product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-β-Amyloid antibody produced in mouse
catalog :
A5213
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BAM-10
reactivity :
human, mouse
application :
immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 4a
Yang Y, He Z, Xing Z, Zuo Z, Yuan L, Wu Y, et al. Influenza vaccination in early Alzheimer's disease rescues amyloidosis and ameliorates cognitive deficits in APP/PS1 mice by inhibiting regulatory T cells. J Neuroinflammation. 2020;17:65 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2d
Stachowicz A, Olszanecki R, Suski M, Głombik K, Basta Kaim A, Adamek D, et al. Proteomic Analysis of Mitochondria-Enriched Fraction Isolated from the Frontal Cortex and Hippocampus of Apolipoprotein E Knockout Mice Treated with Alda-1, an Activator of Mitochondrial Aldehyde Dehydrogenase (ALDH2). Int J Mol Sci. 2017;18: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4
Park T, Ryu Y, Park H, Kim J, Go J, Noh J, et al. Humulus japonicus inhibits the progression of Alzheimer's disease in a APP/PS1 transgenic mouse model. Int J Mol Med. 2017;39:21-30 pubmed publisher
Gary C, Lam S, Herard A, Koch J, Petit F, Gipchtein P, et al. Encephalopathy induced by Alzheimer brain inoculation in a non-human primate. Acta Neuropathol Commun. 2019;7:126 pubmed publisher
Ceyzériat K, Ben Haim L, Denizot A, Pommier D, Matos M, Guillemaud O, et al. Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease. Acta Neuropathol Commun. 2018;6:104 pubmed publisher
Chou C, Lee Y, Liao C, Huang Y, Fan C. Enhanced expressions of neurodegeneration-associated factors, UPS impairment, and excess A? accumulation in the hippocampus of mice with persistent cerebral toxocariasis. Parasit Vectors. 2017;10:620 pubmed publisher
Zuo Z, Qi F, Yang J, Wang X, Wu Y, Wen Y, et al. Immunization with Bacillus Calmette-Guérin (BCG) alleviates neuroinflammation and cognitive deficits in APP/PS1 mice via the recruitment of inflammation-resolving monocytes to the brain. Neurobiol Dis. 2017;101:27-39 pubmed publisher
Tian T, Bai D, Li W, Huang G, Liu H. Effects of Folic Acid on Secretases Involved in A? Deposition in APP/PS1 Mice. Nutrients. 2016;8: pubmed publisher
Puig K, Kulas J, Franklin W, Rakoczy S, Taglialatela G, Brown Borg H, et al. The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice. Neurobiol Aging. 2016;40:22-40 pubmed publisher
Dong X, Gao W, Kong W, Xie H, Peng Y, Shao T, et al. Neuroprotective effect of the active components of three Chinese herbs on brain iron load in a mouse model of Alzheimer's disease. Exp Ther Med. 2015;9:1319-1327 pubmed
Kim T, Han H, Kim H, Lee J, Choi D, Park W, et al. Expression of the plant viral protease NIa in the brain of a mouse model of Alzheimer's disease mitigates A? pathology and improves cognitive function. Exp Mol Med. 2012;44:740-8 pubmed publisher
Kim T, Lee J, Park S, Lee K, Seo J, Im J, et al. Analysis of differential plaque depositions in the brains of Tg2576 and Tg-APPswe/PS1dE9 transgenic mouse models of Alzheimer disease. Exp Mol Med. 2012;44:492-502 pubmed publisher
Jeon S, Bose S, Hur J, Jun K, Kim Y, Cho K, et al. A modified formulation of Chinese traditional medicine improves memory impairment and reduces A? level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease. J Ethnopharmacol. 2011;137:783-9 pubmed publisher
Seo J, Lee K, Kim T, Baek I, Im J, Han P. Behavioral stress causes mitochondrial dysfunction via ABAD up-regulation and aggravates plaque pathology in the brain of a mouse model of Alzheimer disease. Free Radic Biol Med. 2011;50:1526-35 pubmed publisher
Wang C, Zheng W, Wang T, Xie J, Wang S, Zhao B, et al. Huperzine A activates Wnt/?-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse model. Neuropsychopharmacology. 2011;36:1073-89 pubmed publisher
Han H, Sellamuthu S, Shin B, Lee Y, Song S, Seo J, et al. The nuclear inclusion a (NIa) protease of turnip mosaic virus (TuMV) cleaves amyloid-?. PLoS ONE. 2010;5:e15645 pubmed publisher
Wang C, Wang T, Zheng W, Zhao B, Danscher G, Chen Y, et al. Zinc overload enhances APP cleavage and A? deposition in the Alzheimer mouse brain. PLoS ONE. 2010;5:e15349 pubmed publisher
Jordão J, Ayala Grosso C, Markham K, Huang Y, Chopra R, McLaurin J, et al. Antibodies targeted to the brain with image-guided focused ultrasound reduces amyloid-beta plaque load in the TgCRND8 mouse model of Alzheimer's disease. PLoS ONE. 2010;5:e10549 pubmed publisher
Seo J, Yun J, Baek I, Leem Y, Kang H, Cho H, et al. Oriental medicine Jangwonhwan reduces Abeta(1-42) level and beta-amyloid deposition in the brain of Tg-APPswe/PS1dE9 mouse model of Alzheimer disease. J Ethnopharmacol. 2010;128:206-12 pubmed publisher
Lee K, Kim J, Seo J, Kim T, Im J, Baek I, et al. Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress. J Neurochem. 2009;108:165-75 pubmed publisher
Sun A, Koelsch G, Tang J, Bing G. Localization of beta-secretase memapsin 2 in the brain of Alzheimer's patients and normal aged controls. Exp Neurol. 2002;175:10-22 pubmed
Tanzi R, McClatchey A, Lamperti E, Villa Komaroff L, Gusella J, Neve R. Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature. 1988;331:528-30 pubmed
Kang J, Lemaire H, Unterbeck A, Salbaum J, Masters C, Grzeschik K, et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature. 1987;325:733-6 pubmed
product information
Product No. :
A5213
Product Name :
Monoclonal Anti-β-Amyloid antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
BAM-10
Applications/Description :
Suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:2,000 using formic acid-treated, formalin-fixed, human Alzheimer′s disease (AD) brain sections.; indirect ELISA
Species Reactivity :
human
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA