antibody

IGF2R Antibody

HY-P81754

10 μL;50 μL;100 μL

70;185;300 USD

recombinant

domestic rabbit

nonconjugated

YA1499

western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

IGF2R Antibody

antibody

Rabbit

Recombinant, Monoclonal

Non-conjugated

YA1499

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human, Mouse, Rat

The related gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. The receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of The related gene has been association with risk of hepatocellular carcinoma. The orthologous mouse related gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human related gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).

IGF2R; MPRI; Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; CD222

A synthesized peptide derived from human M6PR

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

WB, IHC-P, ICC/IF, IP, FC

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.