This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Amifostine trihydrate
catalog :
A5922
citations: 32
Reference
Qu X, Li Q, Zhang X, Wang Z, Wang S, Zhou Z. Amentoflavone protects the hematopoietic system of mice against γ-irradiation. Arch Pharm Res. 2019;42:1021-1029 pubmed publisher
Varghese J, Schmale I, Mickelsen D, Hansen M, Newlands S, Benoit D, et al. Localized Delivery of Amifostine Enhances Salivary Gland Radioprotection. J Dent Res. 2018;97:1252-1259 pubmed publisher
Sarhaddi D, Tchanque Fossuo C, Poushanchi B, Donneys A, Deshpande S, Weiss D, et al. Amifostine protects vascularity and improves union in a model of irradiated mandibular fracture healing. Plast Reconstr Surg. 2013;132:1542-9 pubmed publisher
Chen C, Tian L, Zhang M, Sun Q, Zhang X, Li X, et al. Protective effect of amifostine on high-dose methotrexate-induced small intestinal mucositis in mice. Dig Dis Sci. 2013;58:3134-43 pubmed publisher
A G, Ren L, Zhou Z, Lu D, Wang S. Design and evaluation of biodegradable enteric microcapsules of amifostine for oral delivery. Int J Pharm. 2013;453:441-7 pubmed publisher
Ozdemir C, Burgazli K, Beken Ozdemir E, Akdere H, Mericliler M, Ozcelik M. The effect of Amifostine (Ethyol) on intestinal anastomosis in rats with radiation enteritis. Eur Rev Med Pharmacol Sci. 2013;17:1351-9 pubmed
Dragojevic Simic V, Dobric S, Jacevic V, Bokonjic D, Milosavljević I, Kovacević A, et al. Efficacy of amifostine in protection against doxorubicin-induced acute cardiotoxic effects in rats. Vojnosanit Pregl. 2013;70:38-45 pubmed
Pillai T, Uma Devi P. Mushroom beta glucan: potential candidate for post irradiation protection. Mutat Res. 2013;751:109-15 pubmed publisher
Epperly M, Bahary N, Quader M, Dewald V, Greenberger J. The zebrafish--Danio rerio--is a useful model for measuring the effects of small-molecule mitigators of late effects of ionizing irradiation. In Vivo. 2012;26:889-97 pubmed
Gomez H, Samanez C, Campana F, Neciosup S, Vera L, Casanova L, et al. Addition of amifostine to the CHOP regimen in elderly patients with aggressive non-Hodgkin lymphoma: a phase II trial showing reduction in toxicity without altering long-term survival. Hematol Oncol Stem Cell Ther. 2012;5:152-7 pubmed publisher
Duval M, Daniel S. Meta-analysis of the efficacy of amifostine in the prevention of cisplatin ototoxicity. J Otolaryngol Head Neck Surg. 2012;41:309-15 pubmed
Koukourakis M, Papadopoulou A, Abatzoglou I, Panteliadou M, Sismanidou K, Touloupidis S. Postoperative pelvic hypofractionated accelerated radiotherapy with cytoprotection (HypoARC) for high-risk or recurrent prostate cancer. Anticancer Res. 2012;32:4561-8 pubmed
Nicolatou Galitis O, Sarri T, Bowen J, Di Palma M, Kouloulias V, Niscola P, et al. Systematic review of amifostine for the management of oral mucositis in cancer patients. Support Care Cancer. 2013;21:357-64 pubmed publisher
Koukourakis M, Panteliadou M, Abatzoglou I, Sismanidou K, Sivridis E, Giatromanolaki A. Postmastectomy hypofractionated and accelerated radiation therapy with (and without) subcutaneous amifostine cytoprotection. Int J Radiat Oncol Biol Phys. 2013;85:e7-13 pubmed publisher
Wang S, Zhang Y, Zhang S, Ma S. [Effect of amifostine on locally advanced non-small cell lung cancer patients treated with radiotherapy: a meta-analysis of randomized controlled trials]. Zhongguo Fei Ai Za Zhi. 2012;15:539-44 pubmed
Tchanque Fossuo C, Gong B, Poushanchi B, Donneys A, Sarhaddi D, Gallagher K, et al. Raman spectroscopy demonstrates Amifostine induced preservation of bone mineralization patterns in the irradiated murine mandible. Bone. 2013;52:712-717 pubmed publisher
Tchanque Fossuo C, Donneys A, Razdolsky E, Monson L, Farberg A, Deshpande S, et al. Quantitative histologic evidence of amifostine-induced cytoprotection in an irradiated murine model of mandibular distraction osteogenesis. Plast Reconstr Surg. 2012;130:1199-207 pubmed publisher
Caloglu M, Caloglu V, Yalta T, Yalcin O, Uzal C. The histopathological comparison of L-carnitine with amifostine for protective efficacy on radiation-induced acute small intestinal toxicity. J Cancer Res Ther. 2012;8:260-5 pubmed publisher
Russo I, Viretto M, Barale C, Mattiello L, Doronzo G, Pagliarino A, et al. High glucose inhibits the aspirin-induced activation of the nitric oxide/cGMP/cGMP-dependent protein kinase pathway and does not affect the aspirin-induced inhibition of thromboxane synthesis in human platelets. Diabetes. 2012;61:2913-21 pubmed publisher
Jagosova J, Pitrova L, Slovackova J, Ravcukova B, Smarda J, Smardova J. Transactivation and reactivation capabilities of temperature-dependent p53 mutants in yeast and human cells. Int J Oncol. 2012;41:1157-63 pubmed publisher
Vendramini V, Robaire B, Miraglia S. Amifostine-doxorubicin association causes long-term prepubertal spermatogonia DNA damage and early developmental arrest. Hum Reprod. 2012;27:2457-66 pubmed publisher
van As J, van den Berg H, van Dalen E. Medical interventions for the prevention of platinum-induced hearing loss in children with cancer. Cochrane Database Syst Rev. 2012;:CD009219 pubmed publisher
Zhengdong K, Zhaofan X, Mengwei T. Low-dose antioxidant is sufficient to regulate pulmonary redox equilibration. Crit Care Med. 2012;40:1693-4 pubmed publisher
Melis M, Valkema R, Krenning E, de Jong M. Reduction of renal uptake of radiolabeled octreotate by amifostine coadministration. J Nucl Med. 2012;53:749-53 pubmed publisher
Tchanque Fossuo C, Donneys A, Deshpande S, Nelson N, Boguslawski M, Gallagher K, et al. Amifostine remediates the degenerative effects of radiation on the mineralization capacity of the murine mandible. Plast Reconstr Surg. 2012;129:646e-55e pubmed publisher
Oʼdonovan D, La Scala G, Leong I, Mendes M, Rogers M, Pritzker K, et al. Radiation-induced craniofacial bone growth inhibition: acute and long-term effects on bone histopathology with and without cytoprotection. Plast Reconstr Surg. 2012;129:636e-45e pubmed publisher
Feng M, Smith D, Normolle D, Knol J, Pan C, Ben Josef E, et al. A phase I clinical and pharmacology study using amifostine as a radioprotector in dose-escalated whole liver radiation therapy. Int J Radiat Oncol Biol Phys. 2012;83:1441-7 pubmed publisher
Cakmak G, Miller L, Zorlu F, Severcan F. Amifostine, a radioprotectant agent, protects rat brain tissue lipids against ionizing radiation induced damage: an FTIR microspectroscopic imaging study. Arch Biochem Biophys. 2012;520:67-73 pubmed publisher
Joseph J, Panicker S, Janardhanan K. Protective effect of polysaccharide-protein complex from a polypore mushroom, Phellinus rimosus against radiation-induced oxidative stress. Redox Rep. 2012;17:22-7 pubmed publisher
SOREF C, Hacker T, Fahl W. A new orally active, aminothiol radioprotector-free of nausea and hypotension side effects at its highest radioprotective doses. Int J Radiat Oncol Biol Phys. 2012;82:e701-7 pubmed publisher
Spencer C, Goa K. Amifostine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential as a radioprotector and cytotoxic chemoprotector. Drugs. 1995;50:1001-31 pubmed
Capizzi R, Scheffler B, Schein P. Amifostine-mediated protection of normal bone marrow from cytotoxic chemotherapy. Cancer. 1993;72:3495-501 pubmed
product information
Catalog Number :
A5922
Product Name :
Amifostine trihydrate
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥97% (TLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA