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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide
catalog :
A2559
citations: 97
Reference
Wang J, Zhu P, Li R, Ren J, Zhou H. Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission. Redox Biol. 2020;30:101415 pubmed publisher
Kaur P, Dhandayuthapani S, Venkatesan T, Gantor M, Rathinavelu A. Molecular mechanism of C-phycocyanin induced apoptosis in LNCaP cells. Bioorg Med Chem. 2020;28:115272 pubmed publisher
Qu C, Sun J, Xu Q, Lv X, Yang W, Wang F, et al. An inhibitor of apoptosis protein (EsIAP1) from Chinese mitten crab Eriocheir sinensis regulates apoptosis through inhibiting the activity of EsCaspase-3/7-1. Sci Rep. 2019;9:20421 pubmed publisher
Mahajna S, Kadan S, Tietel Z, Saad B, Khasib S, Tumeh A, et al. In Vitro Evaluation of Chemically Analyzed Hypericum Triquetrifolium Extract Efficacy in Apoptosis Induction and Cell Cycle Arrest of the HCT-116 Colon Cancer Cell Line. Molecules. 2019;24: pubmed publisher
Mavrikou S, Tsekouras V, Karageorgou M, Moschopoulou G, Kintzios S. Detection of Superoxide Alterations Induced by 5-Fluorouracil on HeLa Cells with a Cell-Based Biosensor. Biosensors (Basel). 2019;9: pubmed publisher
Wu L, Fang J, Yuan X, Xiong C, Chen L. Adropin reduces hypoxia/reoxygenation-induced myocardial injury via the reperfusion injury salvage kinase pathway. Exp Ther Med. 2019;18:3307-3314 pubmed publisher
Wang M, Cao X, Luan C, Li Z. Hydrogen Sulfide Attenuates Hydrogen Peroxide-Induced Injury in Human Lung Epithelial A549 Cells. Int J Mol Sci. 2019;20: pubmed publisher
Cai X, Yang F, Zhu L, Xia Y, Wu Q, Xue H, et al. Rosmarinic Acid, the Main Effective Constituent of Orthosiphon stamineus, Inhibits Intestinal Epithelial Apoptosis Via Regulation of the Nrf2 Pathway in Mice. Molecules. 2019;24: pubmed publisher
Ren K, Liu W, Tian J, Zhang Y, Peng J, Zhang D, et al. Mitochondrial E3 ubiquitin ligase 1 promotes brain injury by disturbing mitochondrial dynamics in a rat model of ischemic stroke. Eur J Pharmacol. 2019;861:172617 pubmed publisher
Zhang A, Qian Y, Qian J. MicroRNA-152-3p protects neurons from oxygen-glucose-deprivation/reoxygenation-induced injury through upregulation of Nrf2/ARE antioxidant signaling by targeting PSD-93. Biochem Biophys Res Commun. 2019;517:69-76 pubmed publisher
Peng S, Hou Y, Yao J, Fang J. Activation of Nrf2 by costunolide provides neuroprotective effect in PC12 cells. Food Funct. 2019;10:4143-4152 pubmed publisher
Bai F, Zhang B, Hou Y, Yao J, Xu Q, Xu J, et al. Xanthohumol Analogues as Potent Nrf2 Activators against Oxidative Stress Mediated Damages of PC12 Cells. ACS Chem Neurosci. 2019;10:2956-2966 pubmed publisher
Zhang X, Lu Y, Wang J, He N. Overexpression of Brg1 alleviates high glucose-induced retinal ganglion cell apoptosis though regulating Notch/Hes1 signaling. Biochem Biophys Res Commun. 2019;: pubmed publisher
Wang Y, Wang C, Zhang Y, Wang G, Yang H. Pre-administration of luteoline attenuates neonatal sevoflurane-induced neurotoxicity in mice. Acta Histochem. 2019;121:500-507 pubmed publisher
Xie Q, Wang S, Zhao Y, Zhang Z, Qin C, Yang X. MicroRNA-216a suppresses the proliferation and migration of human breast cancer cells via the Wnt/β-catenin signaling pathway. Oncol Rep. 2019;41:2647-2656 pubmed publisher
Kong Y, Li G, Zhang W, Hua X, Zhou C, Xu T, et al. Nicotinamide phosphoribosyltransferase aggravates inflammation and promotes atherosclerosis in ApoE knockout mice. Acta Pharmacol Sin. 2019;: pubmed publisher
Yang X, Zhang Q, Yang X, Zhao M, Yang T, Yao A, et al. PACT cessation overcomes ovarian cancer cell chemoresistance to cisplatin by enhancing p53-mediated apoptotic pathway. Biochem Biophys Res Commun. 2019;: pubmed publisher
Novakova J, Talacko P, Novak P, Valis K. The MEK-ERK-MST1 Axis Potentiates the Activation of the Extrinsic Apoptotic Pathway during GDC-0941 Treatment in Jurkat T Cells. Cells. 2019;8: pubmed publisher
Lan L, Wang Y, Pan Z, Wang B, Yue Z, Jiang Z, et al. Rhamnetin induces apoptosis in human breast cancer cells via the miR-34a/Notch-1 signaling pathway. Oncol Lett. 2019;17:676-682 pubmed publisher
Zhang X, Li P, Zheng Q, Hou J. Lactobacillus acidophilus S-layer protein-mediated inhibition of PEDV-induced apoptosis of Vero cells. Vet Microbiol. 2019;229:159-167 pubmed publisher
Wang G, Ma K, Zhang Y, Hu Z, Liu L, Lu J, et al. Caspase 3/ROCK1 pathway mediates high glucose-induced platelet microparticles shedding. Biochem Biophys Res Commun. 2019;509:596-602 pubmed publisher
Li X, Yi H, Wang H. Sulphur dioxide and arsenic affect male reproduction via interfering with spermatogenesis in mice. Ecotoxicol Environ Saf. 2018;165:164-173 pubmed publisher
Yue J, Chang S, Xiao Z, Qi Y, He J. The protective effect of puerarin on angiotensin II-induced aortic aneurysm formation by the inhibition of NADPH oxidase activation and oxidative stress-triggered AP-1 signaling pathways. Oncol Lett. 2018;16:3327-3332 pubmed publisher
Li D, Luo Z, Ling S, Wu K, Chen G, Cheng J. Mitochondrial apoptotic pathway mediated the Zn-induced lipolysis in yellow catfish Peteobagrus fulvidraco. Chemosphere. 2018;208:907-915 pubmed publisher
Fang Y, Zhao Y, He S, Guo T, Song Q, Guo N, et al. Overexpression of FGF19 alleviates hypoxia/reoxygenation-induced injury of cardiomyocytes by regulating GSK-3β/Nrf2/ARE signaling. Biochem Biophys Res Commun. 2018;503:2355-2362 pubmed publisher
Zhao X, Zhang W, Ji W. MYO5A inhibition by miR-145 acts as a predictive marker of occult neck lymph node metastasis in human laryngeal squamous cell carcinoma. Onco Targets Ther. 2018;11:3619-3635 pubmed publisher
Lian W, Lian H, Li Q, Hu A, Liu S. The venom of spider Haplopelma hainanum suppresses proliferation and induces apoptosis in hepatic cancer cells by caspase activation in vitro. J Ethnopharmacol. 2018;225:169-177 pubmed publisher
Fan L, Wu X, Jin C, Li F, Xiong S, Dong Y. MptpB Promotes Mycobacteria Survival by Inhibiting the Expression of Inflammatory Mediators and Cell Apoptosis in Macrophages. Front Cell Infect Microbiol. 2018;8:171 pubmed publisher
Akazawa K, Sugihara F, Nakamura T, Mizukami S, Kikuchi K. Highly Sensitive Detection of Caspase-3/7 Activity in Living Mice Using Enzyme-Responsive 19F MRI Nanoprobes. Bioconjug Chem. 2018;29:1720-1728 pubmed publisher
Wnuk A, Rzemieniec J, Litwa E, Lasoń W, Kajta M. Prenatal exposure to benzophenone-3 (BP-3) induces apoptosis, disrupts estrogen receptor expression and alters the epigenetic status of mouse neurons. J Steroid Biochem Mol Biol. 2018;182:106-118 pubmed publisher
Li W, Ma Y, Mao Y, Lin T. Dehydrocostus lactone suppresses cell growth and induces apoptosis in recombinant human papilloma virus‑18 HaCaT cells via the PI3K/Akt signaling pathway. Mol Med Rep. 2018;17:7925-7930 pubmed publisher
Li Y, Du Y, Cao J, Gao Q, Li H, Chen Y, et al. MiR-130a inhibition protects rat cardiac myocytes from hypoxia-triggered apoptosis by targeting Smad4. Kardiol Pol. 2018;76:993-1001 pubmed publisher
Jin Y, Xu K, Chen Q, Wang B, Pan J, Huang S, et al. Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway. Exp Cell Res. 2018;362:362-369 pubmed publisher
Yue Z, Si T, Pan Z, Cao W, Yan Z, Jiang Z, et al. Sophoridine suppresses cell growth in human medulloblastoma through FoxM1, NF-κB and AP-1. Oncol Lett. 2017;14:7941-7946 pubmed publisher
Chen O, Cao Z, Li H, Ye Z, Zhang R, Zhang N, et al. High-concentration hydrogen protects mouse heart against ischemia/reperfusion injury through activation of thePI3K/Akt1 pathway. Sci Rep. 2017;7:14871 pubmed publisher
Zhu Z, Yi S, Shan Z, Guo H, Ke S. Effect of isoflurane + N2O inhalation and propofol + fentanyl anesthesia on myocardial function as assessed by cardiac troponin, caspase-3, cyclooxygenase-2 and inducible nitric oxide synthase expression. Exp Ther Med. 2017;14:4377-4382 pubmed publisher
Ding N, Wu H, Tao T, Peng E. NEAT1 regulates cell proliferation and apoptosis of ovarian cancer by miR-34a-5p/BCL2. Onco Targets Ther. 2017;10:4905-4915 pubmed publisher
Wang X, Du Y, Hua Y, Fu M, Niu C, Zhang B, et al. The EspF N-Terminal of Enterohemorrhagic Escherichia coli O157:H7 EDL933w Imparts Stronger Toxicity Effects on HT-29 Cells than the C-Terminal. Front Cell Infect Microbiol. 2017;7:410 pubmed publisher
Cao S, Zhu X, Du L. P38 MAP kinase is involved in oleuropein-induced apoptosis in A549 cells by a mitochondrial apoptotic cascade. Biomed Pharmacother. 2017;95:1425-1435 pubmed publisher
Llanos G, Araujo L, Jimenez I, Moujir L, Rodriguez J, Jimenez C, et al. Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. Eur J Med Chem. 2017;140:52-64 pubmed publisher
Belcher S, Burton C, Cookman C, Kirby M, Miranda G, Saeed F, et al. Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity. BMC Pharmacol Toxicol. 2017;18:63 pubmed publisher
Chao C, Hou S, Huang C, Hou C, Chen P, Liu J. Plumbagin induces apoptosis in human osteosarcoma through ROS generation, endoplasmic reticulum stress and mitochondrial apoptosis pathway. Mol Med Rep. 2017;16:5480-5488 pubmed publisher
Li Z, Gao J, Hu P, Xiong J. Anticancer effects of liriodenine on the cell growth and apoptosis of human breast cancer MCF-7 cells through the upregulation of p53 expression. Oncol Lett. 2017;14:1979-1984 pubmed publisher
Li L, Hou A, Gao X, Zhang J, Zhang L, Wang J, et al. Lentivirus-mediated miR-23a overexpression induces trophoblast cell apoptosis through inhibiting X-linked inhibitor of apoptosis. Biomed Pharmacother. 2017;94:412-417 pubmed publisher
Lim J, Kim H, Kim S, Rhee K, Kim Y. Caspase-2 mediates triglyceride (TG)-induced macrophage cell death. BMB Rep. 2017;50:510-515 pubmed
Zhong Y, Jin C, Gan J, Wang X, Shi Z, Xia X, et al. Apigenin attenuates patulin-induced apoptosis in HEK293 cells by modulating ROS-mediated mitochondrial dysfunction and caspase signal pathway. Toxicon. 2017;137:106-113 pubmed publisher
Li S, Peng W, Li J, Hao G, Geng X, Sun J. Characterization of Japanese flounder (Paralichthys olivaceus) Caspase1 involved in extracellular ATP-mediated immune signaling in fish. Fish Shellfish Immunol. 2017;67:536-545 pubmed publisher
Zhang J, Wang Z, Wu A, Nie J, Pei H, Hu W, et al. Differences in responses to X-ray exposure between osteoclast and osteoblast cells. J Radiat Res. 2017;58:791-802 pubmed publisher
Su Q, Wang Y, Yang X, Li X, Qi Y, He X, et al. Inhibition of Endoplasmic Reticulum Stress Apoptosis by Estrogen Protects Human Umbilical Vein Endothelial Cells Through the PI3 Kinase-Akt Signaling Pathway. J Cell Biochem. 2017;118:4568-4574 pubmed publisher
Meng X, Ji Y, Wan Z, Zhao B, Feng C, Zhao J, et al. Inhibition of miR-363 protects cardiomyocytes against hypoxia-induced apoptosis through regulation of Notch signaling. Biomed Pharmacother. 2017;90:509-516 pubmed publisher
Ni Z, Tao L, Xiaohui X, Zelin Z, Jiangang L, Zhao S, et al. Polydatin impairs mitochondria fitness and ameliorates podocyte injury by suppressing Drp1 expression. J Cell Physiol. 2017;232:2776-2787 pubmed publisher
Shi S, Guo K, Wang X, Chen H, Min J, Qi S, et al. Toxicity study of oxalicumone A, derived from a marine-derived fungus Penicillium oxalicum, in cultured renal epithelial cells. Mol Med Rep. 2017;15:2611-2619 pubmed publisher
Ruiz M, Okada H, Dahlback B. HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium. Lipids Health Dis. 2017;16:36 pubmed publisher
Chen A, Li H, Li Y, Zeng H. Naphthazarin suppresses cell proliferation and induces apoptosis in human colorectal cancer cells via the B-cell lymphoma 2/B-cell associated X protein signaling pathway. Oncol Lett. 2016;12:5211-5216 pubmed publisher
Yang Z, Liu Y, Shi C, Zhang Y, Lv R, Zhang R, et al. Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways. Oncol Rep. 2017;37:1011-1019 pubmed publisher
Shen M, Jiang Y, Guan Z, Cao Y, Sun S, Liu H. FSH protects mouse granulosa cells from oxidative damage by repressing mitophagy. Sci Rep. 2016;6:38090 pubmed publisher
Liu Q, Zhao G, Zhou C, Farlow M, Du Y, Xu G, et al. Oxaloacetate and adipose stromal cells-conditional medium synergistically protected potassium/serum deprivation-induced neuronal apoptosis. Brain Res Bull. 2017;128:7-12 pubmed publisher
Diogo C, Deus C, Lebiedzinska Arciszewska M, Wojtala A, Wieckowski M, Oliveira P. Carvedilol and antioxidant proteins in a type I diabetes animal model. Eur J Clin Invest. 2017;47:19-29 pubmed publisher
Wang Y, Zhang S, Xu Y, Zhang Y, Guan H, Li X, et al. Upregulation of miR-192 inhibits cell growth and invasion and induces cell apoptosis by targeting TCF7 in human osteosarcoma. Tumour Biol. 2016;37:15211-15220 pubmed
Lambuk L, Jafri A, Arfuzir N, Iezhitsa I, Agarwal R, Rozali K, et al. Neuroprotective Effect of Magnesium Acetyltaurate Against NMDA-Induced Excitotoxicity in Rat Retina. Neurotox Res. 2017;31:31-45 pubmed publisher
Pino M, Marotte C, Verstraeten S. Epidermal growth factor prevents thallium(I)- and thallium(III)-mediated rat pheochromocytoma (PC12) cell apoptosis. Arch Toxicol. 2017;91:1157-1174 pubmed publisher
Ronsisvalle S, Aricò G, Cova A, Blanco P, Amata E, Pappalardo M, et al. Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist. Pharmazie. 2016;71:146-51 pubmed
Ku H, Kwon O, Kang B, Lee D, Lee H, Park J. IDH2 knockdown sensitizes tumor cells to emodin cytotoxicity in vitro and in vivo. Free Radic Res. 2016;50:1089-1097 pubmed
Uranga R, Alza N, Conde M, Antollini S, Salvador G. Phosphoinositides: Two-Path Signaling in Neuronal Response to Oligomeric Amyloid ? Peptide. Mol Neurobiol. 2017;54:3236-3252 pubmed publisher
Chu W, Wei W, Yu S, Han H, Shi X, Sun W, et al. C2C12 myotubes inhibit the proliferation and differentiation of 3T3-L1 preadipocytes by reducing the expression of glucocorticoid receptor gene. Biochem Biophys Res Commun. 2016;472:68-74 pubmed publisher
Wang D, Zhu H, Li S, Yang J, Xiao Y, Kang Q, et al. Crude Saponins of Panax notoginseng Have Neuroprotective Effects To Inhibit Palmitate-Triggered Endoplasmic Reticulum Stress-Associated Apoptosis and Loss of Postsynaptic Proteins in Staurosporine Differentiated RGC-5 Retinal Ganglion Cells. J Agric Food Chem. 2016;64:1528-39 pubmed publisher
He B, Tao H, Liu S, Wei A, Pan F, Chen R, et al. Carboxymethylated chitosan protects rat chondrocytes from NO‑induced apoptosis via inhibition of the p38/MAPK signaling pathway. Mol Med Rep. 2016;13:2151-8 pubmed publisher
Qu X, Fan L, Zhong T, Li G, Xia X, Long H, et al. The nematocysts venom of Chrysaora helvola Brandt leads to apoptosis-like cell death accompanied by uncoupling of oxidative phosphorylation. Toxicon. 2016;110:74-8 pubmed publisher
Hwang H, Yang C, Park S, Kim H. Monosodium Urate Crystal-Induced Chondrocyte Death via Autophagic Process. Int J Mol Sci. 2015;16:29265-77 pubmed publisher
Litwa E, Rzemieniec J, Wnuk A, Lason W, Krzeptowski W, Kajta M. RXRα, PXR and CAR xenobiotic receptors mediate the apoptotic and neurotoxic actions of nonylphenol in mouse hippocampal cells. J Steroid Biochem Mol Biol. 2016;156:43-52 pubmed publisher
Soto Nuñez M, Díaz Morales K, Cuautle Rodríguez P, Torres Flores V, Lopez Gonzalez J, Mandoki Weitzner J, et al. Single-cell microinjection assay indicates that 7-hydroxycoumarin induces rapid activation of caspase-3 in A549 cancer cells. Exp Ther Med. 2015;10:1789-1795 pubmed
Qu X, Xia X, Lai Z, Zhong T, Li G, Fan L, et al. Apoptosis-like cell death induced by nematocyst venom from Chrysaora helvola Brandt jellyfish and an in vitro evaluation of commonly used antidotes. Comp Biochem Physiol C Toxicol Pharmacol. 2016;180:31-9 pubmed publisher
Kraus D, Reckenbeil J, Wenghoefer M, Stark H, Frentzen M, Allam J, et al. Ghrelin promotes oral tumor cell proliferation by modifying GLUT1 expression. Cell Mol Life Sci. 2016;73:1287-99 pubmed publisher
Zhao P, Li F, Gao W, Wang J, Fu L, Chen Y, et al. Angiotensin1-7 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress by preventing ROS-associated mitochondrial dysfunction and activating the Akt signaling pathway. Acta Histochem. 2015;117:803-10 pubmed publisher
Iloki Assanga S, Lewis Luján L, Fernández Angulo D, Gil Salido A, Lara Espinoza C, Rubio Pino J. Retino-protective effect of Bucida buceras against oxidative stress induced by H2O2 in human retinal pigment epithelial cells line. BMC Complement Altern Med. 2015;15:254 pubmed publisher
Peng S, Zhang B, Yao J, Duan D, Fang J. Dual protection of hydroxytyrosol, an olive oil polyphenol, against oxidative damage in PC12 cells. Food Funct. 2015;6:2091-100 pubmed publisher
Xu W, Xu B, Yao Y, Yu X, Shen J. The novel HDAC inhibitor AR-42-induced anti-colon cancer cell activity is associated with ceramide production. Biochem Biophys Res Commun. 2015;463:545-50 pubmed publisher
Bonilla X, Dakir E, Mollinedo F, Gajate C. Endoplasmic reticulum targeting in Ewing's sarcoma by the alkylphospholipid analog edelfosine. Oncotarget. 2015;6:14596-613 pubmed
Zhang Y, Liu B, Luo X, Li T, Zhang J, Peng J, et al. Nuclear cardiac myosin light chain 2 modulates NADPH oxidase 2 expression in myocardium: a novel function beyond muscle contraction. Basic Res Cardiol. 2015;110:38 pubmed publisher
Li W, Qi Z, Wei Z, Liu S, Wang P, Chen Y, et al. Paeoniflorin inhibits proliferation and induces apoptosis of human glioma cells via microRNA-16 upregulation and matrix metalloproteinase-9 downregulation. Mol Med Rep. 2015;12:2735-40 pubmed publisher
Cui W, Huang Z, He H, Gu N, Qin G, Lv J, et al. MiR-1188 at the imprinted Dlk1-Dio3 domain acts as a tumor suppressor in hepatoma cells. Mol Biol Cell. 2015;26:1416-27 pubmed publisher
Li N, Liu K, Yuan H, Zhu J, Yu G, Xie J, et al. The effect of mono-(2-ethylhexyl) phthalate on apoptosis of rat ovarian granulosa cells in vitro. Environ Toxicol Pharmacol. 2015;39:643-50 pubmed publisher
Liu L, Xie H, Xue Y, Liu Y, Li Z, Wang P. Endothelial-monocyte-activating polypeptide II induces rat C6 glioma cell apoptosis via the mitochondrial pathway. Biochem Biophys Res Commun. 2015;457:595-601 pubmed publisher
Chao T, Wang C, Chen Y, Lai C, Chang F, Tsai Y, et al. Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A. Oncotarget. 2015;6:2164-79 pubmed
Fang C, Zhang J, Qi D, Fan X, Luo J, Liu L, et al. Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells. PLoS ONE. 2014;9:e115204 pubmed publisher
Moreira A, Branco A, Sampaio S, Cunha Oliveira T, Martins T, Holy J, et al. Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts. Biochim Biophys Acta. 2014;1842:2468-78 pubmed publisher
Ko S, Kim S, Share A, Lynch V, Park J, Namkung W, et al. Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells. Nat Chem. 2014;6:885-92 pubmed publisher
Rahmani Nezhad S, Safavi M, Pordeli M, Ardestani S, Khosravani L, Pourshojaei Y, et al. Synthesis, in vitro cytotoxicity and apoptosis inducing study of 2-aryl-3-nitro-2H-chromene derivatives as potent anti-breast cancer agents. Eur J Med Chem. 2014;86:562-9 pubmed publisher
Song X, Wang B, Lin S, Jing L, Mao C, Xu P, et al. Astaxanthin inhibits apoptosis in alveolar epithelial cells type II in vivo and in vitro through the ROS-dependent mitochondrial signalling pathway. J Cell Mol Med. 2014;18:2198-212 pubmed publisher
Yang C, Matsuura K, Huang N, Robeson A, Huang B, Zhang L, et al. Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death. Oncogene. 2015;34:3264-72 pubmed publisher
Litwa E, Rzemieniec J, Wnuk A, Lason W, Krzeptowski W, Kajta M. Apoptotic and neurotoxic actions of 4-para-nonylphenol are accompanied by activation of retinoid X receptor and impairment of classical estrogen receptor signaling. J Steroid Biochem Mol Biol. 2014;144 Pt B:334-47 pubmed publisher
Jiang L, Zhao M, Liu T, Wu X, Weng H, Ding Q, et al. Bufalin induces cell cycle arrest and apoptosis in gallbladder carcinoma cells. Tumour Biol. 2014;35:10931-41 pubmed publisher
Kajta M, Litwa E, Rzemieniec J, Wnuk A, Lason W, Zelek Molik A, et al. Isomer-nonspecific action of dichlorodiphenyltrichloroethane on aryl hydrocarbon receptor and G-protein-coupled receptor 30 intracellular signaling in apoptotic neuronal cells. Mol Cell Endocrinol. 2014;392:90-105 pubmed publisher
Shu Y, Bao R, Wu X, Weng H, Ding Q, Cao Y, et al. Baicalin induces apoptosis of gallbladder carcinoma cells in vitro via a mitochondrial-mediated pathway and suppresses tumor growth in vivo. Anticancer Agents Med Chem. 2014;14:1136-45 pubmed
Mohapatra A, Kumar S, Satapathy A, Ravindran B. Caspase dependent programmed cell death in developing embryos: a potential target for therapeutic intervention against pathogenic nematodes. PLoS Negl Trop Dis. 2011;5:e1306 pubmed publisher
Wang X, Shi Q, Xu K, Gao C, Chen C, Li X, et al. Familial CJD associated PrP mutants within transmembrane region induced Ctm-PrP retention in ER and triggered apoptosis by ER stress in SH-SY5Y cells. PLoS ONE. 2011;6:e14602 pubmed publisher
Ramalho R, Viana R, Castro R, Steer C, Low W, Rodrigues C. Apoptosis in transgenic mice expressing the P301L mutated form of human tau. Mol Med. 2008;14:309-17 pubmed publisher
product information
Catalog Number :
A2559
Product Name :
N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥97% (HPLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA