This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Acetazolamide
catalog :
A6011
citations: 99
Reference
Lu B, Wang X, Ren Z, Jiang H, Liu B. Anti-glaucoma potential of hesperidin in experimental glaucoma induced rats. AMB Express. 2020;10:94 pubmed publisher
McLennan R, McKinney M, Teddy J, Morrison J, Kasemeier Kulesa J, Ridenour D, et al. Neural crest cells bulldoze through the microenvironment using Aquaporin 1 to stabilize filopodia. Development. 2020;147: pubmed publisher
Hwang S, Kang J, Kim M, Shin D, Hong J. Carbonic anhydrase 12 mutation modulates membrane stability and volume regulation of aquaporin 5. J Enzyme Inhib Med Chem. 2019;34:179-188 pubmed publisher
Scotton W, Botfield H, Westgate C, Mitchell J, Yiangou A, Uldall M, et al. Topiramate is more effective than acetazolamide at lowering intracranial pressure. Cephalalgia. 2019;39:209-218 pubmed publisher
Biancalana L, Batchelor L, Ciancaleoni G, Zacchini S, Pampaloni G, Dyson P, et al. Versatile coordination of acetazolamide to ruthenium(ii) p-cymene complexes and preliminary cytotoxicity studies. Dalton Trans. 2018;47:9367-9384 pubmed publisher
Pelkonen L, Tengvall Unadike U, Ruponen M, Kidron H, Del Amo E, Reinisalo M, et al. Melanin binding study of clinical drugs with cassette dosing and rapid equilibrium dialysis inserts. Eur J Pharm Sci. 2017;109:162-168 pubmed publisher
Ulmschneider B, Grillo Hill B, Benitez M, Azimova D, Barber D, Nystul T. Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation. J Cell Biol. 2016;215:345-355 pubmed
Qin S, Ren Y, Fu X, Shen J, Chen X, Wang Q, et al. Multiple ligand detection and affinity measurement by ultrafiltration and mass spectrometry analysis applied to fragment mixture screening. Anal Chim Acta. 2015;886:98-106 pubmed publisher
Yang M, Lu D, Chen J, Fu W. Inhibition of hyperactivity and impulsivity by carbonic anhydrase inhibitors in spontaneously hypertensive rats, an animal model of ADHD. Psychopharmacology (Berl). 2015;232:3763-72 pubmed publisher
Lee K, Prescott S. Chloride dysregulation and inhibitory receptor blockade yield equivalent disinhibition of spinal neurons yet are differentially reversed by carbonic anhydrase blockade. Pain. 2015;156:2431-7 pubmed publisher
Zito F, Koop D, Byrne M, Matranga V. Carbonic anhydrase inhibition blocks skeletogenesis and echinochrome production in Paracentrotus lividus and Heliocidaris tuberculata embryos and larvae. Dev Growth Differ. 2015;57:507-14 pubmed publisher
Andersen J, Henning W, Lindberg U, Ladefoged C, Højgaard L, Greisen G, et al. Positron emission tomography/magnetic resonance hybrid scanner imaging of cerebral blood flow using (15)O-water positron emission tomography and arterial spin labeling magnetic resonance imaging in newborn piglets. J Cereb Blood Flow Metab. 2015;35:1703-10 pubmed publisher
Sarada S, Titto M, Himadri P, Saumya S, Vijayalakshmi V. Curcumin prophylaxis mitigates the incidence of hypobaric hypoxia-induced altered ion channels expression and impaired tight junction proteins integrity in rat brain. J Neuroinflammation. 2015;12:113 pubmed publisher
Pham D, Grégoire N, Couet W, Gueutin C, Fattal E, Tsapis N. Pulmonary delivery of pyrazinamide-loaded large porous particles. Eur J Pharm Biopharm. 2015;94:241-50 pubmed publisher
Esbaugh A, Secor S, Grosell M. Characterization of carbonic anhydrase XIII in the erythrocytes of the Burmese python, Python molurus bivittatus. Comp Biochem Physiol B Biochem Mol Biol. 2015;187:71-7 pubmed publisher
Cramer S, Popa L, Carter R, Chen G, Ebner T. Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse. J Neurosci. 2015;35:5664-79 pubmed publisher
Czupryna J, Kachur A, Blankemeyer E, Popov A, Arroyo A, Karp J, et al. Cerenkov-specific contrast agents for detection of pH in vivo. J Nucl Med. 2015;56:483-8 pubmed publisher
Basting T, Burke P, Kanbar R, Viar K, Stornetta D, Stornetta R, et al. Hypoxia silences retrotrapezoid nucleus respiratory chemoreceptors via alkalosis. J Neurosci. 2015;35:527-43 pubmed publisher
Rajendran R, Sherry L, Lappin D, Nile C, Smith K, Williams C, et al. Extracellular DNA release confers heterogeneity in Candida albicans biofilm formation. BMC Microbiol. 2014;14:303 pubmed publisher
Nováková L, Rentsch M, Grand Guillaume Perrenoud A, Nicoli R, Saugy M, Veuthey J, et al. Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. II: Analysis of biological samples. Anal Chim Acta. 2015;853:647-59 pubmed publisher
Nováková L, Grand Guillaume Perrenoud A, Nicoli R, Saugy M, Veuthey J, Guillarme D. Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. I: Investigation of mobile phase and MS conditions. Anal Chim Acta. 2015;853:637-46 pubmed publisher
Ivanova L, Zandberga E, Siliņa K, Kalniņa Z, Ābols A, Endzeliņš E, et al. Prognostic relevance of carbonic anhydrase IX expression is distinct in various subtypes of breast cancer and its silencing suppresses self-renewal capacity of breast cancer cells. Cancer Chemother Pharmacol. 2015;75:235-46 pubmed publisher
De Rasmo D, Signorile A, Santeramo A, Larizza M, Lattanzio P, Capitanio G, et al. Intramitochondrial adenylyl cyclase controls the turnover of nuclear-encoded subunits and activity of mammalian complex I of the respiratory chain. Biochim Biophys Acta. 2015;1853:183-91 pubmed publisher
Eigenberger P, Faino A, Maltzahn J, Lisk C, Frank E, Frank A, et al. A retrospective study of acute mountain sickness on Mt. Kilimanjaro using trekking company data. Aviat Space Environ Med. 2014;85:1125-9 pubmed publisher
Caravita S, Faini A, Lombardi C, Valentini M, Gregorini F, Rossi J, et al. Sex and acetazolamide effects on chemoreflex and periodic breathing during sleep at altitude. Chest. 2015;147:120-131 pubmed publisher
Gustafsson J, Linden S, Alwan A, Scholte B, Hansson G, Sjovall H. Carbachol-induced colonic mucus formation requires transport via NKCC1, K⁺ channels and CFTR. Pflugers Arch. 2015;467:1403-1415 pubmed publisher
Miller S, Pollack J, Bradshaw J, Kumai Y, Perry S. Cardiac responses to hypercapnia in larval zebrafish (Danio rerio): the links between CO2 chemoreception, catecholamines and carbonic anhydrase. J Exp Biol. 2014;217:3569-78 pubmed publisher
Lockhart D, Schuettelkopf A, Blair D, van Aalten D. Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors. FEBS Lett. 2014;588:3282-90 pubmed publisher
Romand S, Schappler J, Veuthey J, Carrupt P, Martel S. cIEF for rapid pKa determination of small molecules: a proof of concept. Eur J Pharm Sci. 2014;63:14-21 pubmed publisher
Schumacher D, Müller Mottet S, Hasler E, Hildenbrand F, Keusch S, Speich R, et al. Effect of oxygen and acetazolamide on nocturnal cardiac conduction, repolarization, and arrhythmias in precapillary pulmonary hypertension and sleep-disturbed breathing. Chest. 2014;146:1226-1236 pubmed publisher
Di Rago M, Saar E, Rodda L, Turfus S, Kotsos A, Gerostamoulos D, et al. Fast targeted analysis of 132 acidic and neutral drugs and poisons in whole blood using LC-MS/MS. Forensic Sci Int. 2014;243:35-43 pubmed publisher
Wall M, McDermott M, KIEBURTZ K, Corbett J, Feldon S, Friedman D, et al. Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial. JAMA. 2014;311:1641-51 pubmed publisher
Horton J. Acetazolamide for pseudotumor cerebri: evidence from the NORDIC trial. JAMA. 2014;311:1618-9 pubmed publisher
Alperin N, Oliu C, Bagci A, Lee S, Kovanlikaya I, Adams D, et al. Low-dose acetazolamide reverses periventricular white matter hyperintensities in iNPH. Neurology. 2014;82:1347-51 pubmed publisher
Williams M. Comment: the trouble with "n" in normal-pressure hydrocephalus. Neurology. 2014;82:1350 pubmed publisher
Shahidullah M, Mandal A, Wei G, Levin L, Buck J, Delamere N. Nonpigmented ciliary epithelial cells respond to acetazolamide by a soluble adenylyl cyclase mechanism. Invest Ophthalmol Vis Sci. 2014;55:187-97 pubmed publisher
Harrison M, Anderson P, Miller A, O Malley K, Richert M, Johnson J, et al. Oral contraceptive use and acute mountain sickness in South Pole workers. Aviat Space Environ Med. 2013;84:1166-71 pubmed
Aure K, Dubourg O, Jardel C, Clarysse L, Sternberg D, Fournier E, et al. Episodic weakness due to mitochondrial DNA MT-ATP6/8 mutations. Neurology. 2013;81:1810-8 pubmed publisher
Scherrer U, Rexhaj E, Rimoldi S. Acute high-altitude illnesses. N Engl J Med. 2013;369:1665 pubmed publisher
Richalet J, Canoui Poitrine F, Canou Poitrine F, Larmignat P. Acute high-altitude illnesses. N Engl J Med. 2013;369:1664-5 pubmed publisher
Bartsch P, Swenson E. Acute high-altitude illnesses. N Engl J Med. 2013;369:1666-7 pubmed publisher
Wu F, Mi W, Cannon S. Beneficial effects of bumetanide in a CaV1.1-R528H mouse model of hypokalaemic periodic paralysis. Brain. 2013;136:3766-74 pubmed publisher
He M, Sheu M, Huang Z, Tsai C, Tsai R. Sudden bilateral vision loss and brain infarction following cosmetic hyaluronic acid injection. JAMA Ophthalmol. 2013;131:1234-5 pubmed publisher
Türkcü F, Yuksel H, Sahin A, Cinar Y, Cingu K, Ari S, et al. Effects of smoking on visual acuity of central serous chorioretinopathy patients. Cutan Ocul Toxicol. 2014;33:115-9 pubmed publisher
Singh J, Chhabra G, Pathak K. Development of acetazolamide-loaded, pH-triggered polymeric nanoparticulate in situ gel for sustained ocular delivery: in vitro. ex vivo evaluation and pharmacodynamic study. Drug Dev Ind Pharm. 2014;40:1223-32 pubmed publisher
Yamada S, Masahira N, Kawanishi Y, Fujimoto Y, Shimizu K. Preoperative acetazolamide SPECT is useful for predicting outcome of shunt operation in idiopathic normal pressure hydrocephalus patients. Clin Nucl Med. 2013;38:671-6 pubmed publisher
Bilginer S, Unluer E, Gul H, Mete E, Isik S, Vullo D, et al. Carbonic anhydrase inhibitors. Phenols incorporating 2- or 3-pyridyl-ethenylcarbonyl and tertiary amine moieties strongly inhibit Saccharomyces cerevisiae β-carbonic anhydrase. J Enzyme Inhib Med Chem. 2014;29:495-9 pubmed publisher
Golan S, Maslovitz S, Kupferminc M, Kesler A. Management and outcome of consecutive pregnancies complicated by idiopathic intracranial hypertension. Isr Med Assoc J. 2013;15:160-3 pubmed
Bartsch P, Swenson E. Clinical practice: Acute high-altitude illnesses. N Engl J Med. 2013;368:2294-302 pubmed publisher
Atmakuri M, Garritano F, Kanekar S, Ghossaini S. Radiology quiz case 1: suspected arachnoid cyst of the right cerebellopontineangle. JAMA Otolaryngol Head Neck Surg. 2013;139:519-21 pubmed publisher
Kotagal V. Acetazolamide-responsive ataxia. Semin Neurol. 2012;32:533-7 pubmed publisher
Brosh K, Strassman I. Unilateral papilledema in pseudotumor cerebri. Semin Ophthalmol. 2013;28:242-3 pubmed publisher
McKinley M. Adaptive appetites for salted and unsalted food in rats: differential effects of sodium depletion, DOCA, and dehydration. Am J Physiol Regul Integr Comp Physiol. 2013;304:R1149-60 pubmed publisher
Shiogai T, Koyama M, Yamamoto M, Hashimoto H, Yoshikawa K, Nakagawa M. Monitoring of brain tissue perfusion utilizing a transducer holder for transcranial color duplex sonography. Acta Neurochir Suppl. 2013;118:229-33 pubmed publisher
Igarashi H, Tsujita M, Suzuki Y, Kwee I, Nakada T. Inhibition of aquaporin-4 significantly increases regional cerebral blood flow. Neuroreport. 2013;24:324-8 pubmed publisher
Viuff A, Hansen J, Møller H. [Idiopathic intracranial hypertension is a rare cause of headache in children]. Ugeskr Laeger. 2013;175:661-2 pubmed
Barzegar Jalali M, Hanaee J, Omidi Y, Ghanbarzadeh S, Ziaee S, Bairami Atashgah R, et al. Preparation and evaluation of sustained release calcium alginate beads and matrix tablets of acetazolamide. Drug Res (Stuttg). 2013;63:60-4 pubmed publisher
Salvi P, Revera M, Faini A, Giuliano A, Gregorini F, Agostoni P, et al. Changes in subendocardial viability ratio with acute high-altitude exposure and protective role of acetazolamide. Hypertension. 2013;61:793-9 pubmed publisher
Huang Y, Zhou X, Wang H, Xu H, Chen J, Lv N. Aquaporin 5 promotes the proliferation and migration of human gastric carcinoma cells. Tumour Biol. 2013;34:1743-51 pubmed publisher
Yamamoto Y, Takahashi Y, Imai K, Mishima N, Yazawa R, Inoue K, et al. Risk factors for hyperammonemia in pediatric patients with epilepsy. Epilepsia. 2013;54:983-9 pubmed publisher
Betten D, Bridger D, Felton B. Profound alkalemia secondary to gastric outlet obstruction and acute renal insufficiency. Am J Emerg Med. 2013;31:444.e1-3 pubmed publisher
Johnston M. Brain SPECT imaging with acetazolamide challenge. J Nucl Med Technol. 2013;41:52-4, 10A pubmed publisher
Sood V, Rejali D, Stocker J, Pagliarini S, Ahluwalia H, Mehta P. A case report of orbital haemorrhage associated with endoscopic sinus surgery and reversible sight loss: a multidisciplinary approach to management. Orbit. 2013;32:73-5 pubmed publisher
Malagola R, Arrico L, Giannotti R, Pattavina L. Acetazolamide-induced cilio-choroidal effusion after cataract surgery: unusual posterior involvement. Drug Des Devel Ther. 2013;7:33-6 pubmed publisher
Edwards B, Connolly J, Campana L, Sands S, Trinder J, White D, et al. Acetazolamide attenuates the ventilatory response to arousal in patients with obstructive sleep apnea. Sleep. 2013;36:281-5 pubmed publisher
Victorio M, Rothner A. Diagnosis and treatment of idiopathic intracranial hypertension (IIH) in children and adolescents. Curr Neurol Neurosci Rep. 2013;13:336 pubmed publisher
Güzel Akdemir O, Akdemir A, Isik S, Vullo D, Supuran C. o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII. Bioorg Med Chem. 2013;21:1386-91 pubmed publisher
Wang J, Ke T, Zhang X, Chen Y, Liu M, Chen J, et al. Effects of acetazolamide on cognitive performance during high-altitude exposure. Neurotoxicol Teratol. 2013;35:28-33 pubmed publisher
Haustein M, Spoerl E, Boehm A. The effect of acetazolamide on different ocular vascular beds. Graefes Arch Clin Exp Ophthalmol. 2013;251:1389-98 pubmed publisher
Hour B, Shah A, Potharaju A, Lien Y. Quiz page January 2013: sudden deafness in a patient treated with long-term hemodialysis. Am J Kidney Dis. 2013;61:A29-31 pubmed publisher
Latshang T, Bloch K, Lynm C, Livingston E. JAMA patient page. Traveling to high altitude when you have sleep apnea. JAMA. 2012;308:2418 pubmed publisher
Latshang T, Nussbaumer Ochsner Y, Henn R, Ulrich S, Lo Cascio C, Ledergerber B, et al. Effect of acetazolamide and autoCPAP therapy on breathing disturbances among patients with obstructive sleep apnea syndrome who travel to altitude: a randomized controlled trial. JAMA. 2012;308:2390-8 pubmed publisher
Yang L, Hashemi N, Lee A. Intracranial complications of idiopathic intracranial hypertension. Can J Ophthalmol. 2012;47:e53-5 pubmed publisher
Yamamoto M, Matsuzaki T, Takahashi R, Adachi E, Maeda Y, Yamaguchi S, et al. The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs. Biol Open. 2012;1:458-66 pubmed publisher
Ali S, Seth R. X-linked juvenile retinoschisis in females and response to carbonic anhydrase inhibitors: case report and review of the literature. Semin Ophthalmol. 2013;28:50-4 pubmed publisher
Zanotto C, Abib R, Batassini C, Tortorelli L, Biasibetti R, Rodrigues L, et al. Non-specific inhibitors of aquaporin-4 stimulate S100B secretion in acute hippocampal slices of rats. Brain Res. 2013;1491:14-22 pubmed publisher
Yamaguchi T, Iwata Y, Miura S, Kawada K. Reinvestigation of drugs and chemicals as aquaporin-1 inhibitors using pressure-induced hemolysis in human erythrocytes. Biol Pharm Bull. 2012;35:2088-91 pubmed
Imray C. Acetazolamide for the prophylaxis of acute mountain sickness. BMJ. 2012;345:e7077 pubmed publisher
Low E, Avery A, Gupta V, Schedlbauer A, Grocott M. Identifying the lowest effective dose of acetazolamide for the prophylaxis of acute mountain sickness: systematic review and meta-analysis. BMJ. 2012;345:e6779 pubmed publisher
Ritchie N, Baggott A, Andrew Todd W. Acetazolamide for the prevention of acute mountain sickness--a systematic review and meta-analysis. J Travel Med. 2012;19:298-307 pubmed publisher
Kayser B, Dumont L, Lysakowski C, Combescure C, Haller G, Tramer M. Reappraisal of acetazolamide for the prevention of acute mountain sickness: a systematic review and meta-analysis. High Alt Med Biol. 2012;13:82-92 pubmed publisher
Farid K, Petras S, Ducasse V, Chokron S, Helft G, Blacher J, et al. Brain perfusion SPECT imaging and acetazolamide challenge in vascular cognitive impairment. Nucl Med Commun. 2012;33:571-80 pubmed publisher
Kassamali R, Sica D. Acetazolamide: a forgotten diuretic agent. Cardiol Rev. 2011;19:276-8 pubmed publisher
Her Y, Kil M, Park J, Kim C, Kim S. Stevens-Johnson syndrome induced by acetazolamide. J Dermatol. 2011;38:272-5 pubmed publisher
Kelly T, Hackett P. Acetazolamide and sulfonamide allergy: a not so simple story. High Alt Med Biol. 2010;11:319-23 pubmed publisher
Granero G, Longhi M. Promising complexes of acetazolamide for topical ocular administration. Expert Opin Drug Deliv. 2010;7:943-53 pubmed publisher
Vagal A, Leach J, Fernandez Ulloa M, Zuccarello M. The acetazolamide challenge: techniques and applications in the evaluation of chronic cerebral ischemia. AJNR Am J Neuroradiol. 2009;30:876-84 pubmed publisher
Bazzu G, Puggioni G, Dedola S, Calia G, Rocchitta G, Migheli R, et al. Real-time monitoring of brain tissue oxygen using a miniaturized biotelemetric device implanted in freely moving rats. Anal Chem. 2009;81:2235-41 pubmed publisher
Torring M, Holmgaard K, Hessellund A, Aalkjaer C, Bek T. The vasodilating effect of acetazolamide and dorzolamide involves mechanisms other than carbonic anhydrase inhibition. Invest Ophthalmol Vis Sci. 2009;50:345-51 pubmed publisher
Beck K. Flat beer vs. physiological improvement: effect of acetazolamide during hypoxic exercise. J Physiol. 2007;579:568-9 pubmed
López Menchero R, Albero M, Barrachina M, Alvarez L. [Anuric acute renal failure due to acetazolamide]. Nefrologia. 2006;26:755-6 pubmed
Leaf D, Goldfarb D. Mechanisms of action of acetazolamide in the prophylaxis and treatment of acute mountain sickness. J Appl Physiol (1985). 2007;102:1313-22 pubmed
Venance S, Jurkat Rott K, Lehmann Horn F, Tawil R. SCN4A-associated hypokalemic periodic paralysis merits a trial of acetazolamide. Neurology. 2004;63:1977 pubmed
Settakis G, Molnar C, Kerenyi L, Kollar J, Legemate D, Csiba L, et al. Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature. Eur J Neurol. 2003;10:609-20 pubmed
Kaur I, Smitha R, Aggarwal D, Kapil M. Acetazolamide: future perspective in topical glaucoma therapeutics. Int J Pharm. 2002;248:1-14 pubmed
Hoddevik G. [Acetazolamide--are there reasons for its revival in antiepileptic treatment?]. Tidsskr Nor Laegeforen. 2000;120:1042-5 pubmed
Hirata S, Koizumi M, Tanaka K. [Quantitation of acetazolamide]. Nihon Rinsho. 1999;57 Suppl:440-2 pubmed
Olson W. Acetazolamide relieves concurrent episodic movement disorders encountered in Southern states. South Med J. 1999;92:228-32 pubmed
Reiss W, Oles K. Acetazolamide in the treatment of seizures. Ann Pharmacother. 1996;30:514-9 pubmed
product information
Catalog Number :
A6011
Product Name :
Acetazolamide
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥99%, powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA