product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-Aurora-A Kinase antibody, Mouse monoclonal
catalog :
A1231
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
35C1
reactivity :
human, mouse, chicken
application :
western blot, immunoprecipitation
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; 1:50; loading ...; fig 1d
Umstead M, Xiong J, Qi Q, Du Y, Fu H. Aurora kinase A interacts with H-Ras and potentiates Ras-MAPK signaling. Oncotarget. 2017;8:28359-28372 pubmed publisher
  • western blot; chicken; fig 1
Burgess S, Peset I, Joseph N, Cavazza T, Vernos I, Pfuhl M, et al. Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly. PLoS Genet. 2015;11:e1005345 pubmed publisher
Morris E, Kawamura E, Gillespie J, Balgi A, Kannan N, Muller W, et al. Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1. Nat Commun. 2017;8:15289 pubmed publisher
Chen H, Xu X, Wang G, Zhang B, Wang G, Xin G, et al. CDK4 protein is degraded by anaphase-promoting complex/cyclosome in mitosis and reaccumulates in early G1 phase to initiate a new cell cycle in HeLa cells. J Biol Chem. 2017;292:10131-10141 pubmed publisher
Xu J, Yue C, Zhou W, Qian Y, Zhang Y, Wang S, et al. Aurora-A contributes to cisplatin resistance and lymphatic metastasis in non-small cell lung cancer and predicts poor prognosis. J Transl Med. 2014;12:200 pubmed publisher
Xu J, Wu X, Zhou W, Liu A, Wu J, Deng J, et al. Aurora-A identifies early recurrence and poor prognosis and promises a potential therapeutic target in triple negative breast cancer. PLoS ONE. 2013;8:e56919 pubmed publisher
McGavin M, Badour K, Hardy L, Kubiseski T, Zhang J, Siminovitch K. The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis. J Exp Med. 2001;194:1777-87 pubmed
product information
Product No. :
A1231
Product Name :
Anti-Aurora-A Kinase antibody, Mouse monoclonal
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
35C1
Applications/Description :
Suitable for immunocytochemistry; western blot: 0.25-0.5 μg/mL using HeLa total cell extract; indirect ELISA; immunoprecipitation (IP)
Species Reactivity :
mouse, human
Isotype :
IgG2b
Concentration :
~2 mg/mL
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA