This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Adenosine Deaminase from bovine spleen
catalog :
A5168
citations: 54
Reference
Bielsa S, Esquerda A, Palma R, Criado A, Porcel J. Influence of storage time on pleural fluid adenosine deaminase activity. Clin Lab. 2014;60:501-4 pubmed
Saccucci P, Binczak Kuleta A, Banci M, Krzysztalowska M, Dofcaci A, Safranow K, et al. Coronary artery disease. A study of three polymorphic sites of adenosine deaminase gene. Acta Cardiol. 2014;69:39-44 pubmed
Islam A, Hossain M, Paul S, Bhuiyan M, Khan R, Rahman M, et al. Role of adenosine deaminase in diagnosis of tubercular pleural effusion. Mymensingh Med J. 2014;23:24-7 pubmed
Navon Elkan P, Pierce S, Segel R, Walsh T, Barash J, Padeh S, et al. Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy. N Engl J Med. 2014;370:921-31 pubmed publisher
Zhou Q, Yang D, Ombrello A, Zavialov A, Toro C, Zavialov A, et al. Early-onset stroke and vasculopathy associated with mutations in ADA2. N Engl J Med. 2014;370:911-20 pubmed publisher
Brigida I, Sauer A, Ferrua F, Giannelli S, Scaramuzza S, Pistoia V, et al. B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients. J Allergy Clin Immunol. 2014;133:799-806.e10 pubmed publisher
Reenan R. Correcting mutations by RNA repair. N Engl J Med. 2014;370:172-4 pubmed publisher
Qin Y, Qiao J, Chan T, Zhu Y, Li F, Liu H, et al. Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma. Cancer Res. 2014;74:840-51 pubmed publisher
Bonello L, Laine M, Kipson N, Mancini J, Helal O, Fromonot J, et al. Ticagrelor increases adenosine plasma concentration in patients with an acute coronary syndrome. J Am Coll Cardiol. 2014;63:872-7 pubmed publisher
Raj V, Smits S, Provacia L, van den Brand J, Wiersma L, Ouwendijk W, et al. Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus. J Virol. 2014;88:1834-8 pubmed publisher
Sarvestani S, Tate M, Moffat J, Jacobi A, Behlke M, Miller A, et al. Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8. J Virol. 2014;88:799-810 pubmed publisher
Krageloh Mann I. Characterisation of Aicardi-Goutières syndrome. Lancet Neurol. 2013;12:1131-2 pubmed publisher
Rice G, Forte G, Szynkiewicz M, Chase D, Aeby A, Abdel Hamid M, et al. Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study. Lancet Neurol. 2013;12:1159-69 pubmed publisher
Donnelly C, Zhang P, Pham J, Haeusler A, Heusler A, Mistry N, et al. RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron. 2013;80:415-28 pubmed publisher
Li X, Overton I, Baines R, Keegan L, O Connell M. The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster. Nucleic Acids Res. 2014;42:1139-51 pubmed publisher
Eifler T, Pokharel S, Beal P. RNA-Seq analysis identifies a novel set of editing substrates for human ADAR2 present in Saccharomyces cerevisiae. Biochemistry. 2013;52:7857-69 pubmed publisher
Gaspar H, Qasim W, Davies E, Rao K, Amrolia P, Veys P. How I treat severe combined immunodeficiency. Blood. 2013;122:3749-58 pubmed publisher
Montiel Gonzalez M, Vallecillo Viejo I, Yudowski G, Rosenthal J. Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing. Proc Natl Acad Sci U S A. 2013;110:18285-90 pubmed publisher
Kashyap R, Nayak A, Gaherwar H, Bhullar S, Husain A, Shekhawat S, et al. Laboratory investigations on the diagnosis of tuberculosis in the malnourished tribal population of melghat, India. PLoS ONE. 2013;8:e74652 pubmed publisher
Wang Q, Hui H, Guo Z, Zhang W, Hu Y, He T, et al. ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding. RNA. 2013;19:1525-36 pubmed publisher
Sugden L, Tackett M, Savva Y, Thompson W, Lawrence C. Assessing the validity and reproducibility of genome-scale predictions. Bioinformatics. 2013;29:2844-51 pubmed publisher
Mete R, Tulubas F, Oran M, Yılmaz A, Avci B, Yildiz K, et al. The role of oxidants and reactive nitrogen species in irritable bowel syndrome: a potential etiological explanation. Med Sci Monit. 2013;19:762-6 pubmed publisher
Yang Y, Zhou X, Jin Y. ADAR-mediated RNA editing in non-coding RNA sequences. Sci China Life Sci. 2013;56:944-52 pubmed publisher
Karakeci A, Firdolas F, Ozan T, Unus I, Ogras M, Orhan I. Second pathways in the pathophysiology of ischemic priapism and treatment alternatives. Urology. 2013;82:625-9 pubmed publisher
Ng S, Weissbach R, Ronson G, Scadden A. Proteins that contain a functional Z-DNA-binding domain localize to cytoplasmic stress granules. Nucleic Acids Res. 2013;41:9786-99 pubmed publisher
Ota H, Sakurai M, Gupta R, Valente L, Wulff B, Ariyoshi K, et al. ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing. Cell. 2013;153:575-89 pubmed publisher
García López J, Hourcade J, del Mazo J. Reprogramming of microRNAs by adenosine-to-inosine editing and the selective elimination of edited microRNA precursors in mouse oocytes and preimplantation embryos. Nucleic Acids Res. 2013;41:5483-93 pubmed publisher
Solomon O, Oren S, Safran M, Deshet Unger N, Akiva P, Jacob Hirsch J, et al. Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR). RNA. 2013;19:591-604 pubmed publisher
Haddad E, Leroy S, Buckley R. B-cell reconstitution for SCID: should a conditioning regimen be used in SCID treatment?. J Allergy Clin Immunol. 2013;131:994-1000 pubmed publisher
Weng T, Karmouty Quintana H, Garcia Morales L, Molina J, Pedroza M, Bunge R, et al. Hypoxia-induced deoxycytidine kinase expression contributes to apoptosis in chronic lung disease. FASEB J. 2013;27:2013-26 pubmed publisher
Zhou W, Karcher D, Bock R. Importance of adenosine-to-inosine editing adjacent to the anticodon in an Arabidopsis alanine tRNA under environmental stress. Nucleic Acids Res. 2013;41:3362-72 pubmed publisher
Trincavelli M. Unveiling the binding mode of adenosine deaminase inhibitors to the active site of the enzyme: implication for rational drug design : presented by Maria P. Abbracchio. Purinergic Signal. 2013;9:1-3 pubmed publisher
Nomura K, Hoshino A, Miyawaki T, Hama A, Kojima S, Kanegane H. Neutropenia and myeloid dysplasia in a patient with delayed-onset adenosine deaminase deficiency. Pediatr Blood Cancer. 2013;60:885-6 pubmed publisher
Lee Y, Kim H, Lee E, Seo Y, Lee A, Lee J. NMR investigation on the DNA binding and B-Z transition pathway of the Zα domain of human ADAR1. Biophys Chem. 2013;172:18-25 pubmed publisher
Lu Q, Sakhatskyy P, Newton J, Shamirian P, Hsiao V, Curren S, et al. Sustained adenosine exposure causes lung endothelial apoptosis: a possible contributor to cigarette smoke-induced endothelial apoptosis and lung injury. Am J Physiol Lung Cell Mol Physiol. 2013;304:L361-70 pubmed publisher
Chen L, Lin C, Chan T, Chow R, Song Y, Liu M, et al. Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma. Nat Med. 2013;19:209-16 pubmed publisher
Ohta M, Toyama K, Gutterman D, Campbell W, Lemaitre V, Teraoka R, et al. Ecto-5'-nucleotidase, CD73, is an endothelium-derived hyperpolarizing factor synthase. Arterioscler Thromb Vasc Biol. 2013;33:629-36 pubmed publisher
Tariq A, Garncarz W, Handl C, Balik A, Pusch O, Jantsch M. RNA-interacting proteins act as site-specific repressors of ADAR2-mediated RNA editing and fluctuate upon neuronal stimulation. Nucleic Acids Res. 2013;41:2581-93 pubmed publisher
Jiang Q, Crews L, Barrett C, Chun H, Court A, Isquith J, et al. ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proc Natl Acad Sci U S A. 2013;110:1041-6 pubmed publisher
Li L, Mizel D, Huang Y, Eisner C, Hoerl M, Thiel M, et al. Tubuloglomerular feedback and renal function in mice with targeted deletion of the type 1 equilibrative nucleoside transporter. Am J Physiol Renal Physiol. 2013;304:F382-9 pubmed publisher
Fargo J, Kratz C, Giri N, Savage S, Wong C, Backer K, et al. Erythrocyte adenosine deaminase: diagnostic value for Diamond-Blackfan anaemia. Br J Haematol. 2013;160:547-54 pubmed publisher
Pérez Aguilar M, Goncalves L, Bonfante Cabarcas R. [Adenosine deaminase in severe combined immunodeficiency syndrome]. Invest Clin. 2012;53:315-24 pubmed
Casanova V, Naval Macabuhay I, Massanella M, Rodríguez García M, Blanco J, Gatell J, et al. Adenosine deaminase enhances the immunogenicity of human dendritic cells from healthy and HIV-infected individuals. PLoS ONE. 2012;7:e51287 pubmed publisher
Odewabi A, Ogundahunsi O, Odewabi A, Oritogun K, Ekor M. Adenosine deaminase activity and immunoglobulin levels as potential systemic biomonitors of occupational hazards and health status in municipal solid waste management workers. Environ Toxicol Pharmacol. 2013;35:1-12 pubmed publisher
Liz R, Zanatta L, dos Reis G, Horst H, Pizzolatti M, Silva F, et al. Acute effect of ?-sitosterol on calcium uptake mediates anti-inflammatory effect in murine activated neutrophils. J Pharm Pharmacol. 2013;65:115-22 pubmed publisher
Tsuruoka N, Arima M, Yoshida N, Okada S, Sakamoto A, Hatano M, et al. ADAR1 protein induces adenosine-targeted DNA mutations in senescent Bcl6 gene-deficient cells. J Biol Chem. 2013;288:826-36 pubmed publisher
Gracia E, Farré D, Cortés A, Ferrer Costa C, Orozco M, Mallol J, et al. The catalytic site structural gate of adenosine deaminase allosterically modulates ligand binding to adenosine receptors. FASEB J. 2013;27:1048-61 pubmed publisher
Thompson G, Sharma S, Bays D, Pruitt R, Engelthaler D, Bowers J, et al. Coccidioidomycosis: adenosine deaminase levels, serologic parameters, culture results, and polymerase chain reaction testing in pleural fluid. Chest. 2013;143:776-781 pubmed publisher
Antonangelo L, Vargas F, Puka J, Seiscento M, Acencio M, Teixeira L, et al. Pleural tuberculosis: is radiological evidence of pulmonary-associated disease related to the exacerbation of the inflammatory response?. Clinics (Sao Paulo). 2012;67:1259-63 pubmed
Zanini D, Schmatz R, Pelinson L, Pimentel V, da Costa P, Cardoso A, et al. Ectoenzymes and cholinesterase activity and biomarkers of oxidative stress in patients with lung cancer. Mol Cell Biochem. 2013;374:137-48 pubmed publisher
Cheng Y, Meng Q, Wang C, Li H, Huang Z, Chen S, et al. Leucine deprivation decreases fat mass by stimulation of lipolysis in white adipose tissue and upregulation of uncoupling protein 1 (UCP1) in brown adipose tissue. Diabetes. 2010;59:17-25 pubmed publisher
Tumati S, Yamamura H, Vanderah T, Roeske W, Varga E. Sustained morphine treatment augments capsaicin-evoked calcitonin gene-related peptide release from primary sensory neurons in a protein kinase A- and Raf-1-dependent manner. J Pharmacol Exp Ther. 2009;330:810-7 pubmed publisher
Kaplan N, Colowick S, CIOTTI M. Enzymatic deamination of adenosine derivatives. J Biol Chem. 1952;194:579-91 pubmed
Powell J, Hunter J. Adenosine deaminase and ribosidase in spores of Bacillus cereus. Biochem J. 1956;62:381-7 pubmed
product information
Catalog Number :
A5168
Product Name :
Adenosine Deaminase from bovine spleen
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
Type IX, ammonium sulfate suspension, 150-200 units/mg protein
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA