chemical

Alectinib Hydrochloride CH5424802 Hydrochloride

HY-13011A

10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg

82; 72; 90; 120; 192; 312 USD

Alectinib Hydrochloride CH5424802 Hydrochloride

Chemical

10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg

82; 72; 90; 120; 192; 312 USD

Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC 50 of 1.9 nM and a K d value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC 50 s of 1 nM and 3.5 nM, respectively [1] . Alectinib demonstrates effective central nervous system (CNS) penetration [2] .

99.95%

Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.