antibody

SKP2 Antibody

HY-P81587

10 μL;50 μL;100 μL

70;185;300 USD

recombinant

domestic rabbit

nonconjugated

YA1332

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

SKP2 Antibody

antibody

Rabbit

Recombinant, Monoclonal

Non-conjugated

YA1332

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human, Mouse, Rat

The related gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by The related gene belongs to the Fbls class; in addition to an F-box, The protein contains 10 tandem leucine-rich repeats. The protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, The related gene is established as a protooncorelated gene causally involved in the pathorelated genesis of lymphomas. Alternative splicing of The related gene related generates three transcript variants encoding different isoforms.

SKP2; FBXL1; S-phase kinase-associated protein 2; Cyclin-A/CDK2-associated protein p45; F-box protein Skp2; F-box/LRR-repeat protein 1; p45skp2

A synthesized peptide derived from human SKP2

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

WB, IHC-P, ICC/IF, FC

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.