Chen 陈温纯 W, Voos K, Josephson C, Li R. Short-Acting Anti-VWF (von Willebrand Factor) Aptamer Improves the Recovery, Survival, and Hemostatic Functions of Refrigerated Platelets. Arterioscler Thromb Vasc Biol. 2019;39:2028-2037 pubmed publisher

Aurbach K, Spindler M, Haining E, Bender M, Pleines I. Blood collection, platelet isolation and measurement of platelet count and size in mice-a practical guide. Platelets. 2019;30:698-707 pubmed publisher

Preston G, Guerriero C, Metzger M, Michaelis S, Brodsky J. Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic-Reticulum-Associated Degradation. Mol Cell. 2018;70:242-253.e6 pubmed publisher

Madry C, Arancibia Carcamo I, Kyrargyri V, Chan V, Hamilton N, Attwell D. Effects of the ecto-ATPase apyrase on microglial ramification and surveillance reflect cell depolarization, not ATP depletion. Proc Natl Acad Sci U S A. 2018;115:E1608-E1617 pubmed publisher

Horton S, Luna Lopez C, Blevins E, Howarth H, Weisberg J, Shestopalov V, et al. Pannexin 1 Modulates Axonal Growth in Mouse Peripheral Nerves. Front Cell Neurosci. 2017;11:365 pubmed publisher

Handly L, Wollman R. Wound-induced Ca2+ wave propagates through a simple release and diffusion mechanism. Mol Biol Cell. 2017;28:1457-1466 pubmed publisher

Kaku H, Cheng K, Al Abed Y, Rothstein T. A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production. J Immunol. 2014;193:5904-13 pubmed publisher

Gao Y, Cao J, Li P, Huang G, Yang J. Th2 cytokine-primed airway smooth muscle cells induce mast cell chemotaxis via secretion of ATP. J Asthma. 2014;51:997-1003 pubmed publisher

Bai A, Moss A, Kokkotou E, Usheva A, Sun X, Cheifetz A, et al. CD39 and CD161 modulate Th17 responses in Crohn's disease. J Immunol. 2014;193:3366-77 pubmed publisher

Herrath J, Chemin K, Albrecht I, Catrina A, Malmstrom V. Surface expression of CD39 identifies an enriched Treg-cell subset in the rheumatic joint, which does not suppress IL-17A secretion. Eur J Immunol. 2014;44:2979-89 pubmed publisher

Gershwin M, Krawitt E. Autoimmune hepatitis: 50 Years of (slow) progress. Hepatology. 2014;59:754-6 pubmed

Silva Pinto A, Dias Carlos C, Saldanha Araujo F, Ferreira F, Palma P, Araújo A, et al. Hydroxycarbamide modulates components involved in the regulation of adenosine levels in blood cells from sickle-cell anemia patients. Ann Hematol. 2014;93:1457-65 pubmed publisher

Dulphy N, Henry G, Hemon P, Khaznadar Z, Dombret H, Boissel N, et al. Contribution of CD39 to the immunosuppressive microenvironment of acute myeloid leukaemia at diagnosis. Br J Haematol. 2014;165:722-5 pubmed publisher

Imanguli M, Cowen E, Rose J, Dhamala S, Swaim W, Lafond S, et al. Comparative analysis of FoxP3(+) regulatory T cells in the target tissues and blood in chronic graft versus host disease. Leukemia. 2014;28:2016-27 pubmed publisher

Thiolat A, Semerano L, Pers Y, Biton J, Lemeiter D, Portales P, et al. Interleukin-6 receptor blockade enhances CD39+ regulatory T cell development in rheumatoid arthritis and in experimental arthritis. Arthritis Rheumatol. 2014;66:273-83 pubmed publisher

Han J, Patterson S, Speck M, Ehses J, Levings M. Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity. J Immunol. 2014;192:623-9 pubmed publisher

Jie H, Gildener Leapman N, Li J, Srivastava R, Gibson S, Whiteside T, et al. Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients. Br J Cancer. 2013;109:2629-35 pubmed publisher

Lee D, Taylor A. Both MC5r and A2Ar are required for protective regulatory immunity in the spleen of post-experimental autoimmune uveitis in mice. J Immunol. 2013;191:4103-11 pubmed publisher

Mascanfroni I, Yeste A, Vieira S, Burns E, Patel B, Sloma I, et al. IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat Immunol. 2013;14:1054-63 pubmed publisher

Younas M, Hue S, Lacabaratz C, Guguin A, Wiedemann A, Surenaud M, et al. IL-7 modulates in vitro and in vivo human memory T regulatory cell functions through the CD39/ATP axis. J Immunol. 2013;191:3161-8 pubmed publisher

Govindaraj C, Scalzo Inguanti K, Madondo M, Hallo J, Flanagan K, Quinn M, et al. Impaired Th1 immunity in ovarian cancer patients is mediated by TNFR2+ Tregs within the tumor microenvironment. Clin Immunol. 2013;149:97-110 pubmed publisher

Shrivastava A, Kowalewski J, Renner M, Bousset L, Koulakoff A, Melki R, et al. ?-amyloid and ATP-induced diffusional trapping of astrocyte and neuronal metabotropic glutamate type-5 receptors. Glia. 2013;61:1673-86 pubmed publisher

MacCarthy C, Notario V. The ENTPD5/mt-PCPH oncoprotein is a catalytically inactive member of the ectonucleoside triphosphate diphosphohydrolase family. Int J Oncol. 2013;43:1244-52 pubmed publisher

Cohen H, Briggs K, Marino J, Ravid K, Robson S, Mosser D. TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses. Blood. 2013;122:1935-45 pubmed publisher

Baek A, Kanthi Y, Sutton N, Liao H, Pinsky D. Regulation of ecto-apyrase CD39 (ENTPD1) expression by phosphodiesterase III (PDE3). FASEB J. 2013;27:4419-28 pubmed publisher

Pluskota E, Ma Y, Bledzka K, Bialkowska K, Soloviev D, Szpak D, et al. Kindlin-2 regulates hemostasis by controlling endothelial cell-surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism. Blood. 2013;122:2491-9 pubmed publisher

Otsuka A, Hanakawa S, Miyachi Y, Kabashima K. CD39: a new surface marker of mouse regulatory ?? T cells. J Allergy Clin Immunol. 2013;132:1448-51 pubmed publisher

Cecati M, Emanuelli M, Giannubilo S, Quarona V, Senetta R, Malavasi F, et al. Contribution of adenosine-producing ectoenzymes to the mechanisms underlying the mitigation of maternal-fetal conflicts. J Biol Regul Homeost Agents. 2013;27:519-29 pubmed

Yoshida O, Kimura S, Jackson E, Robson S, Geller D, Murase N, et al. CD39 expression by hepatic myeloid dendritic cells attenuates inflammation in liver transplant ischemia-reperfusion injury in mice. Hepatology. 2013;58:2163-75 pubmed publisher

Gullo F, De Bari C. Prospective purification of a subpopulation of human synovial mesenchymal stem cells with enhanced chondro-osteogenic potency. Rheumatology (Oxford). 2013;52:1758-68 pubmed publisher

Abdalla F, Cardoso A, Pereira L, Schmatz R, Gonçalves J, Stefanello N, et al. Neuroprotective effect of quercetin in ectoenzymes and acetylcholinesterase activities in cerebral cortex synaptosomes of cadmium-exposed rats. Mol Cell Biochem. 2013;381:1-8 pubmed

Hughes A. Evolution of the salivary apyrases of blood-feeding arthropods. Gene. 2013;527:123-30 pubmed publisher

Grant C, Liberal R, Holder B, Cardone J, Ma Y, Robson S, et al. Dysfunctional CD39(POS) regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis. Hepatology. 2014;59:1007-15 pubmed publisher

Xu S, Shao Q, Sun J, Yang N, Xie Q, Wang D, et al. Synergy between the ectoenzymes CD39 and CD73 contributes to adenosinergic immunosuppression in human malignant gliomas. Neuro Oncol. 2013;15:1160-72 pubmed publisher

Saze Z, Schuler P, Hong C, Cheng D, Jackson E, Whiteside T. Adenosine production by human B cells and B cell-mediated suppression of activated T cells. Blood. 2013;122:9-18 pubmed publisher

Lu D, Insel P. Hydrolysis of extracellular ATP by ectonucleoside triphosphate diphosphohydrolase (ENTPD) establishes the set point for fibrotic activity of cardiac fibroblasts. J Biol Chem. 2013;288:19040-9 pubmed publisher

Wujak M, Banach M, Porowińska D, Piskulak K, Komoszyński M. Isolation and bioinformatic analysis of seven genes encoding potato apyrase. Bacterial overexpresssion, refolding and initial kinetic studies on some recombinant potato apyrases. Phytochemistry. 2013;93:8-17 pubmed publisher

Boer M, van Meijgaarden K, Bastid J, Ottenhoff T, Joosten S. CD39 is involved in mediating suppression by Mycobacterium bovis BCG-activated human CD8(+) CD39(+) regulatory T cells. Eur J Immunol. 2013;43:1925-32 pubmed publisher

Newman D. CD39 target practice. Blood. 2013;121:3061-2 pubmed publisher

Takahashi T, Kimura Y, Niwa K, Ohmiya Y, Fujimura T, Yamasaki K, et al. In vivo imaging demonstrates ATP release from murine keratinocytes and its involvement in cutaneous inflammation after tape stripping. J Invest Dermatol. 2013;133:2407-2415 pubmed publisher

Zebisch M, Schäfer P, Lauble P, Strater N. New crystal forms of NTPDase1 from the bacterium Legionella pneumophila. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013;69:257-62 pubmed publisher

Schmelzle M, Duhme C, Junger W, Salhanick S, Chen Y, Wu Y, et al. CD39 modulates hematopoietic stem cell recruitment and promotes liver regeneration in mice and humans after partial hepatectomy. Ann Surg. 2013;257:693-701 pubmed publisher

Idzko M, K Ayata C, Müller T, Dürk T, Grimm M, Baudiß K, et al. Attenuated allergic airway inflammation in Cd39 null mice. Allergy. 2013;68:472-80 pubmed publisher

Cui M, Bai X, Li T, Chen F, Dong Q, Zhao Y, et al. Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. PLoS ONE. 2013;8:e57065 pubmed publisher

Leal F, Ndhlovu L, Hasenkrug A, Bruno F, Carvalho K, Wynn Williams H, et al. Expansion in CD39⁺ CD4⁺ immunoregulatory t cells and rarity of Th17 cells in HTLV-1 infected patients is associated with neurological complications. PLoS Negl Trop Dis. 2013;7:e2028 pubmed publisher

Chen M, Su W, Lin X, Guo Z, Wang J, Zhang Q, et al. Adoptive transfer of human gingiva-derived mesenchymal stem cells ameliorates collagen-induced arthritis via suppression of Th1 and Th17 cells and enhancement of regulatory T cell differentiation. Arthritis Rheum. 2013;65:1181-93 pubmed publisher

Hohmann J, Wang X, Krajewski S, Selan C, Haller C, Straub A, et al. Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?. Blood. 2013;121:3067-75 pubmed publisher

Chia J, McRae J, Thomas H, Fynch S, Elkerbout L, Hill P, et al. The protective effects of CD39 overexpression in multiple low-dose streptozotocin-induced diabetes in mice. Diabetes. 2013;62:2026-35 pubmed publisher

Yu W, Sun X, Robson S, Hill W. Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway. FASEB J. 2013;27:1895-903 pubmed publisher

Himmel M, Macdonald K, Garcia R, Steiner T, Levings M. Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans. J Immunol. 2013;190:2001-8 pubmed publisher

Parodi A, Battaglia F, Kalli F, Ferrera F, Conteduca G, Tardito S, et al. CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes. Cancer Immunol Immunother. 2013;62:851-62 pubmed publisher

Nowak Machen M, Schmelzle M, Hanidziar D, Junger W, Exley M, Otterbein L, et al. Pulmonary natural killer T cells play an essential role in mediating hyperoxic acute lung injury. Am J Respir Cell Mol Biol. 2013;48:601-9 pubmed publisher

Teramura Y, Oommen O, Olerud J, Hilborn J, Nilsson B. Microencapsulation of cells, including islets, within stable ultra-thin membranes of maleimide-conjugated PEG-lipid with multifunctional crosslinkers. Biomaterials. 2013;34:2683-93 pubmed publisher

Schmelzle M, Splith K, Andersen L, Kornek M, Schuppan D, Jones Bamman C, et al. Increased plasma levels of microparticles expressing CD39 and CD133 in acute liver injury. Transplantation. 2013;95:63-9 pubmed publisher

Regateiro F, Cobbold S, Waldmann H. CD73 and adenosine generation in the creation of regulatory microenvironments. Clin Exp Immunol. 2013;171:1-7 pubmed publisher

Roberts N, Morieri G, Kalsi G, Rose A, Stiller J, Edwards A, et al. Rhizobial and mycorrhizal symbioses in Lotus japonicus require lectin nucleotide phosphohydrolase, which acts upstream of calcium signaling. Plant Physiol. 2013;161:556-67 pubmed publisher

Chia J, McRae J, Cowan P, Dwyer K. The CD39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes. J Biomed Biotechnol. 2012;2012:320495 pubmed publisher

Martin F, Apetoh L, Ghiringhelli F. Controversies on the role of Th17 in cancer: a TGF-?-dependent immunosuppressive activity?. Trends Mol Med. 2012;18:742-9 pubmed publisher

Kumar N, Cherkas P, Chiang C, Dostrovsky J, Sessle B, Coderre T. Involvement of ATP in noxious stimulus-evoked release of glutamate in rat medullary dorsal horn: a microdialysis study. Neurochem Int. 2012;61:1276-9 pubmed publisher

Liu X, Wu J, Clark G, Lundy S, Lim M, Arnold D, et al. Role for apyrases in polar auxin transport in Arabidopsis. Plant Physiol. 2012;160:1985-95 pubmed publisher

Bushart T, Cannon A, ul Haque A, San Miguel P, Mostajeran K, Clark G, et al. RNA-seq analysis identifies potential modulators of gravity response in spores of Ceratopteris (Parkeriaceae): evidence for modulation by calcium pumps and apyrase activity. Am J Bot. 2013;100:161-74 pubmed publisher

Chevalier M, Weiss L. The split personality of regulatory T cells in HIV infection. Blood. 2013;121:29-37 pubmed publisher

Chiu T, Christiansen K, Moreno I, Lao J, Loque D, Orellana A, et al. AtAPY1 and AtAPY2 function as Golgi-localized nucleoside diphosphatases in Arabidopsis thaliana. Plant Cell Physiol. 2012;53:1913-25 pubmed publisher

Wu J, Li G, Luna C, Spasojevic I, Epstein D, Gonzalez P. Endogenous production of extracellular adenosine by trabecular meshwork cells: potential role in outflow regulation. Invest Ophthalmol Vis Sci. 2012;53:7142-8 pubmed publisher

Maia A, Porcino G, Detoni M, Emídio N, Marconato D, Faria Pinto P, et al. An antigenic domain within a catalytically active Leishmania infantum nucleoside triphosphate diphosphohydrolase (NTPDase 1) is a target of inhibitory antibodies. Parasitol Int. 2013;62:44-52 pubmed publisher

Milosević M, Petrović S, Velickovic N, Grković I, Ignjatović M, Horvat A. ATP and ADP hydrolysis in cell membranes from rat myometrium. Mol Cell Biochem. 2012;371:199-208 pubmed publisher

Rooklin D, Lu M, Zhang Y. Revelation of a catalytic calcium-binding site elucidates unusual metal dependence of a human apyrase. J Am Chem Soc. 2012;134:15595-603 pubmed

Porcino G, Carvalho Campos C, Maia A, Detoni M, Faria Pinto P, Coimbra E, et al. Leishmania (Viannia) braziliensis nucleoside triphosphate diphosphohydrolase (NTPDase 1): localization and in vitro inhibition of promastigotes growth by polyclonal antibodies. Exp Parasitol. 2012;132:293-9 pubmed publisher

Zhang Y, Wang Y, Zong H, Yang C. A study of the imbalance in B cell-expressed nucleoside triphosphate diphosphohydrolase 1-induced ADP degradation in graft injury during acute antibody-mediated rejection. Transpl Immunol. 2012;27:175-8 pubmed publisher

Butovsky O, Siddiqui S, Gabriely G, Lanser A, Dake B, Murugaiyan G, et al. Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS. J Clin Invest. 2012;122:3063-87 pubmed publisher

Schuster M, Treitschke S, Kilaru S, Molloy J, Harmer N, Steinberg G. Myosin-5, kinesin-1 and myosin-17 cooperate in secretion of fungal chitin synthase. EMBO J. 2012;31:214-27 pubmed publisher

Paruchuri S, Tashimo H, Feng C, Maekawa A, Xing W, Jiang Y, et al. Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor. J Exp Med. 2009;206:2543-55 pubmed publisher

Weerasinghe R, Swanson S, Okada S, Garrett M, Kim S, Stacey G, et al. Touch induces ATP release in Arabidopsis roots that is modulated by the heterotrimeric G-protein complex. FEBS Lett. 2009;583:2521-6 pubmed publisher

Gontan C, Guttler T, Engelen E, Demmers J, Fornerod M, Grosveld F, et al. Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. J Cell Biol. 2009;185:27-34 pubmed publisher

Bianco F, Colombo A, Saglietti L, Lecca D, Abbracchio M, Matteoli M, et al. Different properties of P2X(7) receptor in hippocampal and cortical astrocytes. Purinergic Signal. 2009;5:233-40 pubmed publisher

Kaufmann T, Jost P, Pellegrini M, Puthalakath H, Gugasyan R, Gerondakis S, et al. Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim. Immunity. 2009;30:56-66 pubmed publisher

Iwai S, Uyeda T. Visualizing myosin-actin interaction with a genetically-encoded fluorescent strain sensor. Proc Natl Acad Sci U S A. 2008;105:16882-7 pubmed publisher

Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, Onoue M, et al. ATP drives lamina propria T(H)17 cell differentiation. Nature. 2008;455:808-12 pubmed publisher

Riewe D, Grosman L, Fernie A, Wucke C, Geigenberger P. The potato-specific apyrase is apoplastically localized and has influence on gene expression, growth, and development. Plant Physiol. 2008;147:1092-109 pubmed publisher

Krishnan P. Apyrase, pyrophosphatase and metaphosphatase of Penicillium chrysogenum. Arch Biochem Biophys. 1952;37:224-34 pubmed

Liebecq C, Lallemand A, DEGUELDRE GUILLAUME M. [Partial purification and properties of potato apyrase]. Bull Soc Chim Biol (Paris). 1963;45:573-94 pubmed

Bastida E, Ordinas A, Giardina S, Jamieson G. Differentiation of platelet-aggregating effects of human tumor cell lines based on inhibition studies with apyrase, hirudin, and phospholipase. Cancer Res. 1982;42:4348-52 pubmed