chemical

Iinerixibat GSK2330672

HY-16643

10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg

325; 90; 270; 450; 1400; 2100 USD

Iinerixibat GSK2330672

Chemical

10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg

325; 90; 270; 450; 1400; 2100 USD

Iinerixibat (GSK2330672) is a highly potent, nonabsorbable ASBT(apical sodium-dependent bile acid transporter) inhibitor (hASBT IC50=42 ± 3 nM) which lowers glucose in an animal model of type 2 diabetes and shows excellent developability properties for evaluating the potential therapeutic utility of a nonabsorbable ASBT inhibitor for treatment of patients with type 2 diabetes.

99.88%

Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.