This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Amyloid β Protein Fragment 1-40
catalog :
A1075
citations: 15
Reference
Heyl D, Iwaniec B, Esckilsen D, Price D, Guttikonda P, Cooper J, et al. Using Small Peptide Segments of Amyloid-β and Humanin to Examine their Physical Interactions. Protein Pept Lett. 2019;26:502-511 pubmed publisher
Teunissen C, Chiu M, Yang C, Yang S, Scheltens P, Zetterberg H, et al. Plasma Amyloid-β (Aβ42) Correlates with Cerebrospinal Fluid Aβ42 in Alzheimer's Disease. J Alzheimers Dis. 2018;62:1857-1863 pubmed publisher
Xu J, Li D, Zheng T, Lu Y. β-amyloid expression in age-related cataract lens epithelia and the effect of β-amyloid on oxidative damage in human lens epithelial cells. Mol Vis. 2017;23:1015-1028 pubmed
Chou C, Lee Y, Liao C, Huang Y, Fan C. Enhanced expressions of neurodegeneration-associated factors, UPS impairment, and excess A? accumulation in the hippocampus of mice with persistent cerebral toxocariasis. Parasit Vectors. 2017;10:620 pubmed publisher
Huang X, Xing S, Chen C, Yu Z, Chen J. Salidroside protects PC12 cells from Aβ1‑40‑induced cytotoxicity by regulating the nicotinamide phosphoribosyltransferase signaling pathway. Mol Med Rep. 2017;16:2700-2706 pubmed publisher
Ozadali Sari K, Tuylu Kucukkilinc T, Ayazgok B, Balkan A, Unsal Tan O. Novel multi-targeted agents for Alzheimer's disease: Synthesis, biological evaluation, and molecular modeling of novel 2-[4-(4-substitutedpiperazin-1-yl)phenyl]benzimidazoles. Bioorg Chem. 2017;72:208-214 pubmed publisher
Chang L, Zhang Y, Liu J, Song Y, Lv A, Li Y, et al. Differential Regulation of N-Methyl-D-Aspartate Receptor Subunits is an Early Event in the Actions of Soluble Amyloid-β(1-40) Oligomers on Hippocampal Neurons. J Alzheimers Dis. 2016;51:197-212 pubmed publisher
Theda L, Drews M, Zitnik G, Oshima J, Martin G. Aβ 1-40 enhances the proliferation of human diploid fibroblasts. Neurobiol Aging. 2016;38:11-13 pubmed publisher
Ball K, Cruz N, Mrak R, Dienel G. Trafficking of glucose, lactate, and amyloid-beta from the inferior colliculus through perivascular routes. J Cereb Blood Flow Metab. 2010;30:162-76 pubmed publisher
Aksenov M, Aksenova M, Markesbery W, Butterfield D. Amyloid beta-peptide (1-40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA. J Mol Neurosci. 1998;10:181-92 pubmed
Funato H, Yoshimura M, Yamazaki T, Saido T, Ito Y, Yokofujita J, et al. Astrocytes containing amyloid beta-protein (Abeta)-positive granules are associated with Abeta40-positive diffuse plaques in the aged human brain. Am J Pathol. 1998;152:983-92 pubmed
Citron M, Diehl T, Gordon G, Biere A, Seubert P, Selkoe D. Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities. Proc Natl Acad Sci U S A. 1996;93:13170-5 pubmed
Howlett D, Jennings K, Lee D, Clark M, Brown F, Wetzel R, et al. Aggregation state and neurotoxic properties of Alzheimer beta-amyloid peptide. Neurodegeneration. 1995;4:23-32 pubmed
Ueda K, Fukui Y, Kageyama H. Amyloid beta protein-induced neuronal cell death: neurotoxic properties of aggregated amyloid beta protein. Brain Res. 1994;639:240-4 pubmed
Yankner B, Duffy L, Kirschner D. Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science. 1990;250:279-82 pubmed
product information
Catalog Number :
A1075
Product Name :
Amyloid β Protein Fragment 1-40
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥90% (HPLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA