chemical

N-Desmethylclozapine Norclozapine

HY-G0021

10 mM * 1 mL; 5 mg; 10 mg; 25 mg

106; 96; 168; 360 USD

N-Desmethylclozapine Norclozapine

Chemical

10 mM * 1 mL; 5 mg; 10 mg; 25 mg

106; 96; 168; 360 USD

N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic drug Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist ( EC 50 =115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist [1] [2] .

99.72%

Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.