product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-ATG7 antibody produced in rabbit
catalog :
A2856
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
more info or order :
citations: 58
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 6b
Rocchi A, Yamamoto S, Ting T, Fan Y, SADLEIR K, Wang Y, et al. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease. PLoS Genet. 2017;13:e1006962 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 2c
Wei Y, Chiang W, Sumpter R, Mishra P, Levine B. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. Cell. 2017;168:224-238.e10 pubmed publisher
  • western blot; human; 1:1000; fig 1a
Lee M, Sumpter R, Zou Z, Sirasanagandla S, Wei Y, Mishra P, et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 2017;18:48-60 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Tazi M, Dakhlallah D, Caution K, Gerber M, Chang S, Khalil H, et al. Elevated Mirc1/Mir17-92 cluster expression negatively regulates autophagy and CFTR (cystic fibrosis transmembrane conductance regulator) function in CF macrophages. Autophagy. 2016;12:2026-2037 pubmed
  • western blot; human; loading ...; fig 7b
Shen P, Chen M, He M, Chen L, Song Y, Xiao P, et al. Inhibition of ER?/ERK/P62 cascades induces "autophagic switch" in the estrogen receptor-positive breast cancer cells exposed to gemcitabine. Oncotarget. 2016;7:48501-48516 pubmed publisher
Luciani A, Schumann A, Berquez M, Chen Z, Nieri D, Failli M, et al. Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nat Commun. 2020;11:970 pubmed publisher
You Z, Jiang W, Qin L, Gong Z, Wan W, Li J, et al. Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress. Nat Commun. 2019;10:5792 pubmed publisher
Del Bello B, Marcolongo P, Ciarmela P, Sorbi F, Petraglia F, Luisi S, et al. Autophagy up-regulation by ulipristal acetate as a novel target mechanism in the treatment of uterine leiomyoma: an in vitro study. Fertil Steril. 2019;112:1150-1159 pubmed publisher
Fraser J, Simpson J, Fontana R, Kishi Itakura C, Ktistakis N, Gammoh N. Targeting of early endosomes by autophagy facilitates EGFR recycling and signalling. EMBO Rep. 2019;20:e47734 pubmed publisher
Li M, Liu J, Li S, Feng Y, Yi F, Wang L, et al. Autophagy-related 7 modulates tumor progression in triple-negative breast cancer. Lab Invest. 2019;: pubmed publisher
You Z, Xu Y, Wan W, Zhou L, Li J, Zhou T, et al. TP53INP2 contributes to autophagosome formation by promoting LC3-ATG7 interaction. Autophagy. 2019;15:1309-1321 pubmed publisher
Feng H, Zhao X, Guo Q, Feng Y, Ma M, Guo W, et al. Autophagy resists EMT process to maintain retinal pigment epithelium homeostasis. Int J Biol Sci. 2019;15:507-521 pubmed publisher
Bhatt V, Khayati K, Hu Z, Lee A, Kamran W, Su X, et al. Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient Kras-driven lung tumorigenesis. Genes Dev. 2019;33:150-165 pubmed publisher
Wang C, Wu X, Liu Q, Guo G, Huo W, Zhang Y, et al. Effects of folic acid on growth performance, ruminal fermentation, nutrient digestibility and urinary excretion of purine derivatives in post-weaned dairy calves. Arch Anim Nutr. 2019;73:18-29 pubmed publisher
Poillet Perez L, Xie X, Zhan L, Yang Y, Sharp D, Hu Z, et al. Autophagy maintains tumour growth through circulating arginine. Nature. 2018;563:569-573 pubmed publisher
Gomes da Silva L, Jimenez A, Sauvat A, Xie W, Souquere S, Divoux S, et al. Recruitment of LC3 to damaged Golgi apparatus. Cell Death Differ. 2018;: pubmed publisher
Rizzo M, Beffy P, Del Carratore R, Falleni A, Pretini V, D Aurizio R, et al. Activation of the interferon type I response rather than autophagy contributes to myogenesis inhibition in congenital DM1 myoblasts. Cell Death Dis. 2018;9:1071 pubmed publisher
Nuta G, Gilad Y, Gershoni M, Sznajderman A, Schlesinger T, Bialik S, et al. A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation. Autophagy. 2018;:1-15 pubmed publisher
Winer H, Fraiberg M, Abada A, Dadosh T, Tamim Yecheskel B, Elazar Z. Autophagy differentially regulates TNF receptor Fn14 by distinct mammalian Atg8 proteins. Nat Commun. 2018;9:3744 pubmed publisher
Feng Y, Liu J, Guo W, Guan Y, Xu H, Guo Q, et al. Atg7 inhibits Warburg effect by suppressing PKM2 phosphorylation resulting reduced epithelial-mesenchymal transition. Int J Biol Sci. 2018;14:775-783 pubmed publisher
Wang X, Qi X, Yang B, Chen S, Wang J. Autophagy Benefits the Replication of Egg Drop Syndrome Virus in Duck Embryo Fibroblasts. Front Microbiol. 2018;9:1091 pubmed publisher
Jin J, Britschgi A, Schläfli A, Humbert M, Shan Krauer D, Batliner J, et al. Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxid Med Cell Longev. 2018;2018:1482795 pubmed publisher
Festa B, Chen Z, Berquez M, Debaix H, Tokonami N, Prange J, et al. Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney. Nat Commun. 2018;9:161 pubmed publisher
Sulli G, Rommel A, Wang X, Kolar M, Puca F, Saghatelian A, et al. Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence. Nature. 2018;553:351-355 pubmed publisher
Li W, Yang Y, Ba Z, Li S, Chen H, Hou X, et al. MicroRNA-93 Regulates Hypoxia-Induced Autophagy by Targeting ULK1. Oxid Med Cell Longev. 2017;2017:2709053 pubmed publisher
Wan W, You Z, Xu Y, Zhou L, Guan Z, Peng C, et al. mTORC1 Phosphorylates Acetyltransferase p300 to Regulate Autophagy and Lipogenesis. Mol Cell. 2017;68:323-335.e6 pubmed publisher
Kawano S, Torisu T, Esaki M, Torisu K, Matsuno Y, Kitazono T. Autophagy promotes degradation of internalized collagen and regulates distribution of focal adhesions to suppress cell adhesion. Biol Open. 2017;6:1644-1653 pubmed publisher
Kuss Duerkop S, Wang J, Mena I, White K, Metreveli G, Sakthivel R, et al. Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication. PLoS Pathog. 2017;13:e1006635 pubmed publisher
Liu N, Lei R, Tang M, Cheng W, Luo M, Xu Q, et al. Autophagy is activated to protect renal tubular epithelial cells against iodinated contrast media‑induced cytotoxicity. Mol Med Rep. 2017;16:8277-8282 pubmed publisher
Kim Y, Hood D. Regulation of the autophagy system during chronic contractile activity-induced muscle adaptations. Physiol Rep. 2017;5: pubmed publisher
Hine C, Kim H, Zhu Y, Harputlugil E, Longchamp A, Matos M, et al. Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production. Cell Metab. 2017;25:1320-1333.e5 pubmed publisher
Cao B, Macones C, Mysorekar I. ATG16L1 governs placental infection risk and preterm birth in mice and women. JCI Insight. 2016;1:e86654 pubmed publisher
Cao Q, Liu F, Yang Z, Fu X, Yang Z, Liu Q, et al. Prognostic value of autophagy related proteins ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12, LC3B and p62/SQSTM1 in gastric cancer. Am J Transl Res. 2016;8:3831-3847 pubmed
Kwanten W, Vandewynckel Y, Martinet W, De Winter B, Michielsen P, Van Hoof V, et al. Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice. Am J Physiol Gastrointest Liver Physiol. 2016;311:G599-G609 pubmed publisher
Sousa C, Biancur D, Wang X, Halbrook C, Sherman M, Zhang L, et al. Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature. 2016;536:479-83 pubmed publisher
Gammoh N, Fraser J, Puente C, Syred H, Kang H, Ozawa T, et al. Suppression of autophagy impedes glioblastoma development and induces senescence. Autophagy. 2016;12:1431-9 pubmed publisher
Lu W, Shi Y, Ma Z, Wang G, Liu L, Chuai M, et al. Proper autophagy is indispensable for angiogenesis during chick embryo development. Cell Cycle. 2016;15:1742-54 pubmed publisher
Livingston M, Ding H, Huang S, Hill J, Yin X, Dong Z. Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction. Autophagy. 2016;12:976-98 pubmed publisher
Bauckman K, Mysorekar I. Ferritinophagy drives uropathogenic Escherichia coli persistence in bladder epithelial cells. Autophagy. 2016;12:850-63 pubmed publisher
Grootaert M, da Costa Martins P, Bitsch N, Pintelon I, De Meyer G, Martinet W, et al. Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. Autophagy. 2015;11:2014-2032 pubmed publisher
Herranz D, Ambesi Impiombato A, Sudderth J, Sánchez Martín M, Belver L, Tosello V, et al. Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia. Nat Med. 2015;21:1182-9 pubmed publisher
Chen X, Kondo K, Motoki K, Homma H, Okazawa H. Fasting activates macroautophagy in neurons of Alzheimer's disease mouse model but is insufficient to degrade amyloid-beta. Sci Rep. 2015;5:12115 pubmed publisher
Tsuboi K, Nishitani M, Takakura A, Imai Y, Komatsu M, Kawashima H. Autophagy Protects against Colitis by the Maintenance of Normal Gut Microflora and Secretion of Mucus. J Biol Chem. 2015;290:20511-26 pubmed publisher
Wang J, Wu J, Wu H, Liu X, Chen Y, Wu J, et al. Liraglutide protects pancreatic ?-cells against free fatty acids in vitro and affects glucolipid metabolism in apolipoprotein E-/- mice by activating autophagy. Mol Med Rep. 2015;12:4210-4218 pubmed publisher
Au A, Chen Y, Du L, Smith C, Manole M, Baltagi S, et al. Ischemia-induced autophagy contributes to neurodegeneration in cerebellar Purkinje cells in the developing rat brain and in primary cortical neurons in vitro. Biochim Biophys Acta. 2015;1852:1902-11 pubmed publisher
Milan E, Perini T, Resnati M, Orfanelli U, Oliva L, Raimondi A, et al. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells. Autophagy. 2015;11:1161-78 pubmed publisher
Li J, Qi W, Chen G, Feng D, Liu J, Ma B, et al. Mitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy. Autophagy. 2015;11:1216-29 pubmed publisher
Cabrera S, Maciel M, Herrera I, Nava T, Vergara F, Gaxiola M, et al. Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis. Autophagy. 2015;11:670-84 pubmed publisher
Lee J, Park H, Park S, Ryu S, Meng W, Jurgensmeier J, et al. A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress. PLoS ONE. 2015;10:e0122628 pubmed publisher
Allavena G, Carrarelli P, Del Bello B, Luisi S, Petraglia F, Maellaro E. Autophagy is upregulated in ovarian endometriosis: a possible interplay with p53 and heme oxygenase-1. Fertil Steril. 2015;103:1244-51.e1 pubmed publisher
Strohecker A, Joshi S, Possemato R, Abraham R, Sabatini D, White E. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening. Oncogene. 2015;34:5662-76 pubmed publisher
Xie X, Koh J, Price S, White E, Mehnert J. Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma. Cancer Discov. 2015;5:410-23 pubmed publisher
Niso Santano M, Malik S, Pietrocola F, Bravo San Pedro J, Mariño G, Cianfanelli V, et al. Unsaturated fatty acids induce non-canonical autophagy. EMBO J. 2015;34:1025-41 pubmed publisher
Michiels C, Fransen P, De Munck D, De Meyer G, Martinet W. Defective autophagy in vascular smooth muscle cells alters contractility and Ca²⁺ homeostasis in mice. Am J Physiol Heart Circ Physiol. 2015;308:H557-67 pubmed publisher
Koenig U, Fobker M, Lengauer B, Brandstetter M, Resch G, Gröger M, et al. Autophagy facilitates secretion and protects against degeneration of the Harderian gland. Autophagy. 2015;11:298-313 pubmed publisher
Xu X, Araki K, Li S, Han J, Ye L, Tan W, et al. Autophagy is essential for effector CD8(+) T cell survival and memory formation. Nat Immunol. 2014;15:1152-61 pubmed publisher
Sagnier S, Daussy C, Borel S, Robert Hebmann V, Faure M, Blanchet F, et al. Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes. J Virol. 2015;89:615-25 pubmed publisher
Yue W, Hamai A, Tonelli G, Bauvy C, Nicolas V, Tharinger H, et al. Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance. Autophagy. 2013;9:714-29 pubmed publisher
product information
Catalog Number :
A2856
Product Name :
Anti-ATG7 antibody produced in rabbit
Product Type :
ANTIBODIES - SIAL
Product Group :
Protein & Pathway Technologies
Host Species :
rabbit
Clonality :
polyclonal
Conjugation :
unconjugated
Product Description :
affinity isolated antibody, buffered aqueous solution
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA