chemical

Rigosertib sodium ON-01910 sodium

HY-12037

10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg

77; 70; 110; 290; 490 USD

Rigosertib sodium ON-01910 sodium

Chemical

10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg

77; 70; 110; 290; 490 USD

Rigosertib sodium (ON-01910 sodium) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3K/Akt pathway, promotes the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle [1] [2] . Rigosertib sodium is a selective and non-ATP-competitive inhibitor of PLK1 with an IC 50 of 9 nM [3] .

99.49%

Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.