Phospho-Phospholamban | MedChem Express LLC HY-P81873 product information

product summary

company name :

MedChem Express LLC

product type :

antibody

product name :

Phospho-Phospholamban

catalog :

HY-P81873

quantity :

10 μL;50 μL;100 μL

price :

70;185;300 USD

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

YA1618

reactivity :

human

application :

western blot

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P81873

Product Name :

Phospho-Phospholamban

Product Type :

antibody

Host Species :

Rabbit

Clonality :

Recombinant, Monoclonal

Conjugation :

Non-conjugated

Clone Name :

YA1618

Size :

10 μL;50 μL;100 μL

List Price :

70;185;300 USD

Product Description :

Primary Antibodies

CrossReactivity :

Human, Mouse

Background :

The protein encoded by The related gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in The related gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.

ALTnames :

PLN; PLB; Cardiac phospholamban; PLB

Immunogen :

A synthetic phosphopeptide corresponding to residues surrounding Ser16 of human Phospholamban

Buffer :

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application Summary :

Storage :

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

more info or order :

MedChem Express LLC product webpage