antibody

VAV1 Antibody

HY-P82416

10 μL;50 μL;100 μL

70;185;300 USD

recombinant

domestic rabbit

nonconjugated

YA2161

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

VAV1 Antibody

antibody

Rabbit

Recombinant, Monoclonal

Non-conjugated

YA2161

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human

The related gene is a member of the VAV related gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for The related gene.

p95; p95vav; Protein vav 1; VAV; vav-T

A synthesized peptide derived from human Vav1/2/3

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

WB, ICC/IF, IP, FC

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.