This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Interleukin-6, human (hIL-6)
catalog :
11138600001
citations: 30
Reference
Stubbington M, Mahata B, Svensson V, Deonarine A, Nissen J, Betz A, et al. An atlas of mouse CD4(+) T cell transcriptomes. Biol Direct. 2015;10:14 pubmed publisher
Simamura E, Arikawa T, Ikeda T, Shimada H, Shoji H, Masuta H, et al. Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5. PLoS ONE. 2015;10:e0123232 pubmed publisher
Gordon J, Guy G. The molecules controlling B lymphocytes. Immunol Today. 1987;8:339-44 pubmed publisher
Billiau A. Interferon β2 as a promoter of growth and differentiation of B cells. Immunol Today. 1987;8:84-7 pubmed publisher
Brooks K, Fernandez R, Vitetta E. B cell growth and differentiation factors. Methods Enzymol. 1985;116:372-9 pubmed
Kishimoto T. Factors affecting B-cell growth and differentiation. Annu Rev Immunol. 1985;3:133-57 pubmed
Kikutani H, Taga T, Akira S, Kishi H, Miki Y, Saiki O, et al. Effect of B cell differentiation factor (BCDF) on biosynthesis and secretion of immunoglobulin molecules in human B cell lines. J Immunol. 1985;134:990-5 pubmed
Haegeman G, Content J, Volckaert G, Derynck R, Tavernier J, Fiers W. Structural analysis of the sequence coding for an inducible 26-kDa protein in human fibroblasts. Eur J Biochem. 1986;159:625-32 pubmed
Ikebuchi K, Wong G, Clark S, Ihle J, Hirai Y, Ogawa M. Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proc Natl Acad Sci U S A. 1987;84:9035-9 pubmed
Garman R, Jacobs K, Clark S, Raulet D. B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells. Proc Natl Acad Sci U S A. 1987;84:7629-33 pubmed
Van Damme J, Cayphas S, Van Snick J, Conings R, Put W, Lenaerts J, et al. Purification and characterization of human fibroblast-derived hybridoma growth factor identical to T-cell-derived B-cell stimulatory factor-2 (interleukin-6). Eur J Biochem. 1987;168:543-50 pubmed
Poupart P, Vandenabeele P, Cayphas S, Van Snick J, Haegeman G, Kruys V, et al. B cell growth modulating and differentiating activity of recombinant human 26-kd protein (BSF-2, HuIFN-beta 2, HPGF). EMBO J. 1987;6:1219-24 pubmed
Van Damme J, Opdenakker G, Simpson R, Rubira M, Cayphas S, Vink A, et al. Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor. J Exp Med. 1987;165:914-9 pubmed
Van Snick J, Vink A, Cayphas S, Uyttenhove C. Interleukin-HP1, a T cell-derived hybridoma growth factor that supports the in vitro growth of murine plasmacytomas. J Exp Med. 1987;165:641-9 pubmed
Sehgal P, May L, Tamm I, Vilcek J. Human beta 2 interferon and B-cell differentiation factor BSF-2 are identical. Science. 1987;235:731-2 pubmed
Hirano T, Taga T, Yasukawa K, Nakajima K, Nakano N, Takatsuki F, et al. Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production. Proc Natl Acad Sci U S A. 1987;84:228-31 pubmed
Hirano T, Yasukawa K, Harada H, Taga T, Watanabe Y, Matsuda T, et al. Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature. 1986;324:73-6 pubmed
Brakenhoff J, de Groot E, Evers R, Pannekoek H, Aarden L. Molecular cloning and expression of hybridoma growth factor in Escherichia coli. J Immunol. 1987;139:4116-21 pubmed
Andus T, Geiger T, Hirano T, Northoff H, Ganter U, Bauer J, et al. Recombinant human B cell stimulatory factor 2 (BSF-2/IFN-beta 2) regulates beta-fibrinogen and albumin mRNA levels in Fao-9 cells. FEBS Lett. 1987;221:18-22 pubmed
Muraguchi A, Hirano T, Tang B, Matsuda T, Horii Y, Nakajima K, et al. The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells. J Exp Med. 1988;167:332-44 pubmed
O GARRA A, Umland S, De France T, Christiansen J. 'B-cell factors' are pleiotropic. Immunol Today. 1988;9:45-54 pubmed
Tiebout R, van Boxtel Oosterhof F, Stricker E, Zeijlemaker W. A human hybrid hybridoma. J Immunol. 1987;139:3402-5 pubmed
Wong G, Clark S. Multiple actions of interleukin 6 within a cytokine network. Immunol Today. 1988;9:137-9 pubmed
Kishimoto T, Hirano T. A new interleukin with pleiotropic activities. Bioessays. 1988;9:11-5 pubmed
Zilberstein A, Ruggieri R, Korn J, Revel M. Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines. EMBO J. 1986;5:2529-37 pubmed
Van Snick J, Cayphas S, Vink A, Uyttenhove C, Coulie P, Rubira M, et al. Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas. Proc Natl Acad Sci U S A. 1986;83:9679-83 pubmed
Naitoh Y, Fukata J, Tominaga T, Nakai Y, Tamai S, Mori K, et al. Interleukin-6 stimulates the secretion of adrenocorticotropic hormone in conscious, freely-moving rats. Biochem Biophys Res Commun. 1988;155:1459-63 pubmed
Taga T, Hibi M, Hirata Y, Yamasaki K, Yasukawa K, Matsuda T, et al. Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell. 1989;58:573-81 pubmed
Bazin R, Lemieux R. Increased proportion of B cell hybridomas secreting monoclonal antibodies of desired specificity in cultures containing macrophage-derived hybridoma growth factor (IL-6). J Immunol Methods. 1989;116:245-9 pubmed
Gauldie J, Richards C, Harnish D, Lansdorp P, Baumann H. Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proc Natl Acad Sci U S A. 1987;84:7251-5 pubmed
product information
Catalog Number :
11138600001
Product Name :
Interleukin-6, human (hIL-6)
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
recombinant (E. coli)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA