This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
AS605240
catalog :
A0233
citations: 13
Reference
Yoshida K, Tajima M, Nagano T, Obayashi K, Ito M, Yamamoto K, et al. Co-Stimulation of Purinergic P2X4 and Prostanoid EP3 Receptors Triggers Synergistic Degranulation in Murine Mast Cells. Int J Mol Sci. 2019;20: pubmed publisher
Shang S, Liu L, Wu X, Fan F, Hu E, Wang L, et al. Inhibition of PI3Kγ by AS605240 Protects tMCAO Mice by Attenuating pro-Inflammatory Signaling and Cytokine Release in Reactive Astrocytes. Neuroscience. 2019;: pubmed publisher
Kunkl M, Mastrogiovanni M, Porciello N, Caristi S, Monteleone E, Arcieri S, et al. CD28 Individual Signaling Up-regulates Human IL-17A Expression by Promoting the Recruitment of RelA/NF-κB and STAT3 Transcription Factors on the Proximal Promoter. Front Immunol. 2019;10:864 pubmed publisher
Yu X, Xia Y, Zeng L, Zhang X, Chen L, Yan S, et al. A blockade of PI3K? signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model. Sci Rep. 2018;8:10988 pubmed publisher
Zhang Y, Zimmer M, Guardia T, Callahan S, Mondal C, Di Martino J, et al. Distant Insulin Signaling Regulates Vertebrate Pigmentation through the Sheddase Bace2. Dev Cell. 2018;45:580-594.e7 pubmed publisher
Vyas F, Nelson C, Freeman F, Boocock D, Hargreaves A, Dickenson J. β2-adrenoceptor-induced modulation of transglutaminase 2 transamidase activity in cardiomyoblasts. Eur J Pharmacol. 2017;813:105-121 pubmed publisher
Chen C, Butz E, Chao Y, Grishchuk Y, Becker L, Heller S, et al. Small Molecules for Early Endosome-Specific Patch Clamping. Cell Chem Biol. 2017;24:907-916.e4 pubmed publisher
Lamana S, Napimoga M, Nascimento A, Freitas F, de Araujo D, Quinteiro M, et al. The anti-inflammatory effect of tramadol in the temporomandibular joint of rats. Eur J Pharmacol. 2017;807:82-90 pubmed publisher
Ultimo S, Simioni C, Martelli A, Zauli G, Evangelisti C, Celeghini C, et al. PI3K isoform inhibition associated with anti Bcr-Abl drugs shows in vitro increased anti-leukemic activity in Philadelphia chromosome-positive B-acute lymphoblastic leukemia cell lines. Oncotarget. 2017;8:23213-23227 pubmed publisher
Silveira A, Laranjeira A, Rodrigues G, Leal P, Cardoso B, Barata J, et al. PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia. Oncotarget. 2015;6:13105-18 pubmed
Filippi I, Morena E, Aldinucci C, Carraro F, Sozzani S, Naldini A. Short-term hypoxia enhances the migratory capability of dendritic cell through HIF-1α and PI3K/Akt pathway. J Cell Physiol. 2014;229:2067-76 pubmed publisher
Castor M, Rezende B, Bernardes P, Vieira A, Vieira E, Arantes R, et al. PI3K? controls leukocyte recruitment, tissue injury, and lethality in a model of graft-versus-host disease in mice. J Leukoc Biol. 2011;89:955-64 pubmed publisher
Wei X, Han J, Chen Z, Qi B, Wang G, Ma Y, et al. A phosphoinositide 3-kinase-gamma inhibitor, AS605240 prevents bleomycin-induced pulmonary fibrosis in rats. Biochem Biophys Res Commun. 2010;397:311-7 pubmed publisher
product information
Catalog Number :
A0233
Product Name :
AS605240
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA