antibody

DUSP6 Antibody

HY-P82535

10 μL;50 μL;100 μL

70;185;300 USD

recombinant

domestic rabbit

nonconjugated

YA2280

western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

DUSP6 Antibody

antibody

Rabbit

Recombinant, Monoclonal

Non-conjugated

YA2280

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human, Mouse, Rat

The protein encoded by The related gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. The related gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of The family, is localized in the cytoplasm. Mutations in The related gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for The related gene.

HH19; MKP3; PYST1; DUSP6; DUSP6a; Dual specificity phosphatase 6

A synthesized peptide derived from human DUSP6

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

WB, IHC-P, ICC/IF, IP, FC

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.