antibody

Indoleamine 2,3-dioxygenase Antibody

HY-P83355

10 μL;50 μL;100 μL

70;185;300 USD

recombinant

domestic rabbit

nonconjugated

YA3100

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

Indoleamine 2,3-dioxygenase Antibody

antibody

Rabbit

Recombinant, Monoclonal

Non-conjugated

YA3100

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human

The related gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. The enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. The enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages The enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.

3-dioxygenase; IDO 1; IDO; IDO1; INDO; indolamine 2; 3 dioxygenase; Indole 2 3 dioxygenase

Recombinant protein of human Indoleamine 2,3-dioxygenase

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

WB, IHC-F, IHC-P, ICC/IF, IP

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.