This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Adenine 9-β-D-arabinofuranoside
catalog :
A5762
citations: 87
Reference
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Chantepie S, Gac A, Reman O. Feasibility of the fludarabine busulfan 3 days and ATG 2 days reduced toxicity conditioning in 51 allogeneic hematopoietic stem cell transplantation: a single-center experience. Leuk Res. 2014;38:569-74 pubmed publisher
Legert K, Remberger M, Ringden O, Heimdahl A, Dahllöf G. Reduced intensity conditioning and oral care measures prevent oral mucositis and reduces days of hospitalization in allogeneic stem cell transplantation recipients. Support Care Cancer. 2014;22:2133-40 pubmed publisher
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Hill B, Caimi P, Kindwall Keller T, Habecker B, Kalaycio M. Bendamustine plus alemtuzumab is safe and feasible treatment for fludarabine refractory chronic lymphocytic leukaemia (CLL). Br J Haematol. 2014;164:297-9 pubmed publisher
Johnson G, Lin K, Cox T, Oates M, Sibson D, Eccles R, et al. CYP2B6*6 is an independent determinant of inferior response to fludarabine plus cyclophosphamide in chronic lymphocytic leukemia. Blood. 2013;122:4253-8 pubmed publisher
Abrisqueta P, Villamor N, Terol M, Gonzalez Barca E, Gonzalez M, Ferra C, et al. Rituximab maintenance after first-line therapy with rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) for chronic lymphocytic leukemia. Blood. 2013;122:3951-9 pubmed publisher
Gao L, Gao L, Gong Y, Zhang C, Chen X, Zhang X. Reduced-intensity conditioning therapy with fludarabine, idarubicin, busulfan and cytarabine for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia and myelodysplastic syndrome. Leuk Res. 2013;37:1482-7 pubmed publisher
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Strati P, Wierda W, Burger J, Ferrajoli A, Tam C, Lerner S, et al. Myelosuppression after frontline fludarabine, cyclophosphamide, and rituximab in patients with chronic lymphocytic leukemia: analysis of persistent and new-onset cytopenia. Cancer. 2013;119:3805-11 pubmed publisher
Prins R, Burke R, Tyner J, Druker B, Loriaux M, Spurgeon S. CX-4945, a selective inhibitor of casein kinase-2 (CK2), exhibits anti-tumor activity in hematologic malignancies including enhanced activity in chronic lymphocytic leukemia when combined with fludarabine and inhibitors of the B-cell receptor pathway. Leukemia. 2013;27:2094-6 pubmed publisher
Zinzani P, Pellegrini C, Broccoli A, Casadei B, Argnani L, Pileri S. Fludarabine-mitoxantrone-rituximab regimen in untreated intermediate/high-risk follicular non-Hodgkin's lymphoma: experience on 142 patients. Am J Hematol. 2013;88:E273-6 pubmed publisher
Pantin J, Tian X, Shah A, Kurlander R, Ramos C, Cook L, et al. Rapid donor T-cell engraftment increases the risk of chronic graft-versus-host disease following salvage allogeneic peripheral blood hematopoietic cell transplantation for bone marrow failure syndromes. Am J Hematol. 2013;88:874-82 pubmed publisher
Fink A, Bottcher S, Ritgen M, Fischer K, Pflug N, Eichhorst B, et al. Prediction of poor outcome in CLL patients following first-line treatment with fludarabine, cyclophosphamide and rituximab. Leukemia. 2013;27:1949-52 pubmed publisher
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Clavio M, Cruciani F, Minetto P, Guolo F, Ballerini F, Marani C, et al. De novo AML patients with favourable-intermediate karyotype may benefit from the addition of low-dose gemtuzumab ozogamicin (GO) to fludarabine, Ara-C and idarubicin (FLAI): a contribution to the reopened "GO question". Ann Hematol. 2013;92:1309-18 pubmed publisher
Koteda S, Nomura K, Hashiguchi M, Kawaguchi K, Oku E, Osaki K, et al. [Fatal zygomycosis caused by Mucor indicus after haplo-identical stem cell transplantation]. Rinsho Ketsueki. 2013;54:311-5 pubmed
Pan H, Ma Y, Wang D, Wang J, Jiang H, Pan S, et al. Effect of IFN-α on KC and LIX expression: role of STAT1 and its effect on neutrophil recruitment to the spleen after lipopolysaccharide stimulation. Mol Immunol. 2013;56:12-22 pubmed publisher
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Miano M, Poggi V, Banov L, Fioredda F, Micalizzi C, Svahn J, et al. Sirolimus as maintenance treatment in an infant with life-threatening multiresistant pure red cell anemia/autoimmune hemolytic anemia. J Pediatr Hematol Oncol. 2014;36:e145-8 pubmed publisher
Toporkiewicz M, Grzybek M, Meissner J, Michalczyk I, Dubielecka P, Korycka J, et al. Release of an ~55kDa fragment containing the actin-binding domain of β-spectrin by caspase-8 during FND-induced apoptosis depends on the presence of protein 4.1. Arch Biochem Biophys. 2013;535:205-13 pubmed publisher
Federico M, Luminari S, Dondi A, Tucci A, Vitolo U, Rigacci L, et al. R-CVP versus R-CHOP versus R-FM for the initial treatment of patients with advanced-stage follicular lymphoma: results of the FOLL05 trial conducted by the Fondazione Italiana Linfomi. J Clin Oncol. 2013;31:1506-13 pubmed publisher
Xiang L, Li M, Liu Y, Cen J, Chen Z, Zhen X, et al. The clinical characteristics and prognostic significance of MN1 gene and MN1-associated microRNA expression in adult patients with de novo acute myeloid leukemia. Ann Hematol. 2013;92:1063-9 pubmed publisher
Hopfinger G, Busch R, Pflug N, Weit N, Westermann A, Fink A, et al. Sequential chemoimmunotherapy of fludarabine, mitoxantrone, and cyclophosphamide induction followed by alemtuzumab consolidation is effective in T-cell prolymphocytic leukemia. Cancer. 2013;119:2258-67 pubmed publisher
Dörffel W, Rühl U, Lüders H, Claviez A, Albrecht M, Bökkerink J, et al. Treatment of children and adolescents with Hodgkin lymphoma without radiotherapy for patients in complete remission after chemotherapy: final results of the multinational trial GPOH-HD95. J Clin Oncol. 2013;31:1562-8 pubmed publisher
Panovská A, Smolej L, Lysak D, Brychtova Y, Simkovic M, Motyčková M, et al. The outcome of chronic lymphocytic leukemia patients who relapsed after fludarabine, cyclophosphamide, and rituximab. Eur J Haematol. 2013;90:479-85 pubmed publisher
Fahrmann J, Hardman W. Omega 3 fatty acids increase the chemo-sensitivity of B-CLL-derived cell lines EHEB and MEC-2 and of B-PLL-derived cell line JVM-2 to anti-cancer drugs doxorubicin, vincristine and fludarabine. Lipids Health Dis. 2013;12:36 pubmed publisher
Bogusz J, Majchrzak A, Mędra A, Cebula Obrzut B, Robak T, Smolewski P. Mechanisms of action of the anti-VEGF monoclonal antibody bevacizumab on chronic lymphocytic leukemia cells. Postepy Hig Med Dosw (Online). 2013;67:107-18 pubmed
Anderson E, Smith M, Martin A, Ruddock M, Lamont J, Alloush H, et al. A novel bioluminescent bacterial biosensor for measurement of Ara-CTP and cytarabine potentiation by fludarabine in seven leukaemic cell lines. Leuk Res. 2013;37:690-6 pubmed publisher
Schmutz J, Trechot P. [Subcutaneous panniculitis-like T-cell lymphoma following treatment with rituximab and cyclophosphamide]. Ann Dermatol Venereol. 2013;140:246-7 pubmed publisher
Kanda Y, Oshima K, Kako S, Fukuda T, Uchida N, Miyamura K, et al. In vivo T-cell depletion with alemtuzumab in allogeneic hematopoietic stem cell transplantation: Combined results of two studies on aplastic anemia and HLA-mismatched haploidentical transplantation. Am J Hematol. 2013;88:294-300 pubmed publisher
Hussein A, Al Zaben A, Ghatasheh L, Natsheh A, Hammada T, Abdel Rahman F, et al. Risk adopted allogeneic hematopoietic stem cell transplantation using a reduced intensity regimen for children with thalassemia major. Pediatr Blood Cancer. 2013;60:1345-9 pubmed publisher
Radhakrishnan K, Bhatia M, Geyer M, del Toro G, Jin Z, Baker C, et al. Busulfan, fludarabine, and alemtuzumab conditioning and unrelated cord blood transplantation in children with sickle cell disease. Biol Blood Marrow Transplant. 2013;19:676-7 pubmed publisher
Liu H, Zhai X, Song Z, Sun J, Xiao Y, Nie D, et al. Busulfan plus fludarabine as a myeloablative conditioning regimen compared with busulfan plus cyclophosphamide for acute myeloid leukemia in first complete remission undergoing allogeneic hematopoietic stem cell transplantation: a prospective and mul. J Hematol Oncol. 2013;6:15 pubmed publisher
Raphael M, Rottier B, Boelens J. Fludarabine in paediatric steroid-refractory inflammatory lung injury after stem cell transplantation. Eur Respir J. 2013;41:479-83 pubmed publisher
Niederle N, Megdenberg D, Balleisen L, Heit W, Knauf W, Weis J, et al. Bendamustine compared to fludarabine as second-line treatment in chronic lymphocytic leukemia. Ann Hematol. 2013;92:653-60 pubmed publisher
Kaspers G, Zimmermann M, Reinhardt D, Gibson B, Tamminga R, Aleinikova O, et al. Improved outcome in pediatric relapsed acute myeloid leukemia: results of a randomized trial on liposomal daunorubicin by the International BFM Study Group. J Clin Oncol. 2013;31:599-607 pubmed publisher
Barba P, Valcarcel D, Perez Simon J, Fernandez Aviles F, Piñana J, Martino R, et al. Impact of hyperferritinemia on the outcome of reduced-intensity conditioning allogeneic hematopoietic cell transplantation for lymphoid malignancies. Biol Blood Marrow Transplant. 2013;19:597-601 pubmed publisher
Le Bourgeois A, Lestang E, Guillaume T, Delaunay J, Ayari S, Blin N, et al. Prognostic impact of immune status and hematopoietic recovery before and after fludarabine, IV busulfan, and antithymocyte globulins (FB2 regimen) reduced-intensity conditioning regimen (RIC) allogeneic stem cell transplantation (allo-SCT). Eur J Haematol. 2013;90:177-86 pubmed publisher
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Novitzky N, Thomas V, du Toit C. Conditioning with purine analogs leads to good engraftment rates of immunodepleted grafts for aplastic anemia. Biol Blood Marrow Transplant. 2013;19:584-8 pubmed publisher
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Diker Cohen T, Uziel O, Szyper Kravitz M, Shapira H, Natur A, Lahav M. The effect of chemotherapy on telomere dynamics: clinical results and possible mechanisms. Leuk Lymphoma. 2013;54:2023-9 pubmed publisher
Leblond V, Johnson S, Chevret S, Copplestone A, Rule S, Tournilhac O, et al. Results of a randomized trial of chlorambucil versus fludarabine for patients with untreated Waldenström macroglobulinemia, marginal zone lymphoma, or lymphoplasmacytic lymphoma. J Clin Oncol. 2013;31:301-7 pubmed publisher
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W. Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 2011;7:e1002310 pubmed publisher
Peterson L, Kim J, Kijek P, Mitchell S, Hilfinger J, Breitenbach J, et al. Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir. Bioorg Med Chem Lett. 2011;21:4045-9 pubmed publisher
Ekins S, Williams A, Xu J. A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug Metab Dispos. 2010;38:2302-8 pubmed publisher
Greene N, Fisk L, Naven R, Note R, Patel M, Pelletier D. Developing structure-activity relationships for the prediction of hepatotoxicity. Chem Res Toxicol. 2010;23:1215-22 pubmed publisher
Fourches D, Barnes J, Day N, Bradley P, Reed J, Tropsha A. Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chem Res Toxicol. 2010;23:171-83 pubmed publisher
Diez Torrubia A, García Aparicio C, Cabrera S, De Meester I, Balzarini J, Camarasa M, et al. Application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to different amine-containing drugs. J Med Chem. 2010;53:559-72 pubmed publisher
Krug P, Schinazi R, Hilliard J. Inhibition of B virus (Macacine herpesvirus 1) by conventional and experimental antiviral compounds. Antimicrob Agents Chemother. 2010;54:452-9 pubmed publisher
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Yu P, Hong C, Sachidanandan C, Babitt J, Deng D, Hoyng S, et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 2008;4:33-41 pubmed
Terasaka T, Tsuji K, Kato T, Nakanishi I, Kinoshita T, Kato Y, et al. Rational design of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors: predicting enzyme conformational change and metabolism. J Med Chem. 2005;48:4750-3 pubmed
product information
Catalog Number :
A5762
Product Name :
Adenine 9-β-D-arabinofuranoside
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥99%
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA