antibody

HLA DR Antibody

HY-P83339

10 μL;50 μL;100 μL

70;185;300 USD

recombinant

domestic rabbit

nonconjugated

YA3084

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

HLA DR Antibody

antibody

Rabbit

Recombinant, Monoclonal

Non-conjugated

YA3084

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human

HLA-DRA is one of the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. The molecule is expressed on the surface of various antigen presenting cells such as B lymphocytes, dendritic cells, and monocytes/macrophages, and plays a central role in the immune system and response by presenting peptides derived from extracellular proteins, in particular, pathogen-derived peptides to T cells. The alpha chain is approximately 33-35 kDa and its related gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

MLRW; HLA-DRA1; MHC class II antigen DRA; HLA class II histocompatibility antigen; DR alpha chain

A synthesized peptide derived from human HLA-DRA

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

WB, IHC-P, ICC/IF, FC

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.