This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Actin antibody produced in mouse
catalog :
A3853
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AC-40
reactivity :
human, mouse, rat, dogs, chicken, zebrafish , Xenopus laevis
application :
western blot, immunocytochemistry, immunoprecipitation, other
citations: 426
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2a
González Rodríguez P, Engskog Vlachos P, Zhang H, Murgoci A, Zerdes I, Joseph B. SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12. Cell Death Dis. 2020;11:69 pubmed publisher
  • western blot; mouse; 1:20,000; loading ...; fig 4e
Even A, Morelli G, Broix L, Scaramuzzino C, Turchetto S, Gladwyn Ng I, et al. ATAT1-enriched vesicles promote microtubule acetylation via axonal transport. Sci Adv. 2019;5:eaax2705 pubmed publisher
  • western blot; human; loading ...; fig 3c
Ast T, Meisel J, Patra S, Wang H, Grange R, Kim S, et al. Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Cell. 2019;: pubmed publisher
  • western blot; human; loading ...; fig s3a
Urata S, Kenyon E, Nayak D, Cubitt B, Kurosaki Y, Yasuda J, et al. BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection. PLoS Pathog. 2018;14:e1007172 pubmed publisher
  • western blot; mouse; 1:10,000; loading ...; fig 1c
Barbero Camps E, Roca Agujetas V, Bartolessis I, de Dios C, Fernandez Checa J, Mari M, et al. Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion. Autophagy. 2018;14:1129-1154 pubmed publisher
  • western blot; human; 1:10,000
Pourcelot M, Zemirli N, Silva da Costa L, Loyant R, Garcin D, Vitour D, et al. The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing. BMC Biol. 2016;14:69 pubmed publisher
  • western blot; human; fig 2
Surtees R, Dowall S, Shaw A, Armstrong S, Hewson R, Carroll M, et al. Heat Shock Protein 70 Family Members Interact with Crimean-Congo Hemorrhagic Fever Virus and Hazara Virus Nucleocapsid Proteins and Perform a Functional Role in the Nairovirus Replication Cycle. J Virol. 2016;90:9305-16 pubmed publisher
  • western blot; mouse; 1:2000; fig 2a
Hammers D, Sleeper M, Forbes S, Shima A, Walter G, Sweeney H. Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts. J Am Heart Assoc. 2016;5: pubmed publisher
  • western blot; human; 1:3000; fig s3
Dorland Y, Malinova T, van Stalborch A, Grieve A, van Geemen D, Jansen N, et al. The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions. Nat Commun. 2016;7:12210 pubmed publisher
  • western blot; human; fig 2
Lu R, Hu X, Zhou J, Sun J, Zhu A, Xu X, et al. COPS5 amplification and overexpression confers tamoxifen-resistance in ER?-positive breast cancer by degradation of NCoR. Nat Commun. 2016;7:12044 pubmed publisher
  • western blot; human; 1:2000; fig 3
Ikeuchi M, Fukumoto Y, Honda T, Kuga T, Saito Y, Yamaguchi N, et al. v-Src Causes Chromosome Bridges in a Caffeine-Sensitive Manner by Generating DNA Damage. Int J Mol Sci. 2016;17: pubmed publisher
  • western blot; mouse; 1:10,000; fig 4
  • western blot; human; 1:10,000; fig 5
Speer S, Li Z, Buta S, Payelle Brogard B, Qian L, Vigant F, et al. ISG15 deficiency and increased viral resistance in humans but not mice. Nat Commun. 2016;7:11496 pubmed publisher
  • western blot; human; 1:500; fig 2
Pethő Z, Tanner M, Tajhya R, Huq R, Laragione T, Panyi G, et al. Different expression of ? subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes. Arthritis Res Ther. 2016;18:103 pubmed publisher
  • western blot; human; fig 4
Gandolfi B, Alamri S, Darby W, Adhikari B, Lattimer J, Malik R, et al. A dominant TRPV4 variant underlies osteochondrodysplasia in Scottish fold cats. Osteoarthritis Cartilage. 2016;24:1441-50 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Körber N, Stein V. In vivo imaging demonstrates dendritic spine stabilization by SynCAM 1. Sci Rep. 2016;6:24241 pubmed publisher
  • western blot; human; fig 3
Jiang L, Shestov A, Swain P, Yang C, Parker S, Wang Q, et al. Reductive carboxylation supports redox homeostasis during anchorage-independent growth. Nature. 2016;532:255-8 pubmed publisher
  • western blot; mouse; 1:10,000; fig s6
Hattori K, Naguro I, Okabe K, Funatsu T, Furutani S, Takeda K, et al. ASK1 signalling regulates brown and beige adipocyte function. Nat Commun. 2016;7:11158 pubmed publisher
  • western blot; mouse; loading ...; fig 4d
Li T, Liu X, Jiang L, MANFREDI J, Zha S, Gu W. Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging. Oncotarget. 2016;7:11838-49 pubmed publisher
  • western blot; human; 1:1000; fig s1
Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, et al. F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling. Nat Commun. 2016;7:10493 pubmed publisher
  • western blot; rat; 1:5000; fig 2
Torres G, Morales P, García Miguel M, Norambuena Soto I, Cartes Saavedra B, Vidal Peña G, et al. Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation. Biochem Pharmacol. 2016;104:52-61 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; human; fig 3
Suzuki Y, Chin W, Han Q, Ichiyama K, Lee C, Eyo Z, et al. Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication. PLoS Pathog. 2016;12:e1005357 pubmed publisher
  • western blot; mouse; 1:30,000; fig 1
Quesseveur G, Portal B, Basile J, Ezan P, Mathou A, Halley H, et al. Attenuated Levels of Hippocampal Connexin 43 and its Phosphorylation Correlate with Antidepressant- and Anxiolytic-Like Activities in Mice. Front Cell Neurosci. 2015;9:490 pubmed publisher
  • western blot; human; fig 1a
Hrstka R, Bouchalova P, Michalová E, Matoulkova E, Muller P, Coates P, et al. AGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10-mediated regulatory pathway. Mol Oncol. 2016;10:652-62 pubmed publisher
  • western blot; chicken; 1:6000; fig 9
Nielsen C, Huttner D, Bizard A, Hirano S, Li T, Palmai Pallag T, et al. PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis. Nat Commun. 2015;6:8962 pubmed publisher
  • western blot; dogs; 1:1000; fig 2
Kim Y, Jo S, Kim W, Kweon O. Antioxidant and anti-inflammatory effects of intravenously injected adipose derived mesenchymal stem cells in dogs with acute spinal cord injury. Stem Cell Res Ther. 2015;6:229 pubmed publisher
  • western blot; human; fig 2
Han X, Liu Z, Jo M, Zhang K, Li Y, Zeng Z, et al. CRISPR-Cas9 delivery to hard-to-transfect cells via membrane deformation. Sci Adv. 2015;1:e1500454 pubmed publisher
  • western blot; mouse; loading ...; fig 7
Alnasser H, Guan Q, Zhang F, Gleave M, Nguan C, Du C. Requirement of clusterin expression for prosurvival autophagy in hypoxic kidney tubular epithelial cells. Am J Physiol Renal Physiol. 2016;310:F160-73 pubmed publisher
  • western blot; rat; 1:5000; fig 3
  • western blot; mouse; 1:5000; fig 1
Zhang P, Fu W, Fu A, Ip N. S-nitrosylation-dependent proteasomal degradation restrains Cdk5 activity to regulate hippocampal synaptic strength. Nat Commun. 2015;6:8665 pubmed publisher
  • western blot; mouse; fig s7
Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed publisher
  • western blot; human; 1:1000; fig 2
Min M, Mevissen T, De Luca M, Komander D, Lindon C. Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages. Mol Biol Cell. 2015;26:4325-32 pubmed publisher
  • western blot; Xenopus laevis; 1:800; fig 3
Dubińska Magiera M, Chmielewska M, Kozioł K, Machowska M, Hutchison C, Goldberg M, et al. Xenopus LAP2β protein knockdown affects location of lamin B and nucleoporins and has effect on assembly of cell nucleus and cell viability. Protoplasma. 2016;253:943-56 pubmed publisher
  • western blot; human; fig 1b
Sloan E, Tatham M, Groslambert M, Glass M, Orr A, Hay R, et al. Analysis of the SUMO2 Proteome during HSV-1 Infection. PLoS Pathog. 2015;11:e1005059 pubmed publisher
  • western blot; human
Fufa T, Byun J, Wakano C, Fernandez A, Pise Masison C, Gardner K. The Tax oncogene enhances ELL incorporation into p300 and P-TEFb containing protein complexes to activate transcription. Biochem Biophys Res Commun. 2015;465:5-11 pubmed publisher
  • western blot; mouse; 1:10000
Chugh D, Ali I, Bakochi A, Bahonjic E, Etholm L, Ekdahl C. Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2. PLoS ONE. 2015;10:e0132366 pubmed publisher
  • western blot; rat; fig 3
Khan M, Dhammu T, Matsuda F, Singh A, Singh I. Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy. BMC Neurosci. 2015;16:42 pubmed publisher
  • western blot; human; fig 1
Verma S, Mohapatra G, Ahmad S, Rana S, Jain S, Khalsa J, et al. Salmonella Engages Host MicroRNAs To Modulate SUMOylation: a New Arsenal for Intracellular Survival. Mol Cell Biol. 2015;35:2932-46 pubmed publisher
  • western blot; human; 1:1000; fig s5
Mercer J, Argus J, Crabtree D, KEENAN M, Wilks M, Chi J, et al. Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis. PLoS ONE. 2015;10:e0129776 pubmed publisher
  • western blot; human; 1:5000; fig 4
Barr A, Bakal C. A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep. 2015;5:10564 pubmed publisher
  • western blot; human
Tatti M, Motta M, Scarpa S, Di Bartolomeo S, Cianfanelli V, Tartaglia M, et al. BCM-95 and (2-hydroxypropyl)-β-cyclodextrin reverse autophagy dysfunction and deplete stored lipids in Sap C-deficient fibroblasts. Hum Mol Genet. 2015;24:4198-211 pubmed publisher
  • western blot; human
Sechler M, Borowicz S, Van Scoyk M, Avasarala S, Zerayesus S, Edwards M, et al. Novel Role for γ-Catenin in the Regulation of Cancer Cell Migration via the Induction of Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1). J Biol Chem. 2015;290:15610-20 pubmed publisher
  • western blot; mouse
Randles M, Woolf A, Huang J, Byron A, Humphries J, Price K, et al. Genetic Background is a Key Determinant of Glomerular Extracellular Matrix Composition and Organization. J Am Soc Nephrol. 2015;26:3021-34 pubmed publisher
  • western blot; human; fig 4
Hotokezaka Y, Katayama I, van Leyen K, Nakamura T. GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses. Cell Death Dis. 2015;6:e1719 pubmed publisher
  • western blot; human; 1:500; fig 8
Okatsu K, Koyano F, Kimura M, Kosako H, Saeki Y, Tanaka K, et al. Phosphorylated ubiquitin chain is the genuine Parkin receptor. J Cell Biol. 2015;209:111-28 pubmed publisher
  • western blot; mouse; fig 1
Hashimoto T, Chen L, Kimura H, Endler A, Koyama H, Miyata T, et al. Silencing of eIF3e promotes blood perfusion recovery after limb ischemia through stabilization of hypoxia-inducible factor 2α activity. J Vasc Surg. 2016;64:219-226.e3 pubmed publisher
  • western blot; mouse; 1:1000
Sabogal Guáqueta A, Muñoz Manco J, Ramírez Pineda J, Lamprea Rodriguez M, Osorio E, Cardona Gómez G. The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice. Neuropharmacology. 2015;93:134-45 pubmed publisher
  • western blot; mouse; fig s5
Fuji R, Flagella M, Baca M, Baptista M, Brodbeck J, Chan B, et al. Effect of selective LRRK2 kinase inhibition on nonhuman primate lung. Sci Transl Med. 2015;7:273ra15 pubmed publisher
  • western blot; human; fig s3
Gibbs Seymour I, Markiewicz E, Bekker Jensen S, Mailand N, Hutchison C. Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage. Aging Cell. 2015;14:162-9 pubmed publisher
  • western blot; human; fig 1
Cho S, Yun S, Jo C, Lee D, Choi K, Song J, et al. SUMO1 promotes Aβ production via the modulation of autophagy. Autophagy. 2015;11:100-12 pubmed publisher
  • western blot; human
Giovannini C, Minguzzi M, Baglioni M, Fornari F, Giannone F, Ravaioli M, et al. Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma. Oncotarget. 2014;5:10607-20 pubmed
  • western blot; mouse; 1:20000
Bernard Marissal N, Sunyach C, Marissal T, Raoul C, Pettmann B. Calreticulin levels determine onset of early muscle denervation by fast motoneurons of ALS model mice. Neurobiol Dis. 2015;73:130-6 pubmed publisher
  • western blot; human; fig 6
Zhang X, Ma W, Cui J, Yao H, Zhou H, Ge Y, et al. Regulation of p21 by TWIST2 contributes to its tumor-suppressor function in human acute myeloid leukemia. Oncogene. 2015;34:3000-10 pubmed publisher
  • western blot; human; 1:2000
Althoff K, Lindner S, Odersky A, Mestdagh P, Beckers A, Karczewski S, et al. miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin. Int J Cancer. 2015;136:1308-20 pubmed publisher
  • western blot; human
Doceul V, Chauveau E, Lara E, Breard E, Sailleau C, Zientara S, et al. Dual modulation of type I interferon response by bluetongue virus. J Virol. 2014;88:10792-802 pubmed publisher
  • western blot; mouse; fig 4
Schroder W, Major L, Le T, Gardner J, Sweet M, Janciauskiene S, et al. Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis. Cancer Med. 2014;3:500-13 pubmed publisher
  • western blot; mouse; 1:2500; fig 1
Zhang Y, Chen L, Shen G, Zhao Q, Shangguan L, He M. GRK5 dysfunction accelerates tau hyperphosphorylation in APP (swe) mice through impaired cholinergic activity. Neuroreport. 2014;25:542-7 pubmed publisher
  • western blot; human
Boin A, Couvelard A, Couderc C, Brito I, Filipescu D, Kalamarides M, et al. Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas. Neuro Oncol. 2014;16:1196-209 pubmed publisher
  • western blot; human
Zhou X, Han X, Zhao K, Du J, Evans S, Wang H, et al. Dispersed and conserved hydrophobic residues of HIV-1 Vif are essential for CBF? recruitment and A3G suppression. J Virol. 2014;88:2555-63 pubmed publisher
  • immunoprecipitation; human
  • immunocytochemistry; human
  • western blot; human
Bi J, Wang R, Zhang Y, Han X, Ampah K, Liu W, et al. Identification of nucleolin as a lipid-raft-dependent ?1-integrin-interacting protein in A375 cell migration. Mol Cells. 2013;36:507-17 pubmed publisher
  • western blot; mouse; 1:25000
Chastre A, Belanger M, Nguyen B, Butterworth R. Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure. Liver Int. 2014;34:353-61 pubmed publisher
  • western blot; rat; 1:250; fig 4
Gonzalez Silva C, Vera J, Bono M, Gonzalez Billault C, Baxter B, Hansen A, et al. Ca2+-activated Cl- channels of the ClCa family express in the cilia of a subset of rat olfactory sensory neurons. PLoS ONE. 2013;8:e69295 pubmed publisher
  • western blot; rat
Murata Y, Constantine Paton M. Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway. J Neurosci. 2013;33:5040-52 pubmed publisher
  • western blot; zebrafish ; 1:1000
Chen Y, Sundvik M, Rozov S, Priyadarshini M, Panula P. MANF regulates dopaminergic neuron development in larval zebrafish. Dev Biol. 2012;370:237-49 pubmed publisher
Willoughby J, George K, Roberto M, Chin H, Stoiber P, Shin H, et al. Targeting the oncogene LSF with either the small molecule inhibitor FQI1 or siRNA causes mitotic delays with unaligned chromosomes, resulting in cell death or senescence. BMC Cancer. 2020;20:552 pubmed publisher
Elsworthy R, Aldred S. The effect of age and obesity on platelet amyloid precursor protein processing and plasma markers of oxidative stress and inflammation. Exp Gerontol. 2020;132:110838 pubmed publisher
Li Y, Yin Y, Ma J, Sun Y, Zhou R, Cui B, et al. Combination of AAV‑mediated NUPR1 knockdown and trifluoperazine induces premature senescence in human lung adenocarcinoma A549 cells in nude mice. Oncol Rep. 2020;43:681-688 pubmed publisher
Lindahl M, CHALAZONITIS A, Palm E, Pakarinen E, Danilova T, Pham T, et al. Cerebral dopamine neurotrophic factor-deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice. Neurobiol Dis. 2020;134:104696 pubmed publisher
Jubrail J, Africano Gomez K, Herit F, Mularski A, Bourdoncle P, Oberg L, et al. Arpin is critical for phagocytosis in macrophages and is targeted by human rhinovirus. EMBO Rep. 2020;21:e47963 pubmed publisher
Feng Q, Luo Y, Zhang X, Yang X, Hong X, Sun D, et al. MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration. Autophagy. 2020;16:641-658 pubmed publisher
De Silva D, Zhang Z, Liu Y, Parker J, Xu C, Cai L, et al. Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen. Sci Rep. 2019;9:18637 pubmed publisher
Yuan H, Wu G, Zhai X, Lu B, Meng B, Chen J. Melatonin and Rapamycin Attenuate Isoflurane-Induced Cognitive Impairment Through Inhibition of Neuroinflammation by Suppressing the mTOR Signaling in the Hippocampus of Aged Mice. Front Aging Neurosci. 2019;11:314 pubmed publisher
Li S, Hong X, Wei Z, Xie M, Li W, Liu G, et al. Ubiquitination of the HPV Oncoprotein E6 Is Critical for E6/E6AP-Mediated p53 Degradation. Front Microbiol. 2019;10:2483 pubmed publisher
Randzavola L, Strege K, Juzans M, Asano Y, Stinchcombe J, Gawden Bone C, et al. Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity. J Clin Invest. 2019;129:5600-5614 pubmed publisher
Boncompain G, Gareil N, Tessier S, Lescure A, Jones T, Kepp O, et al. BML-265 and Tyrphostin AG1478 Disperse the Golgi Apparatus and Abolish Protein Transport in Human Cells. Front Cell Dev Biol. 2019;7:232 pubmed publisher
Villalpando Rodriguez G, Blankstein A, Konzelman C, Gibson S. Lysosomal Destabilizing Drug Siramesine and the Dual Tyrosine Kinase Inhibitor Lapatinib Induce a Synergistic Ferroptosis through Reduced Heme Oxygenase-1 (HO-1) Levels. Oxid Med Cell Longev. 2019;2019:9561281 pubmed publisher
Avasarala S, Wu P, Khan S, Yanlin S, Van Scoyk M, Bao J, et al. PRMT6 Promotes Lung Tumor Progression via the Alternate Activation of Tumor-Associated Macrophages. Mol Cancer Res. 2019;: pubmed publisher
Dorland Y, Cornelissen A, Kuijk C, Tol S, Hoogenboezem M, van Buul J, et al. Nuclear shape, protrusive behaviour and in vivo retention of human bone marrow mesenchymal stromal cells is controlled by Lamin-A/C expression. Sci Rep. 2019;9:14401 pubmed publisher
Men L, Sun J, Luo G, Ren D. Acute Deletion of METTL14 in β-Cells of Adult Mice Results in Glucose Intolerance. Endocrinology. 2019;160:2388-2394 pubmed publisher
Wong M, Sun Y, Xi Z, Milazzo G, Poulos R, Bartenhagen C, et al. JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma. Nat Commun. 2019;10:3319 pubmed publisher
Pietri M, Djillani A, Mazella J, Borsotto M, Heurteaux C. First evidence of protective effects on stroke recovery and post-stroke depression induced by sortilin-derived peptides. Neuropharmacology. 2019;158:107715 pubmed publisher
Jiang S, Tang J, Xiao X, Qi W, Wu S, Jiang C, et al. Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase. PLoS Genet. 2019;15:e1008289 pubmed publisher
Duthie A, van Aalten L, MacDonald C, McNeilly A, Gallagher J, Geddes J, et al. Recruitment, Retainment, and Biomarkers of Response; A Pilot Trial of Lithium in Humans With Mild Cognitive Impairment. Front Mol Neurosci. 2019;12:163 pubmed publisher
Yoshihara T, Machida S, Tsuzuki T, Kakigi R, Chang S, Sugiura T, et al. Age-related changes in histone modification in rat gastrocnemius muscle. Exp Gerontol. 2019;125:110658 pubmed publisher
Kadigamuwa C, Choksi S, Xu Q, Cataisson C, Greenbaum S, Yuspa S, et al. Role of Retinoic Acid Receptor-γ in DNA Damage-Induced Necroptosis. iScience. 2019;17:74-86 pubmed publisher
Kumar H, Pushpa K, Kumari A, Verma K, Pergu R, Mylavarapu S. The Exocyst complex and Rab5 are required for abscission by localizing ESCRT III subunits to the cytokinetic bridge. J Cell Sci. 2019;: pubmed publisher
Morand J, Briançon Marjollet A, Lemarié E, Gonthier B, Arnaud J, Korichneva I, et al. Zinc deficiency promotes endothelin secretion and endothelial cell migration through nuclear hypoxia-inducible factor-1 translocation. Am J Physiol Cell Physiol. 2019;317:C270-C276 pubmed publisher
Lee Y, Chen M, Lee J, Zhang J, Lin S, Fu T, et al. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science. 2019;364: pubmed publisher
Ghimire K, Zaric J, Alday Parejo B, Seebach J, Bousquenaud M, Stalin J, et al. MAGI1 Mediates eNOS Activation and NO Production in Endothelial Cells in Response to Fluid Shear Stress. Cells. 2019;8: pubmed publisher
Liu J, Luo G, Sun J, Men L, Ye H, He C, et al. METTL14 is essential for β-cell survival and insulin secretion. Biochim Biophys Acta Mol Basis Dis. 2019;: pubmed publisher
Guo H, Zhang N, Shen S, Yu X, Wei W. Determinants of lentiviral Vpx-CRL4 E3 ligase-mediated SAMHD1 degradation in the substrate adaptor protein DCAF1. Biochem Biophys Res Commun. 2019;513:933-939 pubmed publisher
Prozorovski T, Ingwersen J, Lukas D, Göttle P, Koop B, Graf J, et al. Regulation of sirtuin expression in autoimmune neuroinflammation: Induction of SIRT1 in oligodendrocyte progenitor cells. Neurosci Lett. 2019;704:116-125 pubmed publisher
Ciminski K, Pulvermüller J, Adam J, Schwemmle M. Human MxA is a potent interspecies barrier for the novel bat-derived influenza A-like virus H18N11. Emerg Microbes Infect. 2019;8:556-563 pubmed publisher
Stumpf S, Berghoff S, Trevisiol A, Spieth L, Düking T, Schneider L, et al. Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease. Acta Neuropathol. 2019;138:147-161 pubmed publisher
Pergu R, Dagar S, Kumar H, Kumar R, Bhattacharya J, Mylavarapu S. The chaperone ERp29 is required for tunneling nanotube formation by stabilizing MSec. J Biol Chem. 2019;294:7177-7193 pubmed publisher
Murillo León M, Müller U, Zimmermann I, Singh S, Widdershooven P, Campos C, et al. Molecular mechanism for the control of virulent Toxoplasma gondii infections in wild-derived mice. Nat Commun. 2019;10:1233 pubmed publisher
Kluth O, Stadion M, Gottmann P, Aga H, Jähnert M, Scherneck S, et al. Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans. Cell Rep. 2019;26:3027-3036.e3 pubmed publisher
Mylavarapu S, Kumar H, Kumari S, Sravanthi L, Jain M, Basu A, et al. Activation of Epithelial-Mesenchymal Transition and Altered β-Catenin Signaling in a Novel Indian Colorectal Carcinoma Cell Line. Front Oncol. 2019;9:54 pubmed publisher
Yasuda J, Okada M, Yamawaki H. Protective effect of T3 peptide, an active fragment of tumstatin, against ischemia/reperfusion injury in rat heart. J Pharmacol Sci. 2019;139:193-200 pubmed publisher
Mosqueira M, Iturriaga R. Chronic hypoxia changes gene expression profile of primary rat carotid body cells: consequences on the expression of NOS isoforms and ET-1 receptors. Physiol Genomics. 2019;51:109-124 pubmed publisher
Nehls J, Businger R, Hoffmann M, Brinkmann C, Fehrenbacher B, Schaller M, et al. Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner. Cell Rep. 2019;26:1841-1853.e6 pubmed publisher
Trajkovic K, Valdez C, Ysselstein D, Krainc D. Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes. PLoS ONE. 2019;14:e0211727 pubmed publisher
Meyer K, Feldman H, Lu T, Drake D, Lim E, Ling K, et al. REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease. Cell Rep. 2019;26:1112-1127.e9 pubmed publisher
Galván Peña S, Carroll R, Newman C, Hinchy E, Palsson McDermott E, Robinson E, et al. Malonylation of GAPDH is an inflammatory signal in macrophages. Nat Commun. 2019;10:338 pubmed publisher
Davies S, Ballesteros Merino C, Allen N, Porch M, Pruitt M, Christensen K, et al. Impact of moderate prenatal alcohol exposure on histaminergic neurons, histidine decarboxylase levels and histamine H2 receptors in adult rat offspring. Alcohol. 2019;76:47-57 pubmed publisher
Chen M, Zhang J, Berger A, Diolombi M, Ng C, Fung J, et al. Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis. J Clin Invest. 2019;129:215-222 pubmed publisher
Murakami K, Etlinger J. Role of SMURF1 ubiquitin ligase in BMP receptor trafficking and signaling. Cell Signal. 2019;54:139-149 pubmed publisher
Miller D, Bloxham R, Jiang M, Gori I, Saunders R, Das D, et al. The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery. Cell Rep. 2018;25:1841-1855.e5 pubmed publisher
Wang D, Guo H, Chang J, Wang D, Liu B, Gao P, et al. Andrographolide Prevents EV-D68 Replication by Inhibiting the Acidification of Virus-Containing Endocytic Vesicles. Front Microbiol. 2018;9:2407 pubmed publisher
Swarts D, Stewart E, Higgins G, Coverley D. CIZ1-F, an alternatively spliced variant of the DNA replication protein CIZ1 with distinct expression and localisation, is overrepresented in early stage common solid tumours. Cell Cycle. 2018;17:2268-2283 pubmed publisher
Penfold L, Woods A, Muckett P, Nikitin A, Kent T, Zhang S, et al. CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis. Cancer Res. 2018;78:6747-6761 pubmed publisher
Park H, Park S, Mah S, Park J, Hong S, Hong S, et al. HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis. Exp Mol Med. 2018;50:125 pubmed publisher
Hartleben G, Muller C, Kramer A, Schimmel H, Zidek L, Dornblut C, et al. Tuberous sclerosis complex is required for tumor maintenance in MYC-driven Burkitt's lymphoma. EMBO J. 2018;37: pubmed publisher
Chéret J, Bertolini M, Ponce L, Lehmann J, Tsai T, Alam M, et al. Olfactory receptor OR2AT4 regulates human hair growth. Nat Commun. 2018;9:3624 pubmed publisher
Hsin J, Lu Y, Loeb G, Leslie C, Rudensky A. The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types. Nat Immunol. 2018;19:1137-1145 pubmed publisher
Otten C, Knox J, Boulday G, Eymery M, Haniszewski M, Neuenschwander M, et al. Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations. EMBO Mol Med. 2018;10: pubmed publisher
Balaji V, Kaniyappan S, Mandelkow E, Wang Y, Mandelkow E. Pathological missorting of endogenous MAPT/Tau in neurons caused by failure of protein degradation systems. Autophagy. 2018;14:2139-2154 pubmed publisher
Khan M, Dhammu T, Singh I, Singh A. Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity. BMC Neurosci. 2018;19:50 pubmed publisher
Arechederra M, Daian F, Yim A, Bazai S, Richelme S, Dono R, et al. Hypermethylation of gene body CpG islands predicts high dosage of functional oncogenes in liver cancer. Nat Commun. 2018;9:3164 pubmed publisher
Kim Y, Kang B, Kim W, Yun H, Kweon O. Evaluation of Mesenchymal Stem Cell Sheets Overexpressing BMP-7 in Canine Critical-Sized Bone Defects. Int J Mol Sci. 2018;19: pubmed publisher
Galindo L, Hernández Beeftink T, Salas A, Jung Y, Reyes R, de Oca F, et al. HMGA2 and MED12 alterations frequently co-occur in uterine leiomyomas. Gynecol Oncol. 2018;150:562-568 pubmed publisher
Huang X, Guo B, Liu S, Wan J, Broxmeyer H. Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment. Nat Commun. 2018;9:2741 pubmed publisher
Huang H, Zhang C, Wang B, Wang F, Pei B, Cheng C, et al. Transduction with Lentiviral Vectors Altered the Expression Profile of Host MicroRNAs. J Virol. 2018;92: pubmed publisher
Beránek V, Reinkemeier C, Zhang M, Liang A, Kym G, Chin J. Genetically Encoded Protein Phosphorylation in Mammalian Cells. Cell Chem Biol. 2018;25:1067-1074.e5 pubmed publisher
Jones M, Askari J, Humphries J, Humphries M. Cell adhesion is regulated by CDK1 during the cell cycle. J Cell Biol. 2018;217:3203-3218 pubmed publisher
Park S, Burke R, Kareva T, Kholodilov N, Aimé P, Franke T, et al. Context-dependent expression of a conditionally-inducible form of active Akt. PLoS ONE. 2018;13:e0197899 pubmed publisher
Sun J, Mao L, Yang H, Ren D. Critical role for the Tsc1-mTORC1 pathway in ?-cell mass in Pdx1-deficient mice. J Endocrinol. 2018;238:151-163 pubmed publisher
Morelli G, Even A, Gladwyn Ng I, Le Bail R, Shilian M, Godin J, et al. p27Kip1 Modulates Axonal Transport by Regulating ?-Tubulin Acetyltransferase 1 Stability. Cell Rep. 2018;23:2429-2442 pubmed publisher
Ward A, Kumari G, Sen R, Desiderio S. The RAG-2 Inhibitory Domain Gates Accessibility of the V(D)J Recombinase to Chromatin. Mol Cell Biol. 2018;38: pubmed publisher
Cuadrado E, van den Biggelaar M, de Kivit S, Chen Y, Slot M, Doubal I, et al. Proteomic Analyses of Human Regulatory T Cells Reveal Adaptations in Signaling Pathways that Protect Cellular Identity. Immunity. 2018;48:1046-1059.e6 pubmed publisher
Kinsella S, Fichtner M, Watters O, König H, Prehn J. Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation. J Neuroinflammation. 2018;15:130 pubmed publisher
Shiloh R, Gilad Y, Ber Y, Eisenstein M, Aweida D, Bialik S, et al. Non-canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy. Nat Commun. 2018;9:1759 pubmed publisher
Trotta M, Salerno M, Brigida A, Monda V, Messina A, Fiore C, et al. Inhibition of aldose-reductase-2 by a benzofuroxane derivative bf-5m increases the expression of kcne1, kcnq1 in high glucose cultured H9c2 cardiac cells and sudden cardiac death. Oncotarget. 2018;9:17257-17269 pubmed publisher
Bester A, Lee J, Chavez A, Lee Y, Nachmani D, Vora S, et al. An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance. Cell. 2018;173:649-664.e20 pubmed publisher
Rimessi A, Bezzerri V, Salvatori F, Tamanini A, Nigro F, Dechecchi M, et al. PLCB3 Loss of Function Reduces Pseudomonas aeruginosa-Dependent IL-8 Release in Cystic Fibrosis. Am J Respir Cell Mol Biol. 2018;59:428-436 pubmed publisher
Özer Ö, Bhowmick R, Liu Y, Hickson I. Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism. Oncotarget. 2018;9:15836-15846 pubmed publisher
Jelinek M, Balusikova K, Daniel P, Němcová Fürstová V, Kirubakaran P, Jacek M, et al. Substituents at the C3' and C3'N positions are critical for taxanes to overcome acquired resistance of cancer cells to paclitaxel. Toxicol Appl Pharmacol. 2018;347:79-91 pubmed publisher
Kumar A, Jovel J, López Orozco J, Limonta D, Airo A, Hou S, et al. Human Sertoli cells support high levels of Zika virus replication and persistence. Sci Rep. 2018;8:5477 pubmed publisher
Verkaik M, Oranje M, Abdurrachim D, Goebel M, Gam Z, Prompers J, et al. High Fibroblast Growth Factor 23 concentrations in experimental renal failure impair calcium handling in cardiomyocytes. Physiol Rep. 2018;6:e13591 pubmed publisher
Rizzi C, Tiberi A, Giustizieri M, Marrone M, Gobbo F, Carucci N, et al. NGF steers microglia toward a neuroprotective phenotype. Glia. 2018;66:1395-1416 pubmed publisher
Ingwersen J, De Santi L, Wingerath B, Graf J, Koop B, Schneider R, et al. Nimodipine confers clinical improvement in two models of experimental autoimmune encephalomyelitis. J Neurochem. 2018;: pubmed publisher
Loughran G, Firth A, Atkins J, Ivanov I. Translational autoregulation of BZW1 and BZW2 expression by modulating the stringency of start codon selection. PLoS ONE. 2018;13:e0192648 pubmed publisher
Gilbert C, Sztul E, Machamer C. Commonly used trafficking blocks disrupt ARF1 activation and the localization and function of specific Golgi proteins. Mol Biol Cell. 2018;29:937-947 pubmed publisher
Goncharov T, Hedayati S, Mulvihill M, Izrael Tomasevic A, Zobel K, Jeet S, et al. Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling. Mol Cell. 2018;69:551-565.e7 pubmed publisher
Moore K, Yağcı N, van Alphen F, Paolini N, Horos R, Held N, et al. Csde1 binds transcripts involved in protein homeostasis and controls their expression in an erythroid cell line. Sci Rep. 2018;8:2628 pubmed publisher
Loughran G, Jungreis I, Tzani I, Power M, Dmitriev R, Ivanov I, et al. Stop codon readthrough generates a C-terminally extended variant of the human vitamin D receptor with reduced calcitriol response. J Biol Chem. 2018;293:4434-4444 pubmed publisher
Korge S, Maier B, Brüning F, Ehrhardt L, Korte T, Mann M, et al. The non-classical nuclear import carrier Transportin 1 modulates circadian rhythms through its effect on PER1 nuclear localization. PLoS Genet. 2018;14:e1007189 pubmed publisher
Guo B, Huang X, Lee M, Lee S, Broxmeyer H. Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis. Nat Med. 2018;24:360-367 pubmed publisher
Wible R, Tran Q, Fathima S, Sutter C, Kensler T, Sutter T. Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo. Mol Pharmacol. 2018;93:297-308 pubmed publisher
Lyraki R, Lokaj M, Soares D, Little A, Vermeren M, Marsh J, et al. Characterization of a novel RP2-OSTF1 interaction and its implication for actin remodelling. J Cell Sci. 2018;131: pubmed publisher
Van Boxtel A, Economou A, Heliot C, Hill C. Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages. Dev Cell. 2018;44:179-191.e5 pubmed publisher
Lee S, Bazick H, Chittoor Vinod V, Al Salihi M, Xia G, Notterpek L. Elevated Peripheral Myelin Protein 22, Reduced Mitotic Potential, and Proteasome Impairment in Dermal Fibroblasts from Charcot-Marie-Tooth Disease Type 1A Patients. Am J Pathol. 2018;188:728-738 pubmed publisher
Huang X, Li X, Situ M, Huang L, Wang J, He T, et al. Entinostat reverses cisplatin resistance in esophageal squamous cell carcinoma via down-regulation of multidrug resistance gene 1. Cancer Lett. 2018;414:294-300 pubmed publisher
Li Z, Levine K, Bahreini A, Wang P, Chu D, Park B, et al. Upregulation of IRS1 Enhances IGF1 Response in Y537S and D538G ESR1 Mutant Breast Cancer Cells. Endocrinology. 2018;159:285-296 pubmed publisher
Chirumamilla C, Palagani A, Kamaraj B, Declerck K, Verbeek M, Oksana R, et al. Selective Glucocorticoid Receptor Properties of GSK866 Analogs with Cysteine Reactive Warheads. Front Immunol. 2017;8:1324 pubmed publisher
Molinari F, Pin F, Gorini S, Chiandotto S, Pontecorvo L, Penna F, et al. The mitochondrial metabolic reprogramming agent trimetazidine as an 'exercise mimetic' in cachectic C26-bearing mice. J Cachexia Sarcopenia Muscle. 2017;8:954-973 pubmed publisher
Giese S, Ciminski K, Bolte H, Moreira É, Lakdawala S, Hu Z, et al. Role of influenza A virus NP acetylation on viral growth and replication. Nat Commun. 2017;8:1259 pubmed publisher
Nieke S, Yasmin N, Kakugawa K, Yokomizo T, Muroi S, Taniuchi I. Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function. BMC Dev Biol. 2017;17:14 pubmed publisher
Tsunekuni R, Hikono H, Tanikawa T, Kurata R, Nakaya T, Saito T. Recombinant Avian Paramyxovirus Serotypes 2, 6, and 10 as Vaccine Vectors for Highly Pathogenic Avian Influenza in Chickens with Antibodies Against Newcastle Disease Virus. Avian Dis. 2017;61:296-306 pubmed publisher
Newman L, Schiavon C, Turn R, Kahn R. The ARL2 GTPase regulates mitochondrial fusion from the intermembrane space. Cell Logist. 2017;7:e1340104 pubmed publisher
Jiménez Canino R, Lorenzo Díaz F, Odermatt A, Bailey M, Livingstone D, Jaisser F, et al. 11?-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation. Endocrinology. 2017;158:4047-4063 pubmed publisher
Tyagi E, Liu B, Li C, Liu T, Rutter J, Grossman D. Loss of p16INK4A stimulates aberrant mitochondrial biogenesis through a CDK4/Rb-independent pathway. Oncotarget. 2017;8:55848-55862 pubmed publisher
Lai Y, Li J, Li X, Zou C. Lipopolysaccharide modulates p300 and Sirt1 to promote PRMT1 stability via an SCFFbxl17-recognized acetyldegron. J Cell Sci. 2017;130:3578-3587 pubmed publisher
Morabito G, Giannelli S, Ordazzo G, Bido S, Castoldi V, Indrigo M, et al. AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy. Mol Ther. 2017;25:2727-2742 pubmed publisher
Lawson A, Bak D, Shannon D, Long M, Vijaykumar T, Yu R, et al. Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry. Oncotarget. 2017;8:51296-51316 pubmed publisher
Xu Q, Jitkaew S, Choksi S, Kadigamuwa C, Qu J, Choe M, et al. The cytoplasmic nuclear receptor RAR? controls RIP1 initiated cell death when cIAP activity is inhibited. Nat Commun. 2017;8:425 pubmed publisher
Kage F, Steffen A, Ellinger A, Ranftler C, Gehre C, Brakebusch C, et al. FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42. Sci Rep. 2017;7:9791 pubmed publisher
Ma S, Dielschneider R, Henson E, Xiao W, Choquette T, Blankstein A, et al. Ferroptosis and autophagy induced cell death occur independently after siramesine and lapatinib treatment in breast cancer cells. PLoS ONE. 2017;12:e0182921 pubmed publisher
Tanikawa T, Uchida Y, Saito T. Replication of a low-pathogenic avian influenza virus is enhanced by chicken ubiquitin-specific protease 18. J Gen Virol. 2017;98:2235-2247 pubmed publisher
Zhang G, Lin L, Qi D, Zhang H. The composition of a protein aggregate modulates the specificity and efficiency of its autophagic degradation. Autophagy. 2017;13:1487-1495 pubmed publisher
Gortan Cappellari G, Semolic A, Ruozi G, Vinci P, Guarnieri G, Bortolotti F, et al. Unacylated ghrelin normalizes skeletal muscle oxidative stress and prevents muscle catabolism by enhancing tissue mitophagy in experimental chronic kidney disease. FASEB J. 2017;31:5159-5171 pubmed publisher
Antony S, Jiang G, Wu Y, Meitzler J, Makhlouf H, Haines D, et al. NADPH oxidase 5 (NOX5)-induced reactive oxygen signaling modulates normoxic HIF-1? and p27Kip1 expression in malignant melanoma and other human tumors. Mol Carcinog. 2017;56:2643-2662 pubmed publisher
Freeman R, Stephanopoulos N, Alvarez Z, Lewis J, Sur S, Serrano C, et al. Instructing cells with programmable peptide DNA hybrids. Nat Commun. 2017;8:15982 pubmed publisher
Testoni G, Duran J, García Rocha M, Vilaplana F, Serrano A, Sebastián D, et al. Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment. Cell Metab. 2017;26:256-266.e4 pubmed publisher
Geng Z, Wei L, Zhang C, Yan X. Astragalus polysaccharide, a component of traditional Chinese medicine, inhibits muscle cell atrophy (cachexia) in an in vivo and in vitro rat model of chronic renal failure by activating the ubiquitin-proteasome pathway. Exp Ther Med. 2017;14:91-96 pubmed publisher
Cartier Michaud A, Bailly A, Betzi S, Shi X, Lissitzky J, Zarubica A, et al. Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis. PLoS Genet. 2017;13:e1006803 pubmed publisher
Hou S, Kumar A, Xu Z, Airo A, Stryapunina I, Wong C, et al. Zika Virus Hijacks Stress Granule Proteins and Modulates the Host Stress Response. J Virol. 2017;91: pubmed publisher
Feng Z, Caballe A, Wainman A, Johnson S, Haensele A, Cottee M, et al. Structural Basis for Mitotic Centrosome Assembly in Flies. Cell. 2017;169:1078-1089.e13 pubmed publisher
Sarkar S, Ghosh A, Banerjee S, Maity G, Das A, Larson M, et al. CCN5/WISP-2 restores ER-∝ in normal and neoplastic breast cells and sensitizes triple negative breast cancer cells to tamoxifen. Oncogenesis. 2017;6:e340 pubmed publisher
Ma Y, Han X, Quintana Bustamante O, Bessa de Castro R, Zhang K, Zhang P, et al. Highly efficient genome editing of human hematopoietic stem cells via a nano-silicon-blade delivery approach. Integr Biol (Camb). 2017;9:548-554 pubmed publisher
Liu H, Antony S, Roy K, Juhasz A, Wu Y, Lu J, et al. Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells. Oncotarget. 2017;8:38113-38135 pubmed publisher
Kolb T, Kraxner J, Skodzek K, Haug M, Crawford D, Maaß K, et al. Optomechanical measurement of the role of lamins in whole cell deformability. J Biophotonics. 2017;10:1657-1664 pubmed publisher
Jelinek M, Kabelova A, Srámek J, Seitz J, Ojima I, Kovar J. Differing Mechanisms of Death Induction by Fluorinated Taxane SB-T-12854 in Breast Cancer Cells. Anticancer Res. 2017;37:1581-1590 pubmed
Dimchev G, Steffen A, Kage F, Dimchev V, Pernier J, Carlier M, et al. Efficiency of lamellipodia protrusion is determined by the extent of cytosolic actin assembly. Mol Biol Cell. 2017;28:1311-1325 pubmed publisher
Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed publisher
Bikkavilli R, Zerayesus S, Van Scoyk M, Wilson L, Wu P, Baskaran A, et al. K-homology splicing regulatory protein (KSRP) promotes post-transcriptional destabilization of Spry4 transcripts in non-small cell lung cancer. J Biol Chem. 2017;292:7423-7434 pubmed publisher
Guo B, Huang X, Cooper S, Broxmeyer H. Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment. Nat Med. 2017;23:424-428 pubmed publisher
Riddick G, Kotliarova S, Rodriguez V, Kim H, Linkous A, Storaska A, et al. A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity. Sci Rep. 2017;7:43605 pubmed publisher
Delpeut S, Sisson G, Black K, Richardson C. Measles Virus Enters Breast and Colon Cancer Cell Lines through a PVRL4-Mediated Macropinocytosis Pathway. J Virol. 2017;91: pubmed publisher
Labernadie A, Kato T, Brugués A, Serra Picamal X, Derzsi S, Arwert E, et al. A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion. Nat Cell Biol. 2017;19:224-237 pubmed publisher
Bellanger A, Donini C, Vendrell J, Lavaud J, Machuca Gayet I, Ruel M, et al. The critical role of the ZNF217 oncogene in promoting breast cancer metastasis to the bone. J Pathol. 2017;242:73-89 pubmed publisher
Wang H, Guo H, Su J, Rui Y, Zheng W, Gao W, et al. Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly. J Virol. 2017;91: pubmed publisher
Francis J, Newman L, Cunningham L, Kahn R. A Trimer Consisting of the Tubulin-specific Chaperone D (TBCD), Regulatory GTPase ARL2, and β-Tubulin Is Required for Maintaining the Microtubule Network. J Biol Chem. 2017;292:4336-4349 pubmed publisher
Takahashi H, Klein Z, Bhagat S, Kaufman A, Kostylev M, Ikezu T, et al. Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network. Acta Neuropathol. 2017;133:785-807 pubmed publisher
Sun M, Hou L, Tang Y, Liu Y, Wang S, Wang J, et al. Pseudorabies virus infection inhibits autophagy in permissive cells in vitro. Sci Rep. 2017;7:39964 pubmed publisher
Wang S, Lai K, Li C, Chiang C, Yu G, Sakamoto N, et al. The Paradoxical Effects of Different Hepatitis C Viral Loads on Host DNA Damage and Repair Abilities. PLoS ONE. 2017;12:e0164281 pubmed publisher
Zangari J, Ilie M, Rouaud F, Signetti L, Ohanna M, Didier R, et al. Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition. Nucleic Acids Res. 2017;45:4131-4141 pubmed publisher
Quinn S, Graves S, Dains McGahee C, Friedman E, Hassan H, Witkowski P, et al. Adenylyl cyclase 3/adenylyl cyclase-associated protein 1 (CAP1) complex mediates the anti-migratory effect of forskolin in pancreatic cancer cells. Mol Carcinog. 2017;56:1344-1360 pubmed publisher
Rubio A, Luoni M, Giannelli S, Radice I, Iannielli A, Cancellieri C, et al. Rapid and efficient CRISPR/Cas9 gene inactivation in human neurons during human pluripotent stem cell differentiation and direct reprogramming. Sci Rep. 2016;6:37540 pubmed publisher
Jiang L, Boufersaoui A, Yang C, Ko B, Rakheja D, Guevara G, et al. Quantitative metabolic flux analysis reveals an unconventional pathway of fatty acid synthesis in cancer cells deficient for the mitochondrial citrate transport protein. Metab Eng. 2017;43:198-207 pubmed publisher
Hollis F, Sevelinges Y, Grosse J, Zanoletti O, Sandi C. Involvement of CRFR1 in the Basolateral Amygdala in the Immediate Fear Extinction Deficit. Eneuro. 2016;3: pubmed
Cliburn R, Dunn A, Stout K, Hoffman C, Lohr K, Bernstein A, et al. Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain. J Chem Neuroanat. 2017;83-84:82-90 pubmed publisher
Kumar A, Hou S, Airo A, Limonta D, Mancinelli V, Branton W, et al. Zika virus inhibits type-I interferon production and downstream signaling. EMBO Rep. 2016;17:1766-1775 pubmed
Gouzil J, Fablet A, Lara E, Caignard G, Cochet M, Kundlacz C, et al. Nonstructural Protein NSs of Schmallenberg Virus Is Targeted to the Nucleolus and Induces Nucleolar Disorganization. J Virol. 2017;91: pubmed publisher
Murai J, Feng Y, Yu G, Ru Y, Tang S, Shen Y, et al. Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition. Oncotarget. 2016;7:76534-76550 pubmed publisher
Ou Y, Wang S, Li D, Chu B, Gu W. Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses. Proc Natl Acad Sci U S A. 2016;113:E6806-E6812 pubmed
Kruziki M, Case B, Chan J, Zudock E, Woldring D, Yee D, et al. 64Cu-Labeled Gp2 Domain for PET Imaging of Epidermal Growth Factor Receptor. Mol Pharm. 2016;13:3747-3755 pubmed
Coughlan K, Halang L, Woods I, Prehn J. A high-fat jelly diet restores bioenergetic balance and extends lifespan in the presence of motor dysfunction and lumbar spinal cord motor neuron loss in TDP-43A315T mutant C57BL6/J mice. Dis Model Mech. 2016;9:1029-37 pubmed publisher
Cai Z, Zhang A, Choksi S, Li W, Li T, Zhang X, et al. Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration. Cell Res. 2016;26:886-900 pubmed publisher
Ma S, Henson E, Chen Y, Gibson S. Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells. Cell Death Dis. 2016;7:e2307 pubmed publisher
Wei W, Guo H, Ma M, Markham R, Yu X. Accumulation of MxB/Mx2-resistant HIV-1 Capsid Variants During Expansion of the HIV-1 Epidemic in Human Populations. EBioMedicine. 2016;8:230-236 pubmed publisher
Whiting J, Ogier L, Forbush K, Bucko P, Gopalan J, Seternes O, et al. AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption. Proc Natl Acad Sci U S A. 2016;113:E4328-37 pubmed publisher
Li N, Richard S. Sam68 functions as a transcriptional coactivator of the p53 tumor suppressor. Nucleic Acids Res. 2016;44:8726-8741 pubmed
Madureira P, Bharadwaj A, Bydoun M, Garant K, O Connell P, Lee P, et al. Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10. Oncotarget. 2016;7:47720-47737 pubmed publisher
Werden S, Sphyris N, Sarkar T, Paranjape A, LaBaff A, Taube J, et al. Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth. Oncogene. 2016;35:5977-5988 pubmed publisher
Du M, Zhang L, Scorsone K, Woodfield S, Zage P. Nifurtimox Is Effective Against Neural Tumor Cells and Is Synergistic with Buthionine Sulfoximine. Sci Rep. 2016;6:27458 pubmed publisher
Kinsella S, König H, Prehn J. Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. Eneuro. 2016;3: pubmed publisher
Chen Y, Henson E, Xiao W, Huang D, McMillan Ward E, Israels S, et al. Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia. Autophagy. 2016;12:1029-46 pubmed publisher
Hinton A, He Y, Xia Y, Xu P, Yang Y, Saito K, et al. Estrogen Receptor-? in the Medial Amygdala Prevents Stress-Induced Elevations in Blood Pressure in Females. Hypertension. 2016;67:1321-30 pubmed publisher
Lassalle S, Zangari J, Popa A, Ilie M, Hofman V, Long E, et al. MicroRNA-375/SEC23A as biomarkers of the in vitro efficacy of vandetanib. Oncotarget. 2016;7:30461-78 pubmed publisher
Nishitani A, Tanaka M, Shimizu S, Kunisawa N, Yokoe M, Yoshida Y, et al. Involvement of aspartoacylase in tremor expression in rats. Exp Anim. 2016;65:293-301 pubmed publisher
Francis K, Ton A, Xin Y, O Halloran P, Wassif C, Malik N, et al. Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes. Nat Med. 2016;22:388-96 pubmed publisher
Lamaa A, Le Bras M, Skuli N, Britton S, Frit P, Calsou P, et al. A novel cytoprotective function for the DNA repair protein Ku in regulating p53 mRNA translation and function. EMBO Rep. 2016;17:508-18 pubmed publisher
Datan E, Roy S, Germain G, Zali N, McLean J, Golshan G, et al. Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation. Cell Death Dis. 2016;7:e2127 pubmed publisher
Costagliola A, Wojcik S, Pagano T, De Biase D, Russo V, Iovane V, et al. Age-Related Changes in Skeletal Muscle of Cattle. Vet Pathol. 2016;53:436-46 pubmed publisher
Heemskerk N, Asimuddin M, Oort C, van Rijssel J, van Buul J. Annexin A2 Limits Neutrophil Transendothelial Migration by Organizing the Spatial Distribution of ICAM-1. J Immunol. 2016;196:2767-78 pubmed publisher
Herrera R, Kiontke K, Fitch D. Makorin ortholog LEP-2 regulates LIN-28 stability to promote the juvenile-to-adult transition in Caenorhabditis elegans. Development. 2016;143:799-809 pubmed publisher
Henssen A, Althoff K, Odersky A, Beckers A, Koche R, Speleman F, et al. Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition. Clin Cancer Res. 2016;22:2470-81 pubmed publisher
Yin D, Liang X, Zhao L, Zhang H, Sun Q, Wang P, et al. Jinmaitong decreases sciatic nerve DNA oxidative damage and apoptosis in a streptozotocin-induced diabetic rat model. Exp Ther Med. 2015;10:778-786 pubmed
Yao W, Hu Q, Ma Y, Xiong W, Wu T, Cao J, et al. Human adipose-derived mesenchymal stem cells repair cisplatin-induced acute kidney injury through antiapoptotic pathways. Exp Ther Med. 2015;10:468-476 pubmed
Marangoni D, Vijayasarathy C, Bush R, Wei L, Wen R, Sieving P. Intravitreal Ciliary Neurotrophic Factor Transiently Improves Cone-Mediated Function in a CNGB3-/- Mouse Model of Achromatopsia. Invest Ophthalmol Vis Sci. 2015;56:6810-22 pubmed publisher
Liang Z, Ye T, Zhou X, Lai K, Fu A, Ip N. Cdk5 Regulates Activity-Dependent Gene Expression and Dendrite Development. J Neurosci. 2015;35:15127-34 pubmed publisher
Young G, Radhakrishnan V, Centuori S, Gomes C, Martinez J. Comparative analysis of 14-3-3 isoform expression and epigenetic alterations in colorectal cancer. BMC Cancer. 2015;15:826 pubmed publisher
Davies C, Hogarth L, MacKenzie K, Hall A, Lock R. p21(WAF1) modulates drug-induced apoptosis and cell cycle arrest in B-cell precursor acute lymphoblastic leukemia. Cell Cycle. 2015;14:3602-12 pubmed publisher
Ellis P, Burbridge S, Soubes S, Ohyama K, Ben Haim N, Chen C, et al. ProNodal acts via FGFR3 to govern duration of Shh expression in the prechordal mesoderm. Development. 2015;142:3821-32 pubmed publisher
Orr A, Vargas L, Turk C, Baaten J, Matzen J, Dardov V, et al. Suppressors of superoxide production from mitochondrial complex III. Nat Chem Biol. 2015;11:834-6 pubmed publisher
Takeuchi H, Mmeje C, Jinesh G, Taoka R, Kamat A. Sequential gemcitabine and tamoxifen treatment enhances apoptosis and blocks transformation in bladder cancer cells. Oncol Rep. 2015;34:2738-44 pubmed publisher
Fullerton P, Creighton C, Matzuk M. Insights Into SMAD4 Loss in Pancreatic Cancer From Inducible Restoration of TGF-β Signaling. Mol Endocrinol. 2015;29:1440-53 pubmed publisher
Korge S, Grudziecki A, Kramer A. Highly Efficient Genome Editing via CRISPR/Cas9 to Create Clock Gene Knockout Cells. J Biol Rhythms. 2015;30:389-95 pubmed publisher
Zidek L, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, et al. Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice. EMBO Rep. 2015;16:1022-36 pubmed publisher
Gottschalk E, Meneses P. A Dual Role for the Nonreceptor Tyrosine Kinase Pyk2 during the Intracellular Trafficking of Human Papillomavirus 16. J Virol. 2015;89:9103-14 pubmed publisher
Dey S, Sayers C, Verginadis I, Lehman S, Cheng Y, Cerniglia G, et al. ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis. J Clin Invest. 2015;125:2592-608 pubmed publisher
Glaser G, Weroha S, Becker M, Hou X, Enderica Gonzalez S, Harrington S, et al. Conventional chemotherapy and oncogenic pathway targeting in ovarian carcinosarcoma using a patient-derived tumorgraft. PLoS ONE. 2015;10:e0126867 pubmed publisher
Agarwal S, Agarwal S, Biancucci M, Satchell K. Induced autoprocessing of the cytopathic Makes caterpillars floppy-like effector domain of the Vibrio vulnificus MARTX toxin. Cell Microbiol. 2015;17:1494-509 pubmed publisher
Li Chew C, Lunardi A, Gulluni F, Ruan D, Chen M, Salmena L, et al. In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes. Cancer Discov. 2015;5:740-51 pubmed publisher
Jiang L, Kon N, Li T, Wang S, Su T, Hibshoosh H, et al. Ferroptosis as a p53-mediated activity during tumour suppression. Nature. 2015;520:57-62 pubmed publisher
Liu Y, Han X, Gao B. Knockdown of S100A11 expression suppresses ovarian cancer cell growth and invasion. Exp Ther Med. 2015;9:1460-1464 pubmed
Watanabe T, Sekine S, Naguro I, Sekine Y, Ichijo H. Apoptosis Signal-regulating Kinase 1 (ASK1)-p38 Pathway-dependent Cytoplasmic Translocation of the Orphan Nuclear Receptor NR4A2 Is Required for Oxidative Stress-induced Necrosis. J Biol Chem. 2015;290:10791-803 pubmed publisher
Bursomanno S, McGouran J, Kessler B, Hickson I, Liu Y. Regulation of SUMO2 target proteins by the proteasome in human cells exposed to replication stress. J Proteome Res. 2015;14:1687-99 pubmed publisher
Bikkavilli R, Avasarala S, Van Scoyk M, Arcaroli J, Brzezinski C, Zhang W, et al. Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer. Oncogene. 2015;34:5317-28 pubmed publisher
Jelínek M, Balušíková K, Schmiedlová M, Němcová Fürstová V, Šrámek J, Stančíková J, et al. The role of individual caspases in cell death induction by taxanes in breast cancer cells. Cancer Cell Int. 2015;15:8 pubmed publisher
Corkery D, Le Page C, Meunier L, Provencher D, Mes Masson A, Dellaire G. PRP4K is a HER2-regulated modifier of taxane sensitivity. Cell Cycle. 2015;14:1059-69 pubmed publisher
Zimmerman A, Harris R. In vivo and in vitro evidence that chronic activation of the hexosamine biosynthetic pathway interferes with leptin-dependent STAT3 phosphorylation. Am J Physiol Regul Integr Comp Physiol. 2015;308:R543-55 pubmed publisher
Pavlíková N, Bartoňová I, Balušíková K, Kopperová D, Halada P, Kovář J. Differentially expressed proteins in human MCF-7 breast cancer cells sensitive and resistant to paclitaxel. Exp Cell Res. 2015;333:1-10 pubmed publisher
Giordano C, Mojumdar K, Liang F, Lemaire C, Li T, Richardson J, et al. Toll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy. Hum Mol Genet. 2015;24:2147-62 pubmed publisher
Zhang F, Kumano M, Beraldi E, Fazli L, Du C, Moore S, et al. Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival. Nat Commun. 2014;5:5775 pubmed publisher
Cunningham T, Greenstein J, Loewenstern J, Degermentzidis E, Yao L. Anti-inflammatory peptide regulates the supply of heat shock protein 70 monomers: implications for aging and age-related disease. Rejuvenation Res. 2015;18:136-44 pubmed publisher
Mimouna S, Bazin M, Mograbi B, Darfeuille Michaud A, Brest P, Hofman P, et al. HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC). Autophagy. 2014;10:2333-45 pubmed publisher
Harris R, Apolzan J. Hexosamine biosynthetic pathway activity in leptin resistant sucrose-drinking rats. Physiol Behav. 2015;138:208-18 pubmed publisher
Ou Y, Wang S, Jiang L, Zheng B, Gu W. p53 Protein-mediated regulation of phosphoglycerate dehydrogenase (PHGDH) is crucial for the apoptotic response upon serine starvation. J Biol Chem. 2015;290:457-66 pubmed publisher
Yakunin E, Kisos H, Kulik W, Grigoletto J, Wanders R, Sharon R. The regulation of catalase activity by PPAR γ is affected by α-synuclein. Ann Clin Transl Neurol. 2014;1:145-59 pubmed publisher
Althoff K, Beckers A, Bell E, Nortmeyer M, Thor T, Sprüssel A, et al. A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies. Oncogene. 2015;34:3357-68 pubmed publisher
Liu T, Song T, Zhang X, Yuan H, Su L, Li W, et al. Unconventionally secreted effectors of two filamentous pathogens target plant salicylate biosynthesis. Nat Commun. 2014;5:4686 pubmed publisher
Guo B, Huang J, Wu W, Feng D, Wang X, Chen Y, et al. The nascent polypeptide-associated complex is essential for autophagic flux. Autophagy. 2014;10:1738-48 pubmed publisher
Sarkar T, Battula V, Werden S, Vijay G, Ramirez Peña E, Taube J, et al. GD3 synthase regulates epithelial-mesenchymal transition and metastasis in breast cancer. Oncogene. 2015;34:2958-67 pubmed publisher
Bailon E, Ugarte Berzal E, Amigo Jiménez I, Van den Steen P, Opdenakker G, Garcia Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed publisher
Hsieh W, Sung T, Wang H, Hsieh M. Functional evidence for the critical amino-terminal conserved domain and key amino acids of Arabidopsis 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE. Plant Physiol. 2014;166:57-69 pubmed publisher
Poirier G, Imamura N, Zanoletti O, Sandi C. Social deficits induced by peripubertal stress in rats are reversed by resveratrol. J Psychiatr Res. 2014;57:157-64 pubmed publisher
Walsh L, Roy D, Reyngold M, Giri D, Snyder A, Turcan S, et al. RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch. Oncogene. 2015;34:2189-203 pubmed publisher
Damm F, Mylonas E, Cosson A, Yoshida K, Della Valle V, Mouly E, et al. Acquired initiating mutations in early hematopoietic cells of CLL patients. Cancer Discov. 2014;4:1088-101 pubmed publisher
Wei H, Jin J. A dominantly negative mutation in cardiac troponin I at the interface with troponin T causes early remodeling in ventricular cardiomyocytes. Am J Physiol Cell Physiol. 2014;307:C338-48 pubmed publisher
Pavlikova N, Bartonova I, Dincakova L, Halada P, Kovar J. Differentially expressed proteins in human breast cancer cells sensitive and resistant to paclitaxel. Int J Oncol. 2014;45:822-30 pubmed publisher
White E, Schlackow M, Kamieniarz Gdula K, Proudfoot N, Gullerova M. Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA. Nat Struct Mol Biol. 2014;21:552-9 pubmed publisher
Maitra R, Seetharam R, Tesfa L, Augustine T, Klampfer L, Coffey M, et al. Oncolytic reovirus preferentially induces apoptosis in KRAS mutant colorectal cancer cells, and synergizes with irinotecan. Oncotarget. 2014;5:2807-19 pubmed
Cortelazzo A, De Felice C, Pecorelli A, Belmonte G, Signorini C, Leoncini S, et al. Beta-actin deficiency with oxidative posttranslational modifications in Rett syndrome erythrocytes: insights into an altered cytoskeletal organization. PLoS ONE. 2014;9:e93181 pubmed publisher
Boettcher M, Lawson A, Ladenburger V, Fredebohm J, Wolf J, Hoheisel J, et al. High throughput synthetic lethality screen reveals a tumorigenic role of adenylate cyclase in fumarate hydratase-deficient cancer cells. BMC Genomics. 2014;15:158 pubmed publisher
Liu Z, Vong Q, Liu C, Zheng Y. Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells. Mol Biol Cell. 2014;25:841-51 pubmed publisher
Honarpour N, Rose C, Brumbaugh J, Anderson J, Graham R, Sweredoski M, et al. F-box protein FBXL16 binds PP2A-B55? and regulates differentiation of embryonic stem cells along the FLK1+ lineage. Mol Cell Proteomics. 2014;13:780-91 pubmed publisher
Han X, Liang W, Hua D, Zhou X, Du J, Evans S, et al. Evolutionarily conserved requirement for core binding factor beta in the assembly of the human immunodeficiency virus/simian immunodeficiency virus Vif-cullin 5-RING E3 ubiquitin ligase. J Virol. 2014;88:3320-8 pubmed publisher
Takasaka N, Araya J, Hara H, Ito S, Kobayashi K, Kurita Y, et al. Autophagy induction by SIRT6 through attenuation of insulin-like growth factor signaling is involved in the regulation of human bronchial epithelial cell senescence. J Immunol. 2014;192:958-68 pubmed publisher
Alagoz M, Wells O, El Khamisy S. TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy. Nucleic Acids Res. 2014;42:3089-103 pubmed publisher
Rigbolt K, Zarei M, Sprenger A, Becker A, Diedrich B, Huang X, et al. Characterization of early autophagy signaling by quantitative phosphoproteomics. Autophagy. 2014;10:356-71 pubmed publisher
Eletr Z, Yin L, Wilkinson K. BAP1 is phosphorylated at serine 592 in S-phase following DNA damage. FEBS Lett. 2013;587:3906-11 pubmed publisher
Kuo D, Labelle Dumais C, Mao M, Jeanne M, Kauffman W, Allen J, et al. Allelic heterogeneity contributes to variability in ocular dysgenesis, myopathy and brain malformations caused by Col4a1 and Col4a2 mutations. Hum Mol Genet. 2014;23:1709-22 pubmed publisher
Wei W, Guo H, Gao Q, Markham R, Yu X. Variation of two primate lineage-specific residues in human SAMHD1 confers resistance to N terminus-targeted SIV Vpx proteins. J Virol. 2014;88:583-91 pubmed publisher
Gilbert M, Soderstrom K. Novel song-stimulated dendritic spine formation and Arc/Arg3.1 expression in zebra finch auditory telencephalon are disrupted by cannabinoid agonism. Brain Res. 2013;1541:9-21 pubmed publisher
Tamplenizza M, Lenardi C, Maffioli E, Nonnis S, Negri A, Forti S, et al. Nitric oxide synthase mediates PC12 differentiation induced by the surface topography of nanostructured TiO2. J Nanobiotechnology. 2013;11:35 pubmed publisher
Reichert S, Randall R, Hill C. A BMP regulatory network controls ectodermal cell fate decisions at the neural plate border. Development. 2013;140:4435-44 pubmed publisher
de Kreuk B, Schaefer A, Anthony E, Tol S, Fernandez Borja M, Geerts D, et al. The human minor histocompatibility antigen 1 is a RhoGAP. PLoS ONE. 2013;8:e73962 pubmed publisher
Pierini R, Perret M, Djebali S, Juruj C, Michallet M, Forster I, et al. ASC controls IFN-? levels in an IL-18-dependent manner in caspase-1-deficient mice infected with Francisella novicida. J Immunol. 2013;191:3847-57 pubmed publisher
Nobbio L, Visigalli D, Mannino E, Fiorese F, Kassack M, Sturla L, et al. The diadenosine homodinucleotide P18 improves in vitro myelination in experimental Charcot-Marie-Tooth type 1A. J Cell Biochem. 2014;115:161-7 pubmed publisher
Vyas S, Chesarone Cataldo M, Todorova T, Huang Y, Chang P. A systematic analysis of the PARP protein family identifies new functions critical for cell physiology. Nat Commun. 2013;4:2240 pubmed publisher
Cooke G, Govender P, Watson C, Armstrong M, O Dwyer D, Keane M, et al. Sarcoidosis, alveolar ?-actin and pulmonary fibrosis. QJM. 2013;106:897-902 pubmed publisher
Reiner D, Yu S, Shen H, He Y, Bae E, Wang Y. 9-Cis retinoic acid protects against methamphetamine-induced neurotoxicity in nigrostriatal dopamine neurons. Neurotox Res. 2014;25:248-61 pubmed publisher
Feng Y, Singleton D, Guo C, Gardner A, Pakala S, Kumar R, et al. DNA homologous recombination factor SFR1 physically and functionally interacts with estrogen receptor alpha. PLoS ONE. 2013;8:e68075 pubmed publisher
Guo H, Wei W, Wei Z, Liu X, Evans S, Yang W, et al. Identification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradation. PLoS ONE. 2013;8:e66201 pubmed publisher
Han X, Liu D, Zhang Y, Li Y, Lu W, Chen J, et al. Akt regulates TPP1 homodimerization and telomere protection. Aging Cell. 2013;12:1091-9 pubmed publisher
Antony S, Wu Y, Hewitt S, Anver M, Butcher D, Jiang G, et al. Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody. Free Radic Biol Med. 2013;65:497-508 pubmed publisher
Patel H, Zich J, Serrels B, Rickman C, Hardwick K, Frame M, et al. Kindlin-1 regulates mitotic spindle formation by interacting with integrins and Plk-1. Nat Commun. 2013;4:2056 pubmed publisher
Björkblom B, Adilbayeva A, Maple Grødem J, Piston D, Okvist M, Xu X, et al. Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity. J Biol Chem. 2013;288:22809-20 pubmed publisher
Jelinek M, Balusikova K, Kopperová D, Němcová Fürstová V, Srámek J, Fidlerova J, et al. Caspase-2 is involved in cell death induction by taxanes in breast cancer cells. Cancer Cell Int. 2013;13:42 pubmed publisher
Simpson K, Cawthorne C, Zhou C, Hodgkinson C, Walker M, Trapani F, et al. A caspase-3 'death-switch' in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers. Cell Death Dis. 2013;4:e613 pubmed publisher
Sharma P, Thakran S, Deng X, Elam M, Park E. Nuclear corepressors mediate the repression of phospholipase A2 group IIa gene transcription by thyroid hormone. J Biol Chem. 2013;288:16321-33 pubmed publisher
Pe er T, Lahmi R, Sharaby Y, Chorni E, Noach M, Vecsler M, et al. Gas2l3, a novel constriction site-associated protein whose regulation is mediated by the APC/C Cdh1 complex. PLoS ONE. 2013;8:e57532 pubmed publisher
Wu L, Lee S, Zhou B, Nguyen U, Muir T, Tan S, et al. ASH2L regulates ubiquitylation signaling to MLL: trans-regulation of H3 K4 methylation in higher eukaryotes. Mol Cell. 2013;49:1108-20 pubmed publisher
Wu Y, Antony S, Hewitt S, Jiang G, Yang S, Meitzler J, et al. Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody. Int J Oncol. 2013;42:1229-38 pubmed publisher
Yao Q, Shin M, Jun J, Hernandez K, Aggarwal N, Mock J, et al. Effect of chronic intermittent hypoxia on triglyceride uptake in different tissues. J Lipid Res. 2013;54:1058-65 pubmed publisher
Shi G, Sohn K, Li Z, Choi D, Park Y, Kim J, et al. Expression and functional role of Sox9 in human epidermal keratinocytes. PLoS ONE. 2013;8:e54355 pubmed publisher
Wu Y, Lu J, Antony S, Juhasz A, Liu H, Jiang G, et al. Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-γ and lipopolysaccharide in human pancreatic cancer cell lines. J Immunol. 2013;190:1859-72 pubmed publisher
Hebert A, DUBOFF B, Casaletto J, Gladden A, McClatchey A. Merlin/ERM proteins establish cortical asymmetry and centrosome position. Genes Dev. 2012;26:2709-23 pubmed publisher
Vernier S, Chiu A, Schober J, Weber T, Nguyen P, LUER M, et al. ?-cell metabolic alterations under chronic nutrient overload in rat and human islets. Islets. 2012;4:379-92 pubmed publisher
Madureira P, Hill R, Lee P, Waisman D. Genotoxic agents promote the nuclear accumulation of annexin A2: role of annexin A2 in mitigating DNA damage. PLoS ONE. 2012;7:e50591 pubmed publisher
Hou S, Lei L, Yang Z, Qi M, Liu Q, Zhong G. Chlamydia trachomatis outer membrane complex protein B (OmcB) is processed by the protease CPAF. J Bacteriol. 2013;195:951-7 pubmed publisher
Thakran S, Sharma P, Attia R, Hori R, Deng X, Elam M, et al. Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone. J Biol Chem. 2013;288:807-18 pubmed publisher
Liu S, Leask A. Integrin β1 is required for dermal homeostasis. J Invest Dermatol. 2013;133:899-906 pubmed publisher
Jenkins N, Jung J, Liu T, Wilde M, Holmen S, Grossman D. Familial melanoma-associated mutations in p16 uncouple its tumor-suppressor functions. J Invest Dermatol. 2013;133:1043-51 pubmed publisher
Tervaniemi M, Siitonen H, Söderhäll C, Minhas G, Vuola J, Tiala I, et al. Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization. PLoS ONE. 2012;7:e49920 pubmed publisher
Huang H, Kang R, Wang J, Luo G, Yang W, Zhao Z. Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy. Autophagy. 2013;9:175-95 pubmed publisher
Hau A, Ceppi P, Peter M. CD95 is part of a let-7/p53/miR-34 regulatory network. PLoS ONE. 2012;7:e49636 pubmed publisher
de Kreuk B, Anthony E, Geerts D, Hordijk P. The F-BAR protein PACSIN2 regulates epidermal growth factor receptor internalization. J Biol Chem. 2012;287:43438-53 pubmed publisher
Murai J, Huang S, Das B, Renaud A, Zhang Y, Doroshow J, et al. Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors. Cancer Res. 2012;72:5588-99 pubmed publisher
Cantara S, Soscia D, Sequeira S, Jean Gilles R, Castracane J, Larsen M. Selective functionalization of nanofiber scaffolds to regulate salivary gland epithelial cell proliferation and polarity. Biomaterials. 2012;33:8372-82 pubmed publisher
Douarre C, Sourbier C, Dalla Rosa I, Brata Das B, Redon C, Zhang H, et al. Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism. PLoS ONE. 2012;7:e41094 pubmed publisher
Nelson C, Gorsuch R, Bailey T, Ackerman K, Kassen S, Hyde D. Stat3 defines three populations of Müller glia and is required for initiating maximal müller glia proliferation in the regenerating zebrafish retina. J Comp Neurol. 2012;520:4294-311 pubmed publisher
Vara D, Campanella M, Pula G. The novel NOX inhibitor 2-acetylphenothiazine impairs collagen-dependent thrombus formation in a GPVI-dependent manner. Br J Pharmacol. 2013;168:212-24 pubmed publisher
Miao Y, Dong L, Chen J, Hu X, Yang X, Wang Z. Involvement of calpain/p35-p25/Cdk5/NMDAR signaling pathway in glutamate-induced neurotoxicity in cultured rat retinal neurons. PLoS ONE. 2012;7:e42318 pubmed publisher
Zhen A, Du J, Zhou X, Xiong Y, Yu X. Reduced APOBEC3H variant anti-viral activities are associated with altered RNA binding activities. PLoS ONE. 2012;7:e38771 pubmed publisher
Jerez A, Clemente M, Makishima H, Koskela H, LeBlanc F, Peng Ng K, et al. STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia. Blood. 2012;120:3048-57 pubmed publisher
Wei W, Guo H, Han X, Liu X, Zhou X, Zhang W, et al. A novel DCAF1-binding motif required for Vpx-mediated degradation of nuclear SAMHD1 and Vpr-induced G2 arrest. Cell Microbiol. 2012;14:1745-56 pubmed publisher
Halloran J, Hussong S, Burbank R, Podlutskaya N, Fischer K, Sloane L, et al. Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice. Neuroscience. 2012;223:102-13 pubmed publisher
Sun M, Huang L, Wang R, Yu Y, Li C, Li P, et al. Porcine reproductive and respiratory syndrome virus induces autophagy to promote virus replication. Autophagy. 2012;8:1434-47 pubmed publisher
Ortega I, Villanueva J, Wong D, Cress A, Sokalska A, Stanley S, et al. Resveratrol reduces steroidogenesis in rat ovarian theca-interstitial cells: the role of inhibition of Akt/PKB signaling pathway. Endocrinology. 2012;153:4019-29 pubmed publisher
Nande R, Di Benedetto A, Aimola P, de Carlo F, Carper M, Claudio C, et al. Targeting a newly established spontaneous feline fibrosarcoma cell line by gene transfer. PLoS ONE. 2012;7:e37743 pubmed publisher
Jun J, Shin M, Yao Q, Bevans Fonti S, Poole J, Drager L, et al. Acute hypoxia induces hypertriglyceridemia by decreasing plasma triglyceride clearance in mice. Am J Physiol Endocrinol Metab. 2012;303:E377-88 pubmed publisher
Noberini R, Rubio de la Torre E, Pasquale E. Profiling Eph receptor expression in cells and tissues: a targeted mass spectrometry approach. Cell Adh Migr. 2012;6:102-12 pubmed publisher
Chung E, Psathas J, Yu D, Li Y, Weiss M, Thomas Tikhonenko A. CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesis. J Clin Invest. 2012;122:2257-66 pubmed publisher
Chen B, Zhong L, Roush S, Pentassuglia L, Peng X, Samaras S, et al. Disruption of a GATA4/Ankrd1 signaling axis in cardiomyocytes leads to sarcomere disarray: implications for anthracycline cardiomyopathy. PLoS ONE. 2012;7:e35743 pubmed publisher
Muñoz M, Martín Montañez E. Ferric carboxymaltose for the treatment of iron-deficiency anemia. [corrected]. Expert Opin Pharmacother. 2012;13:907-21 pubmed publisher
Olsen B, Wang S, Svenstrup T, Chen B, Guerra B. Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage. BMC Mol Biol. 2012;13:7 pubmed publisher
Mognol G, de Araujo Souza P, Robbs B, Teixeira L, Viola J. Transcriptional regulation of the c-Myc promoter by NFAT1 involves negative and positive NFAT-responsive elements. Cell Cycle. 2012;11:1014-28 pubmed publisher
Zhang Y, Morgan M, Chen K, Choksi S, Liu Z. Induction of autophagy is essential for monocyte-macrophage differentiation. Blood. 2012;119:2895-905 pubmed publisher
Madureira P, Hill R, Miller V, Giacomantonio C, Lee P, Waisman D. Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis. Oncotarget. 2011;2:1075-93 pubmed
Cardinale A, Racaniello M, Saladini S, De Chiara G, Mollinari C, De Stefano M, et al. Sublethal doses of ?-amyloid peptide abrogate DNA-dependent protein kinase activity. J Biol Chem. 2012;287:2618-31 pubmed publisher
Di Cara B, Maggio R, Aloisi G, Rivet J, Lundius E, Yoshitake T, et al. Genetic deletion of trace amine 1 receptors reveals their role in auto-inhibiting the actions of ecstasy (MDMA). J Neurosci. 2011;31:16928-40 pubmed publisher
Guo W, Murthy A, Zhang L, Johnson E, Schaller E, Allan A, et al. Inhibition of GSK3β improves hippocampus-dependent learning and rescues neurogenesis in a mouse model of fragile X syndrome. Hum Mol Genet. 2012;21:681-91 pubmed publisher
Schulz N, Himmelbauer H, Rath M, van Weeghel M, Houten S, Kulik W, et al. Role of medium- and short-chain L-3-hydroxyacyl-CoA dehydrogenase in the regulation of body weight and thermogenesis. Endocrinology. 2011;152:4641-51 pubmed publisher
Tyrberg B, Miles P, Azizian K, Denzel M, Nieves M, Monosov E, et al. T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion. Islets. 2011;3:327-37 pubmed publisher
Dostalikova Cimburova M, Kratka K, Balusikova K, Chmelikova J, Hejda V, Hnaníček J, et al. Duodenal expression of iron transport molecules in patients with hereditary hemochromatosis or iron deficiency. J Cell Mol Med. 2012;16:1816-26 pubmed publisher
Lamande S, Yuan Y, Gresshoff I, Rowley L, Belluoccio D, Kaluarachchi K, et al. Mutations in TRPV4 cause an inherited arthropathy of hands and feet. Nat Genet. 2011;43:1142-6 pubmed publisher
Qiu W, Chen L, Kassem M. Activation of non-canonical Wnt/JNK pathway by Wnt3a is associated with differentiation fate determination of human bone marrow stromal (mesenchymal) stem cells. Biochem Biophys Res Commun. 2011;413:98-104 pubmed publisher
Béliveau F, Brulé C, Desilets A, Zimmerman B, Laporte S, Lavoie C, et al. Essential role of endocytosis of the type II transmembrane serine protease TMPRSS6 in regulating its functionality. J Biol Chem. 2011;286:29035-43 pubmed publisher
de Kreuk B, Nethe M, Fernandez Borja M, Anthony E, Hensbergen P, Deelder A, et al. The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration. J Cell Sci. 2011;124:2375-88 pubmed publisher
Zhang M, Dai C, Zhu H, Chen S, Wu Y, Li Q, et al. Cyclophilin A promotes human hepatocellular carcinoma cell metastasis via regulation of MMP3 and MMP9. Mol Cell Biochem. 2011;357:387-95 pubmed publisher
Merrill M, Edwards N, Lonser R. Notch receptor and effector expression in von Hippel-Lindau disease-associated central nervous system hemangioblastomas. J Neurosurg. 2011;115:512-7 pubmed publisher
Theriault J, Palmer H, Pittman D. Inhibition of the Unfolded Protein Response by metformin in renal proximal tubular epithelial cells. Biochem Biophys Res Commun. 2011;409:500-5 pubmed publisher
Broholm C, Laye M, Brandt C, Vadalasetty R, Pilegaard H, Pedersen B, et al. LIF is a contraction-induced myokine stimulating human myocyte proliferation. J Appl Physiol (1985). 2011;111:251-9 pubmed publisher
Drager L, Li J, Shin M, Reinke C, Aggarwal N, Jun J, et al. Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea. Eur Heart J. 2012;33:783-90 pubmed publisher
Huang X, Zhang H, Zhang H. The zinc-finger protein SEA-2 regulates larval developmental timing and adult lifespan in C. elegans. Development. 2011;138:2059-68 pubmed publisher
Perez Nadales E, Di Pietro A. The membrane mucin Msb2 regulates invasive growth and plant infection in Fusarium oxysporum. Plant Cell. 2011;23:1171-85 pubmed publisher
Misselwitz B, Dilling S, Vonaesch P, Sacher R, Snijder B, Schlumberger M, et al. RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42. Mol Syst Biol. 2011;7:474 pubmed publisher
Foxler D, James V, Shelton S, Vallim T, Shaw P, Sharp T. PU.1 is a major transcriptional activator of the tumour suppressor gene LIMD1. FEBS Lett. 2011;585:1089-96 pubmed publisher
Talbot K, Louneva N, Cohen J, Kazi H, Blake D, Arnold S. Synaptic dysbindin-1 reductions in schizophrenia occur in an isoform-specific manner indicating their subsynaptic location. PLoS ONE. 2011;6:e16886 pubmed publisher
Spannhoff A, Kim Y, Raynal N, Gharibyan V, Su M, Zhou Y, et al. Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees. EMBO Rep. 2011;12:238-43 pubmed publisher
Wu Y, Antony S, Juhasz A, Lu J, Ge Y, Jiang G, et al. Up-regulation and sustained activation of Stat1 are essential for interferon-gamma (IFN-gamma)-induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines. J Biol Chem. 2011;286:12245-56 pubmed publisher
Saiya Cork K, Collins R, Parkin B, Ouillette P, Kuizon E, Kujawski L, et al. A pathobiological role of the insulin receptor in chronic lymphocytic leukemia. Clin Cancer Res. 2011;17:2679-92 pubmed publisher
Clark J, Anderson K, Juvin V, Smith T, Karpe F, Wakelam M, et al. Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry. Nat Methods. 2011;8:267-72 pubmed publisher
Carkaci Salli N, Salli U, Kuntz Melcavage K, Pennock M, Ozgen H, Tekin I, et al. TPH2 in the ventral tegmental area of the male rat brain. Brain Res Bull. 2011;84:376-80 pubmed publisher
Vrouwe M, Pines A, Overmeer R, Hanada K, Mullenders L. UV-induced photolesions elicit ATR-kinase-dependent signaling in non-cycling cells through nucleotide excision repair-dependent and -independent pathways. J Cell Sci. 2011;124:435-46 pubmed publisher
Cohen J, Louneva N, Han L, Hodes G, Wilson R, Bennett D, et al. Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain. Synapse. 2011;65:763-70 pubmed publisher
Aversa A, Caprio M, Antelmi A, Armani A, Brama M, Greco E, et al. Exposure to phosphodiesterase type 5 inhibitors stimulates aromatase expression in human adipocytes in vitro. J Sex Med. 2011;8:696-704 pubmed publisher
Pol C, Muller A, Zuidwijk M, van Deel E, Kaptein E, Saba A, et al. Left-ventricular remodeling after myocardial infarction is associated with a cardiomyocyte-specific hypothyroid condition. Endocrinology. 2011;152:669-79 pubmed publisher
Nadanaka S, Kinouchi H, Taniguchi Morita K, Tamura J, Kitagawa H. Down-regulation of chondroitin 4-O-sulfotransferase-1 by Wnt signaling triggers diffusion of Wnt-3a. J Biol Chem. 2011;286:4199-208 pubmed publisher
Suon S, Zhao J, Villarreal S, Anumula N, Liu M, Carangia L, et al. Systemic treatment with liver X receptor agonists raises apolipoprotein E, cholesterol, and amyloid-? peptides in the cerebral spinal fluid of rats. Mol Neurodegener. 2010;5:44 pubmed publisher
Andersen R, Sørensen R, Ritter C, Svane I, Becker J, thor Straten P, et al. Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors. Cancer Immunol Immunother. 2011;60:227-34 pubmed publisher
Gershome C, Lin E, Kashihara H, Hove Madsen L, Tibbits G. Colocalization of voltage-gated Na+ channels with the Na+/Ca2+ exchanger in rabbit cardiomyocytes during development. Am J Physiol Heart Circ Physiol. 2011;300:H300-11 pubmed publisher
Luo H, Hallen Adams H, Scott Craig J, Walton J. Colocalization of amanitin and a candidate toxin-processing prolyl oligopeptidase in Amanita basidiocarps. Eukaryot Cell. 2010;9:1891-900 pubmed publisher
Pula G, Garonna E, Dunn W, Hirano M, Pizzorno G, Campanella M, et al. Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate. Arterioscler Thromb Vasc Biol. 2010;30:2631-8 pubmed publisher
Jenkins N, Liu T, Cassidy P, Leachman S, Boucher K, Goodson A, et al. The p16(INK4A) tumor suppressor regulates cellular oxidative stress. Oncogene. 2011;30:265-74 pubmed publisher
Vanoaica L, Darshan D, Richman L, Schümann K, Kühn L. Intestinal ferritin H is required for an accurate control of iron absorption. Cell Metab. 2010;12:273-82 pubmed publisher
Fan R, Li X, Du W, Zou X, Du R, Zhao L, et al. Adenoviral-mediated RNA interference targeting URG11 inhibits growth of human hepatocellular carcinoma. Int J Cancer. 2011;128:2980-93 pubmed publisher
Li T, Morgan M, Choksi S, Zhang Y, Kim Y, Liu Z. MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation. Nat Immunol. 2010;11:799-805 pubmed publisher
Kreisler A, Strissel P, Strick R, Neumann S, Schumacher U, Becker C. Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer. Oncogene. 2010;29:5828-38 pubmed publisher
Leach N, Roller R. Significance of host cell kinases in herpes simplex virus type 1 egress and lamin-associated protein disassembly from the nuclear lamina. Virology. 2010;406:127-37 pubmed publisher
Poliseno L, Salmena L, Riccardi L, Fornari A, Song M, Hobbs R, et al. Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal. 2010;3:ra29 pubmed publisher
Spilman P, Podlutskaya N, Hart M, Debnath J, Gorostiza O, Bredesen D, et al. Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease. PLoS ONE. 2010;5:e9979 pubmed publisher
Woods A, James C, Wang G, Dupuis H, Beier F. Control of chondrocyte gene expression by actin dynamics: a novel role of cholesterol/Ror-alpha signalling in endochondral bone growth. J Cell Mol Med. 2009;13:3497-516 pubmed publisher
Yan H, Blackburn A, McLary S, Tao L, Roberts A, Xavier E, et al. Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice. Am J Pathol. 2010;176:1421-32 pubmed publisher
Zhang Y, Soto J, Park K, Viswanath G, Kuwada S, Abel E, et al. Nuclear receptor SHP, a death receptor that targets mitochondria, induces apoptosis and inhibits tumor growth. Mol Cell Biol. 2010;30:1341-56 pubmed publisher
McConell G, Ng G, Phillips M, Ruan Z, Macaulay S, Wadley G. Central role of nitric oxide synthase in AICAR and caffeine-induced mitochondrial biogenesis in L6 myocytes. J Appl Physiol (1985). 2010;108:589-95 pubmed publisher
Lee K, Li M, Michalowski A, Zhang X, Liao H, Chen L, et al. A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells. Proc Natl Acad Sci U S A. 2010;107:69-74 pubmed publisher
Zhen A, Wang T, Zhao K, Xiong Y, Yu X. A single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity. J Virol. 2010;84:1902-11 pubmed publisher
Lei Z, Deng P, Li Y, Xu Z. Downregulation of Kv4.2 channels mediated by NR2B-containing NMDA receptors in cultured hippocampal neurons. Neuroscience. 2010;165:350-62 pubmed publisher
Zhang L, Li L, Leavesley H, Zhang X, Borowitz J, Isom G. Cyanide-induced apoptosis of dopaminergic cells is promoted by BNIP3 and Bax modulation of endoplasmic reticulum-mitochondrial Ca2+ levels. J Pharmacol Exp Ther. 2010;332:97-105 pubmed publisher
Lessard S, Rivas D, Chen Z, van Denderen B, Watt M, Koch L, et al. Impaired skeletal muscle beta-adrenergic activation and lipolysis are associated with whole-body insulin resistance in rats bred for low intrinsic exercise capacity. Endocrinology. 2009;150:4883-91 pubmed publisher
Jiang J, McDonald P, Dixon T, Franicola D, Zhang X, Nie S, et al. Synthetic protection short interfering RNA screen reveals glyburide as a novel radioprotector. Radiat Res. 2009;172:414-22 pubmed publisher
Liu S, Kapoor M, Denton C, Abraham D, Leask A. Loss of beta1 integrin in mouse fibroblasts results in resistance to skin scleroderma in a mouse model. Arthritis Rheum. 2009;60:2817-21 pubmed publisher
Tietzel I, El Haibi C, Carabeo R. Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma. PLoS ONE. 2009;4:e6499 pubmed publisher
Miao Y, Chen J, Zhang Q, Sun A. Deletion of tau attenuates heat shock-induced injury in cultured cortical neurons. J Neurosci Res. 2010;88:102-10 pubmed publisher
Tang J, LeGros R, Louneva N, Yeh L, Cohen J, Hahn C, et al. Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression. Hum Mol Genet. 2009;18:3851-63 pubmed publisher
Doyle T, Bryant L, Batinic Haberle I, Little J, Cuzzocrea S, Masini E, et al. Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance. Neuroscience. 2009;164:702-10 pubmed publisher
Tatro E, Everall I, Kaul M, Achim C. Modulation of glucocorticoid receptor nuclear translocation in neurons by immunophilins FKBP51 and FKBP52: implications for major depressive disorder. Brain Res. 2009;1286:1-12 pubmed publisher
Brady G, Whiteman H, Spender L, Farrell P. Downregulation of RUNX1 by RUNX3 requires the RUNX3 VWRPY sequence and is essential for Epstein-Barr virus-driven B-cell proliferation. J Virol. 2009;83:6909-16 pubmed publisher
Maier B, Wendt S, Vanselow J, Wallach T, Reischl S, Oehmke S, et al. A large-scale functional RNAi screen reveals a role for CK2 in the mammalian circadian clock. Genes Dev. 2009;23:708-18 pubmed publisher
Tan M, Smith A, Pawlyk B, Xu X, Liu X, Bainbridge J, et al. Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectors. Hum Mol Genet. 2009;18:2099-114 pubmed publisher
Kim M, Ahn K, Park S, Kang H, Jang B, Oh S, et al. SIRT1 regulates tyrosine hydroxylase expression and differentiation of neuroblastoma cells via FOXO3a. FEBS Lett. 2009;583:1183-8 pubmed publisher
Johann D, Rodriguez Canales J, Mukherjee S, Prieto D, Hanson J, Emmert Buck M, et al. Approaching solid tumor heterogeneity on a cellular basis by tissue proteomics using laser capture microdissection and biological mass spectrometry. J Proteome Res. 2009;8:2310-8 pubmed publisher
Han C, Chen T, Yang M, Li N, Liu H, Cao X. Human SCAMP5, a novel secretory carrier membrane protein, facilitates calcium-triggered cytokine secretion by interaction with SNARE machinery. J Immunol. 2009;182:2986-96 pubmed publisher
Lessard A, Savard M, Gobeil F, Pierce J, Pickel V. The neurokinin-3 (NK3) and the neurokinin-1 (NK1) receptors are differentially targeted to mesocortical and mesolimbic projection neurons and to neuronal nuclei in the rat ventral tegmental area. Synapse. 2009;63:484-501 pubmed publisher
Bennewith K, Huang X, Ham C, Graves E, Erler J, Kambham N, et al. The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth. Cancer Res. 2009;69:775-84 pubmed publisher
Huot M, Brown C, Lamarche Vane N, Richard S. An adaptor role for cytoplasmic Sam68 in modulating Src activity during cell polarization. Mol Cell Biol. 2009;29:1933-43 pubmed publisher
Pascreau G, Eckerdt F, Lewellyn A, Prigent C, Maller J. Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes. J Biol Chem. 2009;284:5497-505 pubmed publisher
Hatch N, Li Y, Franceschi R. FGF2 stimulation of the pyrophosphate-generating enzyme, PC-1, in pre-osteoblast cells is mediated by RUNX2. J Bone Miner Res. 2009;24:652-62 pubmed publisher
Aleksic T, Feller S. Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells. Cell Commun Signal. 2008;6:8 pubmed publisher
Emaduddin M, Edelmann M, Kessler B, Feller S. Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells. Cell Commun Signal. 2008;6:7 pubmed publisher
Louneva N, Cohen J, Han L, Talbot K, Wilson R, Bennett D, et al. Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease. Am J Pathol. 2008;173:1488-95 pubmed publisher
Spinner D, Cho I, Park S, Kim J, Meeker H, Ye X, et al. Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice. J Virol. 2008;82:10701-8 pubmed publisher
Nielsen A, Hojman P, Erikstrup C, Fischer C, Plomgaard P, Mounier R, et al. Association between interleukin-15 and obesity: interleukin-15 as a potential regulator of fat mass. J Clin Endocrinol Metab. 2008;93:4486-93 pubmed publisher
De Gasperi R, Rocher A, Sosa M, Wearne S, Perez G, Friedrich V, et al. The IRG mouse: a two-color fluorescent reporter for assessing Cre-mediated recombination and imaging complex cellular relationships in situ. Genesis. 2008;46:308-17 pubmed publisher
Constantinou T, Baumann F, Lacher M, Saurer S, Friis R, Dharmarajan A. SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation. J Mol Signal. 2008;3:10 pubmed publisher
Shen J, Edwards N, Hong Y, Murray G. Isofagomine increases lysosomal delivery of exogenous glucocerebrosidase. Biochem Biophys Res Commun. 2008;369:1071-5 pubmed publisher
Plomgaard P, Nielsen A, Fischer C, Mortensen O, Broholm C, Penkowa M, et al. Associations between insulin resistance and TNF-alpha in plasma, skeletal muscle and adipose tissue in humans with and without type 2 diabetes. Diabetologia. 2007;50:2562-71 pubmed
Nielsen A, Mounier R, Plomgaard P, Mortensen O, Penkowa M, Speerschneider T, et al. Expression of interleukin-15 in human skeletal muscle effect of exercise and muscle fibre type composition. J Physiol. 2007;584:305-12 pubmed
Alimirah F, Panchanathan R, Davis F, Chen J, Choubey D. Restoration of p53 expression in human cancer cell lines upregulates the expression of Notch1: implications for cancer cell fate determination after genotoxic stress. Neoplasia. 2007;9:427-34 pubmed
Autret A, Martin Latil S, Mousson L, Wirotius A, Petit F, Arnoult D, et al. Poliovirus induces Bax-dependent cell death mediated by c-Jun NH2-terminal kinase. J Virol. 2007;81:7504-16 pubmed
Horn V, Thélu J, Garcia A, Albiges Rizo C, Block M, Viallet J. Functional interaction of Aurora-A and PP2A during mitosis. Mol Biol Cell. 2007;18:1233-41 pubmed
Tarulli G, Stanton P, Lerchl A, Meachem S. Adult sertoli cells are not terminally differentiated in the Djungarian hamster: effect of FSH on proliferation and junction protein organization. Biol Reprod. 2006;74:798-806 pubmed
Bozzo C, Spolaore B, Toniolo L, Stevens L, Bastide B, Cieniewski Bernard C, et al. Nerve influence on myosin light chain phosphorylation in slow and fast skeletal muscles. FEBS J. 2005;272:5771-85 pubmed
product information
Catalog Number :
A3853
Product Name :
Monoclonal Anti-Actin antibody produced in mouse
Product Type :
ANTIBODIES - SIAL
Product Group :
Protein & Pathway Technologies
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
unconjugated
Clone Name :
AC-40
Product Description :
clone AC-40, purified from hybridoma cell culture
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA