antibody

Phospholamban Antibody

HY-P81877

10 μL;50 μL;100 μL

70;185;300 USD

recombinant

domestic rabbit

nonconjugated

YA1622

western blot, immunoprecipitation, immunohistochemistry - paraffin section

Phospholamban Antibody

antibody

Rabbit

Recombinant, Monoclonal

Non-conjugated

YA1622

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human, Mouse, Rat

The protein encoded by The related gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in The related gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.

PLN; PLB; Cardiac phospholamban; PLB

Recombinant protein of human Phospholamban

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

WB, IHC-P, IP

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.