antibody

SynGAP Antibody

HY-P81944

10 μL;50 μL;100 μL

70;185;300 USD

recombinant

domestic rabbit

nonconjugated

YA1689

SynGAP Antibody

antibody

Rabbit

Recombinant, Monoclonal

Non-conjugated

YA1689

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Rat

The related gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of The related gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants.

MRD5; p135 SynGAP; RASA1; RASA5; SYNGAP1

A synthetic peptide of human SynGAP

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

WB

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.