chemical

Butein 2’,3,4,4’-tetrahydroxy Chalcone

HY-16558

10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg

90; 60; 96; 144; 540; 900 USD

Butein 2’,3,4,4’-tetrahydroxy Chalcone

Chemical

10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg

90; 60; 96; 144; 540; 900 USD

Butein, isolated from Dalbergia odorifera T. Chen , is a cAMP-specific PDE inhibitor with an IC 50 of 10.4 μM for PDE4 [1] . Butein is a specific protein tyrosine kinase inhibitor with IC 50 s of 16 and 65 μM for EGFR and p60 c-src in HepG2 cells [2] . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a [3] . Butein is a SIRT1 activator (STAC).

99.95%

Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.