This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Acylase I from porcine kidney
catalog :
A3010
citations: 34
Reference
Masania J, Faustmann G, Anwar A, Hafner Giessauf H, Rajpoot N, Grabher J, et al. Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health. Oxid Med Cell Longev. 2019;2019:4851323 pubmed publisher
Özcan S, Dieser M, Parker A, Balasubramanian N, Foreman C. Quorum sensing inhibition as a promising method to control biofilm growth in metalworking fluids. J Ind Microbiol Biotechnol. 2019;: pubmed publisher
Fennell T, Mathews J, Snyder R, Hong Y, Watson S, Black S, et al. Metabolism and disposition of 2-ethylhexyl-p-methoxycinnamate following oral gavage and dermal exposure in Harlan Sprague Dawley rats and B6C3F1/N mice and in hepatocytes in vitro. Xenobiotica. 2017;:1-15 pubmed publisher
Waidyanatha S, Mathews J, Patel P, Black S, Snyder R, Fennell T. Disposition of bisphenol AF, a bisphenol A analogue, in hepatocytes in vitro and in male and female Harlan Sprague-Dawley rats and B6C3F1/N mice following oral and intravenous administration. Xenobiotica. 2015;45:811-9 pubmed publisher
Golden E, Paterson R, Tie W, Anandan A, Flematti G, Molla G, et al. Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity. Biochem J. 2013;451:217-26 pubmed publisher
Shi H, Hayes M, Kirana C, Miller R, Keating J, Stubbs R. Overexpression of aminoacylase 1 is associated with colorectal cancer progression. Hum Pathol. 2013;44:1089-97 pubmed publisher
Tsirulnikov K, Abuladze N, Vahi R, Hasnain H, Phillips M, Ryan C, et al. Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein. FEBS Lett. 2012;586:3799-804 pubmed publisher
Tsirulnikov K, Abuladze N, Bragin A, Faull K, Cascio D, Damoiseaux R, et al. Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal. Toxicol Appl Pharmacol. 2012;263:303-14 pubmed publisher
Stocker P, Brunel J, de Rezende L, do Amaral A, Morelli X, Roche P, et al. Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides. Biochimie. 2012;94:1668-75 pubmed publisher
Kuhns E, Seidl Adams I, Tumlinson J. Heliothine caterpillars differ in abundance of a gut lumen aminoacylase (L-ACY-1)-Suggesting a relationship between host preference and fatty acid amino acid conjugate metabolism. J Insect Physiol. 2012;58:408-12 pubmed publisher
Kuhns E, Seidl Adams I, Tumlinson J. A lepidopteran aminoacylase (L-ACY-1) in Heliothis virescens (Lepidoptera: Noctuidae) gut lumen hydrolyzes fatty acid-amino acid conjugates, elicitors of plant defense. Insect Biochem Mol Biol. 2012;42:32-40 pubmed publisher
Parker B, Taylor I, Woodley J, Ward J, Dalby P. Directed evolution of a thermostable l-aminoacylase biocatalyst. J Biotechnol. 2011;155:396-405 pubmed publisher
Chen A, Hurd R, Gu Y, Wilson D, Cunningham C. (13)C MR reporter probe system using dynamic nuclear polarization. NMR Biomed. 2011;24:514-20 pubmed publisher
Yano S, Haruta H, Ikeda T, Kikuchi T, Murakami M, Moriguchi M, et al. Engineering the substrate specificity of Alcaligenes D-aminoacylase useful for the production of D-amino acids by optical resolution. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879:3247-52 pubmed publisher
Sommer A, Christensen E, Schwenger S, Seul R, Haas D, Olbrich H, et al. The molecular basis of aminoacylase 1 deficiency. Biochim Biophys Acta. 2011;1812:685-90 pubmed publisher
Ernst C, Peschel A. Broad-spectrum antimicrobial peptide resistance by MprF-mediated aminoacylation and flipping of phospholipids. Mol Microbiol. 2011;80:290-9 pubmed publisher
Long P, Stradecki H, Minturn J, Wesley U, Jaworski D. Differential aminoacylase expression in neuroblastoma. Int J Cancer. 2011;129:1322-30 pubmed publisher
Hsieh J, Tsirulnikov K, Sawaya M, Magilnick N, Abuladze N, Kurtz I, et al. Structures of aminoacylase 3 in complex with acetylated substrates. Proc Natl Acad Sci U S A. 2010;107:17962-7 pubmed publisher
Liu X, Yao Q, Wang Y, Chen K. Proteomic analysis of nucleopolyhedrovirus infection resistance in the silkworm, Bombyx mori (Lepidoptera: Bombycidae). J Invertebr Pathol. 2010;105:84-90 pubmed publisher
Dong T, Zhao L, Huang Y, Tan X. Preparation of cross-linked aggregates of aminoacylase from Aspergillus melleus by using bovine serum albumin as an inert additive. Bioresour Technol. 2010;101:6569-71 pubmed publisher
Wardenga R, Lindner H, Hollmann F, Thum O, Bornscheuer U. Increasing the synthesis/hydrolysis ratio of aminoacylase 1 by site-directed mutagenesis. Biochimie. 2010;92:102-9 pubmed publisher
Koreishi M, Nakatani Y, Ooi M, Imanaka H, Imamura K, Nakanishi K. Purification, characterization, molecular cloning, and expression of a new aminoacylase from Streptomyces mobaraensis that can hydrolyze N-(middle/long)-chain-fatty-acyl-L-amino acids as well as N-short-chain-acyl-L-amino acids. Biosci Biotechnol Biochem. 2009;73:1940-7 pubmed
Lam L, Shimamura T, Ishiyama M, Ukeda H. Flow injection analysis of angiotensin I-converting enzyme inhibitory activity with enzymatic reactors. Talanta. 2009;79:1130-4 pubmed publisher
Tsirulnikov K, Abuladze N, Newman D, Ryazantsev S, Wolak T, Magilnick N, et al. Mouse aminoacylase 3: a metalloenzyme activated by cobalt and nickel. Biochim Biophys Acta. 2009;1794:1049-57 pubmed publisher
Zhong Y, Onuki J, Yamasaki T, Ogawa O, Akatsuka S, Toyokuni S. Genome-wide analysis identifies a tumor suppressor role for aminoacylase 1 in iron-induced rat renal cell carcinoma. Carcinogenesis. 2009;30:158-64 pubmed publisher
Wardenga R, Hollmann F, Thum O, Bornscheuer U. Functional expression of porcine aminoacylase 1 in E. coli using a codon optimized synthetic gene and molecular chaperones. Appl Microbiol Biotechnol. 2008;81:721-9 pubmed publisher
Caner V, Cokal Y, Cetin C, Sen A, Karagenc N. The detection of hipO gene by real-time PCR in thermophilic Campylobacter spp. with very weak and negative reaction of hippurate hydrolysis. Antonie Van Leeuwenhoek. 2008;94:527-32 pubmed publisher
Cai K, Chen K, Liu X, Yao Q, Li J. [Differential expression of haemolymph proteome of resistant strain and susceptible strain for BmNPV in Bombyx mori L]. Sheng Wu Gong Cheng Xue Bao. 2008;24:285-90 pubmed
Nishioka M, Tanimoto K, Higashi N, Fukada H, Ishikawa K, Taya M. Alteration of metal ions improves the activity and thermostability of aminoacylase from hyperthermophilic archaeon Pyrococcus horikoshii. Biotechnol Lett. 2008;30:1639-43 pubmed publisher
BIRNBAUM S, Levintow L, KINGSLEY R, GREENSTEIN J. Specificity of amino acid acylases. J Biol Chem. 1952;194:455-70 pubmed
Park R, Fox S. An acylase system related to the utilization of benzoylamino acids by Lactobacillus arabinosus. J Biol Chem. 1960;235:3193-7 pubmed
FONES W, Lee M. Hydrolysis of N-acyl derivatives of alanine and phenylalanine by acylase I and carboxypeptidase. J Biol Chem. 1953;201:847-56 pubmed
Uttamsingh V, Keller D, Anders M. Acylase I-catalyzed deacetylation of N-acetyl-L-cysteine and S-alkyl-N-acetyl-L-cysteines. Chem Res Toxicol. 1998;11:800-9 pubmed
Bommarius A, Drauz K, Klenk H, Wandrey C. Operational stability of enzymes. Acylase-catalyzed resolution of N-acetyl amino acids to enantiomerically pure L-amino acids. Ann N Y Acad Sci. 1992;672:126-36 pubmed
product information
Catalog Number :
A3010
Product Name :
Acylase I from porcine kidney
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
Grade I, lyophilized powder, ?1500 units/mg protein
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA