This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Methotrexate hydrate
catalog :
A6770
citations: 180
Reference
Schmidt O, Weyer Y, Baumann V, Widerin M, Eising S, Angelova M, et al. Endosome and Golgi-associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism. EMBO J. 2019;38:e101433 pubmed publisher
Mensah E, Guo X, Gao X, Fujita M. Establishment of DHFR-deficient HEK293 cells for high yield of therapeutic glycoproteins. J Biosci Bioeng. 2019;: pubmed publisher
Hajian B, Scocchera E, Shoen C, Krucinska J, Viswanathan K, G Dayanandan N, et al. Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents. Cell Chem Biol. 2019;26:781-791.e6 pubmed publisher
Albrecht L, Bui M, De Robertis E. Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation. Proc Natl Acad Sci U S A. 2019;116:2987-2995 pubmed publisher
Sachs N, Papaspyropoulos A, Zomer van Ommen D, Heo I, Böttinger L, Klay D, et al. Long-term expanding human airway organoids for disease modeling. EMBO J. 2019;38: pubmed publisher
Alata Jimenez N, Torres Pérez S, Sánchez Vásquez E, Fernandino J, Strobl Mazzulla P. Folate deficiency prevents neural crest fate by disturbing the epigenetic Sox2 repression on the dorsal neural tube. Dev Biol. 2018;444 Suppl 1:S193-S201 pubmed publisher
Tanimoto A, Shinozaki Y, Nozawa K, Kimoto Y, Amano W, Matsuo A, et al. Improvement of spontaneous locomotor activity with JAK inhibition by JTE-052 in rat adjuvant-induced arthritis. BMC Musculoskelet Disord. 2015;16:339 pubmed publisher
Salva K, Wood G. Epigenetically Enhanced Photodynamic Therapy (ePDT) is Superior to Conventional Photodynamic Therapy for Inducing Apoptosis in Cutaneous T-Cell Lymphoma. Photochem Photobiol. 2015;91:1444-51 pubmed publisher
Chen X, Hansen D, Merry G, DeJarnette C, Nolen G, Sloper D, et al. Developing osteoblasts as an endpoint for the mouse embryonic stem cell test. Reprod Toxicol. 2015;53:131-40 pubmed publisher
Emery P, Hammoudeh M, Combe B. Etanercept tapering in rheumatoid arthritis. N Engl J Med. 2015;372:489-90 pubmed publisher
Patel S, Kusano A, Truong A, Stelzer K, Laramore G. Fast neutron radiotherapy in the treatment of malignant pleural mesothelioma. Am J Clin Oncol. 2015;38:47-50 pubmed publisher
Liu X, Kuriyan A, Amescua G. A painful red eye. JAMA Ophthalmol. 2015;133:95-6 pubmed publisher
Trendowski M, Wong V, Yu G, Fondy T. Enlargement and multinucleation of u937 leukemia and MCF7 breast carcinoma cells by antineoplastic agents to enhance sensitivity to low frequency ultrasound and to DNA-directed anticancer agents. Anticancer Res. 2015;35:65-76 pubmed
Panther D, Nino T, Macknet K, Macknet C. Eruptive keratoacanthomas as a complication of fractionated CO2 laser resurfacing and combination therapy with imiquimod and intralesional methotrexate. Dermatol Surg. 2015;41:172-5 pubmed publisher
Ieva R, Schrempp S, Opaliński L, Wollweber F, Höß P, Heißwolf A, et al. Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane. Mol Cell. 2014;56:641-52 pubmed publisher
Nowak D, Liem N, Mossner M, Klaumünzer M, Papa R, Nowak V, et al. Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance. Exp Hematol. 2015;43:32-43.e1-35 pubmed publisher
Sarker S, Kodali S, Weber F. A new meaning to butterflies in the stomach. Gastroenterology. 2015;148:e12-3 pubmed publisher
Keystone E, Taylor P, Drescher E, Schlichting D, Beattie S, Berclaz P, et al. Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate. Ann Rheum Dis. 2015;74:333-40 pubmed publisher
Polcari I, Moon A, Mathes E, Gilmore E, Paller A. Headaches as a presenting symptom of linear morphea en coup de sabre. Pediatrics. 2014;134:e1715-9 pubmed publisher
Tanimoto A, Ogawa Y, Oki C, Kimoto Y, Nozawa K, Amano W, et al. Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo. Inflamm Res. 2015;64:41-51 pubmed publisher
Emery P, Hammoudeh M, Fitzgerald O, Combe B, Martin Mola E, Buch M, et al. Sustained remission with etanercept tapering in early rheumatoid arthritis. N Engl J Med. 2014;371:1781-92 pubmed publisher
Kadia T, Kantarjian H, Thomas D, O Brien S, Estrov Z, Ravandi F, et al. Phase II study of methotrexate, vincristine, pegylated-asparaginase, and dexamethasone (MOpAD) in patients with relapsed/refractory acute lymphoblastic leukemia. Am J Hematol. 2015;90:120-4 pubmed publisher
Emery P, Burmester G, Bykerk V, Combe B, Furst D, Barré E, et al. Evaluating drug-free remission with abatacept in early rheumatoid arthritis: results from the phase 3b, multicentre, randomised, active-controlled AVERT study of 24?months, with a 12-month, double-blind treatment period. Ann Rheum Dis. 2015;74:19-26 pubmed publisher
Hoelzer D, Walewski J, Dohner H, Viardot A, Hiddemann W, Spiekermann K, et al. Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial. Blood. 2014;124:3870-9 pubmed publisher
Verschueren P, De Cock D, Corluy L, Joos R, Langenaken C, Taelman V, et al. Methotrexate in combination with other DMARDs is not superior to methotrexate alone for remission induction with moderate-to-high-dose glucocorticoid bridging in early rheumatoid arthritis after 16 weeks of treatment: the CareRA trial. Ann Rheum Dis. 2015;74:27-34 pubmed publisher
Hamilton B, Rybicki L, Dean R, Majhail N, Haddad H, Abounader D, et al. Cyclosporine in combination with mycophenolate mofetil versus methotrexate for graft versus host disease prevention in myeloablative HLA-identical sibling donor allogeneic hematopoietic cell transplantation. Am J Hematol. 2015;90:144-8 pubmed publisher
Levinsen M, Rosthøj S, Nygaard U, Heldrup J, Harila Saari A, Jonsson O, et al. Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity. Cancer Chemother Pharmacol. 2015;75:59-66 pubmed publisher
Wright K, Panetta J, Onar Thomas A, Reddick W, Patay Z, Qaddoumi I, et al. Delayed methotrexate excretion in infants and young children with primary central nervous system tumors and postoperative fluid collections. Cancer Chemother Pharmacol. 2015;75:27-35 pubmed publisher
Tuure L, Hämäläinen M, Moilanen T, Moilanen E. Aurothiomalate inhibits the expression of mPGES-1 in primary human chondrocytes. Scand J Rheumatol. 2015;44:74-9 pubmed publisher
Vrhovac I, Balen Eror D, Klessen D, Burger C, Breljak D, Kraus O, et al. Localizations of Na(+)-D-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart. Pflugers Arch. 2015;467:1881-98 pubmed publisher
Levin I, Cohen A, Almog B. Reply: To PMID 24657132. Am J Obstet Gynecol. 2015;212:122 pubmed publisher
Sholapurkar S. Methotrexate for ectopic pregnancy: success rates and avoidance of embryopathy. Am J Obstet Gynecol. 2015;212:121-2 pubmed publisher
Takeshita J, Wang S, Shin D, Callis Duffin K, Krueger G, Kalb R, et al. Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting. J Am Acad Dermatol. 2014;71:1167-75 pubmed publisher
Cohen A, Bibi G, Almog B, Tsafrir Z, Levin I. Second-dose methotrexate in ectopic pregnancies: the role of beta human chorionic gonadotropin. Fertil Steril. 2014;102:1646-9 pubmed publisher
Perinelli D, Bonacucina G, Pucciarelli S, Cespi M, Casettari L, Polzonetti V, et al. Could albumin affect the self-assembling properties of a block co-polymer system and drug release? An in-vitro study. Pharm Res. 2015;32:1094-104 pubmed publisher
Weinblatt M, Genovese M, Ho M, Hollis S, Rosiak Jedrychowicz K, Kavanaugh A, et al. Effects of fostamatinib, an oral spleen tyrosine kinase inhibitor, in rheumatoid arthritis patients with an inadequate response to methotrexate: results from a phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Arthritis Rheumatol. 2014;66:3255-64 pubmed publisher
Jin H, Cho H, Kim W, Mun J, Song M, Kim H, et al. Primary thyroid marginal zone B-cell lymphoma in a patient with psoriatic arthritis treated with etanercept. J Am Acad Dermatol. 2014;71:e152-3 pubmed publisher
Abdel M, Figgie M. Surgical management of the juvenile idiopathic arthritis patient with multiple joint involvement. Orthop Clin North Am. 2014;45:435-42 pubmed publisher
Georgiou K, Nadhanan R, Fan C, Xian C. Methotrexate-induced bone marrow adiposity is mitigated by folinic acid supplementation through the regulation of Wnt/β-catenin signalling. J Cell Physiol. 2015;230:648-56 pubmed publisher
Funk R, van Haandel L, Leeder J, Becker M. Folate depletion and increased glutamation in juvenile idiopathic arthritis patients treated with methotrexate. Arthritis Rheumatol. 2014;66:3476-85 pubmed publisher
Oberoi S, Trehan A, Marwaha R. Medication errors on oral chemotherapy in children with acute lymphoblastic leukemia in a developing country. Pediatr Blood Cancer. 2014;61:2218-22 pubmed publisher
Ylinen E, Jahnukainen K, Saarinen Pihkala U, Jahnukainen T. Assessment of renal function during high-dose methotrexate treatment in children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2014;61:2199-202 pubmed publisher
Huizinga T, Conaghan P, Martin Mola E, Schett G, Amital H, Xavier R, et al. Clinical and radiographic outcomes at 2 years and the effect of tocilizumab discontinuation following sustained remission in the second and third year of the ACT-RAY study. Ann Rheum Dis. 2015;74:35-43 pubmed publisher
Chande N, Wang Y, Macdonald J, McDonald J. Methotrexate for induction of remission in ulcerative colitis. Cochrane Database Syst Rev. 2014;:CD006618 pubmed publisher
Patel V, Wang Y, Macdonald J, McDonald J, Chande N. Methotrexate for maintenance of remission in Crohn's disease. Cochrane Database Syst Rev. 2014;:CD006884 pubmed publisher
Alexander S, Kraveka J, Weitzman S, Lowe E, Smith L, Lynch J, et al. Advanced stage anaplastic large cell lymphoma in children and adolescents: results of ANHL0131, a randomized phase III trial of APO versus a modified regimen with vinblastine: a report from the children's oncology group. Pediatr Blood Cancer. 2014;61:2236-42 pubmed publisher
Zhang H, He X, Wang C, Wang Y, Chen Y, Li J, et al. Impact of SLCO1B1 521T > C variant on leucovorin rescue and risk of relapse in childhood acute lymphoblastic leukemia treated with high-dose methotrexate. Pediatr Blood Cancer. 2014;61:2203-7 pubmed publisher
Byrne S, Lim M. N-methyl-D-aspartate receptor antibody encephalitis: how much treatment is enough?. Dev Med Child Neurol. 2015;57:14-5 pubmed publisher
McDonald J, Wang Y, Tsoulis D, Macdonald J, Feagan B. Methotrexate for induction of remission in refractory Crohn's disease. Cochrane Database Syst Rev. 2014;:CD003459 pubmed publisher
McLaren J, Barnhart K, Sammel M, Appleby D, Butts S. Success of the two-dose methotrexate protocol for treatment of ectopic pregnancy in women with a history of prior ectopic pregnancy. J Reprod Med. 2014;59:379-84 pubmed
Balar A, Milowsky M. Cytotoxic and DNA-targeted therapy in urothelial cancer: have we squeezed the lemon enough?. Cancer. 2015;121:179-87 pubmed publisher
Kim S, Park S, Kang E, Choi J, Lim D, Ko Y, et al. Induction treatment with SMILE and consolidation with autologous stem cell transplantation for newly diagnosed stage IV extranodal natural killer/T-cell lymphoma patients. Ann Hematol. 2015;94:71-8 pubmed publisher
Castellino S, Ullrich N, Whelen M, Lange B. Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors. J Natl Cancer Inst. 2014;106: pubmed publisher
Rytting M, Thomas D, O Brien S, Ravandi Kashani F, Jabbour E, Franklin A, et al. Augmented Berlin-Frankfurt-Münster therapy in adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL). Cancer. 2014;120:3660-8 pubmed publisher
Zgheib N, Akra Ismail M, Aridi C, Mahfouz R, Abboud M, Solh H, et al. Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia. Pharmacogenet Genomics. 2014;24:387-96 pubmed publisher
Humme D, Nast A, Erdmann R, Vandersee S, Beyer M. Systematic review of combination therapies for mycosis fungoides. Cancer Treat Rev. 2014;40:927-33 pubmed publisher
Symmonds M, Kuker W, Schulz U. Clinical reasoning: progressive visuospatial problems in a 71-year-old man. Neurology. 2014;83:e6-10 pubmed publisher
Necessary C, Roffwarg D, ELLIS D. Reticulated hyperpigmentation following chemotherapy for radiation-induced osteosarcoma. J Am Acad Dermatol. 2014;71:e23-4 pubmed publisher
Ram R, Herscovici C, Dahan D, Israeli M, Dreyer J, Peck A, et al. Tailoring the GVHD prophylaxis regimen according to transplantation associated toxicities-Substituting the 3rd dose of methotrexate to mycophenolate mofetil. Leuk Res. 2014;38:913-7 pubmed publisher
Schmiegelow K, Nielsen S, Frandsen T, Nersting J. Mercaptopurine/Methotrexate maintenance therapy of childhood acute lymphoblastic leukemia: clinical facts and fiction. J Pediatr Hematol Oncol. 2014;36:503-17 pubmed publisher
Holdhoff M, Ambady P, Abdelaziz A, Sarai G, Bonekamp D, Blakeley J, et al. High-dose methotrexate with or without rituximab in newly diagnosed primary CNS lymphoma. Neurology. 2014;83:235-9 pubmed publisher
Vora A, Goulden N, Mitchell C, Hancock J, Hough R, Rowntree C, et al. Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial. Lancet Oncol. 2014;15:809-18 pubmed publisher
Rathinam S, Babu M, Thundikandy R, Kanakath A, Nardone N, Esterberg E, et al. A randomized clinical trial comparing methotrexate and mycophenolate mofetil for noninfectious uveitis. Ophthalmology. 2014;121:1863-70 pubmed publisher
Burmester G, Kivitz A, Kupper H, Arulmani U, Florentinus S, Goss S, et al. Response to H Zeidler's comments on the CONCERTO study. Ann Rheum Dis. 2014;73:e51 pubmed publisher
Zou B, Han Z, Wang Z, Bian J, Xu J, Wang H, et al. Neoadjuvant therapy combined with a BMP regimen for treating penile cancer patients with lymph node metastasis: a retrospective study in China. J Cancer Res Clin Oncol. 2014;140:1733-8 pubmed publisher
Rashidi A, Maherus E. After the treated mole. Blood. 2014;123:2757 pubmed
Heath J, Burgett S, Gaca A, Jaffe R, Wechsler D. Successful treatment of pediatric histiocytic sarcoma using abbreviated high-risk leukemia chemotherapy. Pediatr Blood Cancer. 2014;61:1874-6 pubmed publisher
Jordan J, Plotkin S, Dietrich J. Magnetic resonance imaging observations in primary central nervous system lymphoma. JAMA Neurol. 2014;71:918-9 pubmed publisher
Sidbury R, Davis D, Cohen D, Cordoro K, Berger T, Bergman J, et al. Guidelines of care for the management of atopic dermatitis: section 3. Management and treatment with phototherapy and systemic agents. J Am Acad Dermatol. 2014;71:327-49 pubmed publisher
Hentrich M, Hoffmann C, Mosthaf F, Muller M, Siehl J, Wyen C, et al. Therapy of HIV-associated lymphoma-recommendations of the oncology working group of the German Study Group of Physicians in Private Practice Treating HIV-Infected Patients (DAGNÄ), in cooperation with the German AIDS Society (DAIG). Ann Hematol. 2014;93:913-21 pubmed publisher
Koens L, Senff N, Vermeer M, Willemze R, Jansen P. Methotrexate-associated B-cell lymphoproliferative disorders presenting in the skin: A clinicopathologic and immunophenotypical study of 10 cases. Am J Surg Pathol. 2014;38:999-1006 pubmed publisher
Schoffelen T, Kampschreur L, van Roeden S, Wever P, den Broeder A, Nabuurs Franssen M, et al. Coxiella burnetii infection (Q fever) in rheumatoid arthritis patients with and without anti-TNF? therapy. Ann Rheum Dis. 2014;73:1436-8 pubmed publisher
Sun N, Galvin J, Cooper K. Cutaneous Rosai-Dorfman disease successfully treated with low-dose methotrexate. JAMA Dermatol. 2014;150:787-8 pubmed publisher
de Jong P, Hazes J, Han H, Huisman M, Van Zeben D, van der Lubbe P, et al. Randomised comparison of initial triple DMARD therapy with methotrexate monotherapy in combination with low-dose glucocorticoid bridging therapy; 1-year data of the tREACH trial. Ann Rheum Dis. 2014;73:1331-9 pubmed publisher
Puttevils D, De Vusser P, Geusens P, Dens J. Increased cardiovascular risk in patients with rheumatoid arthritis: an overview. Acta Cardiol. 2014;69:111-8 pubmed
Zeidler H. The issue of bioavailability of oral low dose methotrexate: should we choose only 10 mg of MTX a week in conjunction with anti-TNF therapy?. Ann Rheum Dis. 2014;73:e50 pubmed publisher
Conway R, Low C, Coughlan R, O Donnell M, Carey J. Methotrexate and lung disease in rheumatoid arthritis: a meta-analysis of randomized controlled trials. Arthritis Rheumatol. 2014;66:803-12 pubmed publisher
Singer J, Fazekas J, Wang W, Weichselbaumer M, Matz M, Mader A, et al. Generation of a canine anti-EGFR (ErbB-1) antibody for passive immunotherapy in dog cancer patients. Mol Cancer Ther. 2014;13:1777-1790 pubmed publisher
Fushimi K, Tanabe N, Takami M. [A retrospective study of tegafur/uracil compared with cyclophosphamide, methotrexate, and fluorouracil as adjuvant chemotherapy in patients with node-negative, triple-negative breast cancer]. Gan To Kagaku Ryoho. 2014;41:449-53 pubmed
Bohelay G, Bouaziz J, Nunes H, Rybojad M, Bagot M, Petit A, et al. Striking leflunomide efficacy against refractory cutaneous sarcoidosis. J Am Acad Dermatol. 2014;70:e111-3 pubmed publisher
Schiff M, Jaffe J, Freundlich B. Head-to-head, randomised, crossover study of oral versus subcutaneous methotrexate in patients with rheumatoid arthritis: drug-exposure limitations of oral methotrexate at doses ≥15 mg may be overcome with subcutaneous administration. Ann Rheum Dis. 2014;73:1549-51 pubmed publisher
Soldini D, Gaspert A, Montani M, Reineke T, Rogler G, Odze R, et al. Apoptotic enteropathy caused by antimetabolites and TNF-α antagonists. J Clin Pathol. 2014;67:582-6 pubmed publisher
El Mesallamy H, Rashed W, Hamdy N, Hamdy N. High-dose methotrexate in Egyptian pediatric acute lymphoblastic leukemia: the impact of ABCG2 C421A genetic polymorphism on plasma levels, what is next?. J Cancer Res Clin Oncol. 2014;140:1359-65 pubmed publisher
Borradori L, Joly P. Toward a practical renaming of bullous pemphigoid and all its variants: cutaneous pemphigoid. JAMA Dermatol. 2014;150:459 pubmed publisher
de Rotte M, de Jong P, den Boer E, Pluijm S, Özcan B, Weel A, et al. Effect of methotrexate use and erythrocyte methotrexate polyglutamate on glycosylated hemoglobin in rheumatoid arthritis. Arthritis Rheumatol. 2014;66:2026-36 pubmed publisher
. In brief: otrexup--a single-use auto-injector formulation of methotrexate. Med Lett Drugs Ther. 2014;56:28 pubmed
Yamakawa T, Kurosawa M, Yonezumi M, Suzuki S, Suzuki H. [Methotrexate-related lymphomatoid granulomatosis successfully treated with discontinuation of methotrexate and radiotherapy to brain]. Rinsho Ketsueki. 2014;55:321-6 pubmed
Kenney L, Duffey Lind E, Ebb D, Sklar C, Grier H, Diller L. Impaired testicular function after an ifosfamide-containing regimen for pediatric osteosarcoma: a case series and review of the literature. J Pediatr Hematol Oncol. 2014;36:237-40 pubmed publisher
Ferreri A, Ciceri F, Brandes A, Montanari M, Balzarotti M, Spina M, et al. MATILDE chemotherapy regimen for primary CNS lymphoma: results at a median follow-up of 12 years. Neurology. 2014;82:1370-3 pubmed publisher
Yang Z, Zhao W, Liu W, Lv Q, Dong X. Efficacy evaluation of methotrexate in the treatment of ankylosing spondylitis using meta-analysis. Int J Clin Pharmacol Ther. 2014;52:346-51 pubmed publisher
Lossos C, Bayraktar S, Weinzierl E, Younes S, Hosein P, Tibshirani R, et al. LMO2 and BCL6 are associated with improved survival in primary central nervous system lymphoma. Br J Haematol. 2014;165:640-8 pubmed publisher
Kojima Y, Hagiwara S, Uehira T, Ajisawa A, Kitanaka A, Tanuma J, et al. Clinical outcomes of AIDS-related Burkitt lymphoma: a multi-institution retrospective survey in Japan. Jpn J Clin Oncol. 2014;44:318-23 pubmed publisher
Boots C, Gustofson R, Feinberg E. Reply of the authors. Fertil Steril. 2014;101:e24 pubmed publisher
Xiao C, Dahan M. The effect of methotrexate injection for treatment of an ectopic pregnancy on ovarian reserve. Fertil Steril. 2014;101:e23 pubmed publisher
Coutre S, Othus M, Powell B, Willman C, Stock W, Paietta E, et al. Arsenic trioxide during consolidation for patients with previously untreated low/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy. Br J Haematol. 2014;165:497-503 pubmed publisher
Conaghan P, Peterfy C, Olech E, Kaine J, Ridley D, Dicarlo J, et al. The effects of tocilizumab on osteitis, synovitis and erosion progression in rheumatoid arthritis: results from the ACT-RAY MRI substudy. Ann Rheum Dis. 2014;73:810-6 pubmed publisher
Ziółkowska H, Kisiel A, Leszczynska B, Bilska K, Jankowska K, Kuźma Mroczkowska E, et al. Continuous veno-venous hemodiafiltration in methotrexate intoxication. Med Wieku Rozwoj. 2013;17:347-54 pubmed
Plascencia Gomez A, Calderón Rocher C, Proy Trujillo H, Moreno Coutiño G. Neoadjuvant intralesional methotrexate before surgery in squamous cell carcinoma. Dermatol Surg. 2014;40:584-6 pubmed publisher
Perez Martín L, De Leon Luis J, Gámez Alderete F, Bravo C, Perez F, Aguaron A, et al. [Laparoscopic management of a spontaneous live monochorionic monoamniotic twin tubal ectopic pregnancy. A case report]. Ginecol Obstet Mex. 2013;81:612-5 pubmed
Dougados M, Kissel K, Conaghan P, Mola E, Schett G, Gerli R, et al. Clinical, radiographic and immunogenic effects after 1 year of tocilizumab-based treatment strategies in rheumatoid arthritis: the ACT-RAY study. Ann Rheum Dis. 2014;73:803-9 pubmed publisher
Sadasivam N, Johnson R, Owen R. Resolution of methotrexate-induced Epstein-Barr virus-associated mucocutaneous ulcer. Br J Haematol. 2014;165:584 pubmed publisher
Kume K, Amano K, Yamada S, Kanazawa T, Ohta H, Hatta K, et al. The effect of tocilizumab on bone mineral density in patients with methotrexate-resistant active rheumatoid arthritis. Rheumatology (Oxford). 2014;53:900-3 pubmed publisher
Yamanaka H, Ishiguro N, Takeuchi T, Miyasaka N, Mukai M, Matsubara T, et al. Recovery of clinical but not radiographic outcomes by the delayed addition of adalimumab to methotrexate-treated Japanese patients with early rheumatoid arthritis: 52-week results of the HOPEFUL-1 trial. Rheumatology (Oxford). 2014;53:904-13 pubmed publisher
Ram R, Yeshurun M, Vidal L, Shpilberg O, Gafter Gvili A. Mycophenolate mofetil vs. methotrexate for the prevention of graft-versus-host-disease--systematic review and meta-analysis. Leuk Res. 2014;38:352-60 pubmed publisher
Melachuri S, Gandrud L, Bostrom B. The association between fasting hypoglycemia and methylated mercaptopurine metabolites in children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2014;61:1003-6 pubmed publisher
Lee M, Lin R, Lai M. Increased risk of diabetes mellitus in relation to the severity of psoriasis, concomitant medication, and comorbidity: a nationwide population-based cohort study. J Am Acad Dermatol. 2014;70:691-698 pubmed publisher
Cao X, Li J, Zhang W, Duan M, Shen T, Zhou D. Patients with primary diffuse large B-cell lymphoma of female genital tract have high risk of central nervous system relapse. Ann Hematol. 2014;93:1001-5 pubmed publisher
Ota H, Koyama N, Nakamura A, Matsuda M, Yamamoto Y, Tomoda K, et al. [Case report; a case of methotrexate-associated lymphoproliferative disorders caused with multiple lung nodules]. Nihon Naika Gakkai Zasshi. 2013;102:2676-8 pubmed
Komagata Y. [Serious organ damage and intractable clinical conditions in rheumatic and connective tissue disease--progress in pathophysiology and treatment. Topics: II. Clinical conditions special attention needed to be paid to; 4. Macrophage activating syndrome. Nihon Naika Gakkai Zasshi. 2013;102:2639-44 pubmed
Kaneko J, Gozu K, Aoyagi H, Matsui T, Yoshida T, Hasegawa K, et al. [A case of iatrogenic immunodeficiency-associated lymphoproliferative disease in a patient treated with methotrexate for rheumatoid arthritis for 9 consecutive years, which Showed natural remission after discontinuation of MTX therapy]. Gan To Kagaku Ryoho. 2013;40:2454-6 pubmed
Fellows M, McDermott A, Clare K, Doherty A, Aardema M. The spectral karyotype of L5178Y TK⁺/⁻ mouse lymphoma cells clone 3.7.2C and factors affecting mutant frequency at the thymidine kinase (tk) locus in the microtitre mouse lymphoma assay. Environ Mol Mutagen. 2014;55:35-42 pubmed publisher
Perez Delboy A, Wright J. Surgical management of placenta accreta: to leave or remove the placenta?. BJOG. 2014;121:163-9; discussion 169-70 pubmed publisher
Fisher P. 50 years ago in the Journal of Pediatrics: central nervous system complications of children with acute leukemia: an evaluation of treatment methods. J Pediatr. 2014;164:33 pubmed publisher
Duffner P, ARMSTRONG F, Chen L, Helton K, Brecher M, Bell B, et al. Neurocognitive and neuroradiologic central nervous system late effects in children treated on Pediatric Oncology Group (POG) P9605 (standard risk) and P9201 (lesser risk) acute lymphoblastic leukemia protocols (ACCL0131): a methotrexate consequence? . J Pediatr Hematol Oncol. 2014;36:8-15 pubmed publisher
Nwanyanwu K, Lim J. Smudge in my vision. JAMA Ophthalmol. 2013;131:1637-8 pubmed publisher
Shea B. Folic acid or folinic acid for reducing side effects of methotrexate for people with rheumatoid arthritis. J Evid Based Med. 2013;6:202-3 pubmed publisher
Vu Hoang P, Ambroise J, Dang Chi V, Dekairelle A, Dupont S, Huynh N, et al. Comparison of long-term outcome between white and Vietnamese children treated for acute lymphoblastic leukemia according to the FRALLE 2000 protocol. J Pediatr Hematol Oncol. 2014;36:534-40 pubmed publisher
Hashkes P, Becker M, Cabral D, Laxer R, Paller A, Rabinovich C, et al. Methotrexate: new uses for an old drug. J Pediatr. 2014;164:231-6 pubmed publisher
Tamilselvi E, Haripriya D, Hemamalini M, Pushpa G, Swapna S. Association of disease severity with IL-1 levels in methotrexate-treated psoriasis patients. Scand J Immunol. 2013;78:545-53 pubmed publisher
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product information
Catalog Number :
A6770
Product Name :
Methotrexate hydrate
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA