This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
other
product name :
Aggrecan from bovine articular cartilage
catalog :
A1960
citations: 17
Reference
Santamaria S, Yamamoto K, Teráz Orosz A, Koch C, Apte S, de Groot R, et al. Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis. Sci Rep. 2019;9:10914 pubmed publisher
Kalinski A, Kar A, Craver J, Tosolini A, Sleigh J, Lee S, et al. Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. J Cell Biol. 2019;218:1871-1890 pubmed publisher
Matamoros A, Tom V, Wu D, Rao Y, Sharp D, Baas P. Knockdown of Fidgetin Improves Regeneration of Injured Axons by a Microtubule-Based Mechanism. J Neurosci. 2019;39:2011-2024 pubmed publisher
Tran A, Sundar S, Yu M, Lang B, Silver J. Modulation of Receptor Protein Tyrosine Phosphatase Sigma Increases Chondroitin Sulfate Proteoglycan Degradation through Cathepsin B Secretion to Enhance Axon Outgrowth. J Neurosci. 2018;38:5399-5414 pubmed publisher
Brett M, Bomberger H, Doak G, Price M, McCarthy J, Wood D. In vitro elucidation of the role of pericellular matrix in metastatic extravasation and invasion of breast carcinoma cells. Integr Biol (Camb). 2018;10:242-252 pubmed publisher
Kuboyama K, Tanga N, Suzuki R, Fujikawa A, Noda M. Protamine neutralizes chondroitin sulfate proteoglycan-mediated inhibition of oligodendrocyte differentiation. PLoS ONE. 2017;12:e0189164 pubmed publisher
Nganvongpanit K, Pothacharoen P, Suwankong N, Ong Chai S, Kongtawelert P. The effect of doxycycline on canine hip osteoarthritis: design of a 6-months clinical trial. J Vet Sci. 2009;10:239-47 pubmed
Arner E, Pratta M, Trzaskos J, Decicco C, Tortorella M. Generation and characterization of aggrecanase. A soluble, cartilage-derived aggrecan-degrading activity. J Biol Chem. 1999;274:6594-601 pubmed
Hedlund H, Hedbom E, Heineg rd D, Mengarelli Widholm S, Reinholt F, Svensson O. Association of the aggrecan keratan sulfate-rich region with collagen in bovine articular cartilage. J Biol Chem. 1999;274:5777-81 pubmed
Cao L, Yang B. Chondrocyte apoptosis induced by aggrecan G1 domain as a result of decreased cell adhesion. Exp Cell Res. 1999;246:527-37 pubmed
Ishiguro N, Ito T, Ito H, Iwata H, Jugessur H, Ionescu M, et al. Relationship of matrix metalloproteinases and their inhibitors to cartilage proteoglycan and collagen turnover: analyses of synovial fluid from patients with osteoarthritis. Arthritis Rheum. 1999;42:129-36 pubmed
Bolton M, Dudhia J, Bayliss M. Age-related changes in the synthesis of link protein and aggrecan in human articular cartilage: implications for aggregate stability. Biochem J. 1999;337 ( Pt 1):77-82 pubmed
Cao L, Zhang Y, Yang B. Expression of the G1 domain of aggrecan interferes with chondrocyte attachment and adhesion. Matrix Biol. 1998;17:379-92 pubmed
Billington C, Clark I, Cawston T. An aggrecan-degrading activity associated with chondrocyte membranes. Biochem J. 1998;336 ( Pt 1):207-12 pubmed
Watanabe H, Cheung S, Itano N, Kimata K, Yamada Y. Identification of hyaluronan-binding domains of aggrecan. J Biol Chem. 1997;272:28057-65 pubmed
Hardingham T, Fosang A, Dudhia J. The structure, function and turnover of aggrecan, the large aggregating proteoglycan from cartilage. Eur J Clin Chem Clin Biochem. 1994;32:249-57 pubmed
Hardingham T, Muir H. The specific interaction of hyaluronic acid with cartillage proteoglycans. Biochim Biophys Acta. 1972;279:401-5 pubmed
product information
Catalog Number :
A1960
Product Name :
Aggrecan from bovine articular cartilage
Product Type :
3D CELL CULTURE
Product Group :
Cell Biology
Product Description :
lyophilized powder (from a sterile-filtered solution)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA