chemical

LY3023414

HY-12513

10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg

88; 80; 140; 550; 850 USD

LY3023414

Chemical

10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg

88; 80; 140; 550; 850 USD

LY3023414 potently and selectively inhibits class I PI3K isoforms, DNA-PK , and mTORC1/2 with IC 50 s of 6.07 nM, 77.6 nM, 38 nM, 23.8 nM, 4.24 nM and 165 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, DNA-PK and mTOR, respectively. LY3023414 potently inhibits mTORC1 / 2 at low nanomolar concentrations.

99.77%

Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.