product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-GABA antibody produced in mouse
catalog :
A0310
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GB-69
reactivity :
Mongolian jird, marine lamprey, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 63
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig s1d
Xing Z, Zhang L, Zhang Y, Sun X, Sun X, Yu H, et al. DIP2B Interacts With α-Tubulin to Regulate Axon Outgrowth. Front Cell Neurosci. 2020;14:29 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 11f
Tulloch A, Teo S, Carvajal B, Tessier Lavigne M, Jaworski A. Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse. J Comp Neurol. 2019;527:2948-2972 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1a
Victor M, Richner M, Olsen H, Lee S, Monteys A, Ma C, et al. Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Nat Neurosci. 2018;21:341-352 pubmed publisher
  • immunohistochemistry - frozen section; marine lamprey; 1:1200; loading ...; fig 7a
Barreiro Iglesias A, Fernández López B, Sobrido Cameán D, Anadón R. Organization of alpha-transducin immunoreactive system in the brain and retina of larval and young adult Sea Lamprey (Petromyzon marinus), and their relationship with other neural systems. J Comp Neurol. 2017;525:3683-3704 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 3e
Li S, Zang Z, He J, Chen X, Yu S, Pei Y, et al. Expression of pannexin 1 and 2 in cortical lesions from intractable epilepsy patients with focal cortical dysplasia. Oncotarget. 2017;8:6883-6895 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 5a
Dimidschstein J, Chen Q, Tremblay R, Rogers S, Saldi G, Guo L, et al. A viral strategy for targeting and manipulating interneurons across vertebrate species. Nat Neurosci. 2016;19:1743-1749 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; tbl 1
Patel M, Sons S, Yudintsev G, Lesicko A, Yang L, Taha G, et al. Anatomical characterization of subcortical descending projections to the inferior colliculus in mouse. J Comp Neurol. 2017;525:885-900 pubmed publisher
  • immunohistochemistry; mouse; 1:2500; fig 4
Hughes S, Rodgers J, Hickey D, Foster R, Peirson S, Hankins M. Characterisation of light responses in the retina of mice lacking principle components of rod, cone and melanopsin phototransduction signalling pathways. Sci Rep. 2016;6:28086 pubmed publisher
  • immunohistochemistry; Mongolian jird; 1:1000; fig 1
Zhang T, Huang L, Zhang L, Tan M, Pu M, Pickard G, et al. ON and OFF retinal ganglion cells differentially regulate serotonergic and GABAergic activity in the dorsal raphe nucleus. Sci Rep. 2016;6:26060 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:1000; fig s2
Zhang L, Hernandez V, Vázquez Juárez E, Chay F, Barrio R. Thirst Is Associated with Suppression of Habenula Output and Active Stress Coping: Is there a Role for a Non-canonical Vasopressin-Glutamate Pathway?. Front Neural Circuits. 2016;10:13 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:4000
Scheyltjens I, Laramée M, Van den Haute C, Gijsbers R, Debyser Z, Baekelandt V, et al. Evaluation of the expression pattern of rAAV2/1, 2/5, 2/7, 2/8, and 2/9 serotypes with different promoters in the mouse visual cortex. J Comp Neurol. 2015;523:2019-42 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 1
Yao Y, Cui X, Al Ramahi I, Sun X, Li B, Hou J, et al. A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity. elife. 2015;4: pubmed publisher
  • western blot; mouse; 1:100000
May V, Ettle B, Poehler A, Nuber S, Ubhi K, Rockenstein E, et al. ?-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy. Neurobiol Aging. 2014;35:2357-68 pubmed publisher
  • immunohistochemistry - frozen section; marine lamprey; 1:200
Barreiro Iglesias A, Villar Cerviño V, Villar Cheda B, Anadón R, Rodicio M. Neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and CGRP immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates. J Comp Neurol. 2008;511:438-53 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:5000
Navarro Quiroga I, Hernandez Valdes M, Lin S, Naegele J. Postnatal cellular contributions of the hippocampus subventricular zone to the dentate gyrus, corpus callosum, fimbria, and cerebral cortex. J Comp Neurol. 2006;497:833-45 pubmed
Katow H, Yoshida H, Kiyomoto M. Initial report of γ-aminobutyric acidergic locomotion regulatory system and its 3-mercaptopropionic acid-sensitivity in metamorphic juvenile of sea urchin, Hemicentrotus pulcherrimus. Sci Rep. 2020;10:778 pubmed publisher
Xie Y, Ng N, Safrina O, Ramos C, Ess K, Schwartz P, et al. Comparisons of dual isogenic human iPSC pairs identify functional alterations directly caused by an epilepsy associated SCN1A mutation. Neurobiol Dis. 2020;134:104627 pubmed publisher
Rhee H, Shaib A, Rehbach K, Lee C, Seif P, Thomas C, et al. An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons. Cell Rep. 2019;27:2212-2228.e7 pubmed publisher
Meijer M, Rehbach K, Brunner J, Classen J, Lammertse H, van Linge L, et al. A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons. Cell Rep. 2019;27:2199-2211.e6 pubmed publisher
Falcão A, Meijer M, Scaglione A, Rinwa P, Agirre E, Liang J, et al. PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination. Cell Rep. 2019;27:1090-1102.e10 pubmed publisher
Lacin H, Chen H, Long X, Singer R, Lee T, Truman J. Neurotransmitter identity is acquired in a lineage-restricted manner in the Drosophila CNS. elife. 2019;8: pubmed publisher
Ji M, Zhang X, Chen Z, Wang J, Zhu J. Orexin prevents depressive-like behavior by promoting stress resilience. Mol Psychiatry. 2019;24:282-293 pubmed publisher
Jiang Y, Yan L, Xia L, Lu X, Zhu W, Ding D, et al. Zinc finger E-box-binding homeobox 1 (ZEB1) is required for neural differentiation of human embryonic stem cells. J Biol Chem. 2018;293:19317-19329 pubmed publisher
Boeri J, Le Corronc H, Lejeune F, Le Bras B, Mouffle C, Angelim M, et al. Persistent Sodium Current Drives Excitability of Immature Renshaw Cells in Early Embryonic Spinal Networks. J Neurosci. 2018;38:7667-7682 pubmed publisher
Zhang L, Hernandez V, Swinny J, Verma A, Giesecke T, Emery A, et al. A GABAergic cell type in the lateral habenula links hypothalamic homeostatic and midbrain motivation circuits with sex steroid signaling. Transl Psychiatry. 2018;8:50 pubmed publisher
Bombardi C, Venzi M, Crunelli V, Di Giovanni G. Developmental changes of GABA immunoreactivity in cortico-thalamic networks of an absence seizure model. Neuropharmacology. 2018;136:56-67 pubmed publisher
Pappas S, Liang C, Kim S, Rivera C, Dauer W. TorsinA dysfunction causes persistent neuronal nuclear pore defects. Hum Mol Genet. 2018;27:407-420 pubmed publisher
Baldascino E, Di Cristina G, Tedesco P, Hobbs C, Shaw T, Ponte G, et al. The Gastric Ganglion of Octopus vulgaris: Preliminary Characterization of Gene- and Putative Neurochemical-Complexity, and the Effect of Aggregata octopiana Digestive Tract Infection on Gene Expression. Front Physiol. 2017;8:1001 pubmed publisher
Simmons D, Petko A, Paladini C. Differential expression of long-term potentiation among identified inhibitory inputs to dopamine neurons. J Neurophysiol. 2017;118:1998-2008 pubmed publisher
Huang L, Yuan T, Tan M, Xi Y, Hu Y, Tao Q, et al. A retinoraphe projection regulates serotonergic activity and looming-evoked defensive behaviour. Nat Commun. 2017;8:14908 pubmed publisher
Rao M, Didiano D, Patton J. Neurotransmitter-Regulated Regeneration in the Zebrafish Retina. Stem Cell Reports. 2017;8:831-842 pubmed publisher
Huh C, Zhang B, Victor M, Dahiya S, Batista L, Horvath S, et al. Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts. elife. 2016;5: pubmed publisher
Liu Z, Ciarleglio C, Hamodi A, Aizenman C, Pratt K. A population of gap junction-coupled neurons drives recurrent network activity in a developing visual circuit. J Neurophysiol. 2016;115:1477-86 pubmed publisher
Reifler A, Chervenak A, Dolikian M, Benenati B, Li B, Wachter R, et al. All spiking, sustained ON displaced amacrine cells receive gap-junction input from melanopsin ganglion cells. Curr Biol. 2015;25:2763-2773 pubmed publisher
Xu P, Cao X, He Y, Zhu L, Yang Y, Saito K, et al. Estrogen receptor-? in medial amygdala neurons regulates body weight. J Clin Invest. 2015;125:2861-76 pubmed publisher
Berdyyeva T, Otte S, Aluisio L, Ziv Y, Burns L, Dugovic C, et al. Zolpidem reduces hippocampal neuronal activity in freely behaving mice: a large scale calcium imaging study with miniaturized fluorescence microscope. PLoS ONE. 2014;9:e112068 pubmed publisher
Molina Rueda J, Pascual M, Pissarra J, Gallardo F. A putative role for γ-aminobutyric acid (GABA) in vascular development in pine seedlings. Planta. 2015;241:257-67 pubmed publisher
Ashby R, Zeng G, Leotta A, Tse D, McFadden S. Egr-1 mRNA expression is a marker for the direction of mammalian ocular growth. Invest Ophthalmol Vis Sci. 2014;55:5911-21 pubmed publisher
Liu Y, Liu H, Sauvey C, Yao L, Zarnowska E, Zhang S. Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells. Nat Protoc. 2013;8:1670-9 pubmed publisher
Schiemann J, Schlaudraff F, Klose V, Bingmer M, Seino S, Magill P, et al. K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration. Nat Neurosci. 2012;15:1272-80 pubmed publisher
Ring H, Mendu S, Shirazi Fard S, Birnir B, Hallböök F. GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium. PLoS ONE. 2012;7:e36874 pubmed publisher
Miraucourt L, Silva J, Burgos K, Li J, Abe H, Ruthazer E, et al. GABA expression and regulation by sensory experience in the developing visual system. PLoS ONE. 2012;7:e29086 pubmed publisher
Adrio F, Rodriguez Moldes I, Anadón R. Distribution of glycine immunoreactivity in the brain of the Siberian sturgeon (Acipenser baeri): comparison with ?-aminobutyric acid. J Comp Neurol. 2011;519:1115-42 pubmed publisher
Nigam R, El Nour H, Amatya B, Nordlind K. GABA and GABA(A) receptor expression on immune cells in psoriasis: a pathophysiological role. Arch Dermatol Res. 2010;302:507-15 pubmed publisher
Magnaghi V, Parducz A, Frasca A, Ballabio M, Procacci P, Racagni G, et al. GABA synthesis in Schwann cells is induced by the neuroactive steroid allopregnanolone. J Neurochem. 2010;112:980-90 pubmed publisher
Lundell T, Zhou Q, Doughty M. Neurogenin1 expression in cell lineages of the cerebellar cortex in embryonic and postnatal mice. Dev Dyn. 2009;238:3310-25 pubmed publisher
Zhang X, Cai Y, Chu Y, Chen E, Feng J, Luo X, et al. Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates. Front Neuroanat. 2009;3:17 pubmed publisher
Omelchenko N, Bell R, Sesack S. Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area. Eur J Neurosci. 2009;30:1239-50 pubmed publisher
McPherson C, Mantamadiotis T, Tan S, Lawrence A. Deletion of CREB1 from the dorsal telencephalon reduces motivational properties of cocaine. Cereb Cortex. 2010;20:941-52 pubmed publisher
Constantinople C, Disney A, Maffie J, Rudy B, Hawken M. Quantitative analysis of neurons with Kv3 potassium channel subunits, Kv3.1b and Kv3.2, in macaque primary visual cortex. J Comp Neurol. 2009;516:291-311 pubmed publisher
Barreiro Iglesias A, Cornide Petronio M, Anadón R, Rodicio M. Serotonin and GABA are colocalized in restricted groups of neurons in the larval sea lamprey brain: insights into the early evolution of neurotransmitter colocalization in vertebrates. J Anat. 2009;215:435-43 pubmed publisher
Fukushima T, Ohtsubo T, Tsuda M, Yanagawa Y, Hori Y. Facilitatory actions of serotonin type 3 receptors on GABAergic inhibitory synaptic transmission in the spinal superficial dorsal horn. J Neurophysiol. 2009;102:1459-71 pubmed publisher
Niu L, Cao B, Zhu H, Mei B, Wang M, Yang Y, et al. Impaired in vivo synaptic plasticity in dentate gyrus and spatial memory in juvenile rats induced by prenatal morphine exposure. Hippocampus. 2009;19:649-57 pubmed publisher
Gonchar Y, Wang Q, Burkhalter A. Multiple distinct subtypes of GABAergic neurons in mouse visual cortex identified by triple immunostaining. Front Neuroanat. 2007;1:3 pubmed publisher
Bagley J, LaRocca G, Jimenez D, Urban N. Adult neurogenesis and specific replacement of interneuron subtypes in the mouse main olfactory bulb. BMC Neurosci. 2007;8:92 pubmed
Hoskison M, Yanagawa Y, Obata K, Shuttleworth C. Calcium-dependent NMDA-induced dendritic injury and MAP2 loss in acute hippocampal slices. Neuroscience. 2007;145:66-79 pubmed
Ma L, Hocking J, Hehr C, Schuurmans C, McFarlane S. Zac1 promotes a Müller glial cell fate and interferes with retinal ganglion cell differentiation in Xenopus retina. Dev Dyn. 2007;236:192-202 pubmed
Casini G, Rickman D, Brecha N. Expression of the gamma-aminobutyric acid (GABA) plasma membrane transporter-1 in monkey and human retina. Invest Ophthalmol Vis Sci. 2006;47:1682-90 pubmed
Omelchenko N, Sesack S. Cholinergic axons in the rat ventral tegmental area synapse preferentially onto mesoaccumbens dopamine neurons. J Comp Neurol. 2006;494:863-75 pubmed
Tripodi M, Filosa A, Armentano M, Studer M. The COUP-TF nuclear receptors regulate cell migration in the mammalian basal forebrain. Development. 2004;131:6119-29 pubmed
Edqvist P, Hallböök F. Newborn horizontal cells migrate bi-directionally across the neuroepithelium during retinal development. Development. 2004;131:1343-51 pubmed
Hu L, Zhu D, Yu Z, Wang J, Sun Z, Yao T. Expression of angiotensin II type 1 (AT(1)) receptor in the rostral ventrolateral medulla in rats. J Appl Physiol (1985). 2002;92:2153-61 pubmed
Erdo S, Wolff J. gamma-Aminobutyric acid outside the mammalian brain. J Neurochem. 1990;54:363-72 pubmed
product information
Product No. :
A0310
Product Name :
Monoclonal Anti-GABA antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
GB-69
Applications/Description :
Suitable for dot blot; indirect ELISA; immunohistochemistry: 1:100-1:200 (Using heat-retrieved formalin-fixed, paraffin-embedded human brain and/or cerebellum sections.); immunofluorescence
Species Reactivity :
wide range
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA