product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Anti-Water Channel Aquaporin 4 antibody produced in rabbit
catalog :
A5971
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 3c
Hoddevik E, Rao S, Zahl S, Boldt H, Ottersen O, Amiry Moghaddam M. Organisation of extracellular matrix proteins laminin and agrin in pericapillary basal laminae in mouse brain. Brain Struct Funct. 2020;225:805-816 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 2c
Kon T, Ueno T, Suzuki C, Nunomura J, Igarashi S, Sato T, et al. Aquaporin-4 antibody positive neuromyelitis optica spectrum disorder associated with esophageal cancer. J Neuroimmunol. 2017;309:38-40 pubmed publisher
  • other; mouse; 1:400; loading ...; fig 2a
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 3a
  • western blot; mouse; 1:5000; loading ...; fig 5c
Hoddevik E, Khan F, Rahmani S, Ottersen O, Boldt H, Amiry Moghaddam M. Factors determining the density of AQP4 water channel molecules at the brain-blood interface. Brain Struct Funct. 2017;222:1753-1766 pubmed publisher
Lohrberg M, Winkler A, Franz J, van der Meer F, Ruhwedel T, Sirmpilatze N, et al. Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination. Acta Neuropathol Commun. 2020;8:224 pubmed publisher
Xu G, Li Y, Ma C, Wang C, Sun Z, Shen Y, et al. Restraint Stress Induced Hyperpermeability and Damage of the Blood-Brain Barrier in the Amygdala of Adult Rats. Front Mol Neurosci. 2019;12:32 pubmed publisher
Mestre H, Hablitz L, Xavier A, Feng W, Zou W, Pu T, et al. Aquaporin-4-dependent glymphatic solute transport in the rodent brain. elife. 2018;7: pubmed publisher
Thornton M, Mehta M, Morad T, Ingraham K, Khankan R, Griffis K, et al. Evidence of axon connectivity across a spinal cord transection in rats treated with epidural stimulation and motor training combined with olfactory ensheathing cell transplantation. Exp Neurol. 2018;309:119-133 pubmed publisher
Dá Mesquita S, Louveau A, Vaccari A, Smirnov I, Cornelison R, Kingsmore K, et al. Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease. Nature. 2018;560:185-191 pubmed publisher
Dubey D, Hinson S, Jolliffe E, Zekeridou A, Flanagan E, Pittock S, et al. Autoimmune GFAP astrocytopathy: Prospective evaluation of 90 patients in 1?year. J Neuroimmunol. 2018;321:157-163 pubmed publisher
Baik K, Kim S, Shin H. Paraneoplastic Neuromyelitis Optica Associated with Lung Adenocarcinoma in a Young Woman. J Clin Neurol. 2018;14:246-247 pubmed publisher
Shahrokhi N, Khaksari M, Asadikaram G, Soltani Z, Shahrokhi N. Role of melatonin receptors in the effect of estrogen on brain edema, intracranial pressure and expression of aquaporin 4 after traumatic brain injury. Iran J Basic Med Sci. 2018;21:301-308 pubmed publisher
Liu J, REEVES C, Jacques T, McEvoy A, Miserocchi A, Thompson P, et al. Nestin-expressing cell types in the temporal lobe and hippocampus: Morphology, differentiation, and proliferative capacity. Glia. 2018;66:62-77 pubmed publisher
Todd K, Brighton T, Norton E, Schick S, Elkins W, Pletnikova O, et al. Ventricular and Periventricular Anomalies in the Aging and Cognitively Impaired Brain. Front Aging Neurosci. 2017;9:445 pubmed publisher
Vindedal G, Thoren A, Jensen V, Klungland A, Zhang Y, Holtzman M, et al. Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation. Mol Cell Neurosci. 2016;77:47-52 pubmed publisher
Tuller F, Holzer H, Schanda K, Aboulenein Djamshidian F, Hoftberger R, Khalil M, et al. Characterization of the binding pattern of human aquaporin-4 autoantibodies in patients with neuromyelitis optica spectrum disorders. J Neuroinflammation. 2016;13:176 pubmed publisher
Kimbrough I, Robel S, Roberson E, Sontheimer H. Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer's disease. Brain. 2015;138:3716-33 pubmed publisher
Geis C, Ritter C, Ruschil C, Weishaupt A, Grünewald B, Stoll G, et al. The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model. Exp Neurol. 2015;265:8-21 pubmed publisher
product information
Product No. :
A5971
Product Name :
Anti-Water Channel Aquaporin 4 antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for flow cytometry (indirect); western blot; immunohistochemistry; immunocytochemistry
Species Reactivity :
rat, human, mouse
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA