antibody

MYLK Antibody

HY-P83388

10 μL;50 μL;100 μL

70;185;300 USD

recombinant

domestic rabbit

nonconjugated

YA3133

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

MYLK Antibody

antibody

Rabbit

Recombinant, Monoclonal

Non-conjugated

YA3133

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human, Mouse, Rat

The related gene, a muscle member of the immunoglobulin related gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. The kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. The related gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudorelated gene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

KMLS; KRP; MLCK; MYLK; myosin light chain kinase; smooth muscle and non-muscle isozymes; myosin light polypeptide kinase; telokin

A synthesized peptide derived from human Myosin light chain kinase

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

WB, IHC-P, ICC/IF, FC

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.