chemical

Rigosertib ON-01910

HY-12037A

10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg

92; 84; 144; 540; 900 USD

Rigosertib ON-01910

Chemical

10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg

92; 84; 144; 540; 900 USD

Rigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle [1] [2] . Rigosertib is a selective and non-ATP-competitive inhibitor of PLK1 with an IC 50 of 9 nM [3] .

98.81%

-20°C, stored under nitrogen