chemical

Pexidartinib hydrochloride PLX-3397 hydrochloride

HY-16749A

10 mM * 1 mL; 5 mg; 10 mg; 50 mg

55; 50; 70; 150 USD

Pexidartinib hydrochloride PLX-3397 hydrochloride

Chemical

10 mM * 1 mL; 5 mg; 10 mg; 50 mg

55; 50; 70; 150 USD

Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC 50 s of 20 and 10 nM, respectively. Pexidartinib exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Anti-cancer activity [1] .

99.95%

Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.