, et al. Acinar phenotype is preserved in human exocrine pancreas cells cultured at low temperature: implications for lineage-tracing of β-cell neogenesis. Biosci Rep. 2016;36: pubmed publisher
Bradford E, Vairamani K, Shull G. Differential expression of pancreatic protein and chemosensing receptor mRNAs in NKCC1-null intestine. World J Gastrointest Pathophysiol. 2016;7:138-49 pubmed publisher
Eisses J, Criscimanna A, Dionise Z, Orabi A, Javed T, Sarwar S, et al. Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs. Am J Pathol. 2015;185:3304-15 pubmed publisher
Song I, Patel O, Himpe E, Muller C, Bouwens L. Beta Cell Mass Restoration in Alloxan-Diabetic Mice Treated with EGF and Gastrin. PLoS ONE. 2015;10:e0140148 pubmed publisher
product information
Catalog Number :
A8273
Product Name :
Anti-α-Amylase antibody produced in rabbit
Product Type :
ANTIBODIES - SIAL
Product Group :
Protein & Pathway Technologies
Host Species :
rabbit
Clonality :
polyclonal
Conjugation :
unconjugated
Product Description :
fractionated antiserum, lyophilized powder
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA