This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
other
product name :
6-Thioguanine
catalog :
A4660
citations: 66
Reference
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de Boer N, van Asseldonk D, Seinen M, van Bodegraven A. Oxidation-mediated DNA crosslinking contributes to toxicity of 6-thioguanine in human cells -- letter. Cancer Res. 2013;73:1445 pubmed publisher
Angelberger S, Schaeffeler E, Teml A, Petritsch W, Shonova O, Lukas M, et al. Mucosal improvement in patients with moderate to severe postoperative endoscopic recurrence of Crohn's disease and azathioprine metabolite levels. Inflamm Bowel Dis. 2013;19:590-8 pubmed publisher
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You C, Dai X, Yuan B, Wang Y. Effects of 6-thioguanine and S6-methylthioguanine on transcription in vitro and in human cells. J Biol Chem. 2012;287:40915-23 pubmed publisher
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Tang B, Testa J, Kruger W. Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells. Cancer Biol Ther. 2012;13:1082-90 pubmed publisher
Brem R, Karran P. Oxidation-mediated DNA cross-linking contributes to the toxicity of 6-thioguanine in human cells. Cancer Res. 2012;72:4787-95 pubmed publisher
Brem R, Karran P. Multiple forms of DNA damage caused by UVA photoactivation of DNA 6-thioguanine. Photochem Photobiol. 2012;88:5-13 pubmed publisher
Seinen M, van Asseldonk D, Mulder C, de Boer N. Dosing 6-thioguanine in inflammatory bowel disease: expert-based guidelines for daily practice. J Gastrointestin Liver Dis. 2010;19:291-4 pubmed
Fakhoury M, de Beaumais T, Medard Y, Jacqz Aigrain E. [Therapeutic drug monitoring of 6-thioguanine nucleotides in paediatric acute lymphoblastic leukaemia: interest and limits]. Therapie. 2010;65:187-93 pubmed publisher
Jourdil N, Fonrose X, Boulieu R, Stanke Labesque F. [Therapeutic drug monitoring of 6-thioguanine nucleotides in inflammatory bowel disease: interest and limits]. Therapie. 2010;65:177-86 pubmed publisher
Bendaly J, Doll M, Millner L, Metry K, Smith N, Pierce W, et al. Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations. Mutat Res. 2009;671:13-9 pubmed publisher
de Boer N, Reinisch W, Teml A, van Bodegraven A, Schwab M, Lukas M, et al. 6-Thioguanine treatment in inflammatory bowel disease: a critical appraisal by a European 6-TG working party. Digestion. 2006;73:25-31 pubmed
de Boer N, van Nieuwkerk C, Aparicio Pages M, de Boer S, Derijks L, Mulder C. Promising treatment of autoimmune hepatitis with 6-thioguanine after adverse events on azathioprine. Eur J Gastroenterol Hepatol. 2005;17:457-61 pubmed
Schwab M, Herrlinger K, Schaeffeler E, Stange E. [Therapy of chronic inflammatory bowel diseases with azathioprine, 6-mercaptopurine and 6-thioguanine. Clinico-pharmacologic aspects]. Dtsch Med Wochenschr. 2003;128:378-85 pubmed
Sherer D, Lebwohl M. 6-thioguanine in the treatment of psoriasis: a case report and literature review. J Cutan Med Surg. 2002;6:546-50 pubmed
Estlin E. Continuing therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of methotrexate, 6-mercaptopurine and 6-thioguanine. Cancer Treat Rev. 2001;27:351-63 pubmed
product information
Catalog Number :
A4660
Product Name :
6-Thioguanine
Product Type :
CELL CULTURE REAGENT
Product Group :
Cell Biology
Product Description :
Hybri-Max™, 50 ×, ?-irradiated, lyophilized powder, BioXtra, suitable for hybridoma
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA